LOCUS       NZ_CP027059            20798 bp    DNA     circular CON 16-JUN-2024
DEFINITION  Paenibacillus konkukensis strain SK3146 chromosome.
ACCESSION   NZ_CP027059
VERSION     NZ_CP027059.1
KEYWORDS    RefSeq.
SOURCE      Paenibacillus konkukensis
  ORGANISM  Paenibacillus konkukensis
            Bacteria; Bacillota; Bacilli; Bacillales; Paenibacillaceae;
            Paenibacillus.
REFERENCE   1  (bases 1 to 7969064)
  AUTHORS   Jung,H.I., Park,S., Niu,K.M., Lee,S.W., Kothari,D., Yi,K.J. and
            Kim,S.K.
  TITLE     Complete genome sequence of Paenibacillus konkukensis sp. nov.
            SK3146 as a potential probiotic strain
  JOURNAL   J Anim Sci Technol 63 (3), 666-670 (2021)
   PUBMED   34189514
REFERENCE   2  (bases 1 to 7969064)
  AUTHORS   Kim,S.-K., Jung,H.-I. and Lee,S.-W.
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2018) Department of Animal Science and Technology,
            Konkuk University, Neungdong-Ro, Seoul 140701, South Korea
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: 26-MAY-2016
            Assembly Method                   :: other v. HGAP
            Expected Final Version            :: yes
            Genome Coverage                   :: 7968964.0x
            Sequencing Technology             :: PacBio
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_023523925.1-RS_2024_06_15
            Annotation Date                   :: 06/15/2024 05:36:52
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 7,013
            CDSs (total)                      :: 6,868
            Genes (coding)                    :: 6,761
            CDSs (with protein)               :: 6,761
            Genes (RNA)                       :: 145
            rRNAs                             :: 13, 12, 12 (5S, 16S, 23S)
            complete rRNAs                    :: 13, 12, 12 (5S, 16S, 23S)
            tRNAs                             :: 104
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 107
            CDSs (without protein)            :: 107
            Pseudo Genes (ambiguous residues) :: 0 of 107
            Pseudo Genes (frameshifted)       :: 45 of 107
            Pseudo Genes (incomplete)         :: 72 of 107
            Pseudo Genes (internal stop)      :: 13 of 107
            Pseudo Genes (multiple problems)  :: 20 of 107
            CRISPR Arrays                     :: 10
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 10:26:11
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 93142
            Orig. end                         :: 113940
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP027059.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            Bacteria and source DNA available from Soo-ki Kim.
            Genome not circularized.
            This genome has a base modification file available.
FEATURES             Location/Qualifiers
     region          1..20798
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene"
                     /region_number="1"
                     /rules="(PT_phytoene_like or phytoene_synt or Lycopene_cycl
                     or Lycopene_cycl_fung or T1TS or T1TS_KS or T2TS or TS_UbiA
                     or TS_Pyr4)"
                     /tool="antismash"
     cand_cluster    1..20798
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /kind="single"
                     /product="terpene"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..20798
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:10798](+)"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..10798
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
     misc_feature    120..135
                     /note="TFBS match to CRP, Cyclic AMP receptor protein,
                     confidence: medium, score: 17.19"
                     /tool="antismash"
     misc_feature    complement(324..333)
                     /note="TFBS match to AbrC3, Antibiotic production
                     activator, confidence: strong, score: 17.62"
                     /tool="antismash"
     gene            complement(933..2189)
                     /locus_tag="SK3146_RS00400"
                     /old_locus_tag="SK3146_00077"
     CDS             complement(933..2189)
                     /GO_function="GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA]"
                     /GO_function="GO:0004673 - protein histidine kinase
                     activity [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_process="GO:0007165 - signal transduction [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1003: sensor
                     histidine kinase"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006038386.1"
                     /locus_tag="SK3146_RS00400"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SK3146_00077"
                     /product="HAMP domain-containing sensor histidine kinase"
                     /protein_id="WP_249863196.1"
                     /transl_table=11
                     /translation="MFDKLRNRLLLMNMVIISIIMLGAFTIIYTITYQNVRKDIMMDLQ
                     HTADASNKKDGPIGKKGGPAGPRGGDMPGEDHMRSVSFSLQTDKQWSITETNSRFDMSS
                     DFYAAAVKKAAEHPEKISQFTLNGTRWAYSVINNQSGYFIVYMDVTDRQTILTNLVYTF
                     SAVALFMLGIIYLTSRYFADRSIEPVKEAFEKQKRFIADASHELRTPLAVINTNADVLL
                     ANGEDTVNGQAKWLHHIKAETERMKTLTRDLLYLTEMDDAKPRMLYVPFDLSEAVESVI
                     LTMEAVIFEKDLALDYDIEPELTVTGSSEQMKQVAMILLDNAIKYSNPKGSIVLALKKH
                     QNHVRLTVSNTGPGIPAEHLDKIFDRFYRADPSRSRQNGGYGLGLAIAKSIVVQHQGKI
                     SAKSVPNGTTTFEVQLNER"
     gene            complement(2189..2866)
                     /locus_tag="SK3146_RS00405"
                     /old_locus_tag="SK3146_00078"
     CDS             complement(2189..2866)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1008: response
                     regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019914719.1"
                     /locus_tag="SK3146_RS00405"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SK3146_00078"
                     /product="response regulator transcription factor"
                     /protein_id="WP_249863197.1"
                     /transl_table=11
                     /translation="MRILIVEDEINLAEALSQILKKQHYSVDAVHDGQEGLDNALSGIY
                     DLLLLDIMLPGMDGMTILKTIRAQGIHTPVILLTAKGEIPDRIAGLDYGADDYVAKPFS
                     TDELLARIRAALRRKGEIVPEDGLRFEDLELNTSTLKLTCKGKELKLILKESELLELLM
                     TRKQSVTSKEQMIEKLWGFDSDAEHNNVEVYISFLRKKLAFLHSSVKISTIRGVGYVLE
                     VSS"
     gene            3099..3839
                     /locus_tag="SK3146_RS00410"
                     /old_locus_tag="SK3146_00079"
     CDS             3099..3839
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006038388.1"
                     /locus_tag="SK3146_RS00410"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SK3146_00079"
                     /product="polyphosphate polymerase domain-containing
                     protein"
                     /protein_id="WP_249863198.1"
                     /transl_table=11
                     /translation="MAIEVFNRYENKYLMDTEAFHRLYSSLMEYMEPDAYNKDDKFYSI
                     SNLYYDTEYHSLVRNSLSKPKYREKLRIRAYGVPAPDAKVYLELKKKVFGLVNKRRTAI
                     RLQEAYEFVRTGQPPAYREGMNRQVIREIGYFLSRYELQPMTYLAYDRIAMFCKGNRDL
                     RITFDTNIRTRRYDLSLECGDYGEQLLERGQWLMEVKAEKTIPVWLSKLLSAHQMYRTS
                     FSKYGNEYKKSIRYAEPVKEQVFL"
     gene            3836..4513
                     /locus_tag="SK3146_RS00415"
                     /old_locus_tag="SK3146_00080"
     CDS             3836..4513
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020617260.1"
                     /locus_tag="SK3146_RS00415"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SK3146_00080"
                     /product="DUF4956 domain-containing protein"
                     /protein_id="WP_249863199.1"
                     /transl_table=11
                     /translation="MIESIFNSSATVSQLTMSQALLTFAVAILLGGMISWTYMKTQTSP
                     SPSFTLTMTILPVIVAVIILLIGSNIARAFSLAGAFSIIRFRSAPGDSKDISYVLFSMA
                     SGLACGVGAYGYAALFTVLLCALMFILRAVKFGVSKESMKTLKVTIPESLGYEEAFDDI
                     FRKFNIDYELKKVRTTELGSLYEVIYAVKLGPNTDQKELLDAVRTRNGNLDITLTMNPA
                     LQE"
     gene            4536..6554
                     /locus_tag="SK3146_RS00420"
                     /old_locus_tag="SK3146_00081"
     CDS             4536..6554
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014368460.1"
                     /locus_tag="SK3146_RS00420"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SK3146_00081"
                     /product="carbohydrate-binding domain-containing protein"
                     /protein_id="WP_249863200.1"
                     /transl_table=11
                     /translation="MKRYSKTKRIAAALLALILVAGCSANTPDIAATTAASSSASAAVQ
                     SGGSASAAAVQLADASASESAGFDEDDALTSWSEDSSTAIALNGSGANVEGAGAKAEGN
                     VVTITEAGTYVAKGALDGQIVVNAPKDAVVHLVLNGAQIHNNDGPAVHVKAADKTIVTL
                     PEGTDNTLTDGAVYADTSDDAPTAALYSKGDLTINGGGKLSVQGNANDGITSKDDLKIM
                     GGTISVKAADDGLIGRDLFAVQDGSITIEAGGDGVKTTNDTGEDKGKVAIAGGTLNITS
                     ANDGIQSAASLIIDGGMFHIVSGGGSAASIKTHQDQNQGPRGFNRQAAEQSQSAAAAQT
                     QQNDSDSSSAKALKAAGDMAISGGEFEIDAADDAIHSNANIAILGGTYRLASGDDGIHA
                     DTSISISDGTIDISKSYEGIESMNIAISGGTIHLVASDDGLNGGGGSSGSDASKGGAGS
                     ANGMLTISGGYVYVDAEGDGLDSNGSIAMSGGTVIVNGPTRDGNGALDYDGTFDLSGGT
                     LIAAGSSGMAQAPSETSPQRSFLMTFPSTLEGGTLVTITDGSGAEVAAFAPAKAFSSIV
                     VSGANLKAGEEYTISTGGASSGTVQDGMYQGGTVSGSAKVVTFKLGDTVTYVNESGVTT
                     ANTGMGPGGGRGPGGAGGQGRPAGGGREAGQPGQPAK"
     gene            <6599..7099
                     /locus_tag="SK3146_RS00425"
                     /old_locus_tag="SK3146_00082"
                     /pseudo=""
     CDS             <6599..7099
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF015863.4"
                     /locus_tag="SK3146_RS00425"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /old_locus_tag="SK3146_00082"
                     /product="PepSY-associated TM helix domain-containing
                     protein"
                     /pseudo=""
                     /transl_table=11
                     /translation="WAMRKYRQLHLWIGLLTSVLILIEAVTGLLLSEPALMGQGQSSRT
                     EMRVPAQNSGAAAASLPSGVSADAAGAVQVQGGDNMKGAASSGGGQQGKPAGGFGQQGN
                     SFVGFIHGLHEGRVGSVNVKWLADVTAVGLIILTVTGISLSLQTLRAQRRSRIKRAAES
                     LHR"
     misc_feature    7127..7143
                     /note="TFBS match to ZuR_variant_2, Zinc-responsive
                     repressor, confidence: weak, score: 22.22"
                     /tool="antismash"
     gene            7187..7513
                     /locus_tag="SK3146_RS00430"
                     /old_locus_tag="SK3146_00083"
     CDS             7187..7513
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009672436.1"
                     /locus_tag="SK3146_RS00430"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SK3146_00083"
                     /product="antibiotic biosynthesis monooxygenase"
                     /protein_id="WP_249863202.1"
                     /transl_table=11
                     /translation="MLIQTRTIVVQKGSADLVVERFTKESPMDAMEGLIDKTVMVNRKK
                     QDETEEVVVMIRWRSVEDWKNWEKSDVHIQGHRQNHGKPKPEYVISTTVNMYEVKAVKE
                     GSGK"
     gene            7617..8531
                     /locus_tag="SK3146_RS00435"
                     /old_locus_tag="SK3146_00084"
     CDS             7617..8531
                     /EC_number="2.7.1.-"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_process="GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) APH"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF013775.4"
                     /locus_tag="SK3146_RS00435"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SK3146_00084"
                     /product="aminoglycoside phosphotransferase family protein"
                     /protein_id="WP_249863203.1"
                     /sec_met_domain="APH (E-value: 5.2e-24, bitscore: 84.1,
                     seeds: 156, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRKDKDRDIAADPVLSNEIVLGLVQKHVPEAREVRQVDETGNRAR
                     TYMIDEDIVLKTQRPSKIRPQTSLHKEVFFLLQLQADERIRVPRVLGYGTEDGVEYTVM
                     TRMPGVAARWLDLQGEERSRVMRDLGQMLRYIHQLDQAPFKESPFFQGSLRETDIKSSI
                     EQQLAAAVERLGDRPPGWTLTITVEQAAGQILDSLPSHAETVALHANPGPSHTFVYPES
                     KAFSGLIDFGDAYISHPAFDLVSWGSSEDQRHIFEGYTLEVPASGEFRAVWRAAAMLRL
                     LRSAGRNGAAAFHEDLTHWLSQR"
     gene            complement(8664..9746)
                     /locus_tag="SK3146_RS00440"
                     /old_locus_tag="SK3146_00085"
     CDS             complement(8664..9746)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0000910 - cytokinesis [Evidence IEA]"
                     /GO_process="GO:0007059 - chromosome segregation [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016362809.1"
                     /locus_tag="SK3146_RS00440"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SK3146_00085"
                     /product="ParB/RepB/Spo0J family partition protein"
                     /protein_id="WP_249863204.1"
                     /transl_table=11
                     /translation="MEIINIATDLIDEDKEQPRYQFAEESLQELMNSIEELGLLSPIKV
                     RALDGGRYKIIYGNRRYKACKALGRASIPCIVSAVTNELDIYLEQIAENLTREGFSPIE
                     EAEAFHKLMNDPKFSSSVKYLSSKLGKPESYIKNKCELLKFGNAVKKMIVGGTEIRKDA
                     LTEEQLLPIKDLPLEHRDPLAKIIARDELPVSDVKKIARLFKDKSISSSTKDKLLYKSG
                     PELIETWSVFEQNKAERTKPSQPKAAAAKKEKTEEAQNSELPATPPAAAATATAASIRS
                     SEIASASPSPLESKLRSLLTALPANTPLPADWTQLPPEAQERLLGDVHTLIDTLEKQLK
                     EWRQVKELYSSAPVAAGLQE"
     gene            10001..10798
                     /locus_tag="SK3146_RS00445"
                     /old_locus_tag="SK3146_00086"
     CDS             10001..10798
                     /GO_process="GO:0009058 - biosynthetic process [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: phytoene_synt"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: PT_phytoene_like"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009709568.1"
                     /locus_tag="SK3146_RS00445"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SK3146_00086"
                     /product="squalene/phytoene synthase family protein"
                     /protein_id="WP_249866131.1"
                     /sec_met_domain="PT_phytoene_like (E-value: 1.8e-23,
                     bitscore: 81.9, seeds: 61, tool: rule-based-clusters)"
                     /sec_met_domain="phytoene_synt (E-value: 3.1e-07, bitscore:
                     28.6, seeds: 8, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDMLASTSRTFYIPISRLVSGLKEAVASAYLCMRAIDEIEDHPEL
                     ASDLKVKLLLGVGRILRETEREAQLQALFAPYGDTLPEVTLRLNDWVAICPKSIADTVL
                     QSTAVMSEGMAEWVEKRWAIRTEEDLDRYTYCVAGAVGELLSDLWMWYDGTQTDRVKAV
                     AFGRGLQAVNILSNRMDDSTRGVSFFPEHWGMEEMIQYTRKNLQLADEYIADLKRGPVL
                     NFCSIPLALAHGTLKAITAGKSKLNRAAVLEIVSRVVTGKITL"
     gene            10962..11993
                     /locus_tag="SK3146_RS00450"
                     /old_locus_tag="SK3146_00087"
     CDS             10962..11993
                     /GO_process="GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1016: LuxR family
                     DNA-binding response regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019535054.1"
                     /locus_tag="SK3146_RS00450"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SK3146_00087"
                     /product="response regulator"
                     /protein_id="WP_249863205.1"
                     /transl_table=11
                     /translation="MIKWGESMYHVLVAEDEVWIRNAIVEMIERFDLGFKVVAQASDGM
                     EAWNLINQCWPNVVITDIVMPQLDGLSLLQKCDEYHISMVPIVISGYENFKYAQQAMRY
                     GATEYLLKPVPAEDLKRALTRSVERLQQFHSNHEPLHKIQHFIETMEMMNHQQLVKDAV
                     QLILYIGKMKADTRVKSGLYRIFANKLNDQLDSVIRNYRKLPLDNDKDAEAIQSYFVKL
                     LEEWSRHQHRDEQKNRALLKKVNEYVQKNYHKDITLSQIADYTDLSISRFCVLFKMNSG
                     DSFINYVNMFRIEKAKHLLLDTDLKVYEVADMVGFSSLPYFNRLFKSVANQTPNEYRRS
                     LGL"
     gene            11990..13774
                     /locus_tag="SK3146_RS00455"
                     /old_locus_tag="SK3146_00088"
     CDS             11990..13774
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010348118.1"
                     /locus_tag="SK3146_RS00455"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SK3146_00088"
                     /product="cache domain-containing protein"
                     /protein_id="WP_249863206.1"
                     /transl_table=11
                     /translation="MKLPRLQVNSIKHRMIILFLALSLLSIGLITLFSHYYYSKAVKED
                     FKLITTEATNRLNHHMEFYFKQMKNSTNTLINTALTQQWLRQEYVPGPEDINEIEMEMK
                     TYVSFNFPEIVNMYLVSNDKRVLPLFNNKSRNQTYANESWYSAVPLTAVTVLPTQRLDG
                     TGPLVLSMVIPIYSTINLEIIGNLVVQFSLSEIEATFAKSKLGKTGFFFILSGDNTFVY
                     HPNKEWIGKRITDTPLKELDWEGAAEKNMYDVNGTAYLVSYGVSSDTGWKIVSIVPYAE
                     MAHSLQSAVQSTLITFVVISLLIMIVIPLLLRQFIHPIKQLKSLMEAVAMGNLSVRAHK
                     VSTINEFQILNYSFNKMVKQLIILMDEVSYYKVKEVELQLKQSEATIRALQNQINPHLL
                     YNTLDIIKSIAFLEDVPLIEKITQNLADVYRYASKWSYDEVTLEEELSSLTKYLDIIHI
                     RYPKKFESGVRVNEKLLSCPIIKLSIQPVVENAVKYAVEPKGGEAAIIVTAYKERQDLI
                     IEIADNGPGISDEKLASLEEQFASQSSNEETLMSGTIGLANVHARLSLKYGQGYGVFVH
                     SFPGRGSVISIRIPYRGP"
     misc_feature    complement(13844..13858)
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence:
                     medium, score: 21.68"
                     /tool="antismash"
     gene            13947..15302
                     /locus_tag="SK3146_RS00460"
                     /old_locus_tag="SK3146_00089"
     CDS             13947..15302
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005808317.1"
                     /locus_tag="SK3146_RS00460"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SK3146_00089"
                     /product="transposase"
                     /protein_id="WP_249866132.1"
                     /transl_table=11
                     /translation="MLHHNSQSEKGEERFSALFSTLKVGHFLRQAGIRKSFGFPAFTVF
                     QLIFTLIFQQRSWSRLLQSNRSSLPGKDVVYRFLNHPGFAWRRFFHSFSLKIIEHFESL
                     TSSSRVRAFIVDDSVLKRNRCKKAELLARVHDHTTGRFVRGYNMLTLGWSDGFSFAPID
                     FVMLSSAKIANRFCEMKESLSKRTQGYKRRLEAFSRKPDAVVAMLDRAIQAGFAADFVL
                     MDSWFTQAPLLRSLMAKGLHVIGMIKDMKQRYRLDDKRMTLKELYVKLSRSSKTEILGS
                     VLTRTDCGLPIKLVFVQNRNCRREWLAILSTDIELADAEIVRIYGIRWSIETFFKFTKS
                     YLKLGTEFQGRSFDMLISHTTLVFTRYLVMEWERREHQDQRSLGGLFFLFSDEVRDLDL
                     KAALQQIVSFFIELTQTKTKQGKSAILSQVQQWISGLPSYIKALMPNLSCET"
     gene            15384..16880
                     /locus_tag="SK3146_RS00465"
                     /old_locus_tag="SK3146_00090"
     CDS             15384..16880
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1143: sugar-binding lipoprotein"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019535056.1"
                     /locus_tag="SK3146_RS00465"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SK3146_00090"
                     /product="extracellular solute-binding protein"
                     /protein_id="WP_249863207.1"
                     /transl_table=11
                     /translation="MKTWTPLLLAGALAAGAAGCSQGNSASGDAPSGSKEPLTINMMTT
                     SYAGGGWPEDHPIIKEIDKKLNINLKVQWVPSDTYSQKLNVMAASNDFPDVFYVPEAEF
                     NKWRDKGVFMDVKPELGNYANLTKYIPADAMAKMNPKDKYYGFPYYVTDTRDTLAIRKD
                     WLDKLGLKMPTTTDEFYEVAKAFATKDPDGNGQADTPGFSFGIVNNKFSQIEPIMGAFG
                     LGNDWAEINGQLVPMQVQTEELKQFAAFMQKAYAEGVMDKDFPANKLKDSVAKLEAGKT
                     GIAMIVTNEFFNGTLPTLKKLTPSAELVQLLPPKGPSGKQTSQTLQMTNKIVINAKIDA
                     AKKQRILQMLDYMLSDEGYDLIKNGIEGVHYTKSGDGKFQKLEAFDKDRPQLLSTWFFR
                     RFDPGIQIRKWDDQEVAQKIKTIIDANEKFRWTNPAEGFFSETMTKKGANLQQKWMETM
                     TKVIVGQAPLAAIDDAAAAWKRDGGDEIIKEINAQYQTLK"
     gene            16932..17849
                     /locus_tag="SK3146_RS00470"
                     /old_locus_tag="SK3146_00091"
     CDS             16932..17849
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1067: putative ABC
                     transporter permease protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019532977.1"
                     /locus_tag="SK3146_RS00470"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SK3146_00091"
                     /product="ABC transporter permease subunit"
                     /protein_id="WP_249863208.1"
                     /transl_table=11
                     /translation="MNEGVIDMQKAVKQGIPLYIMILPDLLYFLLFRYAPMGGIILAFK
                     DFDPFEGIWASPWVGFKHFQVLFSEPDFWRLLTNTLMLSALNLFLYFPVPIVIAVLLNE
                     ARIKWFAKTVQTVVYIPHFVSWVVVVGITVVLFASQDGGVNKLLAEYGWSRIDLLTDPG
                     YFRALYVLQSIWKETGWGTIIFLAALASIDPTLYEAAVMDGAGRWRQMWHITLPALRTI
                     AVLLFILRLGQVMDSGFEHIYLLQNSLNLAVSDVFDTYVYRQGVLQGEYSFTTAIGLFK
                     SIVGLIFVLAANKLAKRFGEEGVY"
     gene            17851..18720
                     /locus_tag="SK3146_RS00475"
                     /old_locus_tag="SK3146_00092"
     CDS             17851..18720
                     /GO_process="GO:0008643 - carbohydrate transport [Evidence
                     IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1069: putative ABC
                     transporter permease protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007131283.1"
                     /locus_tag="SK3146_RS00475"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SK3146_00092"
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="WP_249863209.1"
                     /transl_table=11
                     /translation="MNKLVAGKRDILFNLLIYGLLAFSLLVVLLPFLYVLFSSFSTKAE
                     YLSRGFYLFPREWTFNSYGYLTNNKGFLSSYANTLYITAVGTAINVFVTCLMAYGLSKS
                     WLRGRSWLNFMVLFTMIFNGGMIPTYLVLKELSLINTYWALFLSGAVAPFVLIIMRSFF
                     STIPAELEESARIDGCSEWRLLFSIVIPLSLPSIVTVTLLYGVAHWNAYFQAILYLNDS
                     AKWPVQVFLRQLLLETDSSMELNIGDYEYGPPVRMAAVIATALPLLLCYPFLQKYFNKG
                     MFVGSVKG"
     gene            18749..20233
                     /locus_tag="SK3146_RS00480"
                     /old_locus_tag="SK3146_00093"
     CDS             18749..20233
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019532915.1"
                     /locus_tag="SK3146_RS00480"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SK3146_00093"
                     /product="sulfatase"
                     /protein_id="WP_249863210.1"
                     /transl_table=11
                     /translation="MKAIVILMDTLNRQLLEMYDPASWVRTPNLSRLAEKCAVFDQHWS
                     GSLPCMPARRDMFTGRLGFLERGWGGLEPFDVTLPQVLKRHRIFSHIVTDHYHYFKTGG
                     ENYCQAFSSWDLHRGQESDPWVSRVRDPASLQEPHYGRVEPQYEKNRAAFRREEDYPGP
                     RTMSAACCWLEDNKEAESFFLMVEAFDPHEPFDCPQHYLAMYGDDYTGPRMEWPKYSRV
                     SEPPEAIEHLRKRYAANLTMIDHWLGKLLDTMDHNGLWDDTLLIMTTDHGFLLGEHDWT
                     GKNIMHVYNEIAHLPLMVHVPGTAVAGTRISAITQNIDIMPTILDYFGIDIPPSTRGKS
                     WLPLLDGTAQKLRDCALYGMFGMTVNITDGAYTYLRAPVREDNVPCYAYTAMPTTFGSF
                     LGASVPEQIETGRFLSYTAFPVYRIPVSQAGVPFKMAQHGQRSLLYSMEADYRQAAPVE
                     DEGLIRSYTELLIRAMELEQAPEEQYERLGLKPGNR"
     misc_feature    complement(20357..20371)
                     /note="TFBS match to VqsM, Regulator of quorum-sensing
                     signalling systems, confidence: medium, score: 17.56"
                     /tool="antismash"
     misc_feature    complement(20367..20384)
                     /note="TFBS match to HipB, Bacterial antitoxin HipB,
                     confidence: weak, score: 22.53"
                     /tool="antismash"
ORIGIN
        1 gtagcggacg ccgtcaatca aatgttcgtc ttcgccggaa gcgtgcttgc agagaaaaag
       61 ccgacgaagc gattcccggc cggtttcggc cgcgtcatca atttgttctg tatggtcgct
      121 gtaatcgtcg tcacgattat ggcgtacgag acgatcaagg aaggaattca tctgatccag
      181 catcctatcc attcatccgg cttctggctc aatataatcg tattggcggt ttctattctt
      241 atagacggct tcgtgcttgt caaagcgatg aaagaagtcg tccgcgaatc ccgcagcgat
      301 gcgaaagggt tggcagtcgt atccgccgcg ttccgcaatg tgaagcgggc ggcgcctccg
      361 acacgtcttg tcttctatga agatctggtg gcaaccatag gcggtttgct tgctcttctc
      421 gccgttatcg tcacctcgct tagcagcttt gccgtcttgg acggcgtcgt cacggttgcg
      481 atcggctgct tgatggtgct aatcgccttt cgcgtaggct atgacaatat ggcgggtctg
      541 atcggcgtag ctgctcctct cgaagtagag gagagggtcg cgggtatcat attagccgaa
      601 agcttcgtga ccgacatcta ccagctgagg gtgcttcagg aaggacgcta ttatcacgtg
      661 gaaggcttga tcgagctgca gcgcggctta acgctggccg atgcggacga tatcaaattt
      721 aaagtgagag accaactgct tcaggacccg gatattaccg atgtcacttt gggaatactg
      781 gaagacaacg gggtaagaaa ctgggttccg gccgaaagca gctaatataa taaggcatgg
      841 ccaaaaaaaa acgtttcagg cttatcgctt gaaacggttt ttcgttgttg ccgctgcttg
      901 ctgccgccgc cgatgtgtga aaaagcaaga agctagcgct cgttcagctg aacttcaaac
      961 gtcgtcgtcc cgttcggaac gctttttgcg gaaattttgc cttgatgctg cacgacaatg
     1021 gatttcgcaa tggcaagccc taagccatag ccgccgtttt gccgcgagcg cgaaggatcg
     1081 gcccggtaga aacggtcgaa aattttatcc agatgctccg ccggtatgcc cggtcctgta
     1141 ttgcttaccg tcaatcgtac atggttttga tgctttttca acgcaagaac gatagagccc
     1201 ttaggattgg aatatttaat ggcgttgtcc agcaggatca tcgccacttg tttcatctgt
     1261 tcgctgctgc cggtgacggt tagctcaggc tcaatgtcgt aatccagcgc aagatccttc
     1321 tcgaatatga cggcctccat ggtcagaatg acactctcta cggcttcgct cagatcgaag
     1381 gggacgtaaa gcatccgcgg cttggcgtca tccatttcgg tgagatagag caaatccctc
     1441 gtcaaagtct tcatgcgctc cgtctccgcc ttaatatgat gcagccattt ggcctgcccg
     1501 ttgacggtgt cctcgccatt ggccagtaga acgtcggcat tagtattaat gacggccaga
     1561 ggcgtcctca gctcgtgaga agcgtcggcg ataaaacgct tttgcttctc aaaggcttct
     1621 ttgaccggct cgatagaccg gtcggcgaaa tagcggctgg tcaaataaat gatccccagc
     1681 atgaaaagcg cgacggcgga gaaggtgtac acgagattgg ttagaatcgt ttgccggtcg
     1741 gtgacgtcca tatatacgat gaaatacccc gattgattat tgatgacact gtaggcccag
     1801 cgggttccgt tgagggtgaa ctggctgatt ttttcgggat gctcggcagc cttcttcacc
     1861 gcggcggcat aaaagtcgct gctcatatcg aaccgcgagt tcgtttcggt tatactccat
     1921 tgcttgtcgg tttgcagcga gaaggagacg gaacgcatat gatcctcccc cggcatatcc
     1981 ccgcccctcg gtcctgcggg tccgcctttt ttgcctatgg gtccgtcctt tttattcgac
     2041 gcatccgccg tgtgctgaag atccatcata atatctttgc gcacgttttg atacgtaatc
     2101 gtatagatga tggtgaaagc gccgagcatg atgatcgaaa tgatgaccat attcatcaaa
     2161 agaagccggt tgcgcagttt gtcgaacatc aggaggatac ctccagtacg tagccgacgc
     2221 cccgaatcgt gctgatcttg accgaggaat gcaggaaagc cagcttcttt cttagaaacg
     2281 aaatgtacac ttctacgtta ttgtgctcgg cgtccgagtc aaatccccac agcttctcga
     2341 tcatttgctc cttggaagtt accgattgct ttctcgtcat caagagctcg agcaattcgc
     2401 tttctttcag aatcagcttc agttccttgc ctttgcacgt aagcttcagc gttgaggtat
     2461 tcagctcaag atcttcgaat cgcagcccgt cctcgggcac gatctctccc ttgcgtctga
     2521 gcgccgccct aatgcgcgcc agaagctcat cggtagagaa gggcttggct acataatcgt
     2581 ctgcgccgta gtcgagcccc gcgattcggt ccggaatctc ccctttggcc gtaagcagaa
     2641 tgaccggcgt gtggatgcct tgcgcgcgaa tcgtcttcaa gatcgtcatt ccgtccatgc
     2701 cgggaagcat gatatccagc agaagcaggt catagatgcc gctcagcgcg ttatccaatc
     2761 cctcctggcc gtcatgaacg gcgtcgacgg aatagtgctg cttcttcaaa atttgcgaga
     2821 gcgcctccgc caaattgatc tcgtcctcca caattaatat tctcatggct gcaactccct
     2881 tcgcgtcttt atatttctat tatggcagga gaacctttaa tcaaccttaa gccgctcccg
     2941 gttcggttcg tctgcttcgg ttataacata aaaccccatg cggtttccaa aaaattttcg
     3001 gctcgtgaag gaatttaaga ttcgttaaag gttcgcctcc taagatacag acatgcgaaa
     3061 tacgagacag tcgctaacag agaaaggagc gttgaacgat ggcgatcgaa gtgttcaacc
     3121 gatacgagaa caaatacttg atggataccg aagcgtttca ccggctctac agcagcctga
     3181 tggaatatat ggagccggat gcgtacaaca aggacgacaa gttttattcc atcagcaatc
     3241 tgtactacga taccgagtac cacagcttgg tgcgcaacag tctctcgaag ccgaagtaca
     3301 gagagaagct gcggatcaga gcttacggcg tccccgctcc ggatgccaaa gtctatctgg
     3361 agctgaagaa aaaggtgttc ggtcttgtca acaagcggcg caccgcgatc cggcttcagg
     3421 aagcatacga atttgtccgg accgggcagc caccggcata ccgggaagga atgaaccggc
     3481 aagtgatccg ggagatcgga tacttcctgt caagatacga gctgcagccg atgacgtatt
     3541 tggcgtacga ccggatcgcg atgttttgca aggggaaccg ggatttgagg atcacgttcg
     3601 acacgaacat ccggacgagg cgttacgatt tgtcgctgga gtgcggcgat tacggcgagc
     3661 agctgctgga gcgcggccag tggctgatgg aagtgaaggc ggagaagacg attccggttt
     3721 ggttgtccaa gctgctgtcg gctcatcaga tgtatcgaac gagcttctcc aagtatggca
     3781 acgagtataa aaaatcgatc cgttacgcgg aaccagtaaa ggagcaggtg tttctatgat
     3841 cgagtctatc ttcaattcaa gcgcaaccgt ctcgcaatta acgatgtccc aggcgttgct
     3901 taccttcgcg gtcgctatcc ttctcggcgg tatgatcagc tggacctata tgaagacgca
     3961 aacctcgcct tcgccgagct tcacgctcac gatgacgatt ttaccggtaa ttgtcgccgt
     4021 tattattttg ctgatcggca gcaatattgc gcgcgccttc agtcttgccg gcgccttctc
     4081 gatcatccgg ttccgcagcg cccccggcga ttcgaaggat atctcatacg tcctgttctc
     4141 gatggcgtcg ggccttgcct gcggcgtcgg ggcttacggc tacgcagcgc tgttcaccgt
     4201 gctcttgtgc gcattgatgt ttattctaag agccgtcaag ttcggcgtca gcaaggagtc
     4261 tatgaagacg ctgaaggtca ctatcccgga gagtctcggt tacgaggaag cgttcgacga
     4321 catttttcgg aagtttaaca tcgattacga attgaaaaaa gtacggacca ccgagctcgg
     4381 cagcctgtac gaagtcattt atgccgtgaa gctcggcccg aatacggatc agaaggaact
     4441 gctcgacgcc gtccgtacgc ggaacggcaa tctcgatatt acgctgacta tgaatcctgc
     4501 tttgcaggaa taacccaaag aggagctgat tgcttatgaa acgttacagt aaaaccaaaa
     4561 ggatcgccgc cgcattgctg gctcttatcc ttgtcgcagg atgcagcgca aatacacccg
     4621 atatagccgc cacaaccgcc gcttcgtctt ccgcctccgc cgcggttcag tccggcggct
     4681 ccgcttcggc ggccgccgta cagctggcgg atgcgagcgc ttcggagtcg gcgggcttcg
     4741 acgaagacga cgcgctgaca agctggagcg aggacagctc gaccgcgatt gcgttgaacg
     4801 gctccggcgc aaacgtagaa ggggcgggag ctaaggccga agggaatgtc gtaaccatta
     4861 cggaggccgg cacttatgta gcgaagggcg cgctcgacgg ccagattgtc gttaatgcgc
     4921 cgaaggatgc ggtcgtgcac ctggtgctga acggagccca gattcataac aatgacggcc
     4981 cggccgttca tgtgaaagcg gcggataaaa cgatcgtcac attgccggaa ggcacggaca
     5041 atacgttaac ggacggcgcg gtttacgcgg atacgtcgga cgacgcgccg acggcggcgc
     5101 tgtatagcaa aggcgatctg acaatcaacg gcggcggcaa gctgtccgtt caaggcaatg
     5161 ccaacgacgg catcaccagc aaggacgatt tgaaaattat gggcggcacg atcagcgtga
     5221 aagccgcgga cgacggcctg atcggccgcg atctgttcgc cgtacaagac ggctcgatca
     5281 cgattgaagc gggcggtgac ggcgtaaaga cgacgaatga taccggtgag gacaaaggga
     5341 aagtcgccat tgccggaggg acgttgaaca ttacttccgc gaacgacggc attcagtcgg
     5401 cggcttccct gattatcgac ggtggaatgt tccatatcgt ctcaggcggc ggcagcgcag
     5461 cctccatcaa gacgcatcag gatcaaaacc aaggtccgcg aggcttcaac aggcaagcgg
     5521 cggagcagag ccagagcgcg gccgcggcgc agacgcagca gaacgatagc gattcctcca
     5581 gcgccaaagc gttaaaggct gcaggcgata tggcgatctc gggcggagag ttcgagatcg
     5641 atgcggcgga cgacgccatt cacagcaatg ccaatatcgc tatcctcgga gggacgtaca
     5701 ggctggcatc cggagacgat ggaatccacg ccgacacctc catctccatc tcggacggga
     5761 cgatcgatat cagcaagagc tacgagggga ttgaaagtat gaatatcgcg atttcgggag
     5821 gcacgattca tcttgtcgcc agcgacgacg gcttgaacgg cggcggcggc agcagcggca
     5881 gcgacgcgtc caaaggaggg gccggctccg cgaacggtat gctgacgatc agcggcggct
     5941 atgtgtatgt cgatgcggaa ggcgacgggc tcgactccaa cggctcgata gcgatgtccg
     6001 gcggcaccgt cattgtgaac ggcccgacac gcgacggcaa cggagcattg gattacgacg
     6061 gcaccttcga tctgtcgggc ggcacactca tcgccgccgg aagctcgggc atggcccaag
     6121 cgccgtccga gacttcgccg cagcgctcct tcctgatgac cttcccgagt actttggaag
     6181 gcggcacact ggtgacgatc acggacggat cgggggcgga ggtcgcagca ttcgcgccgg
     6241 cgaaagcttt cagcagcatc gtcgtatccg gggcgaattt gaaagccgga gaagagtata
     6301 ctatctccac cggcggcgcg tcctccggca cggtgcaaga cggcatgtac cagggaggaa
     6361 cggttagcgg aagcgccaag gtcgtcacct tcaagctggg cgacacagtt acttatgtca
     6421 acgaatcggg tgttactacc gcgaataccg gcatgggtcc cggcggaggt cgagggccgg
     6481 gaggcgcagg cggccaagga cgcccggcgg gaggcggcag agaggctgga cagcctggac
     6541 agcctgccaa atgattggaa ttcttaaaat atagagcgcc tgcgctcgca aggagaaatg
     6601 ggctatgaga aaatatcgcc agcttcattt atggatcgga ttgcttacct ctgtacttat
     6661 tttgatcgaa gccgtaaccg gcttgcttct gtcggaaccg gcgcttatgg ggcagggaca
     6721 atcgtcccgc acggaaatga gagtgcctgc gcaaaactcc ggcgccgcgg cagcatccct
     6781 cccaagcggc gtctccgccg acgctgcggg tgcggttcag gttcaaggag gagacaatat
     6841 gaaaggggcc gcgtccagcg gcggcggaca gcaagggaag cccgcgggcg gtttcgggca
     6901 gcagggaaat tcattcgtcg gattcattca cggtctgcat gaaggacgag tcggatctgt
     6961 caatgtcaaa tggcttgccg acgttacggc cgtcggatta attatattaa ccgtcaccgg
     7021 catttcgctg tcgcttcaga cgttaagagc gcaaagaaga agcaggatta aaagagcggc
     7081 tgaaagcctc catcgataaa atgtcatatt gaccaaatac gatatatcgt tataaaatag
     7141 cgatatatcg tattattttt ttcatacact aagaggaggt cttcctatgt taattcaaac
     7201 cagaacgatc gttgtgcaaa aaggtagcgc agatttggtc gttgaacgct ttaccaaaga
     7261 aagtccgatg gatgctatgg agggattgat cgacaaaacc gtcatggtca accgtaaaaa
     7321 gcaggacgag acggaagaag tcgtcgtaat gattcgctgg agatcggtag aggactggaa
     7381 aaattgggag aagagcgacg ttcatattca agggcaccgg caaaaccacg gcaaaccgaa
     7441 gccggagtac gtgatcagca ccaccgtgaa tatgtacgaa gtgaaggcgg taaaagaagg
     7501 ctcgggcaag taagtctccg cccctctgca tacttcggct gccgtaacgg ctgccggcgg
     7561 gcgttacgca aaataacgca cttgaaggaa taatccgtca taagggagga agagcgatgc
     7621 gcaaggataa ggatagagat attgcggcag acccggtgct cagtaacgag atcgttctcg
     7681 gcttggtgca gaaacacgtt ccggaggccc gggaagtcag acaggttgat gaaacgggaa
     7741 atcgagcccg cacttatatg atcgatgagg acattgtgct aaaaacgcag cgcccgtcca
     7801 aaatacgtcc tcaaaccagc ttacataaag aggtcttctt tcttcttcag ctgcaggcgg
     7861 atgaacggat acgggttccc cgggtactgg gctacggaac ggaggacggc gtcgaataca
     7921 ccgttatgac gcgaatgccg ggggtcgcgg cgcgctggct tgatctccaa ggcgaggaac
     7981 ggagccgggt gatgcgcgat ttgggacaaa tgctgcggta tattcatcag ctggaccaag
     8041 caccgtttaa agaaagcccg ttctttcagg gaagtcttcg cgaaaccgat atcaagagct
     8101 cgattgagca gcagctcgcc gccgcggtgg agcgtttggg ggacagaccg cccggctgga
     8161 cgctgacgat cacggtggag caagcggccg gtcaaattct cgattctctc ccgtcccatg
     8221 cggagacggt tgcgcttcac gccaatccgg gaccgtcgca tacgtttgtt tatccggaaa
     8281 gtaaagcgtt ctccggattg atcgattttg gcgacgccta catcagccat cccgcatttg
     8341 atttggtatc gtggggttcg agcgaagatc aacggcatat ttttgaaggg tatactttgg
     8401 aagtgcctgc aagcggcgag ttccgggccg tgtggcgagc tgcggcaatg cttcgcctgc
     8461 tgcggtcggc cggtcggaat ggagcggcgg catttcatga agacttgacg cattggctga
     8521 gccaacgtta aggggttcat tcatccggct tggacaacaa aggggtttct gcaagtccta
     8581 agaagacttg acagataccc cttcttctcc gtgataaaac cccggcatcg aagctttgcg
     8641 gcggaagacg gccgctctaa gctttactcc tgcagtccgg cggcgaccgg agcggaggag
     8701 taaagctcct tgacttgcct ccattccttg agctgcttct ccagcgtgtc gatcagcgtg
     8761 tgcacatcgc ccaatagccg ctcctgcgcc tccggaggaa gctgtgtcca atccgcagga
     8821 agcggggtgt tggccggcaa ggcggtcagc aaggaccgca gcttgctttc gagaggagac
     8881 ggagaagccg aagctatctc ggacgatctg atcgaagcgg cggttgcagt cgctgcagcc
     8941 gccgggggcg ttgccggcag ctcggagttc tgtgcctctt ccgttttctc cttcttggcc
     9001 gcggcagctt tcggctgaga cggcttggtc cgctcggctt tattctgctc gaagaccgac
     9061 cacgtttcga tcagctccgg tcccgattta tacagcagct tatccttcgt gctggaggag
     9121 atgctcttgt ccttgaaaag gcgggcgatt ttcttgacgt cgctgacggg aagctcgtcg
     9181 cgggcgataa ttttggcgag cggatcgcga tgctccagcg gcaaatcctt gatcggcagc
     9241 agctgctcct cggttagagc atccttgcgg atttccgtac cgcctacgat catttttttc
     9301 acggcattgc cgaatttgag cagttcgcat ttattcttga tataagactc gggtttgccg
     9361 agcttgctgg acaaatattt gacagagcta ctgaatttcg ggtcgttcat cagcttgtgg
     9421 aacgcctcgg cttcttcaat cggagagaag ccttcccgcg tcaaattttc cgcaatttgc
     9481 tccaaataaa tatccagctc gttggtaacg gcggatacga tacacgggat ggaggcgcgg
     9541 cccagagctt tgcaggcttt gtagcggcga ttgccgtaaa tgattttgta ccgcccgccg
     9601 tcgagcgccc tgacttttat cggggacagc agacccagct cctcgatgct attcattaat
     9661 tcctgcagcg attcttcggc aaactgatat ctgggctgtt ccttatcttc atcgatcaaa
     9721 tccgttgcaa tattaataat ttccatatgt attctcctat ccttgattct tggctccacg
     9781 cttccggcgg aggaagtata agtttattat ataacacgat cgcatcggtg gaaatgattg
     9841 cttcccgcaa gggcccgcag cagaaaataa aaatgaccgt atatttgcct ccataaagaa
     9901 gaaaagctat gatataaaga ggtcatagtt gctatcttac gacatttaac attatcggag
     9961 gtcatcggtg aacaggacga aagatttaac gaaggattcc atggatatgt tggcatcaac
    10021 tagcagaacg ttttatattc cgatcagccg cttggtttcc ggtttgaagg aggccgtcgc
    10081 ttcggcttat ttatgtatgc gggcgatcga tgaaatagaa gaccatccgg agctggcgtc
    10141 cgatcttaag gtgaagctgc tgctcggcgt cggccgcatc ctgcgggaga ctgaacgcga
    10201 agcgcaattg caagcgcttt ttgctccgta cggggacacg ctgcctgagg ttacgctgcg
    10261 gttgaacgat tgggttgcga tctgccccaa atcgattgcg gacaccgttc tgcaaagtac
    10321 ggccgtcatg tccgaaggca tggccgaatg ggtcgagaaa cgatgggcga tccggacgga
    10381 agaggatttg gaccgctata cgtattgcgt ggcgggagcg gtaggggaat tgctttccga
    10441 tctgtggatg tggtacgacg gaacgcaaac cgatcgcgtc aaagccgtag cgtttggccg
    10501 cgggcttcaa gccgtcaata ttttaagcaa tcggatggac gattccacaa ggggagtcag
    10561 cttcttcccg gagcattggg gcatggaaga gatgattcaa tatacgcgca aaaatttgca
    10621 gttggccgac gaatatatcg ccgacctgaa gcgcggcccc gtgctgaact tctgcagcat
    10681 tccgctggcg ctggcgcacg gcacgctgaa ggcgatcacc gccggcaaaa gcaagctgaa
    10741 ccgggcggcc gttctggaaa tcgtaagccg ggtggtaacc ggcaaaatca cgctgtaacg
    10801 ctaaagcgaa gcgcccttcc tgaaaagacg taccgatccg gcaagatgcc gatgacggaa
    10861 gtctcgcggg agggcgctgt tttgtcgtct tccgttatgg aagccgaatg aaaaatccgg
    10921 ttcaaatcgg acggacgata tgatagactt caccttatcg aatgattaaa tggggtgaat
    10981 ccatgtacca tgtgctggta gcggaagacg aagtttggat tcggaacgcg attgtggaga
    11041 tgatcgagcg tttcgatctc ggctttaagg tggtagctca agcgagcgac ggtatggagg
    11101 cttggaactt gattaaccag tgttggccta acgttgtcat tacggacatc gtgatgccgc
    11161 aactggacgg gctgtcgctg ctgcaaaaat gcgacgaata tcatatatcc atggttccga
    11221 tcgtgatcag cggctatgaa aatttcaaat atgcccagca agcgatgcga tacggcgcga
    11281 cggaatattt actgaagccg gtgccggccg aggacttgaa acgggcgttg acgcgttccg
    11341 tggaacggct gcagcagttt cattccaacc atgagccgct gcataaaatt cagcatttta
    11401 ttgaaacgat ggaaatgatg aaccatcagc agctggtgaa ggatgcggtg cagctcatct
    11461 tatatatcgg aaaaatgaaa gcggatacaa gagtgaagtc ggggctgtac cgcatttttg
    11521 ccaacaaatt gaacgatcag ctcgacagcg tcatccgtaa ttaccggaaa ttgccgctgg
    11581 acaacgataa ggacgcagag gcgatccaaa gctactttgt aaagctgctg gaagagtggt
    11641 cgcgccatca gcaccgggat gagcagaaaa accgcgcgct gctgaaaaaa gtcaacgaat
    11701 acgtgcagaa aaattatcat aaggacatta cgctatcgca aattgccgac tataccgatc
    11761 tgagtatttc cagattttgt gtgctgttta aaatgaacag cggcgattcc ttcatcaatt
    11821 atgtaaatat gttccgcatc gagaaggcca agcatttact gctggatacg gatcttaaag
    11881 tatacgaagt cgcggatatg gtcggcttct cgtcgctgcc gtatttcaac cgcctcttca
    11941 aaagcgtcgc gaatcaaacg ccgaacgaat acagaaggag cttagggcta tgaagcttcc
    12001 acggctgcag gtcaattcca tcaagcacag aatgattatt ttatttttgg cgctaagctt
    12061 attgtctatc ggattaatta ccttattttc ccattattac tacagcaagg cggtcaagga
    12121 agatttcaag ctgattacga ccgaagcgac gaaccggttg aaccatcata tggagtttta
    12181 ttttaaacaa atgaaaaatt cgacgaatac gctgatcaac accgctttga ctcagcaatg
    12241 gctcaggcag gaatacgtcc ccgggccgga ggacatcaat gaaattgaaa tggagatgaa
    12301 gacgtacgtc tccttcaact tcccggaaat cgtcaacatg tatttggtgt ccaacgacaa
    12361 acgggttctt cctttgttta acaataaaag ccgtaaccag acgtatgcca acgagtcatg
    12421 gtattcggcc gtgccgttga ccgcggtcac cgtgctgcct acgcagcggc tggacggtac
    12481 cgggcctctc gtattaagca tggtcattcc catctacagt acgatcaatc tagagataat
    12541 aggcaacctg gtcgttcagt tctcgctgtc ggagattgaa gcgaccttcg ccaagtcgaa
    12601 gctcggcaag acgggcttct tctttatcct ctccggcgat aacacgttcg tctatcatcc
    12661 gaacaaagag tggatcggca agcggatcac ggatacgccc cttaaggagc tggattggga
    12721 gggggccgca gagaaaaata tgtacgatgt gaacggcacc gcgtatctgg tctcttacgg
    12781 cgtatcaagc gatacgggct ggaagatcgt ttcgatcgtg ccgtatgcgg agatggccca
    12841 cagcctgcaa tcggccgttc aatcgacgct gattacgttc gtcgtcatct cgcttctcat
    12901 tatgatcgtc attcctctgc tgctgcgcca atttattcat ccgatcaagc agctcaagtc
    12961 gctgatggag gcggtggcga tggggaactt gagcgtcaga gcgcataaag tgtcgaccat
    13021 taacgaattt caaatcttga attacagctt caataaaatg gtcaagcagc tgatcatctt
    13081 aatggatgaa gtatcgtatt acaaggtcaa ggaagtggag ctgcaattga agcagagcga
    13141 agcgacgata cgcgcgctgc aaaaccagat taatccgcat ttgctctaca acacgctgga
    13201 tattattaaa agcatcgctt ttctggagga cgtccctctg atcgagaaaa tcacccaaaa
    13261 tttggccgac gtctaccgct atgcgtcgaa atggtcttac gacgaagtaa cgctggagga
    13321 agaactaagc tcgttgacca aatatttgga catcattcat atccgttatc cgaagaaatt
    13381 cgagagcggc gtccgcgtca acgaaaagct gctgagctgc ccgatcatca agctgagcat
    13441 tcaacccgtc gtcgaaaatg cggtcaaata cgcggtcgaa ccgaagggag gcgaagcggc
    13501 gatcatcgta acggcgtata aggagcggca agatttaatt atcgagattg ccgacaacgg
    13561 ccccggcata tcggacgaga agctggcaag tctggaagag caattcgcca gccaatcgtc
    13621 gaatgaagaa acgctgatga gcgggacgat cggcctggcc aacgtacatg cgcgcttatc
    13681 gctgaaatac gggcaaggct acggcgtctt cgtgcatagt ttccccggac gcggcagcgt
    13741 catcagcatc cgcattccgt atcgcggccc gtaaaaaaat ccgattataa ataactcaag
    13801 tttcgcacct tgaaaaacac gcttagatac tgctgctact gaaaatcttt tgaaaaatta
    13861 gcaagcttga cagaaaaaca cccttcatgt ttggtaaaat ggaaattgtc cagataacca
    13921 ttccaaaccg aagggtgcgt aaccttatgt tacaccacaa ctcccagtct gaaaagggtg
    13981 aagaacgttt ttctgccctg ttttccactt tgaaagtagg acactttctc cgtcaagctg
    14041 gcattcgtaa atcgtttggc tttccggctt ttactgtctt ccagcttatc tttacgttaa
    14101 ttttccagca acgaagttgg tcccgtttac tccaaagcaa ccgttcttca ctgccgggta
    14161 aagatgttgt ctatcgtttt ttgaatcatc ccggttttgc ttggagacgg ttctttcata
    14221 gctttagcct gaaaatcatt gaacactttg aatcccttac ttcctcttca cgagttcgtg
    14281 cgttcatcgt tgacgactcc gtcctgaagc ggaatcgttg taaaaaggct gaactgttgg
    14341 cacgggttca tgaccacacg acaggtcgtt tcgtacgcgg gtacaacatg ctgactctcg
    14401 gctggtcgga tggttttagt tttgctccca tcgattttgt catgctcagt tcagctaaaa
    14461 tagccaaccg tttctgcgaa atgaaggaat cgttgtccaa acgtacgcaa ggctacaagc
    14521 ggcgtcttga ggcgttttct cgcaagcccg atgcggtcgt agctatgctg gaccgtgcga
    14581 ttcaggctgg ctttgcagcc gatttcgtct tgatggatag ctggttcacc caagctccct
    14641 tgctacgcag cttgatggct aaaggcttgc acgtcattgg gatgatcaaa gacatgaagc
    14701 agcgctaccg attagacgac aagcgaatga ctctgaaaga actctatgtg aagctttcac
    14761 gatcctccaa aacggagatc ttgggatcgg ttcttacccg aaccgattgt gggttgccta
    14821 tcaagttagt tttcgtccaa aaccggaatt gccgtagaga atggctcgct attttgagca
    14881 cagatatcga actcgcagat gccgaaattg tccgtattta tggcatccgc tggagcattg
    14941 aaaccttctt caagttcacc aaatcttatt tgaagctggg aaccgagttc cagggtcgct
    15001 cttttgacat gttgatcagc cacaccaccc ttgttttcac tcgttacctg gtgatggaat
    15061 gggagcgacg cgagcatcag gatcaacgtt ctttgggcgg gttgtttttt ctgttttcgg
    15121 atgaagtccg tgatctggat ttgaaagccg cgttacaaca aatcgtcagc tttttcattg
    15181 agcttactca aacgaagacc aaacagggga agtcggccat tttaagtcaa gtccagcaat
    15241 ggatttcagg tttacccagc tacatcaagg ctttaatgcc aaatttgagc tgcgaaactt
    15301 gagtaaataa aaagattgtg taaggaaaaa aagtccggct ggctgtattg ttagtggtga
    15361 aagaagacaa agggggatta gccatgaaga catggacgcc attattgctt gccggggcgc
    15421 ttgcggcggg agcggccggc tgctcgcaag gaaacagcgc atccggcgat gcgccgagcg
    15481 gaagcaaaga accgctgacg atcaatatga tgacgacgag ctacgccggg ggcggctggc
    15541 cggaagatca tccgattatt aaggaaatcg acaagaagct gaatattaat ttgaaggtgc
    15601 agtgggttcc ttcagacacc tactcccaga agctgaacgt gatggcggct tccaacgatt
    15661 ttcccgacgt attctacgtt ccggaggcgg agttcaacaa gtggcgggat aagggcgtct
    15721 ttatggacgt gaagcctgag ctcggcaact atgcgaattt gacgaagtac attccggccg
    15781 acgcgatggc taagatgaat ccgaaagaca aatattacgg gtttccttat tatgtaaccg
    15841 atacgcggga tacattagcg attcgcaaag actggctcga taagctgggg ctgaagatgc
    15901 cgacgacgac ggatgaattt tacgaggtgg ccaaggcgtt cgcaacgaaa gatccggacg
    15961 gcaacggcca ggcggatacg ccgggattct cgttcggcat cgtcaataac aagttctcgc
    16021 aaatcgaacc gattatgggc gccttcgggc tgggcaatga ttgggccgag atcaacggcc
    16081 aactggtgcc gatgcaggtg cagacggagg aattgaagca gttcgccgct ttcatgcaaa
    16141 aagcttacgc cgaaggcgtc atggacaagg attttccggc caataagctg aaggacagcg
    16201 tagccaagct ggaagcgggc aaaacgggca tcgcgatgat cgtaaccaac gaatttttta
    16261 acgggacgct gccgacgctg aagaagctga ccccgagcgc cgagctcgtg cagctgcttc
    16321 ctcccaaagg cccgtcggga aagcagacga gtcagacgct gcagatgacc aataagatcg
    16381 tcatcaacgc caaaatcgac gcggccaaaa agcagcgtat tttgcaaatg ctggactata
    16441 tgctgtccga cgagggctac gatctgatca agaacgggat cgaaggcgtg cattatacga
    16501 agagcggcga cggcaagttc cagaagctgg aggcgttcga taaagaccgt ccgcagctgt
    16561 tgtccacttg gtttttccgc agatttgatc cgggcattca aattcgcaag tgggacgatc
    16621 aggaagtcgc gcaaaaaatt aaaacgatta tcgacgccaa cgagaagttc cgctggacca
    16681 atcccgccga agggttcttt agcgaaacga tgaccaaaaa aggtgcgaat ctgcagcaaa
    16741 agtggatgga aacgatgacc aaggtcattg tcggccaagc tccgcttgcg gcgatcgacg
    16801 atgcggcggc cgcctggaag cgggatggcg gcgacgagat tattaaggaa atcaacgcgc
    16861 aataccagac gctgaaataa ccggttgcgc gatgctacag ggcaggcggc gtgccaagcc
    16921 cgccggccct tatgaacgag ggagtgatcg acatgcagaa ggccgtcaaa cagggaatcc
    16981 ctttatatat tatgattttg cccgacctgc tctattttct tctgtttcgt tatgcgccga
    17041 tggggggcat cattctggct tttaaagact ttgatccttt cgaaggcata tgggcgagcc
    17101 catgggttgg tttcaagcat ttccaggttt tgtttagcga gcccgacttt tggcggctgc
    17161 ttaccaatac gctgatgtta agcgctctca atttatttct gtattttccc gtgccgattg
    17221 ttattgccgt gttattgaac gaagcccgga tcaaatggtt tgccaaaacc gttcagacgg
    17281 tcgtctacat cccgcatttc gtatcatggg tagtcgtcgt cggcattacg gtcgtgctgt
    17341 tcgcttcgca agacggcggc gtcaacaagc tgctcgccga atacggatgg tcccgcatcg
    17401 atctgctgac cgatccgggc tacttcagag ctctgtatgt gctgcaaagc atttggaagg
    17461 agacgggctg gggaacgatc atcttcctgg cggcgctggc ttcgatagac cctaccttat
    17521 atgaagcggc cgttatggac ggggcgggaa gatggagaca gatgtggcat attacgctgc
    17581 ccgcgctcag gacgattgcc gtgctgctgt tcattctcag actcggacag gtgatggatt
    17641 ccggcttcga gcatatttac ttgctgcaaa attcgctgaa cctggccgta tcggacgtat
    17701 tcgacacgta tgtgtaccgc cagggcgttc ttcaagggga atacagcttc actacggcga
    17761 tcgggctgtt caaatcgatt gtcgggttaa tcttcgtact tgcggccaac aagctggcca
    17821 aacgattcgg cgaggagggc gtctactgac atgaataaac tagtggccgg aaaacgcgac
    17881 atattgttca atctgctcat ctacgggctg cttgcctttt cgctgctcgt tgtcctttta
    17941 ccgtttcttt acgtgctgtt cagctcgttt tccacgaagg cggaatattt atcgcgagga
    18001 ttttatttgt tcccccggga atggacgttc aactcgtatg ggtatttgac caataataaa
    18061 ggcttcttat cgtcctatgc aaatacgctg tacattacgg ccgtcggcac cgcgatcaat
    18121 gttttcgtca cttgcttaat ggcctacggc ttgtccaaaa gctggctgag aggaagaagc
    18181 tggctcaact ttatggtgct gttcacgatg atttttaacg gagggatgat tcctacgtat
    18241 ctcgtattga aggagctttc gctgatcaac acctactggg cgctgtttct gagcggggcg
    18301 gtcgctccgt tcgtgctcat catcatgaga agcttcttct ccaccatccc ggcggagctg
    18361 gaagagtcgg cgcgcatcga cggatgcagc gaatggcggc tgttattcag catcgtcatc
    18421 ccgctgtcgc ttccatcgat cgtcacggtg acgctgctct acggggtcgc ccattggaac
    18481 gcttatttcc aggcgatctt atacttgaac gattccgcca aatggccggt gcaggtgttt
    18541 ttgcgccagc tgctgctgga aaccgactct tcgatggagc tgaatatcgg cgactacgag
    18601 tatggacctc ccgtccgcat ggccgccgtg atcgcaacgg cgctgccgct gctgctatgc
    18661 tacccgtttc tgcagaaata ttttaacaaa ggcatgttcg tcggttcggt caaaggataa
    18721 agcttgggga gaaaggggcg cattagcgat gaaagcgatc gttatattaa tggatacgtt
    18781 aaaccggcaa ttgcttgaga tgtatgaccc ggcgagttgg gtacggacgc cgaacttgtc
    18841 gagactggcg gagaaatgcg cggtcttcga ccagcattgg tccggctctc tgccgtgcat
    18901 gccggcgcgt agggatatgt tcacagggcg gctcgggttt ctggaacgcg gctggggcgg
    18961 tctggagccg ttcgatgtga cgctgccgca ggtactgaag cgccatcgca tattttccca
    19021 tatagtgacc gatcactacc attattttaa aacgggcggg gaaaattact gccaagcctt
    19081 cagcagctgg gatttgcacc gggggcagga gagcgatccc tgggtttccc gggttcgcga
    19141 tccggcatcc ctgcaagagc cgcactatgg cagagtggag ccgcaatacg agaaaaaccg
    19201 cgccgccttt cggcgcgagg aggattatcc ggggccgaga acgatgagcg cggcatgttg
    19261 ctggctggaa gataataaag aggcggagtc gttcttcctg atggtggaag ccttcgatcc
    19321 gcacgagccg ttcgattgcc cgcagcatta tttggcgatg tacggcgacg actatacggg
    19381 tccaaggatg gagtggccca agtattccag agtaagcgag ccgccggaag cgatagagca
    19441 tctgcggaag cgttatgcgg ccaatctgac gatgatcgat cattggctcg ggaaactgct
    19501 cgacacgatg gatcataacg gcctgtggga cgatacgctg ctgattatga cgacggatca
    19561 cggctttctg ttaggcgaac atgactggac gggcaaaaat atcatgcatg tgtacaacga
    19621 aatcgcccat ctgccgctga tggttcacgt gccgggaacg gctgtcgccg gcacgcggat
    19681 ttcggcgata acgcaaaaca tcgatataat gccgacgatc ctcgattatt tcggcatcga
    19741 tattccgccg tcgacaagag ggaagtcctg gctgccgctg cttgacggca ccgcgcagaa
    19801 gctgcgcgat tgcgcactct acggcatgtt cggcatgacg gtgaatataa cggacggcgc
    19861 ctacacctat ctgcgcgctc ccgtccgcga ggataacgtc ccgtgctatg cgtatacggc
    19921 catgccgacg acgttcggtt cgtttctcgg cgcttccgtc cctgagcaga tcgagaccgg
    19981 cagatttctg tcttacacgg cgtttccggt ttaccggatt cccgtcagcc aagcgggcgt
    20041 tcccttcaag atggcgcagc acgggcagcg ctctctgctc tattctatgg aagccgatta
    20101 ccgtcaagcc gcgcccgtcg aggacgaagg gctgatccgc tcgtatacgg agctgctgat
    20161 tcgcgccatg gagctcgaac aagctcccga agagcagtat gagcgactcg gattgaagcc
    20221 ggggaaccgg taaaaaacga tgaatacgga ggatgaacga tgagaatgtt atttctggat
    20281 ttggattcca ccagccccga ccatttggga tgttacggtt atcatcgcaa tacgtcgcct
    20341 aacattgaca aaattgcggc cgagggtatc cgctttacga attattacac ttccgacgcg
    20401 ccctgcgccc cgtcgagaac ggcgctgatg accggacagt tcggcatccg caacggcctg
    20461 gtcggccacg gcggcaccgc cggcgacatg aagctggaag gggagaagcg cgagctgatg
    20521 ggcaggctga cgcgaggcgg cgccctgcct tcgtatttga atttggcggg caatctgaac
    20581 acggtgctga tcagcccgtt cgcccagcgc cattcgacct ttcacttcta tgcgggcttt
    20641 aacgaaatta tcaataccgg caaatacggc aatgaatccg ccgagcatgt aacgcctgtg
    20701 gcgctggact ggatcgagcg caacgcgaag aaggacgact ggttcctcta tatcaactat
    20761 tgggacccgc atacgcctta ccgcgtgccg atggagta
//
