LOCUS       NZ_CP027059            23632 bp    DNA     circular CON 16-JUN-2024
DEFINITION  Paenibacillus konkukensis strain SK3146 chromosome.
ACCESSION   NZ_CP027059
VERSION     NZ_CP027059.1
KEYWORDS    RefSeq.
SOURCE      Paenibacillus konkukensis
  ORGANISM  Paenibacillus konkukensis
            Bacteria; Bacillota; Bacilli; Bacillales; Paenibacillaceae;
            Paenibacillus.
REFERENCE   1  (bases 1 to 7969064)
  AUTHORS   Jung,H.I., Park,S., Niu,K.M., Lee,S.W., Kothari,D., Yi,K.J. and
            Kim,S.K.
  TITLE     Complete genome sequence of Paenibacillus konkukensis sp. nov.
            SK3146 as a potential probiotic strain
  JOURNAL   J Anim Sci Technol 63 (3), 666-670 (2021)
   PUBMED   34189514
REFERENCE   2  (bases 1 to 7969064)
  AUTHORS   Kim,S.-K., Jung,H.-I. and Lee,S.-W.
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2018) Department of Animal Science and Technology,
            Konkuk University, Neungdong-Ro, Seoul 140701, South Korea
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: 26-MAY-2016
            Assembly Method                   :: other v. HGAP
            Expected Final Version            :: yes
            Genome Coverage                   :: 7968964.0x
            Sequencing Technology             :: PacBio
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_023523925.1-RS_2024_06_15
            Annotation Date                   :: 06/15/2024 05:36:52
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 7,013
            CDSs (total)                      :: 6,868
            Genes (coding)                    :: 6,761
            CDSs (with protein)               :: 6,761
            Genes (RNA)                       :: 145
            rRNAs                             :: 13, 12, 12 (5S, 16S, 23S)
            complete rRNAs                    :: 13, 12, 12 (5S, 16S, 23S)
            tRNAs                             :: 104
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 107
            CDSs (without protein)            :: 107
            Pseudo Genes (ambiguous residues) :: 0 of 107
            Pseudo Genes (frameshifted)       :: 45 of 107
            Pseudo Genes (incomplete)         :: 72 of 107
            Pseudo Genes (internal stop)      :: 13 of 107
            Pseudo Genes (multiple problems)  :: 20 of 107
            CRISPR Arrays                     :: 10
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 10:26:11
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 5024523
            Orig. end                         :: 5048155
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP027059.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            Bacteria and source DNA available from Soo-ki Kim.
            Genome not circularized.
            This genome has a base modification file available.
FEATURES             Location/Qualifiers
     region          1..23632
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="azole-containing-RiPP"
                     /region_number="8"
                     /rules="((YcaO or TIGR03604) and (((thio_amide and (PF06968
                     or PF04055 or PF07366)) or Lant_dehydr_C or Lant_dehydr_N
                     or (PF06968 or PF04055 or PF07366)) or (goadsporin_like or
                     PF00881 or TIGR03605)) or TIGR03882 or TIGR03603 or
                     thiostrepton or TIGR03602)"
                     /tool="antismash"
     cand_cluster    1..23632
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="((YcaO or TIGR03604) and (((thio_amide
                     and (PF06968 or PF04055 or PF07366)) or Lant_dehydr_C or
                     Lant_dehydr_N or (PF06968 or PF04055 or PF07366)) or
                     (goadsporin_like or PF00881 or TIGR03605)) or TIGR03882 or
                     TIGR03603 or thiostrepton or TIGR03602)"
                     /kind="single"
                     /product="azole-containing-RiPP"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..23632
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:13632](+)"
                     /cutoff="10000"
                     /detection_rule="((YcaO or TIGR03604) and (((thio_amide and
                     (PF06968 or PF04055 or PF07366)) or Lant_dehydr_C or
                     Lant_dehydr_N or (PF06968 or PF04055 or PF07366)) or
                     (goadsporin_like or PF00881 or TIGR03605)) or TIGR03882 or
                     TIGR03603 or thiostrepton or TIGR03602)"
                     /neighbourhood="10000"
                     /product="azole-containing-RiPP"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..13632
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="((YcaO or TIGR03604) and (((thio_amide and
                     (PF06968 or PF04055 or PF07366)) or Lant_dehydr_C or
                     Lant_dehydr_N or (PF06968 or PF04055 or PF07366)) or
                     (goadsporin_like or PF00881 or TIGR03605)) or TIGR03882 or
                     TIGR03603 or thiostrepton or TIGR03602)"
                     /neighbourhood="10000"
                     /product="azole-containing-RiPP"
                     /protocluster_number="1"
     gene            complement(58..846)
                     /locus_tag="SK3146_RS22035"
                     /old_locus_tag="SK3146_04405"
     CDS             complement(58..846)
                     /GO_function="GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007127193.1"
                     /locus_tag="SK3146_RS22035"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SK3146_04405"
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="WP_249860793.1"
                     /transl_table=11
                     /translation="MKDSVTFWGTGDSMGVPRVYCSCDICDEARGAGSNRRYRSSIMLH
                     AGDSELLVDCGPDWRGQMERAGKRFVERVLITHAHFDHIGGLPEWADACRWLKRKGRLY
                     APLEVLQTIQKQFPWLQNQLQFHDCAGGLQWEHWRIRPWRVCHGKNGYSYAYRFERTAG
                     PSYAFVYCPDSIRLSDEEKAPLFGLQLLILGTNFYKEEAAPATRSVYDMVEALELISEI
                     SPGRVIFTHMSHGVDLARSYPLPSFVSLAQTGLTIELEPS"
     gene            989..1609
                     /locus_tag="SK3146_RS22040"
                     /old_locus_tag="SK3146_04406"
     CDS             989..1609
                     /EC_number="3.6.-.-"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017550107.1"
                     /locus_tag="SK3146_RS22040"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SK3146_04406"
                     /product="NUDIX hydrolase"
                     /protein_id="WP_249860794.1"
                     /transl_table=11
                     /translation="MAEDTRGIDWAKRIQAIAQAGLAYSRDAFDLERFEELRSISVEMM
                     AAYSGLDIRQVNHLFAGESGYATPKVDIRGVVIRDGKILLVQEKNDGGWSLPGGWADIG
                     LSPREIVVKEVKEESGYDVAPVRLLAVLDRNKHPHPPHAYDIYKIFIQCELTGGQARAS
                     IETSDVGFFAPDDLPQLSTDRITESQIELLFRQVREPGEAVFD"
     gene            1631..3454
                     /locus_tag="SK3146_RS22045"
                     /old_locus_tag="SK3146_04407"
     CDS             1631..3454
                     /EC_number="2.7.13.3"
                     /GO_function="GO:0000155 - phosphorelay sensor kinase
                     activity [Evidence IEA]"
                     /GO_function="GO:0004673 - protein histidine kinase
                     activity [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_process="GO:0007165 - signal transduction [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010492691.1"
                     /locus_tag="SK3146_RS22045"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SK3146_04407"
                     /product="sensor histidine kinase"
                     /protein_id="WP_249860795.1"
                     /transl_table=11
                     /translation="MASRLLARFHHFLLGTSLQNKLIIFFLPLAIIPLSILGTFSYYKS
                     SQVVQTQVCQTILESLSQVNYSLNYFVKDIEQLTMYIYSNREIQDVLSKSSDRPLAEKH
                     QDEKRIQDLLETFLGFKSWNIAIYLLGENGDRYFTGNLLPSQYDDYNVNWGLFRKMSLA
                     GGNVVWDTHYSMKKTEDFGIVLSSGRLLKKIETSQPLGYMIVDIMENALADKYNKAHLQ
                     PGGQMLLLDRGGYVISSTPSKHIVGTKLNEPYLDQVLAGSKGFFELQGVSGAPPAMVVY
                     DTSEMTGFKLVSVVPIEMLTKESSSIRNLTLYVIICFGIVTFWLAYVLSVTITKPLRKL
                     KSLMYLVENGNMDVAFPSKYRDEVGQLGLSFNKMLLRIKQLIDEVYKKQLMVQEAEIKA
                     IQAQFNPHFLYNALDSINWMARIHKLPDISQTVVSLGELLRFSIRKGQPFIQVKEDMQQ
                     IRNFLVIQKMRYGDKLEAELEIDEEIEPLYTLKLLIQPLVENAVTHGLEVKPGKGHLSI
                     RGRRVGDKVRFEVSDDGAGMPRERVERILSGKYEAPDGRSTGIGLENLRKRLELYFGGR
                     YRLDIRSEEGQGTTVTVEIPVMRTAGEDQHV"
     gene            3447..5051
                     /locus_tag="SK3146_RS22050"
                     /old_locus_tag="SK3146_04408"
     CDS             3447..5051
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_function="GO:0043565 - sequence-specific DNA binding
                     [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1016: LuxR family
                     DNA-binding response regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: protein motif:HMM:NF012301.4"
                     /locus_tag="SK3146_RS22050"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SK3146_04408"
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="WP_249860796.1"
                     /transl_table=11
                     /translation="MYKVFLVEDEWLVLQGLKLTIPWEELNCEIIGEASDGRTGAELIL
                     TAKPDIVLTDIRMPAMDGIQLAEQVAAGLPGIKIVFLTGFDDFAYAQKAVKLGAADFVL
                     KPTNADELIQVIGRITSQLDTERSRRSFQERLEHRAKLEHPLIMEKMLYELMQDYAGPT
                     LKELFLEYGEWSEAGAEGDGFPPYRLLLIQLDGLCRESAERERQLEQVREQAQELSALP
                     VVRMSENRYALIANRRTGREALMEAAAALLRRLPVLTRSYVIGVSALFTAGIESLPAAY
                     QQAMRALYQTVFLGRETWIWYEDIEREQADEPGSEDAVQEWIDLVKWGHAASIEAHTAA
                     WYSRLLHRYPDGLEARRRFFEFIVALYSALLRDHELREIVLGSDFLLAFAERLEHTLER
                     SLELLCAMLAEWNGLLAEQGETRKKSGFEEIEAFIQSHYAEDITLQGIAERYHMSESYF
                     SRLFKKQVGTSFLEYVTMIRVRQAKELLANPRLKIYEVSLQAGYQDSRYFSQIFRKYTG
                     ETPTEFRKRLGIEPLPL"
     gene            complement(5166..5510)
                     /locus_tag="SK3146_RS22055"
                     /old_locus_tag="SK3146_04409"
     CDS             complement(5166..5510)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1167:
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003338802.1"
                     /locus_tag="SK3146_RS22055"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SK3146_04409"
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="WP_249860797.1"
                     /transl_table=11
                     /translation="MEPGCEQPLALTKGTLGDICPIVKAIEVIGTKWTFLIIRDLLIEG
                     TMRFSDLLKCLDGISPKTLSLRLRELEEHGLVTRTVYPEVPPRVEYRLTDKGKKLEQIF
                     IELKRFGLTL"
     misc_feature    5662..5675
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 18.17"
                     /tool="antismash"
     gene            5718..6737
                     /locus_tag="SK3146_RS22060"
                     /old_locus_tag="SK3146_04410"
     CDS             5718..6737
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1217: NADH:flavin oxidoreductase/NADH oxidase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016740841.1"
                     /locus_tag="SK3146_RS22060"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SK3146_04410"
                     /product="NADH:flavin oxidoreductase/NADH oxidase"
                     /protein_id="WP_249860798.1"
                     /transl_table=11
                     /translation="MPSLSSSFSLKGLQLKNRVVMPPMCQYSVEAKDGIPTDWHFVHYV
                     SRAVGGTGLIIMEMTDVEPDGRITDYDLGLWSDDQIPAFRRIIQEVQKYGAKIGIQIAH
                     AGRKAEDAEIPVGPSNIPVSPEFKTPRALTTDEVKAMVVKFKEAAVRAVEAGVDTIELH
                     GAHGYLIHQFHSPAINNRTDEYGQDLARFGVEIIQAVKSVMPENMPLIMRISAVEYMDE
                     GYDLGHSIEISRRYKEAGVDMFHVSSGGEGPSGSRKPGNYPGYQVPMARAIKLALSVPV
                     IAVGILEDAKLAEATVANEDADLVGVARGMLRDPYWAAHAIRETTGQVAAPRQYERAY"
     misc_feature    complement(5719..5735)
                     /note="TFBS match to GnfM, Regulator of nitrogen-fixation
                     genes, confidence: weak, score: 20.81"
                     /tool="antismash"
     misc_feature    complement(5761..5770)
                     /note="TFBS match to ToxT, Regulator of MSHA biosynthesis,
                     confidence: medium, score: 16.04"
                     /tool="antismash"
     gene            complement(7417..7725)
                     /locus_tag="SK3146_RS22065"
     CDS             complement(7417..7725)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="SK3146_RS22065"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_249860799.1"
                     /transl_table=11
                     /translation="MMTVMAIVAVMAGVTVMAIVTIVAGMTVMAIVTIVAGMTVVAVMA
                     GITVMAIVTIMAVVPCMPGSCILLILAVPRVDRSPFDIGNVQLLQILFEISHLYHPP"
     aSDomain        7932..8225
                     /aSDomain="Heterocycloanthracin_C_RRE"
                     /aSTool="RREfinder"
                     /database="RREFam.hmm"
                     /description="RRE-containing C protein in a
                     heterocycloanthracin LAP cluster"
                     /detection="hmmscan"
                     /domain_id="rrefinder_SK3146_RS22070_Heterocycloanthracin_C
                     _RRE.1"
                     /evalue="1.10E-42"
                     /identifier="RREFam011.1"
                     /label="SK3146_RS22070"
                     /locus_tag="SK3146_RS22070"
                     /protein_end="98"
                     /protein_start="0"
                     /score="134.9"
                     /tool="antismash"
                     /translation="MVQLNPSMRLKVNRDTFVMPEPGGSVYVRNNARSFRMEGEAADQW
                     LEKLLPVFNGEYTLGELTDGLAEPYIIQVYSIAAMLHENGFVRDVSGDKPHRL"
     gene            7932..10004
                     /locus_tag="SK3146_RS22070"
                     /old_locus_tag="SK3146_04412"
     CDS             7932..10004
                     /GO_component="GO:0005575 - cellular_component [Evidence
                     IEA]"
                     /GO_function="GO:0003674 - molecular_function [Evidence
                     IEA]"
                     /GO_process="GO:0030152 - bacteriocin biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) TIGR03693"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Heterocycloanthracin_C_RRE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Thiopeptide_F_RRE"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009676365.1"
                     /locus_tag="SK3146_RS22070"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SK3146_04412"
                     /product="putative thiazole-containing bacteriocin
                     maturation protein"
                     /protein_id="WP_249860800.1"
                     /sec_met_domain="TIGR03693 (E-value: 1.1e-178, bitscore:
                     594.0, seeds: 2, tool: rule-based-clusters)"
                     /sec_met_domain="Heterocycloanthracin_C_RRE (E-value:
                     2.6e-40, bitscore: 134.9, seeds: 5, tool:
                     rule-based-clusters)"
                     /sec_met_domain="Thiopeptide_F_RRE (E-value: 3.4e-09,
                     bitscore: 35.2, seeds: 20, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MVQLNPSMRLKVNRDTFVMPEPGGSVYVRNNARSFRMEGEAADQW
                     LEKLLPVFNGEYTLGELTDGLAEPYIIQVYSIAAMLHENGFVRDVSGDKPHRLPEAIRE
                     RYGSQIEFIEQFTDSGGFRFQKYRQTRVLVIGNGEMLAAQTAALLYSGLPRFRVLIGDS
                     KTTERRRLEELAAHARRSDPEVDVELTEPGGGELPSWKEAVQGFEAVVYAARTDDPEEL
                     RRVHAACREEGKLFVPAVCLPQIGWAGPLVHPAADACWESAWLRLHRSVTERDPRQHGY
                     SSTAGALLANIAAFELFKHVTEAGPRRSSGSGQCYLLDLETLEGAWHPFLPHPLATGTL
                     GSMLMKDWEQWLEEKSEPQPGVWLACFGRITSKAFGVLDSWDEEELVQLPLAVCRAQAA
                     DPLSDGPSELLPSVLCAGLTHEEARREAGLAGVEAYAARWTEVSGAGRFAGKEPDITAI
                     AAETAELIGVGAGETAAEAISRGLYKRLSAELGRRLDASPVAIAPAQPDAVEDARCRFY
                     FQAISLMGGAPQLGIGEELYGFPVVWVRSGDRWYGSTGLNRTLALREALKRAALARQCE
                     ENCSAGETVSRNQPQEPPIGEQAQHPAQEGGRLQGPAPVQVRSDRAVHIKPDEPLRLAV
                     PPAEDGDTAAILHSALHVLNRQGLRLEVIDMAVEPFMREGLAGVVGILLRGEEMR"
     aSDomain        7953..8198
                     /aSDomain="Thiopeptide_F_RRE"
                     /aSTool="RREfinder"
                     /database="RREFam.hmm"
                     /description="RRE-containing F protein in a thiopeptide
                     cluster"
                     /detection="hmmscan"
                     /domain_id="rrefinder_SK3146_RS22070_Thiopeptide_F_RRE.1"
                     /evalue="1.40E-11"
                     /identifier="RREFam004.1"
                     /label="SK3146_RS22070"
                     /locus_tag="SK3146_RS22070"
                     /protein_end="89"
                     /protein_start="7"
                     /score="35.2"
                     /tool="antismash"
                     /translation="MRLKVNRDTFVMPEPGGSVYVRNNARSFRMEGEAADQWLEKLLPV
                     FNGEYTLGELTDGLAEPYIIQVYSIAAMLHENGFVRD"
     gene            10001..11941
                     /locus_tag="SK3146_RS22075"
                     /old_locus_tag="SK3146_04413"
     CDS             10001..11941
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     azole-containing-RiPP: TIGR03604"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     azole-containing-RiPP: YcaO"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013877478.1"
                     /locus_tag="SK3146_RS22075"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SK3146_04413"
                     /product="TOMM precursor leader peptide-binding protein"
                     /protein_id="WP_249860801.1"
                     /sec_met_domain="YcaO (E-value: 5.8e-79, bitscore: 264.8,
                     seeds: 127, tool: rule-based-clusters)"
                     /sec_met_domain="TIGR03604 (E-value: 9.1e-119, bitscore:
                     395.3, seeds: 25, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSALVVIVGEGQLADLVAGDLARSFRVVRRQSISGGMAGADLALT
                     LHDGWQPGIHLRAEEELPPAGIPWLRACVLFGEGLVGPLVKPGAPGCSQCADARLHMAG
                     QDRPSMWRLRRKLAEEGGTERDAWDARGGMLQLALLTAAQSRKALERPDEADSGLMHIV
                     NMHTLAISRHRVLPDAHCPVCSRIRDDTEAAARITLQPNPKERPDSYRIRSMEELRDAL
                     AADYLDSRTGLLNAAVTDLVSPFADASVNLPLMNEDVGAAGRTHSYEASRLTAMLEGLE
                     RYSSIRPRGKRTSVYGSYQELREQALDPVKTGVHSAEQYALPGYPFRPFDPEAPLRWVW
                     GYSFLQERPILVPESLAYYGSGGGQSFVFESSNGCALGGSLEEAVLHGILEVAERDAFL
                     MTWYARLPLPRLDLSTAGDAELNLMLARLEAVADFDVRFYNATMEYGIPSVWGIAVNRK
                     RQGLRLLCGAGAHPDPVRAVKGAVHELAAMALNLGPKLAGDLERYEAMLRDSSLVARME
                     DHSLLYGLPEAQERLGFLLDDSRPARSFAAEFPAKKIYADLTDELRALLRSLGRRQLDV
                     IAVDVTAPEIARNGLFCVKVLIPGLIPMTFGHSFTRLTGLERLLTVPAELGYADRPLTP
                     DQLNEFPHPFP"
     gene            11980..13632
                     /locus_tag="SK3146_RS22080"
                     /old_locus_tag="SK3146_04414"
     CDS             11980..13632
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     azole-containing-RiPP: PF00881"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019003928.1"
                     /locus_tag="SK3146_RS22080"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SK3146_04414"
                     /product="SagB family peptide dehydrogenase"
                     /protein_id="WP_249860802.1"
                     /sec_met_domain="PF00881 (E-value: 2.3e-07, bitscore: 29.7,
                     seeds: 78, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNRLDAFMHDLHFHIDRTKPPDRVVDWEDGPLAFKLYRGLPVFPL
                     AADIPLSIAAEGANAPGRRIGLRSLGHLLWYAYGLTELSHSVQSSFSSGTDLFQMYRRF
                     APSGGALYPSELYVYLKLDTLPAGVYHYDAAHHRLVLLREGDCDAFLQRALGERFERSR
                     CCGAAFVSAMFWKNFFKYDSFAYRLQGLDAGTMIGQLLEAAERFGVATAVHFQFADRAI
                     HHLLGLSELEESVYAVVALSDAPAPCPPCLGTEPEERGGSDRSGRSERQSEDGRSAEAW
                     YRELPPVSHEHYVRSKRIKPYPLLLEMNEASMLASVSAPALEAFARPPAARRKLPGIEG
                     VVRLPAAERLAYDWAAASRRRFSPDTDFALGPVSLGQLSALLRETAASLRCRCDLDGGV
                     LQEQPRLSLYVCLHHVEGIEDGAYVYDIPEHALVAVREGDLRLWLQIGMNSDNVNLLQV
                     PLVFHVAGDRNHYTQELGYRGYRIQQMEAGMLVQRLLLAASALGLGGHPLLDYDARLCD
                     ELYRLPAEGLTSLIQVPIGPYRPCPKLAGGLHG"
     misc_feature    14067..14085
                     /note="TFBS match to DmdR1, Iron(II)-dependent repressor,
                     confidence: weak, score: 23.84"
                     /tool="antismash"
     misc_feature    complement(14095..14106)
                     /note="TFBS match to CcpA, Catabolite control protein A,
                     confidence: medium, score: 16.97"
                     /tool="antismash"
     misc_feature    complement(14220..14233)
                     /note="TFBS match to PerR, Peroxide regulator, confidence:
                     weak, score: 18.61"
                     /tool="antismash"
     gene            14250..16583
                     /locus_tag="SK3146_RS22085"
                     /old_locus_tag="SK3146_04415"
     CDS             14250..16583
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_function="GO:0043565 - sequence-specific DNA binding
                     [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1287: AraC family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: protein motif:HMM:NF037653.4"
                     /locus_tag="SK3146_RS22085"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SK3146_04415"
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="WP_249860803.1"
                     /transl_table=11
                     /translation="MLRRNGANRTRARHRLFARLLIPYLVFLMLAIMIGLIIYQKTIVL
                     IEKEATASHMNLLEQSKDILDRRLEELASIAQQLAADTRIMQFQSVTDPYKGTNTFRIM
                     DTNKSLYDYKLSNNFVFNYYVLFKNSEMVFTPGASYSFEHFFNRVANYKGMNYTSWYAL
                     MSSDFHMRKVLPAQEISMEGVPYSMLTYIQSLGYPGNPQGAIAIMVDQREIQKLFQGLD
                     ISSGGWAYIVDKEGQIISALSPGDANTLPIELGRLAGDRGVVEQRIDAKPMMVTYTKSS
                     YNGWTYVVGQPTAIALGKVRYIQKIIVTFACVFLLAGVLAAYVLAYRNSKPLRALINTI
                     MEKTDVLPQQRDAFGIIGETVNGLFQNNDKLKAEIKQQVPLLRAAYFQRLLNGQFVSSR
                     DFDALLKHVGLDLVGMSYRVAIVRLRGFDKGYSDDLLEELDRSRVLAKELLRRTMDEDG
                     FVCEIGEDQFAVLFTYKLDEREPYKAYVEARLKEARDEIGLQLKLQSVYGVGGACDSLT
                     GISRSYEQAREALNAQLWSNQEGGLWFDELPADMANYYLPQDVETRLIHLAKAGDQTEV
                     QRTLDELYRENFELRQLPIAVMKLFIFEMWGCLVKLLPQMDLDQQTAYNRMSALSGANE
                     SYESMSKSYQAIRDTFQWVCESANEHKKSQNVELIDSIIGLLQSSYMDSELCLDVVADR
                     IRISKVYLSQFFKEQTGVNFSDYLESLRMDEAKALLQTTSLTVNDISDRVGYSSSNTFC
                     RAFKRLHGVSPTAFRKLVLKKLPG"
     misc_feature    16677..16690
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 19.39"
                     /tool="antismash"
     misc_feature    16678..16691
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 19.13"
                     /tool="antismash"
     gene            16842..17783
                     /locus_tag="SK3146_RS22090"
                     /old_locus_tag="SK3146_04416"
     CDS             16842..17783
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1067: putative ABC
                     transporter permease protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006211928.1"
                     /locus_tag="SK3146_RS22090"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SK3146_04416"
                     /product="ABC transporter permease subunit"
                     /protein_id="WP_249860804.1"
                     /transl_table=11
                     /translation="MKASTNKKRQPFSVWKQMKRSWQLYVLLTLPVLYVLVFKYYPMYG
                     AQIAFKDYIASKGITGSEWVGLKHFIRFFNSYEFGKLMKNTLIISVYSLLAGIPFPILL
                     ALSLNYVKNRLFKKTVQMITYAPHFISVVVLVGIILELLDPRKGIVNLLLGKLGVEPIN
                     FMAVPEYFSSIYVWSGIWQNVGFSCIVYLAALAGVDPAQHEAAVIDGANKFQRMRHIDL
                     PSIIPVMMILLILNTGNILDLGFEKVLLMQNSLNARTSEVIDTFVYKVGLASQAMNYSY
                     STAINLFKSVVGLILLLTVNQIARKTKQESLW"
     gene            17808..18704
                     /locus_tag="SK3146_RS22095"
                     /old_locus_tag="SK3146_04417"
     CDS             17808..18704
                     /GO_process="GO:0008643 - carbohydrate transport [Evidence
                     IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1069: putative ABC
                     transporter permease protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009593621.1"
                     /locus_tag="SK3146_RS22095"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SK3146_04417"
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="WP_249860805.1"
                     /transl_table=11
                     /translation="MEQTNIKEASADRWFNAVNYIVLMLFLITVLYPLLFIVSASFSSP
                     GAVMSGKVWLWPVEPGLQGYAAVFKHKLIWSSFRNSVFYTVAGTLINVALTVMAAYPLA
                     RKDLYGKNAVMLLLVFTTIFSGGLIPSYILVKDLGMLNTVWAMILPSAMSVFNVIIART
                     YFKTTIPEELLEAAQLDGCNDFKFVWKIVIPLSGPIIAVIMLYSAVGYWNQYFNAMIYL
                     KQPALYPLQLVLREVLIQNEVDTSMLASLEDQAKMEGMRSLLKYSLIVVSSLPLLAVYP
                     FVQKHFVKGVMIGSLKG"
     gene            18755..20428
                     /locus_tag="SK3146_RS22100"
                     /old_locus_tag="SK3146_04418"
     CDS             18755..20428
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1143: sugar-binding lipoprotein"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018759862.1"
                     /locus_tag="SK3146_RS22100"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SK3146_04418"
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="WP_249860806.1"
                     /transl_table=11
                     /translation="MRKWMTAGLVLTLGTAAVLSGCADKGEQKEGADSAQQAKVNPAGQ
                     FPITPEKTTLKVLVKGSPFVEDFATNEFTKFLEEKTNIHIEWDVAPEKSATEKLNLVLG
                     SGDLPDVIMGFGVSPTQQLIYGSQGDFLDLSPYIEKYGVETKRMFEQVPGVKDAITAPG
                     GKIYALPMVNECFHCSASQKLWIYKPWLDKLGLSVPKTTDELYEVLKAFKTKDPNGNGK
                     ADEIPLAGAAVGPNVNVDSFIMNAFILDSSAYGVGTNNYTRLFVNDGKVDVPYNKPEWK
                     EGLAYMHKLYAEGLIAPQTFTQDRDQARQMGENPDVNILGAEMAQHNGVFTTFSGPSGR
                     WLEVTSVPPLKGPKGVQVTPINNSIGQGRYIITKASKNPDAAFRLADMLYTEEMTLRET
                     IGRPDVEWKYADKGEIGINGKQAIWKKTGAVLPTVQNVTWSQTAPTLRTNDFRLGQVAD
                     PNNPQETILYNETMQNYQPYKQDMKTFLPQLFFTNDQAMELADLEKTITDHVQEMIARF
                     VIGDASLDKDWDAYLKNLDNMNLKRYLEIYQTAYDAKMKK"
     gene            20779..21546
                     /locus_tag="SK3146_RS22105"
                     /old_locus_tag="SK3146_04419"
     CDS             20779..21546
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003347997.1"
                     /locus_tag="SK3146_RS22105"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SK3146_04419"
                     /product="threonine/serine exporter family protein"
                     /protein_id="WP_249860807.1"
                     /transl_table=11
                     /translation="MEHTLKSEADIAKVCLLAGKIMLQSGGETYRVEDTMIRIAASFGI
                     ENSHSYVTPTGIFFSIDGTEPATQLIRIMERSTDLRKVALVNDISRKISSGAMTTAEAY
                     QALKEIDRANLAYPLWLQIAAAALASGCFLIMFQGTRADFIPAMVTGGLGFWAYLLVQR
                     WVVIKFFAEFAAALLLGSLSFLLVHTGFGRDLDKIIIGSVMPLVPGLLITNAVRDLMAG
                     HLVSGLSKGAEAFLTAFAIGSGIGFVLSFYAAG"
     gene            21579..22007
                     /locus_tag="SK3146_RS22110"
                     /old_locus_tag="SK3146_04420"
     CDS             21579..22007
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015592265.1"
                     /locus_tag="SK3146_RS22110"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SK3146_04420"
                     /product="threonine/serine exporter family protein"
                     /protein_id="WP_249860808.1"
                     /transl_table=11
                     /translation="MVIEQLVTSFISSAAFGVLFNVPKKNLPQCGFVGMLGWLLYISCM
                     KAWDNPIVSSLIAAFFVTVLSQFLAKVYKTPIIIFSVSGIIPLVPGGLAYDAMRNVVEN
                     QYDVAVQLAAKAFMISGSIAIGLVFSEVINQVIRRSRL"
     gene            22207..23271
                     /locus_tag="SK3146_RS22115"
                     /old_locus_tag="SK3146_04421"
     CDS             22207..23271
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF024808.4"
                     /locus_tag="SK3146_RS22115"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SK3146_04421"
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="WP_249860809.1"
                     /transl_table=11
                     /translation="MRKAVTTVLASLLLVTSLVGCGAKETPSAKPAEGGQQPAAQQSAP
                     KSGGKLTLYSPNAAEVNNPIIKEFQDRTGIEVQLISGGTGDLLKRVQAEAANPLGDVFW
                     AGGADSLEAYKKYFEPYKTKEYDNLAPEYVDKNNVWTPFAALPMIIMYNKELVKEGEEP
                     KGWNDLLDPKWKGKIAFADPAKSGSSYTQLITMLTANGKDNGWGFVKKFVQNLDGKVLS
                     GSGLVYKGVADKEFALGVTLEEAALRYVEGGAKVGIIYPSEGTSAVPDGCAIIKGAKNM
                     DQAKQFIDFLVSKDVQSLIQKEFKRRSVRKDAEVVQGIAQAKDIKLVDYDFDWAASKKD
                     ENIKRFGKIVTGQE"
     misc_feature    complement(23463..23476)
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 19.47"
                     /tool="antismash"
ORIGIN
        1 caaagaaagt tgcatcatat tcgtaaattt atacggccgc ggaagccatc tcgctcctta
       61 tgacggctcc agctcgatcg taagacccgt ttgcgcaagc gaaacgaacg atggtagggg
      121 atagcttcgg gcaaggtcca ccccgtggga catatgagtg aaaatgaccc gcccaggaga
      181 aatttcgctt ataagctcca gcgcctcgac catatcgtag acggagcggg tcgcgggagc
      241 ggcttcttcc ttgtaaaaat tggtgcccaa aatgagcagc tgcagtccga acagcggggc
      301 tttctcttcg tcgctcagac gtatcgagtc gggacagtat acgaacgcat aggagggacc
      361 ggcggtccgt tcgaaccgat aggcgtaaga gtatccgttc ttgccatggc atacccgcca
      421 aggacggatg cgccaatgct cccattgcag gccgcccgcg cagtcgtgaa attgaagctg
      481 gttttgcagc cagggaaact gcttctggat cgtctgcagc acctccagcg gagcgtagag
      541 ccggcctttg cgcttcagcc agcggcaggc gtcggcccat tccggcagcc cgccgatatg
      601 atcgaaatgc gcgtgagtga tcagcacccg ctctacgaaa cgcttgcccg cgcgttccat
      661 ctgaccgcgc caatccggcc cgcagtcgac gagcagctcg ctgtctcccg catgcagcat
      721 aatagaggaa cggtaccgcc ggttactacc ggcccctctc gcttcgtcgc atatatcgca
      781 ggagcaatat acccgcggaa cgcccatcga atctcccgtt ccccagaatg ttaccgaatc
      841 tttcatgcat aactctcccg tatgaatgcg attttttcca gaataacagg aaatggatgg
      901 atcaacaagc ggattcctga acctcccgat tgacgcttgg cgcatctgcc tctacaataa
      961 tacccaaagt atgaaggagg aatggagcat ggcggaggat acaagaggca tcgactgggc
     1021 caagcggatt caggcgattg cccaggccgg gttagcctat tccagggacg ctttcgatct
     1081 ggagaggttt gaggaattgc gctccatcag cgtcgaaatg atggctgctt attcgggact
     1141 ggatattcgg caggtaaatc atctttttgc cggtgaaagc ggttacgcta cgccgaaagt
     1201 ggatattcgc ggagtcgtca ttcgcgacgg gaaaatttta ctggtacagg agaagaacga
     1261 cggagggtgg tctttgccgg gaggctgggc ggatatcggg ctgtcgccgc gggaaatcgt
     1321 cgtgaaggag gttaaggaag agtccggcta cgacgtcgct ccggtaaggc tgctggcggt
     1381 gctggaccgc aataagcatc ctcacccgcc tcatgcctac gacatctaca aaattttcat
     1441 ccaatgcgaa ttgacaggcg gccaggcgcg ggcgagcatc gaaacgagcg acgtcgggtt
     1501 ctttgcccct gacgatttgc cgcagctgtc gaccgaccga attaccgaat cgcagatcga
     1561 gctgctgttc cggcaagtgc gcgagcccgg cgaagcggtc ttcgattaat cggcgggagg
     1621 gtatcgggtt atggcaagcc ggctgctggc acgctttcat cactttctgc tcgggacgag
     1681 cctgcaaaac aagctcatca tattttttct tccgctcgcc atcattccct tgtcgatatt
     1741 aggaaccttt tcctattaca aatcctcgca ggtcgtacag acgcaggttt gccaaacgat
     1801 tctggagagc ctgtcccagg ttaactacag cctgaactat tttgttaaag atatcgaaca
     1861 attaacgatg tatatttaca gcaaccgcga gattcaggac gtgctatcga agagctcgga
     1921 ccgcccgctg gcggagaagc atcaggatga gaaacggatt caggatttgc ttgaaacgtt
     1981 cctcggcttc aaaagctgga atattgcgat ttatttgctg ggagagaacg gcgaccgcta
     2041 ttttacggga aatttgctgc ccagccagta tgacgattac aacgtcaact gggggctgtt
     2101 ccgcaaaatg agcctggccg gcggcaatgt tgtctgggat acccactaca gcatgaagaa
     2161 gacggaggac ttcggcatcg ttctaagcag cggcaggctg ctgaagaaga tcgagaccag
     2221 ccagccgctc ggctatatga tcgtcgatat tatggagaac gctctggcgg ataaatacaa
     2281 taaggcgcat ttgcagccgg gagggcaaat gctgcttctc gaccggggcg gctacgtcat
     2341 ctccagcacc ccgtccaagc atatcgtcgg tacgaagctg aacgagcctt atctcgatca
     2401 ggtgctggca ggcagcaaag gcttcttcga gctgcagggc gttagcggtg cgccgccggc
     2461 gatggtcgtc tacgatacgt cggagatgac gggcttcaag ctggtcagcg tagtgccgat
     2521 agagatgctg accaaggaaa gcagcagcat cagaaatctg acactgtacg tcatcatctg
     2581 cttcgggatc gttacgttct ggctcgccta cgtgctgtcg gtgacgatta cgaagccgct
     2641 gcgcaagctt aagtcgctga tgtacttggt cgagaacggc aatatggatg tcgcttttcc
     2701 gtccaaatac cgggatgagg taggacagct tggcctcagc ttcaacaaga tgctgcttcg
     2761 catcaagcag ttgatcgacg aagtgtacaa gaagcagctg atggtgcagg aggcggagat
     2821 caaggcgatt caggcgcagt tcaacccgca ttttctgtac aatgcgctcg actccatcaa
     2881 ctggatggct cgcatccaca agctgcccga catcagccag acggtcgttt cgctgggcga
     2941 gctgctgcgc ttcagcattc gcaaaggcca gccgttcatt caagtgaagg aagatatgca
     3001 gcagatccgc aactttctcg tcattcaaaa aatgcggtac ggcgataagc tcgaagccga
     3061 gctggagatc gatgaggaga tcgagccgct gtatacgctg aagctgctga ttcagccgct
     3121 cgtggagaat gcggtgacgc acggtcttga ggtcaaaccg ggcaaagggc atctgtcgat
     3181 ccgcggtcgg cgcgtcggcg acaaagtgcg ctttgaagtg agcgatgacg gagcaggtat
     3241 gccccgggag cgggtggagc ggatattaag cggcaaatat gaagcgccgg acgggcgcag
     3301 caccggcatc gggctggaaa acttgcgcaa gcggctggag ctgtatttcg gcggcaggta
     3361 ccgcctggac attcggagcg aagaaggaca aggaacgacc gttacggtcg aaattcccgt
     3421 catgcggaca gcaggagagg atcaacatgt ataaggtgtt tcttgtggag gatgaatggc
     3481 tcgttctgca agggctgaag ctgacgattc cctgggagga gctgaactgt gaaattatcg
     3541 gcgaagcatc tgacggccgg acgggagccg agctgatttt gacggccaag ccggatattg
     3601 tgcttacgga tatccgcatg cccgcgatgg atgggattca gttagcggag caggtcgcgg
     3661 cggggctgcc cgggatcaag atcgtattcc ttaccggctt tgacgatttc gcctacgcgc
     3721 agaaggcggt aaagctgggg gcggcggact tcgtgctcaa gccgaccaat gcggacgagc
     3781 tcattcaagt gatcgggagg atcacgtctc agctggatac ggagcgcagc cggcgttcgt
     3841 ttcaagaacg gctggagcac cgggccaagt tggagcatcc gctaattatg gagaagatgc
     3901 tgtacgagtt gatgcaagat tatgccggac cgacgctgaa ggagctgttt ctcgagtatg
     3961 gggaatggtc ggaagcgggg gcggaaggag acggatttcc tccttaccgg ctgctgttga
     4021 tacaactgga cggtctatgc cgcgagtccg cggagcgcga gagacagctg gagcaggtga
     4081 gggaacaggc tcaggagctt tcagcgctcc cggtcgtccg catgagcgag aaccgctatg
     4141 cgcttattgc gaatcgccgt accggccgcg aggcgctgat ggaggctgcg gcagcgctgc
     4201 ttaggcggct gccggtttta acgcgaagct atgtaatagg ggtcagcgct ctgttcaccg
     4261 ccggcatcga gtcgcttccg gcggcttatc agcaagcgat gcgcgcgttg tatcagaccg
     4321 tctttctcgg ccgggagaca tggatatggt atgaagatat cgagagagag caggcggacg
     4381 agccggggag cgaagacgcc gttcaagaat ggatcgatct ggtaaaatgg ggccatgcgg
     4441 cgtcgattga agcccatacg gcggcatggt attctcgtct gcttcaccgt tatccggacg
     4501 gtctggaggc gcgaagacgc ttcttcgaat ttatcgtcgc gctgtattcg gcgctgctgc
     4561 gcgatcatga gctgcgcgaa atcgtgctgg ggagcgattt tctcctcgcc ttcgccgaac
     4621 ggctggagca tacgctggaa cgttcgctgg agctgctttg cgccatgctg gccgaatgga
     4681 acgggctgtt ggcggagcag ggcgaaaccc ggaagaaaag cggcttcgag gagatcgaag
     4741 cgttcatcca aagccattat gccgaagata ttacgctgca aggcatcgcc gagcgttatc
     4801 atatgagcga gagctatttc agccggttgt tcaaaaagca ggtcggcacg agcttccttg
     4861 agtatgtaac gatgattcgg gtgcggcaag cgaaggagct gctggcaaat ccgcggctga
     4921 aaatttatga ggtttccctg caggcaggct atcaggattc caggtatttc agtcaaatat
     4981 tccgcaagta tacgggggag acgccgaccg aattccgcaa gcggctcggt attgagccgc
     5041 tgccgctcta aaccggggat ataagccggg cgtatcccgg ctgccgcttg gcggtgctgc
     5101 ctgcatacct gcaaacgatc aacgggcagg ggcgccaaga agccggcgtc cgggaggcga
     5161 tgcggtcaga gcgtcagtcc gaatcgcttc agctcgataa atatttgctc cagctttttc
     5221 cccttgtcgg tgagccgata ctctacgcgc ggcggaacct ccggatatac ggtgcgggtg
     5281 acgagcccgt gctcctccaa ctcgcggagg cgcagtgaca acgtcttcgg gctgatcccg
     5341 tccagacatt tcagcagatc gctaaacctc atcgttcctt cgatcaacaa atcgcggata
     5401 attagaaacg tccatttggt tccaatcact tctatcgctt tgacgatggg acaaatgtcc
     5461 ccgagcgtcc ctttggtcag cgctagcggc tgctcacaac ccggttccac aggcatcgtt
     5521 ccttttcata agatggattg aaaccaacta tagcacaaaa ctatcttttc ggaaactatg
     5581 tgtataaaat gtcactactt ccgtaaatga agtatatgtg tatataatgt ctacgtgaaa
     5641 aacaaactga tgacagagca gattttagat aataaaccat tcggatggtt aactaaacga
     5701 tgaggagaga catgtgtatg ccgagtttat cttcttcttt ttccctcaag ggcctgcaat
     5761 taaaaaatcg cgtggttatg ccgccgatgt gccaatattc agtagaggcc aaagacggta
     5821 ttccgacgga ttggcatttc gtgcattacg tctccagagc ggtaggcgga acgggcttga
     5881 tcatcatgga aatgacggat gtcgagccgg acggacgtat tacggattac gatctcggat
     5941 tgtggtcgga cgatcaaatt cccgccttca ggcgcattat tcaagaggtg cagaagtacg
     6001 gcgccaaaat cggcattcag attgcccacg ccgggcgtaa ggcggaagat gcggagattc
     6061 ctgtaggccc ttcgaatatt ccggtcagcc ctgaattcaa aacaccgcgc gcactgacta
     6121 cggacgaggt caaggcgatg gtcgtcaagt tcaaggaagc tgccgtacgg gctgtagaag
     6181 ccggcgtcga tacgatcgag ctgcacggag cccacggcta tctgattcac cagttccact
     6241 ccccggcgat taataaccgg acggacgaat acggtcagga cttggcccga ttcggagtcg
     6301 aaatcattca ggcggttaaa agcgttatgc cggagaatat gccgctcatt atgcgcatat
     6361 ctgcggttga atatatggac gaaggctacg atctcggcca tagcattgaa atcagcaggc
     6421 ggtacaagga agcgggcgtc gacatgttcc atgtcagctc cggcggagaa gggccttccg
     6481 gctccagaaa gccgggcaat tatccgggct atcaggttcc gatggcgcgc gcgatcaagc
     6541 tggctctgag cgttccggta attgcggtag gcattcttga ggacgccaag ctggccgaag
     6601 cgaccgtcgc taatgaggac gccgatttgg tgggcgttgc ccgcggcatg ctgcgcgatc
     6661 cgtactgggc tgcgcatgcg attagggaaa caaccggcca ggttgctgcg ccgcgacaat
     6721 acgaaagagc ttattgaagc ttgctgcaaa ttttagtaaa taatggtaga cgtgcggcga
     6781 ttgttatggt aatctataag caataatccg gaagcaccgg tcggaaaagg tccgttggcg
     6841 gcatatgtcg caggcgggcc ttttttgttg ttaaggaaat gatacgcagc catatcctgt
     6901 ggatatccgg gtgctccccc gaaaggaatg tctacccata gaacgatcca gaggaagggt
     6961 taaacgccga tccagcttag gctggatgcg gacggaataa gcttcagagc atcacgtcac
     7021 ttttggggga ttggttcttg ccattgtatg aaatatgaaa acgatatgtt ttgacgggcc
     7081 aacgggttct gacggaagct ggcggacgcg gtggtttttt ttgtactgcc gctcgtcgtt
     7141 ttccaatcgg acggattgct cgaagcgcac aggcggcaat aaagccgcga tgtcgtggat
     7201 gacgccgcta acggaaaaat aggcagttga atcagtaaca acagcggatg ccgattcata
     7261 tgttgtcatg gagtattcga tgagcgccgt cgatcccgcg agaacaaacg cagctgagcg
     7321 gctcgcccaa aagaaaccgg attcagcttc gcttttgggg gcctttgttc ttttctattc
     7381 ctaatgcaga gtactctgtc ggcgtgacca cttaacctac ggaggatggt acaaatggga
     7441 gatttcaaaa aggatttgca aaagctgaac gtttccgata tcaaaggggg agcggtcaac
     7501 tcttggaacg gccaaaatca gcaggataca agaacctggc atacatggta caactgccat
     7561 aattgtcaca attgccataa ctgttatacc tgccataact gccacaactg tcatacctgc
     7621 cacaattgtc acaattgcca taactgtcat acctgccaca attgtcacaa ttgccataac
     7681 tgtcacacct gccataactg ccacaattgc cataactgtc atcattcata agccgccgat
     7741 ccagcgaaaa gcatacgatg ctgccgaagg ctctgcttac gcatgtcatt tcatgcggcg
     7801 gcagagcttt ttggcggtcg catcggttta acggagcaag tcccgtttgc catttgacat
     7861 gaaggacaag aaccttacat aaaatgacat gtagaacata cggcccgatg atgagctgga
     7921 ggaggagtac gatggttcag ctaaatcctt ctatgcgact gaaagtgaac cgagatacgt
     7981 tcgtgatgcc ggagcccgga ggcagcgtct acgttcggaa caacgcacgc tccttccgga
     8041 tggaagggga agccgccgat cagtggctgg agaagctgct gccggtattt aacggcgagt
     8101 acacgctggg cgaactgacc gacggtctcg cggagcctta tatcatccag gtgtatagca
     8161 ttgccgccat gctgcatgag aacggttttg tacgcgatgt tagcggcgat aagccgcatc
     8221 ggctgcctga agcgattcgg gagcgatacg gctcccagat cgaatttatc gagcagttta
     8281 ccgattcggg aggattccgg tttcagaagt acagacagac tcgtgtgctt gttatcggga
     8341 acggggagat gctggccgct cagacggcgg cgctgctgta ctccggcttg ccccgctttc
     8401 gcgtgctgat cggcgattcg aagacgaccg agcgaaggcg gctggaggag ctggctgcgc
     8461 atgcccgccg gtcggaccct gaggttgacg tggagctgac ggaacccggc ggcggggagc
     8521 tgccctcctg gaaggaggcc gtccaaggct tcgaagcggt cgtatacgca gcccggacgg
     8581 atgatccgga ggaactgcgc agggttcatg ccgcttgccg cgaggagggc aagctattcg
     8641 ttcccgcggt atgtctgccg cagatcggat gggcgggccc gctggtgcat ccggcggcgg
     8701 atgcttgctg ggaatcggct tggctccggc tgcatcgctc ggtgacggag cgagaccccc
     8761 ggcagcacgg ttattcttcg accgccggcg ctttgctggc gaatattgcg gccttcgaat
     8821 tgtttaagca cgtgacggaa gccgggccgc gcaggtcgag cggatcgggc caatgttatc
     8881 tgctcgatct ggagacgctg gagggggcct ggcatccgtt cctgccccat ccgctcgcga
     8941 cagggacact gggctcgatg ctcatgaaag actgggagca atggctggag gagaagagcg
     9001 agccgcagcc gggagtgtgg ctggcttgct tcggccgaat aacgtccaag gcattcggcg
     9061 tgctggacag ctgggacgaa gaagagcttg tccagcttcc gctggcggtt tgccgcgcgc
     9121 aggcggccga cccgttgtcg gatgggccgt cggagctgct gccgtccgtg ctctgcgccg
     9181 ggctgacgca tgaagaagcg cgcagggaag cgggcctggc gggagtggag gcttacgcgg
     9241 cgcgatggac ggaggtgtcc ggcgccgggc ggtttgcagg caaggagccg gacattacgg
     9301 cgattgcggc ggagacggct gagcttatcg gcgtcggtgc cggagagacg gcggcggaag
     9361 cgatctcccg cggcctgtat aaacggctgt ccgcggagct cggccgccgg cttgacgcct
     9421 cgccggtcgc gatcgccccg gcgcagccgg atgcggtaga ggatgcccgc tgccgatttt
     9481 attttcaagc gatctccctt atggggggag cgccgcagct tgggatcggc gaggagctgt
     9541 acgggtttcc ggtcgtgtgg gttcgctcgg gcgaccggtg gtacgggagc acgggcctca
     9601 atcgaacctt ggcgctgcgc gaggcgctga agcgggcggc cctcgcccgg cagtgcgagg
     9661 agaattgttc ggcgggcgag acggtgtccc ggaatcagcc gcaagagccg ccgatcgggg
     9721 aacaggcgca gcatcctgcg caggaaggcg ggcggcttca gggtccggcg ccggttcaag
     9781 taagatcgga ccgggcggtc catatcaagc cggacgaacc gcttcggctt gccgttccgc
     9841 ctgcggagga cggggatacc gccgccatcc tgcattcggc cttgcacgtg ctgaacaggc
     9901 aggggctgcg gcttgaggtc atcgacatgg cggtggagcc gtttatgcga gaagggcttg
     9961 ccggtgtggt cggcatcctg ctgcgtgggg aggagatgcg gtgagcgcac ttgttgtcat
    10021 tgtaggcgag gggcagctgg cggaccttgt cgccggcgat ttggcccggt ctttccgggt
    10081 cgtccgccgg cagagcataa gcggcggcat ggccggcgcc gatctggcgc tgacgctgca
    10141 cgacggctgg cagccgggaa tccatctgcg ggcggaagag gagctgccgc ccgcaggaat
    10201 tccttggctg cgcgcttgcg tcttgttcgg cgaaggcctt gtcggcccgc tcgtcaagcc
    10261 gggagcgccc ggctgctcgc aatgcgccga tgcgaggctg cacatggccg ggcaggaccg
    10321 cccgagcatg tggaggctgc ggcgcaagct ggccgaagag ggcgggacgg agcgggacgc
    10381 ttgggatgcc cgcggcggca tgctgcagct ggcgctgctg acagcggccc agtcgcgcaa
    10441 ggcgctggaa cggccggatg aagccgattc cggcctgatg catatcgtca atatgcatac
    10501 gctggccata tcgcggcacc gggtgctgcc cgatgcgcat tgccccgtgt gcagccggat
    10561 tcgggacgac acggaagcgg cagcccgcat cacgctgcag ccgaatccca aggagcggcc
    10621 ggacagctac agaatccgtt cgatggagga actgagggac gctcttgccg ccgattattt
    10681 ggattcgcgc acagggctgc tcaatgcggc ggtaaccgat ctcgtctctc ccttcgccga
    10741 cgccagcgtt aatctgccgc tgatgaacga agatgtcggc gcggccggcc ggacgcattc
    10801 ctatgaggcc agcagactga ccgccatgct ggaagggctg gagagatact ccagcatccg
    10861 gccgcgaggg aagcggacat ccgtctatgg gagctatcag gagctgcggg agcaggcgct
    10921 ggacccggtg aagaccggcg tccattccgc cgagcagtac gctctgcccg gctacccgtt
    10981 tcggccgttc gatcccgaag cgcccctgcg ctgggtctgg ggttactcgt ttctgcagga
    11041 acggccgatt ctcgtgccgg agtcgctggc gtattacggc tcgggaggcg ggcagagctt
    11101 tgtgtttgag tcgtccaacg gctgtgcgtt agggggaagt ctggaagagg cggtgctgca
    11161 cggcattctt gaggtagccg agcgggatgc gtttctgatg acttggtatg cgcgtcttcc
    11221 tttgccgcgg ctcgatctgt cgactgcggg cgatgcggag ctgaatctga tgcttgcgcg
    11281 gctcgaagcg gtggcggact tcgacgtgcg gttctataac gcgacgatgg aatacggcat
    11341 tcctagcgtc tggggaatcg ccgtgaaccg caagcggcaa ggcttgcggc tcttgtgcgg
    11401 ggccggtgcg catccggacc cggtgcgggc ggtcaaaggc gccgtgcacg agctggccgc
    11461 tatggcgctg aacctcgggc cgaagcttgc cggggatttg gaacgctacg aggcaatgct
    11521 tcgcgattct tccttggtcg caaggatgga ggatcattcc ttgctctacg gcttgcccga
    11581 ggcgcaggag cggctcggat ttctgctgga cgacagccgt ccggcgcgtt cgttcgcggc
    11641 ggaattcccc gccaagaaga tctatgccga tttgacggat gagctgagag cgctattgcg
    11701 gtcgctcggg cgtagacagc ttgacgtcat tgcggtggac gtcaccgctc cggaaatcgc
    11761 ccgcaacgga cttttctgcg taaaagtgct gatcccgggg ctgattccga tgacattcgg
    11821 gcattcgttc acgcgcctga ccgggctgga acgcttattg accgtaccgg cggagctggg
    11881 ttacgcagat aggccgctca cgccggatca gcttaacgaa ttcccgcatc cgtttccgta
    11941 aacggcaggc gaaccgcggg aacgaaggag gcgtttgcga tgaatcggct ggatgcattt
    12001 atgcacgatc tgcatttcca tatcgaccgg acgaagccgc cggaccgcgt cgtcgattgg
    12061 gaagacggac cgctggcttt taagctgtac cgcggtctgc cggtttttcc gcttgcggcg
    12121 gacatccctc tctccatagc cgcggaaggc gcaaacgcgc cggggcgacg gatcggcctg
    12181 cgttcgctcg gccatctgct atggtatgcc tacgggctca cggagctgtc ccattcggtg
    12241 cagagctcct tttcctccgg gacggatctg ttccagatgt atcgccggtt cgccccttcc
    12301 gggggagcct tgtatccgag cgagctgtac gtctatttga aactggatac tttgccggcg
    12361 ggcgtatatc actacgatgc ggcacatcac cggctagtgc tgctgaggga aggagactgc
    12421 gacgctttcc tgcaacgggc tttgggggag cggtttgaac ggtcccgctg ctgcggcgcc
    12481 gccttcgtct cggcgatgtt ctggaaaaac ttctttaaat acgacagctt tgcgtaccgg
    12541 ctgcaggggc tcgatgcggg aacgatgatc ggacagctgc ttgaagcggc cgaacgcttc
    12601 ggcgtagcta cggcagtcca ttttcaattc gcggaccgcg cgattcatca tttgctcgga
    12661 ttatccgagc ttgaggaaag tgtctatgcg gtggttgctt tatcggatgc gccggctccg
    12721 tgtccgccgt gtctgggaac ggagccggag gagcgcggcg ggtcagatcg gtcaggacgc
    12781 tccgaacggc agagcgagga cgggcggtct gcggaagcat ggtaccggga gctgccgcct
    12841 gtcagtcacg agcattatgt ccgctcgaag aggatcaagc cttacccgct gctgctggag
    12901 atgaacgaag cgtcgatgct ggcgtcggtt tccgcaccgg cgctggaggc tttcgcccgg
    12961 cctccggccg cacggcgcaa gctaccgggc atagaaggcg tggtgcggct tcccgcggcg
    13021 gagcgcctcg cctacgattg ggcggcggcg agccggaggc ggttctcgcc cgacaccgat
    13081 ttcgcgctcg ggcccgtttc cttggggcag ctctccgcgc tgctgcgcga aacggcggca
    13141 tcgctgcgct gccgctgcga tcttgacggc ggcgttttgc aagagcagcc caggcttagc
    13201 ttgtacgtat gtcttcacca tgtggaaggg atagaagacg gagcttatgt ttacgacatc
    13261 cccgagcatg cgctcgtagc cgtccgggag ggcgatctca gactgtggct gcagatcggg
    13321 atgaattcgg acaatgtgaa tttgctgcag gttccgcttg tgtttcatgt ggcgggtgac
    13381 cgcaaccatt atacgcaaga gctggggtac cgcggatacc gcattcagca gatggaggcg
    13441 gggatgctcg ttcagcggct gctgctggcc gcttcggctc tggggcttgg aggacatccg
    13501 ctgcttgatt atgacgccag gctgtgcgac gagctgtacc ggctgccggc cgagggactg
    13561 acgagtctga ttcaagtccc gatcggtcct tatcgcccgt gtcccaaact ggcgggaggc
    13621 ctgcacggct aaaacatcga aggggagccg ccggagaggg ctccccgcca aatatctgaa
    13681 gccgcttcga agccaaagcc ccgctatgcg gggtttattt attgtttagg aaatgatgcg
    13741 cagccatatc ctgtggaaat ccgggggcac ccccgaaagt aaagtctacc catagaacga
    13801 tcccagagga agggttagac gccgatccag cttaggctgg atgcggacgg aataagcttc
    13861 agagcatcac gtcacttttg agggatttgt tccgcgtgtg cgtgcgttta agcggcgccg
    13921 ccgtcgatcg aggaacgccg gctcctcttt ttttcgtaaa tacaaggctg aaaatgctcc
    13981 ggcagacggt gaatcgcaat tttagctttc ggtaaccgcg tagggcaagg tatactaaag
    14041 aggaacagca tgttgattcg gcctaataag ataaggctcg ccgcatgaca aacagtaagc
    14101 gtttgcatgt gcctgcgggg gactcgccgc cgccggaaaa tgtcgaaacg tgacgtaata
    14161 agccgacggt caaggcggaa gcgtccgctt cgacggggga acggacgagc gcttatcgtc
    14221 aataatattt ctacttggag gtaaacctta tgctaaggag aaacggggct aaccgtacga
    14281 gagccagaca tcggttattt gcgcgccttc tcatcccata tttggtcttc ctgatgctgg
    14341 cgatcatgat cgggctgatc atttatcaga agacgatcgt tctgattgag aaggaagcta
    14401 ctgccagtca tatgaatttg ctggagcaga gcaaggacat tctcgaccgg agacttgagg
    14461 agctcgcttc catagcgcag cagctggcgg ccgatacgcg cattatgcaa tttcaatccg
    14521 tgaccgatcc atacaaaggg acgaacacgt tccggattat ggatacgaac aaaagcttgt
    14581 acgattacaa gctatccaac aattttgtgt tcaactacta cgttttgttc aaaaacagcg
    14641 agatggtatt tactcccggt gcaagctact cgtttgagca tttttttaac agagtagcca
    14701 attacaaagg gatgaattac acgagctggt acgccctgat gtcgagcgat ttccacatga
    14761 ggaaggtgct tcccgcccag gaaatcagta tggaaggcgt cccttattct atgctgactt
    14821 atatccaatc gctcggttac cccggcaacc cgcagggagc catcgccatt atggtcgatc
    14881 agcgggagat tcaaaagctg ttccaggggc tggatatttc cagcggcggc tgggcttaca
    14941 ttgtcgacaa ggaaggtcaa atcataagcg cgctgtctcc cggagacgct aacacgctgc
    15001 cgatcgagct cggcaggctg gccggggatc gaggcgtcgt cgagcagagg attgacgcca
    15061 agccgatgat ggtcacttat acgaaatcgt cctacaacgg ctggacctat gtggtggggc
    15121 agccgaccgc catcgctctg ggcaaagtcc ggtatatcca gaagatcatc gtaacttttg
    15181 cctgcgtgtt tctgctcgcc ggcgtgctgg ccgcctatgt gcttgcgtac cgcaacagca
    15241 agccgctgcg cgcgctgatc aatacgatta tggagaagac ggatgtgctg ccgcagcaaa
    15301 gggatgcctt cggcatcatc ggggagacgg tgaacgggct atttcaaaat aacgacaagc
    15361 ttaaagcgga gatcaagcag caggttcccc tgctgcgcgc ggcgtatttc cagcggctgt
    15421 tgaacgggca attcgtatcg tcgcgcgatt tcgacgcgct gctgaagcat gtggggctcg
    15481 atctggtggg catgtcttat cgggtagcga tcgtccgcct gcgcggattc gataaaggtt
    15541 acagcgacga tctgctggag gagctggaca ggagccgggt gcttgccaaa gaactgctga
    15601 gaaggacgat ggacgaggac ggctttgtct gcgaaatcgg cgaggatcaa ttcgccgtcc
    15661 tgtttactta caagctggat gagcgggagc cttacaaggc ttacgtcgag gcgaggctga
    15721 aggaagccag agatgagatc ggccttcagt taaagctgca gtcggtctat ggggtaggcg
    15781 gcgcctgcga cagtctgacc ggcatctcca gatcgtacga gcaggcgcgc gaagcgttaa
    15841 acgcgcagtt atggagcaac caggaaggcg gcttatggtt cgacgagctc ccggcggata
    15901 tggccaatta ctatcttccg caggatgtcg agacccggct catccatttg gcgaaggcgg
    15961 gcgaccagac cgaggttcag cggacgctgg acgagctgta ccgcgaaaat ttcgaactga
    16021 ggcagctgcc cattgccgtg atgaagctgt ttatttttga aatgtgggga tgtcttgtca
    16081 agctgctgcc gcagatggat ctggaccagc agacggccta taaccggatg tcagcgctca
    16141 gcggagcgaa cgagtcctat gaaagcatga gcaagagcta ccaggcgatt cgcgatacgt
    16201 tccaatgggt ttgcgaaagc gccaacgagc ataagaagag ccagaacgtc gagctgatcg
    16261 acagcattat cgggctgctg cagagctcct atatggacag cgagctgtgc ctggatgtcg
    16321 tagccgaccg gattcgcatc tccaaggtgt atttatcgca gtttttcaag gaacaaaccg
    16381 gggtgaactt ttccgattat ttggaaagct tgcggatgga cgaggccaaa gcgctgctgc
    16441 agacgacatc gctaacggtg aacgacattt ccgaccgcgt cgggtacagc tcctccaaca
    16501 cgttttgcag ggcgttcaaa cgtttgcatg gggtcagtcc gaccgctttt cgcaagctgg
    16561 ttttgaagaa gctgccgggc taaagccggt ttttgcccgc tgccgtcata gggtgagttg
    16621 gcgttccgct gcagcgttta tacgcctaag aacgccgctg cagcggcgta ttctttattt
    16681 ttgcacaaaa aaaatcgaac tgcacaagcc gattcctaac ttttgcacaa caatagagcg
    16741 ctttcttctt tcgctccgag ccggatgctt ctatcatgaa gctattcgaa cgaaaggggg
    16801 aacagagaaa gatgaaagcg gttgtatccg taaaaacaga aatgaaggcc tccacgaaca
    16861 aaaaacgtca accgttttcc gtatggaagc aaatgaagcg gagctggcag ctgtacgtgc
    16921 tgcttacgct tcctgtcctc tatgtccttg tattcaaata ttatccgatg tacggggcgc
    16981 aaatcgcctt caaggattat attgcttcca aggggataac ggggagcgag tgggtaggtc
    17041 tgaagcattt catccggttt ttcaactcgt acgaattcgg caagctgatg aagaacacgc
    17101 tcatcatcag cgtatacagt ctgctggccg gtattccgtt tccgattctg ctcgctttat
    17161 cgcttaatta tgtgaaaaac cggctgttca aaaaaacggt tcagatgatt acctatgcgc
    17221 cgcattttat ttccgtcgtc gtgctggtag ggatcattct ggagctcttg gacccgcgca
    17281 aagggattgt caacctgctg ctcggcaagc tgggcgtgga accgatcaat tttatggccg
    17341 tgccggaata tttcagctcg atttatgtat ggtccggcat ttggcagaac gtaggcttct
    17401 cctgcatcgt ctatttggcg gcgctggcgg gtgtggaccc ggcgcagcat gaagcggcgg
    17461 tcattgacgg agccaacaaa tttcagcgta tgcggcatat cgatctgccg agcatcattc
    17521 cggtcatgat gatcctactc atcctgaaca ccggcaatat tttggacctt ggcttcgaga
    17581 aggtgctcct gatgcaaaat tcgctcaacg cgcgcacctc ggaggttatc gatacgttcg
    17641 tctataaggt cggtcttgct tcccaggcaa tgaactattc ctattcgacg gcgatcaacc
    17701 tattcaagtc ggtggtcgga ttgattctgc tgctgaccgt caaccagatt gcgcgaaaaa
    17761 ccaaacagga gagcctatgg tagcgcgggc gaagggagga gaccgggatg gagcaaacta
    17821 acattaagga agccagcgcg gatcggtggt ttaatgccgt caattacatc gtcctaatgc
    17881 tgttcctgat tacggtgctg tatccgctat tgtttattgt aagcgcatcc ttcagcagtc
    17941 cgggcgcggt catgtcgggg aaggtgtggc tgtggccggt cgagccgggg ctgcaaggct
    18001 atgcggcggt gttcaaacat aagcttatct ggagctcgtt tcgcaattcc gtcttctata
    18061 cggtggcagg gacgctcatt aacgtcgcgc tgacggtgat ggccgcttat ccgctggcgc
    18121 gcaaagattt gtacggcaaa aatgccgtga tgctcctgct cgtgttcacg acgatttttt
    18181 ccggaggact gatcccgagc tacattctcg ttaaggatct gggaatgctc aacaccgtat
    18241 gggcgatgat tttgccgagc gcgatgagcg tgttcaacgt cattattgcg cgaacgtact
    18301 tcaagacgac gataccggaa gaattgctgg aggctgcgca gctggacggc tgcaacgact
    18361 tcaagttcgt atggaaaatc gtcattccgt tatccggccc gattatcgcc gtcattatgc
    18421 tgtattcggc cgtaggctac tggaatcaat atttcaacgc gatgatttat ttgaagcagc
    18481 cggctttgta tccgctgcag ctcgtgctgc gagaagttct tattcagaac gaggtcgaca
    18541 ccagcatgct cgccagtctg gaagatcagg caaagatgga gggcatgcgc tccctgctca
    18601 aatattcgct gatcgtcgta tcttccttgc cgctgctggc ggtgtatccg ttcgtgcaaa
    18661 agcatttcgt caaaggcgtt atgatcggtt cgttaaaagg gtaaatcggc gctagtaagc
    18721 tgggctgggc aaaaatcaaa gggggtttat acaaatgaga aaatggatga cggcaggctt
    18781 ggtcttaaca ctcggcaccg ctgcggtatt gagcggctgc gcggataaag gggagcagaa
    18841 ggaaggcgcc gactcggcgc agcaggcgaa ggtgaatccg gccggccaat tccctatcac
    18901 cccggaaaag acgacgttga aggtgctcgt gaagggcagt ccttttgtcg aggatttcgc
    18961 tacgaatgag tttacgaaat ttttggagga gaagacgaac attcatatcg aatgggacgt
    19021 cgccccggag aaatcggcta cggaaaagct gaatctggtg ctcggaagcg gagacttgcc
    19081 cgatgtcatt atgggcttcg gcgtttcgcc tacgcagcag ctgatctacg gaagccaggg
    19141 agatttccta gatctcagcc cgtatatcga aaagtacggg gtggagacga agcggatgtt
    19201 cgagcaggtg cccggcgtga aggacgcaat tacggcgccc ggcggcaaaa tatacgccct
    19261 gccgatggtg aacgaatgtt tccactgttc cgcatcgcaa aagctgtgga tctacaagcc
    19321 ttggctggat aaattggggc tgtcggttcc gaagacgacc gatgagctgt acgaggtgtt
    19381 gaaggcgttc aagacgaagg acccgaacgg caacggcaaa gccgatgaaa tcccgctggc
    19441 cggcgctgcg gtaggcccga acgtcaatgt cgattcgttc attatgaatg cgtttatcct
    19501 cgattccagc gcgtacggcg tcggcaccaa caactacacc cgtttgttcg tcaacgacgg
    19561 caaggtggat gtgccctaca acaagccgga gtggaaggaa gggctcgctt atatgcacaa
    19621 gctgtacgcc gagggcttga tcgcgccgca aacgttcacg caggacaggg atcaggcgag
    19681 acaaatggga gagaatcccg atgtcaacat attaggtgcc gagatggctc agcataacgg
    19741 cgtcttcacc accttcagcg gacctagcgg ccgctggctc gaagtgacga gcgttcctcc
    19801 gcttaaggga ccgaaggggg ttcaggtcac gccgatcaac aacagcatag gccaagggcg
    19861 ttatattatt acgaaggcga gtaaaaatcc ggacgcggcc ttccgcctcg cggacatgct
    19921 gtacaccgaa gagatgacgc tgcgcgagac gatcggccga ccggatgtgg agtggaagta
    19981 tgccgataag ggagaaatcg gaattaacgg caaacaggcg atttggaaga aaaccggcgc
    20041 cgtcctgcct accgtgcaga acgtaacctg gtcgcaaacc gcgccgacgc tcagaacgaa
    20101 tgatttccgc ctcggtcagg tggccgatcc gaataatccg caggaaacga ttttgtacaa
    20161 cgaaacgatg caaaactacc agccttacaa acaggatatg aagacgttcc tgccgcagct
    20221 gttcttcacg aacgatcaag cgatggaact ggccgacctg gagaagacga ttacggacca
    20281 tgtgcaggag atgatcgcgc gcttcgtgat cggcgatgcc agtctggata aagattggga
    20341 tgcctatttg aaaaacttgg acaatatgaa tttgaagcgg tatttggaaa tttatcagac
    20401 ggcatatgac gccaagatga aaaaatagac ctgaagacct gatggccgga taggtcggca
    20461 agcccctttt tcgcggttcg tgtttagcga agctgcgaaa agggggtttt ttattgttta
    20521 ggaaatgatg cgcagccata tcctgtggaa atccggggct cccccggaag taatgtctac
    20581 ccaaagaacg atcccagagg aatggttaga cgccgatcca gcttaggctg gatgcggacg
    20641 gaataagctt cagagcatca cgtcactttt gggggatttg ttcttcattg tgccgcggtt
    20701 tcgcggcgag tttttttctt ttcccgcgca gttacggtac aatagatgtg cattgctgcc
    20761 gtaagggaga aaataacgat ggaacataca ctgaagtccg aagcggatat agccaaggtt
    20821 tgcctgctcg ccgggaaaat catgctgcaa agcggcggcg aaacctatcg cgtggaagat
    20881 acgatgatcc ggattgccgc ttcgtttgga attgaaaatt cgcatagcta cgtgacgcct
    20941 acggggattt ttttctccat cgacgggacg gagccggcca cgcagcttat ccgcattatg
    21001 gagcgcagca ccgatctgcg caaagtggcg ttagtgaacg atatatcaag aaaaatcagc
    21061 tccggagcga tgacaacggc ggaagcttac caggcgctta aggaaatcga ccgggcgaac
    21121 ttagcctacc ccctgtggct gcaaattgcc gcagcggcgt tggcgagcgg ctgcttcctc
    21181 attatgtttc aaggaacgag ggcggatttt ataccggcga tggtgaccgg cgggctggga
    21241 ttttgggcgt atttgcttgt ccagcgctgg gtcgtcatca agtttttcgc cgaattcgcc
    21301 gcagcgctgc tgctcggctc gctctcgttc ctgctggtgc ataccggctt tggccgcgat
    21361 ttggataaaa tcattatcgg ctcggtcatg ccgctcgttc cggggctgct gattacgaac
    21421 gccgtaaggg acttaatggc aggccatctc gtatcgggct tgtccaaggg tgcggaagct
    21481 ttcctgacgg ccttcgcgat cggctcgggc atcggcttcg tgctttcatt ttatgcggca
    21541 ggttaaaccg gcggccggag gggaggaacg cgtttcctat ggttatcgag cagctcgtta
    21601 cgagctttat ttcatcagcc gctttcggcg ttttatttaa tgtgcctaag aaaaatttgc
    21661 cgcaatgcgg gtttgtcggc atgctgggct ggctgctgta tatatcctgc atgaaagctt
    21721 gggacaatcc gatcgtctca agcctgatcg cggcgttttt cgtcacggtg ctcagccagt
    21781 ttctggctaa ggtgtacaag accccgatca tcatcttcag cgtatcgggg atcattccgc
    21841 tcgttccggg agggctggcc tatgacgcga tgcgcaatgt cgtggaaaat cagtatgacg
    21901 tcgccgtcca gctcgcggcc aaagcgttta tgatctccgg ctcgatcgcc atcgggctcg
    21961 tattctccga ggtgatcaac caggtcatac gcagatcgag gctgtaagga tgacaatata
    22021 ttttccaata tatggatata tgggtcgcgg gaggggagag cctgtacagg ttctcctctc
    22081 tttggcgatt cagggcaaaa atttcaacac atacgaaatt tcatcgcatt gaaagcgctt
    22141 atcttcgaca gtatagttaa agctataaaa gcggttattc ataacgcata tggaggggtt
    22201 attacaatga gaaaagcggt tacaacggtt cttgcttccc tgctgctggt cacatcgctg
    22261 gtaggctgcg gagcgaagga aacgccgagc gcgaagcctg cggaaggcgg tcagcagccg
    22321 gcggcgcagc agtcggcgcc gaaatcgggc ggcaagctga cgctctattc gccgaatgcg
    22381 gcggaagtga acaatccgat catcaaggaa ttccaggatc gcacaggcat cgaggtgcag
    22441 ctgatttccg gaggcacggg cgatttgctc aagcgcgtgc aggccgaagc ggccaacccg
    22501 ctgggcgacg tgttctgggc cggcggagcg gattcgctgg aggcgtacaa gaaatatttt
    22561 gaaccgtaca agaccaagga atacgacaat ctggctccgg aatatgtaga caaaaacaac
    22621 gtatggacgc cattcgcggc gctgccgatg atcattatgt acaacaaaga actggtgaaa
    22681 gaaggggagg agccgaaggg ctggaacgac ctgctcgatc cgaaatggaa gggtaaaatc
    22741 gctttcgccg atccggccaa atcgggctcg tcctatacgc agctgattac gatgctgacg
    22801 gccaacggca aggacaacgg ctggggattc gtgaagaaat tcgtgcagaa cctcgacggc
    22861 aaggtgctct ccggttcggg tctcgtctac aaaggcgtag ccgacaagga gtttgcgctc
    22921 ggcgtaacgc tggaggaagc ggcgcttaga tatgtggaag gcggggcgaa ggtcggcatc
    22981 atctatccgt ccgaaggcac ctccgcggta ccggacggct gcgctatcat caagggcgcc
    23041 aaaaacatgg atcaggcgaa gcagtttatc gacttcctcg taagcaaaga cgtgcaatcg
    23101 ctcattcaga aagaattcaa acgccgctcc gtccgcaagg atgcggaggt cgtgcaaggg
    23161 atcgcgcagg cgaaggacat caagctggtc gactatgact tcgattgggc ggcaagcaag
    23221 aaggacgaaa atatcaaacg tttcggtaaa attgtaaccg gtcaagaata atcggaagtt
    23281 ggggtggtgc cttaaccaat gcgcatgttc agccgtttca tgaacctgct ctaacacggt
    23341 gaaggcacct ttctttatgc aacggcacgg atcggccgac cgtttctccc atggcgggcg
    23401 cgggacggct tctcctttcc gcagttcaga cggatgtgtt gttcaaacaa ggaggttttc
    23461 catttatgca aaaaatcgta ttcgatcacg tgaccaaata tttcggttcc gccaaggcgg
    23521 ttaacgatgc ccatttgacg atccaagaag gggagttttt cactctgctc ggcccgagcg
    23581 gctgcggcaa gacgacgctg ctgcgcacga tcgccggctt ctaccgtcag ga
//
