LOCUS       NZ_CP034414            20906 bp    DNA     circular CON 27-MAY-2024
DEFINITION  Bacillus safensis strain BLXSC chromosome.
ACCESSION   NZ_CP034414
VERSION     NZ_CP034414.1
KEYWORDS    RefSeq.
SOURCE      Bacillus safensis
  ORGANISM  Bacillus safensis
            Bacteria; Bacillota; Bacilli; Bacillales; Bacillaceae; Bacillus.
REFERENCE   1  (bases 1 to 3801264)
  AUTHORS   Saroj,D.B. and Gupta,A.K.
  TITLE     Full genome sequence for characterization of the strain BLXSC Safety
            evaluation of the strain through multidisciplinary approach
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 3801264)
  AUTHORS   Saroj,D.B. and Gupta,A.K.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-DEC-2018) Applied Microbiology Laboratory, Advanced
            Enzyme Technologies Limited, 5th Floor, A Wing, Sun Magnetica, LIC
            Service Road, Louiswadi, Thane, Maharashtra 400 604, India
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: 25-NOV-2018
            Assembly Method                   :: MaSuRCA v. 3.2.2
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 355.0x
            Sequencing Technology :: Illumina MiSeq; Oxford Nanopore GridION
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_023524005.1-RS_2024_05_27
            Annotation Date                   :: 05/27/2024 04:40:03
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,916
            CDSs (total)                      :: 3,803
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 113
            rRNAs                             :: 9, 9, 9 (5S, 16S, 23S)
            complete rRNAs                    :: 9, 9, 9 (5S, 16S, 23S)
            tRNAs                             :: 81
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 38
            CDSs (without protein)            :: 38
            Pseudo Genes (ambiguous residues) :: 0 of 38
            Pseudo Genes (frameshifted)       :: 21 of 38
            Pseudo Genes (incomplete)         :: 20 of 38
            Pseudo Genes (internal stop)      :: 7 of 38
            Pseudo Genes (multiple problems)  :: 9 of 38
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 08:04:02
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 821301
            Orig. end                         :: 842207
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP034414.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..20906
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="RRE-containing"
                     /region_number="2"
                     /rules="minimum(1, [Bottromycin_Methyltransferase_RRE,
                     Cyanobactin_D_RRE, Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /tool="antismash"
     cand_cluster    1..20906
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /kind="single"
                     /product="RRE-containing"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..20906
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:10906](+)"
                     /cutoff="10000"
                     /detection_rule="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /neighbourhood="10000"
                     /product="RRE-containing"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..10906
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /neighbourhood="10000"
                     /product="RRE-containing"
                     /protocluster_number="1"
     gene            707..1273
                     /gene="lepB"
                     /locus_tag="EI692_RS04205"
                     /old_locus_tag="EI692_04240"
     CDS             707..1273
                     /EC_number="3.4.21.89"
                     /GO_function="GO:0004252 - serine-type endopeptidase
                     activity [Evidence IEA]"
                     /GO_process="GO:0006465 - signal peptide processing
                     [Evidence IEA]"
                     /GO_process="GO:0009306 - protein secretion [Evidence IEA]"
                     /codon_start=1
                     /gene="lepB"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008349116.1"
                     /locus_tag="EI692_RS04205"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EI692_04240"
                     /product="signal peptidase I"
                     /protein_id="WP_144469974.1"
                     /transl_table=11
                     /translation="MTTNTKTQKKKSELWGWIKAILIAFIAVFIIRNFLFAPYIVKGSS
                     MYPTLHDTERVFVNKTVDYFGDYKRGQIIVLDGEDRSTHYVKRLIGLPGDKIEMKNDQL
                     YVNGKKVAEPYLASNKKKAAADGTLLTPDFGPLTVPKGKYFVMGDNRQNSMDSRNGLGL
                     FTKRDIQGTTSFVFYPFQDIRLLNQ"
     gene            complement(1315..2610)
                     /locus_tag="EI692_RS04210"
                     /old_locus_tag="EI692_04245"
     CDS             complement(1315..2610)
                     /GO_function="GO:0016765 - transferase activity,
                     transferring alkyl or aryl (other than methyl) groups
                     [Evidence IEA]"
                     /GO_function="GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA]"
                     /GO_process="GO:0019346 - transsulfuration [Evidence IEA]"
                     /NRPS_PKS="Domain: Aminotran_1_2 (65-187). E-value:
                     8.6e-13. Score: 40.0. Matches aSDomain:
                     nrpspksdomains_EI692_RS04210_Aminotran_1_2.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) DegT_DnrJ_EryC1"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Aminotran_1_2"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Aminotran_5"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1168: O-succinylhomoserine sulfhydrylase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012009373.1"
                     /locus_tag="EI692_RS04210"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EI692_04245"
                     /product="homocysteine synthase"
                     /protein_id="WP_095408047.1"
                     /sec_met_domain="DegT_DnrJ_EryC1 (E-value: 1.8e-14,
                     bitscore: 51.6, seeds: 38, tool: rule-based-clusters)"
                     /sec_met_domain="Aminotran_1_2 (E-value: 5.5e-11, bitscore:
                     40.0, seeds: 48, tool: rule-based-clusters)"
                     /sec_met_domain="Aminotran_5 (E-value: 4.8e-10, bitscore:
                     36.7, seeds: 34, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSEERPFRLETKAIHAGQELDSATYSRAVPIYQTSSFGFRDSEHA
                     ANLFGLQEPGNIYSRIMNPTNDVFEKRIAELEGGIGALAVSSGQAATTYSILNIAGAGD
                     EIVSSSSLYGGTYNLFAHTLKKLGITVKFVDSSNLEELEAAITDKTKAVYAESIGNPKG
                     DILHIEAISAIAHKHHIPLIVDNTLASPYLLRPIEFGADIVVHSATKFIGGHGTSIGGV
                     IVDSGRFPWADSDKFKGLTEPDPSYHGLTYTEAIGEAAYITKARVQLLRDLGAALSPFN
                     SFLLLQGLETLHLRLERHSENALKTAQFLQDHPLVDWVSYPGLESHESYELAQTYLPKG
                     QGAILTFGIKGGREAGKKLIDSVKLFSHLANVGDSKSLIIHPASTTHQQLSEAEQKATG
                     VTPELIRLSVGTEAIEDILADLEQAITKSQSE"
     aSDomain        complement(2050..2415)
                     /aSDomain="Aminotran_1_2"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_EI692_RS04210_Aminotran_1_2.1"
                     /evalue="8.60E-13"
                     /label="EI692_RS04210_Aminotran_1_2.1"
                     /locus_tag="EI692_RS04210"
                     /protein_end="187"
                     /protein_start="65"
                     /score="40.0"
                     /tool="antismash"
                     /translation="NDVFEKRIAELEGGIGALAVSSGQAATTYSILNIAGAGDEIVSSS
                     SLYGGTYNLFAHTLKKLGITVKFVDSSNLEELEAAITDKTKAVYAESIGNPKGDILHIE
                     AISAIAHKHHIPLIVDNT"
     gene            2877..3032
                     /locus_tag="EI692_RS04215"
                     /old_locus_tag="EI692_04250"
     CDS             2877..3032
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008349111.1"
                     /locus_tag="EI692_RS04215"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EI692_04250"
                     /product="FbpB family small basic protein"
                     /protein_id="WP_048240183.1"
                     /transl_table=11
                     /translation="MEKKKKRKKYRKHMDITLDILIERNKYEIYSNKERIEAIYDRIDE
                     KHTRTK"
     gene            3196..3963
                     /locus_tag="EI692_RS04220"
                     /old_locus_tag="EI692_04255"
     CDS             3196..3963
                     /EC_number="7.6.2.14"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013351600.1"
                     /locus_tag="EI692_RS04220"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EI692_04255"
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_249856984.1"
                     /transl_table=11
                     /translation="MAISIDIVDKSFWKDKQSIRVLEDLRLNIIPGEFVTVIGPSGCGK
                     STLLKIISGLDTAYDGQILIGDRRVTEPGMKQGFIFQEHRLFPWLSVEENIAANFNLKQ
                     QDVRRKVDELIEIVRLKGFEHAYPHELSGGMSQRVAIARALLRDPEILLLDEPFGALDA
                     FTRKHLQDVLLDIWQEKKTTMMLVTHDIDESIYLGNEIVLMQARPGRIHKILPVNLPFP
                     RDRTSTAFQHLRQKVLSEFEKTDELLLTDGSGI"
     gene            3978..4970
                     /locus_tag="EI692_RS04225"
                     /old_locus_tag="EI692_04260"
     CDS             3978..4970
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008358665.1"
                     /locus_tag="EI692_RS04225"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EI692_04260"
                     /product="aliphatic sulfonate ABC transporter
                     substrate-binding protein"
                     /protein_id="WP_249856985.1"
                     /transl_table=11
                     /translation="MKKKQMIVIFLSLLLVLAGCDQAADGSENKVKEIRIGIQQSLSPL
                     LLAKEKGWFEQSFEKEGVKVKWVEFQSGPPQFEGLAANQLDFSQVGNSPVIAGQAAGID
                     FKEIGLSQDGLKANGILVNKNSEIQKVEDLKGKKIAVAKGSSGFDFLYKVLDQAGLSAK
                     DVQIIQLQPDEAISAFENGSVDAWSIWEPFLSLETIKKGAKLLVNGEATDLYSPGFTLV
                     RTQFADQHPELVVKFLKVYDHAVKWQKSHPEEAVTLYARLKNLDKKVVTQVLNNTEPLN
                     KPISKEIINAQQHTADFQYKTKAIQRKIDVNQVVDNSFIEKMLKEEMDE"
     gene            5060..5797
                     /locus_tag="EI692_RS04230"
                     /old_locus_tag="EI692_04265"
     CDS             5060..5797
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1044: ABC
                     transporter, permease protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010333486.1"
                     /locus_tag="EI692_RS04230"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EI692_04265"
                     /product="ABC transporter permease"
                     /protein_id="WP_249857327.1"
                     /transl_table=11
                     /translation="MVLPVLLIAVWQIIAGSQIVSSTVLPTPILIAESFRDLFRSGELF
                     GHLYISLYRAICGFLLGGGLGLLLGVCVGFSKKTEQYVDPTLQMLRTVPHLAVTPLFIL
                     WFGFDETAKILLIALGAFFPIYINTFLGIRSVDNKLFDVAHALEFNLYQSITKLILPAA
                     LPHILLGVRLSLGIAWLGLVVAELMGSSSGVGYMIMDARQFSQTDKVFVGIIIFAVVGK
                     LTDSFVRLLEKRLLKWRTSYQGE"
     gene            5815..6957
                     /gene="ssuD"
                     /locus_tag="EI692_RS04235"
                     /old_locus_tag="EI692_04270"
     CDS             5815..6957
                     /EC_number="1.14.14.5"
                     /GO_function="GO:0008726 - alkanesulfonate monooxygenase
                     activity [Evidence IEA]"
                     /GO_function="GO:0010181 - FMN binding [Evidence IEA]"
                     /GO_process="GO:0006790 - sulfur compound metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="ssuD"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1083: oxidoreductase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017360383.1"
                     /locus_tag="EI692_RS04235"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EI692_04270"
                     /product="FMNH2-dependent alkanesulfonate monooxygenase"
                     /protein_id="WP_249856986.1"
                     /transl_table=11
                     /translation="MNILWFIPTHGDGRYLGSAKGARQADYPYFKQIAQAADQLGYTGV
                     LLPTGRSCEDPWLTAAALAAETTHLKFLVALRPGLMQPSVAARMTSTLDRLSGGRLLIN
                     VVAGGSKEELEGDGLFISHDERYEAAEEFLTIWKRLLKGENVQFHGKHLQAENSRLLFP
                     PAQTPHPPVFFGGSSSAGIQTAAKHTDVYLTWGEPPAQVKEKIAQVKKQAEKEGRTVKF
                     GIRLHVIVRDTEEEAWQAAEHLIRHLDQKTIDEAQKVLQGMDSVGQRRMVELHQGRKDK
                     LEISPNLWAGIGLVRGGAGTALVGDPQTVADRIIEYQSLGIDTFIFSGYPHLEEAYYLA
                     ELVFPLLPFKRSGDTGLSVPAGEIIGNNHFPDAASAASSS"
     misc_feature    7406..7421
                     /note="TFBS match to LexA_variant_1, Repressor of DNA
                     damage response, confidence: weak, score: 23.11"
                     /tool="antismash"
     misc_feature    complement(7407..7420)
                     /note="TFBS match to LexA_variant_2, Repressor of DNA
                     damage response, confidence: medium, score: 20.49"
                     /tool="antismash"
     gene            7499..7711
                     /locus_tag="EI692_RS04240"
                     /old_locus_tag="EI692_04275"
     CDS             7499..7711
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008358673.1"
                     /locus_tag="EI692_RS04240"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EI692_04275"
                     /product="hypothetical protein"
                     /protein_id="WP_003211695.1"
                     /transl_table=11
                     /translation="MTYAAPQVDYSTMEPAIMDQAWFLVFVAVLLGLGATVVLGAAVWC
                     LANGKGSFTGAVQWESGLKVQIECK"
     gene            7827..8573
                     /locus_tag="EI692_RS04245"
                     /old_locus_tag="EI692_04280"
     CDS             7827..8573
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003211711.1"
                     /locus_tag="EI692_RS04245"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EI692_04280"
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_111291908.1"
                     /transl_table=11
                     /translation="MFTIENLTKTYKNNVTAVNDFHLKIDPHQIVAVAGPNGSGKTTMI
                     NCILGIIKHTEGRIHLQDVTNDEPSFKKQVAYVPDDLLLPEALTGAEYLDFVSSMYECK
                     TIHRRNQLIELFDMDSALSRPIETYSHGMKKKTQLIAAFMLDSQLVIMDEPFRGLDIEA
                     VINTKKLMKRYAEHHGAILLSTHDMLSAEELCHKIAIISKGNKMDEGTVSALKEKYQSS
                     TLEQVFLKASMLSDRGAHFDEIINHF"
     gene            8551..10017
                     /locus_tag="EI692_RS04250"
                     /old_locus_tag="EI692_04285"
     CDS             8551..10017
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003212365.1"
                     /locus_tag="EI692_RS04250"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EI692_04285"
                     /product="hypothetical protein"
                     /protein_id="WP_249856987.1"
                     /transl_table=11
                     /translation="MKSLIISKMMLKMWQQEMYKLFDTQTKRIIVVLFFLFAVTMGAII
                     GYSFTGVFMKAFLNGDERSLGLLVVSMAINASIFTSLLFVLIKVRTPEQDRFSMQLSWF
                     PLSTFQKSFGYFIPMVTVVTGLVLFFIGILLLPNFIAQGIGIFFIFTFFLMVLLQSLFV
                     LMLLQFIYNITYLFVLKLKLPLQKFAAIFVLLALVVAYGLTHFDISQIQQSYIQFDYHL
                     MYFTAPFFLAGQGMAPEGVNYAVLILFILLSAGGAFLSLAMMPIMAEKKALTFLHKLPF
                     SSSKKWSLIVKEMKSQVRNEENILNFLILLIVILFVRYQFGFRFEEEAFFVLCALAGLT
                     AFNSFGNDKRMLGMYKTFGLRSWEVALYKFIGLLLVGVLQIVLFMLTTLTLPDQIWHVL
                     IGAAVLCNATALFYVVGILLPLDRNNPYTGIFSFGALILLMIPIVFIGNYVIGASSQAL
                     QWLLVAAFEGLLIFAIYKGFSWRYSHDSTS"
     gene            10001..10906
                     /locus_tag="EI692_RS04255"
                     /old_locus_tag="EI692_04290"
     CDS             10001..10906
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RRE-containing: PqqD_RRE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF05402"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019743967.1"
                     /locus_tag="EI692_RS04255"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EI692_04290"
                     /product="PqqD family protein"
                     /protein_id="WP_249856988.1"
                     /sec_met_domain="PF05402 (E-value: 1.4e-07, bitscore: 29.5,
                     seeds: 461, tool: rule-based-clusters)"
                     /sec_met_domain="PqqD_RRE (E-value: 1.2e-09, bitscore:
                     35.6, seeds: 9, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIQLLNNKLKIERVPALAPYVTLQKRHLTDTQYGSTLPINESAYH
                     MLTKVDGKRTEASITAELADLFQVDESVIARDFYQLMRGLNQHHLLSIHYHSPYRIVTA
                     CCQFFKQYQVKMKERFDCTGHSFLHIFGTALLMVTRKIIFFWMLFMVMAGIAFLFIPDP
                     SIAAIAIYFTIIYFGLITGTALHEAAHGYAHRKFAGRDGPQGFFASDMMSVKFVRPVLD
                     PFQKKQVWITLLGPLVPGVIGAAGIVVTILFLKENPVSTAFFIFSITYFIQLLYLLPFM
                     GDGKSIMKQLLLGGMGGQRS"
     aSDomain        10109..10276
                     /aSDomain="PqqD_RRE"
                     /aSTool="RREfinder"
                     /database="RREFam.hmm"
                     /description="RRE-containing protein in a pyrroloquinoline
                     cluster"
                     /detection="hmmscan"
                     /domain_id="rrefinder_EI692_RS04255_PqqD_RRE.1"
                     /evalue="8.80E-12"
                     /identifier="RREFam006.1"
                     /label="EI692_RS04255"
                     /locus_tag="EI692_RS04255"
                     /protein_end="92"
                     /protein_start="36"
                     /score="35.6"
                     /tool="antismash"
                     /translation="LPINESAYHMLTKVDGKRTEASITAELADLFQVDESVIARDFYQL
                     MRGLNQHHLLS"
     gene            10903..11184
                     /locus_tag="EI692_RS04260"
                     /old_locus_tag="EI692_04295"
     CDS             10903..11184
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003211021.1"
                     /locus_tag="EI692_RS04260"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EI692_04295"
                     /product="hypothetical protein"
                     /protein_id="WP_048240191.1"
                     /transl_table=11
                     /translation="MNVQAMKQGAIVGSFLGFLGFPMLTIGVLFYHLFQSKTNDALLFN
                     SLAFEMEGSSAFTFQIKPNFFIYMIVIFAASFLIVAFLSAMKQKKAKG"
     gene            11264..11920
                     /locus_tag="EI692_RS04265"
                     /old_locus_tag="EI692_04300"
     CDS             11264..11920
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017360379.1"
                     /locus_tag="EI692_RS04265"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EI692_04300"
                     /product="hypothetical protein"
                     /protein_id="WP_205182917.1"
                     /transl_table=11
                     /translation="MFKKWSILIFTVFLLAGCGEKDEETTTTEKTVSTIKTEPATKNQV
                     TIEQMKLSKKEKNLLEAATTNEKVALTLKGLTKKNKSITFIGNHYKNGRLVNKEASSAT
                     FTLHQNGTDQTVNVLLQLHHEKDTYESQFSMWSDKKNDGMTKATSSFPFKVSDYVFSAQ
                     SETVKVASGGKALIAYTAAMGKDGNSPLIEEIQKNPKQALKNKSHASLFYIQLDK"
     tRNA            12048..12121
                     /anticodon=(pos:833381..833383,aa:Gly,seq:tcc)
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /locus_tag="EI692_RS04270"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /old_locus_tag="EI692_04305"
                     /product="tRNA-Gly"
     gene            12048..12121
                     /locus_tag="EI692_RS04270"
                     /old_locus_tag="EI692_04305"
     gene            complement(12220..12816)
                     /locus_tag="EI692_RS04275"
                     /old_locus_tag="EI692_04310"
     CDS             complement(12220..12816)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017360378.1"
                     /locus_tag="EI692_RS04275"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EI692_04310"
                     /product="hypothetical protein"
                     /protein_id="WP_240193748.1"
                     /transl_table=11
                     /translation="MKIHMEISHPQNPSIHVGQIEYSHIEVGTSPQMLKGRLRLFQESL
                     FFEYEDKVLEEVPAIKEWTDILKDVPFLPLLSDIQKEQFIDSTNSVQDLSIFFSLKYFL
                     PILTLDADRIKGPLSLAKHEAGHIEWQDGAGLNGLFSQASKAQISQDTKNILQIILFPP
                     SISREKSEALIQSLTKMFVQIHGGESKYELIEKAL"
     gene            12900..14048
                     /gene="queG"
                     /locus_tag="EI692_RS04280"
                     /old_locus_tag="EI692_04315"
     CDS             12900..14048
                     /EC_number="1.17.99.6"
                     /GO_function="GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA]"
                     /GO_function="GO:0052693 - epoxyqueuosine reductase
                     activity [Evidence IEA]"
                     /GO_process="GO:0008616 - queuosine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="queG"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003211063.1"
                     /locus_tag="EI692_RS04280"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EI692_04315"
                     /product="tRNA epoxyqueuosine(34) reductase QueG"
                     /protein_id="WP_041816180.1"
                     /transl_table=11
                     /translation="MHVGELKEELIQYAKEIGVDKIRFASADTFDSLKDRLILHESLGY
                     LSGFEEPDIEKRTNPSLLLPKAKSIVAIALAYPSKMKDAPRSTKDARRGIFCRASWGTD
                     YHVVLKKKLDMLEEFLRSKHVDIRTKSMVDTGELSDRAVAERAGIGFSAKNCMIITPEF
                     GSYVYLAEMITNVPFEPDEKIEDQCGTCNKCVDSCPTGALVNPGQLNSQRCISFLTQTK
                     GFLPDEFRSKIGNRLYGCDTCQIVCPINKGKDFHLHPEMEPDPEIAKPLLKPLLTISNR
                     EFKEKYGHVSGSWRGKKPIQRNAILALAHFKDTSALPVLIELMHKDPRPVIRGTAAWAI
                     GKIGDDQQLPELEKALERESDEEAKEEIVKGIELLQTPLNTK"
     gene            14110..15012
                     /locus_tag="EI692_RS04285"
                     /old_locus_tag="EI692_04320"
     CDS             14110..15012
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008358689.1"
                     /locus_tag="EI692_RS04285"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EI692_04320"
                     /product="amidase domain-containing protein"
                     /protein_id="WP_095408671.1"
                     /transl_table=11
                     /translation="MKQLLEKTLEDRLAYLINDRAIKQPQLMSDVEAVERKKELFARRQ
                     VEIVKAKAKTKLLDSAIQDDGAQHVQYLAHLTYVCKDVDDSFYLEEQVEKREAFLYNDM
                     LVKDRMMLEERQREELMDERFQTEEQFGRAFHYDRRAAVQYAETYWNKRNPAYKNFEDN
                     CTNFISQCLKAGNAPTRGYPNRGSGWWVRPHTWSYSWTVAHSMKNYLANSKAGLRAKKL
                     KEAHELQIGDVICYDFEGDGRYNHTTIVVDHDKGGMPLVNAQTYDCRMRYWSYEDSTAY
                     TPAIRYMFFHILDDAAKDS"
     gene            15056..15529
                     /gene="trmL"
                     /locus_tag="EI692_RS04290"
                     /old_locus_tag="EI692_04325"
     CDS             15056..15529
                     /EC_number="2.1.1.207"
                     /GO_function="GO:0008175 - tRNA methyltransferase activity
                     [Evidence IEA]"
                     /GO_process="GO:0006400 - tRNA modification [Evidence IEA]"
                     /codon_start=1
                     /gene="trmL"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003211950.1"
                     /locus_tag="EI692_RS04290"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EI692_04325"
                     /product="tRNA (uridine(34)/cytosine(34)/5-
                     carboxymethylaminomethyluridine(34)-2'-O)-
                     methyltransferase TrmL"
                     /protein_id="WP_034282301.1"
                     /transl_table=11
                     /translation="MGLHVVLYQPEIPANTGNIARTCAATNTTLHLIRPLGFSTDDKML
                     KRAGLDYWKYANVVYHDSLDELFEAHPKGQFFYITKFGQKPHTTFDYSQLDEDYFFVFG
                     RETSGLPKDLIEQNMDRCLRLPMTEHVRSLNLSNTAAILVYEALRQQQYRDLI"
     misc_feature    15874..15892
                     /note="TFBS match to FuR_variant_2, Ferric Uptake
                     Regulator, confidence: weak, score: 23.8"
                     /tool="antismash"
     gene            16005..17900
                     /locus_tag="EI692_RS04295"
                     /old_locus_tag="EI692_04330"
     CDS             16005..17900
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_388778.1"
                     /locus_tag="EI692_RS04295"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EI692_04330"
                     /product="PrkA family serine protein kinase"
                     /protein_id="WP_111291904.1"
                     /transl_table=11
                     /translation="MDILKKIEQHREEEQRLKWEGTFSDYLDIIKENPLVAQSAHSRVY
                     HMIKDSGIEEENGVRTYKFFDQELFGLEESLERLVEEYFHPAAKRLDVRKRILLLMGPV
                     SGGKSTLVTRLKRGLEEYSLTDHGAVYAIKGCPMHEDPLHLIPQNLREDFYREYGIRVQ
                     GNLSPLNMMRLEEEYGGRIEDVRVERIFFSEDKRTGIGTFSPSDPKSQDIADLTGSIDF
                     STIAEFGSESDPRAYRFDGELNKANRGMMEFQEMLKCDEKFLWHLLSLTQEGNFKAGRF
                     ALISADELIVAHTNETEYRSFISNKKNEALHSRIIVMPIPYNLKVTEEERIYYKMISES
                     DVSDVHIAPHTLKVAAMFSILTRLKEPKRSDIDLVKKMRLYDGESVEGFQSVDIDEMKK
                     EFHDEGMSGIDPRYVINRISSTIIRKNMESINALDVLRSLKEGLDQHPSISSEDRERYL
                     NFISVARKEYDDIAKKEVQKAFVYSYEESAKTLMDNYLDNVEAYCNKNKLRDPLTGEEM
                     NPDEKLMRSIEEQIGISENAKKAFREEILIRISAYARKGKRFDYNSHERLREAIQKKLF
                     ADLKDVVKITTSTKTPDEQQLKKVNEVVARLIDEHGYNSTSANELLKYVGSLLNR"
     gene            18040..19203
                     /gene="yhbH"
                     /locus_tag="EI692_RS04300"
                     /old_locus_tag="EI692_04335"
     CDS             18040..19203
                     /GO_function="GO:0003674 - molecular_function [Evidence
                     IEA]"
                     /GO_process="GO:0030436 - asexual sporulation [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="yhbH"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019743973.1"
                     /locus_tag="EI692_RS04300"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EI692_04335"
                     /product="sporulation protein YhbH"
                     /protein_id="WP_034282299.1"
                     /transl_table=11
                     /translation="MSRQEKSQFIVSQEDWSLHRKGYDDQQRHQKKVKEAIKNNLPDLV
                     TEESIIMSNGKDVVKIPIRSLDEYKIRYNYDKNKHVGQGDGDSEVGDVVARDGSDSKQG
                     QGKGQGAGDQAGEDYYEAEVSLMDLEEALFRELELPNLKQKELDDIIVEQIEFNDIRKT
                     GLTGNIHKKRTMLSAFKRNAMTGSPSFYPIYPEDIKYKTWNEVTKPESKAVVLAMMDTS
                     GSMGLWEKYMARSFFFWMTRFLRTKYETVDIEFIAHHTEAKVVDEEHFFSRGESGGTIC
                     SSVYRKALELIDERYPPSRYNIYPFHFSDGDNLTSDNARCVKLVSEIMKKANLFCYGEV
                     NQYNRHSTLMSAYKHIQDEKFKHYILKQKSDVFLALKKFFQQEEVHS"
     gene            19569..20201
                     /locus_tag="EI692_RS04305"
                     /old_locus_tag="EI692_04340"
     CDS             19569..20201
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1029: RND family
                     efflux transporter MFP subunit"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003211200.1"
                     /locus_tag="EI692_RS04305"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EI692_04340"
                     /product="HlyD family efflux transporter periplasmic
                     adaptor subunit"
                     /protein_id="WP_087978746.1"
                     /transl_table=11
                     /translation="MNRGRLLLTNIIGLIVILAIIAGGAYYYYESTNFVKTDEAKVTGD
                     MYQITAPAAGQIKGWDINEGDEVEKDSTVAKVEGQTKTNIKAVADGTLVKKEVQNNQQV
                     QPGTVLGETIDLSKLYITANIKETDIKNIEKGDKVDIVVDGDPDTTFEGNIEQIGYATN
                     STFNMLPATNSSGNYTKVTQKVAVKISIKNPSDKVLPGMNASVKISS"
ORIGIN
        1 gactcagtca ttttattata tggtgaccat aacggtattt ctgagaacca taaccgtgca
       61 atgagtgaaa ttcaagggaa agaaatcact ccttatcaaa atgcacaaaa ccagcgtgtt
      121 ccgctcatga ttcgtatccc tggtaaacag ggcggcgtga accatacgta tggtggtgaa
      181 gtcgacgtta tgccaacact tcttcactta caaggtatcg attcaaatga attcgtgaat
      241 tttggaacag acctattctc taaaaagcat gatcagaccg ttgccttccg taatggaaac
      301 tatgtgacac cgaaatatac acttgtcgat aataccgttt atgatacgaa aacgggtaaa
      361 gtggtgaaac aaaataaaaa gacagaggcg attaaagccc gtgttgataa tcagttaagt
      421 ctttcagata aagtgctcta cagggatctt cttcgattcc ataagttatc tgatttcaaa
      481 ccagtgaatc catcggatta tttctatggt aaagcaaaca aagaaaaaga agcggattct
      541 tctgctaact aactgagttt tgggcaagca cagaaaggtg cttgcctttt tctctctcat
      601 tgcttgattt gttggcaaaa tatgtttata tttagggaga aacaagtgtg atgccggctg
      661 acgctggtga cacacatttc gtccttgggg aattcaggag gagcttatga caacaaatac
      721 aaaaacacaa aaaaagaaat cagaattatg gggctggatc aaagccatct taatcgcatt
      781 tattgctgtt tttatcatcc ggaacttttt attcgcgcca tacattgtca aaggatcttc
      841 tatgtatccg acattgcatg atacagagcg ggtgtttgtg aataaaacag ttgattattt
      901 cggtgattat aaacggggcc agatcattgt tcttgatggg gaagaccgca gcacccatta
      961 tgtcaaacga ttgattggtt tacctggtga taaaattgaa atgaaaaatg atcagctata
     1021 tgttaatgga aaaaaagtgg cggagcctta cttagcgtca aacaaaaaga aagcagctgc
     1081 agatggcact ttgctgacac ctgattttgg tcctcttact gttccaaaag gaaagtactt
     1141 tgtcatgggg gacaatcgcc aaaattcaat ggacagccgc aacggcttag gtctttttac
     1201 aaagcgtgat attcaaggaa ctacctcatt tgtattttat cctttccaag acattcgatt
     1261 actcaatcaa taataaacaa taaaaaagca cacagctgtg tgcttttttc tatgtcattc
     1321 agactgactt tttgtaatcg cctgttcaag atctgcaaga atatcttcaa tcgcttctgt
     1381 cccaacagat aaacgaatga gctctggtgt gacacctgtt gctttttgtt ctgcctcact
     1441 taattgttga tgcgttgtgc tggcaggatg aatgatgaga gatttagaat cgcccacgtt
     1501 tgctagatgg gagaaaagct tcacagaatc aatgagcttt ttacctgctt cgcgtccacc
     1561 tttaataccg aatgtgagga tcgcgccttg tccttttggt aaataggttt gagcaagctc
     1621 ataggattcg tgactttcaa ggcccggata gcttacccaa tcgacaagag gatgatcctg
     1681 taagaattgt gctgttttca aagcattttc actatgccgc tcaagacgaa ggtgtaatgt
     1741 ttctaaacct tgcagaagta aaaatgagtt gaatggcgac agagctgccc ctaaatcacg
     1801 taagagctgt actcgtgctt ttgtgatata agccgcttct ccaattgctt ctgtatatgt
     1861 cagcccgtga tagcttggat ctggttcagt cagccctttg aacttatcgc tgtcagccca
     1921 agggaatcgg ccgctatcaa cgatgacacc gccaattgat gtaccatgac cgccaataaa
     1981 tttcgtcgct gagtggacaa caatgtcagc accgaactca ataggtctta ataaataagg
     2041 gctggcgagt gtgttgtcca caataagcgg gatatgatgc ttgtgtgcaa tggctgagat
     2101 ggcttcaata tgtaaaatgt cgccttttgg attcccaatg ctctctgcat acactgcctt
     2161 tgttttgtct gtgatcgctg cttcgagttc ttctaggttg gatgaatcga cgaattttac
     2221 tgtaattcca agttttttga gtgtatgggc aaataaattg taggtgccgc cataaagact
     2281 gcttgaggaa acgatttcat ctccggctcc tgcaatgttt aaaatagaat aagtcgtcgc
     2341 tgcttgtcca gaagaaacag caagtgcacc aattccacct tcaagctcag cgatacgctt
     2401 ttcaaatacg tcatttgtag ggttcataat acgtgaataa atatttcccg gttcctgaag
     2461 accaaataaa ttcgctgcat gctcactatc tctaaaacca aaggagctcg tttggtaaat
     2521 aggcacggct cttgaatagg tcgctgaatc aagctcctga cctgcgtgaa tggcttttgt
     2581 ttctaaacga aatggacgtt cttctgacat gagtgtatcc tccttttgtt agataaaacc
     2641 aactgttttg ataagaaata tttaataaga ctataaatct tgttccttgc ttggtcaatc
     2701 attttttaga taaatctgaa aaaacaataa atatagttga caggtaggaa tagtgtgtat
     2761 taacatgagc atactgaaaa cacgaacaag aatggctgat cggtcaaccg aaggctctat
     2821 cactcaaata tgagtgaaga gccttttttt tatttgaatg agaaaggatg atgaagatgg
     2881 aaaaaaagaa aaaacgaaaa aaatacagaa aacatatgga tatcacacta gacatattga
     2941 ttgagcgcaa caaatatgag atttacagta acaaggaacg aatagaagcg atttacgatc
     3001 gaatcgatga aaagcataca aggacaaaat aaccatttta taaaattgag ttgatttata
     3061 tgattagtat gatttaggat ggtgctaaca aatcaatatg attagctgat cggacaacgc
     3121 gaaggctctt atctcttttt tgggataagg gcctttctgt gtatttatct gatcgcaaga
     3181 ggagtggagg tttctatggc gatttcaatt gatattgtgg ataaatcctt ttggaaagac
     3241 aaacagtcca ttcgggtact tgaagactta agattgaaca tcattcccgg ggaatttgta
     3301 acagtgatag gtccaagtgg atgcgggaaa agtacattgc taaagatcat aagcgggctc
     3361 gacacagcgt atgatgggca aattttgata ggagacagac gggttacaga accaggaatg
     3421 aaacagggct ttatctttca ggaacaccgc ctgtttccat ggctgtcagt cgaagaaaac
     3481 atagcagcca atttcaattt aaaacaacag gatgtacgcc gtaaagtgga tgaattgatt
     3541 gaaattgttc gattaaaagg atttgaacat gcttatccac atgagctttc aggaggaatg
     3601 tcacaacggg tcgccattgc gagagcactc cttcgtgatc cggagatctt attgcttgat
     3661 gaaccatttg gtgcgctgga tgcattcaca cgaaaacact tgcaggatgt gctgctggac
     3721 atttggcagg agaaaaaaac aacgatgatg ctcgtaactc atgatattga tgaatcgatt
     3781 tatttaggaa atgaaattgt gctaatgcaa gcgagacctg gccgaatcca taaaattctt
     3841 cctgtaaatc taccttttcc gcgtgataga acgtcaaccg cttttcaaca tttaagacaa
     3901 aaggtgcttt cagaatttga gaaaacagat gaattgttac taactgatgg atcagggatt
     3961 tagggagggg aaatcgcatg aaaaagaaac aaatgatcgt gatctttttg agtcttctac
     4021 ttgttttagc aggatgtgat caagcagcag acggctcgga aaacaaggtg aaagaaattc
     4081 ggattggaat tcagcaaagt ttgagcccgc tgcttttagc aaaggaaaaa ggttggtttg
     4141 aacaatcatt tgaaaaagaa ggagtgaagg taaagtgggt ggagtttcaa agtggtcctc
     4201 cccaatttga aggacttgct gcaaatcaat tagatttctc gcaagttgga aactcacctg
     4261 tcatagcagg tcaggcagca ggcattgatt ttaaggaaat tggtttatct caggatgggc
     4321 tgaaagcgaa cggtatttta gtgaataaga acagtgagat tcaaaaagta gaagacttaa
     4381 aagggaaaaa aatcgctgtc gctaaaggga gcagtggctt tgacttttta tacaaagtat
     4441 tagatcaggc agggttatct gcgaaggatg ttcagattat tcagcttcag ccagatgaag
     4501 cgatatcagc atttgaaaat ggatccgttg atgcttggtc gatctgggag ccgttcttat
     4561 cacttgaaac gatcaagaaa ggagcaaagc tgctggtgaa tggggaagcg actgatttat
     4621 attctccagg tttcacactt gttcgcactc agtttgctga tcagcatcct gaactagtgg
     4681 tgaaattttt aaaggtatat gaccatgcgg tgaagtggca gaaatcacat ccagaagagg
     4741 ctgttactct atatgcgcgt ttaaaaaatt tagataagaa ggtcgtcaca caagtattaa
     4801 acaatacgga accactcaat aagcccattt cgaaggagat catcaatgct cagcagcata
     4861 ccgctgattt tcaatataaa acaaaggcga tccagcggaa aatagatgtc aatcaggttg
     4921 tagataattc gtttattgaa aaaatgctga aagaggagat ggatgaatga aagctatttc
     4981 gaatccagct ttagcatcta aaatcgagcg gacaaagaaa aaaaggagaa aagcttcttc
     5041 tttatataag ttaaagggaa tggtattacc tgttctactt attgcggttt ggcagatcat
     5101 agccggttct caaatcgttt cttccactgt acttcctacg cctatcttga ttgcagaatc
     5161 ttttcgagat ttatttcgtt ctggtgaact gtttggtcat ctttacatca gcctttatcg
     5221 agcgatatgt ggatttttac ttgggggtgg tttaggtctt ttgctgggcg tatgcgtagg
     5281 gttttctaaa aaaacagagc agtatgtaga tccgacgttg caaatgttga gaaccgttcc
     5341 acatttagcg gtcactcctt tatttatcct ctggtttggc tttgatgaaa cggcgaaaat
     5401 tttattgatt gcacttgggg ctttttttcc gatttatatt aatacttttc taggtattcg
     5461 cagtgtagat aataagctgt ttgatgtggc tcacgcctta gagtttaatc tgtatcaaag
     5521 catcacaaag ctgattttac cggctgctct tcctcatatt cttctgggcg tgaggctgtc
     5581 attaggaatt gcttggcttg gactagtggt agctgagttg atgggttcaa gcagcggcgt
     5641 cggctatatg attatggatg caaggcaatt ctctcaaacg gataaagtgt ttgtaggaat
     5701 tatcatcttt gcagtagtag gtaagctgac agattcattt gtacgtctgt tagaaaagcg
     5761 tctgctcaag tggcgcacta gttatcaagg tgaataataa cagggggcga tgtcatgaat
     5821 attttatggt ttattccaac gcatggagac ggccgttatt taggttcagc gaaaggggca
     5881 agacaggcag actatccata ttttaaacaa attgctcaag ctgctgatca gcttgggtat
     5941 acaggggtct tgctgcctac tgggagatca tgtgaagatc catggctgac ggcagctgct
     6001 ttagctgctg aaacaactca tttaaagttc ctcgtggctc ttagaccagg gctgatgcag
     6061 ccgtctgttg ctgctagaat gacttctaca ttggatcgtc tttcaggtgg gaggctgctg
     6121 attaatgtgg tagcaggggg aagtaaagag gagcttgaag gggatgggct gttcatttct
     6181 catgatgaac gctatgaggc agcagaagag tttttgacga tttggaagcg gttattgaaa
     6241 ggagaaaatg tacaatttca tggcaaacat ctacaagcgg agaatagccg gctgttattc
     6301 ccaccagctc aaacacccca tccaccagtc ttttttggcg gatcatcatc agcaggaatt
     6361 caaacagccg ccaagcatac agatgtttat ttaacttggg gcgaaccgcc tgcacaagta
     6421 aaagagaaaa ttgctcaagt gaagaaacag gctgaaaagg aaggaagaac ggtgaagttt
     6481 ggcattcgtc ttcatgtgat cgtgagagat accgaagagg aggcatggca ggcagcggaa
     6541 catctgattc gtcatttgga tcaaaaaaca attgatgagg cgcaaaaagt gttacagggg
     6601 atggactcag taggtcaaag acgaatggtg gaattgcacc aagggaggaa agacaaactt
     6661 gaaatcagcc caaatctttg ggcaggcatt ggtttagtac gcggcggtgc aggaacagca
     6721 cttgtcggag acccgcaaac agtagcagat cgtatcatag aataccagtc tctaggcatt
     6781 gatacattta tattttctgg atacccgcac ttagaagaag cttattattt agcagagctt
     6841 gtttttccgc tccttccatt caagagatca ggagatacag gactctctgt gccagctggt
     6901 gaaatcattg ggaacaatca ttttccagat gcagcctctg ctgctagttc ctcataaata
     6961 tgaaaagcaa agcagtctac gggtggctgc tttgcttttt ttcatagaaa ggagcgagtc
     7021 atatgttgtg tgctgctgaa aaaaggcaag ggcttttttc ccaatcgatt ttcttgtata
     7081 tacatatttt cagagccaag agaagaagga aaatatgctc actcttttat cggaattatc
     7141 agtaaatatt tcataattga cgttattgcg acatataatc aggactttta tatctgatat
     7201 atcgggggaa ttcttgctat ctcacaaaaa agaaagaaca tatatcacag atgataaata
     7261 tgaactattt caaaaaagaa agaaaaaaga tggtcgaatt gacattatat gggttttgtg
     7321 gttcttatgg ggtgtcaaaa tctagtaaat aagagagggt ttgagcggtt taaagtgaat
     7381 aattgaataa aaagtcacat tttaatcaaa tgtatgttcg gtcaaaaatg ggatgttctg
     7441 tagatgtttg gagtgtgacg cctatgatac gatcatcata agctgggagg tgaaaagtat
     7501 gacttatgca gcgccgcaag ttgactattc cactatggaa cctgctatta tggaccaagc
     7561 ttggttctta gtatttgttg ctgtccttct tggattggga gcaacagttg ttctaggagc
     7621 agcagtttgg tgtttagcaa acggcaaggg tagctttaca ggagccgttc agtgggaaag
     7681 tggcttaaaa gtccaaattg aatgtaagta gctatactta ggattcatct ttttacttct
     7741 tagataagac atcagggcta aaccgtctgt ggcgggcggt ttagcctgat ctgtttttaa
     7801 agaatatgca gacacttgga ggttatatgt ttacgatcga gaatttaacc aagacgtata
     7861 aaaataacgt gactgctgtc aatgattttc atttaaagat cgaccctcat caaatcgttg
     7921 ctgtagctgg accgaatggt tcgggtaaaa caacgatgat taactgtata ctcggcatta
     7981 ttaagcatac agaaggaagg attcacttgc aggacgtcac aaatgatgaa ccatccttta
     8041 aaaaacaagt agcctatgtt ccagatgacc tgctgctccc tgaagcattg actggtgctg
     8101 aatatttaga ttttgtttct tctatgtatg aatgtaaaac aattcacaga agaaatcaac
     8161 taattgaact gtttgatatg gactcggcct tatcaagacc gatcgaaact tattcacatg
     8221 gtatgaaaaa aaagacacag ctgattgctg catttatgct tgatagtcaa ttggtgatca
     8281 tggatgagcc ctttagagga cttgatattg aagcggttat aaacacaaag aaactgatga
     8341 agcggtatgc cgagcaccat ggtgcgatct tgctttcaac gcatgatatg ctttcagcgg
     8401 aagagctgtg ccacaaaatc gccattattt ctaaaggaaa taaaatggat gaaggaacgg
     8461 tctcagcctt aaaggagaag tatcaatcaa gcacactgga acaggtgttt ctgaaagctt
     8521 caatgttaag tgataggggt gcacattttg atgaaatcat taatcatttc taaaatgatg
     8581 cttaaaatgt ggcagcagga gatgtataag ctctttgata ctcaaacgaa gcggatcatt
     8641 gtggtcttat tctttttgtt tgccgtcaca atgggagcca ttatcggata cagctttact
     8701 ggtgtcttta tgaaggcttt cttaaatgga gatgaacgtt cactcggatt actcgtcgtg
     8761 tcaatggcga ttaatgcctc catttttaca agcttgttat tcgttttgat caaggttaga
     8821 acacctgaac aagaccggtt ttctatgcag ctcagctggt tcccgctctc tacctttcag
     8881 aaaagttttg gttacttcat tccgatggtg acagtagtga cagggcttgt tttatttttt
     8941 atcggcattc tgcttttacc taattttatt gcccagggaa ttggtatttt ctttatcttt
     9001 actttctttt tgatggtgct tttgcagtcg ctttttgtct taatgctgct gcagtttatt
     9061 tacaatatta cttatttgtt cgttctgaaa ttaaaattac cgttgcaaaa atttgcagcg
     9121 atatttgttt tattggcact ggtagtggca tatggattga cgcactttga tattagccaa
     9181 attcagcaat catatataca gtttgattat catttgatgt attttacagc tccgtttttc
     9241 ctagcaggac aaggaatggc tcctgaaggg gtaaattatg ccgtcttgat tctgttcatc
     9301 ctcttatcgg caggcggcgc atttctttct cttgcgatga tgccgattat ggcagagaaa
     9361 aaagcgttaa cctttttaca caaactgccg ttctcttctt cgaagaagtg gtcacttatt
     9421 gtgaaggaaa tgaagtcaca ggtgcgaaat gaagaaaata ttttaaattt tcttattctc
     9481 ctcattgtga tcttattcgt ccgttatcag tttggattcc gatttgaaga agaagcattt
     9541 tttgttctat gcgctcttgc tggattaaca gccttcaatt cgtttggcaa tgataaacga
     9601 atgctgggga tgtataaaac atttggcctg agatcgtggg aagtagcttt gtataagttt
     9661 atcggccttc tgctcgttgg tgtactgcaa attgttttat tcatgctgac aacgctgacg
     9721 cttcctgatc agatttggca cgtattgatt ggtgccgctg tcttatgcaa tgccactgcg
     9781 cttttttatg tggtaggtat tttacttcct cttgatcgaa acaatcccta cacaggcatt
     9841 ttttcatttg gagcgcttat tttactcatg attccgattg tttttattgg gaactatgtc
     9901 ataggggcgt ctagtcaagc gcttcagtgg ctgcttgtgg ctgcatttga gggtctgctc
     9961 atctttgcca tatacaaagg tttttcatgg aggtattcac atgattcaac ttcttaacaa
    10021 taagctaaag attgagcggg tgccggcact agcgccgtat gtgaccttac aaaagaggca
    10081 tctcacggat acgcagtatg gaagcacact cccgatcaat gaaagtgcct atcatatgtt
    10141 aacgaaagtg gatggtaaaa gaacagaagc gagtattacc gcagagctcg ctgatttgtt
    10201 tcaggtcgat gagtcggtga ttgctcgtga cttttatcag ctgatgaggg gattgaatca
    10261 gcatcacttg ctgtctattc attatcattc accatatcgg attgtgacag cctgctgtca
    10321 atttttcaag cagtatcaag tcaaaatgaa ggaacgattt gattgcactg gtcactcgtt
    10381 ccttcacatt tttgggacgg ctttgctcat ggtgacgcgt aaaatcatct ttttctggat
    10441 gcttttcatg gtcatggcag ggatcgcttt tttattcatt cccgatccgt cgattgcagc
    10501 cattgcgatt tattttacga ttatttattt cgggttaatt accgggaccg ctttacatga
    10561 agcggcacat ggctatgcgc atcgaaaatt tgcagggcga gatggtcctc aaggcttttt
    10621 tgcgagtgac atgatgtcag tgaaatttgt aagacccgta ttagatccat ttcagaaaaa
    10681 gcaggtatgg attacactgc ttggaccgct cgttcccggt gtgattggcg cagcaggcat
    10741 cgttgtgacc attttatttc taaaagaaaa cccggtttcg accgcttttt tcattttttc
    10801 aatcacgtat tttattcaat tactctatct tcttccgttt atgggggatg gtaagtccat
    10861 tatgaagcag ttattgcttg gaggaatggg aggacaacga tcatgaacgt acaggcgatg
    10921 aaacaaggcg cgatagttgg tagttttcta gggttcttag gctttccaat gctgacaatc
    10981 ggcgtactgt tctatcattt atttcaatca aaaacgaatg atgctttatt atttaacagt
    11041 ctcgcttttg agatggaagg ctcgtccgcg tttacttttc agatcaagcc aaactttttt
    11101 atttatatga ttgtgatttt tgctgcgagt tttctcattg tggcattcct atcagctatg
    11161 aaacagaaaa aagcaaaagg ttaggagaat tctcctaatc ttttttgtat gatcaaccaa
    11221 atttttgtat aataagaaat aaaaaacatc aaaggggatc acaatgttta aaaaatggag
    11281 cattcttatc ttcacagttt ttctattagc aggatgcggc gagaaggacg aagaaaccac
    11341 gacaaccgaa aagacggttt cgacaataaa aacagagcct gccactaaaa accaagtaac
    11401 catcgaacaa atgaaactct caaaaaaaga aaaaaactta ctagaagcag caacgactaa
    11461 tgaaaaggtg gctctgacac tgaaaggatt aacgaagaag aataagagta ttacgtttat
    11521 cgggaatcat tataaaaatg gacgattagt gaataaggaa gcatcatctg ctacctttac
    11581 tttacaccag aatggaaccg accaaacggt gaatgtactt cttcaattac atcatgagaa
    11641 agatacatat gaatcacaat ttagtatgtg gtcagataaa aagaatgatg gaatgacgaa
    11701 agcgacatca agcttcccgt tcaaagtaag tgactatgta ttttctgcac aatctgaaac
    11761 tgtcaaagtt gcttctggag gaaaggcgct gattgcgtat acagcggcaa tggggaagga
    11821 tggaaattca ccattgattg aggaaattca gaagaatcca aagcaagcgc tgaaaaataa
    11881 gtcacatgca tccttatttt atatccagct agataaataa ctatcgtaat atatacggag
    11941 aatatgaagt tttttgacga aaaatcttca tattctcttg acgaattgtt aagaaagttg
    12001 taacataata aaagtcaacg cgatgacgtt gcttttaaaa gattgatgcg ggtgtagttt
    12061 agtggtaaaa cctcagcctt ccaagctgat gtcgtgagtt cgattctcat cacccgctcc
    12121 aatacataat tttgtttata acgcagtatt tcgtttctta gataaacgaa gtgttgcgtt
    12181 ttttattatg tcagtataat gtgaaaaagc actgtcaggc tacagtgctt tttcaatgag
    12241 ttcatatttg ctttctccgc catgtatttg tacaaacatc ttcgtcaagg attgaataag
    12301 agcttcactc ttttcccggg aaatagatgg cgggaaaagg atgatttgaa gaatgttctt
    12361 tgtgtcttga gaaatttgtg ctttacttgc ttgagaaaat aatccattca atcctgcgcc
    12421 gtcctgccat tcgatgtgac cagcctcatg ttttgccagt gatagcggtc cttttatgcg
    12481 atcggcatct aatgtcagga tgggtaagaa atattttagt gagaaaaata tcgacaaatc
    12541 ctgtacggaa ttggtcgagt caataaattg ttccttttgg atgtcagaaa gaagtggaag
    12601 gaaaggaacg tcttttaaaa tatccgtcca ttctttgatt gctggtactt cttctaagac
    12661 tttatcttcg tattcaaaaa ataaagattc ttgaaacagg cgtaagcggc cttttaacat
    12721 ttgaggtgat gtacccactt caatatgcga atattcaatc tgtccaacat ggatagacgg
    12781 gttttgagga tgagaaattt ccatatgtat cttcacagtg actcactcca atcggtcatg
    12841 atacactcgt attatactga aaacaacaga agaaacaaag aaaggaggtt tgcaaggtga
    12901 ttcatgttgg agaattaaaa gaagaattga ttcaatatgc gaaagaaatt ggtgtcgata
    12961 aaattcgttt tgcaagtgcc gatacatttg attcattaaa ggaccgcctc atcttacatg
    13021 aatcgttagg gtatttgtca ggttttgaag agcctgatat tgaaaaacgg acaaaccctt
    13081 ctttgctgct tccgaaggcc aaatcaattg ttgcgatagc gctcgcgtat ccttccaaaa
    13141 tgaaagatgc tccacgaagt actaaagatg cgagaagggg aatcttttgc cgggcttcat
    13201 ggggaacgga ttatcatgtt gtgctgaaaa aaaagcttga tatgctcgaa gaatttctgc
    13261 gaagcaagca tgtcgatata aggacaaaat caatggtgga tacaggagaa ttgtctgatc
    13321 gtgctgtagc ggaacgtgcg ggcattggtt ttagtgcaaa aaactgtatg attatcacgc
    13381 cagagtttgg atcttatgtg tatttggctg aaatgatcac aaatgtccca tttgaaccgg
    13441 atgagaaaat tgaagatcag tgcggaactt gcaataaatg tgtggattcg tgtccaacgg
    13501 gtgcgctggt gaatccagga caactgaatt ctcagcggtg tatttcattt ttaacgcaga
    13561 caaaaggatt tttacctgat gagtttcgtt cgaaaatagg aaatcgattg tacgggtgtg
    13621 atacgtgcca aatcgtctgc ccgatcaata aaggaaaaga ctttcatctg catcctgaaa
    13681 tggagccgga ccctgaaatt gcgaagccgc tgttaaagcc gcttctgacg atcagcaatc
    13741 gtgagtttaa ggaaaaatac ggtcatgttt caggttcatg gcgggggaaa aagcccattc
    13801 agcggaatgc cattttggca ctcgctcatt ttaaagatac atctgcttta ccagtgttaa
    13861 ttgagttgat gcacaaggac ccaagaccgg tcattcgggg aactgctgct tgggcaattg
    13921 gcaaaattgg cgacgatcag cagcttccag agctggaaaa agcccttgaa cgggaaagtg
    13981 atgaagaagc aaaagaggag attgtgaaag ggattgagct cctgcagaca cctttaaata
    14041 ctaaataaca tccctgtgaa catagaatga accaaacaga gattttaaaa aatgtttggt
    14101 ggtgtctgtg tgaaacaatt attagagaaa actttagaag acaggctggc gtatttaatc
    14161 aatgaccgtg caatcaagca gccgcagctt atgtctgatg tggaagcagt agagcggaaa
    14221 aaagagcttt ttgctagaag acaggttgag attgtgaagg cgaaagcaaa aacaaaactt
    14281 ctcgattcag ccatacaaga tgatggagct caacatgtgc agtaccttgc tcatctcact
    14341 tatgtatgca aggatgtaga cgattctttc tatttagagg aacaggtgga aaaaagagaa
    14401 gcgttccttt ataacgacat gcttgtcaaa gatcggatga tgctagaaga gcgacaaagg
    14461 gaagagctta tggatgagcg ctttcagacc gaagaacaat tcggcagagc ttttcactat
    14521 gaccggcggg cagccgtgca gtatgcggag acatactgga ataagcggaa tccagcctat
    14581 aaaaactttg aagataactg tacaaatttt atttcacaat gtttgaaagc agggaatgcg
    14641 ccaacgagag gatatccgaa ccgcgggtct ggctggtggg tgcgtccgca tacgtggagt
    14701 tatagctgga cggtggctca ttcgatgaaa aattatttag cgaattcgaa agcgggtttg
    14761 agagcaaaga aactcaaaga agcgcacgag cttcaaattg gtgatgtcat ttgctacgat
    14821 tttgaaggtg atggaaggta taatcataca accattgttg ttgatcatga caaaggcgga
    14881 atgcctcttg tgaatgcaca gacgtatgac tgccgcatgc gttattggtc atacgaggat
    14941 tcgaccgcct atacacctgc tattcgttat atgttttttc acattttgga cgatgccgcg
    15001 aaggatagtt agtggtataa tgttgagcgg aaaagaaaat tagaggtgaa cttttttggg
    15061 acttcatgtc gttttatatc aaccagagat tccagctaat actggaaata ttgcgcgtac
    15121 atgtgcagca acaaatacaa cccttcatct gattcgtccg cttggttttt cgacagatga
    15181 caaaatgctg aagcgtgcag gactcgatta ttggaaatat gccaatgtgg tctatcatga
    15241 ttcacttgat gaattgtttg aggctcatcc gaaggggcaa tttttctata tcacaaaatt
    15301 tggccaaaag ccgcatacga catttgatta ctctcagctg gatgaagact atttcttcgt
    15361 ctttgggaga gaaacaagtg gattgccaaa agatttgatt gaacagaata tggaccgttg
    15421 tcttcgtcta ccgatgacag agcatgttcg ttccctaaat ctgtcgaata cggcagccat
    15481 tcttgtatat gaggcacttc gccagcagca atatcgcgat ctcatataag atcatgaaaa
    15541 aagccgagat tctgatctcg gctttttata tgagatcaga aacagaagag taaaaaatat
    15601 gacgtaatca tacttttttt gacatgttaa atgaaaagga tgttccgcaa atggaacatc
    15661 ctttttttca tttaccaggc ttgccttcgt agccagcagt gaaaatggat actaaaaacg
    15721 taatgatgac gcccatcata atgaccgttc tcatataagc tcccccttat ccctttgttc
    15781 cgttcgctgc ctgtttcata tgatgcgaag ttcaccttga aaagcaggag aagaaaatca
    15841 tttttctcct atttttcctt tattatgaag ggtcttgcgg atggttgtca attcagtttg
    15901 ccaattcgtc attttgaaga acgaaagcat gtaataggac gcctccgcat agattgtaaa
    15961 acagtatctg atttctagct tcaatcttga aagaggaggt tcatatggat attttaaaga
    16021 aaatcgaaca gcacagagaa gaagagcagc gtctcaaatg ggaaggcaca ttcagcgatt
    16081 atttagacat tattaaggaa aatccacttg tcgctcaatc tgctcattct cgcgtttatc
    16141 atatgattaa agacagcggg attgaagagg agaatggggt cagaacctac aaattttttg
    16201 atcaggagct gtttgggtta gaggaatcac tcgaaagatt agtagaggaa tattttcacc
    16261 ctgctgcaaa gcggctagat gtcaggaagc gtattttatt actgatggga ccagtaagcg
    16321 gggggaaatc gacgcttgtc actagattga aaagaggtct tgaagaatat tcactgacag
    16381 atcatggcgc agtttatgcg atcaaaggct gccctatgca cgaagatccg cttcatctca
    16441 ttccgcaaaa tctgcgggag gatttctata gagaatatgg gattcgtgtg caggggaatt
    16501 tgtcgcctct gaacatgatg agactggaag aggaatatgg cggcagaatt gaggatgtaa
    16561 gggtcgagcg gatctttttc tctgaagata aacggaccgg cattggtacc tttagtccgt
    16621 ctgatccgaa atctcaggac attgccgatt taacaggaag catcgatttt tcaactattg
    16681 ctgaatttgg atcagagtca gatccccgtg cgtaccgctt tgatggagaa ctcaataagg
    16741 caaaccgagg gatgatggag tttcaggaga tgttaaagtg tgatgagaaa tttctctggc
    16801 acctcctgtc attaacgcag gaaggaaatt ttaaggcagg aagattcgcc ttgattagtg
    16861 cagatgaatt gatcgtcgcc catacgaatg aaaccgagta ccggtcgttt atttcaaata
    16921 aaaagaacga ggctttgcat tcaagaatta ttgtgatgcc aattccttat aacttaaagg
    16981 tcacagaaga agaacgcatt tattataaaa tgatttcaga aagtgatgtc tcagatgtgc
    17041 atattgcccc tcatacgctg aaggtagcag cgatgttctc cattttgacg agattgaaag
    17101 agccgaagcg ttctgatatt gatttggtga aaaaaatgcg tctgtatgac ggagaaagtg
    17161 tcgaaggctt ccagtcagtc gacattgatg agatgaaaaa ggaatttcat gacgaaggga
    17221 tgagcggaat tgatccgcgg tatgtgatca atcgaatttc atccacgatc attcgaaaga
    17281 atatggaatc gatcaatgca ctggatgtcc ttcgctcctt aaaagaaggg ctcgatcagc
    17341 atccgtctat ctccagcgag gaccgggagc gttatttgaa tttcatttca gtcgcgagaa
    17401 aagaatatga tgatattgcg aagaaggaag tgcaaaaggc atttgtgtac tcctatgagg
    17461 agtctgcgaa aacgctgatg gataattact tagataatgt cgaggcatac tgcaataaaa
    17521 acaagctgcg tgatccgtta acgggtgaag aaatgaatcc tgatgaaaaa ctcatgcgtt
    17581 caattgagga gcagatcggt atttctgaaa acgccaaaaa ggcatttaga gaagaaattc
    17641 tgattcgtat ttcggcttat gcgagaaagg gaaaacgctt tgattataat tcacatgaga
    17701 gattgcggga ggccattcag aagaagttat ttgctgatct aaaagatgtg gtgaaaatca
    17761 cgacatcgac gaagacaccg gatgaacagc agctgaagaa ggttaatgaa gtagtggcta
    17821 gattgattga tgagcatggc tataattcaa caagtgcaaa tgaactttta aaatatgtag
    17881 gcagtcttct gaatcgttaa taaatgaagg aggcattatt ggcgcatcag caccggtaat
    17941 gtctttttta gaaatgatcg tcaacttgga tgacgagcag catacgataa aggaattgat
    18001 ggttagaaga attgtgcaaa taggtgagga gggggatgga tgtcccggca agaaaaaagt
    18061 cagtttattg tgtcacagga agactggtcc ctccatcgaa aaggctatga cgaccagcag
    18121 cgtcatcaga aaaaagtcaa agaggcgatt aaaaacaatt tgccggacct tgtcacagaa
    18181 gaaagcatta tcatgtcgaa tggaaaagat gttgtcaaaa ttccgatccg ttcattagat
    18241 gaatataaaa ttcggtataa ctacgacaaa aataagcatg tgggtcaagg cgatggagac
    18301 agtgaggttg gcgatgttgt tgcgcgtgac ggctcagaca gtaagcaggg ccaaggaaag
    18361 gggcagggcg ctggagatca agctggtgag gattattatg aagcagaagt ctcattaatg
    18421 gatctcgagg aagcactgtt tcgtgaactg gagctgccaa acctcaagca aaaggagctt
    18481 gacgacatca ttgtcgaaca aattgagttt aacgatattc gtaaaaccgg gttaacagga
    18541 aatatccaca aaaaacgaac aatgctgtcg gcatttaaac gaaatgcgat gacaggcagt
    18601 ccttcctttt atcccatcta cccggaggat atcaagtata aaacgtggaa tgaagtgacc
    18661 aaaccagagt cgaaagccgt cgttttagcg atgatggata cgagcggaag tatgggactt
    18721 tgggaaaaat atatggcgag aagttttttc ttttggatga cacgtttctt acggacaaag
    18781 tatgagacgg tcgatattga atttattgcc caccatacag aggcgaaggt ggtagacgaa
    18841 gaacatttct tctcacgggg tgagagcggg gggaccattt gctcgtctgt ctatcgaaag
    18901 gcactagagc tcatagacga acgatacccg ccgtcgcgat ataatattta tccttttcat
    18961 ttttctgatg gggacaattt gacctcagac aacgcccgat gtgtgaaact tgtttctgag
    19021 atcatgaaaa aagccaattt attctgttac ggtgaagtga atcaatacaa ccggcattct
    19081 acgttaatgt cagcatataa gcatattcag gatgagaaat ttaagcatta tattttgaag
    19141 caaaaatcag acgtttttct cgcactaaaa aaattttttc agcaggaaga agttcattca
    19201 taacgagcac atttgaaaaa acctttcagc ataagggctg aaaggttttt ttgtgtggag
    19261 aaggaaagga tcaccagaaa aaaagtaaaa ctttctcttt gacatttcaa ttttcattta
    19321 ttaatattta atcttgttaa atataagttt ttcaaaaaag atgccgatcg tcttttcttc
    19381 tttttctgct ctttgctcat aagtgaacaa taagtataaa tgggctgcac accatgatag
    19441 gggcgggagt agatgaaggg aaaaggacag attgttgagc ttgtttcata ttctgtcaga
    19501 tgatgggcat tctaagtttg ctaaagcaga tgacactata tttttataca tgaaaggaga
    19561 aacaaaacat gaacagaggg cgtttattgc taacgaacat tattggcctt attgtgattc
    19621 ttgccattat tgctggaggt gcttattact actacgaaag cacaaatttt gttaaaacag
    19681 acgaggcaaa agtgacaggt gacatgtatc aaattacagc accagcagct ggacaaatca
    19741 aaggctggga tatcaacgaa ggtgacgaag tggaaaaaga cagcacagtt gcaaaagttg
    19801 aaggacaaac aaaaacaaac attaaagcag tggctgatgg cacattagtc aaaaaagaag
    19861 tacaaaacaa tcaacaagtg cagcctggta cagttcttgg tgaaacaatt gatttaagca
    19921 agctttacat cacagcaaat attaaagaaa cagatattaa aaacattgaa aaaggcgaca
    19981 aagtcgacat cgttgtagat ggcgatcctg atacaacatt tgaaggaaac attgaacaaa
    20041 ttggttatgc gacaaactca acattcaata tgctgccagc aacaaattca agtggcaact
    20101 atacaaaagt aacgcaaaaa gtagcagtga aaatttcaat taaaaaccca tcagacaaag
    20161 tacttccagg tatgaatgct tctgtcaaaa tttcatctta atgatgattg atatcaaaaa
    20221 atgaaaggag gttgtctgag atggcaaatc aacctgcagc gacaaaacag ggaacaggct
    20281 ccttgtcttt actgatcatt ttaatggccg gtttgttcgt agcgatttta aaccaaacgc
    20341 ttttgaacgt agccatgccc catttaatga ctgaatttaa tgtaagtgca acgacgattc
    20401 agtggcttac cacaggctac atgcttgtca acggtgtgct gattccgtta tctgcgttct
    20461 taatcacacg ttttggacag cgcagcttat tcctagtggc tatgatctcg tttacgctag
    20521 gtacatttat ttgcggtatt gcgccaaact tttcaacaat gctcatcggc cgtttgattc
    20581 aggctgtcgg cggtggtatc ttacagccgc ttgtcatgac aacaatcctt tttattttcc
    20641 ctccggagaa cagagggaaa ggaatgggga tttttggtct tgcgatgatg tttgctcctg
    20701 cagtaggacc aacattatct ggttacatta ttgaacatta ttcttggcgt attatgtttt
    20761 atggacttgt gccaatcggt gcgattgtca ttatcgcggc tttctttatg tttaaaaata
    20821 ttgtagagcc taaaaaaatc aagctggaca gtcttggtgc gattctttca atcgtcggtt
    20881 ttgcttccct tctatacgga gtgagt
//
