LOCUS       NZ_CP026036            20747 bp    DNA     circular CON 16-JUN-2024
DEFINITION  Bacillus subtilis strain PK5_16 chromosome, complete genome.
ACCESSION   NZ_CP026036
VERSION     NZ_CP026036.1
KEYWORDS    RefSeq.
SOURCE      Bacillus subtilis
  ORGANISM  Bacillus subtilis
            Bacteria; Bacillota; Bacilli; Bacillales; Bacillaceae; Bacillus.
REFERENCE   1  (bases 1 to 4040032)
  AUTHORS   Albokhari,A., bougouffa,s., Essack,m., Andres-Barrao,C., Saad,M.,
            Bajic,V.B. and Hirt,H.
  TITLE     Plant growth-promoting Bacillus that were isolated from Pakistan
            desert
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 4040032)
  AUTHORS   Albokhari,A., bougouffa,s., Essack,m., Andres-Barrao,C., Saad,M.,
            Bajic,V.B. and Hirt,H.
  TITLE     Direct Submission
  JOURNAL   Submitted (17-JAN-2018) Hirt's Lab, King Abdullah University of
            Science and Technology, Thuwal, Jeddah, Makkah 23955-6900, Saudi
            Arabia
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: 20-OCT-2017
            Assembly Method                   :: smrtanalysis v. 2.3.0.140936.p5
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 94x
            Sequencing Technology             :: PacBio
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_023521475.1-RS_2024_06_15
            Annotation Date                   :: 06/15/2024 05:08:38
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 4,156
            CDSs (total)                      :: 4,035
            Genes (coding)                    :: 3,931
            CDSs (with protein)               :: 3,931
            Genes (RNA)                       :: 121
            rRNAs                             :: 10, 10, 10 (5S, 16S, 23S)
            complete rRNAs                    :: 10, 10, 10 (5S, 16S, 23S)
            tRNAs                             :: 86
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 104
            CDSs (without protein)            :: 104
            Pseudo Genes (ambiguous residues) :: 0 of 104
            Pseudo Genes (frameshifted)       :: 76 of 104
            Pseudo Genes (incomplete)         :: 44 of 104
            Pseudo Genes (internal stop)      :: 18 of 104
            Pseudo Genes (multiple problems)  :: 30 of 104
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 09:26:44
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 3063759
            Orig. end                         :: 3084506
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP026036.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..20747
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="CDPS"
                     /region_number="10"
                     /rules="CDPS"
                     /tool="antismash"
     cand_cluster    1..20747
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="CDPS"
                     /kind="single"
                     /product="CDPS"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..20747
                     /aStool="rule-based-clusters"
                     /category="NRPS"
                     /contig_edge="False"
                     /core_location="[10000:10747](-)"
                     /cutoff="5000"
                     /detection_rule="CDPS"
                     /neighbourhood="10000"
                     /product="CDPS"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..10747)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="5000"
                     /detection_rule="CDPS"
                     /neighbourhood="10000"
                     /product="CDPS"
                     /protocluster_number="1"
     gene            complement(435..1367)
                     /gene="hprK"
                     /locus_tag="C2H93_RS15645"
                     /old_locus_tag="C2H93_15660"
     CDS             complement(435..1367)
                     /GO_function="GO:0000155 - phosphorelay sensor kinase
                     activity [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_process="GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /GO_process="GO:0006109 - regulation of carbohydrate
                     metabolic process [Evidence IEA]"
                     /codon_start=1
                     /gene="hprK"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391380.1"
                     /locus_tag="C2H93_RS15645"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C2H93_15660"
                     /product="HPr(Ser) kinase/phosphatase"
                     /protein_id="WP_003228097.1"
                     /transl_table=11
                     /translation="MAKVRTKDVMEQFNLELISGEEGINRPITMSDLSRPGIEIAGYFT
                     YYPRERVQLLGKTELSFFEQLPEEEKKQRMDSLCTDVTPAIILSRDMPIPQELIDASEK
                     NGVPVLRSPLKTTRLSSRLTNFLESRLAPTTAIHGVLVDIYGVGVLITGKSGVGKSETA
                     LELVKRGHRLVADDCVEIRQEDQDTLVGNAPELIEHLLEIRGLGIINVMTLFGAGAVRS
                     NKRITIVMNLELWEQGKQYDRLGLEEETMKIIDTEITKLTIPVRPGRNLAVIIEVAAMN
                     FRLKRMGLNAAEQFTNKLADVIEDGEQEE"
     misc_feature    1479..1494
                     /note="TFBS match to DasR, N-acetylglucosamine dependent
                     repressor, confidence: medium, score: 21.26"
                     /tool="antismash"
     gene            1549..2739
                     /gene="nagA"
                     /locus_tag="C2H93_RS15650"
                     /old_locus_tag="C2H93_15665"
     CDS             1549..2739
                     /EC_number="3.5.1.25"
                     /GO_function="GO:0008448 - N-acetylglucosamine-6-phosphate
                     deacetylase activity [Evidence IEA]"
                     /GO_process="GO:0006044 - N-acetylglucosamine metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /gene="nagA"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Amidohydro_1"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391381.1"
                     /locus_tag="C2H93_RS15650"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C2H93_15665"
                     /product="N-acetylglucosamine-6-phosphate deacetylase"
                     /protein_id="WP_249852323.1"
                     /sec_met_domain="Amidohydro_1 (E-value: 5e-42, bitscore:
                     142.2, seeds: 57, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAESLLIKDIAIVTENEVIKNGYVGINDGKISTVSTERPKESYSK
                     EIQAPANSVLLPGMIDIHIHGGYGADTMDASFSALDIMSSRLPEEGTTSFLATTITQEH
                     GNISQALVNAREWKAAEESSLLGAELLGIHLEGPFVSPKRAGAQPKEWIRPSDVSLFRK
                     WQQEAGGLIKIVTLAPEEDQHFELIRHLKEESIIASMGHTDADSAMLSDAAKAGASHMT
                     HLYNAMSPFHHREPGVIGTALAHDGFVTELIADGIHSHPLAAKLAFLSKGSSKLILITD
                     SMRAKGLKDGVYEFGGQSVTVRGRTALLSDGTLAGSILKMNEGARHMREFTNCSWTDIA
                     NITSANAAKQLGIFDRKGSVTVGKDADLVIVSSDCEVILTICRGNIAFISKEADQI"
     gene            2736..3464
                     /gene="nagB"
                     /locus_tag="C2H93_RS15655"
                     /old_locus_tag="C2H93_15670"
     CDS             2736..3464
                     /EC_number="3.5.99.6"
                     /GO_function="GO:0004342 - glucosamine-6-phosphate
                     deaminase activity [Evidence IEA]"
                     /GO_process="GO:0006044 - N-acetylglucosamine metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /gene="nagB"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391382.1"
                     /locus_tag="C2H93_RS15655"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C2H93_15670"
                     /product="glucosamine-6-phosphate deaminase"
                     /protein_id="WP_163117120.1"
                     /transl_table=11
                     /translation="MKVMECQTYEELSQKAARITADTIKEKPDAVLGLATGGTPEGTYR
                     ELIRLHQTENLSFQNVTTVNLDEYARLSSDDPNSYHFYMNDRFFQHIDSKPSRHFIPNG
                     NADDLEAECRRYEQLVDSLGGTDIQLLGIGRNGHIGFNEPGTSFKSRTHVVTLNEQTRQ
                     ANARYFPSIESVPKKALTMGIRTILSSKRILLLISGKSKAEAVRKLLEGNISEDFPASA
                     LHLHSDVTVLIDREAASLRP"
     gene            3482..4213
                     /gene="nagR"
                     /gene_synonym="yvoA"
                     /locus_tag="C2H93_RS15660"
                     /old_locus_tag="C2H93_15675"
     CDS             3482..4213
                     /codon_start=1
                     /gene="nagR"
                     /gene_functions="regulatory (smcogs) SMCOG1136: GntR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /gene_synonym="yvoA"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391383.1"
                     /locus_tag="C2H93_RS15660"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C2H93_15675"
                     /product="N-acetylglucosamine utilization transcriptional
                     regulator NagR"
                     /protein_id="WP_014478108.1"
                     /transl_table=11
                     /translation="MNINKQSPIPIYYQIMEQLKTQIKSGELQPDMPLPSEREYAEQFG
                     ISRMTVRQALSNLVNEGLLYRLKGRGTFVSKPKMEQALQGLTSFTEDMKSRGMTPGSRL
                     IDYQLIDSTEELAAILGCGHPSSIHKITRVRLANDIPMAIESSHIPFELAGELNESHFQ
                     SSIYDHIERYNSIPISRAKQELEPSAATTEEANILGIQKGAPVLLIKRTTYLQNGTAFE
                     HAKSVYRGDRYTFVHYMDRLS"
     gene            complement(4234..8103)
                     /gene="yvnB"
                     /locus_tag="C2H93_RS15665"
                     /old_locus_tag="C2H93_15680"
     CDS             complement(4234..8103)
                     /GO_function="GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="yvnB"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391384.1"
                     /locus_tag="C2H93_RS15665"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C2H93_15680"
                     /product="metallophosphoesterase"
                     /protein_id="WP_120027539.1"
                     /transl_table=11
                     /translation="MRKYTVIASILLSFLSVLSGGHHESKAFPVVQQELFQTPHYIPLL
                     ENPPQIDVKAEMRNNLMIEAQVRDNSYQAFSAFLFYKQSNELGYKMVPMDPTPGAVRKF
                     LAQIPKRLIWNSELEYYIVMSNGKQRVESETKKLKLEGYQADLAHIPELLITELAVDTK
                     NIGRADGYEFIEIFNTTDRTIDFKDYHIRYRYPKEGPDSDLIWRPDERILIPSGETFVV
                     WLKPAGHPELTSEDFNRYYQTQLKEGKNLAVIDETEGMANTRPRAVVISTNTGKDISVA
                     HYRKHALRRLSSVLYKYPLNGTAELLNISIGEKNPSPGTVLQAQVPEQKRKIKLDKEKP
                     VIEDLTDRKPVRPAESIELRADIRDRSLVKTAAFYYRTDENKPFKRILAEKDRNDNLYH
                     YIVYSPELIGKDQLEYYVAAGDGINEARTPVKMIDIKQTSKSHGLRMNIENRDTLSGTQ
                     FLKATTEGRADRIKLWIDGKKQVTEPAMEKEVYFAFDTRKTNLYFKNAVTMEGKVLKVF
                     DDTTNKYRTYSVPLPETLLRKGKQLQRITIRSGSKVSPFDTAENRDDFLVKNARLVLSD
                     GTVIRDQRVSPEKELFIGDNQRSNKSWQFQFNLPDGLFTSQLLEWDTSKLSEGAHHIQA
                     SDGKENVSLVVRVDNSGPHIEPNITEGQTYKGNLILQADMYDKWSKIEEAEASLDGESI
                     TLPYHTSSSDLLPGKHSLKVTATDLAGNKTVIERTFKTEREHPDQPEVIDSDADTHKAK
                     LSVRVKDPTNDAMDVGFYRGFQYTARNHVKIFKHASLTEPPKSFVPERETPFTNKELER
                     VSAADGKTVSTENKELFPYHRFEVTVDPSIDENDLAEAVWKGSSLPGRKVTMYAWNYRT
                     NEWQPVDSFVAKDDKPFTLKASVIAADFVRESKMNVIVQDEIPPAKDMYTFVWMSDTQY
                     YAESYPHIFDKQTEWIKDNQKQLNIKYVFHTGDIVDDSADIRQWKNADRSMSVLDKSGI
                     PYGVLAGNHDVGHKDGSYRAFGKYFGSDRFDKKLHYGGSYKNNRGHYDLISSNGNDYIM
                     LYMGWGITDQDIAWMDQVLKKHPDRMAILAFHEYLLVSGNRSPIGEKIFKEIVKPNPNV
                     VMVLSGHYHSAMRKTDELDDDGDGKPDRLVHQMLADYQGGPEGGQGYLRLLQFDQANDM
                     VHVSTYSPYVKDKNYYDTDTYGNKDEFSLSLDLKPRIKKVETDYFECNVYTNEELGKRE
                     QVKSGDTAEFRWDHLEPQSVYYWYIIVEDSFNGKTKSPIWKFKTKKETYRPAPDQFDFR
                     HVSNP"
     gene            8268..8729
                     /gene="yvnA"
                     /locus_tag="C2H93_RS15670"
                     /old_locus_tag="C2H93_15685"
     CDS             8268..8729
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /gene="yvnA"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391385.1"
                     /locus_tag="C2H93_RS15670"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C2H93_15685"
                     /product="MarR family transcriptional regulator"
                     /protein_id="WP_021480697.1"
                     /transl_table=11
                     /translation="MNNSIHDELFQAIQQFALKRDKRVWQKVQIPSSQHLDHLKKDWTL
                     TQLHIVSCLHTSKNVNNSFLASRLHISKAAVSKAIQALLKHNIITVTKKPGNKKEIFYT
                     LTESGKELAGLHERLHQKAKEQYKQLFNEFSIDELKTVTAFINLWIKHM"
     gene            complement(8768..9985)
                     /gene="cypX"
                     /locus_tag="C2H93_RS15675"
                     /old_locus_tag="C2H93_15690"
     CDS             complement(8768..9985)
                     /EC_number="1.14.15.13"
                     /codon_start=1
                     /gene="cypX"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) p450"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1007: cytochrome P450"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391386.1"
                     /locus_tag="C2H93_RS15675"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C2H93_15690"
                     /product="pulcherriminic acid synthase"
                     /protein_id="WP_021480698.1"
                     /sec_met_domain="p450 (E-value: 3e-36, bitscore: 123.0,
                     seeds: 50, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSQSIKLFSVLSDQFQNNPYAYFSQLREEDPVHYEESIDSYFISR
                     YHDVRYILQHPDIFTTKSLVERAEPVMRGPVLAQMHGKEHSAKRRIVVRSFIGDALDHL
                     SPLIKQNAENLLAPYLERGKIDLVNDFGKTFAVCVTMDMLGLDKRDHEKISEWHSGVAD
                     FITSISQSPEARAHSLWCSEQLSQYLMPVIEERRVNPGSDLISILCTSEYEGMAMSDKD
                     ILALILNVLLAATEPADKTLALMIYHLLNNPEQMNDVLADRSLVPRAIAETLRYKPPVQ
                     LIPRQLSQDTVVGGMEIKKDTIVFCMIGAANRDPEAFEQPDVFNIHREDLGIKSAFSGA
                     ARHLAFGSGIHNCVGAAFAKTEIEIVANIVLDKMRNIRLEEDFCYAESGLYTRGPVSLH
                     IVFDRA"
     gene            complement(10001..10747)
                     /gene="pchC"
                     /locus_tag="C2H93_RS15680"
                     /old_locus_tag="C2H93_15695"
     CDS             complement(10001..10747)
                     /EC_number="2.3.2.22"
                     /codon_start=1
                     /gene="pchC"
                     /gene_functions="biosynthetic (rule-based-clusters) CDPS:
                     CDPS"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391387.1"
                     /locus_tag="C2H93_RS15680"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C2H93_15695"
                     /product="cyclo(L-leucyl-L-leucyl) synthase"
                     /protein_id="WP_021480699.1"
                     /sec_met_domain="CDPS (E-value: 1.9e-83, bitscore: 277.4,
                     seeds: 17, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTGMVTERRSVHFIAEPLTENCREIFERRRHVLVGISPFNSRFSE
                     DYIYRLIGWAKAQFKSVSVLLAGHEAANLLEALGTPRGKAERKVRKEVSRNRRFAERAL
                     VAHGGDPKAIHTFSDFMDNKAYQLLRQEVEHAFFEQPHFRHACLDMSREAIIGRARGVS
                     LMMEEVSEDMLNLAVEYVIAELPFFIGAPDILEVEETLLAYHRPWKLGEKISNHEFSIC
                     MRPNQGYLIVQEMAQMLSEKRITCEG"
     misc_feature    10873..10888
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: weak, score: 21.5"
                     /tool="antismash"
     misc_feature    10875..10889
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: medium, score: 22.98"
                     /tool="antismash"
     misc_feature    complement(10876..10891)
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: weak, score: 22.77"
                     /tool="antismash"
     gene            11173..11682
                     /gene="pchR"
                     /locus_tag="C2H93_RS15685"
                     /old_locus_tag="C2H93_15700"
     CDS             11173..11682
                     /codon_start=1
                     /gene="pchR"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391388.1"
                     /locus_tag="C2H93_RS15685"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C2H93_15700"
                     /product="pulcherriminic acid biosynthesis transcriptional
                     regulator PchR"
                     /protein_id="WP_003228073.1"
                     /transl_table=11
                     /translation="MSDLTKQMIYDIYVRLLHLNEQKANTSLQQFFKEAAEEDVAEIPK
                     NMTSIHVIDCIGQHEPINNAGIARKMNLSKANVTKISTKLIKEEFINSYQLTDNKKEVY
                     FKLTRKGRRIFDLHEKLHKKKELAFYQFLDSFSQEEQKAVLKFLEQLTSTLEAEQTDGT
                     PDKPVK"
     gene            11703..12914
                     /gene="pchE"
                     /locus_tag="C2H93_RS15690"
                     /old_locus_tag="C2H93_15705"
     CDS             11703..12914
                     /codon_start=1
                     /gene="pchE"
                     /gene_functions="transport (smcogs) SMCOG1106: major
                     facilitator transporter"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391389.1"
                     /locus_tag="C2H93_RS15690"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C2H93_15705"
                     /product="MFS transporter"
                     /protein_id="WP_003228068.1"
                     /transl_table=11
                     /translation="MAHTKSKAVLILYTVCFSAFFASLSQNIYSPILPIIKESFHVSTA
                     MVNLSVSVFMIVTAIMQIILGAIIDFKGARIVLITGILATAAASIGCAVTTDFTLFLIF
                     RMIQAAGSAALPLIAATTIGQLFTGNERGSAMGTYQMLLSVAPAIAPVLGGFIGGAAGY
                     EGIFWILAAISIVLLVTNSITFPKDSPTESMQQAKGNVFAHYKSIFTNRTGNVILTLSF
                     VLFFIYFAVIVYLPILLTEHYHIDVGIAGLLYLPLALSTIAGTFLFKRIQAKIGLHTLF
                     IGSNVIAACSIILFAVTHSVSLVLMALTLALFGISMGVIPPLYSTMITNEFEHNRGSAI
                     GMFNFIRYTGMAAGPMVSAYLLTMMPSAMSFSLLGLGFAALSFCLLPPMFSPQKRTKQK
                     KHHM"
     gene            complement(12942..13301)
                     /gene="yvlD"
                     /locus_tag="C2H93_RS15695"
                     /old_locus_tag="C2H93_15710"
     CDS             complement(12942..13301)
                     /GO_component="GO:0005886 - plasma membrane [Evidence IEA]"
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /gene="yvlD"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391390.1"
                     /locus_tag="C2H93_RS15695"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C2H93_15710"
                     /product="phage holin family protein"
                     /protein_id="WP_003228066.1"
                     /transl_table=11
                     /translation="MVKWAVSILVNALLLIVIDGYIDSIHISSIGAAIIASLILSILNV
                     LIKPLLIIFTLPVTMVTLGLFLFVINAITLMMTASIMGDSFQIDGFGTAIWASVILSVF
                     HLLIQKGILEPLRKK"
     gene            complement(13303..13500)
                     /gene="yvlC"
                     /locus_tag="C2H93_RS15700"
                     /old_locus_tag="C2H93_15715"
     CDS             complement(13303..13500)
                     /codon_start=1
                     /gene="yvlC"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391391.1"
                     /locus_tag="C2H93_RS15700"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C2H93_15715"
                     /product="PspC domain-containing protein"
                     /protein_id="WP_003228065.1"
                     /transl_table=11
                     /translation="MNKLYRSEKNKKIAGVIGGLAEYFNWDASLLRVITVILAIMTSVL
                     PVLLIYIIWIFIVPSERDMK"
     gene            complement(13505..14602)
                     /gene="yvlB"
                     /locus_tag="C2H93_RS15705"
                     /old_locus_tag="C2H93_15720"
     CDS             complement(13505..14602)
                     /codon_start=1
                     /gene="yvlB"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391392.1"
                     /locus_tag="C2H93_RS15705"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C2H93_15720"
                     /product="DUF4097 domain-containing protein"
                     /protein_id="WP_249852324.1"
                     /transl_table=11
                     /translation="MKQEKERILKLVEEGKLTAQEALTLIEKLDSDYKEKEEKITALSV
                     HVHDEEEPFTTAKKESGKPSLGAKLFDWIDSAVKKVKEVDLDLNFGHAYDVQHIFQFKD
                     TDFSSVELQIANGSVNIVPWEDDDIRAECQAKVYRADSQDAARLAFLQHIECEIKGNKF
                     FIRTEKKTMKTNVTLYIPQKEYDKIRVKLFNGPVRGEHLHVKEFSAKTTNGVLSFSHLT
                     AEKAIAETANGQIKLASHSCGTIEAETINGLIDLRGKSESIDVQSFNGNIAINVTESDC
                     RSIYAKTTTGSVELAIPDDLAVKAELKSNLGSLSHELMDVEMLKEKNDTIQKEMMFTSN
                     QAHDQNITVFSESLTGAIKLKYSQR"
     gene            complement(14627..14953)
                     /gene="yvlA"
                     /locus_tag="C2H93_RS15710"
                     /old_locus_tag="C2H93_15725"
     CDS             complement(14627..14953)
                     /codon_start=1
                     /gene="yvlA"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391393.1"
                     /locus_tag="C2H93_RS15710"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C2H93_15725"
                     /product="protein YvlA"
                     /protein_id="WP_003244375.1"
                     /transl_table=11
                     /translation="MNRNQAIIASLCYFSVFIAPIIVPIVAYFVVNEKETKRHAIRSLI
                     SHIVPFVGWLFLFIALLGGAVAIDGDSLLPVFVIIGGAVIYFLVVIGIIIWNVIQGIKV
                     LRAA"
     gene            15171..15401
                     /locus_tag="C2H93_RS15715"
                     /old_locus_tag="C2H93_15730"
     CDS             15171..15401
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391394.1"
                     /locus_tag="C2H93_RS15715"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C2H93_15730"
                     /product="hypothetical protein"
                     /protein_id="WP_003235419.1"
                     /transl_table=11
                     /translation="MEKDPSDYTVTQESVLKLIHEQKRMNREMIAELEQIHGPFPISHD
                     IQYIKVLLDSSNTHIVQDLMSVSKQLYKKTL"
     misc_feature    complement(15187..15202)
                     /note="TFBS match to AfsQ1, Two-component system AfsQ1-Q2,
                     activator of antibiotic production, confidence: medium,
                     score: 17.68"
                     /tool="antismash"
     gene            complement(15599..16420)
                     /gene="hag"
                     /locus_tag="C2H93_RS15720"
                     /old_locus_tag="C2H93_15735"
     CDS             complement(15599..16420)
                     /codon_start=1
                     /gene="hag"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391416.1"
                     /locus_tag="C2H93_RS15720"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C2H93_15735"
                     /product="flagellin Hag"
                     /protein_id="WP_029318328.1"
                     /transl_table=11
                     /translation="MRINHNIAALNTLNRLSSNNSASSKNMEKLSSGLRINRAGDDAAG
                     LAISEKMRGQIRGLEMASKNSQDGISLIQTAEGALTETHAILQRMRELTVQAGNTGTQQ
                     TEDLTAIKDEMDALTEEIDGISQRTEFNGKKLLDGSETAGFTFQIGANAGQNINVTIGN
                     MDATTLGVKGIDVSADDFSFDTEIVKIDSAITSVSNQRAKLGAVQNRLEHTINNLGASS
                     ENLTAAESRIRDVDMAKEMSDFTKNNILSQASQAMLAQANQQPQNVLQLLR"
     gene            complement(16757..19630)
                     /gene="uvrA"
                     /locus_tag="C2H93_RS15725"
                     /old_locus_tag="C2H93_15740"
     CDS             complement(16757..19630)
                     /EC_number="3.1.25.-"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /GO_process="GO:0006289 - nucleotide-excision repair
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="uvrA"
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391396.1"
                     /locus_tag="C2H93_RS15725"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C2H93_15740"
                     /product="excinuclease ABC subunit UvrA"
                     /protein_id="WP_003228057.1"
                     /transl_table=11
                     /translation="MAMDRIEVKGARAHNLKNIDVTIPRDQLVVVTGLSGSGKSSLAFD
                     TIYAEGQRRYVESLSAYARQFLGQMDKPDVDAIEGLSPAISIDQKTTSRNPRSTVGTVT
                     EIYDYLRLLYARVGKPHCPEHGIEITSQTIEQMVDRILEYPERTKLQVLAPIVSGRKGA
                     HVKVLEQIRKQGYVRVRIDGEMAELSDDIELEKNKKHSIEVVIDRIVVKEGVAARLSDS
                     LETALRLGEGRVMIDVIGEEELMFSEHHACPHCGFSIGELEPRLFSFNSPFGACPTCDG
                     LGMKLEVDADLVIPNQDLSLKENAVAPWTPISSQYYPQLLEAVCTHYGIDMDVPVKDLP
                     KHQLDKVLYGSGDDLIYFRYENDFGQIREGEIQFEGVLRNIERRYKETGSDFIREQMEQ
                     YMSQKSCPTCKGYRLKKEALAVLIDGRHIGKITELSVADALAFFKDLTLSEKDMQIANL
                     ILREIVERLSFLDKVGLDYLTLSRAAGTLSGGEAQRIRLATQIGSRLSGVLYILDEPSI
                     GLHQRDNDRLISALKNMRDLGNTLIVVEHDEDTMMAADYLIDIGPGAGIHGGQVISAGT
                     PEEVMEDPNSLTGSYLSGKKFIPLPPERRKPDGRYIEIKGASENNLKKVNAKFPLGTFT
                     AVTGVSGSGKSTLVNEILHKALAQKLHKAKAKPGSHKEIKGLDHLDKVIDIDQAPIGRT
                     PRSNPATYTGVFDDIRDVFAQTNEAKVRGYKKGRFSFNVKGGRCEACRGDGIIKIEMHF
                     LPDVYVPCEVCHGKRYNRETLEVTYKGKSISDVLDMTVEDALSFFENIPKIKRKLQTLY
                     DVGLGYITLGQPATTLSGGEAQRVKLASELHKRSTGRTLYILDEPTTGLHVDDIARLLV
                     VLQRLVDNGDTVLVIEHNLDIIKTADYIVDLGPEGGAGGGTIVASGTPEEITEVEESYT
                     GRYLKPVIERDKTRMKSLLKAKETATS"
ORIGIN
        1 agttccccca gcggccgatc gcctggccga gcaaaatgct gggcgcggca atgtccgcaa
       61 gcttccagaa cgaaagtttt ttcactctcg aaaacacata acccgttaaa atggcgccga
      121 ttaatccgcc atgaatggca atgccgccct tccaaatctt aatgatttct cccggatgtg
      181 ccgcataata gtcccattca aaggcaacgt aataaattcg cgcgcaaata atcgcaatcg
      241 gaatggcaaa cagaacaaga tcaataaacg tatctttctg cagcccccgt ttttcacttt
      301 ccctcatcgc aatccacagc ccgagcaaag cgccgagacc gataatgatt ccgtaccaat
      361 ggacggctaa cggccccagc tgaaatgcta tcggattgag tggttctatc gcttcattca
      421 tttaacgcca actcctattc ttcttgttca ccgtcttcaa tgacgtccgc cagcttgttg
      481 gtgaattgtt cagcggcatt cagccccatc cgcttcaatc tgaagttcat tgctgccact
      541 tcgatgatga ctgcaagatt tcggcctgga cggacgggaa tcgtcagttt tgtgatttct
      601 gtatcaatga ttttcatggt ctcttcctca agtccgagcc ggtcgtattg cttgccctgc
      661 tcccaaagtt caagattcat gacaatcgtg attcgtttat tgcttctgac cgcgccagcg
      721 ccaaacagcg tcatcacgtt gataatgcca agccccctga tttcaaggag atgctcaatt
      781 aattccggag cgtttcccac aagagtatcc tgatcctcct gccgaatttc aacgcaatca
      841 tcggcgacaa ggcgatgccc tcttttcaca agctccagcg ctgtttcgct ttttccgacg
      901 ccgctctttc ctgtgatcag cacgccgaca ccatatatat cgacaagaac gccatgaatt
      961 gctgtggtag gcgccagcct gctctcaagg aagttggtta aacggcttga cagtcttgtc
     1021 gttttcagcg gcgatctgag gacaggcacc ccatttttct cggaggcgtc aatcagctcc
     1081 tgcgggatgg gcatatctct agaaagaata atagctggtg ttacatcagt gcacagagaa
     1141 tccattcgct gttttttctc ctcttcagga agctgttcaa agaaagaaag ctctgttttt
     1201 ccgagaagct gcacgcgctc tctcgggtaa tatgtaaaat atccggcaat ttcaatgcct
     1261 ggtcttgata ggtcactcat tgtaatcggg cggttaattc cttcttctcc gctgattaat
     1321 tccaaattga actgttccat tacgtctttt gtgcgaacct ttgccacgat atgttcctcc
     1381 tgttccgggc tgccccgagc ttgctcacaa tactttcatt ttatcacttt caggcttgaa
     1441 cctaaaacag attttataaa aggcgggaaa acacctcagc tggtctagat cactagtctg
     1501 aaaaagagta aaataaaggt attcaaattc cagaaaggcg gatcatctat ggcagagagt
     1561 cttcttatca aagacattgc gatcgtgaca gaaaatgaag taatcaaaaa cggctatgtc
     1621 ggaatcaatg acggaaaaat cagcacagtc tcaacagaac ggcccaagga gtcatattca
     1681 aaagaaattc aagcacctgc gaattccgtt ttgcttcccg gcatgattga cattcatatc
     1741 cacggcggct atggcgcaga tacgatggat gcaagctttt ctgcgctcga catcatgtcg
     1801 tcaagacttc ccgaagaagg cacgacgagc tttttagcca caacgattac ccaggaacat
     1861 gggaacattt ctcaagcttt ggtgaacgca agagagtgga aagcggctga agagtcctct
     1921 ttattaggtg cagaactgct cggcattcat ttagagggcc cctttgtttc acctaaaaga
     1981 gccggagcgc agccaaagga gtggattagg ccttcggatg tttcgctttt cagaaagtgg
     2041 cagcaggagg cgggcggact gatcaaaatt gttacacttg cgccggagga ggatcagcat
     2101 tttgaactga tccgccattt gaaagaagaa tcgattatcg cgtccatggg gcacacggat
     2161 gccgattccg caatgctgtc ggatgccgca aaagcagggg cgagccatat gacccatctg
     2221 tacaacgcga tgagcccgtt tcatcaccga gaacccggag tgatcggaac ggcgctggcc
     2281 catgatgggt ttgtgacaga gctaatagcc gatggcatcc actcccatcc tttagcggct
     2341 aagcttgctt ttttgtcgaa aggcagcagc aagctcattt taattaccga ttccatgagg
     2401 gcaaaaggac tgaaagacgg cgtatatgag ttcggcggcc aaagtgtgac ggtaagagga
     2461 cgaacagctc ttctttcaga cggaaccctt gccggttcga tcctcaaaat gaacgagggc
     2521 gcacggcata tgcgtgagtt tacaaattgc tcttggacgg atatagctaa tataacttct
     2581 gcaaacgcgg ccaaacagtt gggcatcttt gaccgaaaag gcagtgtgac tgtgggaaaa
     2641 gatgcagatt tagtgattgt cagcagtgat tgcgaggtga ttctcaccat ttgccgcgga
     2701 aacattgcat ttatatccaa ggaggctgac cagatatgaa agtaatggaa tgtcaaacgt
     2761 atgaagagct aagccaaaaa gcagccagaa taacggcaga tacaatcaaa gaaaaacctg
     2821 atgccgttct cgggttagcg acgggcggca caccggaagg cacttatcgc gagctgatcc
     2881 gcctgcacca aactgagaat ctctcatttc aaaacgtcac tacagttaat ttggatgagt
     2941 acgccagact ttcaagcgat gacccgaaca gctatcactt ctatatgaac gaccgttttt
     3001 ttcagcatat cgacagcaag cctagccggc attttattcc gaatggaaat gcagacgatt
     3061 tggaggccga atgcagacgg tatgaacagc tagtcgattc cctcggcggc actgacattc
     3121 agcttctcgg catcggccga aacggacaca tcggctttaa cgaaccggga acgtctttca
     3181 agtcgcgaac tcatgttgtg acattaaatg agcaaacccg ccaggcgaat gccagatatt
     3241 ttccttccat agaaagcgtg ccgaaaaaag cactgacaat gggaattcga acgattctct
     3301 caagcaaacg cattctgctg cttatttctg ggaaaagcaa agcagaagct gttcgtaagc
     3361 tgttagaagg aaacataagc gaagattttc ccgcatctgc tttgcacctg cattccgatg
     3421 ttacggtttt gattgatcgt gaagccgcgt cattaagacc ttgaaaggaa catgctgact
     3481 tatgaatatc aataaacaat cgcctattcc gatttattat cagattatgg agcaattaaa
     3541 aacccaaatt aagagcggag agctgcagcc ggatatgcct cttccttccg agcgcgaata
     3601 tgccgaacaa ttcgggatca gccggatgac agttcgccag gcgctttcta atttagttaa
     3661 tgaaggcttg ctctatcgcc tgaaagggcg gggcaccttt gtcagcaagc caaaaatgga
     3721 acaagcactt caagggctga caagctttac tgaggatatg aaaagccgcg ggatgacacc
     3781 gggcagcagg ctcattgatt atcagcttat tgattcaact gaggagctcg cggctatatt
     3841 aggctgcggg cacccctcct ctatccataa aatcactcgg gtgcggctgg caaatgatat
     3901 tccgatggcg attgagtcct cacatattcc ctttgagctt gcgggtgaat taaacgaatc
     3961 gcattttcag tcgtcgatct atgatcatat tgaaaggtac aacagcatac cgatttcccg
     4021 tgcaaaacag gagcttgagc caagcgctgc caccacggaa gaagcgaata ttcttggtat
     4081 tcaaaaggga gcgcctgtcc tattaattaa acgaacaaca tatctgcaga acggaactgc
     4141 ttttgagcat gcaaaatccg tatacagagg cgaccgttat acatttgtcc actatatgga
     4201 tcgtctttca taaaaaaaag cctccaaccc tttttaagga ttggagacat ggcgaaaatc
     4261 aaactggtct ggtgccggac gatatgtttc ttttttcgtc ttgaacttcc agatcggtga
     4321 tttcgttttg ccgttaaaac tgtcttccac tataatgtac cagtaataaa cagactgcgg
     4381 ttcaagatga tcccagcgga attcagctgt atccccgctc ttcacttgct cccgttttcc
     4441 gagctcttca ttggtatata cgttacattc aaaataatcg gtttccacct ttttgattct
     4501 tggcttcaaa tcaagtgaaa gggaaaattc atccttgttg ccataggtat ccgtatcata
     4561 gtaattctta tcctttacat acggagaata cgtcgatacg tgcaccatgt catttgcctg
     4621 gtcaaattga agcaaacgca aatatccttg cccgccttct ggcccgccct gataatcggc
     4681 cagcatttga tgcacaagac gatccggctt cccatcacca tcatcatcca gctcatctgt
     4741 ttttctcatc gcactatgat aatgcccgct caataccatc acgacattcg ggttcggctt
     4801 tacgatttct ttgaatattt tctctccgat cgggcttctg tttccgctga ccagcaaata
     4861 ctcatgaaaa gctaaaatgg ccatccggtc agggtgtttc ttcaacacct gatccatcca
     4921 cgcaatgtcc tgatccgtta tgccccatcc catgtacagc atgatataat cattgccgtt
     4981 gctcgaaatc aggtcataat gtccgcggtt atttttatag gaaccgccat aatgcaattt
     5041 tttatcaaaa cgatcgctgc caaaatattt gccaaacgcc ctgtaggagc cgtccttatg
     5101 ccccacatcg tggttgccgg ccagcacgcc gtaaggtatt ccgctcttat ccagaacgga
     5161 cattgaccga tcagcgtttt tccactgtct gatatcagcg gaatcatcta caatatcacc
     5221 cgtgtggaac acatatttga tattgagctg cttttgatta tcttttatcc attctgtctg
     5281 tttatcaaaa atatgcggat agctttcggc gtaatactgt gtatcagaca tccagacaaa
     5341 tgtgtacata tccttcgcag gaggaatttc atcctgtaca atcacattca ttttcgactc
     5401 ccgtacaaaa tcggcggcaa tcacagacgc tttcagcgta aacggtttgt catccttcgc
     5461 gacgaagctg tcaacaggct gccattcgtt tgtccgataa ttccaagcat acatcgtcac
     5521 ctttctcccc ggcaaagaac tgcccttcca gaccgcttct gccagatcat tctcatcaat
     5581 tgatggatca accgtcactt caaagcgatg ataagggaaa agctctttgt tttctgtcga
     5641 tactgttttt ccatcagcag cagatacccg ctccaattct ttattcgtaa atggggtctc
     5701 cctttccggc acaaagcttt tcggcggttc agtcagtgac gcgtgcttaa atattttcac
     5761 atgatttcgc gctgtatatt gaaatcccct ataaaaacca acatccatgg catcattcgt
     5821 cggatctttc acccggacag aaagcttggc cttatgcgtg tcggcatcgc tgtctataac
     5881 ctccggctgg tccggatgct ctcgttcggt tttaaacgtc ctctcaatca ctgttttatt
     5941 gcccgcgaga tccgttgctg tcacttttag agaatgtttt cccggcaaaa ggtcagaaga
     6001 tgacgtatga tatgggagtg taatgctttc tccatctaac gacgcctccg cttcctcaat
     6061 tttgctccat ttatcataca tatccgcctg caggataagg tttcctttat acgtttgccc
     6121 ctcggtgata ttcggctcaa tgtgaggtcc tgaattatct acccgtacaa ccaggctgac
     6181 attttccttc ccgtcgcttg cttgaatatg gtgagcgcct tcagaaagct ttgatgtatc
     6241 ccactccagc agctgtgatg taaatagtcc gtcaggcaga ttgaactgaa attgccagct
     6301 tttatttgag cgctgattat cgccaataaa gagttccttc tcaggggaca ccctctgatc
     6361 cctgatcacc gttccatctg ataacaccaa tcgggcgttt ttgactaaga agtcatcacg
     6421 gttttcagcc gtatcaaacg gagacacctt cgaacccgat cgtattgtaa tacgctgcag
     6481 ctgcttccct ttccgaagca gtgtctctgg caatggaaca gaataggtgc ggtatttatt
     6541 tgttgtatca tcgaacacct tcagcacttt gccttccatc gttaccgcgt ttttaaaata
     6601 aaggttcgtt ttcctcgtat cgaacgcaaa atatacttct ttttccatcg cgggctctgt
     6661 cacttgtttt ttcccgtcaa tccatagctt aatgcggtca gctcgccctt ctgtcgtggc
     6721 tttgagaaat tgagttcccg acagcgtgtc tctgttttca atattcatcc gcagaccgtg
     6781 cgacttgctt gtttgtttaa tatcaatcat tttgaccggc gttctcgctt cattgatccc
     6841 gtccccggcc gccacataat actctagctg atccttcccg atcaattcag gcgaatacac
     6901 aatataatgg tagagattat cgttgcggtc tttttcagca agaattcgct taaacggttt
     6961 gttctcatcc gtccggtagt aaaaggccgc tgttttcact agacttcggt cccgtatgtc
     7021 agcccgcagc tcaatgcttt cagcagggcg gacaggcttg cggtcagtca aatcctcaat
     7081 gaccggcttt tctttatcga gcttgatttt ccgtttctgc tcgggcacct gtgcctgtaa
     7141 tacggttccg ggagacggat tcttttcccc gattgaaatg ttcagaagtt ctgcggttcc
     7201 gttcaacgga tacttataaa gcactgatga cagccggcgc agcgcatgtt tccgataatg
     7261 cgcaaccgaa atgtcctttc ctgtattcgt tgatatcaca acggcccgcg gcctcgtatt
     7321 ggccataccc tctgtctcgt ctatcaccgc gagatttttt ccttctttaa gttgtgtctg
     7381 ataataacga ttgaaatcct ctgacgtcaa ttctggatgc ccggcaggct tcagccagac
     7441 gacaaacgtt tcgccggatg gtatcaagat cctttcatca ggtctccaaa tcagatcgga
     7501 gtcaggccct tcttttgggt agcggtaacg gatatggtag tctttaaaat caatcgttct
     7561 gtcagtcgta ttaaaaatct caataaattc ataaccgtct gcacgtccta tattcttcgt
     7621 atcaaccgcc agctctgtga tcagaagctc cggaatatgg gcaaggtcag cctggtatcc
     7681 ttcaagcttc agtttcttcg tctccgactc cacccgctgc ttcccattcg acatcacaat
     7741 gtaatactca agctcgctgt tccaaatcaa acgtttcgga atttgtgcca aaaacttgcg
     7801 gaccgctccg ggggtcgggt ccatcggcac cattttgtag cccagctcat tactttgttt
     7861 ataaaaaaga aaggcggaaa atgcttgata cgaattatcg cgaacttgag cctcaatcat
     7921 tagattgttt ctcatttcag ctttcacatc aatttgagga ggattttcaa gcaagggtat
     7981 gtaatgaggc gtttgaaata gttcctgctg tacaacagga aaagctttcg attcatgatg
     8041 gccgccagac aaaacggaaa gaaaagacag taatatagaa gcaataaccg tgtatttcct
     8101 catcaaagca cctccctttt catgtatttt gcgtctgaac agggaagctt atgagttcat
     8161 ttttgtgcat aaagaacaaa aaaacgtctg cctcttgaaa attccactat tccccagtaa
     8221 actaaggata gttaaccagt taacaattaa atcagagagg caaattgatg aacaacagca
     8281 ttcatgatga attatttcaa gctatacaac aattcgcatt aaaaagagat aaacgcgtct
     8341 ggcaaaaggt gcagattccg tcctcacaac atctcgacca cctcaaaaaa gactggacat
     8401 tgacccagct tcacattgtt tcctgtttac ataccagcaa aaatgtgaat aacagcttct
     8461 tagcatcccg cttacatatc tcaaaagcag ctgtttcaaa agcaattcaa gctttgttga
     8521 aacataacat cattacagtg acaaaaaagc cgggcaacaa aaaagaaatt ttttatacgt
     8581 taactgaaag cggcaaagaa ctggcggggt tacatgaacg gcttcatcaa aaagcaaagg
     8641 agcaatacaa acagctcttc aatgaatttt caattgatga gttgaaaaca gtgactgcgt
     8701 ttattaactt gtggatcaag catatgtaaa aaagcctcac ccgcacggga gagacctttc
     8761 catattatta agccctgtca aatacaatat gaagtgagac gggtccgcgt gtatacagac
     8821 cggactcagc ataacaaaaa tcttcctcta atctgatatt ccgcatctta tccagcacaa
     8881 tattagctac aatttcgatt tcggttttgg caaaagctgc tcctacacag ttatgaatgc
     8941 cggatccgaa agcgagatgc cgggcggcgc cgctaaaagc gctcttgatg ccaagatctt
     9001 cccgatgaat attaaacacg tcaggctgtt caaatgcttc agggtcccgg ttagccgcac
     9061 cgatcataca aaaaacaatc gtatcttttt tgatttccat accgccgacc actgtatctt
     9121 gggacagctg ccgcggaatc agctgaaccg gcggtttata acgcaatgtc tccgcaatgg
     9181 ctctcggaac taacgaacgg tcagccaaaa catcattcat ctgctcagga ttgttgagca
     9241 aatggtagat catcagtgcc agcgtcttat cagccggttc cgttgcggct aacagcacat
     9301 taagaatcag tgcgagtata tccttgtccg acatcgccat gccttcatat tcagaagtac
     9361 ataggatgga aattaaatct gatcccggat tgacgcgacg ttcttcaatg accggcatca
     9421 agtattggga aagctgttcg ctgcaccata acgaatgtgc ccgcgcttca ggagattgag
     9481 agatactcgt gataaaatcg gcaactccgc tgtgccactc agagattttt tcatggtctc
     9541 ttttatccag cccgagcatg tccatcgtga cgcacaccgc aaacgtcttt ccaaaatcat
     9601 tgacgagatc aattttccct ctttcaagat agggcgctaa caagttttct gcattttgtt
     9661 taatcaatgg agacagatga tccagtgcgt caccgatgaa gcttctcact acaattcttc
     9721 ttttggcaga gtgttctttt ccatgcattt gggccagtac agggcctcgc attactggtt
     9781 cggcacgctc aacaagtgat ttcgtcgtga aaatatccgg atgctgaagg atatagcgga
     9841 catcatgata gcggctgata aaataactgt ctatcgactc ttcataatga accggatctt
     9901 cctcccgcag ttgtgaaaaa taagcatatg gattgttttg aaattgatca gaaagcacac
     9961 taaacaattt aatcgattgg ctcatgtttt actcccccta tcatccttca catgtgatcc
    10021 gtttctcaga aagcatctgc gccatttcct gtacaatgag atacccttga ttcggccgca
    10081 tacaaataga aaattcatgg ttactgatct tctcaccgag cttccacgga cgatgataag
    10141 caaggagcgt ctcttccacc tctaaaatat ccggagctcc gataaaaaac ggcagctcag
    10201 ctatgacata ttccacagcc aaattcagca tatcctcact gacttcttcc atcatcaaac
    10261 tgacgccccg tgcacgcccg attatcgctt cacgagacat gtccaaacaa gcatgtcgaa
    10321 aatgaggctg ctcaaaaaaa gcatgttcaa cttcttgtct caacagctgg taggctttgt
    10381 tatccataaa atcagaaaat gtatgaatcg ccttcggatc cccgccatga gccacaagag
    10441 ctctttctgc aaatctcctg tttcgtgata cctctttcct tacttttcgt tcagcctttc
    10501 ctctcggagt tccaagcgct tctagaagat tagcggcctc atgccccgca agtaaaacag
    10561 aaacgctttt aaattgagct ttcgcccatc caattaatct gtaaatataa tcctctgaaa
    10621 acctgctgtt aaatgggctg atccccacca aaacatgcct gcgccgttca aatatttctc
    10681 tgcagttttc cgttaatggc tcagcaataa aatgcacaga ccttctttcc gttaccattc
    10741 cggtcatctc attcacccct aaaacttatc ccgctttaag tcatcaccct caaatacaag
    10801 atggaatagc tagaacaact gaacaagacg aatggcaggc atcacttaaa gtttccaaat
    10861 gttttttaag attttaataa tcattttcaa tacccatatc atgataaatg tttactagta
    10921 aacattagtc attttatccc ttttccttcc aaacgtcaat atgatctgtg cccaaatatt
    10981 tgaaaataaa tgtaaacatc acattttcca cacacttttt acacgcatat tcagcatgac
    11041 atatcaacaa atagtctaaa caccaacaat tgacaacgaa aacaagaaaa gataaaataa
    11101 aattgttcac cagtaaacga tttgttttat tgtttcatcg taaactatta ttcctaagaa
    11161 agaaggtagc ctatgtctga tttgacaaaa cagatgatat acgacatata cgtgagactg
    11221 ctgcacctta atgaacaaaa agcgaacact tcacttcagc aattttttaa ggaggccgca
    11281 gaagaagatg tagctgaaat tcccaaaaat atgacaagca ttcacgtcat tgactgcatc
    11341 ggccagcatg aacccattaa caatgcgggg attgccagaa aaatgaactt atcgaaagcg
    11401 aatgtaacga aaatcagcac aaaactgatc aaggaagaat tcattaacag ctatcagctg
    11461 acagataaca aaaaagaagt ttattttaaa ttaacccgta aaggcagacg gattttcgac
    11521 ttacatgaga aactgcataa aaaaaaggag ctggcttttt accaattcct cgattcattt
    11581 tcacaagaag aacaaaaggc tgtattgaag tttctagagc agttgacgtc aacacttgaa
    11641 gcagaacaaa ccgatgggac tccggacaaa cctgtaaagt aaacaaaaag gcggtgtaca
    11701 ctttggctca tacaaaatca aaggcagtat tgatcttata cactgtttgc ttcagtgcat
    11761 tttttgcatc tttaagccag aacatttatt cacctattct tccgatcatt aaagaatcat
    11821 tccatgtttc cacagctatg gtgaacctgt cagtctcagt ttttatgatt gtgacagcaa
    11881 taatgcaaat tatattagga gcgatcattg attttaaagg cgctcggatc gtcttgatta
    11941 ccggtattct ggcaacggca gcagcaagca tcggctgtgc ggtgactact gactttactt
    12001 tgtttctgat attcagaatg atacaggcag ccggttccgc agcactgcct cttattgctg
    12061 ccacaacgat cggacagctg tttacaggca atgaacgcgg gagtgcaatg ggaacgtatc
    12121 aaatgctcct gtctgtcgca ccggctattg ccccagttct aggaggattc ataggcggag
    12181 cagccggata cgaagggatt ttttggatac ttgcggccat ctcgatcgtt ttgctggtga
    12241 caaacagcat cacctttcct aaagattctc caactgaatc tatgcagcaa gccaaaggca
    12301 atgtgttcgc tcattataaa tcaatattta caaatcgaac agggaacgtc attttgactt
    12361 taagttttgt tctctttttc atttattttg cagtaattgt ctacctccca atattgctga
    12421 cagagcatta ccatatagat gtgggtatag caggactgtt atatttgccg ctggcgctga
    12481 gcacgattgc aggtacgttt ctgtttaaaa gaatacaggc aaaaatcggg ctgcacacct
    12541 tgtttatcgg aagcaatgtg attgccgcct gcagcatcat tttatttgct gttacacatt
    12601 ccgtttctct cgttctcatg gctctgacgc tggcactgtt tggcatctcg atgggggtta
    12661 ttcctccctt gtactctaca atgattacta atgaatttga gcacaacaga gggagtgcaa
    12721 tcggaatgtt taactttatc cgatatacag gcatggcagc aggtccgatg gtatctgcct
    12781 acttgctcac aatgatgccg tctgccatgt cctttagcct cctaggcctt ggatttgccg
    12841 cattgagctt ttgccttctt ccgccaatgt tttcgccgca gaagcgcacg aaacaaaaaa
    12901 agcaccacat gtaaaaaagc tgcctttgcg ggcagctttt tttatttttt tctaagcggc
    12961 tctaaaatgc ctttttgaat cagcaaatgg aagaccgaca ggataacgga tgcccatatc
    13021 gctgtgccga agccgtcgat ttgaaagctg tcacccatta tggacgcggt catcataagc
    13081 gtgatggcgt taatcacaaa caagaagagt ccaagcgtca ccatggtgac cggcagtgta
    13141 aagataatta aaagcggttt aatcagcacg tttaagatcg ataaaatgag gctggcgata
    13201 atcgctgccc caatgctgct gatatggatg gagtcaatat atccatcaat gacgattaat
    13261 aacaatgcat tgactaaaat gctgactgcc cattttacca tgtcatttca tatccctttc
    13321 tgacgggacg ataaaaatcc aaatgatata aatgagcaaa accggcaaga cacttgtcat
    13381 aatggctaag atgacagtta tgactctgag gagtgatgcg tcccaattga aatattccgc
    13441 gagacctccg ataacaccgg cgattttctt atttttttct gagcgataaa gcttattcat
    13501 tcgatcacct ctgtgagtac tttagtttga tggcgcctgt tagtgattct gagaagacgg
    13561 tgatgttttg atcatgtgct tgatttgaag tgaacatcat ttctttttga atggtatcat
    13621 ttttttcctt cagcatctca acatccatta attcatggga cagcgaacca agattgcttt
    13681 tcagctctgc cttcactgcg agatcgtccg gaatcgcaag ctccacactt ccagtcgttg
    13741 tttttgcata aatggagcgg cagtctgatt ctgttacgtt aatcgcaata tttccgttaa
    13801 agctttgaac gtcaatggat tcgcttttcc ctctgagatc gatcaatccg ttaatggttt
    13861 ccgcttctat cgttccgcag ctgtggctgg cgagcttaat ttgcccgttg gccgtttcag
    13921 ctatggcttt ttcggctgtt aagtgcgaga acgacagcac gccgtttgtc gttttcgctg
    13981 agaactcttt tacatgtaaa tgttcccctc tgaccggacc gttaaacagc ttcactcgaa
    14041 tcttatcata ctccttctga ggaatataca aagtgacatt cgttttcatc gtctttttct
    14101 cagtacggat aaaaaactta tttcctttga tttcacattc aatatgctga agaaatgcga
    14161 gtctcgccgc atcctggcta tcagcgcgat ataccttcgc ctggcattcc gctctgatat
    14221 cgtcatcttc ccaaggaacg atattcacgc tgccattggc aatttgcagc tcaacactgg
    14281 aaaagtcagt atctttaaat tgaaaaatgt gctgaacatc atacgcatgg ccaaagttta
    14341 aatcaaggtc aacttccttg acctttttta cagcagaatc aatccagtca aacagcttgg
    14401 ctcctaaaga cggcttgccg ctttcttttt ttgccgttgt aaatggctct tcctcgtcat
    14461 gaacgtgaac tgagagcgct gtgattttct cttctttttc cttgtagtcg ctgtcaagct
    14521 tttcaatcag tgtcaaagct tcttgtgctg taagcttccc ttcctcaaca agcttaagga
    14581 ttcgttcctt ttcttgcttc attacgatct cctccccatt gtctacttat gctgcacgca
    14641 ggaccttaat gccctgaatc acattccaaa taataatgcc aatgacaact aagaaataaa
    14701 taaccgctcc cccgatgatt acaaatacag gaagcaagct gtctccatca atcgcaacgg
    14761 ctccgccaag taaagcaata aaaaggaaca gccagccgac aaacggaact atgtgagaaa
    14821 taagagagcg tatcgcatgg cgttttgttt ctttctcatt tacaacaaaa taagcgacaa
    14881 tcggcacaat gattggcgca ataaacacac tgaaataaca aagtgatgca ataatagctt
    14941 gattacggtt caattcattc cacactccta ttgtgaattg tccatgacaa aagatcaggg
    15001 acgttttact tatttatacg tttaaaatct cttcaggttt caaattcatt ctttagacat
    15061 gctccgattt acggaaattg gattttaaaa agttttagaa gtagaatctc ccggctatac
    15121 cgattacaat atgtaaaaag cttacggcaa ccaaggaggc tggacaagca atggagaaag
    15181 atcccagtga ctatacagta acacaagaat cagtgttaaa gctgattcat gaacaaaaaa
    15241 gaatgaatcg tgaaatgatc gccgagcttg agcagattca cggacccttc ccgatctctc
    15301 atgatatcca atatataaaa gtgctgctcg acagcagcaa cacgcatatt gttcaagatt
    15361 taatgagtgt aagtaagcag ctgtataaga agactttgta attgcgggaa catatcattc
    15421 attataactg aaacaaagct aaaggttaga tgacaatatc ttgccttttt tgttttgaaa
    15481 aaacaagtga ttccctggct gtcacaagat gattgtaaca aaaaaagcct gccggcacat
    15541 ccagttaatg gactctgtcg gcaagctgta actatcagaa agagatagcc gttcaaaatt
    15601 aacgtaacaa ttgaagcacg ttttgcggct gttggtttgc ttgagcaagc atcgcttgag
    15661 aagcttgaga aagaatgttg ttctttgtga aatcgctcat ttctttcgcc atgtcaacgt
    15721 cacggatacg agactcagca gctgttaagt tttcagaaga agcaccaagg ttgttgattg
    15781 tgtgctctag acggttttgc accgcaccaa gtttagcacg ttggtttgaa acacttgtaa
    15841 ttgcactatc gattttaaca atctcagtgt caaaactaaa atcatctgct gaaacatcga
    15901 taccttttac tcctaaagtt gttgcatcca tgttaccaat tgtgacatta atattttggc
    15961 cagcatttgc accaatttgg aatgtaaatc ctgctgtttc actaccgtct aaaagttttt
    16021 ttccgttaaa ttcagtacgt tgagaaattc catcgatctc ttcagttaaa gcatccattt
    16081 catctttaat tgcagttaaa tcttcagttt gctgtgtacc tgtgtttcct gcttgaacag
    16141 taagttcacg catacgttga aggatggcat gagtttcagt caatgcaccc tcagctgttt
    16201 ggataagaga gattccgtct tgagagtttt tagaagccat ttcaagacct ctgatttgtc
    16261 ctctcatttt ttcagaaatc gcaagacccg ctgcgtcatc tcccgcacgg ttgatgcgaa
    16321 ggcctgaaga aagtttctcc atgttttttg agctcgcact gttgtttgaa gacaaacggt
    16381 ttagtgtgtt aagcgctgca atattgtggt tgattctcat gtgaaaaata cctccatgtg
    16441 tatatgtttt tgaaatcaaa gacttccttt tctttgattt ctggcgtatc agattccaat
    16501 aaagcttcta acctatgtaa ttcagttatt gcttaaggat gcctttaagc cccttaatag
    16561 ggtttatctg cttaatttgg aaatcatcat ccgcctttca attcatatat cgacagcaat
    16621 ttgtaaatgt ttaggcgttt tcccaaagaa attttaccaa agacgaatct aaacctatta
    16681 tgccgtaaag aaaaagcttg cctgctaagc ccaaggatgg acttgctgac aagctgtccc
    16741 ctcttaacag agggttttaa gatgtagctg tttctttcgc tttcaagagc gatttcatgc
    16801 gtgttttatc acgttcgata acaggcttca aataacggcc tgtatatgat tcttccactt
    16861 cagtgatttc ctcaggcgtt cctgacgcga caatggttcc gcccccggct ccgccttccg
    16921 ggcccaaatc cacaatgtaa tcggctgtct taatgatatc aaggttgtgc tcaataacaa
    16981 gtacagtgtc tccgttgtct accaaccgtt gcagcacgac aagaagcctg gcgatatcgt
    17041 cgacatgcaa acctgtcgtt ggctcatcta aaatgtagag cgtgcgtccg gtcgagcgtt
    17101 tgtgcagctc tgacgcgagc ttcacgcgct gcgcttctcc gcctgacaag gtcgtcgccg
    17161 gctggccgag cgtaatataa cctaaaccaa catcataaag ggtttggagc ttgcgtttga
    17221 ttttcgggat attttcaaag aaagaaagag catcttcaac cgtcatatca agcacatcag
    17281 agatgctttt tcctttgtac gtcacttcaa gcgtttcacg gttatagcgt ttgccgtgac
    17341 acacctcgca tggaacgtat acgtcaggaa ggaagtgcat ttcaatttta ataatcccgt
    17401 ctccgcggca ggcttcacat cgtccgccct tcacgttgaa gctgaaacgg ccttttttat
    17461 agccgcggac cttcgcttca tttgtctgcg cgaatacatc acgaatgtca tcaaatacac
    17521 cggtgtatgt cgcagggttg gatctcggcg ttcttccaat tggcgcctgg tcaatgtcaa
    17581 tgactttgtc taaatgatcc aaacctttaa tctctttatg gctgccgggc ttcgctttcg
    17641 ctttatgaag cttttgcgcc agcgccttat gcaaaatttc attaacgagt gtactctttc
    17701 ctgaaccgga aacacctgta actgctgtaa acgtcccaag cgggaacttg gcattcactt
    17761 ttttcaggtt gttttctgaa gcacctttaa tttcaatgta acgtccgtcc ggctttcttc
    17821 tttcaggagg caatgggata aactttttcc ctgataaata gctgcccgtt aatgagtttg
    17881 gatcttccat cacttcttcc ggcgtacccg cagatatcac ctgtccgccg tgaatgccgg
    17941 ctcccggtcc aatatctatt aaataatctg ctgccatcat cgtgtcctca tcatgttcga
    18001 caacaatcag cgtgttcccg aggtctctca tatttttcag agcgctgatc aagcggtcgt
    18061 tatcacgctg atgcagaccg atagacggct catctaaaat ataaagcaca ccggataaac
    18121 gcgagccaat ttgagtcgcc agcctgatgc gctgtgcctc tcccccggac aatgtacccg
    18181 ctgccctgct caatgtcagg taatcgaggc cgactttgtc cagaaagctt aagcgctcca
    18241 caatttcgcg caaaatcaaa ttggcgatct gcatatcctt ctcagaaagg gtaaggtctt
    18301 taaagaaggc aagtgcgtcg gcgacagaca gctcggtaat ttttccaatg tggcggccgt
    18361 caatcagtac ggcaagcgcc tctttcttta accgatagcc tttgcacgtc ggacaagact
    18421 tctgagacat atactgctcc atttgctcac gtatgaaatc ggagcctgtc tccttatagc
    18481 gtctttcaat gttgcgcaat acgccttcaa attgaatttc accttcgcgg atttgtccaa
    18541 aatcattttc atatcggaaa taaatcaggt catctccgct gccgtatagc actttatcca
    18601 gttgatgctt cggcaaatct ttgaccggca catccatatc aatcccgtag tgggtgcaga
    18661 ctgcctcaag cagctgagga taatattgtg agctgatcgg tgtccaaggg gcgaccgcat
    18721 tctccttcaa tgacaaatct tgattgggaa tgacaagatc ggcatccact tcaagcttca
    18781 ttccgagacc gtcacacgtc ggacacgccc cgaacggact gttaaacgaa aacagacgcg
    18841 gctcaagctc accaattgaa aatccgcagt gcggacaggc atgatgctcg ctgaacatca
    18901 gctcttcctc accgatgaca tcgatcataa cccgtccttc acctaaacgg agcgccgttt
    18961 ccaatgaatc agacagccgg gctgccacgc cttctttcac gacaatccgg tcaatgacta
    19021 cctcaatgga atgcttcttg ttcttttcta attcgatatc gtcggaaagc tcagccatct
    19081 cgccgtcaat tctgactctg acatagcctt gttttctaat ctgttcaagc actttgacat
    19141 gagcgccttt tcggcccgag acaatcggcg ccagcacctg aagcttcgtc cgttccgggt
    19201 attccagaat tctgtccacc atttgctcga tggtctggga tgtaatctca attccgtgct
    19261 ccggacaatg aggcttccct actctcgcat ataaaagacg cagataatca taaatctcag
    19321 ttaccgtacc gacagtagac ctcggattac ggcttgttgt tttctgatca atgctgatgg
    19381 cgggagagag cccctcaatt gcatccacat caggcttatc catttgccct aaaaactggc
    19441 gggcataagc agacagcgac tcgacatacc gtctctgtcc ttcagcatat atcgtgtcaa
    19501 aggcaaggga ggatttacct gatccggaca aacccgtgac aacgacaagc tgatctctcg
    19561 gaatcgttac atctatattt ttcaggttat gcgccctggc tcccttcacc tctatccgat
    19621 ccatagccat ttgttcatca tccttccgct tttagctcta aaagtaaatc gcgaagctcc
    19681 gcggctctct caaagtcaag cgccttggcg gcttccttca tttcatgctc catctgttca
    19741 acgactttct ggcgttcttt cttcgtcatt ttcgacagct tcggcgcggc ttttgttttg
    19801 tattccgctt tatcctcagc tgctactgtg gcacgaatga catcgcgaat ttctttattt
    19861 atcgttttcg gcgtaatgcc gtgctcttca ttaaaccgct cctgctgctc gcggcggcgt
    19921 tttgtttcat taatcgcaat ttccatagac ttcgttattt tatcggcgta cataatgacg
    19981 cggccttccg catttctcgc tgcccgtccg atggtctgga tcagcgaccg ctccgaacga
    20041 aggaaacctt ccttatccgc atccaaaatc gcaacaaggg atacttcggg aatgtccaaa
    20101 ccttccctca gcaggttgat gccgacaagc acatcgtact tgccaaggcg caggtcgcgg
    20161 ataatttcaa tccgttcaag cgtcttgatt tcagaatgca gatagtttac tttaatgccg
    20221 atttccttta aataatcggt cagatcctct gacatcttct tcgtcaaagt tgtcacaagc
    20281 acccgttcat ttcgctcgat tcttgcttga atttcgccga tcaagtcgtc aatctgacct
    20341 tcgattggac ggacgtcaat aagcgggtca agaagccccg tcggacgaat gatctgttcg
    20401 accatttcat ctgtatgttc aatctcgtac ggccctggtg ttgctgatac atacacgata
    20461 ttgtgcatat gcttttcaaa ttcctcaaaa cgaagcggac ggttatcaag cgctgatgga
    20521 agccggaagc cgtgatccac gagcacctgt ttccgcgcct ggtctccgtt aaacatgccg
    20581 cgcacctggg gaattgtcac atgcgactca tccaccacga tcataaaatc gtctgggaaa
    20641 taatcaagaa gcgtatacgg cgttgaacct ggaggccgca gagtcaaatg tcttgaatag
    20701 ttctcgatgc cggagcagaa acccatttca cgcatcattt caagatc
//
