LOCUS       NZ_CP090423            22694 bp    DNA     circular CON 08-MAY-2024
DEFINITION  Stenotrophomonas maltophilia strain GYH chromosome, complete genome.
ACCESSION   NZ_CP090423
VERSION     NZ_CP090423.1
KEYWORDS    RefSeq.
SOURCE      Stenotrophomonas maltophilia
  ORGANISM  Stenotrophomonas maltophilia
            Bacteria; Pseudomonadota; Gammaproteobacteria; Lysobacterales;
            Lysobacteraceae; Stenotrophomonas; Stenotrophomonas maltophilia
            group.
REFERENCE   1  (bases 1 to 4791742)
  AUTHORS   Cheng,Z., Zhao,P., Chen,J., Zhao,J., Yu,J., Zhang,S. and Guan,Y.
  TITLE     Aerobic biodegradation of trichloromethane by Stenotrophomonas
            maltophilia GYH: Biodegradation characterization, genome functional
            analysis and metabolic pathway determination
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 4791742)
  AUTHORS   Cheng,Z., Zhao,P., Chen,J., Zhao,J., Yu,J., Zhang,S. and Guan,Y.
  TITLE     Direct Submission
  JOURNAL   Submitted (28-DEC-2021) college of environment, Zhejiang university
            of technology, 18 Chaowang RD, Xiacheng District, HangZhou, Zhejiang
            313200, China
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: Canu v. v1.5
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 27.0x
            Sequencing Technology             :: Oxford Nanopore
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_023518235.1-RS_2024_05_06
            Annotation Date                   :: 05/06/2024 14:53:59
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 4,547
            CDSs (total)                      :: 4,455
            Genes (coding)                    :: 4,428
            CDSs (with protein)               :: 4,428
            Genes (RNA)                       :: 92
            rRNAs                             :: 5, 4, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 5, 4, 4 (5S, 16S, 23S)
            tRNAs                             :: 75
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 27
            CDSs (without protein)            :: 27
            Pseudo Genes (ambiguous residues) :: 0 of 27
            Pseudo Genes (frameshifted)       :: 8 of 27
            Pseudo Genes (incomplete)         :: 22 of 27
            Pseudo Genes (internal stop)      :: 0 of 27
            Pseudo Genes (multiple problems)  :: 3 of 27
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 12:15:52
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 829900
            Orig. end                         :: 852594
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP090423.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            Bacteria and source DNA available from Zhejiang university of
            technology.
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..22694
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="lanthipeptide-class-iv"
                     /region_number="2"
                     /rules="(cds(LANC_like and Pkinase) and not micKC)"
                     /tool="antismash"
     cand_cluster    1..22694
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(cds(LANC_like and Pkinase) and not
                     micKC)"
                     /kind="single"
                     /product="lanthipeptide-class-iv"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..22694
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:12694](+)"
                     /cutoff="20000"
                     /detection_rule="(cds(LANC_like and Pkinase) and not
                     micKC)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-iv"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..12694
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(cds(LANC_like and Pkinase) and not
                     micKC)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-iv"
                     /protocluster_number="1"
     gene            complement(917..1216)
                     /locus_tag="LZ605_RS04060"
                     /old_locus_tag="LZ605_04060"
     CDS             complement(917..1216)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005413574.1"
                     /locus_tag="LZ605_RS04060"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LZ605_04060"
                     /product="hypothetical protein"
                     /protein_id="WP_107230649.1"
                     /transl_table=11
                     /translation="MSYKILYITLRRLIGERDVAALRSQLLQHGPVMFARALSLGSPRV
                     VADALSLLPISERINVLRHLPYPLRDAMKPLCIGGSQRLHMQPWSPAVLAMRHA"
     misc_feature    complement(1409..1425)
                     /note="TFBS match to NtrC, Nitrogen regulatory protein C,
                     confidence: medium, score: 23.74"
                     /tool="antismash"
     gene            complement(1498..1794)
                     /locus_tag="LZ605_RS04065"
                     /old_locus_tag="LZ605_04065"
     CDS             complement(1498..1794)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006369762.1"
                     /locus_tag="LZ605_RS04065"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LZ605_04065"
                     /product="hypothetical protein"
                     /protein_id="WP_249843913.1"
                     /transl_table=11
                     /translation="MTGFRFVPAALVVAAGLLLGACSKPQEPSKTAAEEVTQVKLIPPY
                     ESLDKDKDGIVTLAEVDAVAPDWAQRLHACDTDRDKTLTRGEYDVCRNTSGSH"
     gene            2053..3225
                     /locus_tag="LZ605_RS04070"
                     /old_locus_tag="LZ605_04070"
     CDS             2053..3225
                     /GO_function="GO:0005215 - transporter activity [Evidence
                     IEA]"
                     /GO_process="GO:0006810 - transport [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1029: RND family
                     efflux transporter MFP subunit"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005413572.1"
                     /locus_tag="LZ605_RS04070"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LZ605_04070"
                     /product="efflux RND transporter periplasmic adaptor
                     subunit"
                     /protein_id="WP_249843914.1"
                     /transl_table=11
                     /translation="MRIPLLSARLRRRHLALGALLLVVLSLLMLFHGVSRGDAQPASAP
                     PPVPVVTGRVEQQDIAHWRNGLGTVQSLQSTVLRPQVDGVLTEVLFEEGQKVRKGQLLA
                     RIDDRAIRADLGGAQAAVARDRATLDAARSDLARLQHLSSDQLVSRQMLEQQAATVQQL
                     QATGRGNQAAVDAAQVQLSYTRILAPMDGRIGLRQVDPGNLVRASDTQGLVTVQQTDPI
                     SVVFALPQDTLPQLRQALAAGVVPVQALDRDGGQLLAEGSLQVIDNQVEETSGTVRLRA
                     RFANADDRLWPGQLVSVRVRTGQSAATLVVDAAAIQRGIEGSFVYRVVADGSVEVLPVS
                     VGESENGKVAVQGELRVGDVIVRDGQSRLRPGVVVAEAASAPAAKRGAAP"
     gene            3222..6335
                     /locus_tag="LZ605_RS04075"
                     /old_locus_tag="LZ605_04075"
     CDS             3222..6335
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="resistance (resist) RND_efflux"
                     /gene_functions="transport (smcogs) SMCOG1049:
                     AcrB/AcrD/AcrF family protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014037327.1"
                     /locus_tag="LZ605_RS04075"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LZ605_04075"
                     /product="multidrug efflux RND transporter permease
                     subunit"
                     /protein_id="WP_249843915.1"
                     /transl_table=11
                     /translation="MSARVSLSSWFVRHPVATTLLTLAVILLGVAALPQLPVAPLPEAE
                     FPTIRVNANLPGASAETMASAVATPLETQLTGVPGIIEMTSTSALGSTSITLQFDLEKD
                     IDTAAQEVQAAINAAAGRLPSDLPNLPTWRKVNPADSPILVLSVVSAQMSMTELSDLAE
                     SRLARSISQISGVSEVNIVGQQRPAIRIQAQPERLAAMGMTLSDLRGVAQNASLNQAKG
                     ALMGGQRTSTFEANDQLFDAQDYRQLVVAYRDGSPVTLGDVAQVVDGAENAYVQAWPNG
                     QPGVGLIISRQPGANIVRTTDAVLAALPALRANLPASVDVEVLNDRTRTIRASLHEVEV
                     TLVLTIVLVVLVMGLFLRQLSATLIVGAVLVVALVATFAAMYVAGFSLNNLTLVALVVA
                     VGFVVDDAIVVVENIHRHREAGLGPMEAALKGAGEIGFTVVSISLSLIAAFIPLLFMGG
                     VVGRLFAEFALTITVAILISIVASLTLAPMMAAHLMKRMPAHRDGQDTLAGRLLAGYDR
                     SLQWALGHQRTVLLGFGATVAVAVASYVMIPKGFFPLQDTAFVIATTEAAQDIGYEQMA
                     AKHRQLAAIAAEDPALQAYNHAVGATGGSQTLSNGRFWFVLKDRGDRDVDVHAFIDRLR
                     AKMASVPGITVYMRAAQDINLGAGPARTQYQYALRGQDSRELSRWAEQLTERLRGLPQL
                     RDVSNDQQVGASVTRLQIDRTAAARFGLTANDIDQVLYDAFGQRQINEFQTETNQYRVI
                     LEIAPGMLGEVDALSYFHLRSPLTGQMVPLSAVAQVQPPGNGPLSISHNGMLPAVNLSF
                     NLAPGVSLGEAVQLVEQAQVQLGMPASISGRFQGTAQAFQESLASQPLLILAALLAVYI
                     ILGVLYESFVHPLTILSTLPSAGIGAVLMLWLWGLEFSIMALIGIVLLIGIVKKNGILM
                     VDFALDAQRNRGLSPLQAIHEACLTRFRPIMMTTLAALLGAIPLMIGFGTGSELRQPLG
                     VAVVGGLLISQLLTLYSTPVIYLALDRLFLQRRRERRAEEGAALTEPG"
     gene            6332..7021
                     /locus_tag="LZ605_RS04080"
                     /old_locus_tag="LZ605_04080"
     CDS             6332..7021
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1008: response
                     regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008267773.1"
                     /locus_tag="LZ605_RS04080"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LZ605_04080"
                     /product="heavy metal response regulator transcription
                     factor"
                     /protein_id="WP_107230645.1"
                     /transl_table=11
                     /translation="MKLLIVEDESKTAHYLRTGLGEQGWAVDLAADGVTGLHLAREFDY
                     DVIVLDVMLPGMDGFNVLRELRRSKQTPVIMLTARDRVDDRVHGLGQGADDYLVKPFSF
                     IELLARLQALVRRGRQQEPTELQVGDLQVNLLARRAYRDGARLDLTGKEFALLALLAQR
                     RGQILSKTVIAAQVWDINFDSNTNVVEVAIKRLRGKLDGPYPSKLLHTVRGMGYVLEVR
                     EDEDGPR"
     gene            7018..8376
                     /locus_tag="LZ605_RS04085"
                     /old_locus_tag="LZ605_04085"
     CDS             7018..8376
                     /EC_number="2.7.13.3"
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0000155 - phosphorelay sensor kinase
                     activity [Evidence IEA]"
                     /GO_function="GO:0004673 - protein histidine kinase
                     activity [Evidence IEA]"
                     /GO_function="GO:0016772 - transferase activity,
                     transferring phosphorus-containing groups [Evidence IEA]"
                     /GO_process="GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /GO_process="GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1003: sensor
                     histidine kinase"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014037325.1"
                     /locus_tag="LZ605_RS04085"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LZ605_04085"
                     /product="heavy metal sensor histidine kinase"
                     /protein_id="WP_249843916.1"
                     /transl_table=11
                     /translation="MRWSIAQRLSAMFAVAALLVFTLLGIGVYGVLERQVVRYQHAELQ
                     TKLHAVSGSVAMCDTRERWTKVREKVGNLISGDRDTLVWAWSDDPTFRIGSAQPQVQPP
                     GSHDDGMGTLQREGAHPLRTLYEHVPGKGVRPPVDLWIGIDSEPYTHALQRFAVALWVA
                     GVLGVLLVAGLGYWIARLGLAPLRALSDEARSLSPQRLSQRLDTAGLPAELGHLTGAFN
                     GALDRLEAAYTRLDAFNADVAHELRTPLANLMGQTQVALSRPRDNADLQEVMQSNLEEL
                     ERLRAIVNDMLFLSRAGQGDIAMDTRTVSLAEEVATAGEFLELLFEEAGLTLRIEGDAS
                     ARIDPSLLRRALTNLLHNAVQHARPGSVVRVQLQAEGSGARIAVLNEGDGIAREHLPLL
                     FERFYRVDEAREYRGERHHGLGLSIVKAIAMLHGGEVFVASQDGLATVGFSVG"
     gene            complement(8501..9448)
                     /gene="pip"
                     /locus_tag="LZ605_RS04090"
                     /old_locus_tag="LZ605_04090"
     CDS             complement(8501..9448)
                     /EC_number="3.4.11.5"
                     /GO_function="GO:0004177 - aminopeptidase activity
                     [Evidence IEA]"
                     /GO_process="GO:0030163 - protein catabolic process
                     [Evidence IEA]"
                     /NRPS_PKS="Domain: Abhydrolase_1 (35-296). E-value:
                     5.1e-31. Score: 100.1. Matches aSDomain:
                     nrpspksdomains_LZ605_RS04090_Abhydrolase_1.1"
                     /codon_start=1
                     /gene="pip"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF00561"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1036: alpha/beta hydrolase fold protein"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012511182.1"
                     /locus_tag="LZ605_RS04090"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LZ605_04090"
                     /product="prolyl aminopeptidase"
                     /protein_id="WP_249843917.1"
                     /sec_met_domain="PF00561 (E-value: 2.6e-26, bitscore: 90.8,
                     seeds: 48, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRTLYPAIEPYREFTLPVSDLHTLHVEECGTPDGIAVVYLHGGPG
                     AGISPTHRRFFDPARYRIVLIDQRGSARSTPFGELRDNTTQDLVADIEKVREHLGIERW
                     LVYGGSWGSTLALAYAQAHPERATGLIVRGVFLGREIENRWFAEVDGGARWIFPERWDR
                     YEAHIPVAERGNMIEAYWARLDSPDEATRIAAAQAWLGWEDNAATLQHQVDAESSDDPL
                     DTLAKARIEAHYFRNGIFLEPDQLLHGIDRIRHLPGVIVQGRYDIICPPRSAWDLAKAW
                     PEAQLLMVTSGHSANEAATTDALVRATDAFADRF"
     aSDomain        complement(8561..9343)
                     /aSDomain="Abhydrolase_1"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_LZ605_RS04090_Abhydrolase_1.1"
                     /evalue="5.10E-31"
                     /label="LZ605_RS04090_Abhydrolase_1.1"
                     /locus_tag="LZ605_RS04090"
                     /protein_end="296"
                     /protein_start="35"
                     /score="100.1"
                     /tool="antismash"
                     /translation="AVVYLHGGPGAGISPTHRRFFDPARYRIVLIDQRGSARSTPFGEL
                     RDNTTQDLVADIEKVREHLGIERWLVYGGSWGSTLALAYAQAHPERATGLIVRGVFLGR
                     EIENRWFAEVDGGARWIFPERWDRYEAHIPVAERGNMIEAYWARLDSPDEATRIAAAQA
                     WLGWEDNAATLQHQVDAESSDDPLDTLAKARIEAHYFRNGIFLEPDQLLHGIDRIRHLP
                     GVIVQGRYDIICPPRSAWDLAKAWPEAQLLMVTSGHSAN"
     misc_feature    9638..9651
                     /note="TFBS match to ANR, Anaerobic transcriptional
                     regulator, confidence: weak, score: 19.13"
                     /tool="antismash"
     gene            9706..9831
                     /locus_tag="LZ605_RS23075"
     CDS             9706..9831
                     /codon_start=1
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="LZ605_RS23075"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_012511180.1"
                     /transl_table=11
                     /translation="MNNVLALQSLEIESLEAEAECVVCLSWYSSGLGIDEGSDKA"
     CDS_motif       9706..9765
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence: MNNVLALQSLEIESLEAEAE"
                     /locus_tag="LZ605_RS23075_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       9766..9831
                     /prepeptide="core"
                     /locus_tag="LZ605_RS23075_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class III"
                     /score="1.10"
                     /molecular_weight="2117.3"
                     /monoisotopic_mass="2116.0"
                     /core_sequence="CVVCLSWYSSGLGIDEGSDKA"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MNNVLALQSLEIESLEAEAE"
                     /leader_location="[9705:9765](+)"
                     /alternative_weights="2135.4"
                     /alternative_weights="2153.4"
     gene            10001..12694
                     /gene="lanKC"
                     /locus_tag="LZ605_RS04095"
                     /old_locus_tag="LZ605_04095"
     CDS             10001..12694
                     /GO_function="GO:0004672 - protein kinase activity
                     [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_process="GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /GO_process="GO:0006468 - protein phosphorylation [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="lanKC"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-iv: LANC_like"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-iv: Pkinase"
                     /gene_functions="regulatory (smcogs) SMCOG1030:
                     serine/threonine protein kinase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF038151.1"
                     /locus_tag="LZ605_RS04095"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LZ605_04095"
                     /product="class III lanthionine synthetase LanKC"
                     /protein_id="WP_249843918.1"
                     /sec_met_domain="Pkinase (E-value: 1.7e-14, bitscore: 51.8,
                     seeds: 54, tool: rule-based-clusters)"
                     /sec_met_domain="LANC_like (E-value: 1e-16, bitscore: 58.6,
                     seeds: 47, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSEVTARLYTLADSLHFESPDRYRPTDEYAAIARSRLPSSWTMQA
                     RGFWTTCRPAQSVAASHGWKIHLSSIPENAERTLSAILPVVLEAGVAFKFCSDPFMLGL
                     SLGKGWSRFQVGKFITIYPQDPQQFQALLPQLHQATCDLAGPHVLTDRPYADSTVVYYR
                     YGAHAGVSRPDPYGSLQQGYPLSDGAWQEDVRGPAFRLPPGVIDPVTRAAEAAPQSPQG
                     PITLNARYEVKGVLKFNGTGGIYHGRDTATGRKVVIREVRGFSAADGTDVPNGMVNAIQ
                     REARILQKLSGTGRVPVYVDLFKEWNNWFLVQEQLEAITLWDSAMAFYFADEDQRSRDG
                     FERIRTKIRQIGEALQCVHDHDVVLRDLTRSNVMFTADGEVKFIDLEFAHEIGVDSRWA
                     KGWTPGYASQQQLEAQRPTVQEDHYAFGALILDMITFCASGLDLCRQALLERKLRQVLD
                     DLGLPADLHEIVTGLTLQDVDERWSIARALAHLAKAPAPAPDRLMFPTRAQLLEVAAPA
                     AQTRARIAAVLDGYERYLASTCDLSRSDRLWPAGLQMFMTNPVSLQFGATGVAMFLLQR
                     GGQLQPAVLDWIERGATPQRCPSGLYSGRGGVALLMMCAGRPDTARRLLAEINDDPAAR
                     VLPGLYFGAAGLGLLNLHAWRSLRDPAYLEAAARIGDALLQQGQRGAVGLYWKAGDRTG
                     LGLGDGQSGIALFLTYLGKATGAQRYLNAAADALDFDLAHGLRIAGRTVWPTHVESGPA
                     APASPHTRFGSAGIGMACVRHFVATGSERFREAALDCAHSVRPRVTNKIWQDSGNAGFG
                     EFMLDMAHFLGDERFGHAAFYQAEAILPHAIDCEGGIAFAGPAHYRLCNDFGMGGSGIG
                     VFLDRLQNRRRRLLMLDELLSPAPGA"
     gene            complement(12754..14961)
                     /locus_tag="LZ605_RS04100"
                     /old_locus_tag="LZ605_04100"
     CDS             complement(12754..14961)
                     /GO_component="GO:0019867 - outer membrane [Evidence IEA]"
                     /GO_function="GO:0015343 - siderophore-iron transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_process="GO:0015891 - siderophore transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1051:
                     TonB-dependent siderophore receptor"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019337235.1"
                     /locus_tag="LZ605_RS04100"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LZ605_04100"
                     /product="TonB-dependent siderophore receptor"
                     /protein_id="WP_249843919.1"
                     /transl_table=11
                     /translation="MTVFDLPASPVRPAMAAARLLTPPPRADRRHRVSGLALGLLASFA
                     ALAESAESAPSTLPSVQVQEQRRVTSDYAGGQVAGGGRVGLLGDKDFMDTPFSTVSYTE
                     AFIRDHQARDITEVIAATDPTVFSNGVTGSWSENYAIRGFASSTSDTTFNGLSGMAPFY
                     RTSPEMFERIEVLKGPSALLNGMPPGGSVGGAVNLVPKRAGEQPLLRVSANFASDAQFG
                     THVDVGRRLGTDRQFGIRFNGAWRDGDGAVGKQRKKVQLGSLALDWRGSRARLSADLYS
                     ADDRIDGPARGVGLAPGVAIPRPPRGDTLINPDWAYVDSRDKGAMLRGELDINDSLMAY
                     LAYGTSRTDYRYNGSISAQVLNPAGDFSTVIGQLAFDIRKQSGDAGLRGTFRTGSVGHQ
                     WAANVTHYQHTQNDYGRRSVPGWDWTTHLYHPVWGPAAPFIAPHISHTGLRLDSLGVAD
                     TLSFADERVQLTLGVRRQQVLSETFNVATGARTSRYDESATTPAAALLVKASDNVSVYT
                     NYIEGLSQGATAPMTAANAGDVFAPFRTKQKELGLKLDQGSFAHTFSVYEIKRPSSYTD
                     PVTNIFSFGGEQRNRGLEWGFFGSPLDGVRLLGGLAYVQPKLTRTAGGVNEGRIATAVA
                     QRQAKLGVEWNVPVLQGLTLTGNATAMSKQYISADNRLSVPGRTLFDVGARYSTTLAGR
                     PFALRATVNNVANKAYWGMPLLSSLALGAPRTVLLSATMDF"
     misc_feature    15131..15149
                     /note="TFBS match to HgtR, Hydrogen-dependent regulator,
                     confidence: weak, score: 22.17"
                     /tool="antismash"
     misc_feature    complement(15135..15153)
                     /note="TFBS match to HgtR, Hydrogen-dependent regulator,
                     confidence: weak, score: 20.03"
                     /tool="antismash"
     gene            15202..15804
                     /locus_tag="LZ605_RS04105"
                     /old_locus_tag="LZ605_04105"
     CDS             15202..15804
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1239: TetR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005416676.1"
                     /locus_tag="LZ605_RS04105"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LZ605_04105"
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="WP_249843920.1"
                     /transl_table=11
                     /translation="MSTQPDPTQAPRGRPPTITPERLADIGIRLGLPGLTMATVAAELA
                     VSQAALYKRVANLEALKRLVADAVFQRWQIPRASRDAAGGLQGYLLTFVASLCEVVKAH
                     PGLPPYLLRRSVATTPMLEKIAAHQVHVAEVYGLPIDKARWLLATLAFHCIAGADTIYA
                     IADDEDGQVITDFRQGLRALVIGSLQVLKEDGADRSP"
     gene            15817..16944
                     /locus_tag="LZ605_RS04110"
                     /old_locus_tag="LZ605_04110"
     CDS             15817..16944
                     /GO_function="GO:0019104 - DNA N-glycosylase activity
                     [Evidence IEA]"
                     /GO_process="GO:0036297 - interstrand cross-link repair
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005413564.1"
                     /locus_tag="LZ605_RS04110"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LZ605_04110"
                     /product="crosslink repair DNA glycosylase YcaQ family
                     protein"
                     /protein_id="WP_249843921.1"
                     /transl_table=11
                     /translation="MAWIYNAAMPATPTLDDLRRFAVARTLFAPTTLMAAIRRLGFVQA
                     DPIRAPARAQDLTLRHRVKDYRAGDLERRYARLPVEEDCLVNYGFLPREHLALMHPRVS
                     RRVWDAQTRRRAADVLAFVRERGSVHPREVDQAFAHGRVTNYWGGTSNASTQLLDGMHY
                     RGLLRVQRRDSGTRIYTLAEHAEADASEAAQIERAAALVNLVVRKYAPLPSASLTYLVR
                     LLGYGAPHLAEQTRHALKLARQQLASCTLDGTTWYWPADENPRSRRHAPDEQVRLLAPF
                     DPVVWDRRRFEQLWGWVYRFEAYTPAPKRQYGYYALPLLWHDQVVGWANLSVRDGELAS
                     SVGYAGRSLARDRVFGQALQDELERMRVFLEAAGR"
     gene            complement(16969..18693)
                     /locus_tag="LZ605_RS04115"
                     /old_locus_tag="LZ605_04115"
     CDS             complement(16969..18693)
                     /EC_number="2.7.7.65"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1025: diguanylate cyclase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010485511.1"
                     /locus_tag="LZ605_RS04115"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LZ605_04115"
                     /product="diguanylate cyclase"
                     /protein_id="WP_249843922.1"
                     /transl_table=11
                     /translation="MDEADRLLEIDRLSLLDTPPEPVFDAIVAAARSATGMTMGLISVV
                     AEQRQWFKANIGLEGVSETSRDISFCTHAIEQDTLFEVADTRQDPRFSSNPLVTGGPRI
                     RHYVGIALGSAYGARIGTLCLLDPMPGVLSPSQRELMVHLARVTTQVLEQRSALLAQVG
                     QAKALHRELKRSEDFLERTNRAARVGGWELDLHSNEVRWTRETKHIHGVRGNYQPTLES
                     ALSFYRADSRSIMQSAVQRCIDEGTPWEIQVPMTTADHRDIWVRVVGGRQQVDGHTRLV
                     GAIQDITDERAVLDALEASETRYRRLFHYSLGLICTHTLDGTLTSVNPAAVQSLGFEES
                     QMVGRSLGALMPADRRDAFDAYLARIAAAHTDSGVIELIGADGHRRYWAYHNVLDEEAD
                     PPYVLGHAQDVTALRQQERILRELSQRDPLTHCHNRRYLHRLDALVDANWACLLFDLDH
                     FKQINDLQGHRRGDAVLVEFATFLRRPLAEREVVVRLGGDEFLVVLDAPPARLAALEGW
                     YRQHAAAAPTPFSMGSAEHRPGEALAETIHRADTQLYRTRARIRQQMRPAQAPDSGH"
     misc_feature    complement(18699..18709)
                     /note="TFBS match to HypR, L-hydroxyproline utilization
                     repressor, confidence: weak, score: 18.59"
                     /tool="antismash"
     gene            complement(18834..20024)
                     /locus_tag="LZ605_RS04120"
                     /old_locus_tag="LZ605_04120"
     CDS             complement(18834..20024)
                     /EC_number="3.4.-.-"
                     /GO_function="GO:0004222 - metalloendopeptidase activity
                     [Evidence IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /GO_process="GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF013700.4"
                     /locus_tag="LZ605_RS04120"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LZ605_04120"
                     /product="M23 family metallopeptidase"
                     /protein_id="WP_249843923.1"
                     /transl_table=11
                     /translation="MLRRLHLFPAGIACALHAALLLPALSGAGAASAAPALAPVEARVP
                     FAPSPFNGSDGARHLAYELHISNFYGDTGALAPQGLEVRADTSASPLLQLDAAALSAWA
                     RPAAAEGAPLSIAAGKRLTLFIWLSLPADAPLPHVLSHHIDFTTDKGATVSLDGAAVTV
                     AAQSPPQLGPPLKEGRWLAHEGPGAAQSHHWGSLVAVNGALTIPQRFALDLVGVDAQGR
                     AVHAAPERLQHTRHQDWVGYAAPVIAVAHGVVRDARDGEPEHAPLTAQPEPTSLTEAGL
                     FGNYVVLEIAPGVFASYAHLRKGSIKVRPGQTVQRGQALAELGQSGNSAAPHLHFQLSN
                     SVHFEGSEGIPYVFDRFQYFGPESEAQLFGQGPAWNSPSPQPRRQQLPLNDVVIGF"
     gene            complement(20026..20634)
                     /locus_tag="LZ605_RS04125"
                     /old_locus_tag="LZ605_04125"
     CDS             complement(20026..20634)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014037279.1"
                     /locus_tag="LZ605_RS04125"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LZ605_04125"
                     /product="AprI/Inh family metalloprotease inhibitor"
                     /protein_id="WP_249843924.1"
                     /transl_table=11
                     /translation="MAAVLARTCLSALCCLALPALAQDASFGVGQQTTRTDQTTQTSST
                     QTQSADVSAAGNSGAMTTQTTTQGSSHTESRSESSGMDVEVGFHDRSDDWGHEHRRNEP
                     DVRDGDLFGRWTLGQENGSSCTIELKNNEWFGGYSAYVPAGCPDGFFSANRWLLSGNQL
                     LLTDTNNTVLGRFRASGGGRWSGARESDGARLYLNPTGR"
     gene            complement(20737..21066)
                     /locus_tag="LZ605_RS04130"
                     /old_locus_tag="LZ605_04130"
     CDS             complement(20737..21066)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="LZ605_RS04130"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="LZ605_04130"
                     /product="hypothetical protein"
                     /protein_id="WP_249843925.1"
                     /transl_table=11
                     /translation="MPCNTCLDCAWLWPSHCTSTSPSKSGKWVIIVGGHGLHVGGSSLG
                     RDGLRCIGDQRLGKSIDEERIAGRTLLLRVLVEGLAMRAVRDPDLPPTRVRALLADAIG
                     RVMAD"
     gene            21056..>21109
                     /locus_tag="LZ605_RS04135"
                     /old_locus_tag="LZ605_04135"
                     /pseudo=""
     CDS             21056..>21109
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF024744.4"
                     /locus_tag="LZ605_RS04135"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /old_locus_tag="LZ605_04135"
                     /product="hypothetical protein"
                     /pseudo=""
                     /transl_table=11
                     /translation="MQGIAAQQDGAVLFHCMA"
     misc_feature    complement(21066..21083)
                     /note="TFBS match to HipB, Bacterial antitoxin HipB,
                     confidence: weak, score: 20.89"
                     /tool="antismash"
     misc_feature    complement(21527..21539)
                     /note="TFBS match to MatP, Cell cycle regulator,
                     confidence: weak, score: 19.11"
                     /tool="antismash"
ORIGIN
        1 aagtaggtgc ggttgccggt ggccagcacc accgcggtgg cggtgcccga gaccacattg
       61 gtgcccatga acaacaggtt gtgctgttcc agcaggccgg ccaggccgtc gcccgggtgg
      121 gcaaacttct ctaccggcag cgactcgccg gtcatcgccg cctgtgcgac gaacagatcc
      181 ttggcggtca gcacgcggca gtcggcggga atcatgtcgc cggccgacag cacgatgtgg
      241 tcaccaggca ccagctcgcg gatcggcagg tccaacagcc gcgccgggcc tcggctgtgc
      301 agatgcgcgc cgaagtactg gtcggccaca tcggccgcct cggtgcccgg attgcgtcgc
      361 agcacgcgcg cggtgttgcc gaccagcgcc ttcagccgct cggcggcccg gttggaacgg
      421 ccttcctgca cgaagcggat cagggtggag agcagcacca tcgcaccgat cacgatcgtc
      481 gccttgacgt cctcggtcag ccacgacacg gctgccagca cgctcaacag caggttgaac
      541 ggattgcggt agcactgcca caggtgccgc caccacgcca gcggcttttc gtgatccacc
      601 tcgttggggc cgagcgaggc caagcgtgcc tcggcttcat gcgcgctgag gccatcggca
      661 tgcgaggcca gcgtgtccag caatcgagct tcatcctgct gggcgagggt gaccaggccg
      721 gtggtcagcg tgaaaggtgc agcgtccgcg ctgcccgggc cgaaaccagc ctcgggcatt
      781 gcgcggcggc cgaacagatt gcctgcgcga cggctgcgca ggaaggcatt gaaccaggcg
      841 ttgagcaggc tcatgggaac tcctcgaatg tcagagccgg ccgcggccgg aacacgaacg
      901 gatgggatgg aacagctcag gcgtggcgca tggccagcac ggccggcgac catggctgca
      961 tgtgcaggcg ctggctgccg ccgatgcaca gcggcttcat cgcatcgcgc agcgggtagg
     1021 gcaggtggcg cagcacgttg atgcgctcgc tgatcggcag cagcgacagc gcatcggcca
     1081 ccacgcgtgg cgagcccagc gacagggcgc gggcgaacat gaccggtccg tgctgcagca
     1141 gctggctgcg cagggcggcg acatcgcgct caccgatcag gcggcgcaac gtgatgtaga
     1201 ggatcttgta ggacatgggg cgatctccag gcaggcggcg cctggcgatc ccctgtcact
     1261 caggcaggca gggaccggcg ggcaggcgcc aggaacaggc agcaagcggg cgtgcggggc
     1321 gcatcgcgcc cggcagggtc ggggtccatc tgcgtctcct tgagggaagg ggcgggccgg
     1381 ggttgccctg gccagtggcg ctattgtccg cccctgaatg gggcagtcct agaggcccgt
     1441 gggttagccg ggctatacct tggtatagcc ggctgccggg ccgcgccgga atcgtgatca
     1501 gtgcgaaccg ctggtgttcc tgcacacgtc gtactcgccg cgggtcagcg tcttgtcacg
     1561 gtcggtatcg caggcgtgca ggcgttgtgc ccaatcgggt gccaccgcat cgacctcggc
     1621 gagggtgacg atgccgtcct tgtccttgtc cagcgattca tacggcggaa tcagctttac
     1681 ctgggttacc tcttcggcgg cggtcttgct gggctcctgt ggcttggaac acgcccccag
     1741 cagcaggccg gctgcaacaa cgagggcggc gggaacgaaa cggaaaccgg tcatggcgtg
     1801 ctcctgttgg cggggggcag ccaccacggc gcccaccgcc ggatgatcgg cgccgatctg
     1861 taaggggtac gcgaagaatc gtgcgctgcc ggcgctggca ttgggacccc gttcacccgc
     1921 gcctgcgcac agctatagga gatccacctg tcgaaattgt caggcaggcg acagcagggt
     1981 gcccgagccg gccggagagg atggcaacag gcccgcgcag cccccgcgcc ggcaccggca
     2041 tggaccccca caatgcgaat tccgctgctg tccgcacgat tgcgtcgtcg tcacttggct
     2101 ctgggggcgc tgctgctggt cgtgctctcg ctgctgatgc tgttccatgg tgtgtcgcgc
     2161 ggagatgcgc aaccggccag cgcgccaccg ccggtgccgg tggtcaccgg ccgggtcgaa
     2221 caacaggaca tcgcccattg gcgaaatggc ctgggcaccg tgcagtcgct gcagagcacg
     2281 gtgttgcggc cgcaggtgga tggcgtgctg accgaggtgc tgttcgagga aggtcagaag
     2341 gtacgcaagg ggcagctgct ggcacgcatc gatgatcggg cgatccgcgc cgatctgggt
     2401 ggggcgcagg ccgcggtagc ccgtgatcgg gccacgctgg atgccgcgcg ctccgatctg
     2461 gcgcgcctgc agcacctgtc cagcgaccag ctggtgtcgc ggcagatgct ggagcagcag
     2521 gccgccaccg tgcagcagct gcaggccacc gggcgtggca accaggcggc ggtggatgcc
     2581 gcccaagtgc agctgtcgta tacccgcatc ctggcgccga tggacggccg catcggcctg
     2641 cgtcaggtcg acccgggcaa cctggtgcgc gccagcgata cccagggcct ggtgaccgta
     2701 cagcagaccg atccaatctc ggtggtcttc gcgctgccgc aggacacgct accgcagctg
     2761 cgccaggccc ttgcggccgg ggtggtgccg gtgcaggcgc tggaccgcga tggcggccag
     2821 ctgctggccg aaggcagttt gcaggtgatc gacaaccagg tggaggaaac ctccggcacc
     2881 gtgcgcctgc gcgcacgctt tgccaatgcc gatgatcgcc tgtggccagg ccagctggtc
     2941 agcgtgcgcg tgcgtaccgg gcagagcgcg gccacgctgg tggtggacgc cgccgcgatc
     3001 cagcgcggca tcgagggcag ttttgtgtat cgggtggtgg ccgatggcag cgtcgaagtg
     3061 ctgccggtca gcgtcggtga atccgagaac ggcaaagtgg cggtgcaggg cgagctgcgg
     3121 gtgggcgatg tgatcgtccg tgatggccag tcgcggttgc gcccgggcgt ggtggttgcc
     3181 gaggccgcgt ctgcgccggc agccaagcgc ggggccgcgc catgagcgcg cgggtttcgc
     3241 tgtccagctg gttcgtcagg catccggtgg ccaccacgct gctgacgctg gcggtgatcc
     3301 tgctcggcgt ggccgcgttg ccgcagttgc cggtggcgcc gctgccagaa gcggaatttc
     3361 ccaccatccg ggtcaatgcc aacctgcccg gagccagcgc cgaaacgatg gcctcggcgg
     3421 tcgccacgcc gttggagacg cagctgaccg gcgtgcccgg catcatcgag atgacctcca
     3481 ccagtgcgct gggcagcacc tcgatcaccc tgcagttcga tctggaaaag gacatcgaca
     3541 ctgccgcgca ggaagtgcag gcggcgatca atgctgccgc cgggcgcctg cccagcgatc
     3601 tgccgaacct gccgacctgg cgcaaggtca acccggccga cagtccgatc ctggtgctca
     3661 gcgtggtctc ggcgcagatg tcgatgaccg aactgagcga tctggctgaa agccggctgg
     3721 cgcgctcgat cagccagatc agtggcgtgt ccgaggtcaa catcgtcggc cagcagcgcc
     3781 cggccatccg catccaggcc cagcccgagc ggctggcggc gatgggcatg accctgtcgg
     3841 atctgcgcgg cgtggcccag aacgccagcc tcaaccaggc caagggtgcg ctgatgggcg
     3901 gccagcgcac gtccaccttc gaggccaacg accagttgtt cgacgcgcag gactatcggc
     3961 agctggtggt ggcctaccgt gacggctcgc cggtaacgct cggcgatgtg gcgcaggtgg
     4021 tcgacggtgc cgagaacgcg tatgtgcagg cgtggccgaa cgggcagccg ggcgtgggcc
     4081 tgatcatcag ccgccagcca ggggccaaca tcgtgcgcac caccgatgcg gtgctggccg
     4141 cgttgccggc gctgcgtgcc aatctgccgg ccagtgtcga cgtggaggtg ctcaatgacc
     4201 gcacacgcac catccgtgcc tcgctgcatg aagtggaagt gaccctggtg ctgaccatcg
     4261 tgctggtggt gctggtgatg gggctgttcc tgcgccagct gtcggccacg ctgatcgtcg
     4321 gtgcggtgct ggtggtcgcg ttggtggcca cgttcgcggc gatgtacgtg gccggtttca
     4381 gcctgaacaa cctcaccctg gtcgcgctgg tggtcgcggt cggcttcgtg gtggacgatg
     4441 cgatcgtggt ggtggagaac atacaccgcc atcgcgaggc cggattggga ccgatggaag
     4501 cggcgctgaa gggcgccggc gagatcggct tcaccgtggt ctcgatcagc ctgtcactga
     4561 tcgccgcgtt catcccgttg ctgttcatgg gcggcgtggt cggccgcctg ttcgccgagt
     4621 tcgcgctgac catcacggtg gcgatcctga tttcgatcgt ggcctcgctg acgctggcgc
     4681 cgatgatggc tgcgcacctg atgaaacgca tgcccgccca tcgtgacggc caggacacgc
     4741 tggccggtcg cctgttggcc ggctacgacc gcagcctgca atgggcgctg ggccatcaac
     4801 gtacggtgct gctcggcttc ggcgccacag tggcggtggc ggtggcctcc tacgtgatga
     4861 tccccaaggg cttcttcccg ttgcaggaca ccgccttcgt gatcgccacc accgaggcgg
     4921 cgcaggacat cggctacgag cagatggctg ccaagcaccg gcagctggcc gccatcgctg
     4981 ccgaggaccc ggcgttgcag gcctacaatc atgcggtggg cgccaccggc ggcagccaga
     5041 ccctgtccaa cggccgcttc tggttcgtgc tgaaggatcg cggcgaccgc gatgtggacg
     5101 tgcatgcgtt catcgaccga ctgcgcgcga agatggccag cgtgccgggc atcaccgtgt
     5161 acatgcgcgc cgcgcaggac atcaatctgg gcgcagggcc ggcgcgcacg cagtaccagt
     5221 acgcgttgcg cggacaggac agtcgcgaac tgtcgcgctg ggccgaacag ctgaccgaac
     5281 gcctgcgtgg cctgccgcag ctgcgcgatg tatccaacga ccagcaggtc ggcgccagtg
     5341 tcacccgctt gcagatcgat cgcaccgctg cggcgcggtt cggattgacc gccaacgaca
     5401 tcgaccaggt gctctacgat gcgttcggcc agcgccagat caacgagttc cagaccgaga
     5461 ccaaccagta ccgggtgatc ctggagatcg cgccgggcat gctcggcgag gtcgacgcgc
     5521 tgtcctactt ccacctgcgc tcgccattga ccgggcagat ggtgccgctg tcggcggtgg
     5581 cccaggtaca gccgccgggc aacgggccgc tgtcgatcag ccacaacggc atgctgccag
     5641 cggtgaatct gtcgttcaat ctggccccgg gtgtatcgct gggcgaggcg gtgcagctgg
     5701 ttgaacaggc ccaggtccag ctgggcatgc cggccagcat cagcggccgc ttccagggca
     5761 ccgcgcaggc gttccaggaa tcgctggcca gccagccatt gctgatcctg gccgcgctgc
     5821 tggcggtcta catcatcctc ggcgtgctgt acgagagctt cgtgcacccg ctcacgatcc
     5881 tgtccacgct gccttcggcc ggcatcggcg cggtgctgat gctgtggctg tgggggctgg
     5941 agttttcgat catggcgttg atcggcatcg tgctgttgat cggcatcgtc aagaagaacg
     6001 gcatcctgat ggtcgacttc gcgctggacg cgcaacgcaa ccgcggattg tcgccgttgc
     6061 aggcgatcca cgaggcctgc ctgacccgtt tccgcccgat catgatgacc acgctggccg
     6121 cgctgctggg cgccattccg ttgatgatcg ggtttggcac cggttcggag ctgcgccagc
     6181 ctctgggcgt ggcagtggtc ggcggcctgc tgatcagcca gctgctgacc ctgtacagta
     6241 ccccggtgat ctacctggcc ctggaccggc tgttcctgca acgtcgtcgc gagcgcaggg
     6301 cagaggaagg tgccgcgctg acggagcccg gatgaaactg ctgattgtcg aggatgagag
     6361 caagaccgcc cattacctgc gcaccggcct gggtgagcag ggctgggcgg tggacctggc
     6421 tgccgacggc gtgaccggcc tgcacctggc ccgcgaattc gactacgacg tgatcgtgct
     6481 ggacgtgatg ctgccgggca tggatggctt caacgtgctg cgcgagctgc gccgcagcaa
     6541 gcagaccccg gtgatcatgc tgaccgcgcg tgatcgcgtg gatgaccgcg tgcacgggct
     6601 ggggcagggc gccgatgact atctggtcaa gccgttctcg ttcatcgagc tgctggcacg
     6661 gctgcaggca ctggtgcgac gtggccggca gcaggagccg accgaactgc aggtgggtga
     6721 cctgcaggtg aacctgctgg cacgccgcgc ctatcgtgac ggcgcacgcc tggacctgac
     6781 cggcaaggag ttcgcgctgc tggccctgct ggcgcagcgg cgaggacaga tcctgtccaa
     6841 gacggtgatt gccgcgcagg tctgggacat caacttcgac agcaatacca acgtggtgga
     6901 agtggcgatc aagcgcttgc gcggcaagct cgatggccca taccccagca agctgctgca
     6961 caccgtgcgc ggcatgggct atgtgctgga ggtgcgcgaa gacgaggacg ggccgcgatg
     7021 aggtggtcga tcgcgcagcg cctgtcggcg atgttcgctg tggccgcgct gctggtgttc
     7081 accctgctcg gcatcggtgt gtatggcgtg ctcgaacggc aggtcgtgcg ttatcagcat
     7141 gccgagctgc agaccaagct gcacgcggtg agcggcagcg tggcgatgtg cgatacccgt
     7201 gagcgctgga ccaaggtgcg cgagaaggtc ggcaacctga tttctggtga ccgcgacaca
     7261 ttggtgtggg cctggagcga tgacccgacc ttccgtatcg gcagtgcgca gccgcaggta
     7321 caaccgcccg gcagtcatga cgatggcatg gggaccctgc agcgtgaggg tgcgcacccg
     7381 ctgcgcacgc tctacgagca cgtgcccggc aaaggcgtac ggccgccggt ggacctgtgg
     7441 atcggcatcg actccgagcc ctatacgcat gcactgcagc ggtttgctgt agcactgtgg
     7501 gtggccggtg tgctgggcgt gctgctggtg gccggcctgg gctactggat cgcgcggttg
     7561 ggattggcgc cattgcgggc gctgtccgac gaagcgcgct cactcagtcc ccagcggctg
     7621 tcgcagcggc tggacactgc ggggctgccg gccgagctgg gtcacctgac cggcgccttc
     7681 aatggcgcgc tggatcgact ggaagccgca tatacgcggc tggatgcctt caatgcggac
     7741 gtggcgcatg aactgcgcac gcctctggcc aacctgatgg gccagaccca ggtcgcgctg
     7801 tcgcggccgc gcgataacgc cgacctgcag gaagtgatgc agtcgaatct ggaagagctg
     7861 gagcgcctgc gcgccatcgt caacgacatg cttttcttgt cgcgtgccgg gcagggtgac
     7921 atcgccatgg acacccgcac cgtgtccctg gccgaggagg tggccacggc cggggagttc
     7981 ctcgagttgc tgttcgagga ggcggggctg accctgcgca ttgaaggtga cgccagcgca
     8041 cgcatcgatc cgtcgctgct gaggcgtgca ttgaccaacc tgctgcacaa cgccgtgcag
     8101 cacgcgcggc ctggcagcgt ggtgcgggtg cagctgcagg ccgaaggcag cggtgcccgc
     8161 attgcggtgc tgaacgaggg cgacggcatc gcccgcgaac acctgccgtt gctgttcgag
     8221 cgcttctacc gggtggatga agcccgcgag taccgaggcg agcgtcacca cgggctgggc
     8281 ctgtccatcg tcaaggccat cgccatgctg cacggcggtg aagtattcgt ggccagccag
     8341 gacgggctgg ccacggtggg gttcagtgtc ggctgaagga atcccgctgg gtagagtcga
     8401 ccagtgctcg accctgccag gagcggggcg ccagccatgt ccccggccga ttcttcacga
     8461 gttctccgaa gatccgcggc tgttcgccct cgatgccccg tcagaatctg tccgcaaacg
     8521 catcggtggc gcgcaccagt gcatcggtcg tggccgcttc attggcgctg tggcccgagg
     8581 tcaccatcag cagctgcgct tccggccagg ccttggccag atcccaggcg ctgcgcggcg
     8641 ggcagatgat gtcgtagcgc ccctgcacga tcacgcccgg caggtggcgg atgcggtcga
     8701 taccgtgcag cagctggtcc ggctccagga aaatgccatt gcggaagtag tgcgcttcga
     8761 tccgtgcctt ggccagcgta tccagcgggt catcgctgga ttcggcgtcc acctggtgtt
     8821 gcagcgtggc ggcgttgtct tcccagccca gccaggcctg ggccgcggcg atgcgggtcg
     8881 cctcatccgg gctgtccagc cgcgcccagt aggcctcgat catgttgccg cgctcggcca
     8941 cgggaatatg ggcctcgtag cggtcccagc gctccgggaa gatccagcgc gcaccgccat
     9001 cgacttcggc gaaccagcga ttctcgatct cgcggccgag gaacacgccg cgcacgatca
     9061 ggccggtggc ccgctcggga tgcgcctgcg cataggccag cgccagcgtt gagccccacg
     9121 agccgccgta gaccagccag cgctcgatgc ccaggtgctc gcgcaccttc tcgatatcgg
     9181 ccaccagatc ctgcgtggtg ttgtcgcgca gttcgccgaa cggggtggaa cgtgcgctgc
     9241 cgcgctggtc gatcagcacg atgcggtagc gcgccgggtc gaagaagcgt cgatgagtgg
     9301 gcgagatgcc agcgccgggc ccaccgtgca ggtacaccac cgcgatgcca tcgggcgtgc
     9361 cgcattcttc cacgtgcagg gtgtgcagat cgctgaccgg cagcgtgaac tcgcggtagg
     9421 gctcgatggc gggatacagg gtgcgcatgg caggcgtctc acgaacgggg ccgccagcat
     9481 agcgccccca gcgtgccagc acagggcatg ccacgttgca gatgctgtaa atgcactggt
     9541 cggtgcgcgt agacacggtg cgatgcatgc gcaactgaaa attgctgcaa gcgcgtttga
     9601 cagcatttgg agtcgcgctt ataagtttca ggcggcgttg acaaggatca atcacgacgc
     9661 cgcattcagc agtgttcatc tcccaacaaa ataaggaagt gaagaatgaa caacgtactt
     9721 gctctgcagt cgctggaaat cgagtcgctg gaagctgaag ccgagtgtgt ggtctgcctg
     9781 tcctggtaca gctcgggcct gggcatcgac gaaggttcgg acaaggcgta gtccatcggg
     9841 ctgccctgaa ccttctgcca ccggccggcg tccgccgcgc cagtggcgaa gtcttcaatg
     9901 gttgaagtcg ctgcgccgtt cacctgggtg gacggtgcag tctgtcggcg cgtgcgatgc
     9961 ggacacggtg gatcccgccg tgtcgacaag gaggtgtgga gtgagtgagg tgacggcacg
    10021 tctgtacacg ctggctgaca gcctgcattt tgaatcgccg gaccgctacc ggccgaccga
    10081 tgagtatgca gcgatcgcgc gcagccgctt gccatccagc tggacgatgc aggcgcgggg
    10141 cttctggacc acctgtcgtc ccgcacagag cgtagcggcc agccacgggt ggaagatcca
    10201 tctgtccagt attcctgaaa acgccgaacg cacactgtct gcgatcctgc cggtggtgct
    10261 ggaggccggc gtggcgttca agttctgctc cgatcctttc atgctcgggc tttcgctggg
    10321 caagggatgg tcgcgcttcc aggtgggcaa gttcatcacg atctacccgc aggacccgca
    10381 gcagttccag gcgttgctgc cacagctgca tcaggccacc tgtgatctgg ccggcccgca
    10441 tgtgctgacc gatcgcccct acgccgacag cacggtggtc tactaccggt atggcgcgca
    10501 tgccggcgta tcgcggccgg atccctacgg cagtctgcag cagggctacc cgctcagtga
    10561 cggcgcatgg caggaagacg tgcgtggccc ggcattccgg ctgccgcccg gcgtcatcga
    10621 tccggtcacc cgcgccgccg aagcggcgcc gcagtcaccg caggggccga tcaccctcaa
    10681 cgcccgctat gaagtgaagg gggtgctcaa gttcaacggc accggcggca tctatcacgg
    10741 gcgtgatacc gccaccgggc gcaaggtcgt catccgcgag gtgcgtggct tttccgccgc
    10801 cgatggcacc gatgtaccca acggtatggt caatgcgatc cagcgcgagg cccggatcct
    10861 gcagaaactg tccgggaccg gacgggtgcc ggtatatgtg gacctgttca aggaatggaa
    10921 caactggttc ctggtccagg agcagctgga ggcgatcacg ctgtgggaca gtgcgatggc
    10981 gttctacttc gccgatgagg atcagcggtc gcgcgacggt tttgagcgta tccgcacgaa
    11041 gatccgccag atcggcgagg cgctgcagtg cgttcacgac cacgacgtcg tgctgcgcga
    11101 cctgacccgc agcaacgtga tgttcaccgc tgatggggaa gtgaagttca tcgatctgga
    11161 gttcgcgcac gagatcggtg tcgactcgcg ctgggccaag ggctggacgc cgggctacgc
    11221 ctcgcagcag cagttggaag cgcagcgccc tacggtgcag gaggatcact acgcgttcgg
    11281 cgcgctcatt ctggacatga tcaccttctg tgcctccggc ctggatctgt gccgacaggc
    11341 cctgcttgag cgcaagctgc gccaggtgct ggatgatctg ggcctgcccg ccgatctgca
    11401 cgagatcgtg acgggcctga cgcttcagga cgtggatgaa cgctggagca tcgcgcgtgc
    11461 gttggcgcac ctggccaagg cgccggcgcc cgcaccggac agattgatgt tcccgacacg
    11521 cgcgcaactg ctggaggtgg ccgcgccggc agcgcagacg cgagcgcgca ttgctgccgt
    11581 actggacggc tacgaacgct acctcgcctc gacctgcgat ctctcacgca gcgatcgcct
    11641 gtggccggcg ggcctgcaga tgttcatgac caacccggtc tcgctgcagt tcggcgcgac
    11701 cggcgttgcg atgttcctgt tgcaacgggg cggccaacta cagccggctg tgctggactg
    11761 gatcgaacgc ggcgccaccc cgcaacgatg cccgagcggc ctgtactccg gccgcggcgg
    11821 cgtcgccttg ctgatgatgt gcgcaggccg cccggacacg gcgcgccgcc tgctggccga
    11881 gatcaacgat gacccggccg cgcgggtgct gcccgggctg tacttcggcg ccgcgggact
    11941 gggcctgctg aatctgcacg cctggcggtc gttgcgcgac ccggcctacc ttgaggcggc
    12001 tgcgcgcatc ggcgatgcgt tgttgcagca ggggcagcgc ggtgccgtcg gcctgtactg
    12061 gaaggcaggg gaccgcaccg gcctggggct gggcgatgga cagagtggta tcgcgctgtt
    12121 tctcacctat ctgggcaagg cgaccggcgc gcagcgctat ctcaatgccg ccgccgatgc
    12181 actggatttc gatctcgccc atggcctgcg cattgccggg agaacggtat ggcccacgca
    12241 cgttgaaagc ggaccggccg cgccggccag cccgcatacc cgtttcggat cggcaggcat
    12301 cggcatggcc tgcgtgcgtc acttcgtcgc taccggcagt gagcgtttcc gcgaggcggc
    12361 gctggactgc gcgcattcgg tgcggccacg ggtcaccaac aagatctggc aggacagcgg
    12421 caatgccggc ttcggtgagt tcatgctgga catggcgcat tttctcggcg atgagcgctt
    12481 cggccatgcc gccttctacc aggccgaggc gatcctgcca cacgcgatcg actgcgaggg
    12541 aggcatcgcc tttgccgggc cggcacacta tcgcctctgc aacgacttcg gcatgggggg
    12601 ctccggcatt ggtgtgttcc tggatcgact gcagaaccgc cgccgtcgcc tgctgatgct
    12661 ggatgaactg ctgtcgccgg cacctggcgc atgatcccgc gacgttgccg gtgcggcgcc
    12721 cggcaacgtc gcgtcctgga cgggccaggc gcctcagaaa tccatcgtgg ccgagagcag
    12781 caccgttctc ggcgcaccca gtgccaggct cgacagcaac ggcatgcccc agtacgcctt
    12841 gttggccacg ttgttcaccg tggcacgcag cgcaaacggc cggcccgcca gcgtcgtgct
    12901 gtagcgcgcg cccacatcga acagcgtgcg gcccggcacc gacaggcggt tgtcggcact
    12961 gatgtactgc ttggacatgg ccgtcgcatt cccggtcagg gtcagcccct gcagcaccgg
    13021 cacattccat tccacgccca gcttggcctg gcgctgggcc acggcagtgg cgatgcggcc
    13081 ctcattcacg ccgccggcgg tacgggtcag cttcggttgc acataggcaa ggccgcccag
    13141 caggcgcacg ccgtccagcg gtgaaccgaa gaagccccat tccaggccac ggttacgttg
    13201 ctcgccacca aacgagaaga tgttggtgac cgggtcggtg tagctgctcg gacgcttgat
    13261 ctcgtacacg ctgaaggtgt gcgcgaaact gccctggtcc agcttcaggc ccagctcctt
    13321 ctgcttggtg cggaagggtg cgaacacatc gccagcgttg gccgcggtca tcggtgcggt
    13381 ggcgccctgg ctgaggcctt cgatgtagtt ggtgtagacc gagacgttgt cgctggcttt
    13441 caccagcaac gcggccgccg gggtggtggc gctttcgtca tagcgcgagg tgcgcgcacc
    13501 ggtggccacg ttgaaggtct cgctgagtac ctgctgacga cgcacgccca gcgtcagctg
    13561 cacgcgctca tcggcgaaag acagggtgtc ggccacgcca aggctgtcca ggcgcagtcc
    13621 ggtgtgcgag atgtgcggcg cgatgaacgg cgcggccggc ccccacaccg ggtggtagag
    13681 gtgggtggtc cagtcccagc ccggcacgct gcggcggcca tagtcgttct gggtgtgctg
    13741 gtagtgggtc acattggcgg cccactgatg gccgacgctg ccggtacgga acgtgccgcg
    13801 caggccggca tcaccggact gcttgcggat atcgaacgcc agctggccga tcactgtgct
    13861 gaaatcgccg gccgggttga gcacctgtgc gctgatcgag ccgttgtagc ggtagtcggt
    13921 cctgctggtg ccataggcca ggtaggccat caggctgtca ttgatgtcca gctcgccgcg
    13981 cagcatcgcg cccttgtccc ggctgtccac gtacgcccag tccgggttga tcagggtatc
    14041 gccgcgcggc gggcgcggaa tcgccacccc cggggccaga ccgaccccgc gcgccgggcc
    14101 gtcaatgcgg tcgtcggcgc tgtacagatc ggccgacagg cgcgcacggc tgccgcgcca
    14161 gtccagtgcc agcgacccca gctgcacctt cttgcgctgc ttgccgacgg cgccgtcgcc
    14221 atcacgccag gcgccgttga agcggatgcc gaactgcctg tcggtgccca gccggcggcc
    14281 gacgtccaca tgggtgccga actgcgcatc ggaggcgaag ttggcactga cccgcagcag
    14341 cggctgctca ccggcacgct tgggcaccag gttcaccgcg ccgcccaccg agccgcccgg
    14401 cggcatgccg ttgagcaacg ccgacgggcc cttcagtacc tcgatgcgct cgaacatttc
    14461 cggcgaggtg cggtagaacg gcgccatgcc gctgagaccg ttgaaggtgg tgtcgctggt
    14521 actggaggcg aagccacgga tggcgtagtt ctcgctccac gagccggtga cgccgttgct
    14581 gaacaccgtt gggtcggtgg cggcgatgac ctcggtgatg tcccgggcct ggtggtcgcg
    14641 gatgaacgct tcggtatagc tgaccgtgct gaacggtgtg tccatgaagt ccttgtcacc
    14701 gagcaggccg acacggccgc cgccggccac ctgtccgccc gcgtagtcgc tggtgacccg
    14761 ccgctgttcc tgcacctgca ccgagggcag ggtggacggt gccgattcgg cagattcggc
    14821 caacgcggcg aacgaggcca gcaggcccag cgcgaggccc gagacgcggt ggcgccggtc
    14881 cgcgcgcggc ggaggtgtca gcagccgcgc agcggccatg gccggacgga cgggcgaagc
    14941 gggtagatca aacacggtca tgccaggttc ctgtagatcg caggcgcgaa cgcgcctggc
    15001 gcgctgccat cggcaagcac ggggaggggg cgcagcgcag ggttgttggc tgggtgggga
    15061 cctggcggga gatgagccac cggctcgatt cgggtgtggg ccacggtggc gagccgggcg
    15121 cacttcaatt tagttgagta cagtaaacta aatcacagga agcggacaag agggtccctt
    15181 tgctgtcacc ctgacaacgc tatgagtacg caacccgatc caacacaggc gccccgtggc
    15241 cggccgccca ccatcacccc cgagcgtctg gccgacatcg gcatccgcct ggggctgccc
    15301 ggcctgacca tggccaccgt tgccgccgaa ctggcggtga gccaggccgc gctgtacaag
    15361 cgcgtggcca atctggaggc gttgaaacgg ctggtggccg atgccgtgtt ccagcgctgg
    15421 cagatcccgc gcgcatcgcg tgatgccgcg ggcggactgc agggctacct gctgacgttt
    15481 gtggcgtcgc tgtgcgaggt ggtgaaggcg catcccgggc tgccgccgta tctgctgcgg
    15541 cgttcggtgg cgaccacgcc gatgctggaa aagatcgccg cccaccaggt gcatgtggcc
    15601 gaggtgtacg ggctgccgat cgacaaggcg cgttggttgt tggcgaccct ggcgttccac
    15661 tgcatcgccg gtgccgacac catctacgcg atcgccgacg atgaggatgg ccaggtcatc
    15721 accgacttca ggcagggtct gcgtgcgctg gtgatcgggt cgttgcaggt cttgaaagag
    15781 gacggcgcgg accgatcgcc gtgaccccat ccacgcatgg cgtggatcta caatgcggcc
    15841 atgcctgcca cgcccaccct cgatgacctg cgccgcttcg ctgtggcgcg caccctgttc
    15901 gcacccacca cgctgatggc ggcgatccgg cggctcggct tcgtacaggc cgacccgatc
    15961 cgcgccccgg cgcgtgcgca ggacctgacc ctgcgacacc gggtgaagga ctaccgcgcg
    16021 ggagatctgg agcggcgcta cgcgcgcctg ccggtggaag aagactgcct ggtcaactac
    16081 ggtttcctgc cgcgtgagca tctggcgctg atgcatccgc gcgtgtcccg gcgcgtgtgg
    16141 gatgcgcaga cccggcgccg tgcagccgat gtgctggcct ttgtacgcga acgcggcagt
    16201 gtgcacccgc gtgaagtcga tcaggccttc gcgcatggcc gggtgaccaa ctactggggt
    16261 ggcaccagca atgccagcac ccagttgctt gacggcatgc attaccgcgg actgttgcgc
    16321 gtgcagcgcc gcgacagtgg cacgcgcatc tacacgttgg ccgaacacgc cgaggccgat
    16381 gccagcgagg ctgcgcagat cgagcgcgcg gcggcgctgg tcaacctggt ggtgcgcaag
    16441 tacgcgccgc tgccgtcggc cagcctgacc tatctggtgc gcctgctggg ctatggcgca
    16501 ccacacctgg ccgagcagac ccggcacgcg ctgaaactgg ccaggcagca acttgccagt
    16561 tgcacgctgg acggcaccac gtggtactgg ccggcggatg agaatccacg ctcccgccgc
    16621 cacgcgccgg acgagcaggt gcgcctgctg gcaccgttcg atccggtggt gtgggatcgc
    16681 cgccgcttcg agcagttgtg gggctgggtc taccggttcg aggcgtacac gcctgcaccc
    16741 aagcgccagt acggctacta cgccctgccg ctgttgtggc acgaccaggt ggtgggctgg
    16801 gccaatctca gcgtgcgcga cggcgagctg gcctcgagcg tgggctatgc cgggcgatcg
    16861 ctggcgcgcg atcgggtgtt tggccaggcg ttgcaggacg agctggagcg gatgcgcgtg
    16921 ttcctggagg cggccgggcg ctagcaccgg cggcagcgga ggcggcgttc agtgcccgga
    16981 atcgggcgcc tgcgccggac gcatctgctg gcggatgcgg gcgcgtgtcc ggtacagctg
    17041 ggtatctgcg cgatggatgg tctcggccaa agcctcgccc gggcggtgct cggcgctgcc
    17101 catcgagaac ggcgtgggtg cggccgcggc atgctgccgg taccagcctt ccagcgcggc
    17161 caggcgcgcg ggcggggcat ccagcacgac caggaactca tcgccgccca gccgcaccac
    17221 gacttcgcgt tcggccagcg gccggcgcag gaaggtggcg aactccacca gcaccgcgtc
    17281 gccgcgccga tgcccctgca gatcgttgat ctgcttgaaa tggtccaggt cgaacagcag
    17341 gcaggcccag ttcgcgtcaa ccagggcatc gagccgatgc aggtagcggc ggttgtggca
    17401 gtgggtcagc gggtcgcgct gggacagctc gcgcaggatg cgctcctgtt ggcgcagcgc
    17461 agtgacgtcc tgcgcatgcc ccagcacata gggcggatcg gcctcttcgt cgagcacatt
    17521 gtggtaggcc cagtagcggc gatggccatc ggcgccgatc agctcgatca cgcccgaatc
    17581 ggtgtgcgcc gcggcgatgc gtgccaggta ggcgtcgaac gcgtcgcggc gatctgcggg
    17641 catcagcgcg ccgaggctgc gcccgaccat ctggctctcc tcgaaaccca gcgactgcac
    17701 ggccgccggg ttcaccgagg tcagcgtgcc gtccagggta tgcgtgcaga tcaggcccag
    17761 gctgtaatgg aacaggcgcc gatagcgtgt ttcgctggct tccagcgcat ccagcacggc
    17821 gcgctcgtcg gtgatgtcct ggatcgcgcc gaccagacgt gtgtggccat cgacctgctg
    17881 ccgcccaccc accacgcgca cccagatgtc gcgatggtcg gcagtggtca tcggcacctg
    17941 tatttcccag ggtgtgcctt cgtcgatgca gcgttgcacc gcgctctgca tgatgctgcg
    18001 gctgtcggcg cgatagaacg acagtgctga ttccagtgtc ggctggtaat tgccgcggac
    18061 gccgtggata tgcttggttt cgcgggtcca gcgcacctcg ttgctgtgca ggtccagctc
    18121 ccagcccccc acgcgcgcgg cgcggttggt gcgctcgagg aaatcctcgc tgcgcttgag
    18181 ttcgcgatgc agtgccttgg cctggccgac ctgtgccagc agtgcgctgc gctgttccag
    18241 cacctgggtg gtgacccgcg ccaggtgcac catcagttcg cgctgcgagg gtgacagcac
    18301 gccgggcatc gggtcgagca ggcacagggt gccgatgcgg gcgccgtagg ccgagccgag
    18361 cgcgatgccg acgtagtggc ggatgcgcgg gccgccggtg accagcggat tgctggagaa
    18421 gcgggggtcc tggcgcgtat cggcgacttc gaacagggtg tcctgctcga tggcatgggt
    18481 acagaacgag atgtcgcgcg aggtctcgct gacaccttcc aggccgatgt tggccttgaa
    18541 ccactggcgc tgctcggcga ccaccgagat cagccccatg gtcattccgg tggcggaacg
    18601 ggccgctgcg acgatggcgt cgaacaccgg ctccggcggc gtatccagaa ggctcagtcg
    18661 gtcgatttca agcagtcggt cggcttcgtc catggtgcgt gacagggcag gggcgtgggc
    18721 gggaggctgc gacggcaccg gcgatgctag cgccgccgga gttatctagt gccaagcacg
    18781 ggtgatgcca gtgtgaggcg agggcggtct ttggtccgcg cgcatcgcct cgatcagaag
    18841 ccgatcacca catcgttgag cggcagctgc tgccggcgtg gctgcggcga cgggctgttc
    18901 caggctggcc cttgcccgaa cagctgcgcc tccgattccg gaccgaagta ctggaagcga
    18961 tcgaagacat agggaatccc ctccgagccc tcgaagtgca cgctgttgct cagctggaaa
    19021 tgcaggtgcg gagccgccga gttacccgat tggccgagtt cggccagggc ctgcccgcgc
    19081 tgcaccgtct gcccgggcct gaccttgatg ctgcccttgc gcagatgggc atagctggcg
    19141 aacacgccgg gcgcgatttc cagcaccacg tagttgccga acaggccggc ttcggtaagc
    19201 gatgtgggct ccggctgcgc ggtgagcggt gcatgctccg gttcgccatc gcgggcatcg
    19261 cgcaccacgc cgtgggccac cgcgatgacc ggtgccgcat agccgaccca gtcctggtgg
    19321 cgcgtgtgtt gcaggcgctc gggagcggca tgcaccgcac ggccctgtgc gtccaccccc
    19381 accagatcga gcgcgaaccg ctgggggatg gtcagcgcac cgttcaccgc caccaggctg
    19441 ccccagtgat gcgactgcgc cgccccgggg ccttcgtgcg cgagccagcg cccttccttc
    19501 agcggagggc ccagctgcgg cggtgactgc gcagcgacgg tcaccgcagc gccgtcgagg
    19561 gaaacggtgg cgcccttgtc cgtggtgaaa tcgatgtggt ggctgagaac gtgcggaagc
    19621 ggtgcatcgg ctggcaggct cagccagatg aacagggtga ggcgcttgcc ggcagcgatc
    19681 gacaacggtg cgccttctgc ggcggccgga cgcgcccatg ctgacaatgc cgcagcatcc
    19741 agctgcagca acggcgatgc cgaggtgtct gcacgcacct ccagtccctg cggtgccagc
    19801 gcgccggtat ccccgtagaa gttgctgatg tgcagttcat aggccaggtg gcgcgcgccg
    19861 tcgctgccat tgaagggcga gggggcgaac ggtacgcgcg cctcaaccgg ggcaagcgcc
    19921 ggcgccgcgg aggccgcgcc ggcgccagac agggcgggca gcagcagggc ggcatgcagt
    19981 gcgcaggcaa tgccggccgg aaacagatgc agcctgcgca acatgtcagc gccccgtcgg
    20041 gttcagatac aggcgcgccc cgtccgattc gcgggcgccg gaccagcgcc ccccaccgga
    20101 ggcacggaat cggcccagca cggtgttgtt ggtatcggtc agcagcagct ggttgcccga
    20161 cagcagccag cggttggccg agaagaagcc gtccgggcag ccggcgggca cgtaggcgct
    20221 gtagccgcca aaccactcgt tgttcttcag ttcgatggtg cagctgctgc cgttttcctg
    20281 gcccagcgtc cagcggccga acagatcgcc gtcgcgtaca tcgggttcat tgcggcggtg
    20341 ctcatgcccc cagtcgtcac tccggtcgtg gaaaccgacc tcgacatcca tgccgctgct
    20401 ttcgctgcgt gactcggtat gtgagctgcc ctgtgtggtg gtctgggtgg tcatcgcacc
    20461 actgttgccg gcggcggaga cgtcagcgct ctgggtctgg gtgctgctgg tctgtgtagt
    20521 ctggtcggtg cgggtggtct gttggccgac gccgaacgag gcgtcctggg ccagggcggg
    20581 cagggccaga cagcacagtg cggacaggca ggtacgggca agcacggcag ccatcgcagg
    20641 atcctcgggc gggagtccgg gcgagtatcc gaccggcggg gcgggagagc gcgtgatggt
    20701 acatcgctgc gttccgagcc accgtggtcg ccgctctcaa tcggccatca cccggccgat
    20761 ggcatcggcc agcagggcac gcaccctggt tggcggtagg tccggatcgc gcactgcgcg
    20821 catcgccagg ccctccacca gcacacgcag cagcagggtg cggccagcga tccgttcctc
    20881 gtcgatggac ttgcccaggc gctggtcgcc gatgcaccgc aggccgtcgc gccccaggct
    20941 actgccgcca acgtgaagcc cgtggccgcc gacgatgatg acccacttcc ccgatttact
    21001 cggcgaggtc gatgtgcagt ggctgggcca cagccaagcg cagtccaggc aggtattgca
    21061 gggcatcgcc gcacaacagg atggcgcggt gctgttccat tgcatggccg gcaaggaccg
    21121 caccggcatc attgccggcc tgctgctgga cctggccggc gtgccgaagg caggtgccgg
    21181 acagtgccgg cacctgccgt acgccatcat ggctgctgcg gtgccacaag aatggacgca
    21241 tccagcaccg ggaatgtctg cggcgcctgg ccggacgacg caaccagacg gatctccagc
    21301 gtcctcgccc cgccagcggc ggcgttgagt gcctgtagtg cccccagttt ctgcggcaac
    21361 ggcaccgcaa acgtggtggg atgactgtgg tccatgccgg gcatgcttgg gccaaagaac
    21421 gatacggtgc ccgcgtagta ggggctgtcg gccgctaccg aggtggtgcc tgcgggcgcg
    21481 ttgatcagca cgtcgaactc gcgggtgttg ttcaacccgc gtggtcgttc cagcgtcacc
    21541 tcggcgatca gctgacgtgg ccctgccgat gccaggtgcg cgcgcaccgc ttcatcgggg
    21601 atggccacgc gcaccgcgcc gtcggaacgc gtgccgcgca ccagccgcac cgcaccggcg
    21661 gcggccggtt gcgcggcggt cttcagcagg tcgttgcggc ccgggtagac gtagtcgtag
    21721 tcgaaggccg tggtggagaa gaacgcactg gccggacgct cgccgacgaa gccaccctgc
    21781 gcgttgacga agaagcggaa cggctcgttc atgaactggc gccgctgctc gacgtccacc
    21841 ggcatgatcg gcttgcctcg ctggtactgc agctgcgtcc acacatccca caggcggtcc
    21901 atgttggcgt ggtgcaggta gaagatcgga tccagcggcg acaggaagtt ggtcatgttg
    21961 ccgtacgggc cgggatcgac cgcgccaaca ccgccgatgc agttgtgcac cttgttgtgc
    22021 gggaagcctt cgagcaccga gaatttcgtg gcgccatccg gttgcaccac gtgtgaggcc
    22081 gtgcgcgaac tggtgaagct gcggctgaca tcggcgttgt agaactccac cggcgacagc
    22141 ccggcatgga tggtgtcggg tgaaaccgcc gagcgcgtct tgtcgtcgaa gccggggttt
    22201 tcccgccaca gatagcgcgc gccgcaggtg atcgcgtagg ccgcgttgcc ggagatgccg
    22261 gtcttctcgg tggcgctgta gccggtcaca tcgttccaga catcgtctgc ggtgagatag
    22321 ccgcgcagct tgagttgtcc gcgctgcccg gcatcgagcg aatcccagta acgctgcagc
    22381 gccggccgca tgaagcgggt gaacaccgcc aggttgcgcg tgtagggggc gtaggcgctg
    22441 tcagtaggcg acagcacccc atcgaacatc gccggcggaa tgcgcggcag ctcggtccag
    22501 tcccagtagg gcatcgcgaa ctgcggatca ccactgagcg tgcggatggt ctgctcgaag
    22561 tagcccacat agccacggtg ccagacgtag aaccaccagt tgccgtgcgg gcagtccatc
    22621 aggtgcacga aggcattgcg gaaccagttg cgcggatcat tcgccggcag tttcagcatg
    22681 gcctcgatgc cgcg
//
