LOCUS       NZ_CP034414            32453 bp    DNA     circular CON 27-MAY-2024
DEFINITION  Bacillus safensis strain BLXSC chromosome.
ACCESSION   NZ_CP034414
VERSION     NZ_CP034414.1
KEYWORDS    RefSeq.
SOURCE      Bacillus safensis
  ORGANISM  Bacillus safensis
            Bacteria; Bacillota; Bacilli; Bacillales; Bacillaceae; Bacillus.
REFERENCE   1  (bases 1 to 3801264)
  AUTHORS   Saroj,D.B. and Gupta,A.K.
  TITLE     Full genome sequence for characterization of the strain BLXSC Safety
            evaluation of the strain through multidisciplinary approach
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 3801264)
  AUTHORS   Saroj,D.B. and Gupta,A.K.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-DEC-2018) Applied Microbiology Laboratory, Advanced
            Enzyme Technologies Limited, 5th Floor, A Wing, Sun Magnetica, LIC
            Service Road, Louiswadi, Thane, Maharashtra 400 604, India
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: 25-NOV-2018
            Assembly Method                   :: MaSuRCA v. 3.2.2
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 355.0x
            Sequencing Technology :: Illumina MiSeq; Oxford Nanopore GridION
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_023524005.1-RS_2024_05_27
            Annotation Date                   :: 05/27/2024 04:40:03
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,916
            CDSs (total)                      :: 3,803
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 113
            rRNAs                             :: 9, 9, 9 (5S, 16S, 23S)
            complete rRNAs                    :: 9, 9, 9 (5S, 16S, 23S)
            tRNAs                             :: 81
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 38
            CDSs (without protein)            :: 38
            Pseudo Genes (ambiguous residues) :: 0 of 38
            Pseudo Genes (frameshifted)       :: 21 of 38
            Pseudo Genes (incomplete)         :: 20 of 38
            Pseudo Genes (internal stop)      :: 7 of 38
            Pseudo Genes (multiple problems)  :: 9 of 38
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 08:04:02
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 2419188
            Orig. end                         :: 2451641
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP034414.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..32453
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="betalactone"
                     /region_number="9"
                     /rules="(HMGL-like and AMP-binding)"
                     /tool="antismash"
     cand_cluster    1..32453
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(HMGL-like and AMP-binding)"
                     /kind="single"
                     /product="betalactone"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..32453
                     /aStool="rule-based-clusters"
                     /category="other"
                     /contig_edge="False"
                     /core_location="[10000:22453](-)"
                     /cutoff="10000"
                     /detection_rule="(HMGL-like and AMP-binding)"
                     /neighbourhood="10000"
                     /product="betalactone"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..22453)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="(HMGL-like and AMP-binding)"
                     /neighbourhood="10000"
                     /product="betalactone"
                     /protocluster_number="1"
     gene            complement(852..2513)
                     /gene="lonB"
                     /locus_tag="EI692_RS12505"
                     /old_locus_tag="EI692_12590"
     CDS             complement(852..2513)
                     /GO_function="GO:0004252 - serine-type endopeptidase
                     activity [Evidence IEA]"
                     /GO_function="GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /GO_process="GO:0006508 - proteolysis [Evidence IEA]"
                     /GO_process="GO:0030436 - asexual sporulation [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="lonB"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_390699.1"
                     /locus_tag="EI692_RS12505"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EI692_12590"
                     /product="ATP-dependent protease LonB"
                     /protein_id="WP_249856339.1"
                     /transl_table=11
                     /translation="MSWTGIVLFIQLFFGIVIGLYFWNLLRNQRTQKVTIDKESKKEME
                     ALRKMRSIKLSEPLSERVRPKGFQDIVGQEDGIRALKAALCGPNPQHVIVYGPPGVGKT
                     AAARLVMEEAKRHADSPFKKDAVFVELDATTARFDERGIADPLIGSVHDPIYQGAGAMG
                     QAGIPQPKQGAVTHAHGGVLFIDEIGELHPIQMNKMLKVLEDRKVFLDSAYYSEENTQI
                     PNHIHDIFQNGLPADFRLIGATTRTPEEIPPAIRSRCLEIFFKDLDQHELKIVAAKAVQ
                     KIEKELSDEGLNLLTSYVKNGREAVNMVQIAAGMAVTENRKDITIEDVEWVIHSSQLTP
                     RYEQKVPEKPKVGVVNGLAVYGPNSGALLEIEVNICKALEKGSINITGIAEEESIGNQS
                     KSIRRKSMAKGSVENVLTVLRNLGIRTNEYDIHINFPGGAPIDGPSAGIAMATAIFSAI
                     HQIPIDHLTAMTGEIGLQGQVKPIGGVIPKIKAAKQAGATTVIIPYDNQQSILKEIEGV
                     TIVPVKHFQEVLDQCLVNPPDEKKDGLEDEMKRKSV"
     gene            complement(2651..3916)
                     /gene="clpX"
                     /locus_tag="EI692_RS12510"
                     /old_locus_tag="EI692_12595"
     CDS             complement(2651..3916)
                     /EC_number="3.4.21.92"
                     /GO_component="GO:0009368 - endopeptidase Clp complex
                     [Evidence IEA]"
                     /GO_function="GO:0004252 - serine-type endopeptidase
                     activity [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0051082 - unfolded protein binding
                     [Evidence IEA]"
                     /GO_process="GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /gene="clpX"
                     /gene_functions="other (smcogs) SMCOG1223: ATPase"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_390700.2"
                     /locus_tag="EI692_RS12510"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EI692_12595"
                     /product="ATP-dependent protease ATP-binding subunit ClpX"
                     /protein_id="WP_024423180.1"
                     /transl_table=11
                     /translation="MFKFNEEKGQLKCSFCGKTQDQVRKLVAGPGVYICDECIELCTEI
                     VEEELGTEEEVEFKDVPKPHEIREILDEYVIGQDNAKKSLAVAVYNHYKRINSNSKIDD
                     VELSKSNISMIGPTGSGKTLLAQTLARILNVPFAIADATSLTEAGYVGEDVENILLKLI
                     QAADYDVEKAEKGIIYIDEIDKVARKSENPSITRDVSGEGVQQALLKILEGTVASVPPQ
                     GGRKHPHQEFIQIDTTNILFICGGAFDGIEQIIKRRLGQKVIGFGAENKVEDLEKEVLL
                     SKVLPEDLLRFGLIPEFIGRLPVIASLEPLDEKALVEILTKPKNALVKQYTKMLELDDV
                     ELEFEEDALSEIAKKAIERKTGARGLRSIIEGIMLDVMFDLPSRDDIEKCVITGATVAD
                     GEPPRLVLKDGTVVNKDTKTSA"
     gene            complement(4168..5442)
                     /gene="tig"
                     /locus_tag="EI692_RS12515"
                     /old_locus_tag="EI692_12600"
     CDS             complement(4168..5442)
                     /EC_number="5.2.1.8"
                     /GO_component="GO:0005854 - nascent polypeptide-associated
                     complex [Evidence IEA]"
                     /GO_function="GO:0003755 - peptidyl-prolyl cis-trans
                     isomerase activity [Evidence IEA]"
                     /GO_function="GO:0051082 - unfolded protein binding
                     [Evidence IEA]"
                     /GO_process="GO:0051083 - 'de novo' cotranslational protein
                     folding [Evidence IEA]"
                     /codon_start=1
                     /gene="tig"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_390701.1"
                     /locus_tag="EI692_RS12515"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EI692_12600"
                     /product="trigger factor"
                     /protein_id="WP_025092483.1"
                     /transl_table=11
                     /translation="MSVKWEKQEGNEGVLTVEVDAETFNKALDDAFKKVVKQVSIPGFR
                     KGKVPRGLFEQRFGVESLYQDALDILLPVEYPKAIDEAGIEPVDRPEIDVEKIEKGENL
                     IFTAKVTVKPEVKLGDYKGLNVEKDDTAVTDEDVQEELKGMQNRQAELVVKEEGAIENG
                     DTVVLDFEGFVDGEAFEGGKAENYSLEVGSGSFIPGFEEQLVGLEAGAEKDVEVTFPEE
                     YHAEDLAGKPAVFKVKIHEIKAKELPALDDEFAKDVDEEVETLAELTEKTKKRLEEAKE
                     NEAEGKLREELVAKASENAEVDIPQAMVDTELDRMMKEFEQRLQMQGMNLELYFQFSGQ
                     DENALKEQMKEDAAKRVKSNLTLEAIAAAENLQVSDEEVEEELSKMAEAYNMPIENIKQ
                     AIGSTEAMKEDLKVRKAIDFLVENR"
     misc_feature    complement(5545..5563)
                     /note="TFBS match to HgtR, Hydrogen-dependent regulator,
                     confidence: weak, score: 26.54"
                     /tool="antismash"
     gene            complement(5683..6690)
                     /gene="ddcA"
                     /gene_synonym="ysoA"
                     /locus_tag="EI692_RS12520"
                     /old_locus_tag="EI692_12605"
     CDS             complement(5683..6690)
                     /codon_start=1
                     /gene="ddcA"
                     /gene_synonym="ysoA"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010335186.1"
                     /locus_tag="EI692_RS12520"
                     /note="acts as an antagonist to the cell cycle checkpoint
                     enforcement protein YneA; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /old_locus_tag="EI692_12605"
                     /product="DNA damage checkpoint antagonist DdcA"
                     /protein_id="WP_111292155.1"
                     /transl_table=11
                     /translation="MKHDKKKDNVILFPGLKERLIEKGMAALKDKQYQEALHLFSEAKS
                     YDDDEESDIHLGMAICFLELGELQDAKRVCEKMLHEGYGHYFTVLQVYMTILIQLKEYE
                     EVKQTIEAVLEENHLPAESAEHFYKLLEFSRKMIDSPEEILDDDEDAGSEVNIDDMLKR
                     PEEQVQFIHSLKDRNITPHMGLLNTILQNPDGNPLVKSMILQLLADHDVAKPVHVTKFG
                     DSLTLIPSEAVKPEQMPLLQQVLRMLDDTLGNENPTLYQGVEELWRRHLFVLYPFLPKY
                     TDPSLWAAALHKVGYEMHGIEIELEELHLLYEFNERELREACTMLKDIEEISYL"
     gene            complement(6816..7415)
                     /gene="leuD"
                     /locus_tag="EI692_RS12525"
                     /old_locus_tag="EI692_12610"
     CDS             complement(6816..7415)
                     /EC_number="4.2.1.33"
                     /GO_component="GO:0009316 - 3-isopropylmalate dehydratase
                     complex [Evidence IEA]"
                     /GO_function="GO:0003861 - 3-isopropylmalate dehydratase
                     activity [Evidence IEA]"
                     /GO_process="GO:0009098 - L-leucine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="leuD"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_390703.1"
                     /locus_tag="EI692_RS12525"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EI692_12610"
                     /product="3-isopropylmalate dehydratase small subunit"
                     /protein_id="WP_024423183.1"
                     /transl_table=11
                     /translation="MEPLVTHKGKAAVLNRINVDTDQIIPKQFLKRIERTGYGRFAFFD
                     WRYLADGSPNPDFELNQPIYEGASILIAGENFGCGSSREHAPWALDDYGFKIVIAPSFA
                     DIFHQNCFKNGMLPIRLDYDVWKTFAASYENKGYEMTVDLEKQQIEDHEGNITPFQVDP
                     HWREMLLNGYDEISLTLLLEDDIQAFEEKRSSWLRA"
     gene            complement(7429..8844)
                     /gene="leuC"
                     /locus_tag="EI692_RS12530"
                     /old_locus_tag="EI692_12615"
     CDS             complement(7429..8844)
                     /EC_number="4.2.1.33"
                     /GO_component="GO:0009316 - 3-isopropylmalate dehydratase
                     complex [Evidence IEA]"
                     /GO_function="GO:0003861 - 3-isopropylmalate dehydratase
                     activity [Evidence IEA]"
                     /GO_process="GO:0009098 - L-leucine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="leuC"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003216723.1"
                     /locus_tag="EI692_RS12530"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EI692_12615"
                     /product="3-isopropylmalate dehydratase large subunit"
                     /protein_id="WP_048239029.1"
                     /transl_table=11
                     /translation="MPRTIIEKIWDQHVVKSGEGKPDLLYIDLHLVHEVTSPQAFEGLR
                     QKGRKVRRPQNTFATMDHNIPTVNRFVIKDEIAKKQVSALERNCAEFGVRLADLHSVDQ
                     GIVHVVGPELGLTLPGKTIVCGDSHTSTHGAFGALAFGIGTSEVEHVLSTQTLWQQRPK
                     TLEIRVDGKLQKGVTAKDVILAVIGAHGVKFGSGYVIEYTGEVFRNMTMDERMTVCNMS
                     IEAGARAGLIAPDEITFEYCRGRKYAPQGEDFEAAIKEWEELRTDPGATYDKTIVLDGN
                     KISPMVTWGINPGMVLPVDASIPGPEDFAQEDDQKEAIRAYEYMGVHPHQRIEDITIEH
                     VFIGSCTNSRMTDLRQAASMIEGQKVADHVRAIVVPGSQSVKLQAEEEGLHEIFLEAGF
                     EWRESGCSMCLSMNNDVVPEGERCASTSNRNFEGRQGKGARTHLVSPAMAAMAAIHGRF
                     VDVRKFNQEKTVV"
     gene            complement(8885..9982)
                     /gene="leuB"
                     /locus_tag="EI692_RS12535"
                     /old_locus_tag="EI692_12620"
     CDS             complement(8885..9982)
                     /EC_number="1.1.1.85"
                     /GO_function="GO:0003862 - 3-isopropylmalate dehydrogenase
                     activity [Evidence IEA]"
                     /GO_process="GO:0009098 - L-leucine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="leuB"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017358147.1"
                     /locus_tag="EI692_RS12535"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EI692_12620"
                     /product="3-isopropylmalate dehydrogenase"
                     /protein_id="WP_111292154.1"
                     /transl_table=11
                     /translation="MKKKIALLPGDGIGPEVVTSAVAVLQETAAQFRHEFEFETALIGG
                     IAIDEKNNPLPKETVDVCKSADAILLGAVGGPKWDQNPPELRPEKGLLAIRKQLDLFAN
                     IRPVKVFDSLSEASPLKQDHINGVDFVIVRELTGGLYFGEPSERYTDDEGKEAAVDTLL
                     YTKEEIVRVLKEAFDMALTRRKKVTSVDKANVLASSKLWRDAVEEVAAQYPEVEFEHML
                     VDNAAMQLIYKPAQFDVIVTENMFGDILSDEASMITGSLGMLPSASLSSTGLHLYEPIH
                     GSAPDIAGQNVANPLATILSAASLLRTSFALEEEAAAIEEAVEAVLASGKRTKDLAAKE
                     GTYQTTEEITNAVVDALKQRVQTIV"
     misc_feature    complement(9952..9968)
                     /note="TFBS match to NtrC, Nitrogen regulatory protein C,
                     confidence: weak, score: 20.93"
                     /tool="antismash"
     gene            complement(10001..11554)
                     /locus_tag="EI692_RS12540"
                     /old_locus_tag="EI692_12625"
     CDS             complement(10001..11554)
                     /EC_number="2.3.3.13"
                     /GO_function="GO:0003852 - 2-isopropylmalate synthase
                     activity [Evidence IEA]"
                     /GO_process="GO:0009098 - L-leucine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     betalactone: HMGL-like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1271: 2-isopropylmalate synthase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012010790.1"
                     /locus_tag="EI692_RS12540"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EI692_12625"
                     /product="2-isopropylmalate synthase"
                     /protein_id="WP_024423186.1"
                     /sec_met_domain="HMGL-like (E-value: 3.6e-95, bitscore:
                     316.3, seeds: 15, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRKINFFDTTLRDGEQSPGVNLNAQEKLIIAKQLERLGVNIIEAG
                     FPASSRGDFLGVQEIARTIKNCSVAGLARCVKGDIDAAWEALKDGVEPRLHVFIATSDI
                     HLKHKLKKTREEVVEQAVAMVKYAKERFPVVQWSAEDACRTDLAFLAEIVEKVIDAGAS
                     VINLPDTVGYLAPKEYGNIFKYMKEHVPNIDRVNLSAHCHDDLGMAVANSLAAIENGAD
                     QIETAVNGIGERAGNAALEEIAVALHIRKDFYQVESTIQLNEIKRTSDVVSKYSGMIVP
                     RNKAVVGNNAFAHESGIHQDGFLKEKTTYEIISPELVGVTTDVLVLGKHSGRHAFKDRM
                     KTLGFKLTEDEINKFFETFKNLTEKKKEITDDDLISIILEEKVADRKIGYEFESLQVHY
                     GTEQMPTATVSLKNQETQEVIQEAATGAGSVEAVYNTLERCMEERIHLLDYRIQSNGKG
                     RDALAEVYVTVSIEGKETAGRGVAQDVLEASAKAYVNAVNRHLIFKSNLIEIEKHHAIS
                     "
     gene            complement(11541..12569)
                     /gene="ilvC"
                     /locus_tag="EI692_RS12545"
                     /old_locus_tag="EI692_12630"
     CDS             complement(11541..12569)
                     /EC_number="1.1.1.86"
                     /codon_start=1
                     /gene="ilvC"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) 2-Hacid_dh_C"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_390707.1"
                     /locus_tag="EI692_RS12545"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EI692_12630"
                     /product="ketol-acid reductoisomerase"
                     /protein_id="WP_024423187.1"
                     /sec_met_domain="2-Hacid_dh_C (E-value: 2e-09, bitscore:
                     34.9, seeds: 135, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MVKVYYNGDIQENVLNGQKVAIIGYGSQGHAHALNLKESGVDVIV
                     GVRKGGSYTKAQEDGHQVFTVKEAAAQADVVMVLLPDEQQKKVYDEEIKDQLEAGNSLV
                     FAHGFNVHFHQIVPPSDVDVYLVAPKGPGHLVRRTYEQGAGVPALFAIYQDVSGQAKDK
                     ALAYAKAIGGARAGVLETTFKEETETDLFGEQAVLCGGLTSLVKAGFETLTEAGYQPEL
                     AYFECLHELKLIVDLMYEEGLEGMRYSISDTAQWGDFVSGPRVVDAKVKESMKAVLTDI
                     QNGTFAKEWIVENQVNRPRFNAINANENEHQIEIVGRKLREMMPFVKQGKKKEAVSVGA
                     EN"
     gene            complement(12589..13107)
                     /gene="ilvN"
                     /locus_tag="EI692_RS12550"
                     /old_locus_tag="EI692_12635"
     CDS             complement(12589..13107)
                     /EC_number="2.2.1.6"
                     /GO_component="GO:0005948 - acetolactate synthase complex
                     [Evidence IEA]"
                     /GO_function="GO:0003984 - acetolactate synthase activity
                     [Evidence IEA]"
                     /GO_process="GO:0009097 - isoleucine biosynthetic process
                     [Evidence IEA]"
                     /GO_process="GO:0009099 - valine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="ilvN"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_390708.2"
                     /locus_tag="EI692_RS12550"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EI692_12635"
                     /product="acetolactate synthase small subunit"
                     /protein_id="WP_007501584.1"
                     /transl_table=11
                     /translation="MKRIIVLTVLNRSGVLNRITGLFTKRHYNIESITVGHSEIQDVSR
                     ITFVVHVDQEKDIEQLTKQLNKQIDVLKVTDITNQSIVQRELALIKVVSAPASRMEITG
                     VIEPFRASIVDVSRESVVIQVTGESSKIEALIELLKPYGIKEVARTGTTAFARDNQQKP
                     QTNKTISIV"
     gene            complement(13104..14828)
                     /gene="ilvB"
                     /locus_tag="EI692_RS12555"
                     /old_locus_tag="EI692_12640"
     CDS             complement(13104..14828)
                     /GO_function="GO:0003984 - acetolactate synthase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="ilvB"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) TPP_enzyme_N"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) TPP_enzyme_C"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1055: pyruvate oxidase/decarboxylase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_390709.1"
                     /locus_tag="EI692_RS12555"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EI692_12640"
                     /product="acetolactate synthase large subunit"
                     /protein_id="WP_024427826.1"
                     /sec_met_domain="TPP_enzyme_N (E-value: 5e-54, bitscore:
                     180.3, seeds: 75, tool: rule-based-clusters)"
                     /sec_met_domain="TPP_enzyme_C (E-value: 2.6e-54, bitscore:
                     181.0, seeds: 323, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MGTNVQMETEKSKAPQTMNGALMLIEALKREKVEVIFGYPGGAVL
                     PIYDKIYNSGLFHVLPRHEQGAIHAAEGYARVSGKPGVVIATSGPGATNLVTGIADAMI
                     DSLPLVVFTGQVATSVIGSDAFQEADVLGITMPITKHSYQVRNPEELPGVIKEAFHIAT
                     TGRPGPVLIDIPKDVAGIEGTFEYDQPIDLPGYQPKVEPNYLQIRKLVEAVSRAKKPVI
                     LAGAGVLHGKASEELRQYVEQQQIPVAHTLLGLGGFPAKHPLFLGMAGMHGTYAANMAL
                     HQCDLLISIGARFDDRVTGNLNHFAKHAKVAHIDIDPAEIGKNIHTHIPVVGDSKLVLE
                     ELIKQDGKQADADEWKNQLDQWKEEYPLWYVENEAEGFKPQKLIEYIHQFTKGEAIVAT
                     DVGQHQMWAAQFYPFENADKWVTSGGLGTMGFGLPAAIGAQLADQEATVVAILGDGGFQ
                     MTLQELAVIRELNLPVKVIVLNNHCLGMVRQWQEIFYEERYSHSKFSEQPDFVKLSEAY
                     GIKGIRISSDEEAKEKLEEALTSREPVFIDVNVARDEKVFPMVAPGKGLHEMVGVKP"
     misc_binding    complement(14951..15198)
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
     misc_feature    15053..15063
                     /note="TFBS match to HypR, L-hydroxyproline utilization
                     repressor, confidence: weak, score: 18.94"
                     /tool="antismash"
     gene            complement(15207..16121)
                     /gene="ilvE"
                     /locus_tag="EI692_RS12560"
                     /old_locus_tag="EI692_12645"
     CDS             complement(15207..16121)
                     /EC_number="2.6.1.42"
                     /GO_function="GO:0004084 - branched-chain-amino-acid
                     transaminase activity [Evidence IEA]"
                     /GO_process="GO:0009082 - branched-chain amino acid
                     biosynthetic process [Evidence IEA]"
                     /NRPS_PKS="Domain: Aminotran_4 (47-281). E-value: 2.6e-48.
                     Score: 156.7. Matches aSDomain:
                     nrpspksdomains_EI692_RS12560_Aminotran_4.1"
                     /codon_start=1
                     /gene="ilvE"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003216381.1"
                     /locus_tag="EI692_RS12560"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EI692_12645"
                     /product="branched-chain-amino-acid transaminase"
                     /protein_id="WP_024427825.1"
                     /transl_table=11
                     /translation="MEDQKEQWIFLNDELVKKEDAKISVYDHGFLYGDGVFEGIRVYNG
                     NIFRMKEHLDRLYDSARSIMLNIPYSLEELTEKMIHTVERNGLKDAYIRLVVSRGAGDL
                     GLDPNNCGRANTVIIVEPLAIFPKHLYETGIDIVTVPTRRNRPDVLSPKVKSLNYLNNI
                     LVRIEAHMAGVSEALMLNDQGYVAEGSADNVFIYKKGKLYTPPGYIGALEGITRNAIME
                     IAEDLGYEVKEEPFTRHDVYTAEEVFLTGTAAEVIAVVKVDGRTIGEGKPGFHTNKLLE
                     QFRKRVVEEGEKVVFADENIHAS"
     aSDomain        complement(15279..15980)
                     /aSDomain="Aminotran_4"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_EI692_RS12560_Aminotran_4.1"
                     /evalue="2.60E-48"
                     /label="EI692_RS12560_Aminotran_4.1"
                     /locus_tag="EI692_RS12560"
                     /protein_end="281"
                     /protein_start="47"
                     /score="156.7"
                     /tool="antismash"
                     /translation="FRMKEHLDRLYDSARSIMLNIPYSLEELTEKMIHTVERNGLKDAY
                     IRLVVSRGAGDLGLDPNNCGRANTVIIVEPLAIFPKHLYETGIDIVTVPTRRNRPDVLS
                     PKVKSLNYLNNILVRIEAHMAGVSEALMLNDQGYVAEGSADNVFIYKKGKLYTPPGYIG
                     ALEGITRNAIMEIAEDLGYEVKEEPFTRHDVYTAEEVFLTGTAAEVIAVVKVDGRTIGE
                     GKPGFHTNKLLE"
     misc_feature    16161..16175
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence:
                     medium, score: 23.06"
                     /tool="antismash"
     misc_feature    16357..16373
                     /note="TFBS match to HexR, Glucose-responsive regulator,
                     confidence: weak, score: 23.5"
                     /tool="antismash"
     misc_feature    16384..16395
                     /note="TFBS match to AfsR, Pleiotropic regulatory for
                     antibiotic production, confidence: medium, score: 19.28"
                     /tool="antismash"
     misc_feature    complement(16494..16505)
                     /note="TFBS match to CcpA, Catabolite control protein A,
                     confidence: medium, score: 17.85"
                     /tool="antismash"
     gene            16555..17598
                     /locus_tag="EI692_RS12565"
                     /old_locus_tag="EI692_12650"
     CDS             16555..17598
                     /EC_number="3.1.1.-"
                     /GO_function="GO:0052689 - carboxylic ester hydrolase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017358149.1"
                     /locus_tag="EI692_RS12565"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EI692_12650"
                     /product="lactonase family protein"
                     /protein_id="WP_249856340.1"
                     /transl_table=11
                     /translation="MANIRGYIGTYTKGDSKGVYTFTLNTDKQQIEQVEVAAELENPTY
                     LTVSEDQKFVYAVVKKGSQGGLAAYQIDSTTGRLHFINQELADGASPCHVSVDSQTKTA
                     YTANYHKGSAEMYEIDAENGSVIRTLSQAQHEGTGPNEDRQEKPHTHFMGLTPDEQFAV
                     AVDLGTDGIYTYKKEDGKLELSHTFETKPGSGPRHITFHPTKPVAYVMTELSSEVIVLR
                     YFEDGHFEEIQTIATIPSDFTENNQGSAIHVSSDGQFVYAGNRGHDSIAIFKADADGQL
                     SLVEIASSEGNWPRDFVLDPTEEFLVGSNQESSNLVLYKRDKETGRLTVLQSDITVPHP
                     VCVKFLG"
     gene            complement(17828..18247)
                     /locus_tag="EI692_RS12570"
                     /old_locus_tag="EI692_12655"
     CDS             complement(17828..18247)
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012010795.1"
                     /locus_tag="EI692_RS12570"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EI692_12655"
                     /product="YkvA family protein"
                     /protein_id="WP_034279788.1"
                     /transl_table=11
                     /translation="MNRSEKKELLKRSKKHFNDHAFWEKLKKTAQKAGVSLVYAVLLLY
                     YTLQKPEVPVKAKTLIIGALGYFILPLDLIPDTLIGVGYTDDLGAITFALLQVAMYIDD
                     DVKGKAKDRLSKWFGEKTDTSLIDQKLEDGGMPSA"
     gene            complement(18343..19509)
                     /gene="dltD"
                     /locus_tag="EI692_RS12575"
                     /old_locus_tag="EI692_12660"
     CDS             complement(18343..19509)
                     /GO_process="GO:0070394 - lipoteichoic acid metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /gene="dltD"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017358151.1"
                     /locus_tag="EI692_RS12575"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EI692_12660"
                     /product="D-alanyl-lipoteichoic acid biosynthesis protein
                     DltD"
                     /protein_id="WP_095409221.1"
                     /transl_table=11
                     /translation="MKKRFFGPLILAAVLFIGVLLVPNAWLSHLIPKDKLQKSATELDP
                     GMFQGLYLQDEMLKDPTYLPIYGSSELSRFDPYHPSNFFHENPQGFTPYLIGKGGSQSL
                     IHAMNFAAHMDELKGKKLVFIVSPQWFVKWGSDENHFAPNYSALQALNLAYNKEIDPTV
                     KKELIKRIMKFKAVKNDMVITELFKAELSGNKFAYGAISPIAKMYYGMLQKKDMYYTIG
                     SGPERKLQPSPSVKGKTWAELEKEASIFGAKRAGDNPFYINQKLFDRKLKPIMKKMKDS
                     REGHSYAESPEYKDFQIMLDILKQAGAKPLFVTIPVNGKWYDYTGFPKEGRTGYYEKIN
                     RQIRDNGYEVADLTKHEYDPYFFKDTIHVSYKGWVYIDKAIEKFYKEQ"
     gene            complement(19509..19745)
                     /gene="dltC"
                     /locus_tag="EI692_RS12580"
                     /old_locus_tag="EI692_12665"
     CDS             complement(19509..19745)
                     /EC_number="6.1.1.13"
                     /GO_function="GO:0047473 - D-alanine [D-alanyl carrier
                     protein] ligase activity [Evidence IEA]"
                     /GO_process="GO:0019350 - teichoic acid biosynthetic
                     process [Evidence IEA]"
                     /NRPS_PKS="Domain: PP-binding (5-71). E-value: 4.6e-10.
                     Score: 31.7. Matches aSDomain:
                     nrpspksdomains_EI692_RS12580_PP-binding.1"
                     /codon_start=1
                     /gene="dltC"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003186284.1"
                     /locus_tag="EI692_RS12580"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EI692_12665"
                     /product="D-alanine--poly(phosphoribitol) ligase subunit 2"
                     /protein_id="WP_024423191.1"
                     /sec_met_domain="PP-binding (E-value: 2.9e-09, bitscore:
                     35.1, seeds: 164, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEFKNQVYGIIAEVCQDDVVKENPEIAIFEEGLLDSFGTVELLMA
                     IESQLGITVPITEFDRDVWDTPNHIAEQLAEMK"
     aSDomain        complement(19533..19730)
                     /aSDomain="PP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_EI692_RS12580_PP-binding.1"
                     /evalue="4.60E-10"
                     /label="EI692_RS12580_PP-binding.1"
                     /locus_tag="EI692_RS12580"
                     /protein_end="71"
                     /protein_start="5"
                     /score="31.7"
                     /tool="antismash"
                     /translation="QVYGIIAEVCQDDVVKENPEIAIFEEGLLDSFGTVELLMAIESQL
                     GITVPITEFDRDVWDTPNHIA"
     gene            complement(19767..20951)
                     /gene="dltB"
                     /locus_tag="EI692_RS12585"
                     /old_locus_tag="EI692_12670"
     CDS             complement(19767..20951)
                     /GO_function="GO:0016746 - acyltransferase activity
                     [Evidence IEA]"
                     /GO_process="GO:0070395 - lipoteichoic acid biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /gene="dltB"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017358153.1"
                     /locus_tag="EI692_RS12585"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EI692_12670"
                     /product="D-alanyl-lipoteichoic acid biosynthesis protein
                     DltB"
                     /protein_id="WP_095409222.1"
                     /transl_table=11
                     /translation="MIPFSSFFFFILIGILLLPTIILGLRGKRMQGYNMFATVVALALI
                     FSKDAHGALLLFLFTVWQVLIIRLYLAYRLKANQASVFYTAVVASILPLVLSKILPFFL
                     THQPHQPPPMNWLSFLGISYLTFKGVQLIIETRDGLIKKKIPIHRLVYFIVFFPTISSG
                     PIDRYRRFEKDMDTPPEKEAYSDLLYAGIHKIFIGFLYKFIIGYLIHTYILMNIHHISS
                     SHFVQQLTYMYAYSMYLFFDFAGYTAFAVGVSYIMGIKSPENFNKPFISRNIKDFWNRW
                     HMSLSFWFRDYVFMRFVFFMTKKKWIKNRMAVSNIGYFILFLLMGAWHGLALQYIIYGL
                     YHAVVMSGYNLFEKWNKKHKWWPDNKVTMVVSIIITFHVICFGFYIFSGKPFHH"
     gene            complement(20948..22453)
                     /gene="dltA"
                     /locus_tag="EI692_RS12590"
                     /old_locus_tag="EI692_12675"
     CDS             complement(20948..22453)
                     /EC_number="6.1.1.13"
                     /GO_function="GO:0047473 - D-alanine [D-alanyl carrier
                     protein] ligase activity [Evidence IEA]"
                     /GO_process="GO:0019350 - teichoic acid biosynthetic
                     process [Evidence IEA]"
                     /NRPS_PKS="Domain: AMP-binding (11-401). E-value: 2.5e-89.
                     Score: 291.6. Matches aSDomain:
                     nrpspksdomains_EI692_RS12590_AMP-binding.1"
                     /codon_start=1
                     /gene="dltA"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     betalactone: AMP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1002: AMP-dependent synthetase and ligase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003186280.1"
                     /locus_tag="EI692_RS12590"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EI692_12675"
                     /product="D-alanine--poly(phosphoribitol) ligase subunit
                     DltA"
                     /protein_id="WP_249856341.1"
                     /sec_met_domain="AMP-binding (E-value: 2.3e-93, bitscore:
                     310.8, seeds: 400, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKLLQTIHEYQQTKPTQPAFVSQHATITYDELWYLSDQMAGAIDA
                     VATGSEPVIVYGHMEPEMLISFLGSVKSGRPYIPVDISIPVERIVSIIESSKASLLICA
                     NEQNVLDVEEHIEVKSAASLLALEKEAPPSTQWVQQDDVFYIIYTSGSTGKPKGVQVTA
                     NNLESFTEWMCRDFPIGEGRTFLNQAPFSFDLSVMDLYPALQSGGTLYCLVKDFVNKPK
                     DMFAALGQSDVEVWTSTPSFVQMCLMDPSFTGELLPELKVFLFCGEALPVAVASALLER
                     FPKAQVFNTYGPTEATVAITSIEVTQEILDQHDSLPVGYAKPDTDIVILDEEGKTLPDG
                     EKGEIVIVGPSVTRGYLGEQALTDKVFFEYEGRPAYRTGDAGVAHDGLITCHGRLDYQI
                     KLHGYRMELEEIEYHVSETTYVNACVIVPFQPNGHVEYLIAAIVPAAHSFEKEYRLTSA
                     IKKEMADSLPAYMIPRKFVYLEQLYMTPNGKVDRKRIAKEVLL"
     CDS_motif       complement(21194..21217)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_EI692_RS12590_0005"
                     /evalue="9.70E+01"
                     /label="NRPS-A_a5"
                     /locus_tag="EI692_RS12590"
                     /protein_end="420"
                     /protein_start="412"
                     /score="-2.5"
                     /tool="antismash"
                     /translation="YHVSETTY"
     CDS_motif       complement(21218..21283)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_EI692_RS12590_0004"
                     /evalue="5.20E-08"
                     /label="NRPS-A_a8"
                     /locus_tag="EI692_RS12590"
                     /protein_end="412"
                     /protein_start="390"
                     /score="25.2"
                     /tool="antismash"
                     /translation="CHGRLDYQIKLHGYRMELEEIE"
     aSDomain        complement(21251..22420)
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_EI692_RS12590_AMP-binding.1"
                     /evalue="2.50E-89"
                     /label="EI692_RS12590_AMP-binding.1"
                     /locus_tag="EI692_RS12590"
                     /protein_end="401"
                     /protein_start="11"
                     /score="291.6"
                     /specificity="substrate consensus: Ala"
                     /tool="antismash"
                     /translation="QTKPTQPAFVSQHATITYDELWYLSDQMAGAIDAVATGSEPVIVY
                     GHMEPEMLISFLGSVKSGRPYIPVDISIPVERIVSIIESSKASLLICANEQNVLDVEEH
                     IEVKSAASLLALEKEAPPSTQWVQQDDVFYIIYTSGSTGKPKGVQVTANNLESFTEWMC
                     RDFPIGEGRTFLNQAPFSFDLSVMDLYPALQSGGTLYCLVKDFVNKPKDMFAALGQSDV
                     EVWTSTPSFVQMCLMDPSFTGELLPELKVFLFCGEALPVAVASALLERFPKAQVFNTYG
                     PTEATVAITSIEVTQEILDQHDSLPVGYAKPDTDIVILDEEGKTLPDGEKGEIVIVGPS
                     VTRGYLGEQALTDKVFFEYEGRPAYRTGDAGVAHDGLITCHGRLDYQIKL"
     CDS_motif       complement(21353..21442)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_EI692_RS12590_0003"
                     /evalue="5.10E-10"
                     /label="NRPS-A_a6"
                     /locus_tag="EI692_RS12590"
                     /protein_end="367"
                     /protein_start="337"
                     /score="31.6"
                     /tool="antismash"
                     /translation="PDGEKGEIVIVGPSVTRGYLGEQALTDKVF"
     CDS_motif       complement(21557..21583)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_EI692_RS12590_0002"
                     /evalue="5.90E-03"
                     /label="NRPS-A_a5"
                     /locus_tag="EI692_RS12590"
                     /protein_end="299"
                     /protein_start="290"
                     /score="9.4"
                     /tool="antismash"
                     /translation="YGPTEATVA"
     CDS_motif       complement(21968..22021)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_EI692_RS12590_0001"
                     /evalue="2.50E-09"
                     /label="NRPS-A_a3"
                     /locus_tag="EI692_RS12590"
                     /protein_end="162"
                     /protein_start="144"
                     /score="29.2"
                     /tool="antismash"
                     /translation="YIIYTSGSTGKPKGVQVT"
     gene            complement(22468..22617)
                     /locus_tag="EI692_RS12595"
                     /old_locus_tag="EI692_12680"
     CDS             complement(22468..22617)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003227330.1"
                     /locus_tag="EI692_RS12595"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EI692_12680"
                     /product="teichoic acid D-Ala incorporation-associated
                     protein DltX"
                     /protein_id="WP_024427820.1"
                     /transl_table=11
                     /translation="MNMLFKKLSENKSVKWIGYTSFYLLILLLLFFIYGFHTANTGSFI
                     YNDF"
     gene            complement(22870..24186)
                     /locus_tag="EI692_RS12600"
                     /old_locus_tag="EI692_12685"
     CDS             complement(22870..24186)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017358155.1"
                     /locus_tag="EI692_RS12600"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EI692_12685"
                     /product="kelch repeat-containing protein"
                     /protein_id="WP_249856342.1"
                     /transl_table=11
                     /translation="MKKWFFIFVLLISALIYPLQSIKAEKADILEWEKRAELPAARVGA
                     VSEVYDGKIYVIGGIGSGKANSNTTYVYDPKLDKWSEKASMKTGRMGAASAIVGDHIYV
                     MGGRTDQGFSNSVEVYNIKMDKWEEAEDLPFELKISAFDLYAGAIDNKIYVLGYNKPLK
                     HEKYSSNTYSYDIKTKEWTKKKKFEKDAPAGNAVVIKNKLYVLSGQATFEYDPSIDQWT
                     SVGSGGIGRYYSALNFEDYIIRTGGVSKVTLYDKQTKTSRTVPNSSAPYRMGHVSAIID
                     DTLYVIGGIPQSNDAPNYARDDFKSNLSISLKSLKNSDTTAPPGDKDPDTATPPKDGTT
                     NPGDKDQEPTTPPKDDTTNEDGDALLIITMVNGLQKEYDLSMKEVNAFLSWYKKRDAGK
                     GPGFYEIDEHDNNKGPFESKKDYVVFNNILMFEVNKYKK"
     misc_feature    complement(24398..24407)
                     /note="TFBS match to ToxT, Regulator of MSHA biosynthesis,
                     confidence: strong, score: 18.57"
                     /tool="antismash"
     gene            complement(24427..24612)
                     /locus_tag="EI692_RS19615"
                     /old_locus_tag="EI692_12690"
     CDS             complement(24427..24612)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF025391.4"
                     /locus_tag="EI692_RS19615"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EI692_12690"
                     /product="DUF4241 domain-containing protein"
                     /protein_id="WP_269196468.1"
                     /transl_table=11
                     /translation="MAEALEQNYKHTWDWLVTRFHDKVDIAVFTTVFGDGMYPSYWGLD
                     ENGELTCLVTDFLIMG"
     gene            25292..26272
                     /locus_tag="EI692_RS12610"
                     /old_locus_tag="EI692_12705"
     CDS             25292..26272
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) adh_short_C2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1001: short-chain dehydrogenase/reductase SDR"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012010806.1"
                     /locus_tag="EI692_RS12610"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EI692_12705"
                     /product="SDR family oxidoreductase"
                     /protein_id="WP_058838314.1"
                     /sec_met_domain="adh_short_C2 (E-value: 1.3e-32, bitscore:
                     111.6, seeds: 47, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTQESDERKLQQIKQMQQMFLEKMKTQPYPMYPNYGKITRYEEIP
                     INLPEQRQLRHPGVEGLMVPLPIIENTNYKGSGKLAGKVALITGGDSGIGAAVAIAFAK
                     ESADVAIAYLDEHEDANRTKARIEELGQRCLLMPGDLRDKRQCITIVEKTVKTFGRLDV
                     LCNHVGIQFQQPSLLDITDEQFDDTFKVNIYSHFYTTRAALPYLKPGSSIIGTSSVVTY
                     VGEQQMIDYTATKGAIVGWTRALAKNVVKQGIRVNAVAPGRIWTPLIAASFSSDQVAVY
                     GAFNPMERVAHPFELAPTFVYLASDDSRFVTGQVLHVDGGESTHS"
     tRNA            complement(26671..26744)
                     /anticodon=(pos:complement(2445896..2445898),aa:Arg,
                     seq:tct)
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /locus_tag="EI692_RS12615"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /old_locus_tag="EI692_12710"
                     /product="tRNA-Arg"
     gene            complement(26671..26744)
                     /locus_tag="EI692_RS12615"
                     /old_locus_tag="EI692_12710"
     gene            complement(26865..27389)
                     /locus_tag="EI692_RS12620"
                     /old_locus_tag="EI692_12715"
     CDS             complement(26865..27389)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Metallophos_2"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007501597.1"
                     /locus_tag="EI692_RS12620"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EI692_12715"
                     /product="metallophosphoesterase"
                     /protein_id="WP_197198330.1"
                     /sec_met_domain="Metallophos_2 (E-value: 2.7e-31, bitscore:
                     106.6, seeds: 57, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKILIISDSHGLTDELQTIAKRHAAEVDMMIHCGDSELETNHPAL
                     EGYKVVKGNCDFMGDFEEELLLPLDGGGKLFLTHGHLHGIKQSLLQVYYRAEELGADII
                     CFGHSHIPGSELLRGKLLINPGSVHLPRVRKERSYAILTLDGSEANVQFFTDEGQVIKD
                     LENTVTLEGIS"
     gene            complement(27404..28006)
                     /locus_tag="EI692_RS12625"
                     /old_locus_tag="EI692_12720"
     CDS             complement(27404..28006)
                     /EC_number="3.6.1.66"
                     /GO_function="GO:0047429 - nucleoside triphosphate
                     diphosphatase activity [Evidence IEA]"
                     /GO_process="GO:0009143 - nucleoside triphosphate catabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007501598.1"
                     /locus_tag="EI692_RS12625"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EI692_12720"
                     /product="XTP/dITP diphosphatase"
                     /protein_id="WP_095409231.1"
                     /transl_table=11
                     /translation="MIRMKTAIIATHNAGKAKEFKAILEPKGFTVKTLADIGFTEEIEE
                     TGQTFEENAIIKAEAIQAKAGEMVIADDSGLSIDYLGGKPGVYSARYAGEHKDDAENVE
                     KVLSELQGIEKEDRTARFRCALAVSIPGKETKTVEGSVEGFIAEEPIGENGFGYDPIFI
                     VKDKDQTMAELSPEEKNKISHRAVALQKLSSLLDANE"
     gene            complement(28017..28745)
                     /gene="rph"
                     /locus_tag="EI692_RS12630"
                     /old_locus_tag="EI692_12725"
     CDS             complement(28017..28745)
                     /EC_number="2.7.7.56"
                     /GO_function="GO:0000049 - tRNA binding [Evidence IEA]"
                     /GO_function="GO:0009022 - tRNA nucleotidyltransferase
                     activity [Evidence IEA]"
                     /GO_process="GO:0008033 - tRNA processing [Evidence IEA]"
                     /codon_start=1
                     /gene="rph"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017358165.1"
                     /locus_tag="EI692_RS12630"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EI692_12725"
                     /product="ribonuclease PH"
                     /protein_id="WP_024427165.1"
                     /transl_table=11
                     /translation="MRLDERQYDELRKIEIEAGYITHPEGSVLISAGNTKVICNASIED
                     RVPPFLRGEGKGWITAEYSMLPRATAQRTIRESSKGKVTGRTMEIQRLIGRALRAVVDL
                     EKLGERTIWIDCDVIQADGGTRTASITGAFVAMTLAIQKLRAEGVIKENPITDYLAAIS
                     VGIDSQQGLLLDLNYEEDSSAEVDMNVIMTGAGRFVELQGTGEEATFSREQLNGLLDLA
                     EKGIKELIEKQKAVTGEVIE"
     gene            complement(28897..29958)
                     /locus_tag="EI692_RS12635"
                     /old_locus_tag="EI692_12730"
     CDS             complement(28897..29958)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003216461.1"
                     /locus_tag="EI692_RS12635"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EI692_12730"
                     /product="GerMN domain-containing protein"
                     /protein_id="WP_048239038.1"
                     /transl_table=11
                     /translation="MLKKGSTAAVTCIASAMLLSGCGLFQTDQAKTEIDPPQNVTYVKE
                     NKEDKQTAKEGKEEKQADTVMRELYLIDKNGYVVSQSIPLPKNEGSAKQTLEYLVDGGP
                     ISNLMPNGFRAVLPADTSVSVDIKDGTAVVDFSNEFKNYKKEDEQRILQSVTWTLTQFD
                     SIAKVKLKMNGHELKEMPVNGTPISDDLSREDGINIQHEAAADMTSTKPVTVYYLAESD
                     EQTYYVPVTTRAPKDEDDPITAAIDELVSGPSKKSHLLTDFDQDVKLNDVPKVKDGHVT
                     LDFNESIFGSADEKKKVISQKVLDSIVLTLTELPDVKSVSVKVNGKAELVNEKGAELTK
                     PVSRPEQVNTGSF"
     misc_feature    complement(30014..30027)
                     /note="TFBS match to CatR, H2O2-responsive repressor,
                     confidence: medium, score: 20.3"
                     /tool="antismash"
     gene            complement(30060..30875)
                     /gene="racE"
                     /locus_tag="EI692_RS12640"
                     /old_locus_tag="EI692_12735"
     CDS             complement(30060..30875)
                     /EC_number="5.1.1.3"
                     /GO_function="GO:0008881 - glutamate racemase activity
                     [Evidence IEA]"
                     /GO_process="GO:0008152 - metabolic process [Evidence IEA]"
                     /codon_start=1
                     /gene="racE"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003216646.1"
                     /locus_tag="EI692_RS12640"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EI692_12735"
                     /product="glutamate racemase"
                     /protein_id="WP_034279765.1"
                     /transl_table=11
                     /translation="MDQPIGVIDSGVGGLTVAKEIMRQLPKEKIIYVGDTKRCPYGPRK
                     EEEVLQYTWEMAHYLLKHHHIKMLVIACNTATAIALDEIKATLDIPVIGVIQPGARTAI
                     KVTNNQHIGVIGTVNTIKSEAYKEALLSLKAGLTVQSLACPLLVPFVESGTFLDQTAEA
                     VVKDSLEPMKETGIDTLILGCTHYPILKEPIQRFMGSDVSIISSGDETAREASTILSYK
                     GLLNTSKEAPVHTFYTTGQQQNFQNIARDWFGYLPGKVETVSLEHIYQQ"
     gene            complement(30886..31326)
                     /locus_tag="EI692_RS12645"
                     /old_locus_tag="EI692_12740"
     CDS             complement(30886..31326)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1135: MarR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003216546.1"
                     /locus_tag="EI692_RS12645"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EI692_12740"
                     /product="MarR family transcriptional regulator"
                     /protein_id="WP_024423206.1"
                     /transl_table=11
                     /translation="METNESGHVAEIEKSLRHIAAIIKQKGREILNQYTITPPQFIGLQ
                     WLYEFGDMTIGELSQKMYLACSTTTDLIDRMEKSELVERVKDPSDRRVVRIHLLPEGER
                     IIQEVIAKRQEYVSELLGAFSEEEAIVFNQSLTKLQQQMKRK"
     gene            complement(31476..31700)
                     /gene="gerE"
                     /locus_tag="EI692_RS12650"
                     /old_locus_tag="EI692_12745"
     CDS             complement(31476..31700)
                     /codon_start=1
                     /gene="gerE"
                     /gene_functions="regulatory (smcogs) SMCOG1197:
                     autoinducer-binding transcriptional regulator,"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_390719.2"
                     /locus_tag="EI692_RS12650"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EI692_12745"
                     /product="spore germination transcription factor GerE"
                     /protein_id="WP_003184172.1"
                     /transl_table=11
                     /translation="MKEKEFQSKPLLTKREREVFELLVQDKTTKEIASELFISEKTVRN
                     HISNAMQKLGVKGRSQAVVELLRMGELEL"
     misc_feature    complement(31679..31697)
                     /note="TFBS match to FuR_variant_2, Ferric Uptake
                     Regulator, confidence: weak, score: 22.57"
                     /tool="antismash"
ORIGIN
        1 taatattctt tttgtgttcg ttccattgaa cgtttgacgc gctggccaat tttcttttca
       61 atttccagca cttctttttc attgtgaatt aagctgatga cacgattcag acgttttttg
      121 acatctactg tttccagcac ttcttgtttg tcttttaatt tgagcggcaa gtgagaagcg
      181 acgatatctg ccattctccc tggttcctca atatccgtca ccgttgcata tgtttcagct
      241 gagatttttt ttgaaatttt tatgtactga tcaaagtgat ctaacaaagt gcgcatgagt
      301 gcttctgctt ctgcgtcctt taattcttct tctgtcaatt ctttaatatc gacggacgta
      361 tagtcctcaa gctccacgta tgattcgatc tgcgctcgat ttaaaccttc aacgagtaca
      421 cgaatcgttc cattcggcag cttcagcatt tgtttaattt ttgtgtaggt gccgactttg
      481 aaaatttcct cttcacctgg ttcatctatt gaaatttccc gctgtgttgc tagaaaaatc
      541 atatgatcgt tcatcatcgc ctgttctaat gcttgaacag acttctcgcg tccaacgtcc
      601 aaatgcaaga ccattgttgg ataaacaagc aagcctcgca atggaaggag cggaacattc
      661 tttttgattt catctgccat gttgattgac acctccgtca ctagtatgaa tcattataat
      721 atacctgttt cagtcttgta caatgtaaaa gacttaagaa atgatgatct taccgtagta
      781 taccctttct ttttatcttg aaaaagaaaa aaagatctat ttcactaaaa aatccccata
      841 tgtgatgggg attaaacaga ttttcttttc atttcgtctt ctagtccatc tttcttctcg
      901 tctggcggat tgaccagaca ctgatccagc acctcttgga agtgcttcac aggcacaatg
      961 gtgacccctt caatctcctt taagatcgac tgctgattgt cataaggaat aatgacggtt
     1021 gtggcaccag cctgcttcgc tgccttaatc ttcggtatca caccaccgat tggcttcacc
     1081 tggccctgca atccgatttc acccgtcatg gctgtcagat gatcaatcgg aatttgatgt
     1141 atggctgaga agattgcggt cgccatggca atcccagcag acggtccatc aattggggca
     1201 ccgcctggaa aattaatatg gatgtcatat tcatttgtcc gaatacctaa atttcgaagc
     1261 accgttaata cattttcaac tgaccctttg gccatacttt ttcgtcgaat agatttcgac
     1321 tgattgccaa tgctttcttc ttctgcaatg cctgtaatgt tgatacttcc cttttcaagc
     1381 gccttacaga tattcacttc aatctcaagc agggcaccgc tgtttggtcc ataaacagcc
     1441 agtccattga cgacccccac ttttggcttt tctggtactt tttgttcata tcttggtgtc
     1501 agctggcttg aatgaataac ccattctaca tcttcaatcg tgatgtcttt tcggttttcc
     1561 gtcaccgcca taccagcggc aatctgcacc atgttgaccg cttcacgtcc atttttcaca
     1621 taggaggtta acaagttcag cccttcatca cttaattcct tttcaatttt ttggacagcc
     1681 ttagcagcga cgattttcag ttcatgctgg tcaaggtctt taaagaaaat ttctaaacat
     1741 ctggatcgaa tcgctggcgg aatttcttca ggtgttcttg tcgtcgcacc aatcaatcga
     1801 aaatcagccg gaagcccatt ttgaaaaata tcatgaatgt gattcggaat ttgagtgttt
     1861 tcctcactgt agtaagcact gtctaaaaat actttccgat cttccagcac tttgagcatt
     1921 ttgttcattt ggatcggatg cagttcacca atttcatcga taaacagaac cccgccatga
     1981 gcatgcgtaa cggctccttg ttttggctgc ggaatgcctg cctgtcccat cgctcccgcc
     2041 ccttggtaaa tcgggtcatg cacggagcca atgagtgggt ctgcaatgcc acgttcatcg
     2101 aatcttgcgg ttgtggcatc gagctccaca aataccgcat ctttcttaaa cggtgaatca
     2161 gcatgacgtt tcgcttcttc cataacaaga cgggctgcgg ctgtttttcc cacccccggt
     2221 ggtccgtaga caatgacatg ctgaggattc ggtccgcaca gcgctgcttt tagagcacga
     2281 atgccatctt cctgccctac aatatcttga aatccctttg gccggactct ctctgataaa
     2341 ggctcactca gcttgattga ccgcatcttt ctgagtgctt ccatttcttt ctttgattct
     2401 ttgtctatcg tcaccttttg tgtgcgctga tttcgcagta agttccaaaa gtacagcccg
     2461 atgacgatac caaagaacag ctgtatgaat aatacgattc ctgtccagct caatcggtgc
     2521 tccctccttc atctatctta tgtattggtt tctgtctgct agtatttcct agagctggac
     2581 ggaataaaca cgtcttccac gataaataaa aaactcctga atctaaatga ttcaggagtg
     2641 ataacttctc ttatgcagat gtttttgtat ctttattaac gactgtgcca tcttttaaca
     2701 caagacgcgg cggctcacca tcagcaaccg ttgcaccagt gatgacacat ttttcaatat
     2761 catcacgaga tggaaggtca aacatgacat caagcatgat gccttcaatg attgagcgaa
     2821 gaccacgagc tcctgtttta cgctcaattg cctttttcgc aatttcgcta agagcatctt
     2881 cttcaaattc aagctctaca tcgtcaagct caagcatttt tgtatattgc ttaacaagcg
     2941 catttttagg cttcgtcaag atttctacaa gtgctttttc atctaacggc tctaggcttg
     3001 caataaccgg tagacgaccg atgaattctg gaattaaacc gaagcgaagc aagtcttctg
     3061 gcagtacctt tgatagaagg acttcttttt caagatcttc gactttattt tccgcaccga
     3121 atccaatgac tttttgacct aagcggcgtt tgatgatttg ctcaatcccg tcaaaggctc
     3181 ctccacaaat gaagaggatg ttcgtcgtat caatttgaat gaattcttga tgtgggtgct
     3241 tacgtccacc ttgaggcggt acactagcga ctgttccttc aagaattttc aaaagggctt
     3301 gctggacgcc ttccccagat acatcgcgag tgatagaagg gttttctgat tttcttgcta
     3361 ctttatcgat ctcatcgatg tagataatgc ctttttccgc tttttctaca tcataatccg
     3421 ctgcctggat cagctttagt aaaatattct ctacgtcttc accaacataa cctgcttcag
     3481 ttaatgatgt tgcatctgcg atcgcaaatg gaacatttaa aatacgagca agtgtttgag
     3541 caagtaatgt tttaccgctt cctgttggtc caatcataga aatattactt ttcgaaagct
     3601 caacatcatc aatcttgctg ttggaattaa tccgtttgta atggttatac accgctacag
     3661 ctaaggattt tttcgcattg tcttgtccga tgacatattc atcaagaatc tcccgaattt
     3721 catgaggctt cggaacatcc ttgaattcaa cttcttcctc agtgccgagc tcttcttcaa
     3781 ctatttccgt gcaaagctcg atacattcat cacatatata tacgccaggt cctgcgacca
     3841 gtttacgcac ttgatcttgc gtttttccgc aaaacgagca ttttaattga cctttttcct
     3901 cgttgaattt aaacattctt tcacccctta ttcttcttca cttgcctgta gctaacagtc
     3961 agctaccttt ctgggtccag tatgtatgca ttttaccata ctttcctaaa agacggtaac
     4021 gatgtgtttc taacactgca cattgagata tgtatgacag aaagatgcga cttacactat
     4081 cgtttccaaa agaagcgatg ataagtcaaa aattgtacaa aacaaggcac gagtcactcg
     4141 cgccctgttt tattattatg caccatatta acggttttct acaagaaaat caattgcttt
     4201 acgaactttt agatcttctt tcattgcttc agtagatccg atcgcttgtt tgatgttttc
     4261 aattggcatg ttgtatgctt cagccatttt tgaaagttct tcttccactt cttcgtcaga
     4321 cacttgtaag ttttctgcag cagcaattgc ttcaagtgtt aggttagatt taacgcgttt
     4381 agcagcatct tctttcattt gctctttcag cgcattttca tcttgtccag agaattggaa
     4441 gtaaagctca aggttcattc cttgcatttg aagacgttgt tcgaattctt tcatcatgcg
     4501 gtctagctct gtgtcaacca tcgcttgtgg gatgtcaact tccgcatttt cagaagcttt
     4561 cgcaactaac tcttcacgaa gttttccttc tgcttcgttt tcttttgctt cttcaagacg
     4621 tttcttcgtt ttttcagtta attcagcaag cgtttctact tcttcatcaa catctttagc
     4681 gaactcatcg tcaagtgctg gaagttcttt tgctttgatt tcatgaattt tcactttgaa
     4741 tacagctggt ttacctgcaa ggtcttcagc atgatattct tctgggaatg taacttctac
     4801 gtctttttca gcgccagctt caagaccaac taattgctct tcgaaaccag ggatgaatga
     4861 accagaacca acttcaagag agtagttctc agcttttccg ccttcgaatg cttctccatc
     4921 aacgaatcct tcgaaatcaa gaacaactgt atcgccgttt tcgattgcgc cttcttcttt
     4981 gacaacaagc tcagcttgac ggttttgcat gccttttagc tcttcttgta catcttcatc
     5041 agtgacagct gtgtcgtctt tttctacgtt aagacctttg tagtcaccaa gttttacttc
     5101 aggcttcact gttacttttg cagtgaagat taagttttcg cctttttcga ttttctcaac
     5161 atcgatttca gggcggtcaa ctggctcgat accagcttcg tcgattgctt ttggatattc
     5221 aactggaaga agaatatcta atgcatcttg ataaagagat tctacaccaa aacgttgctc
     5281 gaaaagacca cgtggtactt tccctttacg gaatccaggg attgatactt gcttaaccac
     5341 tttcttaaat gcatcatcaa gtgctttgtt aaatgtttca gcgtcaactt ctacagttag
     5401 aacgccttcg ttaccttctt gtttttccca ttttactgac atgtgtgttt ccctccaaaa
     5461 atctattcag attgtgcgtt gctccattct aaagcatcat aaagacttcg tccaatcaaa
     5521 aaccacgcac tccgctaaga agcttgcatt atgtatacaa catttgactt gattatacat
     5581 atcgtctttc aaccgttgga atctgacaac tgcactatat atgcacaaat acaaccatta
     5641 tattataaca taacaagtgc gtctttcaac taaatcgaca aattacaaat aagaaatttc
     5701 ttcaatatct ttcagcattg tgcaagcttc tctcagctct cgttcgttaa attcatacaa
     5761 tagatgcaat tcttcgagtt cgatctcgat cccatgcatt tcatagccga ctttatgaag
     5821 tgccgctgcc caaagacttg gatctgtgta cttaggaaga aatggataca gcacaaataa
     5881 gtgccggcgc cataactctt ccacgccttg gtaaagggtt gggttctcat tgccgagcgt
     5941 atcatcgagc atacgaagca cttgctgaag aagcggcatc tgctctggct ttacagcttc
     6001 agaaggaata agtgttaaag aatcaccgaa ttttgtcaca tgaaccggct ttgccacatc
     6061 atgatctgcc agaagctgca ggatcattga tttaaccaaa gggttcccat caggattttg
     6121 taagattgta tttaatagac ccatgtgcgg tgtaatattc cggtctttca atgaatggat
     6181 gaactgtacc tgttcttccg gccgctttag catgtcatct atgttgacct cacttccggc
     6241 gtcctcatca tcatctaaaa tctcttcagg tgagtcgatc atttttctac taaattcgag
     6301 cagtttgtaa aaatgctccg cgctttctgc cggaagatgg ttttcctcga gcacagcctc
     6361 aatcgtctgt ttgacttctt catattcttt cagctgaatt aagatcgtca tatacacttg
     6421 gagcacagtg aaatagtgac catatccttc atgcagcatt ttttcacaaa cacgctttgc
     6481 atcctgcagc tcacccagct ccagaaaaca aatggccatt ccgaggtgaa tatcggattc
     6541 ttcatcgtca tcatacgatt ttgcttctga aaacaagtga agcgcctctt gatactgttt
     6601 atcttttaat gctgccattc ctttttcaat cagtctttct ttcagaccag gaaacaaaat
     6661 gacattgtct ttcttcttgt catgcttcat gcttacgttc ctttcgggcg catatttttt
     6721 atcagtttac caacgaagat tagtaaacac aagtaacgag aggttttcat gcaaaaaaga
     6781 agccgtcaca cctcgggcgg acagcttctc gttgcttagg cgcgcagcca gctgctgcgc
     6841 ttttcttcaa atgcttgaat gtcatcttct agtagtaatg ttaatgaaat ctcatcataa
     6901 ccatttagga gcatttctct ccagtgaggg tcgacttgaa aaggggtgat attcccttcg
     6961 tgatcttcta tttgctgttt ttcaagatca accgtcatct catatccttt gttctcatat
     7021 gacgcagcga aggttttcca cacatcataa tcaaggcgaa tcggaagcat cccattttta
     7081 aagcagtttt gatgaaatat atctgcaaat gatggtgcga tgacaatttt aaagccataa
     7141 tcatcaagcg cccaaggagc atgttcccta gatgatccgc agccaaagtt ctcccctgcg
     7201 atcaaaatgg atgctccttc ataaatcggc tgatttagtt cgaaatcggg atttgggctg
     7261 ccatcggcta aataacgcca gtcgaaaaag gcaaagcggc catatcctgt tcgttcgatt
     7321 ctttttaaaa attgcttcgg aataatttga tctgtatcta cattgattcg gttaagcaca
     7381 gcggcttttc ctttatgagt gactaaaggc tccatctatg acaactcctt acacgactgt
     7441 tttctcttga ttaaacttcc tgacatcgac aaatcggcca tgtatcgcag ccattgcagc
     7501 cattgccggg ctgacaagat gcgttctcgc acccttccct tgacgcccct caaagttacg
     7561 gtttgatgtg gacgcgcagc gctcgccctc cggtaccaca tcgttattca tactcagaca
     7621 catactgcag ccagattctc tccattcaaa tcctgcttca aggaagattt catgaagacc
     7681 ttcttcttct gcttgcaatt taacactttg agagccaggc accacaatcg ctctgacatg
     7741 atctgctact ttttgtcctt caatcataga agcagcttgg cgtaaatcag tcattcttga
     7801 gttcgtacat gagccgataa agacatgctc aatcgtaata tcttctatac gctgatgcgg
     7861 gtggacaccc atgtattcgt aagcacgaat cgcttctttt tgatcatctt cttgtgcaaa
     7921 gtcctcaggt cctgggattg atgcatccac agggagtacc attcctgggt taattcccca
     7981 cgtaaccatt ggtgaaatct tatttccatc taacacaatg gttttatcat aggttgcacc
     8041 tggatctgtt ctaagttctt cccattcttt aatagctgct tcgaagtctt cgccctgcgg
     8101 tgcatatttg cgtccgcggc aatattcgaa ggtgatttca tcaggtgcaa tcaatcctgc
     8161 tcttgcgcct gcttcaattg acatattaca aacggtcatc cgctcatcca tcgtcatgtt
     8221 tctgaatact tccccagtgt attcaatgac ataacctgag ccgaacttca cgccgtgtgc
     8281 accaatgaca gctaaaatga catctttggc agttacccct ttttgaagct ttccgtctac
     8341 tctaatttct aacgttttcg gacgctgctg ccaaagtgtt tgtgtagaaa gtacatgttc
     8401 aacctcactt gtaccgatcc caaaggcaag tgcgccaaac gcgccgtgag ttgatgtatg
     8461 actatctcca caaacgattg ttttccccgg aagtgtcaat ccaagctccg gtccaacgac
     8521 atggacgatt ccttggtcaa cactatgaag gtcagcaaga cgaacgccaa attccgcaca
     8581 gttgcgctct aaggcactca cttgcttttt agcaatctca tctttgatca caaatcgatt
     8641 cacagttggg atgttgtgat ccatcgtcgc aaacgtgttt tgaggtcttc tcaccttgcg
     8701 ccctttttgt cttaatcctt caaatgcttg aggtgatgtc acttcatgca ccaagtgcag
     8761 atcaatatat aaaaggtctg gtttcccctc gccgcttttg actacatgct gatcccatat
     8821 tttttcgatg attgttcgag gcataaccct tttcctccct ctatctaatt ccacaagatt
     8881 ctatttatac aatggtttgt acgcgctgct tgagtgcgtc tacaaccgca ttagtaattt
     8941 cttcagtcgt ttgatatgtt ccctcttttg ctgctaaatc ttttgttcgt ttgccagagg
     9001 caagaacagc ttccacagct tcttctattg cagccgcttc ttcttctaat gcaaaggatg
     9061 ttctaagcaa gcttgctgct gataaaatgg ttgccagagg gtttgcaacg ttttgccccg
     9121 caatatcggg tgctgaacca tgaattggct catataaatg aaggccagtg cttgataaac
     9181 tagcagatgg cagcatgccg agtgatccag taatcatcga agcttcatcg cttaaaatgt
     9241 caccgaacat attctctgtt acaatgacat caaattgagc gggcttgtaa atcagctgca
     9301 tggcagcatt atcgacgagc atatgctcaa attcaacttc tggatattgg gcagcaactt
     9361 cttctaccgc atcccgccat agtttactag aagcaaggac attcgcttta tccacagacg
     9421 tcactttttt ccgtctcgtt aaagccatgt cgaacgcttc ttttaatacg cggacaattt
     9481 cttcctttgt ataaaggagc gtatcaacgg cagcttcttt tccttcatca tccgtatagc
     9541 gttcgcttgg ttcaccaaaa tagagaccgc ctgttaattc acgaacgatg acgaaatcga
     9601 ctccgttaat gtgatcctgt tttaacggag atgcctcgct taaactatcg aacaccttta
     9661 cagggcggat gtttgcaaat aagtccagct gtttacgaat ggcgagtaag cctttttctg
     9721 gacgaagctc tggcgggttt tgatcccact ttggtccgcc gactgctcct aataaaatcg
     9781 catcagcgct tttgcataca tctactgttt cctttggaag cgggttgttt ttttcatcta
     9841 ttgcgatacc gccaatgagc gcagtttcga attcgaattc atgcctaaat tgcgccgctg
     9901 tctcttgaag gacagcgact gcagatgtca cgacttccgg tccgattcca tcgccgggca
     9961 aaagtgcaat tttctttttc atgagaacct tcctcctttc ctatgagatc gcgtgatgtt
    10021 tctcaatttc aatcagattt gatttgaaga ttaaatgcct gttcactgca ttgacgtaag
    10081 ctttcgccga tgcttcaagc acatcttgcg ctactccgcg tcctgctgtt tcttttcctt
    10141 ctattgaaac agtgacatat acttcagcta gtgcatctct gccttttcca tttgattgaa
    10201 tgcggtagtc cagcaaatga attctttcct ccatacagcg ctcaagcgtg ttgtacacag
    10261 cttctacact gcctgcacct gtagctgctt cttggatgac ttcctgtgtt tcttgatttt
    10321 tcagcgaaac cgttgctgtt ggcatttgtt ctgttccata gtgcacttgc agactttcaa
    10381 attcgtaacc gatttttcga tctgctactt tttcttctaa tatgatagag atcaaatcat
    10441 catcggtaat ttctttcttc ttctctgtca agttcttgaa agtctcaaag aatttattga
    10501 tttcgtcttc cgttagttta aagcctagtg ttttcatgcg gtctttaaac gcgtgtcttc
    10561 cggagtgttt tccaaggaca agcacatctg ttgtcacacc gacaagctct ggagaaataa
    10621 tttcataggt tgttttttct ttgaggaaac catcttggtg aatacctgat tcatgtgcaa
    10681 aagcgttgtt tccaacgact gctttattac gcggcacaat cattccagag tatttgctca
    10741 ctacatcact tgtacgctta atttcattca attgaatcgt tgattcgacc tggtaaaagt
    10801 cttttcgaat atgaagagct actgcaattt cttctaacgc ggcatttcca gcgcgctcgc
    10861 caattccgtt gacagccgtt tcaatttgat ctgctccatt ttcaatagca gcaagtgagt
    10921 ttgccacagc cattcctaga tcatcgtgac agtgagcgga caagttgacg cggtcgatat
    10981 ttggaacgtg ttccttcata tatttaaaga tattaccgta ctcttttggc gctaggtatc
    11041 caactgtatc tggcaagtta atgacactcg cccccgcatc aatgaccttt tctacaattt
    11101 ctgctaagaa agcaagatct gtacggcacg catcttctgc tgaccattgg acaactggaa
    11161 aacgttcttt cgcatatttc accattgcga cagcctgttc tacaacttct tcacgtgttt
    11221 tctttagttt atgcttcagg tgaatgtcag aagtggcaat aaagacatga agccttggct
    11281 ccaccccatc ttttaatgct tcccatgcag catcaatgtc acctttcaca catcgtgcaa
    11341 gaccagcaac agaacagttt ttaatcgttc ttgctatttc ttgtacgcct aagaaatccc
    11401 ctcgggatga agcgggaaaa cccgcttcaa tgatattaac cccaaggcgc tcaagctgct
    11461 ttgcaatgat aagcttttct tgtgcattta agttcactcc tggtgattgc tctccatccc
    11521 gaagtgttgt gtcaaaaaaa ttaattttcc gcaccgacgc tcaccgcttc ctttttcttt
    11581 ccttgtttaa cgaaaggcat catttcacga agctttctac caacgatttc aatttggtgc
    11641 tcattttcat ttgcattgat cgcattgaaa cgtgggcgat tcacttggtt ttcaacaatc
    11701 cattcttttg caaatgttcc gttttggata tcagtcaaaa cagctttcat cgattctttt
    11761 acttttgcat ccacaacacg tggtcctgat acgaagtcac cccattgtgc tgtatcagag
    11821 attgaatatc tcataccttc taatccttct tcatacataa ggtcaacgat caatttcagt
    11881 tcatgcagac actcgaagta tgcaagctct ggctggtaac cagcttctgt taacgtttca
    11941 aatcctgctt ttactagtga agtaagacct ccacaaagaa ctgcctgttc accgaataga
    12001 tccgtttctg tttcttcctt aaatgttgtt tcaagaacgc ccgctcttgc tccgccgatc
    12061 gcttttgcat aagcaagtgc tttgtctttc gcttggccag atacatcttg atagatagca
    12121 aatagggcag gtacaccagc gccttgctca tatgttcttc tcacaagatg tcctggacct
    12181 tttggagcta ctagatacac gtctacgtca cttggaggaa caatttgatg gaagtgaacg
    12241 ttgaatccgt gtgcgaatac aagtgagttg ccagcttcta gttgatcttt gatttcttca
    12301 tcatatactt tcttttgctg ctcatctgga agtagtacca tgactacgtc tgcttgtgct
    12361 gctgcttctt ttactgtgaa tacttgatgg ccgtcttctt gtgcttttgt ataagatccg
    12421 ccttttctca cgccgacgat cacatctacg ccgctttctt ttaagttcaa tgcatgtgca
    12481 tgaccttgtg atccataacc aatgatcgct accttttgac catttaatac gttttcttga
    12541 atatcaccgt tataatatac ttttaccatt tgactctctc ctttttgttt agacaattga
    12601 aattgtttta tttgtttgcg gcttttgctg attatctctc gcaaaggccg tggtgccagt
    12661 tctggcgact tctttaatgc cgtatggctt aagtaattca atgagtgctt caatttttga
    12721 agactcacct gtcacctgaa tgacgacact ctctctgctc acatctacaa tagaagctct
    12781 aaaaggttca atgacccccg tgatctccat tcgagatgct ggtgcagata cgacttttat
    12841 caaagccagc tctcgctgaa cgattgattg gtttgtaatg tctgttactt tcagaacatc
    12901 gatttgtttg ttcagctgtt ttgtcagctg ttcgatgtct ttctcctggt ctacatggac
    12961 gacgaacgtg atgcgtgata catcttgaat ctcagaatgg ccgaccgtaa tgctttcaat
    13021 gttgtagtgt cttttggtaa agaggcctgt gattctgttc agtacgcctg atcgatttaa
    13081 tacagtcaac acaataattc ttttcaaggt ttcaccccca ccatctcatg aagtcctttc
    13141 cctggtgcta ccattgggaa tactttttca tctctcgcta cattgacatc gatgaaaaca
    13201 ggctctctag aggttaaggc ttcttcaagc ttttctttcg cctcttcatc tgatgagatt
    13261 ctgattcctt taatgccata agcttcagat aatttgacga agtctggctg ctctgaaaat
    13321 ttagaatgtg agtagcgctc ttcgtagaaa atttcttgcc attgtcttac cattccaagg
    13381 cagtgattat tgagtacaat cactttgact ggaaggttca gctcacggat aacggcaagt
    13441 tcttgcaggg tcatttggaa acctccgtct cctaaaatcg ctacaacggt tgcctcttga
    13501 tcagctagct gagcgccgat ggctgctggt aatccgaagc ccattgtgcc aaggccccca
    13561 gatgttaccc acttatctgc attttcaaat ggatagaatt gtgctgccca catttgatgc
    13621 tgtccgacat cagttgcgac aatggcttca cctttagtga attgatgaat gtattcaatc
    13681 agcttttgag gcttaaagcc ttcagcttcg ttttcaacgt accagagtgg atattcttcc
    13741 ttccactgat ctaattgatt tttccattcg tcagcatctg cttgtttccc gtcttgcttg
    13801 atcagttctt caaggactag cttactgtcg ccaacaactg ggatatgggt atgaatgttc
    13861 ttgccgattt ccgctggatc gatgtcaata tgagccacct tcgcatgttt cgcaaaatga
    13921 ttgaggttgc ctgttaccct gtcatcaaat ctcgctccga ttgaaatgag caggtcacat
    13981 tgatgaagag ccatgttcgc tgcatacgtg ccatgcatac cagccatccc taggaaaaga
    14041 ggatgctttg ccgggaatcc gccaagtcca agcaatgtat gagcgactgg gatttgctgc
    14101 tgctctacat attgtcttaa ttcttcagat gctttgccat gaagaacgcc agctcctgct
    14161 agaatgactg gtttcttcgc tctgctgaca gcttctacta atttgcgaat ttgcaaatag
    14221 ttcggctcta cttttggctg ataaccaggt aaatcaattg gctgatcata ttcaaacgtt
    14281 ccttcaatgc ctgcgacatc ttttggaata tcaatcaaaa ctggaccagg tctgcctgtt
    14341 gttgcgatat ggaatgcctc tttaatgaca cccggcaatt cctctggatt tcttacctgg
    14401 tagctgtgct tagtaattgg cattgtgatg ccgagtacat ctgcttcttg gaaagcatcc
    14461 gatccaatga ctgaggttgc cacctgccct gtgaatacaa caaggggaag tgaatcaatc
    14521 atcgcatctg caattcctgt gacaaggttt gtcgctcccg gccctgatgt tgcaataaca
    14581 actcccggtt taccagatac ccttgcgtat ccttctgctg cgtgaattgc tccctgctca
    14641 tgtcttggaa ggacatgaaa caaaccagaa ttgtaaattt tatcgtagat cggcaaaact
    14701 gctccacctg gatatccaaa aatgacttct actttttctc ttttgagtgc ttcaattaac
    14761 atgagtgcac cgttcatcgt ttgtggtgct tttgattttt ccgtctccat ttgtacattt
    14821 gtccccattt gatttcctcc tctttgtctt gcttcagtca agtcctttca cccttttcta
    14881 ttcaagatag agatatgaga ccatataaaa aagccttctc accccacaat gacactactt
    14941 ttcactaggt caaaggggcg aaaaagcttt gttttttcgc ggtaccaccc ttgttcacgg
    15001 caaatcctgc tgccgtctca tggacatctt tcgtccattt tggtaacgag tgagcaatgt
    15061 cactcggtct gccctactat catttcaagc agacactcag aggtgagttc actttagaaa
    15121 gtaacaccgg tttccagcta gcaccggctc tctgtagata ctgactctaa agctactagt
    15181 cctcttcaac gtttatcgat atctatttag cttgcatgaa tgttttcatc tgcaaaaacg
    15241 actttttctc cttcttcaac tactcgcttg cggaattgtt caagaagttt gtttgtgtgg
    15301 aacccaggtt tcccttcacc gattgtacgg ccgtcaactt ttacaacggc gatgacttcg
    15361 gctgcagtac ctgttagaaa tacttcttca gctgtataca catcgtgtct tgtgaatggt
    15421 tcttctttca cttcgtagcc taagtcttct gcaatctcca tgatggcatt tcttgtgatg
    15481 ccttcaagtg cgccgatata acctggcggt gtataaagct tgcctttttt ataaataaac
    15541 acgttgtctg cagaaccttc cgccacgtac ccttgatcgt tcagcatcaa tgcttcactc
    15601 acaccggcca tatgggcttc gattcggaca agaatgttat tcaaatagtt taatgatttc
    15661 acttttgggc taaggacatc tggacgattt cgtcttgttg gaaccgttac aatatcaata
    15721 cccgtttcat ataggtgctt tggaaaaatg gccagcggct ctacaatgat cactgtgttg
    15781 gctctcccgc agttgttagg atctaaacca agatcacccg ctcctcttga gacgacaagg
    15841 cggatatagg catcctttag gccgttcctt tcaactgtat gaatcatttt ctccgtgagt
    15901 tcctcaagtg aatatggaat gttcagcata atggatctgg cggaatcata caggcggtct
    15961 aaatgttctt tcattcgaaa gatatttccg ttatacacgc gaatcccttc gaaaacaccg
    16021 tcgccatata agaagccatg atcgtaaact gaaattttcg catcctcttt tttcacgagt
    16081 tcatcgttta aaaagatcca ttgttccttt tggtcttcca ttttcagtga gcaccctctc
    16141 tttcaaacaa aaagtagttg aattttcaga cactttatat tgaagcgtct ctcgcttgca
    16201 ctgcgtgttt gtttagcttt tgttgaaccc atcttacgcc gctttccata cagtgtcaac
    16261 agcattttta aaattattag acaatttaga ctaatcaaaa ttaaatgtat acgcttacac
    16321 ctttgctaga caaggaatga aaaaacttaa aattttttgt attttttctt caatttattt
    16381 actttacatg aacgcttttc ttttgagaaa acttttgtga tattttttca catgattttt
    16441 gatgaatatt gtgagatttc aatgacttgg tttttacttt tgacatgcct ttctaaagcg
    16501 ttttcctatg aatttatgat agaatgagag catctaatag aaggagggca atacatggct
    16561 aacatcagag gttatatcgg tacgtataca aagggagaca gtaaaggtgt ttatacgttt
    16621 acattaaata cggacaagca gcagattgag caagtagaag ttgctgctga acttgaaaat
    16681 cctacatatt taaccgtgtc agaggatcaa aagtttgttt atgctgttgt gaaaaaagga
    16741 tcacagggcg gccttgctgc gtatcaaatt gattcaacaa caggcagact tcacttcatc
    16801 aaccaagagc ttgccgatgg agcttctcct tgccacgtca gcgtggacag tcaaacgaaa
    16861 acggcgtata cagcgaatta tcataaaggg tcagcagaga tgtatgaaat cgatgctgaa
    16921 aatggctcag tgatccgcac actctcacag gcgcagcatg aaggaactgg ccctaacgaa
    16981 gatcgtcagg aaaaaccgca cactcacttt atgggtctca cgccagatga acaatttgca
    17041 gtggctgttg accttggaac agatggaatt tatacgtata agaaagaaga cggcaaactt
    17101 gagctttctc atacatttga aacaaagcca ggcagcggac ctcgtcatat cacattccac
    17161 ccaacgaaac ctgtggcata tgtaatgaca gagctaagct ccgaggtcat tgtgcttcgt
    17221 tactttgaag atggtcattt tgaagaaatc caaacaatcg cgaccattcc aagcgatttt
    17281 acagagaaca atcaaggcag tgccattcat gtctcttcag acggccaatt tgtttatgca
    17341 ggaaatcgcg gtcatgacag cattgcgatt tttaaagcag acgctgacgg ccaattaagt
    17401 cttgtcgaga ttgcttcttc tgaaggaaac tggcctagag attttgtact tgatccaaca
    17461 gaagaattcc tcgtcggttc aaaccaagaa tctagcaatc ttgtgttata caaacgcgac
    17521 aaagaaacag gacgactcac tgtcttacaa tcagacatta ccgtccctca tccagtttgc
    17581 gtgaaatttt tagggtaaag aaaaaagcct ccaataacgg aggcttcaga ttgttgacaa
    17641 agggctaaaa tgattttgat tttagccctt tgtcttcttt tcagcgtgat agaaaacctt
    17701 tgcagtctag gaaggacgag caccggagcg gagcgaattg aaacattcgt gagcactgga
    17761 gcgcagacct gacaacgaat gcgagggttt gtctacacgc taaagcctcc aataacggag
    17821 gcttttttta tgcagacggc ataccgccat cctcaagctt ttgatcaatc aaagacgtat
    17881 cggttttttc gccgaaccat tttgatagcc tgtcttttgc tttccctttc acatcatcat
    17941 caatgtacat tgctacttga agcagagcaa atgtaatggc tcctaaatca tctgtatagc
    18001 cgacaccaat caatgtatca ggaatgagat caagtggaag gataaaatat ccgagtgctc
    18061 caataatcaa agtctttgct ttgaccggca cttcgggttt ttgcaatgta tagtaaagta
    18121 atagcacagc atagacaaga gagacaccag ctttttgtgc cgtctttttt aacttttccc
    18181 aaaaggcatg atcattaaaa tgcttcttcg aacgctttaa tagttctttt ttctcagaac
    18241 gattcatcat atcgcctcca tctacagcat agcccttttc ccttagttat acaagatatc
    18301 cgccgattcg acaaacaaaa agcagcagaa agctgctgca ttctactgct ctttgtaaaa
    18361 cttttcaatt gccttatcga tgtacaccca tcctttataa gacacatgaa tcgtatcttt
    18421 aaagaaatat ggatcgtact catgcttagt caaatctgcg acttcatacc cattatctcg
    18481 aatttgacga ttgatttttt cataataacc tgtacggcct tctttcggaa aaccggtgta
    18541 atcataccac tttccgttga caggaatcgt cacaaacaaa ggctttgccc ctgcctgttt
    18601 taaaatatcc agcatgatct gaaaatcttt gtattctggt gattccgcat aagaatgacc
    18661 ttcacgggaa tccttcatct ttttcatgat cggtttcagc ttgcggtcaa acagtttttg
    18721 gttaatataa aacgggttgt cccctgctct tttcgcacca aaaatgctcg cctctttttc
    18781 aagctcagcc catgtttttc ctttgactga aggagacggt tgaagcttgc gctcagggcc
    18841 cgatccaatt gtatagtaca tgtctttctt ttgaagcatg ccataataca ttttcgcaat
    18901 aggagaaatc gcgccataag cgaacttgtt cccagatagc tctgctttaa aaagctctgt
    18961 aatcaccatg tcgtttttga ctgctttaaa cttcatgatt cttttgataa gctctttttt
    19021 tacagttgga tcaatttctt tattataggc gagattcagc gcttgaagag ctgaatagtt
    19081 cggtgcaaag tgattctcgt cagatcccca tttcacaaac cattgcgggg acacgataaa
    19141 tacaagcttc ttccctttta attcatccat atgcgctgca aagttcatcg catgaattaa
    19201 tgattgcgat ccaccttttc caataagata aggtgtaaac ccttgaggat tctcatgaaa
    19261 gaaattcgaa gggtgatatg gatcaaaacg tgatagttca gaagatccat agatcggcaa
    19321 ataagttgga tcttttagca tttcatcttg taaataaagc ccttgaaaca tccctggatc
    19381 taattctgtg gctgactttt gtaatttgtc ttttgggatc aggtgtgaga gccatgcatt
    19441 tggtacaaga agaacaccaa tgaatagaac agccgctaaa ataagcggcc caaaaaaacg
    19501 ctttttcatt acttcatctc tgccagctgc tcagcaatat gattcggcgt atcccacaca
    19561 tcacgatcga attctgtaat cggaacagtg attccgagtt gactttcaat tgccataagc
    19621 agttctactg taccaaatga atcaagaaga ccttcttcaa aaatcgcaat ctctggattt
    19681 tctttcacaa cgtcatcctg acaaacctct gcaataatac cgtatacttg atttttaaat
    19741 tccataattt tctactccct taatcattaa tgatgaaatg gttttcctga aaaaatataa
    19801 aatccgaaac aaatcacatg gaatgtaata atgatcgaca caaccattgt gaccttatta
    19861 tccggccacc acttgtgctt tttattccat ttctcaaata aattgtaacc ggacatgaca
    19921 actgcatgat atagtccgta aataatatat tgaagggcaa gaccatgcca agcacccatc
    19981 aatagaaaga ggataaagta cccaatattt gaaacagcca tacggttctt gatccacttc
    20041 tttttagtca taaagaacac aaatctcata aacacgtagt ctctgaacca aaaagacagg
    20101 gacatgtgcc agcgattcca gaagtcttta atgtttcggc tgataaatgg tttattaaag
    20161 ttctctggtg atttaatgcc cataatataa ctcacaccta cagcaaatgc tgtatatcca
    20221 gcaaagtcaa agaacaagta catgctgtaa gcatacatat acgttaactg ctgaacaaag
    20281 tgactgctgc taatgtgatg aatattcatc agaatatatg tgtgaatcag atagcctata
    20341 atgaacttat ataagaagcc aataaaaatt ttatgaatac cggcatatag aagatcactg
    20401 tatgcttcct tttcaggcgg tgtatccata tccttttcaa atcggcggta acgatcgatt
    20461 ggacctgatg aaatcgtcgg gaaaaagaca atgaaataga ccaaacggtg aatcggaatt
    20521 ttcttcttaa tcaagccgtc tcttgtctca ataattaact gaacaccttt aaatgttaag
    20581 tacgagatcc ccaaaaagct cagccagttc attggcggcg gttgatgcgg ctggtgagtt
    20641 aaaaagaacg gtaaaatctt tgacagcaca agcggtaaaa tagatgccac cactgctgta
    20701 tagaaaacgg atgcctgatt cgcctttaac cggtatgcaa ggtacaggcg gatgattaag
    20761 acttgccaca ccgtgaacaa gaagagcagc agcgcgccat gtgcatcctt tgagaaaata
    20821 agcgccagcg ccacaaccgt tgcaaacatg ttgtagccct gcattctttt gccgcgcaga
    20881 ccaagaatga tcgtcggcaa aagaagaata ccaattagaa tgaagaaaaa gaatgaacta
    20941 aacggaatca tagaagaacc tctttcgcga ttctcttacg gtcaaccttc ccgtttggcg
    21001 tcatgtacag ctgctcaaga tagacaaact ttcttggaat catgtacgct ggcagtgaat
    21061 ccgccatttc tttcttaatc gcacttgtca gccgatattc tttttcaaat gaatgagctg
    21121 ctgggacaat cgctgcaatc aagtactcga catgaccgtt tggctggaat ggtacaatca
    21181 cacaagcatt gacataggtt gtctcgctta catgatattc aatttcttca agctccatcc
    21241 ggtatccatg aagcttaatt tgatagtcga gacggccatg gcacgtaatt aatccatcat
    21301 gcgccacacc tgcgtcacct gtacggtaag caggacgtcc ttcgtattca aagaacactt
    21361 tatctgtcaa ggcttgttca cctaagtagc ctctcgtgac gcttggcccc acgatgacaa
    21421 tttccccttt ttcaccatca ggaagtgtct tgccttcttc atctaaaatg acgatgtctg
    21481 tatcaggttt ggcatagccg actggtaaag aatcgtgctg atcaagaatc tcctgcgtca
    21541 cttcaattga tgtgatcgcg acagttgctt cagttggacc atacgtatta aagacctgcg
    21601 cctttggaaa acgctccaga agtgcacttg ctacagctac aggaagcgcc tcaccgcaga
    21661 acaagaaaac tttcagctct ggtaaaagct cccctgtaaa ggaagggtcc attaagcaca
    21721 tttgcacaaa agaaggtgtt gatgtccaca cttcaacgtc agattgacca agtgctgcaa
    21781 acatatcctt tggcttattg acgaaatctt ttactaaaca gtaaagcgtg ccgcctgatt
    21841 gaagcgctgg atagagatcc atcactgata agtcaaaaga aaatggtgct tgatttaaga
    21901 atgtacgtcc ctcaccaatt gggaagtcac ggcacatcca ctctgtaaag ctttctaaat
    21961 tattggctgt tacctgaacg cctttcggtt ttccggtact gccagacgta taaataatgt
    22021 aaaaaacatc atcttgttga acccactgcg tggatggcgg tgcttctttt tcaagtgcta
    22081 aaagcgatgc cgcactcttc acttcaatgt gctcttctac atctaataca ttctgctcat
    22141 ttgcacaaat caatagactg gcttttgagc tttcaataat tgagacgatg cgctcgacag
    22201 gtattgagat atcgaccgga atatacggtc tgcctgattt cacactgcct aagaaagaaa
    22261 tcagcatctc tggctccata tgaccgtata caatgacagg ttcactgcca gttgcgactg
    22321 catcgatcgc accagccatt tggtctgata aataccaaag ctcatcatat gtgatcgtcg
    22381 catgttgaga aacaaatgct ggctgtgttg gtttcgtttg ctggtattca tgaatcgttt
    22441 gtaatagttt cataatctaa tctccaatta aaaatcgttg taaatgaatg atcccgtatt
    22501 tgctgtatgg aatccgtaaa taaagaacaa taatagcaaa ataagtaagt aaaagcttgt
    22561 atatcctatc cattttacag acttattttc tgatagcttt ttgaatagca tattgataac
    22621 ctcttttctt ttgacactta tagagacgca tggatcatca aaagagtttc atatcaaacc
    22681 ataaattttt taaaagatgc taaaaaaatg tcgaaccttg gaacgtctct tttgagcaaa
    22741 gctgtcttat tgtaacaaag atttaataca tttgaaataa aatccgagct taaatttggc
    22801 ttaaaattgc tgaaagctgt cgaactaacg caaaagccac ctagttggac tagatggctt
    22861 tgttttcaat tacttcttat atttattgac ttcgaacatg agaatgttgt tgaataccac
    22921 atagtccttt ttactttcaa aaggaccttt attgttgtca tgttcgtcaa tttcataaaa
    22981 ccctgggcct ttacctgcat cacgcttttt gtaccaagag aggaatgcgt tgacttcttt
    23041 cattgaaagg tcatactctt tctgtaagcc attgaccatt gtgatgatga gaagggcatc
    23101 gccgtcttca tttgttgtat cgtctttagg cggtgtggtt ggttcttggt ctttgtctcc
    23161 tggatttgtc gtaccatctt ttggtggtgt tgctgtatct ggatctttgt ctcctggagg
    23221 agctgtagtg tcactgtttt taagactttt tagtgaaata gataaattag atttgaaatc
    23281 gtccctagcg tagttaggag catcattact ctgtggaata cctccaatta cataaagtgt
    23341 atcatcaata atggcggata catgccccat acgataagga gcagaagaat tagggacagt
    23401 tcttgatgtc ttagtttgct tatcatagag tgtaacttta gaaactccac ctgttcttat
    23461 aatataatct tcaaaattta atgcactata ataacgccca atccccccag atcctacact
    23521 tgtccactga tctattgatg gatcatattc aaacgttgct tgtccagata aaacatagag
    23581 tttatttttt ataactacag catttccagc aggagcgtct ttttcaaatt ttttcttctt
    23641 tgtccattct tttgttttta tatcgtaact atacgtgtta ctgctgtact tctcgtgctt
    23701 taacggttta ttataaccca aaacatagat tttattatct atagcacctg cgtataaatc
    23761 gaaagcagat attttcaatt caaatgggag gtcttctgcc tcttcccatt tatccatttt
    23821 gatgttataa acttctacgc tatttgaaaa cccttgatct gttctcccac ccattacata
    23881 tatatgatcc cctacaatag cactagcagc acccatacgg cctgttttca tactagcttt
    23941 ttctgaccat ttatctaact tcggatcata tacataagta gtattagaat tggccttacc
    24001 tgaacctatt ccacctatta catagatttt cccatcatat acttcgctta cagctcctac
    24061 tcttgcagct ggcaattctg ctcgtttttc ccattcaaga atatctgcct tttctgcttt
    24121 tattgattgt aatggataaa ttaatgcaga aattaataaa acgaaaataa aaaaccattt
    24181 tttcaagata accacactcc ttcaatttgt ttacataaca aatatcggat agttatttat
    24241 tttttccatg tttttgttac ttatatatat ttattactta tttacttacc gtttccccaa
    24301 tgcgcctata aatttctaaa atcagacttc gtaattagaa ttattttata tttaagttaa
    24361 ttaattgcag taattctttt atttttctat ttctccgtca aaaaacaacg attcataggt
    24421 ttcttctcag cccattatta gaaaatctgt cacaaggcaa gtgagttctc cattttcatc
    24481 tagcccccaa taacttggat acatcccgtc accaaagact gttgtaaaca cggcaatgtc
    24541 caccttgtca tgaaaacggg tgacgagcca gtcccatgtg tgcttgtagt tttgctcaag
    24601 cgcttctgca attcctcata aagataaaaa tcattgtcct ctttatatcg cttatcctta
    24661 taagcttgga gatatagtgc tgactccgtt atccataaag cagcccatac ccgtatttac
    24721 accgtagccg aagaactcgt cttctttcaa ttgattgagt tttgccctat tcttgtagca
    24781 agctcccatt ctattgctag ctcgtttgta aacttgatca ttgcataggc tactcgttcg
    24841 tctccgcttt ccaaccgctt aactacaaat ataataggat attttcctag agtaaccttc
    24901 ctcgtaaaag attgatcccc ttctgaaaca aaaggatcac aggcaacaat atgaccgctc
    24961 gtgatctcga tagtgcctta ctgtttagca aataattgat caccctcttg attgcttgtc
    25021 tctccatttc tatataacaa gtgtgttgga ttgatgttcc aagtgatcat tcctttcatt
    25081 gtttttctgg ggtgttttgg attatgtact tttctctgtt ttgtttttta ttcccgcttt
    25141 atttccccta tttaatctgt ccaacctact cataatagct tactgaaccc cttcaaataa
    25201 ctcctttaca actttattca ttattaatac ttggattagc agtaaacaac atagatatta
    25261 aaagggaata agtacgtttg gagggaatta aatgacacaa gaatctgatg agcgtaagtt
    25321 gcaacaaata aaacaaatgc aacagatgtt tctagagaaa atgaaaactc aaccttatcc
    25381 catgtaccct aattacggaa aaatcacacg ctatgaagaa atcccaatta atttacctga
    25441 acaacgtcaa cttcgtcatc ctggtgtaga aggtttaatg gtaccacttc caattattga
    25501 aaatacaaat tacaaaggga gtggtaagtt agcgggaaaa gttgctctta ttacaggagg
    25561 ggatagtggt attggtgcag ccgtagccat tgccttcgca aaggaaagtg ctgacgttgc
    25621 gattgcatac ttagatgaac acgaagatgc taatagaaca aaagcaagaa tcgaagaact
    25681 tgggcaacgt tgtttattga tgccaggaga cttgcgagat aaaaggcaat gtatcaccat
    25741 tgtagagaaa acagtaaaaa ccttcggtcg tctagatgtt ctatgtaacc acgttggtat
    25801 ccaatttcaa caaccaagcc ttcttgacat tacagacgaa caattcgatg acacctttaa
    25861 agtcaacata tactcacatt tttacacaac cagagcagcg cttccttact taaaaccagg
    25921 cagttctatt atcggcactt cttcagtcgt aacgtatgta ggtgagcaac aaatgattga
    25981 ttatacagcc acaaaaggtg caattgttgg ttggacacgt gctttggcta aaaatgttgt
    26041 aaaacaagga attcgtgtaa acgccgttgc tccaggtcga atctggacgc cactcattgc
    26101 agcaagcttc tcgtcagacc aagtggctgt atatggagca tttaatccaa tggaacgagt
    26161 tgcccatcca tttgaacttg caccaacatt tgtttatcta gcttctgatg attcacgttt
    26221 tgttacaggt caagtgctgc atgttgacgg tggggaatcc acacattcct aatataagga
    26281 ggtcattgga ttgagatatg aatttaatcc agaagtagag ttattacttg tgaatcattc
    26341 aatgaaaaaa gttactatgg tttatatgga gcattcatgg ctaatgtctg aaattggacg
    26401 tagaccgcct tattattgct acccaaatta cgaactgaat gatccaatca tttaaataaa
    26461 tcgcagttat gcaggaacgt ttagggcata caaaaatgga tacaactatg tcaatttacg
    26521 cttctttgat acaaaaacag ggaacggaaa tacttaaaaa taaatccgat cccaaaactc
    26581 tgttttggag cgagttacga acttaatttc caaggaacaa aaaagcctga aatccttgat
    26641 aataaaggat ttcaggcttt taatttagta cgtcccagga gagattcgaa ctcccgaccg
    26701 acggcttaga aggccgttgc tctatcctgc tgagctactg ggacatgttg ttatgtagtg
    26761 tgctttggtg tattacctca gcgacaagat ttattatatt actattgttc tttaaagtca
    26821 acggtttttc gaaagttttt tcataagggg caaatgctgc acccttatga aataccttcc
    26881 aatgtgacag tgttttcgag gtcttttatg acctggcctt cgtccgtgaa aaactgtacg
    26941 tttgcttcgc ttccatctag tgtcagtata gcatagctgc gctcttttcg cactcttggc
    27001 aggtgcacgc tgcctgggtt aatgaggagt tttcctctta gcagttcact gcctgggatg
    27061 tgcgagtggc caaagcagat aatgtctgcg cccagctctt ctgcacggta gtagacttga
    27121 agtaaggatt gtttgatgcc atgcagatgt ccgtgagtga gaaatagttt tccgcctcca
    27181 tcaagtggga gcaggagctc ttcttcaaaa tcgcccataa agtcacaatt tcctttgacg
    27241 actttgtatc cttcgagtgc tgggtggttc gtttcgagtt ctgaatctcc gcagtgaatc
    27301 atcatgtcaa cttcagctgc atgccgtttg gcaatggttt gaagttcgtc tgtgagtcca
    27361 tgactgtcac taatgatgag tatcttcatg gcttcattcc cccttattca tttgcgtcta
    27421 gcagtgatga aagcttttga agcgcgaccg ctcgatggct gatcttgttt ttctcctctg
    27481 gtgataactc ggccatcgtc tggtctttgt ctttgacgat gaaaattggg tcgtatccga
    27541 agccattttc gccgatcggc tcttctgcga tgaagccttc tactgatcct tctaccgtct
    27601 ttgtttcttt tcccggtatg ctgacagcaa gggcacatct gaatctggct gtacggtctt
    27661 ctttttcaat gccttgaagt tcgctcagca ctttttccac attctccgca tcgtctttat
    27721 gctcaccagc gtatctcgct gaatacacgc caggttttcc gcccagataa tcaatggaca
    27781 gaccggaatc gtctgcaatg accatttcac ctgctttggc ttggatggcc tcggctttga
    27841 tgatggcatt ttcttcgaag gtttgccctg tttcttcaat ttcttcagta aagccaatgt
    27901 ctgctagtgt tttgaccgtg aatccttttg gctcaagaat ggctttgaat tctttcgctt
    27961 tgcccgcatt gtgcgttgca atgatggctg ttttcatcct gatcaaaccc ttctctttat
    28021 tcgatgactt ctcctgttac tgctttttgc ttttcgatta attctttgat gcccttttcg
    28081 gctaaatcaa gcagtccgtt tagctgttct cttgagaatg tcgcttcttc gcctgttcct
    28141 tgaagttcaa caaagcgtcc agcgcctgtc atgatgacat tcatatctac ttcagcagaa
    28201 gaatcttctt catagtttaa atctaacaga agtccttgct gagaatcaat tccgacggat
    28261 atcgccgcta aataatcagt aatcgggttt tctttgataa ctccttcagc tcgtagcttt
    28321 tgaatcgcaa gtgtcatagc aacaaaagca cctgtgatgg acgctgtgcg tgtgccgccg
    28381 tctgcttgaa tgacatcaca atcaatccaa attgtgcgtt cgccaagctt ttctaagtca
    28441 acgactgcgc ggagtgctcg tccaattaaa cgctgaatct ccatagtacg tcctgtgact
    28501 ttacctttag atgattctct tatcgttctt tgtgcagttg ctcttggaag catgctatat
    28561 tctgctgtga tccagccttt tccttctcct cttaaaaaag gaggtacgcg gtcttcgatc
    28621 gatgcgttac aaatcacctt cgtatttccc gctgagatta agacagagcc ttctggatgc
    28681 gtgatgtagc ctgcctctat ttcaattttt ctcaattcgt catattgtct ttcatctaat
    28741 ctcatgtttt acctccgtta cgatatacat tcctcgcgag tgccagcggg gttctcctac
    28801 taactttgac aacctcagct cgttctaatc gcttggaata aaaaagaggc agcgaatatg
    28861 catgcctctt tttctccatt atatcaatgt gtgacgttaa aaactacctg tattcacttg
    28921 ttctggtcgt gaaaccggct ttgtgagctc tgctcccttt tcgttcacaa gctcagcctt
    28981 gccgttcacc ttgacagata cgcttttgac gtccggcagc tcggttaatg tgagcacaat
    29041 gctatcaaga actttttgtg aaatgacctt tttcttttca tctgcactgc caaaaatcga
    29101 ttcattgaaa tcaagtgtca catgtccatc ttttactttt ggtacatcat tcagcttcac
    29161 atcttgatcg aagtctgtaa gcagatggct ttttttgctt ggtccagaga cgagctcatc
    29221 aatcgctgct gtaatcggat catcctcgtc ttttggtgct cttgtggtga ccggaacgta
    29281 gtaggtctgt tcatcagatt cagctaaata gtataccgtc actggctttg tcgatgtcat
    29341 atcagcggca gcctcgtgct ggatatttat accgtcctct ctgcttaaat catctgagat
    29401 tggcgtaccg ttcacaggca tttcttttag ttcatgtcca ttcatcttca atttgacttt
    29461 ggctatggaa tcaaactggg ttaacgtcca agtgacagat tgcaggatgc gctgttcgtc
    29521 ttctttttta tagtttttaa attcatttga aaaatccaca accgccgttc cgtctttaat
    29581 atcgacagat acgctcgtgt ccgctggcaa aactgctctg aatccatttg gcattaagtt
    29641 agaaataggt cccccgtcca cgagatattc aagggtttgt ttggcacttc cttcattttt
    29701 cggcagcgga atggattgag atacgacata cccgttttta tcaattaaat ataattctct
    29761 catcactgta tcagcctgct tctcttcttt tccttctttg gctgtttgtt tgtcttcttt
    29821 attttctttc acatatgtga cgttttgtgg tggatcaatc tctgttttcg cttggtctgt
    29881 ttgaaacaat ccgcatcctg acaaaagcat ggctgacgcg atacacgtaa cagctgctgt
    29941 agatcctttt ttcagcatac ttcaccctcc tctagtagtt tgtactacta tgtatacgag
    30001 ctccctcgga ggattagacc cttttcataa aaaaataacc cacttcaaat agaagcgggt
    30061 tattgctggt agatgtgttc aagtgacacg gtttcgacct tccctggcag gtagccaaac
    30121 cagtcacgag cgatgttttg aaaattttgc tgctgtcctg ttgtgtaaaa tgtatgaaca
    30181 ggcgcttctt tagaggtatt taacagccct ttatatgaaa gaatcgtact tgcttctctc
    30241 gctgtctcat ctcctgatga aatgatgctg acatcactgc ccataaagcg ctgaatcggt
    30301 tcttttaaaa ttggatagtg tgtgcagcca agaataagtg tatcaattcc tgtttctttc
    30361 atcggttcaa gggaatcttt caccactgcc tctgctgtct gatctaaaaa cgtaccgctt
    30421 tccacaaatg ggacaaggag cggacacgcc agactttgaa ctgttaggcc tgcttttagt
    30481 gacagcagtg cttctttgta tgcctcgctt ttgatcgtat tgactgtgcc aataacgcca
    30541 atatgctggt tgtttgtcac cttgatcgct gtgcgggcac cgggctgaat gacgccaatg
    30601 accggaatat caagcgttgc tttaatttca tccagtgcga tcgccgttgc tgtgttgcat
    30661 gcaatgacga gcattttaat atggtggtgt tttaataagt agtgtgccat ttcccacgta
    30721 tattgaagaa cttcttcttc tttccgcggg ccatatggac atcgttttgt atcgcctacg
    30781 taaatgattt tttcttttgg cagttgtctc atgatttcct ttgcaacggt taaaccgccg
    30841 acgccggaat caatgacgcc gattggttga tccaacaaaa tcgcctcatt ttcttttcat
    30901 ttgctgctgt agtttcgtta aggattggtt gaaaacgatg gcttcttctt ctgagaaagc
    30961 ccctagaagt tcactgacgt attcttggcg tttagcaatc acttcttgaa tgatcctctc
    31021 gccttcaggc aataaatgaa tgcgaaccac gcggcggtca gatggatctt tcacccgttc
    31081 gacaagttca cttttttcca ttctatcaat taaatcagtg gttgtgctgc aagccaagta
    31141 catcttttgt gacagctcgc ctattgtcat atctccgaat tcataaagcc actgaagccc
    31201 gatgaattgt ggaggcgtaa tcgtatattg attcaggatt tctctgcctt tttgcttaat
    31261 aattgcggca atgtggcgca atgatttttc aatctctgca acatggccag actcattcgt
    31321 ttccatttta ttgatacctc actatagcat ctcactttga ttaaaacgta catgtctatt
    31381 ttcctcgttt ttcaaagaaa atgcaagaag agactcatgg aaaccatata gaaataaccg
    31441 gttccttccc gatatggaag gaaaaccggc tgactttaga gctctagctc acccatacgc
    31501 agaagctcga ctacagcctg tgaacggcct ttgactccta gcttttgcat ggcattcgaa
    31561 atatgatttc gaacagtctt ttcgctaata aaaagctcgc ttgcaatttc ttttgttgtt
    31621 ttatcttgga cgagcaattc gaatacttct ctttctcttt tggttaatag cggcttggat
    31681 tgaaactctt tctccttcaa gtattgtaac cctccttgct aaggtgagag ctctagtctc
    31741 tatagaatgg gattctttat agtcgagata tcatatgccg agtgcctgag gtaggtgacg
    31801 ttaaaatcaa gaaatcccgc atatcagcgt ccaatttctg cgctttcatc cacgcaaaaa
    31861 aggacgagtc tcctcccgag acatcgtcct ttttgtgtgg tatttaaaag attgaaatgg
    31921 cgcctgttaa caaggcaata agtgttgtaa aaagggcagt taacacggtc caaagtagtg
    31981 cgtatttttg caaatcgccg atatctttat tcagcatacc gacaagcagc atcgttgaag
    32041 ccacaagcgg gctcagtaag tggacaggct gtcctatgat agaagcacgt gcaatctcca
    32101 ccggatcaat cccgtaagct gcgccggctt cagccaagat tggcagcacc ccgaagtagt
    32161 aagcatcatt tgaaagaaca aatgtaaatg gcatactcgt caaagcaaca atcagcggga
    32221 aaaatgagct gtaggaatct ggaatcatgt aaatgaccaa attggcaatg gcctcaacca
    32281 tttttgttcc tgaaaagatc cctgtgaaaa tccctgctgc aaatacaagt gtaatgaccg
    32341 ttaatgcgtt tcctgcatgc gataaaattc gctcgcgctg atcttcaacc tttggatagt
    32401 tgatcataag agcgatgaca aatccaatta agaagagtac aggaattggg atg
//
