LOCUS       NZ_CP090423            20879 bp    DNA     circular CON 08-MAY-2024
DEFINITION  Stenotrophomonas maltophilia strain GYH chromosome, complete genome.
ACCESSION   NZ_CP090423
VERSION     NZ_CP090423.1
KEYWORDS    RefSeq.
SOURCE      Stenotrophomonas maltophilia
  ORGANISM  Stenotrophomonas maltophilia
            Bacteria; Pseudomonadota; Gammaproteobacteria; Lysobacterales;
            Lysobacteraceae; Stenotrophomonas; Stenotrophomonas maltophilia
            group.
REFERENCE   1  (bases 1 to 4791742)
  AUTHORS   Cheng,Z., Zhao,P., Chen,J., Zhao,J., Yu,J., Zhang,S. and Guan,Y.
  TITLE     Aerobic biodegradation of trichloromethane by Stenotrophomonas
            maltophilia GYH: Biodegradation characterization, genome functional
            analysis and metabolic pathway determination
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 4791742)
  AUTHORS   Cheng,Z., Zhao,P., Chen,J., Zhao,J., Yu,J., Zhang,S. and Guan,Y.
  TITLE     Direct Submission
  JOURNAL   Submitted (28-DEC-2021) college of environment, Zhejiang university
            of technology, 18 Chaowang RD, Xiacheng District, HangZhou, Zhejiang
            313200, China
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: Canu v. v1.5
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 27.0x
            Sequencing Technology             :: Oxford Nanopore
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_023518235.1-RS_2024_05_06
            Annotation Date                   :: 05/06/2024 14:53:59
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 4,547
            CDSs (total)                      :: 4,455
            Genes (coding)                    :: 4,428
            CDSs (with protein)               :: 4,428
            Genes (RNA)                       :: 92
            rRNAs                             :: 5, 4, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 5, 4, 4 (5S, 16S, 23S)
            tRNAs                             :: 75
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 27
            CDSs (without protein)            :: 27
            Pseudo Genes (ambiguous residues) :: 0 of 27
            Pseudo Genes (frameshifted)       :: 8 of 27
            Pseudo Genes (incomplete)         :: 22 of 27
            Pseudo Genes (internal stop)      :: 0 of 27
            Pseudo Genes (multiple problems)  :: 3 of 27
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 12:15:52
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 4673562
            Orig. end                         :: 4694441
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP090423.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            Bacteria and source DNA available from Zhejiang university of
            technology.
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..20879
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene-precursor"
                     /region_number="5"
                     /rules="(PT_FPPS_like and not PT_HPP)"
                     /tool="antismash"
     cand_cluster    1..20879
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_FPPS_like and not PT_HPP)"
                     /kind="single"
                     /product="terpene-precursor"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..20879
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:10879](-)"
                     /cutoff="10000"
                     /detection_rule="(PT_FPPS_like and not PT_HPP)"
                     /neighbourhood="10000"
                     /product="terpene-precursor"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..10879)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="(PT_FPPS_like and not PT_HPP)"
                     /neighbourhood="10000"
                     /product="terpene-precursor"
                     /protocluster_number="1"
     gene            521..2008
                     /gene="rng"
                     /locus_tag="LZ605_RS21670"
                     /old_locus_tag="LZ605_21670"
     CDS             521..2008
                     /EC_number="3.1.26.-"
                     /GO_function="GO:0003723 - RNA binding [Evidence IEA]"
                     /GO_function="GO:0004540 - RNA nuclease activity [Evidence
                     IEA]"
                     /GO_process="GO:0006396 - RNA processing [Evidence IEA]"
                     /codon_start=1
                     /gene="rng"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002802933.1"
                     /locus_tag="LZ605_RS21670"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LZ605_21670"
                     /product="ribonuclease G"
                     /protein_id="WP_107231116.1"
                     /transl_table=11
                     /translation="MSEEILVNVTPRETRVAVIENGMLQELHIERGWRRGVVGNIYRGK
                     VQRVMPGMQAAFVEVGLERAAFLHANDVVRPAPVASADTENTTLPPPASVPIVELLRDG
                     QDIVVQVVKDPIGTKGARLTTQISIPSRYMVLLPQSKVVGVSARIEDETERARLKALVT
                     ELSAQHGGYGYIVRTNAEGQPAEAIAEDIAYLSRVWNVVERRGREAPPCSIIYEDLSLP
                     LRSVRDLIRKDVDKVKVDSKETFAQLQAFVAKYMPVLAEKIELYSGDRPIFDMFGVEDE
                     IGRALDKQVPLKSGGYLVIDQTEAMTTIDVNTGSFLGQRNLEETVFRTNLEAAQAVARQ
                     LRLRNLGGIIIIDFIDMDDAEHRRQVLRTLEKALARDHAKTTVYDFSPLGLVEMTRKRT
                     VESLERQLSETCPQCSGRGSIKTTETVTYEIFREITRAVRQFDAARLLVIASSKVVARI
                     TDEESSAVAELEEFLGKSIRFQADEQYLQEQFDVVLL"
     gene            2039..5896
                     /locus_tag="LZ605_RS21675"
                     /old_locus_tag="LZ605_21675"
     CDS             2039..5896
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014647937.1"
                     /locus_tag="LZ605_RS21675"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LZ605_21675"
                     /product="YhdP family protein"
                     /protein_id="WP_249843290.1"
                     /transl_table=11
                     /translation="MSAPPRLRLRRIRRHFIAACAVGLVGLALLVGTLSQLLPLAERHP
                     GTIAAWLSERAGQPVRFDQLQTAWTRRGPLLQLKGLRIGAGQGLAIGEAEVLVSMYSGL
                     LPGRSLTELRLRGLALDLQQGQDGRWSVRGLPQSSSGGDPLDALRRLGELQVIEGRLGV
                     HAPQLGIDATLPRIDLRLRVNGDRLRVGVRAWAQADALPLTAVLDVDRRHGNGQAWLGA
                     DPVDFHAWSPLLAAGGVRLREGKGELNLWLTLRDFAPVALTTDSDLRGVRVQGAAMPGV
                     AAPQLQLQRVQARLRWQRQAEGWALQVPRLRLTTDEGEQRLDGLQVQVGRQLRVSAAAA
                     QAGTALRGLALSDRLPADLRRWLFLSRPQLEVAELQLAGERDGPLWAQGELQSLGFASV
                     GGSPGVRGLGGRFEGDANGFSLQLQPQRQLQFDWPTGFGVRHDLHLAGQVVGWRDEGGG
                     WRIGTPAMRVEGTDYAADVRGGVWFQGDGTRPWLQLAAKLDDVPMTAAKRFWIHSKMSK
                     GATDWLDMALAGGQVRGGVGLVTGDLDDWPFDNHDGRFEATGHITQGEIRFQHDWPLMS
                     QVDADIAFIGPGFDMRGRGDLAGVAVQTFEAGIADFGQQPLYVRADAQSEAGKLLAMLR
                     QSPLHKDYGDTLDNLTAAGPAHVTFDLLQPLHHDEGGGHLQGTVDLAGVKLVDKRFQLA
                     FDNMHGQARYSNGGFDAEELSVRHLGQDGRLSLRAGGYVRDSRLAFESQLSAHLDAGVL
                     IDRAPEMAWLKPYINGTSAWTIAVNLPKVAPGAPAPPSELRLSSDLVGTRLDLPAPLDK
                     PATEPLATSVAAQLPMGAGRIDVAFGQRLALAARSHNNQTGVQVTLGSDRVDREPPPNG
                     LTVNGRSPTLDALEWIGLARGGSDDDAMPLRAVDVQVGQLKLIGGVFEQTRLQLRPGAQ
                     ALDVRLDGPSLAGRLTVPNAEGGTISGQLDRVHWQSLPAAPGATPAPARVQAGANDMDP
                     AKLPPFALDIADLKFGKVVLGQAVLRTRPLANGLNVDELRFRAPDQEIDISGRWLGRSG
                     GARTELTAQVRSEDLGGLMQNLDYGGQLRGGAGQAQLQASWSGGPSDFQLANLQGSLDL
                     HARNGQLLELEPGAGRVLGLLSVTQLPRRLMFDFRDFFSKGFAFNQIDGRMQFGQGMAR
                     TDKVLIEGPAANITIRGQADLRNQQFDQTIDVNPRAGNLLTVVGAVAGGPVGAALGAAT
                     NAVLSKPLGEIGARTYKVTGPWKEPKVEVIERSRDKTPPAPGPAPAPAIPPTVTDLPRS
                     R"
     gene            5954..7399
                     /gene="tldD"
                     /locus_tag="LZ605_RS21680"
                     /old_locus_tag="LZ605_21680"
     CDS             5954..7399
                     /EC_number="3.4.24.-"
                     /GO_function="GO:0008237 - metallopeptidase activity
                     [Evidence IEA]"
                     /GO_process="GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /gene="tldD"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007972594.1"
                     /locus_tag="LZ605_RS21680"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LZ605_21680"
                     /product="metalloprotease TldD"
                     /protein_id="WP_249843291.1"
                     /transl_table=11
                     /translation="MTDIALTLAQDRLLRPGGLDTAGLERAFGQLLGPGVDFGDLYFQH
                     ARRESWSVEDGIVKDGAHSIEQGVGVRAIAGEKTGFAYSDDIHADALLTAAQSARAISR
                     EGGAQSGRSLLRGTARALYPALDPIDGIGNEAKVEVLKRLDGYLRAADPRVKQVMVSLS
                     GGVDTVLIARSDGVLGADVRPLVRLNVQVIVEHNGRRESGYSGGGGRFGYDELFAGGRP
                     EALAREALRQALVNLEAVPAPAGVMPVVLGPGWPGVLLHEAVGHGLEGDFNRKGTSVYA
                     GRIGERVAAPGVTIVDDGTLDGRRGSLNIDDEGHPTQCTTLIEDGILVGYMQDSLNARL
                     MGMAPTGNARRESFAHLTMPRMTNTYMRAGQHDPQEMIRSVKKGLYAVNFGGGQVDITS
                     GKYVFSATEAYLIEDGRITAPVKGATLIGNGPETMQKVRMIGNDLALDEGVGVCGKDGQ
                     SVPVGVGQPSLLIEGITVGGTQA"
     gene            complement(7441..8028)
                     /gene="yjgA"
                     /locus_tag="LZ605_RS21685"
                     /old_locus_tag="LZ605_21685"
     CDS             complement(7441..8028)
                     /GO_process="GO:0042254 - ribosome biogenesis [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="yjgA"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012511756.1"
                     /locus_tag="LZ605_RS21685"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LZ605_21685"
                     /product="ribosome biogenesis factor YjgA"
                     /protein_id="WP_249843292.1"
                     /transl_table=11
                     /translation="MRGRDEETGEFLDKSRKQKRGEALEVLALGEKLVSLTPAQLARLP
                     IPEDLLPHIAECKRITAHIAHKRQLAFLAKHMRREDEATLEAIRDALDANSETGRREVA
                     MMHRVEDWRERLLADGDTALAALLDDYPQADRQQLRTLVRNAQAEKARNKPPRAYREIY
                     QVLRGLMLPAALGLKTASGDDADDTVDDADTD"
     misc_feature    8039..8052
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 17.47"
                     /tool="antismash"
     misc_feature    complement(8044..8053)
                     /note="TFBS match to ToxT, Regulator of MSHA biosynthesis,
                     confidence: weak, score: 14.42"
                     /tool="antismash"
     gene            8097..9464
                     /gene="pmbA"
                     /locus_tag="LZ605_RS21690"
                     /old_locus_tag="LZ605_21690"
     CDS             8097..9464
                     /EC_number="3.4.24.-"
                     /GO_function="GO:0008237 - metallopeptidase activity
                     [Evidence IEA]"
                     /GO_process="GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /gene="pmbA"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019662101.1"
                     /locus_tag="LZ605_RS21690"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LZ605_21690"
                     /product="metalloprotease PmbA"
                     /protein_id="WP_249843293.1"
                     /transl_table=11
                     /translation="MNVIAPEVAVGDDSPARLERLADLSQQLLDRARALGASQAEVSCS
                     EDRGLDVNVRLGEVETVQSTRDRGIAVTVYFGQRKGSASTGDLNESSLAATVEQACAIA
                     RHTEDDPAAGLAEAALMATHFPELDSWHPWALQADEAVDLALACENAGREADAQIRNSD
                     GASVSSMQSLSVYANSHGFIGRERGTHHSIGCALIAGQGDGMQRDGWYTSALAREDLED
                     VGRVGRQAAERTVARLQPRSLATGSMPVLFAPEVARSLVGHLLTAVSGGALYRQASFLL
                     DSVGQRLFPEWMQIDELPHLRRGLRSAAFDGDGVATRASALVRDGVLQRYVLGSYSARK
                     LGLQTTANAGGVHNLQLAANAGSLHEIAARMGSGLLVTELMGQGVNGVTGDYSRGAGGF
                     RVENGEIQYPVDGITIAGNLREMFSSIEAVGSDVDPRSHIRTGSILLGRMTIAGND"
     gene            9552..9923
                     /locus_tag="LZ605_RS21695"
                     /old_locus_tag="LZ605_21695"
     CDS             9552..9923
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014647933.1"
                     /locus_tag="LZ605_RS21695"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LZ605_21695"
                     /product="DUF4870 domain-containing protein"
                     /protein_id="WP_040007321.1"
                     /transl_table=11
                     /translation="MSEFDNVPPPPATTNAPADQRTMALAAHLLGIFTWFIGPLIIWLI
                     NKDDASKAFVTDQAKEALNFQITITIAMLICIVLTIVIIGGILAPIVGILNLVFCIIAA
                     VKANNGEAYRYPFALRLVK"
     gene            complement(10001..10879)
                     /locus_tag="LZ605_RS21700"
                     /old_locus_tag="LZ605_21700"
     CDS             complement(10001..10879)
                     /EC_number="2.5.1.10"
                     /GO_function="GO:0004337 - geranyltranstransferase activity
                     [Evidence IEA]"
                     /GO_process="GO:0008299 - isoprenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene-precursor: PT_FPPS_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1182: Polyprenyl synthetase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008264747.1"
                     /locus_tag="LZ605_RS21700"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LZ605_21700"
                     /product="farnesyl diphosphate synthase"
                     /protein_id="WP_249843294.1"
                     /sec_met_domain="PT_FPPS_like (E-value: 4.6e-66, bitscore:
                     220.8, seeds: 145, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTAELLFARWRDRIESQLDAALPSPAEAPQRLHQAMRYSVLGGGK
                     RMRPLLVYASGQLFGAQAETLDAAAMAVELIHAYSLVHDDLPAMDDDALRRGKPTTHIA
                     FDEATAILAGDALQTRAFGLLADAPLPATLRVACLQTLAHASGASGMCGGQALDIDATG
                     QQQSLAALTRMHALKTGALIRAAVRMGALCGQAHEPQLAQLDHFADALGLAFQVRDDIL
                     DVEASSEQLGKTAGKDQAQDKSTFPALLGMDGAKAQLRELAARMQSSLAGYGEEGDALR
                     ALATLAVERDH"
     gene            complement(10869..11129)
                     /locus_tag="LZ605_RS21705"
                     /old_locus_tag="LZ605_21705"
     CDS             complement(10869..11129)
                     /EC_number="3.1.11.6"
                     /GO_component="GO:0009318 - exodeoxyribonuclease VII
                     complex [Evidence IEA]"
                     /GO_function="GO:0008855 - exodeoxyribonuclease VII
                     activity [Evidence IEA]"
                     /GO_process="GO:0006308 - DNA catabolic process [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005410522.1"
                     /locus_tag="LZ605_RS21705"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LZ605_21705"
                     /product="exodeoxyribonuclease VII small subunit"
                     /protein_id="WP_188240762.1"
                     /transl_table=11
                     /translation="MAKKSPENASPVAQFEQSLESLEQLVEQMETGELSLEASLSAYER
                     GVGLYRQCQQALEQAELRVRLLSDPAQPETSEPFDPPSHDG"
     gene            complement(11166..12452)
                     /gene="tilS"
                     /locus_tag="LZ605_RS21710"
                     /old_locus_tag="LZ605_21710"
     CDS             complement(11166..12452)
                     /EC_number="6.3.4.19"
                     /GO_function="GO:0016879 - ligase activity, forming
                     carbon-nitrogen bonds [Evidence IEA]"
                     /GO_process="GO:0006400 - tRNA modification [Evidence IEA]"
                     /codon_start=1
                     /gene="tilS"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005418067.1"
                     /locus_tag="LZ605_RS21710"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LZ605_21710"
                     /product="tRNA lysidine(34) synthetase TilS"
                     /protein_id="WP_249843295.1"
                     /transl_table=11
                     /translation="MTAFPALVPLDAPLLVGYSGGVDSTVLLHWLWRCAQASATPLRAV
                     HVHHGLQPAADDWVRHCQQQCAALGMELAVHRVQVDLHPGLGLEGAARQARRAAFAAEL
                     RDGETLALAQHQDDQAETFLLRALRGSGVDGLAAMAEHNQLGAHRLWRPLLHAPRGALL
                     DYARQHALCWIEDPSNSEDHADRNFLRLHVLPLLRQRWAHAAAALAGSATHCRQTRELL
                     DEEDAELIAHLEVAPRVLSLQLLRQVSPGRAARVLRAWVLGHGAPPLPATVLQQALEQL
                     LPAANDRQAQVRWHDHAIRQWRDHAYLLPARLPALPADWQATWDGRAPLPLPDGGQLRL
                     RGASAFEQPLQIRARVGGERILMPGRQHAHALKDCLQREHLAPWRRAQLPLLFADGQLL
                     AAADVVISAPLQAWLLARDAQLQWRPGGW"
     gene            complement(13010..13555)
                     /locus_tag="LZ605_RS21715"
                     /old_locus_tag="LZ605_21715"
     CDS             complement(13010..13555)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019660636.1"
                     /locus_tag="LZ605_RS21715"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LZ605_21715"
                     /product="WG repeat-containing protein"
                     /protein_id="WP_249843296.1"
                     /transl_table=11
                     /translation="MTLRQARPARAGGRFARSLALFGMLASANALAQAPACKLLTDEHG
                     LWPLPNCEVVDHRPKIQPGTLQDLNFDDHGLAVVYADQGFHYVDRTGRSLPVLTWDNGP
                     ETPEEGLLRGRVGNRVGYFDLTFRQVVPGTFDFAWPFRDGVAEVCNGCRRGTPDGDGHT
                     PMEGGEWFRIDRTGRRLK"
     gene            complement(13552..15258)
                     /locus_tag="LZ605_RS21720"
                     /old_locus_tag="LZ605_21720"
     CDS             complement(13552..15258)
                     /EC_number="3.1.3.1"
                     /GO_function="GO:0016791 - phosphatase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019660635.1"
                     /locus_tag="LZ605_RS21720"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LZ605_21720"
                     /product="alkaline phosphatase"
                     /protein_id="WP_249843297.1"
                     /transl_table=11
                     /translation="MRRSVSLLAACATTLLLGACASTTPASAPAGLKVAVDPVAHPAGE
                     TPQWWYRSGAAQAAANGAMAGKAKNVILFLGDGMSLTTVAASRIYEGQRKGGSGEENLL
                     SWERFPATAFSKTYNTDSQTPDSAGTMTAITTGVKTHMGAIGVSAGSRTDCADSLSKGL
                     LTWLQLADSAGLATGVVSTARLTHATPAATYAHSPERNWENDTDLTDAAKAAGCKDIAQ
                     QLLSTSRYGRGPLVALGGGRGEFTTVEERDPEYDDKVGQRLDGRSLVQEWQQAHPQGAY
                     VWNSKQLAAAANAPAILGLFEPDHMRYEHERPQDPGGEPSLAELTAAAIKNLSQHPEGY
                     VLMIEGARIDHANHSGNAYRALTETVALSDAVRVANELTSADDTLIIVTADHSHTLNFV
                     GYPARGNPILGKVKDKGGEDGAGKLDYALDGTGQPYTTLSYANGPGHTGSSNQQPAGPK
                     RYPHNPSSFEPANGRPNLREVDTEHPDYMQEALVPMKSESHGGEDVGIWARGPGSKAIR
                     GTLEQNAIYHMIVQATPALRERLCQAGTCDDKGVPVQLPAPTAFERKAEDK"
     gene            15413..16747
                     /locus_tag="LZ605_RS21725"
                     /old_locus_tag="LZ605_21725"
     CDS             15413..16747
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1212:
                     sodium:dicarboxylate symporter"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014038012.1"
                     /locus_tag="LZ605_RS21725"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LZ605_21725"
                     /product="dicarboxylate/amino acid:cation symporter"
                     /protein_id="WP_107231107.1"
                     /transl_table=11
                     /translation="MKLVSAWLRIPFWQRVVGGFVLGALAGWALGPAAETWFGPLGELY
                     VTLIKMIAVPLVFFAVINAISSLHGQKSVAALSGRTFLWFVITAALAVCVGLAVGTVLQ
                     PGAGGLQLSMASNYVPREVPSVVQVLLDVVPANVFYALSGIGTKVNAAGETVLAAGRGS
                     ILPVIFFAGLVGFAIVKLGEKVTEARKLVGQMSDIMIQVTRFVLEVTPIGTFGLIAGLV
                     GSYGFEKLLPLGHFVLALYVACALHIVVVYSALLMAHGLNPLKFFRGAAPGMQVAFVSS
                     SSFAAMPVALRSITHNLGVNKDYGSFAVPLGASIKMDGCGAIYPALCAVFIAQYSGVPL
                     TPEQYVVVLIASVLGSFGTAGVPGTAVIMATVVLSAANLPLETIGYLYAIDRILDMMRT
                     MTNVTGQMLVPVIVAKETGLLDQAVYDNPSSNVGVDDPDPTPPRG"
     gene            complement(17057..17767)
                     /locus_tag="LZ605_RS21730"
                     /old_locus_tag="LZ605_21730"
     CDS             complement(17057..17767)
                     /GO_function="GO:0008233 - peptidase activity [Evidence
                     IEA]"
                     /GO_function="GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /GO_process="GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003475603.1"
                     /locus_tag="LZ605_RS21730"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LZ605_21730"
                     /product="C40 family peptidase"
                     /protein_id="WP_229302309.1"
                     /transl_table=11
                     /translation="MLGLALCLTSLPAWSQTAPNRSSDVTPAPVAESTARPAAKAEAAA
                     PQRSRVDAAASATLAALLPHLAANDTIPLMDRSAVVAGDLSRLLANYDTSSAANGSVVG
                     TAADNGKVQSLLRRAMTLLGTPYRWGGSNPDSGFDCSGLVGYVFRSALGIELPRVSREM
                     AHDDNAELINDRTALAAGDLVFFGRKGRVDHVGIYVGDGRFLHAPSSGKDVRVDTLLSG
                     YWGNKFMQARRVDL"
     misc_feature    17829..17844
                     /note="TFBS match to AfsQ1, Two-component system AfsQ1-Q2,
                     activator of antibiotic production, confidence: strong,
                     score: 19.52"
                     /tool="antismash"
     misc_feature    complement(17847..17856)
                     /note="TFBS match to ToxT, Regulator of MSHA biosynthesis,
                     confidence: weak, score: 14.63"
                     /tool="antismash"
     misc_feature    complement(17924..17939)
                     /note="TFBS match to CRP, Cyclic AMP receptor protein,
                     confidence: medium, score: 17.4"
                     /tool="antismash"
     misc_feature    17939..17952
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 16.45"
                     /tool="antismash"
     gene            complement(17965..18504)
                     /locus_tag="LZ605_RS21735"
                     /old_locus_tag="LZ605_21735"
     CDS             complement(17965..18504)
                     /GO_function="GO:0008233 - peptidase activity [Evidence
                     IEA]"
                     /GO_function="GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /GO_process="GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014038010.1"
                     /locus_tag="LZ605_RS21735"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LZ605_21735"
                     /product="C40 family peptidase"
                     /protein_id="WP_249843298.1"
                     /transl_table=11
                     /translation="MHITPVSSGPRRLLTPALLLALPLLLTACGGGKATRPAPPPPTAH
                     WPKTVPDNPEAANSVLMRAISLVGTPYRYGGNTPDSGFDCSGLVAYVYREMLDLKLPRT
                     SRDLAAVQGPKIDPQRLATGDLVFFGSRGNVTHVGIYVGEGRFVHAPSTGGTVRLDSLS
                     GPYWKDHYTGAKRVLR"
     gene            18616..19098
                     /locus_tag="LZ605_RS21740"
                     /old_locus_tag="LZ605_21740"
     CDS             18616..19098
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005418041.1"
                     /locus_tag="LZ605_RS21740"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LZ605_21740"
                     /product="peptidylprolyl isomerase"
                     /protein_id="WP_107231105.1"
                     /transl_table=11
                     /translation="MKIEKDRVVRFHYTVSEAGQEPIESSKDRGEPLAILIGHGNIIPG
                     LENAMMDKEAGATFSVDVKAADAYGERREGLSQRVPKKHFGNTKLAPGQQVVLQTNFGP
                     RAVTVQKVGMSVVDVDLNHPMAGKDLHFDVEIVDVREAGKEEIDHGHVHGDGGHQH"
     gene            19198..20442
                     /locus_tag="LZ605_RS21745"
                     /old_locus_tag="LZ605_21745"
     CDS             19198..20442
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005410514.1"
                     /locus_tag="LZ605_RS21745"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LZ605_21745"
                     /product="DUF418 domain-containing protein"
                     /protein_id="WP_249843299.1"
                     /transl_table=11
                     /translation="MVDLLDGRPVNAASPSLQPLASSERIAVLDVLRGAALLGILLMNI
                     EAFSGPLDLAFTGIDTHWQGLDYWADAFVYVFVQGKFFTLFSLLFGAGFAVMAQRAEVA
                     GRAFTPFYLRRSAGLLLIGLCHALLVWSGDILVLYALVSLPLLACREAPRSWLPWMGVI
                     VYLGGVAMMLLVGAMVSMAPVEDLQKMLADAQQEIAQQRLVYGQGSWMQANAQRLGEFG
                     SSMGALLITGPEVLGMFLIGSWFAGSGALATPERFVRLYAVLRWVALPLGLVITLLGVV
                     WKPYLAPGAYDLPVTAAMALVTVGGLPMCLGYLAWIVHWRTRLAWLAPVGRMALTHYLG
                     QSLLCTWLFYHYGLGAFGQMPRSMQLLFALALFAVQVGISHAWLRRFRFGPMEWLWRAM
                     TYRQWPPMRRGAGQG"
ORIGIN
        1 gaggtcgtcg agcagcgcgc ggcgactgaa agcgccgaac actatgtctg ccgggtcgcc
       61 gccgacaagg cgcgtgccgg gctggcgcgg gtgcgggctg acgacccgca ggcgcgggtg
      121 ctgggctcgg acaccgaagt ggtgctggac ggtgaagtgt tcggcaagcc ggccgatgcg
      181 gccgatgcgc gcgcgatgct ggcacgcctg gccggccgta cccaccaggt gatgacggca
      241 gtggtggtgg tcggcgccga cggcgaggac accgagctgg tcatttccga ggtgaccttc
      301 gccccgatcg ctgcggccga catcgccgcc tacgtggcca ccggcgaacc gctggacaag
      361 gccggcgcct acgccatcca gggcggggcc gagcgctgga tcgaacacct ttccggcagc
      421 tactccggcg tgatggggct gccgctgctg cacaccgatc gtctgctggc acgttgcggc
      481 gtgccggctc ctactgccga tgccgccagg gaggctgccg atgtctgaag aaatcctggt
      541 caatgtgacc ccgcgcgaga cccgggtcgc ggtgatcgaa aatggcatgc tgcaggaact
      601 gcacatcgag cgcggctggc gccgtggcgt ggtcggcaac atctaccggg gcaaggtgca
      661 gcgggtcatg cccggcatgc aggcggcttt cgtcgaagtc gggttggaac gcgcggcgtt
      721 cctgcacgcc aacgatgtgg tgcgtccggc accggtggcc agtgccgata ccgagaacac
      781 caccctgccg ccgccggcca gcgtgccgat cgtcgagctg ctgcgcgacg gccaggacat
      841 cgtggtgcag gtggtgaagg acccgatcgg caccaagggc gcgcggctga ccacgcagat
      901 cagcattccc tcgcgctaca tggtgctgct gccgcagtcg aaggtggtgg gggtgtcggc
      961 gcgcatcgag gatgaaaccg aacgcgcgcg gctgaaggcg ctggtgaccg aactgtcggc
     1021 acagcacggt ggctacggct acatcgtgcg caccaatgcc gaaggccagc cggccgaggc
     1081 catcgccgag gacatcgcct acctgtcgcg ggtatggaac gtggtcgagc gccgcggccg
     1141 cgaagcgccg ccgtgcagca tcatctatga agacctgagc ctgccgctgc gttcggtacg
     1201 cgacctgatc cgcaaggacg tggacaaggt gaaggtcgac tcgaaggaga ccttcgccca
     1261 gctgcaggcc ttcgttgcca agtacatgcc ggtgctggcc gagaagatcg agctgtattc
     1321 cggcgaccgc ccgatcttcg acatgttcgg cgtggaagac gagatcggcc gcgcgctgga
     1381 caagcaggta ccgctgaagt ccggcggcta cctggtgatc gaccagaccg aggcgatgac
     1441 caccatcgat gtgaacaccg gttcgttcct cggccagcgc aatctggaag agacggtgtt
     1501 ccgcaccaac ctggaagcgg cacaggcggt ggcccgacag ctgcgcctgc gcaacctggg
     1561 cggcatcatc atcatcgact tcatcgacat ggacgatgcc gagcatcgcc gccaggtgct
     1621 gcgtaccctg gaaaaggcgc tggcccgcga ccatgccaag accacggttt atgacttctc
     1681 gccgttgggc ctggtggaga tgacgcgcaa gcgcacggtc gaaagcctgg agcgccagct
     1741 gtcggaaacc tgcccgcagt gcagcggccg tggcagcatc aagaccaccg agacggtcac
     1801 ctacgagatc ttccgcgaga tcacccgtgc ggtgcgccag ttcgatgcgg cgcgcctgct
     1861 ggtgatcgct tcgagcaaag tggtcgcgcg catcaccgac gaggaatcct cggcggtggc
     1921 cgagctggag gaattcctcg gcaagagcat ccgcttccag gcggacgagc agtacctgca
     1981 ggagcagttc gatgtcgttc tgctctgatc ctcgccggct gcaggccggc ggtggccgat
     2041 gagcgcgcca ccgcgcctgc gactgcgaag gatccgccgt catttcattg ccgcctgtgc
     2101 ggtgggcctg gttgggcttg cactgctggt gggcacgctc agccagctgt tgccgctggc
     2161 cgagcgtcat cccgggacga ttgccgcctg gctgagcgag cgtgccggcc agccggtgcg
     2221 ttttgaccag ctgcagaccg cctggacccg gcgcggcccg ctgctgcagc tgaagggcct
     2281 gcgcatcggc gccggccagg gcctggccat cggcgaggcc gaggtgctgg tgtcgatgta
     2341 cagcgggctg ctgcccgggc gttcgctgac cgagctgcgc ctgcgtggcc tggcgttgga
     2401 cctgcaacag ggccaggacg gtcgctggtc ggtgcgtggg ctgccgcagt ccagcagcgg
     2461 gggggacccg ctggatgcac tgcgccggct cggcgaactg caggtgatcg agggccgcct
     2521 gggcgtgcac gcgccgcagc tgggcatcga tgccaccttg ccgcgcatcg acctgcgcct
     2581 gcgggtcaat ggcgaccgcc tgcgggtagg cgtacgtgcg tgggcgcagg cggacgcgct
     2641 gccgctgacc gcggtgctgg acgtggaccg ccgccatggc aacggccagg cctggctggg
     2701 tgccgatcct gttgatttcc atgcctggtc gccactgctg gcggccggcg gcgtgcgcct
     2761 gcgtgaaggc aagggcgaat tgaacctgtg gctgaccctg cgcgacttcg cgccggtggc
     2821 gctgaccacc gactcggacc tgcgcggggt gcgcgtgcag ggcgctgcga tgcccggcgt
     2881 ggcagccccg cagctgcagc tgcagcgcgt gcaggcgcga ctgcgctggc agcgccaggc
     2941 cgagggctgg gcattgcagg tgccgcgcct gcgcctgacc acggacgagg gcgagcagcg
     3001 gctcgatggc ttgcaggtgc aggtgggcag gcagctgcgg gtgagcgccg cggcggcaca
     3061 ggcggggacc gcgttgcgtg gcctggccct gagcgatcgc ctgccggcgg acctgcgtcg
     3121 ctggctgttc ctgtcccggc cacagctgga ggtggctgag ctgcagctgg ccggcgaacg
     3181 cgacggcccg ttgtgggcgc agggcgaact gcagtcgctg ggctttgcca gcgtgggcgg
     3241 gtccccgggc gtgcgcggtt tgggcggccg tttcgagggc gatgccaacg gtttcagcct
     3301 gcagctgcaa ccgcagcgcc agctgcagtt cgattggcca acgggctttg gcgtacgcca
     3361 cgacctgcac ctggcagggc aggtggtggg ctggcgcgac gaaggcggtg gctggcgcat
     3421 cggaacgccg gcgatgcgcg tggaaggcac cgactacgcc gccgatgtgc gcggtggggt
     3481 ctggttccag ggcgatggca cgcggccgtg gctgcagctg gcggccaagc tggacgacgt
     3541 gccgatgacc gcggccaagc gcttctggat ccattccaag atgagcaagg gcgctaccga
     3601 ctggctggac atggcgctgg ccggcggcca ggtacgcggc ggtgtcggcc tggtcaccgg
     3661 tgacctggac gactggccgt tcgacaacca cgatggccgc ttcgaggcca ccggccacat
     3721 cacccagggt gagatccgct tccagcacga ctggccgttg atgagccagg tcgatgccga
     3781 catcgccttc atcggccccg gcttcgacat gcgcggacgc ggtgatctgg ccggggtggc
     3841 cgtgcagacc ttcgaagcgg gcattgccga cttcggccag cagcccctgt atgtgcgcgc
     3901 cgacgcgcag agcgaggccg gcaagctgct ggcgatgctg cggcaaagcc cgctgcacaa
     3961 ggactacggc gacaccctgg acaatctcac cgctgccggc cctgcgcacg tgacgttcga
     4021 tctgctgcag ccgctgcacc acgatgaagg gggcggccac ctgcagggca cggtcgatct
     4081 ggccggcgtg aagctggtcg acaagcgctt ccagctggcg ttcgacaaca tgcacgggca
     4141 ggcgcgctac agcaatggcg gtttcgatgc cgaggaactg tcggtgcggc atctcggcca
     4201 ggacggccgc ctgagcctgc gtgccggtgg ctacgtgcgt gacagcaggc tggccttcga
     4261 atcgcagctg tcggcccatc tcgatgccgg ggtgttgatc gaccgcgcgc cggaaatggc
     4321 ctggctcaag ccctatatca acggcacctc ggcctggacc atcgcggtga acctgcccaa
     4381 ggtggcgccg ggggcgccgg ccccgcccag cgagctgcgg ttgagttcgg atctggtcgg
     4441 gacccgcctg gacctgccgg caccgctgga caagccggcc accgagccgc tggcgacctc
     4501 ggtggccgcg cagctgccga tgggcgccgg ccgcatcgac gtggcgttcg gccagcgcct
     4561 ggccctggcc gcgcgcagcc acaacaacca gaccggcgta caggtcacgc tcggcagcga
     4621 ccgtgttgac cgcgagccgc cgccgaacgg gctgacggtc aatggccgca gcccgaccct
     4681 ggacgcactg gagtggatcg gcctggcacg cggcggcagt gacgatgatg cgatgccgct
     4741 gcgcgcagtg gacgtgcagg tcggccagct gaagctgatc ggcggcgtgt tcgagcagac
     4801 ccgcttgcag ctgcgcccgg gcgcgcaggc gctggacgtg cgcctggatg gcccttcgct
     4861 ggctggccgc ctgaccgtgc ccaacgccga aggcggcacc atcagtggcc agctcgaccg
     4921 cgtgcactgg caatcgctgc cggcggcgcc gggggcgacg ccggcaccgg cgcgggtgca
     4981 ggccggtgcc aatgacatgg acccggcaaa gctgccaccg ttcgcgctgg acattgccga
     5041 cctgaagttc ggcaaggtgg tgctgggcca ggcggtgctg cgcacgcgcc cgctggccaa
     5101 cggcctgaac gtggacgagc tgcgcttccg tgcaccggac caggaaatcg acatcagcgg
     5161 ccgctggctg ggccgcagcg gcggtgcccg caccgaactg accgcgcagg tgcgcagtga
     5221 agacctgggc gggctgatgc agaacctcga ctatggtggc cagttgcgcg ggggggccgg
     5281 ccaggcgcag ctgcaggcct cctggagtgg tggcccatcg gacttccagc tggccaatct
     5341 gcagggcagc ctggacctgc atgcgcgcaa cggccagctg ctggagctgg aaccgggcgc
     5401 cggccgcgtc ctgggcctgc tgagcgtcac ccagctgccg cgccgcctga tgttcgactt
     5461 ccgcgacttc ttctccaagg gcttcgcgtt caaccagatt gacggccgca tgcagttcgg
     5521 ccagggcatg gcgcgcaccg acaaggtgct gatcgaaggc ccggcggcga acatcaccat
     5581 ccgcggccag gccgacctgc gcaaccagca gttcgaccag accatcgacg tcaacccgcg
     5641 cgccggcaac ctgctgaccg tggtcggcgc ggtggccggt ggcccggtgg gggcggcgct
     5701 cggcgcggcc accaatgcgg tattgtccaa accgttgggc gagattggcg cccgaaccta
     5761 caaggtgacc ggtccatgga aggagccgaa ggtggaagtg atcgaacgca gccgagacaa
     5821 gaccccgcca gcgcccggac cggcgccggc accggccatt ccgcccaccg tcaccgacct
     5881 gccgcgctcg cgctgagccc ggccctccgt ccacggggtt gcctgagcgc ccccgcatcc
     5941 ccagatcgag accatgactg atatcgccct gacgcttgcc caagaccgcc tgctgcgccc
     6001 cggtggcctg gataccgccg gcctggagcg cgccttcggc cagttgctcg gcccgggtgt
     6061 cgacttcggc gacctctatt tccagcacgc ccggcgcgag agctggagcg tggaagacgg
     6121 catcgtcaag gacggcgccc attccatcga gcagggcgtg ggcgtacgcg ccatcgccgg
     6181 tgaaaagacc ggtttcgcct attccgatga catccacgcc gacgcactgc tgacggcggc
     6241 gcagtcggca cgtgcgatct cgcgcgaagg cggggcccag tcgggtcgct cgctgctgcg
     6301 gggcaccgcg cgcgcgctgt acccggcgct ggacccgatc gacggcatcg gcaacgaggc
     6361 caaggtcgag gtgctcaagc gcctggacgg ttacctgcgt gccgccgacc cgcgggtgaa
     6421 gcaggtgatg gtcagcctgt ccggcggcgt cgacaccgtg ctgatcgccc gcagcgatgg
     6481 cgtgctgggt gccgatgtgc gcccgctggt gcgcctgaac gtgcaggtga tcgtcgaaca
     6541 caacgggcgc cgcgagtccg gctactccgg tggcggtggc cgcttcggct acgacgaact
     6601 gttcgccggc ggccgccccg aagcgctggc ccgcgaggcg ctgcgccagg cgctggtgaa
     6661 tctggaggcc gtgccggccc cggccggagt gatgccggtg gtgctgggcc cgggctggcc
     6721 tggcgtgctg ctgcacgaag ctgtcggcca tggcctggaa ggtgacttca accgcaaggg
     6781 caccagcgtc tatgccgggc gcatcggcga acgcgtggcg gcgccggggg tgaccatcgt
     6841 cgacgacggc accctcgacg ggcgccgcgg ctcgttgaac atcgacgatg aaggccatcc
     6901 gacccagtgc accacgttga tcgaggacgg catcctggtc ggctacatgc aggacagcct
     6961 caatgcgcgg ttgatgggca tggcgcccac cggcaacgca cgtcgtgaat ccttcgcgca
     7021 cctgaccatg ccacgcatga ccaacaccta catgcgcgcc ggacagcacg acccgcagga
     7081 gatgatccgt tcggtgaaga agggcctgta cgcggtgaac ttcggtggcg gccaggtcga
     7141 catcaccagc ggcaagtacg tcttctcggc caccgaggcc tacctgatcg aggatggccg
     7201 catcaccgcg ccggtgaagg gcgcaacgct gatcggcaac ggcccggaaa ccatgcagaa
     7261 ggtgcgcatg atcggcaacg acctcgccct cgatgagggc gtgggcgtct gtggcaagga
     7321 cgggcagagc gtgccggtgg gtgtcggcca gccctcgctg ttgatcgagg gcatcaccgt
     7381 cggcggtacc caggcctgag cagggccatg gccgcggcca gcgccctggc cgacacggac
     7441 tcagtccgtg tcggcgtcgt cgaccgtgtc gtcggcgtcg tcgccgctgg ccgtcttcag
     7501 gcccagcgcg gccggcagca tcagcccgcg cagcacctgg tagatctcgc ggtaggcgcg
     7561 cggcggcttg ttcctggcct tttcggcctg ggcattgcgt accagcgtgc gcagctgctg
     7621 gcggtcggcc tgcgggtagt cgtccagcag cgcggccagc gccgtgtcac cgtcggccag
     7681 caggcgctcg cgccagtctt ccacgcggtg catcatcgcc acctcgcggc ggccggtttc
     7741 gctgttggcg tccagcgcat cgcggatcgc ctccagcgtg gcctcgtcct cgcggcgcat
     7801 gtgcttggcc aggaacgcca gctgccgctt gtgggcgatg tgcgcggtga tccgcttgca
     7861 ctcggcgatg tgcggcagca ggtcctccgg aatcggcagg cgcgccagct gggccggggt
     7921 cagcgacacc agcttctcac ccagggccag tacttccagg gcttcgccgc gcttctgctt
     7981 gcggctcttg tcaaggaatt caccggtttc ttcgtcgcgt ccgcgcatcg tccacacctg
     8041 ctttcaaaaa aagtcgcccg gcgtgatgcc gggcccaacc tgcacaggat aaagcattga
     8101 acgtgatcgc ccctgaagtc gccgtcggtg acgacagccc ggcccgcctg gaacggctgg
     8161 ccgacctttc ccagcagctg ctcgaccgcg cccgcgcgct gggcgccagc caggccgaag
     8221 tcagctgcag cgaggaccgc ggcctggatg tcaacgtccg cctgggtgag gtggagaccg
     8281 tgcagtccac ccgcgaccgc ggtatcgccg tgaccgtcta tttcggccag cgcaagggca
     8341 gtgccagcac cggagacctg aacgagagca gcctggcggc caccgtcgag caggcctgcg
     8401 cgatcgcccg gcataccgag gacgaccctg ccgccggcct ggccgaggcc gcattgatgg
     8461 ccacccactt cccggaactg gacagttggc acccgtgggc gctgcaggcc gatgaggcgg
     8521 tggacctggc gctggcgtgc gagaacgccg ggcgcgaggc cgacgcgcag atccgcaact
     8581 ccgacggcgc ctcggtgtcg agcatgcaga gcctgtcggt gtacgccaat tcgcatgggt
     8641 tcatcggccg cgagcgcggc acccatcatt cgatcggctg tgcgctgatc gccggccagg
     8701 gggatggcat gcagcgcgac ggctggtaca ccagcgcgct ggcccgcgag gacctggagg
     8761 acgtgggccg ggtcgggcgc caggccgccg agcgcaccgt ggcccgcctg cagccgcggt
     8821 cgctggcgac cggcagcatg ccggtgctgt ttgccccgga agtggcgcgc agcctggtgg
     8881 gacacctgct gacggccgtg tccggcggcg cgctgtaccg ccaggccagc ttcctgctgg
     8941 acagcgtcgg ccagcgcctg ttccccgagt ggatgcagat cgacgaactg ccgcacctgc
     9001 gccgcggcct gcgttcggcg gccttcgatg gtgatggcgt ggccacccgc gcctcggcgc
     9061 tggtgcgtga cggcgtgctg cagcgctacg tgctgggcag ctactcggcg cgcaagctgg
     9121 gcctgcagac caccgccaat gccggcggcg tgcacaacct gcagctggcg gccaatgccg
     9181 gctcgctgca cgagatcgcc gcccggatgg gcagcggcct gctggtgacc gagctgatgg
     9241 ggcagggcgt gaacggggtg accggcgact attcgcgcgg tgccggcggc ttccgtgtcg
     9301 agaacggcga gatccagtac ccggtggacg gcatcaccat cgccggcaat ctgcgcgaga
     9361 tgttcagcag catcgaggcg gttggcagcg acgtcgaccc ccgctcgcac atccggaccg
     9421 gctcgatcct gcttggacga atgaccatcg ccggtaatga ttgatggcgt tgatggcgta
     9481 agctatcccc gcctgacgca atcagcctgg tgctggtggg tcaagaccac ccaatgaaaa
     9541 ggagttttgt cgtgagtgaa ttcgataacg tcccgccgcc gccggccacc accaatgcgc
     9601 cggccgacca gcgcaccatg gccctggctg cccacctgct gggcatcttc acctggttca
     9661 tcggcccgct gatcatctgg ctgatcaaca aggatgatgc cagcaaggcc ttcgtcaccg
     9721 accaggccaa ggaagcgctg aacttccaga tcaccatcac catcgcgatg ctgatctgca
     9781 tcgtgctgac catcgtgatc atcggcggca tcctggcgcc gatcgtcggc atcctgaacc
     9841 tggtgttctg catcatcgcg gcggtgaagg ccaacaacgg cgaagcctat cgctatccgt
     9901 tcgcgctgcg cctggtcaag taagaccgtc cgcatgtgga acggaaaacg cccggcactg
     9961 ccgggcgttt tttgttggtg agcgcgcagc gtggctgcga tcagtgatcg cgttccaccg
    10021 ccagcgttgc cagcgcgcgc agcgcatcgc cctcttcgcc gtagccggcc aggctggact
    10081 gcatgcgcgc agccagttca cgcagctgcg ccttggcgcc gtccatgccg agcagcgcgg
    10141 ggaaggtgct cttgtcctgt gcctggtcct tgccggcggt cttgcccagc tgttcggaac
    10201 tggcttcgac atcgaggatg tcgtcgcgca cctggaacgc caggccgagc gcgtcggcga
    10261 aatgatccag ctgggccagc tgcggctcgt gggcctggcc gcacagcgcg cccatgcgca
    10321 ccgccgcgcg gatcagcgca ccggtcttga gcgcgtgcat gcgggtcagt gccgccagcg
    10381 actgctgctg gccggtggca tcgatatcca gggcctgccc gccgcacatg ccggacgcac
    10441 cggacgcatg cgccagggtc tgcaggcagg ccacgcgcag ggtggccggc agcggtgcgt
    10501 cggccagcag gccgaaggcg cgggtctgca gcgcgtcgcc ggcgaggatc gccgtggctt
    10561 cgtcaaaggc gatgtgcgtg gtcggcttgc cacggcgcag tgcatcgtcg tccatcgccg
    10621 gcagatcgtc atgcaccagc gaataggcgt ggatcagttc gacagccatc gccgccgcat
    10681 ccagggtttc ggcctgcgcg ccgaacagct ggccgctggc gtacaccagc agcgggcgca
    10741 tgcgcttgcc gccgccgagc accgaatagc gcatggcctg gtgcaggcgc tgcggcgctt
    10801 cggcgggtga gggcagggcg gcatcgagct ggctttcgat gcggtcgcgc cagcgcgcga
    10861 acagcagctc agccgtcatg gctgggcgga tcgaagggct cggacgtttc cggctgggcc
    10921 ggatcgctga gcaggcgcac gcgcagttcc gcctgctcca gcgcctgctg gcactgccgg
    10981 tacaggccga cgccacgttc gtaagcactg agcgaagctt ccaggctcag ctcgccggtt
    11041 tccatctgct ccaccagctg ctccagcgat tcaagcgact gctcgaactg ggcgaccggg
    11101 gaggcgtttt cgggggactt cttggccatg cggcaagtgt ggacgggctg cgcgcggggg
    11161 tcaattcacc aaccgccggg acgccactgc agctgcgcgt cccgggccag cagccatgcc
    11221 tgcaagggcg cgctgatgac cacgtcggcg gcggccagca gttgtccgtc cgcaaacagc
    11281 agcggcagct gcgcgcgtcg ccacggcgcg aggtgctcgc gttgcaggca gtccttcagc
    11341 gcatgggcat gctggcggcc gggcatcagg atgcgctcgc cacccacccg cgcacggatc
    11401 tgcaacggct gctcgaaagc actggcaccc cgcaggcgca gctggccgcc gtcgggcagc
    11461 ggcaatggcg cgcggccatc ccatgtggcc tgccagtcgg cgggcagagc cggcagccgc
    11521 gcaggcagca gataggcatg gtcgcgccat tgccggatgg catggtcgtg ccagcgtacc
    11581 tgtgcctgac ggtcattggc tgccggcagc agctgctcca gtgcctgctg cagcaccgtg
    11641 gccggcagcg gcggggcgcc gtggccgagc acccaggcgc gcagcacgcg cgcggcacgg
    11701 cccggcgaaa cctggcgcag cagttgcagc gacagcacgc gtggtgcgac ttccaggtgt
    11761 gcgatcagtt cggcgtcttc ttcgtccagc agttcgcggg tctgccggca gtgcgtcgcg
    11821 ctgccggcca atgccgcagc ggcatgcgcc catcgctggc gcagcagcgg cagtacgtgc
    11881 agacgcagga agttgcgatc ggcgtggtct tcgctgttgc tggggtcttc gatccagcac
    11941 agcgcgtgct gcctggcgta gtcgagcagc gcgccgcgtg gtgcatgcag caacgggcgc
    12001 cacaggcggt gtgcgccgag ctgattgtgc tcggccatcg cggcaagtcc atcgacgccg
    12061 gaaccacgca gtgcacgcag caggaaggtc tcggcctggt cgtcctggtg ctgtgccagc
    12121 gccagtgttt cgccgtcgcg cagttcggcg gcgaacgcgg cgcgccgtgc ctggcgcgcc
    12181 gcgccttcca ggccgaggcc agggtgcaga tcaacctgca cgcggtgcac ggccagttcc
    12241 atgcccagcg ctgcgcactg ctgctggcaa tgccgcaccc agtcatcggc ggccggttgc
    12301 aggccgtggt gcacgtgcac tgcgcgcagc ggcgtggcag aggcctgggc gcagcgccac
    12361 agccagtgca gcagcacggt cgagtcgaca ccgccgctgt agcccaccag cagcggtgca
    12421 tccagcggaa cgagggcagg gaaggcggtc acggcggcaa gtatagggtt gctcggcagg
    12481 gctgcgccct gcacccgcta cgatccagag caacagcaac agcaacagca acagcagaag
    12541 ctggtttcct gagggtaggc ggtgtgggtc cggttgcggg ggacgccgta aatacgtcca
    12601 tgtaggctcg gtcgcgccat ccatggcgct cacgcccccg caaccggacc cacaccgcct
    12661 tcgacagacc ccgcgatctg ttggaatggc atggggtaac ggcatggggt cagatccgtt
    12721 ttccgcagga aaacggatct gaccccgggt tcaattcgat atctgacaga tacgatccac
    12781 gcaaagcgtg gatggtccag ccgtcaccgg aaaactgtcg aaggtggggc ggtgtcggat
    12841 tgcggggtgt cagccgcatg gatgcggctg ccaaacctac aaggacgtac ttgcggcgtc
    12901 cccgcaatcc gacaccgccc cgccaaaccc gcagataatc cggagccggc tgttgctttt
    12961 gaggttgacg ttgattcggc aggagcaggg cgcagccccg ccgaaaacct tacttcagcc
    13021 tacgacccgt gcggtcgatg cggaaccact cgccgccttc catcggtgta tggccatcgc
    13081 catccggcgt gccgcgacgg cagccgttgc agacctcggc cacgccgtcg cggaacggcc
    13141 aggcgaaatc gaaggtgccc ggtaccacct gacggaatgt cagatcgaag tagcccacgc
    13201 gattgcccac gcgcccgcgc agcaggcctt cctccggcgt ttccgggccg ttgtcccagg
    13261 tcagcaccgg caggctgcgg ccggtgcggt cgacgtaatg gaagccctgg tcggcataca
    13321 ccacggccag gccgtggtca tcaaagttca ggtcctgcag tgtgcccggc tggatcttcg
    13381 gccggtgatc gaccacctcg cagttgggca gcggccacaa gccgtgttcg tcggtgagca
    13441 gcttgcatgc cggcgcctgt gccagcgcgt tggcactggc cagcatcccg aacagggcca
    13501 gcgaccgcgc gaagcggccg ccggcgcggg cagggcgggc ctgccgcagg gtcacttgtc
    13561 ctcggccttg cgctcgaacg cggttggtgc cggcagctgc accggcacgc ccttgtcgtc
    13621 gcaggtgccg gcctggcaca ggcgctcgcg cagtgccggg gtggcctgca cgatcatgtg
    13681 gtagatcgcg ttctgttcca gcgtgccgcg gatcgccttg ctgcccgggc cacgcgccca
    13741 gatgccgacg tcctcgccac cgtgcgactc ggacttcatc ggcaccagtg cttcctgcat
    13801 gtagtcggga tgctcggtgt cgacctcgcg caggttcggg cggccgttgg ccggttcgaa
    13861 gctgctcggg ttgtgcgggt aacgcttcgg gccggccggc tgctggttgc tgctaccggt
    13921 atggcccggg ccgttggcat agctcagcgt ggtgtacggc tggccggtgc cgtccagcgc
    13981 gtaatccagc ttgccggcgc catcttcgcc acccttgtcc ttcaccttgc ccaggatcgg
    14041 gttgccgcgc gccgggtagc cgacgaagtt caacgtgtgc gaatggtcgg cggtgacgat
    14101 gatcagggtg tcatcggccg aagtcagctc gttggccacg cgtaccgcgt cggacagcgc
    14161 cacggtttcg gtcagcgcac ggtaggcgtt gccgctgtgg ttggcgtggt cgatgcgcgc
    14221 gccttcgatc atcagcacgt agccttccgg gtgctgggac aggttcttga tcgccgcagc
    14281 ggtcagctcg gccaggctcg gctcgccgcc cggatcctgc ggacgctcgt gctcgtagcg
    14341 catgtggtcc ggctcgaaca ggcccaggat ggccggcgcg ttggccgcag ccgccagttg
    14401 cttgctgttc cacacgtagg cgccctgcgg atgggcctgc tgccattcct gcaccaggct
    14461 gcggccgtcc agacgctggc cgaccttgtc gtcgtactcc ggatcgcgct cttccacagt
    14521 ggtgaactca ccgcggccgc caccgagggc caccagcggg ccgcggccgt aacgcgaggt
    14581 cgacagcagc tgctgggcga tgtccttgca gccggcggcc ttggccgcgt cggtcaggtc
    14641 ggtgtcgttt tcccagttgc gctcgggcga gtgcgcatac gtcgccgccg gagtggcgtg
    14701 ggtcaggcgt gcggtggaca ccacgccggt ggccaggccg gcgctgtcgg ccagctgcag
    14761 ccaggtcagc aggcccttgg acaggctgtc ggcacagtcg gtgcggctgc cggcgctgac
    14821 gccgatcgcg cccatgtggg tcttcacgcc ggtggtgatg gcggtcatgg tgccggccga
    14881 gtccggcgtc tgcgaatcgg tgttgtaggt cttgctgaac gccgtggccg ggaagcgctc
    14941 ccaggacagc aggttctctt cgcccgagcc gcccttgcgc tggccttcgt agatgcgcga
    15001 ggcggccacg gtggtcagac tcatgccgtc accgaggaac aggatgacgt ttttggcctt
    15061 tccggccatc gcaccattgg ccgccgcctg ggcggcgccg ctgcggtacc accactgcgg
    15121 tgtctcgccg gccgggtgcg cgaccgggtc gacggcgacc ttcaggccgg ccggggcaga
    15181 ggcgggggta gtgctggcgc aggcgccgag cagcagggtg gtggcacagg cggccaacag
    15241 ggagacggaa cggcgcatgg acgctgggat ctcacaaact gtaacgggac gttcattatg
    15301 cccggccctg caaggcacgc cgatgacaca ctgatttgcc ggccgggcgg tcgttccgcg
    15361 ggccaggttg ggctatcgtg ccagcatccc ttccttcccc tctggattgc ctatgaagct
    15421 ggtctctgcc tggctgcgga ttccattctg gcagcgcgtg gtcggtggct tcgtgctcgg
    15481 cgcgctggcc ggctgggcgc tcggcccggc cgcggaaacg tggtttggcc cgctcggtga
    15541 gctgtacgtc accctgatca agatgatcgc cgtaccgttg gtgttcttcg cggtcatcaa
    15601 tgcgatttct tctctgcatg gccagaagtc ggtcgccgcg ctcagtggcc gcaccttcct
    15661 gtggttcgtg atcaccgcag cgctggcggt atgcgtcggc ctggccgtgg gcaccgtgct
    15721 gcagccgggt gccggtggac tgcagttgtc gatggccagc aactacgtac cgcgcgaagt
    15781 gcccagcgtg gtgcaggtgc tgctggatgt ggtgcccgcc aatgtcttct acgcgctgtc
    15841 cggcatcggc accaaggtca atgccgctgg tgagaccgtg ctggcggccg gccgcggctc
    15901 gatcctgccg gtgatcttct tcgccggcct ggtcggcttt gccatcgtca agctgggcga
    15961 gaaggtgacc gaggcgcgca agctggtcgg ccagatgagc gacatcatga tccaggtgac
    16021 ccgcttcgta ctggaagtca ccccgatcgg caccttcggc ctgatcgccg gcctggtcgg
    16081 cagctacggt ttcgagaagc tgctgccgct ggggcatttc gtgctggcgc tgtacgtggc
    16141 ctgcgcgctg cacatcgtgg tggtctacag cgcactgttg atggcgcatg gcctgaaccc
    16201 actgaagttc ttccgtggcg ccgcgccggg catgcaggtg gcgttcgtca gctcgtccag
    16261 cttcgcggcg atgccggtgg cgctgcgttc gatcacccac aacctggggg tgaacaagga
    16321 ctacggctcg ttcgcggtgc cgctgggtgc cagcatcaag atggacggct gcggtgcgat
    16381 ctacccggcg ctgtgcgcgg tgttcatcgc gcagtacagc ggcgtgccgc tgaccccgga
    16441 acagtacgtg gtggtgctga ttgcttcggt gctgggcagc ttcggtaccg ccggtgtgcc
    16501 gggcacggcg gtgatcatgg ccacggtggt gctgagcgcg gccaacctgc cgctggaaac
    16561 catcggttac ctgtatgcca tcgaccgcat cctggacatg atgcgcacga tgaccaacgt
    16621 gaccggccag atgctggtgc cggtgatcgt ggccaaggag accgggctgc tcgaccaggc
    16681 ggtgtatgac aacccgtcca gcaatgtcgg tgtggatgac cccgacccga cgccgccgcg
    16741 cggctgaggt tgcgtggtgg tgatggaagg cccgccctga ccggcgggcc ttttgttttg
    16801 ttccggtaga tccacgccat gcgtggatgg cggccgtgcc gaccaacggt cggcacccac
    16861 ccgggcagct ggcgctgtgc cgaccgaagg tcggcaccca ccggggcatg tggcgctgtt
    16921 ccgaccgaag gtcggcaccc accggggcat gtggcgctgt tccgaccgaa ggtcggcatc
    16981 caccggggcg caaacaaaaa agccgctgca gggcagcggc ttttcgtctc tcaggcggcg
    17041 cggtggcgcc agcgggtcag aggtcgaccc ggcgggcctg catgaacttg ttgccccagt
    17101 agccactgag cagggtgtcc acgcggacgt ccttgcccga gctcggtgcg tgcaggaaac
    17161 ggccatcacc gacatagatg ccgacgtggt cgacgcggcc cttgcggccg aagaacacca
    17221 ggtcgcccgc ggccagcgcg gtgcggtcgt tgatcagttc ggcgttgtcg tcgtgggcca
    17281 tctcgcgcga cacgcgcggc agttcgatac ccagcgcaga acggaacacg tagccaacca
    17341 ggccgctgca gtcgaagccg ctgtccgggt tgctgccgcc ccaacggtac ggggtgccca
    17401 gcagggtcat cgcgcggcgc agcagcgact gcaccttgcc attgtcggcg gcggtgccga
    17461 caacgctgcc attggcggcg ctgctggtgt cgtagttggc gagcaggcgg ctgagatcgc
    17521 cggccaccac ggccgagcgg tccatcagcg gaatggtgtc gttggcggcc aggtgcggca
    17581 gcagggcggc cagcgtggcg ctggcggcgg catcgacgcg gctgcgctgc ggagcggcag
    17641 cctcggcctt ggcggccggt cgggcggtgc tctcggccac cggggccggg gtcacatcgg
    17701 aggaacggtt cggagcggtc tgcgaccagg ccggaaggct ggtcaggcac agtgccaggc
    17761 caagcaacag cgggcgggca ccacgtgaag atacggaagt ctggccttcg cttttcaggt
    17821 cgtcagtcgt cacgcgtcgg tcacaggaaa aaaacgatgg ggcatcatgc cctgtaaaag
    17881 cgcggataag ttaaaaattc cgttagtaat ccgttagttt catagtgatg tgcgtcacat
    17941 ttttgaacat atcgcctgtt cattttagcg aagaacgcgt ttcgcccccg tgtagtggtc
    18001 cttccagtaa ggcccactga gcgagtcgag ccggaccgtg ccgccggtgc tgggggcgtg
    18061 cacgaaacgc ccttcaccca cgtagatgcc gacatgggtg acgttgccgc ggctgccgaa
    18121 gaacaccaga tcgccggtgg ccaggcgctg cgggtcgatc ttcgggccct gtaccgcagc
    18181 caggtcacgc gaggtacgtg gcagcttcag gtccagcatc tcgcggtaga cgtaggccac
    18241 caggccgctg cagtcgaagc ccgaatcggg ggtattgccg ccgtagcggt agggcgtgcc
    18301 gaccaggctg atggcgcgca tcagcaccga attggccgcc tcggggttgt ccggcacggt
    18361 cttcggccag tgcgcggttg gcggtggcgg agcagggcgg gtggccttgc cgccgccgca
    18421 ggcggtcagc aacaggggca gggccagcag cagggccggg gtgagcaacc ggcgcgggcc
    18481 ggacgaaact ggcgtgatgt gcatgatctc cggataatgc gccaccttgg attggccgtc
    18541 atgatggcgg cgtccccgcc gggccacaac ccgccccaac ccgcctgcct ccggcagatc
    18601 cagacagagt tgcgcatgaa gatcgaaaaa gaccgcgttg tccgcttcca ctacaccgtt
    18661 tccgaagccg gccaggagcc gatcgagtcg tccaaggacc gcggcgagcc gctggcgatc
    18721 ctgatcggcc acggcaacat cattccgggc ctggaaaacg ccatgatgga caaggaagcc
    18781 ggcgcgacct tcagcgtcga cgtcaaggcc gccgatgcct acggtgagcg tcgcgagggc
    18841 ctgtcccagc gcgtgccgaa gaagcacttc ggcaacacca agctggcccc gggccagcag
    18901 gtcgtgctgc agaccaactt cggcccgcgt gcggtgaccg tgcagaaggt cggcatgagc
    18961 gtggtcgacg tggacctgaa ccatccgatg gccggcaagg acctgcactt cgacgttgaa
    19021 atcgtcgacg tgcgcgaagc cggcaaggaa gagatcgatc acggccacgt ccacggcgac
    19081 ggcggtcacc agcactgatc gtcgcgcgat agtgatggca gcaacggccc gcttcggcgg
    19141 gccgttgcgt ttctggaaca cggcgcggcc atccatggcg cttgggccgg cggcataatg
    19201 gtggacctgc tcgacggacg ccccgtgaac gccgcttctc cttctctgca accgctggct
    19261 tccagcgaac gcatcgcggt gctggatgtg ctgcgcggtg ccgcgctgct gggcatcctg
    19321 ctgatgaaca tcgaggcctt cagcggtccg ctggacctgg ccttcaccgg tatcgacacg
    19381 cactggcagg gcctggacta ctgggccgat gcgttcgtct atgtgttcgt gcagggcaag
    19441 ttcttcaccc tgttctcgtt gctgttcggc gccggcttcg cggtgatggc gcagcgagcc
    19501 gaggtggccg ggcgtgcctt caccccgttc tacctgcgcc gcagtgccgg cctgctgctg
    19561 atcggcctgt gccatgcgct gctggtctgg tccggtgaca tcctggtgct gtacgcgctg
    19621 gtttcgctgc cgctgctggc atgccgcgag gcgccgcgca gctggctgcc gtggatgggc
    19681 gtgatcgtct atctgggcgg cgtggcgatg atgctgctgg tcggggcgat ggtgtcgatg
    19741 gcgccggtgg aggacctgca gaagatgctc gccgacgcac agcaggagat cgcccagcag
    19801 cgcctggtgt acgggcaggg cagctggatg caggccaacg cgcagcgcct gggcgagttc
    19861 ggatcgtcga tgggggcgct gctgattacg ggcccggaag tgctgggcat gttcctgatc
    19921 ggcagctggt ttgccggcag cggcgcactg gccaccccgg agcgcttcgt gcggctgtat
    19981 gcagtgttgc gctgggtggc gctcccgctc ggcctggtga tcacgctgct gggggttgtc
    20041 tggaagccgt atctggcacc gggtgcctat gatctgccgg tcaccgccgc gatggccctg
    20101 gtgacggtgg gcggtctgcc gatgtgcctg ggctacctgg cctggatcgt gcattggcgc
    20161 acgcggctgg cgtggttggc gccggtggga cgcatggcgt tgacccacta cctgggccag
    20221 tcgctgctgt gcacctggct gttctatcac tacggcctgg gcgcgttcgg gcagatgccg
    20281 cgcagcatgc agctgttgtt cgcgctggcg ctgtttgcgg tgcaggtggg catttcgcac
    20341 gcctggctgc ggcgcttccg tttcggcccg atggaatggc tgtggcgcgc gatgacgtac
    20401 cggcagtggc cgccgatgcg gcgcggagcc gggcagggct gatcgatgca gggcgcgcgc
    20461 gaggatgtga tcgtggtggg cgccggtgcc atcggtctgg ccactgcgct cgcgctgcgc
    20521 gcgcagggcc ggcaggtgcg ggtgatcgaa cgggggcgca tcggcggcgc gacctcgcat
    20581 ggcaactgcg gcaccatcac gcccagtcat gcgccaccgc tggcggcccc cggtgtaccg
    20641 ctgcgtgcgc tgcgctggat gctcgacccg cgcgcaccgc tgtatgtgcg cacgcggctg
    20701 gacccaacgc tgtggcgctg gttgctgcag ttcggcgcgc gctgcaacgc gcgggactgg
    20761 ctgcagtcca cgcgggcacg cggcgcactg ttgaatgatt cgcggctgcg cctggcgcag
    20821 tgggtgaaga cacacgcgct ggactgcgaa ttcaaggcgc gcggtctgga ttacgtgtt
//
