LOCUS       NZ_JALIRS010000009     24235 bp    DNA     linear   CON 12-SEP-2024
DEFINITION  Lysinibacillus sp. BPa_S21 NODE_9_length_189125_cov_178.577, whole
            genome shotgun sequence.
ACCESSION   NZ_JALIRS010000009
VERSION     NZ_JALIRS010000009.1
KEYWORDS    WGS; RefSeq.
SOURCE      Lysinibacillus sp. BPa_S21
  ORGANISM  Lysinibacillus sp. BPa_S21
            Bacteria; Bacillota; Bacilli; Bacillales; Bacillaceae;
            Lysinibacillus.
REFERENCE   1  (bases 1 to 189125)
  AUTHORS   Longdet,I.Y., Kutshik,R.J. and Okenmor,G.A.
  TITLE     Complete Genome Sequence of novel Lysinibacillus spp with high
            Aromatic Hydrocarbon degrading capacity
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 189125)
  AUTHORS   Longdet,I.Y., Kutshik,R.J. and Okenmor,G.A.
  TITLE     Direct Submission
  JOURNAL   Submitted (28-MAR-2022) Department of Biochemistry, University of
            Jos, Bauchi Road, Jos, Plateau State 930003, Nigeria
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: 11-DEC-2020
            Assembly Method :: SPAdes v. DECEMBER-2020; CheckM's leanage_wf v.
            DECEMBER-2020
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 20.0x
            Sequencing Technology             :: Illumina
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_023337795.1-RS_2024_09_12
            Annotation Date                   :: 09/12/2024 05:41:15
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.8
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 4,755
            CDSs (total)                      :: 4,681
            Genes (coding)                    :: 4,604
            CDSs (with protein)               :: 4,604
            Genes (RNA)                       :: 74
            rRNAs                             :: 8, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 8, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 77
            CDSs (without protein)            :: 77
            Pseudo Genes (ambiguous residues) :: 0 of 77
            Pseudo Genes (frameshifted)       :: 30 of 77
            Pseudo Genes (incomplete)         :: 50 of 77
            Pseudo Genes (internal stop)      :: 19 of 77
            Pseudo Genes (multiple problems)  :: 17 of 77
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 18:41:56
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 136107
            Orig. end                         :: 160342
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            JALIRS010000009.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..24235
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="betalactone"
                     /region_number="1"
                     /rules="(HMGL-like and AMP-binding)"
                     /tool="antismash"
     cand_cluster    1..24235
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(HMGL-like and AMP-binding)"
                     /kind="single"
                     /product="betalactone"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..24235
                     /aStool="rule-based-clusters"
                     /category="other"
                     /contig_edge="False"
                     /core_location="[10000:14235](-)"
                     /cutoff="10000"
                     /detection_rule="(HMGL-like and AMP-binding)"
                     /neighbourhood="10000"
                     /product="betalactone"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..14235)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="(HMGL-like and AMP-binding)"
                     /neighbourhood="10000"
                     /product="betalactone"
                     /protocluster_number="1"
     gene            complement(189..1490)
                     /locus_tag="MOK21_RS17395"
                     /old_locus_tag="MOK21_17420"
     CDS             complement(189..1490)
                     /EC_number="2.7.13.3"
                     /GO_function="GO:0000155 - phosphorelay sensor kinase
                     activity [Evidence IEA]"
                     /GO_function="GO:0004673 - protein histidine kinase
                     activity [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_process="GO:0007165 - signal transduction [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008406309.1"
                     /locus_tag="MOK21_RS17395"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MOK21_17420"
                     /product="sensor histidine kinase"
                     /protein_id="WP_249075247.1"
                     /transl_table=11
                     /translation="MDVLTGKMLLMSIIQFSMMLFFCTYILDLYWSKKQLITIIIIIFL
                     PTFLLFPFIGAWSMLYCLSLLAIMMYRETKVVMNILHVCMALILLVIGDNISNILTFRL
                     FNGIGNEQLSIISYFFFYIVFGLIFAFCYKRIVKYLISRWVINSFVSYISVFLGITTVI
                     FMYINIMAIDHDNFYESVQNNLAMFLIYFVLLSISVFVVLYLAFKQYKMKQREQEMKNF
                     ESYVTSIEQINQDMRKFKHDYINILSSLRTFIDDKNYEGLHTYFYDHILEANHHEQLNQ
                     QAMMMLNNLKINSLKGLVTTKILQAQSHHVPFYIEIVEEITDIDVDPILLNRMVGILLD
                     NAIEAARGVENGEVRMAFIHMGEVVLLVVSNTFDKKIAIKVHEIYQEGFSTKGENRGLG
                     LANLRQITNDLHNVNLNTKISSPYFIQEVEFRKE"
     gene            complement(1790..2995)
                     /locus_tag="MOK21_RS17400"
                     /old_locus_tag="MOK21_17425"
     CDS             complement(1790..2995)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008406308.1"
                     /locus_tag="MOK21_RS17400"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MOK21_17425"
                     /product="ABC transporter permease"
                     /protein_id="WP_249075248.1"
                     /transl_table=11
                     /translation="MRNFSIVFNNVFKEAVKTKAYLYMTIGLVGLSLLLFASPFIMKVF
                     TSNSPDETYKIVNQTSLELSEKELTGLAGSWTIVENANIEDLKEDIKTKELTGFFVLED
                     QTNVMQLNIYMPKVNNEVLLTLESYIKQKKVASIVAKQSIDTGVVQELNTPLQSSVQSL
                     YETEPNALFIIYGLITIMFFSISIYGNNVATAIASEKSSRVMEVMITKVAPVPMMYGKI
                     LGIGLASLTQLFIFMGALLLWANVGIFEVPEGSFVQAVMETITWGTAGYILIFCTIGYF
                     IYATLYAIVGSMISRPDDLASASMPIMIILMASLVVEMLFVVDSPEGTMTNITSYIPFT
                     APTSVLIRIVYNTISPIEIAVSLLVMISFIALFAAVAAKIYPKGVLKSDSLTFKQLIQF
                     NR"
     misc_feature    2960..2971
                     /note="TFBS match to CcpA, Catabolite control protein A,
                     confidence: medium, score: 18.34"
                     /tool="antismash"
     gene            complement(2996..3883)
                     /locus_tag="MOK21_RS17405"
                     /old_locus_tag="MOK21_17430"
     CDS             complement(2996..3883)
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008406307.1"
                     /locus_tag="MOK21_RS17405"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MOK21_17430"
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_249075249.1"
                     /transl_table=11
                     /translation="MTFKIENLNKSFGDKKAVNNISIRLEEGQILGMLGRNGAGKTTTI
                     RMMLELIPKDSGQILWKGKPFSKKNLKIGYLPEERGLYAKMNVLDQIIYFGMLEGMDKK
                     EAKREALKWLEKLEISYAAKKRTEQLSKGNQQKVQLITAIIHDPEFIILDEPFSGLDPV
                     NADMLKSVVKELIAQKKTIIFCSHQMDQVESFCNQICILKDGDLIVSDQLSAVKKSYDY
                     RYLELDTTANIKDYLALKQYKFTQENNRYKLRIPRNDKIHQTIREIDEKFDLQGVSLKE
                     PSLHEIFIERTGGA"
     gene            complement(3997..4578)
                     /locus_tag="MOK21_RS17410"
                     /old_locus_tag="MOK21_17435"
     CDS             complement(3997..4578)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014824845.1"
                     /locus_tag="MOK21_RS17410"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MOK21_17435"
                     /product="glycosidase"
                     /protein_id="WP_249075290.1"
                     /transl_table=11
                     /translation="MLIVSTSTLFIEALQIAIRDRRSTWQVDTYQIQTPIFDQTLMKKI
                     KEQCLDIVVVEATNQHFTMTIDSLKKLKCPEIDIMLLVDSRMGEVYHHLKDEERWTSVT
                     KNTSLDEFLILLESFGCNIPDLPDVSLREVDKKILKELAVGHSFEFIQRTQELSAEEID
                     QSLYRINTYFKVPNYIESIVKAFEQKIITN"
     misc_feature    4692..4705
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: medium, score: 22.41"
                     /tool="antismash"
     misc_feature    4693..4706
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: medium, score: 22.54"
                     /tool="antismash"
     gene            complement(4997..5491)
                     /gene="ybaK"
                     /locus_tag="MOK21_RS17415"
                     /old_locus_tag="MOK21_17440"
     CDS             complement(4997..5491)
                     /GO_function="GO:0002161 - aminoacyl-tRNA editing activity
                     [Evidence IEA]"
                     /GO_process="GO:0043039 - tRNA aminoacylation [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="ybaK"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004225525.1"
                     /locus_tag="MOK21_RS17415"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MOK21_17440"
                     /product="Cys-tRNA(Pro) deacylase"
                     /protein_id="WP_249075250.1"
                     /transl_table=11
                     /translation="MAKAKHAKTNAIRLLEQQKIQFEVIEYETGDGQVDGISVAEKIGH
                     PVSRVFKTLVAKASAQKLFVFVIPVADELDLKAAAKVVGEKKIDMLPVKELLGYTGYVR
                     GGCSPVGMKKLYPTVIDASAQEQGNIIVSAGKIGMQIHVQLDDLVAVTKAKLAPITTTQ
                     A"
     gene            complement(5517..6257)
                     /locus_tag="MOK21_RS17420"
                     /old_locus_tag="MOK21_17445"
     CDS             complement(5517..6257)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012292666.1"
                     /locus_tag="MOK21_RS17420"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MOK21_17445"
                     /product="hypothetical protein"
                     /protein_id="WP_249075251.1"
                     /transl_table=11
                     /translation="MKLSSLIEQERMSSQYNRKKILQRKQADDAYRKNSLYFQPKKNPL
                     LLELENLLLGRTDQDLYEQQKEESKEVTPRQQTIMQDLQQTKKNVLAHEQTQKAEAPEY
                     SQIEDLDEEAPFVDDVNANELFQTLEQVRTAALAPAQPSPQDLRVAASANAQLLHMQGQ
                     LNDQELDEREPSFVRETIEVKVPERFLKELKLDPFADTIFGKSYAEAYKARTFKYASEK
                     YATHIQMAKDGYQPGNDPKFSMIA"
     gene            complement(6502..7056)
                     /locus_tag="MOK21_RS17425"
                     /old_locus_tag="MOK21_17450"
     CDS             complement(6502..7056)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008176113.1"
                     /locus_tag="MOK21_RS17425"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MOK21_17450"
                     /product="VanZ family protein"
                     /protein_id="WP_249075252.1"
                     /transl_table=11
                     /translation="MAKNNIQGSAKLPLPYRSLIDTYYLPIKVTGWIFFCIYSVIAFYK
                     LVIDRLVNVVVILFHGEYSLGDLGLFDYSNWRLTTNFVPFDTILRYINYSQYFNFDIII
                     INLLGNLLIFTPMGFLLPLLSKKCRKAWKVICIGFFSSLAVETIQFIFRVGSADIDDLI
                     LNTLGAWLGYLAYKSILIKNR"
     gene            complement(7253..8791)
                     /locus_tag="MOK21_RS17430"
                     /old_locus_tag="MOK21_17455"
     CDS             complement(7253..8791)
                     /EC_number="6.-.-.-"
                     /GO_function="GO:0016874 - ligase activity [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1059: acetyl-CoA carboxylase, carboxyl transferase,"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012292664.1"
                     /locus_tag="MOK21_RS17430"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MOK21_17455"
                     /product="acyl-CoA carboxylase subunit beta"
                     /protein_id="WP_249075253.1"
                     /transl_table=11
                     /translation="MSNVPTENTTKTMKEQILAGGLPKYHDKNAQQGKLFVRERLELLL
                     DDGLQSEDGLYANCLAGDLPADGVVTGIGKIHGRTVCVLANDSTIKAGSWGKRTVEKMI
                     RIQETAEKLNCPLLYLVDSAGARITDQLEMFPGRRGAGRIFYNQVKLSGKIPQICLLFG
                     PSAAGGAYIPAFCDIVVMVEGNASMYLGSPRMAEMVIGEKVDLETMGGAKMHCSVSGCG
                     DVLAKTEQEAIAYARKYLSYFPNNYAERSKVEAPKPPAIFDKSIDELIPKNQNVPFDMY
                     KLIERIIDEDSFCEVKKLFAPELITGLGRINGQSVGIIANQPRVKGGVLFHDSADKAAK
                     FISLCDAFNIPLLFLADVPGFMIGTQVEKAGIIRHGAKMIFAMSEATVPKLTVIVRKAY
                     GAGLYAMAGPAFEPDCCIALSNAQIAVMGPEAAVNAVYANKIAELPKEEQASFIAEKRK
                     EYQEEIDVYRLASELIIDDVIEPNDLRKALESRLELYMSKYLLFSERKHGVNPV"
     gene            complement(9222..10004)
                     /locus_tag="MOK21_RS17435"
                     /old_locus_tag="MOK21_17460"
     CDS             complement(9222..10004)
                     /EC_number="4.2.1.17"
                     /GO_function="GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /NRPS_PKS="Domain: ECH (13-252). E-value: 7.9e-67. Score:
                     217.1. Matches aSDomain:
                     nrpspksdomains_MOK21_RS17435_ECH.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1023: enoyl-CoA hydratase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012292663.1"
                     /locus_tag="MOK21_RS17435"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MOK21_17460"
                     /product="enoyl-CoA hydratase"
                     /protein_id="WP_249075254.1"
                     /transl_table=11
                     /translation="MTQLVRFEVVDHCIGLITLSRPEAANAMSIQLLQELSTTLDNING
                     DPAVRVVLLTGAGEKAFCAGADLKERKGMPDRQVKQIVQLIGATVAKVEALAQPVIAVL
                     NGVAFGGGLELALACDLRLAAAHTKLGLTETSLGIIPGAGGTQRLPRLIGIGKAKELIY
                     TARRLNAEEARNYGIVEYIYEGHEILEKAQQLALEMAKNAPLSLVQAKIAMNQGVEVDL
                     ATGLKIESLAYNALIPTEDRLEGLLAFQEKRTPQYVGK"
     aSDomain        complement(9249..9965)
                     /aSDomain="ECH"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_MOK21_RS17435_ECH.1"
                     /evalue="7.90E-67"
                     /label="MOK21_RS17435_ECH.1"
                     /locus_tag="MOK21_RS17435"
                     /protein_end="252"
                     /protein_start="13"
                     /score="217.1"
                     /tool="antismash"
                     /translation="IGLITLSRPEAANAMSIQLLQELSTTLDNINGDPAVRVVLLTGAG
                     EKAFCAGADLKERKGMPDRQVKQIVQLIGATVAKVEALAQPVIAVLNGVAFGGGLELAL
                     ACDLRLAAAHTKLGLTETSLGIIPGAGGTQRLPRLIGIGKAKELIYTARRLNAEEARNY
                     GIVEYIYEGHEILEKAQQLALEMAKNAPLSLVQAKIAMNQGVEVDLATGLKIESLAYNA
                     LIPTEDRLEGLLAFQEK"
     gene            complement(10001..10918)
                     /locus_tag="MOK21_RS17440"
                     /old_locus_tag="MOK21_17465"
     CDS             complement(10001..10918)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     betalactone: HMGL-like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1271: 2-isopropylmalate synthase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012292662.1"
                     /locus_tag="MOK21_RS17440"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MOK21_17465"
                     /product="hydroxymethylglutaryl-CoA lyase"
                     /protein_id="WP_249075255.1"
                     /sec_met_domain="HMGL-like (E-value: 3.1e-54, bitscore:
                     177.7, seeds: 15, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MQLPKHVTLKEVGPRDGLQNEKTHIATADKVQLVNLLSQTGLNYI
                     EVTSFVHPKWIPQLADAVEVLQAIKRQKDITYAALVPNMRGLERALQAEVDEVSVFMSA
                     SESHNQSNINKSINETFPILQEVVVGAKAAHKNVRGYVSTVIGCPYEGYIQPEKVLRVT
                     EKLFEMGVDEISLGDTIGVGVPTQVENLLEELLKRYPAGNFAMHFHDTRGTALANIVQS
                     LEMGITKFDSALGGLGGCPYAKGASGNVATEDLLYLLDEMGIKTGVERNKVLEAALFIE
                     QKLGKDVASKQMAIVRNERSASQL"
     gene            complement(10934..11146)
                     /locus_tag="MOK21_RS17445"
                     /old_locus_tag="MOK21_17470"
     CDS             complement(10934..11146)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016992214.1"
                     /locus_tag="MOK21_RS17445"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MOK21_17470"
                     /product="acetyl-CoA carboxylase biotin carboxyl carrier
                     protein subunit"
                     /protein_id="WP_249075256.1"
                     /transl_table=11
                     /translation="MATVKASMAGTVWKIVVAEGEKVTAGQDVAILESMKMEIPIAAEE
                     DGVVTKIIASEGDFINVDDDILEIE"
     gene            complement(11227..12585)
                     /locus_tag="MOK21_RS17450"
                     /old_locus_tag="MOK21_17475"
     CDS             complement(11227..12585)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Dala_Dala_lig_C"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ATP-grasp"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) RimK"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1090: acetyl-CoA carboxylase biotin carboxylase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004225534.1"
                     /locus_tag="MOK21_RS17450"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MOK21_17475"
                     /product="acetyl/propionyl/methylcrotonyl-CoA carboxylase
                     subunit alpha"
                     /protein_id="WP_249075257.1"
                     /sec_met_domain="Dala_Dala_lig_C (E-value: 7.5e-14,
                     bitscore: 45.1, seeds: 12, tool: rule-based-clusters)"
                     /sec_met_domain="ATP-grasp (E-value: 4.4e-09, bitscore:
                     29.5, seeds: 20, tool: rule-based-clusters)"
                     /sec_met_domain="RimK (E-value: 7.8e-07, bitscore: 22.3,
                     seeds: 4, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MFKKVLIANRGEIARRVIRTCKRLNVQTVAVYSEADAESLHVKDA
                     DEAFCIGKPPVAQSYLNIDRILEVAKESGADAVHPGYGLLSENAEFAKRCTEAGFVFIG
                     PSADVIASMGSKLEARKTMKAAGVPIVEGVEAPLKDVADAIEIASRLGYPIMLKASAGG
                     GGIGMQLVENAEELAKAFEGNQKRAQSFFGDGTMYMERFIANPHHVEVQIMADHDGNVV
                     PLFERECSIQRRNQKVVEEAPSPFISEETRKRMLDASVKAVQHIGYVNAGTIEYLVDAE
                     QNFYFLEMNTRLQVEHPVTEEITNLDLVEAQLKIAAKQPLAFTRDSIQRKGHAIEVRIY
                     AENPSTFFPSPGTITAFELPTGEGIRHECGVEAGTTVTPFYDPMISKLVVWGETRTIAC
                     ERLIEALQAYKVEGIQTNIPMLLKTVTHEQFLKGYTTTKFVDEYYLPQLAETK"
     gene            complement(12601..14235)
                     /locus_tag="MOK21_RS17455"
                     /old_locus_tag="MOK21_17480"
     CDS             complement(12601..14235)
                     /NRPS_PKS="Domain: AMP-binding (13-445). E-value: 2.2e-101.
                     Score: 331.4. Matches aSDomain:
                     nrpspksdomains_MOK21_RS17455_AMP-binding.1"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     betalactone: AMP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1002: AMP-dependent synthetase and ligase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012292658.1"
                     /locus_tag="MOK21_RS17455"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MOK21_17480"
                     /product="AMP-binding protein"
                     /protein_id="WP_249075258.1"
                     /sec_met_domain="AMP-binding (E-value: 1.2e-109, bitscore:
                     360.0, seeds: 400, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAELVYQTIGQLLDEQSEKYPQREALVYADRDLRMTYEELNRQSR
                     LVARGLMALGIEKSEHIAVWTTNVPEWVQLQFATGKMGAPIVTVNTNYRSSELEYLLKQ
                     SDAKTIILIENYRDHSFMNTLQELCPELNHCEPGNLQSKRLPLLKNVILIGETKYPGVL
                     NWSDVLSAAEQITEEQLDQRQQALHYDDVINIQYTSGTTGFPKGVMLTHYNLVNNAINI
                     AECMRLTYEDRLCIPVPFFHCFGCVIGTLAITTSGGTMVPVQEFSPTEVLQTVEKEKCT
                     ALHGVPTMFISELNLPNFSSFDLSTLRTGVMAGSNCPIEVMKAVIDKMGMKDVTICYGQ
                     TEASPVITQTRADDPLLLKVETVGRALPNLEVKIVIPGTNEEAAPNEQGELCTRGYHVM
                     KGYYKNPEETLLAIDKDNWLHTGDLATMDEAGYVRVTGRLKDMIIRGGENLSPREIEEF
                     LYTHPKIADVQVAGVPDPVYGEEAAAWIILREGEQATEEEIRDYCRDKISRHKIPRHIF
                     FIDDYPMTASGKVQKYRLRESFGATVK"
     aSDomain        complement(12901..14196)
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_MOK21_RS17455_AMP-binding.1"
                     /evalue="2.20E-101"
                     /label="MOK21_RS17455_AMP-binding.1"
                     /locus_tag="MOK21_RS17455"
                     /protein_end="445"
                     /protein_start="13"
                     /score="331.4"
                     /specificity="substrate consensus: X"
                     /tool="antismash"
                     /translation="DEQSEKYPQREALVYADRDLRMTYEELNRQSRLVARGLMALGIEK
                     SEHIAVWTTNVPEWVQLQFATGKMGAPIVTVNTNYRSSELEYLLKQSDAKTIILIENYR
                     DHSFMNTLQELCPELNHCEPGNLQSKRLPLLKNVILIGETKYPGVLNWSDVLSAAEQIT
                     EEQLDQRQQALHYDDVINIQYTSGTTGFPKGVMLTHYNLVNNAINIAECMRLTYEDRLC
                     IPVPFFHCFGCVIGTLAITTSGGTMVPVQEFSPTEVLQTVEKEKCTALHGVPTMFISEL
                     NLPNFSSFDLSTLRTGVMAGSNCPIEVMKAVIDKMGMKDVTICYGQTEASPVITQTRAD
                     DPLLLKVETVGRALPNLEVKIVIPGTNEEAAPNEQGELCTRGYHVMKGYYKNPEETLLA
                     IDKDNWLHTGDLATMDEAGYVRVTGRLKDMIIR"
     CDS_motif       complement(13009..13074)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_MOK21_RS17455_0002"
                     /evalue="1.10E-04"
                     /label="NRPS-A_a6"
                     /locus_tag="MOK21_RS17455"
                     /protein_end="409"
                     /protein_start="387"
                     /score="14.6"
                     /tool="antismash"
                     /translation="QGELCTRGYHVMKGYYKNPEET"
     CDS_motif       complement(13600..13653)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_MOK21_RS17455_0001"
                     /evalue="1.30E-07"
                     /label="NRPS-A_a3"
                     /locus_tag="MOK21_RS17455"
                     /protein_end="212"
                     /protein_start="194"
                     /score="24.0"
                     /tool="antismash"
                     /translation="IQYTSGTTGFPKGVMLTH"
     gene            complement(14268..15410)
                     /locus_tag="MOK21_RS17460"
                     /old_locus_tag="MOK21_17485"
     CDS             complement(14268..15410)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Acyl-CoA_dh_N"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Acyl-CoA_dh_M"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Acyl-CoA_dh_1"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1006: acyl-CoA dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015864021.1"
                     /locus_tag="MOK21_RS17460"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MOK21_17485"
                     /product="acyl-CoA dehydrogenase"
                     /protein_id="WP_249075259.1"
                     /sec_met_domain="Acyl-CoA_dh_N (E-value: 2e-41, bitscore:
                     134.6, seeds: 790, tool: rule-based-clusters)"
                     /sec_met_domain="Acyl-CoA_dh_M (E-value: 3.2e-28, bitscore:
                     91.3, seeds: 43, tool: rule-based-clusters)"
                     /sec_met_domain="Acyl-CoA_dh_1 (E-value: 1.2e-52, bitscore:
                     171.5, seeds: 49, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNFELTKEQVMIRDMVRDFAENEIKPYAREVDETSTMRIESFKKM
                     AELGLLGIPFPEEYGGSGGDTVSYALAVEEIGRACGGTGLSYAAAVSLGASPIYNFGTE
                     EQKQEWLVPLAKGETLGSFGLTEPNAGSDAGGTRTTAVIDGDDYIINGEKCWITNAGYA
                     RQIIVTAVTGKREDGKKIISSIIVPTNTPGVTINCNYDKMGVRGSNTCEIILQNVRVPR
                     ANLLGDEKRGFSQFLNTLDGGRISIAALSVGIAQAAYEKALKYAKEREQFGAPISKLQA
                     IQFKLADMAMEIELARTLVHKAAWLKDQKKPFGKEAAMAKLFASEMGFRTCNQAIQIHG
                     GSGYMKEYDVERHLRDIKLMEIGEGTSEIQRLVISRLIGC"
     gene            complement(15622..16272)
                     /locus_tag="MOK21_RS17465"
                     /old_locus_tag="MOK21_17490"
     CDS             complement(15622..16272)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1057: TetR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003352525.1"
                     /locus_tag="MOK21_RS17465"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MOK21_17490"
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="WP_249075291.1"
                     /transl_table=11
                     /translation="MVKKTLKQRIVDASVVLFQQDGYHNVTVDRIVEYIGASKGGFYHN
                     FKSKDELLYEIHDVFISYVIKQSQEAYDKYNTPITRLCAMLQTLTKVFDMYQAHITVFY
                     EESRSLPEEYSEIIHEKRDQYRDILQKVIEEGQQTKDFRTELPCTIVTMAIVGMINWTY
                     KWFKQSGPLTMEEITEVFTDMVLRAIVTEQAMDEAVQFMVKGEPAVETGFINT"
     gene            complement(16964..18016)
                     /locus_tag="MOK21_RS17470"
                     /old_locus_tag="MOK21_17495"
     CDS             complement(16964..18016)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009334179.1"
                     /locus_tag="MOK21_RS17470"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MOK21_17495"
                     /product="hypothetical protein"
                     /protein_id="WP_249075260.1"
                     /transl_table=11
                     /translation="MKKSWQIGGAFVGLIVGAGFASGQEIMQYFTSFGLYGIAGGIVAT
                     IAFAFLGMSLAQLGANSQTTSHKEVIYQIGGRYVGAILDIVITFFLFGVAVVMFAGSGS
                     TFEQMFGINPMIGSVFMVIMTILTLLLNVKNIINIIALVTPYLMGIVFIILIYSIFTMD
                     LTIAEQNVLAKEQTSAASNWILGALLYVSYNIAAGTAMLIVMGGTVKERKIAGLGGFLG
                     GLMLGILIILINIALFVKMDVVGGTAMPTLELAKQIHPVVGILMSIALLGMMYNTAVGM
                     LYAFTVRFIAPDHQYFKIGIVVIGLIGFVASLVGFTTLVGKVYSTMGYLGFALIIAIII
                     SWLRKIPKAS"
     gene            complement(18074..19180)
                     /gene="menC"
                     /locus_tag="MOK21_RS17475"
                     /old_locus_tag="MOK21_17500"
     CDS             complement(18074..19180)
                     /EC_number="4.2.1.113"
                     /GO_function="GO:0016829 - lyase activity [Evidence IEA]"
                     /GO_process="GO:0009234 - menaquinone biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="menC"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1268: mandelate racemase/muconate lactonizing enzyme"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004225539.1"
                     /locus_tag="MOK21_RS17475"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MOK21_17500"
                     /product="o-succinylbenzoate synthase"
                     /protein_id="WP_249075261.1"
                     /transl_table=11
                     /translation="MKITEITIRHLKMKLKEPFTTSFGTFEDKDFLVLEAKDEAGTIGW
                     GESVAFHSPWYNEETLQTNWHMLEDFLIPLILNKELQHPDEVNELFKPIRKNNMAKSTI
                     EGAIWDIYAQQTNQSLAAALGGKKDNIEVGISIGIQKSIEDLVALVDGFVKEGYKRMKI
                     KIKPGWDVEVMRTLREAFPNVAFMADANSAYSLSDAETLKQLDAFNLTMIEQPLASDDI
                     IDHAALQKLIDTPICLDESIHSLEDARKAVELGSTKIINIKIGRVGGLTEAKKIHDYCE
                     ANNIPVWCGGMLESGIGRAHNVALTTLSNFILPGDTAGSSRYWEKDIIDPEVVVKDGYI
                     EVPQKAGIGYDVNRETIDMFTVAQKTYK"
     gene            complement(19155..20003)
                     /locus_tag="MOK21_RS17480"
                     /old_locus_tag="MOK21_17505"
     CDS             complement(19155..20003)
                     /EC_number="2.3.1.-"
                     /GO_function="GO:0016747 - acyltransferase activity,
                     transferring groups other than amino-acyl groups [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008405429.1"
                     /locus_tag="MOK21_RS17480"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MOK21_17505"
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="WP_308221941.1"
                     /transl_table=11
                     /translation="MRVLIDIREIKTIKQLEQVQQLEYNVWGMPSIPIHQTLTAVKNGG
                     IVVGAYDGDQLVGFSYGFSGFREGKSYLCSHMLGIDENYRSKGIGEQLKYAQQAIAIER
                     GYNLMVWTFDPLETRNGFLNLSKLNGICYTYIENCYGEMQDGLNKGLPSDRFEVCWYIT
                     SDYVSKNVSIDTEGAIPVASCVQNEQGFLCLEITENLKYDKDLYTLPVPKDFQALKLQD
                     PALALDWRFKTRHILQRLFAQGYAAIQLQQQEHYNEYVLVKLEILDLEGANQYENHGNY
                     H"
     gene            complement(20041..21156)
                     /locus_tag="MOK21_RS17485"
                     /old_locus_tag="MOK21_17510"
     CDS             complement(20041..21156)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1244: amidohydrolase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004225542.1"
                     /locus_tag="MOK21_RS17485"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MOK21_17510"
                     /product="M20 peptidase aminoacylase family protein"
                     /protein_id="WP_249075263.1"
                     /transl_table=11
                     /translation="MNQVLQNLQPRLADIFTHLHEHPEISWQEKKTTQYIANILKEAQM
                     EPQLFEDMTGLYVDIGEGIPRVGFRTDIDALWQEVDGKFQANHSCGHDGHMTMAIGTAL
                     VLKDMEHLLPGAVRILFQPAEEKAQGARALVEKGLIDNLEYLFGVHVRPLKELQDGTYA
                     PALYHGAAKLFTGTIIGEEAHGARPELGINVIEVGAAIVEGLQKIWTDPNVSASVKMTQ
                     FNAGGASTNIIPGKATFSIDARAQTNEVMEAITIGVERVKASVEAMYGAKISLNIDAHI
                     VAALVNDEALQHMNSAIVDTVGEKACASPVVTPGGEDFHFYTYERPNLKATMLGLGCGV
                     TPGLHHPKMTFNRERLITGVNIITRAILRAL"
     gene            complement(21162..22028)
                     /locus_tag="MOK21_RS17490"
                     /old_locus_tag="MOK21_17515"
     CDS             complement(21162..22028)
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004225544.1"
                     /locus_tag="MOK21_RS17490"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MOK21_17515"
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="WP_249075292.1"
                     /transl_table=11
                     /translation="MDNQTIQQVIQHKYQELSKSQQKVAIFILKNLQTVGVHSAAYVGD
                     KAGVSETTVIRFCYAIGLSGYAELQREITMHLFNDGKASSLQNYLQSKQALFETPRFYE
                     KTMEKDASSILNVAKNINEEDFDRASFLLHTKKKVYIVGNGSSQLAAQWLHFTLNMLRP
                     NVVLLDFETSEIIRALQEIDEDSVVIILSFHRYFKEPIQFAAEIQEKKCEIIGITDSKI
                     APITQYATITFVNEQQEMSTIDAMPSLISFLNTLIAGMTAQDHDYYENQRIKYDDFQNS
                     FLANRWS"
     misc_feature    22067..22081
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: medium, score: 22.81"
                     /tool="antismash"
     misc_feature    22121..22135
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence:
                     medium, score: 23.58"
                     /tool="antismash"
     misc_feature    complement(22394..22403)
                     /note="TFBS match to AbrC3, Antibiotic production
                     activator, confidence: strong, score: 17.8"
                     /tool="antismash"
ORIGIN
        1 taaatctata tctaaaaaat agcaatcagc tttatcattt tctaaaaatg ctagaacatc
       61 atcaggattt gtagtggcca gcacaatttt catcccattg tcttcaatca tagcgtagtt
      121 ttcgattgtt ttttttgctc tttctaattg agctatatca tcttcgcaaa taataatatc
      181 catcttatct actcctttcg aaactcaact tcttgaataa aataagggga actaattttc
      241 gtgttcaaat tgacgttatg taaatcattt gttatttgac gtaaattagc taagcctaaa
      301 cctcgatttt ctccctttgt tgaaaagcct tcttgataaa tttcatgtac ctttatagct
      361 attttcttat caaatgtgtt actcacaact aataagacaa cctcacccat gtggataaac
      421 gccattcgta cttcgccatt ttcaactcct cgtgcagctt caatcgcatt atctagtaga
      481 atgccgacca tgcgatttaa aagaattgga tctacatcaa tatcagtaat ctcctcaaca
      541 atttcaatat aaaacggtac atgatgtgat tgggcttgta aaattttcgt ggtcactaac
      601 ccttttaaac tgtttatttt taagttattt agcatcatca tcgcttgttg atttagttgt
      661 tcatgatgat tcgcttctaa aatatgatca tagaagtatg tatgtagacc ttcatagttt
      721 ttatcatcaa taaatgtacg cagtgaagat aaaatattaa tgtagtcatg tttaaatttg
      781 cgcatatctt ggttaatttg ttcaattgat gtaacatagg attcgaagtt tttcatttct
      841 tgttcacgtt gcttcatttt atattgttta aatgctaaat ataaaacgac aaatacacta
      901 attgaaagta atacaaaata aattaggaac atcgctaaat tattttgaac actttcatag
      961 aaattgtcat ggtcaattgc catgatattg atgtacataa agatgactgt tgtaatacca
     1021 aggaataccg aaatatacga aacaaagcta ttaattaccc agcgacttat caaatatttc
     1081 acaattcttt tgtaacaaaa agcaaatatt agaccaaata ctatataaaa aaagaaataa
     1141 ctaattattg atagttgctc attccctatc ccattaaaca accgaaaagt cagtatgtta
     1201 gaaatattgt cccctattac taaaagtatc agtgccatac acacatgaag aatgttcata
     1261 acaacttttg tttctcgata catcatgata gctaatagcg ataaacaata taacattgac
     1321 cacgcaccaa taaacgggaa caacaaaaaa gttggcaaaa atataataat tataatagta
     1381 atcaactgtt tttttgacca atataagtct aaaatatatg tacagaaaaa tagcatcata
     1441 gaaaactgaa taatgctcat tagtagcatt tttcctgtta gtacatccat ttatcatact
     1501 cctaacattt tactataaga ccattatatt tcattttaaa aaattctgta cttttaattt
     1561 cttctggaaa ttctatttca tccttccatt ctacaagaat ctccatataa aaatgcatcc
     1621 acaagttcat cccatcgcgt gctaccacgt acaaaaatcg cccataacca gcaattgtgg
     1681 ctacgggctg ttcactattt tgtttaagtt ttgctataaa ctagagcaat tattcttttt
     1741 gccctttgat aacaaaagat cttgacattt tgttcttata atcgcaggac tatctattaa
     1801 attgaattag ttgtttaaat gttaagctat ctgattttaa aacgcctttt ggatagattt
     1861 tcgctgccac tgctgcaaat aaagcaataa aagatatcat tactaatagc gaaacagcaa
     1921 tttcgattgg tgaaatcgta ttatatacaa tacgaatcaa tacactcgtt ggtgccgtaa
     1981 atggaatgta agaagttata ttcgtcatcg ttccttctgg agaatccact acaaagagca
     2041 tctctactac taaacttgcc attaatataa tcataattgg catcgatgca cttgctaaat
     2101 catccgggcg gcttatcatg gatccaacaa ttgcatacaa agttgcatag ataaagtatc
     2161 caatggtaca gaaaataaga atataccctg ctgttcccca tgtaatagtt tccattacag
     2221 cttgtacaaa cgagccttca ggaacttcaa aaatacctac gtttgcccat aataaaaggg
     2281 cacccataaa aataaataat tgtgttaaac tagctaaacc aatgcctaaa attttcccgt
     2341 acatcatagg gactggtgcc acttttgtaa tcatgacttc catgacacgt gaagattttt
     2401 cagatgcaat cgctgttgca acgttgttac cgtatattga aatagaaaag aacataatag
     2461 ttattaaacc gtaaataata aacaacgcat ttggttctgt ttcatataac gattgaacac
     2521 tgctttggag tggtgtattc aattcttgaa cgacacccgt gtcaatcgat tgtttagcaa
     2581 caattgacgc tactttcttt tgtttaatat aagattctaa cgtaagtagc acttcattgt
     2641 ttactttcgg catgtagata ttcaattgca ttacattcgt ttgatcttct aatacaaaga
     2701 atccagttaa ttccttagtt tttatatctt cttttaggtc ttctatattc gcattttcta
     2761 ctattgtcca gcttccggct aaccctgtta actctttttc agatagttct aaagatgttt
     2821 gattgacaat tttataagtc tcatccggac tgttcgaagt aaagactttc atgataaatg
     2881 gtgaggcaaa gagaagtaaa ctcaatccta ctaaaccaat cgtcatatat aaatatgcct
     2941 ttgtttttac agcctctttg aaaacgttat taaatacaat gctaaaattg cgcatttacg
     3001 ccccccctgt tcgttcaata aagatttcat gtaaacttgg ttctttcaat gaaactcctt
     3061 gtaaatcaaa cttttcatca atttcccgaa tcgtttgatg gattttatca tttcgtggaa
     3121 tacgcaattt ataacgatta ttttcttgtg tgaatttata ttgtttcaaa gctaagtaat
     3181 ctttaatgtt agctgttgta tctaattcta aataacgata atcataagat ttttttacag
     3241 ctgataattg atctgacaca attaaatccc catctttcaa aatacaaatt tggttacaaa
     3301 atgattcaac ttgatccatt tgatgactac agaaaataat tgttttcttt tgagcgatta
     3361 attcttttac aacacttttt aacatatcag cattgactgg atctaacccg ctgaaaggtt
     3421 catctaatat gataaactcc ggatcatgta taattgctgt aattaattgt actttttgct
     3481 gatttccttt agataattgt tcagtgcgct tctttgctgc ataagagatt tcaagctttt
     3541 ctaaccattt tagggcctct cttttagctt cttttttatc cattccttct aacataccaa
     3601 aataaataat ttgatctaaa acgttcattt tcgcataaag accacgctct tctggtaaat
     3661 aaccaatttt taagttcttc ttggagaaag gttttccttt ccataaaatt tgtccactat
     3721 ctttcggaat taactctaac atcattcgaa tggtagttgt ttttccggca ccatttcgac
     3781 caagcatgcc taatatttgc ccttcttcta atcgaattga aatattgttt actgcttttt
     3841 tatcaccaaa gcttttattt aaattttcga ttttaaatgt cataaagcat ctctcctaat
     3901 taaccatttt tatgatagca ataacaacga tgccaataat taatccacct aaaagaccta
     3961 aaactttttt catattaatt ttcctccttc gcatgttcaa tttgtaatta ttttctgttc
     4021 aaatgcttta acaatggatt ctatataatt tggtacttta aaataagtat taattcgata
     4081 aagtgactga tctatttctt cagccgatag ctcttgtgta cgttggataa attcaaatga
     4141 gtgacctacc gctaactctt ttagtatctt tttatccacc tcccttaaag agacatctgg
     4201 taaatcaggt atattacatc caaatgattc caacaatatt aaaaattcgt ccagacttgt
     4261 atttttagta acactggtcc acctttcttc atcttttagg tgatggtaga cctcacccat
     4321 ccttgaatcc acaagtaaca tgatgtctat ttctggacat tttaatttct tcaaactatc
     4381 aattgtcatt gtaaaatgtt gattagttgc ttccactacc acaatatcaa ggcattgttc
     4441 tttaattttt ttcatcaagg tttgatcaaa tataggagtt tgaatttgat aagtatctac
     4501 ttgccaagtt gaacgcctat cacgaatagc tatttgtaat gcttcaataa ataaagttga
     4561 cgttgaaaca attaacactt tcaaaacatc cccccctttc tgtctgagaa ttaccttaac
     4621 tacactatac ttttgttttt ctttttattg tttaagtact cttcaaaact aattaattgc
     4681 acattattgt tcttttttaa taaaaaaata cgttcatgca atcatgaacg tatactttct
     4741 tatttacagg aggtcccata tgcgtattta caatgtaaag gaaaagcatt cagactatca
     4801 agattgaacg gatataaagg gcttattcga cttagccgag caatttaccg agctacccga
     4861 acgaactctt tgcttacctg aacagtttgc gaagtaacct aatcgtttct tccacatcgc
     4921 caagcggata accataacca agcaatcttt ttcaactgtc actacttaaa agcccaataa
     4981 aaaactaccc aacatatcat gcttgggtag tggtaattgg tgcgagcttt gcctttgtaa
     5041 cggcaactaa atcatctagt tgtacgtgga tttgcatgcc gattttcccg gcactcacaa
     5101 taatatttcc ttgctcttga gcggacgcat cgatgacagt tgggtaaagt ttcttcatgc
     5161 cgactggaga gcatccgcct cgcacatagc ctgtatagcc aagtaattcc ttgactggaa
     5221 gcatgtcgat tttcttttct cctacaacct ttgcagcagc ttttaaatcg agctcatctg
     5281 ctacaggaat aacaaataca aaaagttttt gtgcacttgc ctttgctact aatgtcttga
     5341 aaacacgaga aactgggtgg ccaatttttt cagcaaccga aattccgtca acttggccgt
     5401 ctccagtctc atattcaatt acttcgaatt gtattttttg ttgctccaat aatcttattg
     5461 catttgtttt cgcatgcttt gctttagcca tgttaaaaaa actcccatct ccagcattag
     5521 gctatcatag agaacttagg gtcatttcct ggttgatagc cgtctttcgc catttgtata
     5581 tgagtcgcat atttttcaga agcgtattta aatgttcgcg ccttataggc ctctgcataa
     5641 ctcttaccga aaattgtatc tgcaaatggg tctaatttca attctttcaa aaaacgttca
     5701 ggtactttaa cttcaatagt ttcacgtaca aaagaaggct ccctttcatc taactcttga
     5761 tcatttagtt gcccctgcat gtgaagtaat tgagcatttg cacttgccgc aacacgtaaa
     5821 tcctgtggtg atggctgtgc gggtgctaac gctgcagtcc tcacctgctc taacgtttgg
     5881 aacagttcat tggcattcac atcatctacg aaaggcgctt cttcatctaa atcctctatc
     5941 tgtgaatatt caggagcttc agctttttgc gtttgctcat gagcgagcac attctttttc
     6001 gtttgttgta aatcctgcat gattgtttgc tgtcgaggcg tgacttcttt agattcctct
     6061 ttttgctgct cgtagagatc ttgatctgta cgccctaaaa gtagattttc gagctcaagc
     6121 aataacggat ttttctttgg ctggaaatac aatgagtttt ttcgatatgc atcatctgct
     6181 tgttttcgct gtaaaatctt tttacgatta tattgtgatg acattctttc ttgttctatt
     6241 aaacttgata gtttcatatg attcacctcg gctttctaag ttaatatgaa agttacgtaa
     6301 taaatatgat agtttctgta tcctaattat cggaattttc ttaatcaaat tcaagagtaa
     6361 atgaatacta agcttctaaa gaaataaata aatttcgata aatcaggcat atagaccttc
     6421 ataagcttgt gatattctat tcatttaata gtttatggtg ttaattcgcc actaaaaaac
     6481 agccctttag taaggactgt tttatctatt tttaatcaat atacttttat aggctaggta
     6541 gccaagccat gctcccaggg tatttaaaat cagatcatcg atatctgccg atccaactct
     6601 aaaaataaac tggatggttt ctaccgctag actagagaaa aagcctatac aaataacttt
     6661 ccaagcttta cgacactttt ttgataatag cggtagtaaa aagcccattg gagtaaatat
     6721 taataagttg ccgagcaaat taataataat gatgtcaaaa ttaaaatact gagagtaatt
     6781 tatataacga agaattgtat caaagggaac aaaattcgtc gttaatcgcc agttgctgta
     6841 atcaaacagc cctaaatcac caagagagta ttcgccatgg aacaaaatca cgactacatt
     6901 cactagacga tcaatcacca gtttataaaa agctatgacg gaatagatgc aaaaaaatat
     6961 ccaacctgtt acctttatcg gtaaataata tgtatctatc agtgaacgat aaggtaacgg
     7021 tagcttggca ctaccctgta tattattttt tgccatgcct ataccaccta cttcccttga
     7081 tcctctcatc attttaatat gcacctcttc accaagcaag gggtaaaaat aagttaggtc
     7141 aaacgttttt attttttccc cttatactat acgtctgtcc aggttcaatt agaaagaaaa
     7201 gctcacaata aaaaagctgc ctccattaac tgagacagca ttttttcgtg ctttatactg
     7261 gatttactcc atgtttacgt tccgagaata atagatattt tgacatatag agctctaaac
     7321 gtgattcgag tgcttttctt aaatcatttg gctcaatgac atcgtcaatg ataagctcgg
     7381 aagctaggcg atagacatcg atttcctctt gatattcctt gcgcttttct gcaataaagc
     7441 ttgcttgctc ctcttttggg agttcagcaa ttttattggc ataaactgca ttgaccgcgg
     7501 cttcaggacc cattacagca atttgcgcat tggatagtgc aatgcaacag tctggctcaa
     7561 aagcaggacc tgccattgca tacagccctg caccatatgc cttacggaca atgaccgtta
     7621 atttagggac agttgcctcg ctcattgcaa aaatcatttt cgctccatgg cgtataatcc
     7681 ctgctttttc aacttgcgta ccaatcataa aacccggtac atctgcgagg aaaagaagcg
     7741 gaatattaaa cgcatcacaa agtgaaatga actttgctgc tttatcagct gaatcgtgga
     7801 ataaaacgcc ccccttgacg cgaggttgat tggcgattat tccgacagat tgcccattaa
     7861 tgcgtcctag tcctgtaatt aattctggag cgaataattt tttcacttca caaaacgaat
     7921 cttcatcaat aatccgttct attagcttat acatatcaaa aggaacgttt tgatttttcg
     7981 gtattagttc atcaatcgat ttatcaaata tagctggtgg ttttggagcc tctaccttac
     8041 tgcgctccgc ataattgttc gggaaatagc ttaaatattt acgagcatag gcaattgctt
     8101 cttgctctgt tttagcaagc acatctccgc aaccggaaac agaacagtgc attttcgctc
     8161 cacccatcgt ttccaaatct accttctcac ctataaccat ttctgccata cgtggagatc
     8221 ctaaatacat cgatgcatta ccctctacca tgactacaat atcgcagaat gcagggatgt
     8281 atgcacctcc tgctgcggaa ggtccaaaca gtaagcatat ttggggaatt ttacctgaaa
     8341 gcttcacctg attatagaaa atgcgtcctg cacctcttcg accagggaac atttccaatt
     8401 ggtcagtaat acgtgcacct gccgaatcga ctagatacaa caatgggcaa tttagctttt
     8461 ctgctgtttc ctgaatacga atcatttttt ctactgtacg tttaccccaa gagccagctt
     8521 taatcgtcga atcgttcgct aatacacaaa cagtgcggcc atggatttta ccgattccag
     8581 ttacaacgcc atctgctggt aagtcacctg ctaagcagtt tgcatacaag ccatcctccg
     8641 attgtaatcc atcatctagt aataattcga gtcgttcacg tacaaatagc tttccttgct
     8701 gtgcattttt atcgtgatat tttggcaggc cccctgctaa aatttgttcc ttcattgttt
     8761 tcgtcgtatt ttctgtcggt acattgctca tcgttaattc ctccttttgc ccaaatcggt
     8821 tacgccttag cataattact ttacccttcg tatttcttct ctcttacatt ccataattat
     8881 aataaattca cttagatttc agatcataaa caaagtgtga ggttgatttc cgttccgacc
     8941 gagcgctttg ccgctgacgc ttcgctttcg cgcagagcag agcttcctgg gggcgtccga
     9001 tgagccgctt cactcgcgtt gctcgctcca gggtctcggg ccaacacgat gttggtcacg
     9061 aaggcgttat cacaggatgt gatggtttta gccttcgttc ccctatcgct gatccccaag
     9121 gagtcgccca gtctctactc caattaactt ttaatcatgg catagattat cttcaccttt
     9181 tgatttagcc atgactttgc cttttggtta aatgcctcct tttatttccc tacatattgc
     9241 ggtgttcgct tttcctggaa agctagtaag ccctctaatc gatcttctgt aggaatcaga
     9301 gcattatatg caagtgattc gatttttaag cccgtagcta aatctacttc aacaccttga
     9361 ttcatggcaa ttttcgcctg tactaaagaa agtggcgcat ttttggccat ttcaagtgca
     9421 agctgctgtg ccttttcaag tatttcatgt ccctcataaa tatactcaac aataccgtag
     9481 tttcttgctt cctcagcgtt taatcgacgt gctgtataaa ttaattcctt cgcttttcca
     9541 atgccaatga gtcgaggaag tcgttgcgta cctcctgccc ctgggatgat gccgagagat
     9601 gtttccgtaa gacctagttt ggtatgggca gcagccagac gtaaatcaca ggctaaagct
     9661 agttcgagtc cgccaccaaa agcaacacca tttagtacgg cgataacagg ttgagcgagt
     9721 gcctctactt ttgccactgt tgccccgatt aattgcacga tctgctttac ttgtcggtct
     9781 ggcatccctt tacgctcttt taaatctgcg cctgcgcaaa aagctttttc ccctgctccc
     9841 gttagtaaga cgactctcac tgccggatcg ccatttatgt tgtcgagtgt cgtgctaagt
     9901 tcttggagta attgtataga cattgcattc gccgcttcag gtcttgaaag tgtaataagc
     9961 ccaatgcaat gatctactac ctcaaaacga acgagttgcg tcataattga ctcgcactcc
    10021 tttcattacg gacaatcgcc atttgtttag aagcaacgtc cttccctagt ttctgttcaa
    10081 taaagagtgc cgcctctagc actttattcc gttccacacc cgttttaata cccatttcat
    10141 ctaacaaata caataaatcc tccgtggcta cattacctga tgctcctttg gcatacggac
    10201 agcctccgag tccaccaagc gcactatcaa acttcgtaat gcccatttct aaagattgaa
    10261 caatattcgc tagtgctgta ccacgtgtat catgaaaatg catcgcgaaa tttcctgcgg
    10321 gatatctttt tagcaattct tctaaaagat tttccacctg tgtcggtaca ccaacaccaa
    10381 tcgtgtcacc aagcgaaatt tcatcgacgc ccatttcgaa taatttctcc gttactcgca
    10441 aaaccttttc tggttgtatg tagccttcat acgggcaccc aatcaccgtt gagacgtagc
    10501 ctcgtacatt tttatgtgct gcctttgccc ctaccacaac ttcctgtaaa atcggaaatg
    10561 tttcattaat cgatttatta atattacttt gattatggct ttcactggca gacataaaca
    10621 cgcttacctc atctacttca gcctgcaatg cacgttctaa gccacgcatg ttcggtacta
    10681 gtgccgcata cgtgatatct ttttggcgtt taatggcttg aagcacctcc actgcatcag
    10741 ccagctgtgg aatccacttc ggatgtacaa aagaagtgac ctcgatataa ttcaatcctg
    10801 tttgactaag taaattcact agctgtactt tatcggcagt tgcaatatgc gttttctcat
    10861 tttgcaaacc gtcacgggga cccacttcct ttaacgttac atgctttggt agctgcataa
    10921 agaaacctcc ttattattcg atttctaaaa tatcatcatc aacgttaatg aaatcccctt
    10981 cgctcgcaat gatttttgta accacgccat cttcttctgc tgcaatagga atctccattt
    11041 tcatcgactc taaaattgct acatcttgtc ctgctgtcac tttctcgccc tctgctacaa
    11101 cgattttcca tactgtccct gccatactcg ctttcactgt tgccattgtc aatccctcca
    11161 agtgtcatta atgttttaga taacgcattc gcactcgtta ttaaagtgcg aatgccttta
    11221 atgtatttat tttgtctctg ctaattgagg tagataatat tcatctacaa atttagtagt
    11281 tgtatagcct tttaaaaatt gttcatgtgt gactgttttc agtagcattg gaatatttgt
    11341 ttgaattcct tctactttat acgcttgaag tgcctcaata agtctttcac aggcaattgt
    11401 tcgtgtttct ccccacacta ccaacttgct aatcatcgga tcgtaaaaag gtgttaccgt
    11461 agtgccagcc tctacgccac attcatggcg aatgccttcg cctgtaggca attcaaaagc
    11521 agtaattgtc cctggagaag ggaaaaaggt cgacggattt tctgcgtaaa tgcgtacttc
    11581 aatcgcatgt ccttttcttt gtatgctatc gcgcgtaaat gccagcggtt gttttgccgc
    11641 gatctttaat tgcgcttcta caagatccag atttgtaatt tcctcagtca cgggatgctc
    11701 cacctgtaaa cgcgtattca tctctaagaa ataaaagttt tgctctgcat ctactaaata
    11761 ctcaatcgtg ccggcattca catagccaat atgttgcact gccttgaccg acgcatctag
    11821 catacgtttt cttgtttctt cagaaatgaa aggagatggt gcttcctcaa ctactttttg
    11881 atttctacgt tgaatcgagc actcacgttc aaatagtggg acgacattgc catcatggtc
    11941 cgccataatt tgcacctcga cgtgatgagg attcgcaata aaacgttcca tatacatcgt
    12001 gccatcacca aagaatgact gtgcacgttt ttgattgccc tcaaaggctt ttgccaattc
    12061 ctctgcattt tcaacgagct gcatgccgat acccccacca ccagcagagg cttttaacat
    12121 aatcggatag cctagtcggg atgcaatttc tatagcgtct gctacatctt tcaaaggtgc
    12181 ttctacacct tcaacaattg gtacacctgc tgccttcatt gttttccgag cttctaattt
    12241 actacccatc gaagcaataa cgtccgcgct tggtccaata aaaacgaagc ccgcctccgt
    12301 acaacgttta gcaaactcag cgttttctga taataagcca tagccgggat gaacagcgtc
    12361 agcaccgctt tccttcgcca cttcaagaat acgatcaata tttaaatagc tttgtgcaac
    12421 aggtggtttt ccgatacaga acgcctcatc cgcgtccttc acatgtaagc tttcagcatc
    12481 tgcctcggaa tacaccgcaa ctgtttgaac atttagtcgt ttgcatgtcc ttataacacg
    12541 tctagcgatc tctccacgat ttgcaattaa aaccttcttg aacataacac tgccccctcc
    12601 ttacttcact gttgcaccga aactctctct taatctatac ttttgaactt ttcctgatgc
    12661 agtcatcgga tagtcatcga taaagaaaat atgtcgtggt attttatgtc tagaaatttt
    12721 atcccgacaa taatctcgaa tctcttcttc tgtagcctgc tctccttctc gcaaaataat
    12781 ccaagctgcc gcttcttctc cataaacggg atcaggaacg cccgcaacct gtacatctgc
    12841 aatttttgga tgtgtataaa ggaattcttc aatttctcta ggcgataaat tttcaccgcc
    12901 ccgaataatc atatctttta aacgacctgt tacacgtaca tagcccgcct catccatcgt
    12961 tgccaaatcc cctgtatgca gccagttatc tttatctatt gcaagaagcg tttcttctgg
    13021 gtttttatag taacctttca tgacatggta gcctctcgta cataactccc cttgttcatt
    13081 cggcgcagct tcttcgtttg taccaggaat gacaatttta acttctagat ttggcaatgc
    13141 gcggcccacg gtttctacct ttaacaatag tgggtcatca gctcttgttt gtgtaataac
    13201 aggtgaggct tctgtttgcc cgtagcagat cgtaacatcc ttcatcccca ttttgtcgat
    13261 aaccgctttc ataacttcga taggacagtt agagccagcc attactccag tacgcaacgt
    13321 tgatagatcg aaagacgaaa aattcggtaa attaagttca ctaatgaaca tcgttggtac
    13381 gccatgtagc gccgtacatt tctctttttc aacagtttgt agcacctcag taggtgagaa
    13441 ttcctgaact ggtaccatcg ttccaccact cgttgtaatg gctaatgtcc caattacaca
    13501 gccaaagcaa tggaagaatg ggacaggaat gcacaagcga tcttcataag ttaaacgcat
    13561 acattctgca atattaatcg cattattgac taagttataa tgcgttaaca taacaccttt
    13621 cggaaaacct gttgttcccg atgtatattg aatattaata acatcatcat aatgaagtgc
    13681 ctgctgtctt tgatctaatt gctcctcagt tatttgctct gcagcagata acacatcaga
    13741 ccaatttagc acgccagggt attttgtctc gccaattaaa ataacatttt tcaataaggg
    13801 tagtcgcttt gattgcaaat tacccggttc acaatgatta agctctggac ataactcttg
    13861 cagtgtattc ataaaagaat ggtctcgata attttcaatt aaaataatcg tttttgcatc
    13921 ggattgcttc aataaatatt ccaactcgct tgaacgataa ttagtgttta cagtgacgat
    13981 tggagcaccc attttacctg tagcaaattg tagctgcacc cattccggga cattggtcgt
    14041 ccatactgca atatgctcac tcttctctat tccaagagcc atcaaccctc tagctaccaa
    14101 acgactttgc cgattgagct cctcgtaggt cattcgtaaa tccctgtctg catacactaa
    14161 tgcttcccgc tgtggatact tctcagattg ttcatctagc aattgaccaa tagtttgata
    14221 cacaagttct gccatgaaaa tcctccttat ttatctactt aagatgatta acagccaatt
    14281 agacgagaaa taacgagacg ttgaatttca gacgttccct caccgatttc cattaactta
    14341 atgtcacgca gatgacgttc tacgtcgtat tctttcatat accctgaacc accatgaatt
    14401 tgaatggctt gattacaagt gcggaagccc atttcagaag caaataattt tgccattgcc
    14461 gcttccttcc cgaatggttt cttttgatct ttaagccatg ccgccttatg tactaacgta
    14521 cgcgcaagct ctatctccat tgccatatcg gctaatttaa attgaattgc ctgaagtttt
    14581 gatatgggtg caccaaattg ttcacgttct tttgcgtatt ttaatgcttt ctcataagcc
    14641 gcctgtgcaa ttcctacaga taatgcagca atggaaatac gccctccatc taacgtattt
    14701 aaaaattggc taaatccgcg tttttcatcc cctaatagat tagcccttgg tacacgaacg
    14761 ttttgcaaaa taatctcaca cgtattggag ccacgtacgc ccattttgtc gtaattgcag
    14821 ttgatcgtta cgccaggagt gttagttggt acaatgatag atgagataat ttttttccca
    14881 tcttcacgtt tacctgtaac tgctgtcaca ataatttgac gtgcataccc agcatttgtg
    14941 atccagcatt tttcaccatt aatgatgtaa tcatcaccat caattacggc tgttgtccgt
    15001 gtccctccag catctgaacc tgcattaggc tctgttaggc caaacgaacc taatgtttcc
    15061 cctttcgcta acggaactag ccattcctgc ttttgctcct ctgtaccaaa attgtaaata
    15121 ggcgaagcac ctaggctaac tgctgctgca tagcttaatc ctgtaccgcc acatgcacga
    15181 ccgatttctt caacagcaag tgcgtaggaa accgtatctc cacctgaccc accgtactct
    15241 tcaggaaacg ggattcctaa taagccaagc tctgccatct ttttaaagct ctctattctc
    15301 atcgtcgatg tctcgtcaac ctcacgagca tacggtttaa tttcattttc agcaaaatca
    15361 cgcaccatgt ctcgaatcat cacttgctct ttcgttagtt caaagttcat ccccagtccc
    15421 cctaatgttt aatttgccat agcggatttc gtttcagatg atagttgtaa aaaatcaatt
    15481 atgcctcggc ataattgcgt ccggaatcgg ctttgggcca acacaatgtt ttttgcgcga
    15541 aagcgtagtg ctaacgcatc ctctctttca acgggggttg agaccggttg aaagaagtta
    15601 ataccgacta gtcggtttgt tttaagtatt aataaaacca gtctctactg ctggctcccc
    15661 cttgaccata aattgtacgg cttcatccat tgcttgttca gtgacaatcg cacgcaatac
    15721 catatccgta aagacttctg taatttcctc cattgttaaa ggacccgatt gcttaaacca
    15781 tttatatgtc cagttaatca tccccacaat agccatcgtt acaatagtac aaggtagttc
    15841 tgtacggaaa tcctttgttt gctggccttc ctctatgact ttttgtaaaa tatcccgata
    15901 ttgatctcgt ttttcatgaa taatttcact atattcttca ggtaatgaac ggctttcctc
    15961 ataaaaaaca gtaatatgtg cttgatacat atcaaatact ttggtcagtg tttgcagcat
    16021 cgcacataaa cgtgtaattg gtgtattgta tttgtcatat gcctcttgtg actgtttaat
    16081 cacatatgaa ataaatacat cgtgaatttc atacaacaat tcatctttcg atttaaaatt
    16141 atgataaaat ccaccctttg atgcaccaat atattcaaca atgcgatcaa cagttacatt
    16201 gtgatagcca tcttgctgaa atagcactac agaagcgtca acaatacgtt gttttaatgt
    16261 tttctttacc ataggcatct atcatccttc ttattactct ttactccatc acctcttata
    16321 attagaaaag gttttaggtc atggccataa tgtgtggttg atttccgttc cggctgggcg
    16381 ctttgttgct gccgcttcgc tttcgcacag aaaacatccg cttcgctgca gggtctcggg
    16441 ccaacagatg ttttttgcgc gaaagcgtag tgctaacgta gcggcagcag caccgatgtt
    16501 ggtcacgaag gcgttatcac aggatgtgat gcttttagcc ttcgttcccc tatcgctgat
    16561 ccccaaggag tcgcccagcc tccactccaa tcaacttatt tacatggtat acgttttaag
    16621 aaaatgtcat cccaaacttc cgatgttgga acaatttatt agaaatcact tgtatggcac
    16681 atcactataa cgtaagtttt aacattatga cgacccttta ttttcctaat tattaaaaaa
    16741 ctatgacacc attaatatag cacccagaaa aattagtgtc tagcaacaaa atagatttta
    16801 tttaaaatta cgagaattta ttttacataa agcagaattt cagaaaacat cccgaatgaa
    16861 caaacataca attattgtat gtttcacgcc ttatttttat gactaaaatt gcaaaaaaat
    16921 tccctagcgc tgtacaaaaa cactagagaa tctcaaaaca tagttatgaa gcttttggta
    16981 tcttacgtag ccacgagatg ataatcgcaa tgattaatgc aaagcctaaa taccccattg
    17041 ttgaatatac ctttccaact aatgtcgtga accctactaa actcgccaca aagcctatta
    17101 aaccaatcac cacgattcct attttaaaat attgatggtc aggcgctata aagcgtactg
    17161 taaatgcata aagcattcct acagctgtat tgtacatcat gcctaataaa gcaatagaca
    17221 ttaagatacc cactacagga tgaatctgtt ttgctagctc taatgttggc atcgccgtcc
    17281 caccaaccac atccatttta acgaacaagg caatattaat aagtatgatt aaaataccga
    17341 gcattaaacc accaagaaaa cctcctaaac cggcaatctt acgctctttt actgttcccc
    17401 ccataacgat taacatcgca gtaccagcag ctatgttata agatacgtag agaagtgcac
    17461 ctagtatcca attagatgcc gcagatgttt gctctttcgc taacacattc tgttctgcaa
    17521 ttgttaagtc cattgtaaat atggagtaaa ttaaaataat aaacacaatt cccattaaat
    17581 atggtgtcac taatgctatt atattaataa tatttttaac gtttaatagc aatgttaaaa
    17641 tcgtcatgat gaccataaaa acactgccaa tcatcgggtt tatcccaaac atttgctcaa
    17701 atgttgaccc cgatccagca aacattacaa ctgctacacc aaataagaag aatgtaatga
    17761 caatatctaa tatagcccca acataacgtc caccaatttg atagataacc tctttatgag
    17821 atgttgtctg tgaatttgca cctaattgcg ctaaactcat ccctaaaaag gcaaatgcaa
    17881 ttgtggccac aattcctccc gctataccgt aaaggccaaa gctcgtaaag tattgcataa
    17941 tctcctgtcc tgaagcaaaa ccagcaccaa cgattaatcc tacaaatgcg ccacctatct
    18001 gccaactttt tttcatagaa cacctgctta tctaatcaat tatattcata ggcttcctaa
    18061 cgaaatatac ttcttattta tatgttttct gtgcaaccgt gaacatatcg atcgtctctc
    18121 tatttacgtc atagccaata cctgcttttt gaggaacctc aatatagccg tccttcacta
    18181 caacttctgg gtcaatgata tccttttccc aataacgact tgagcctgca gtatctccag
    18241 gtaaaataaa attcgataat gtagttaacg ccacattatg tgctcgacca ataccagact
    18301 ccagcatgcc tccacaccaa actggaatgt tatttgcctc acaataatca tgtattttct
    18361 tcgcttctgt taggccacca actctaccaa tcttaatgtt aataatttta gtactgccta
    18421 actcaacagc tttacgtgca tcctccaatg aatggatact ttcatccaag cagattggcg
    18481 tatcgattaa tttttgcaac gctgcgtggt caatgatgtc atctgacgct aatggctgct
    18541 caatcatagt tagattaaaa gcatctagtt gcttaagtgt ttcagcatct gacaggctat
    18601 aagctgagtt cgcatccgcc ataaatgcca cattagggaa cgcttctcgt aatgtacgca
    18661 ttacttctac atcccaacct ggcttgattt tgattttcat gcgtttatag ccttctttaa
    18721 caaaaccatc tactaacgct actaagtcct cgattgattt ttgaataccg atactgatcc
    18781 ctacttcaat attgtccttt ttgccgccaa gtgcagctgc cagtgattga ttcgtctgtt
    18841 gggcataaat atcccagatt gcaccttcaa tagtcgattt cgccatatta tttttgcgaa
    18901 ttggtttaaa taattcattg acctcatccg gatgctgaag ctctttattt aaaataagag
    18961 gaattaaaaa atcttccagc atatgccagt tcgtttgtaa tgtttcctca ttgtaccaag
    19021 gagaatggaa cgccacagat tccccccacc cgattgttcc tgcttcatcc tttgcctcta
    19081 aaactaaaaa atctttatcc tcaaatgtgc caaagctagt tgtaaatggt tcttttaatt
    19141 tcatttttaa atgtctaatg gtaatttccg tgattttcat attggtttgc tccttccaga
    19201 tctaaaattt ctaattttac gaggacatat tcgttgtaat gttcttgctg ctgcaattga
    19261 atagccgcat aaccttgtgc aaataaccgt tgtaaaatat gtcgcgtttt aaagcgccag
    19321 tccaatgcta atgctgggtc ttgcagcttt aatgcttgaa aatcctttgg tacaggtagc
    19381 gtatataaat ctttatcgta ttttaaattt tcagttattt ctaaacatag gaatccctgt
    19441 tcattttgta cacagcttgc aactggtatg gcgccctctg tatctattga aacattttta
    19501 cttacgtaat cagaggttat ataccagcac acctcaaaac ggtctgaagg tagtccttta
    19561 tttaatccat cctgcatttc accgtagcag ttttctatat acgtataaca aataccattt
    19621 aattttgaca gattaagaaa accatttctt gtttccagcg gatcaaacgt ccacaccatt
    19681 aaattgtagc cccgctcaat agcaatagct tgctgggcat attttaattg ttcacctatt
    19741 cctttggagc ggtaattttc gtctatcccc aacatatggg aacataaata gcttttgccc
    19801 tctcgaaatc ctgaaaagcc atagctaaag ccaaccaatt gatcaccatc ataggcacca
    19861 acaacgatac cgccattttt tacagccgtt aaagtttgat gaatgggaat tgaaggcatt
    19921 ccccaaacgt tatattccaa ttgctgaact tgctccagct gtttaattgt ctttatttcc
    19981 cttatgtcaa tcaatactct cacttctttc tattctttat cctctattga tggctagggc
    20041 ctataaagcc cgtaaaatag ctctcgtgat aatgttcact cccgtaataa gccgctctcg
    20101 attaaacgtc attttcggat ggtgtaatcc tggtgttaca ccacaaccta agccaagcat
    20161 tgttgcttta aggttcggac gctcatacgt ataaaaatga aaatcttctc ctccaggagt
    20221 gacgactggt gaagcgcatg ctttttcacc aaccgtatcg acaatagctg aattcatatg
    20281 ttgtaatgcc tcatcattca ctaacgcagc aacaatatga gcatctatat ttaaagaaat
    20341 tttggcacca tacatcgctt ccaccgatgc ctttacacgt tcaacaccaa tcgtgattgc
    20401 ttccattact tcatttgttt gtgctcgtgc atcaatacta aatgttgctt ttcccggaat
    20461 aatgtttgta gaagctcctc ctgcattaaa ttgtgtcatt ttgactgacg cagagacgtt
    20521 ggggtctgtc catatttttt gtaacccttc gacaattgcg gcccctacct caatgacgtt
    20581 aataccgagt tcaggccttg cgccatgtgc ctcttcccca ataatggtcc cagtaaaaag
    20641 ctttgccgca ccatggtaca atgctggggc atacgttccg tcttgtaatt cttttaacgg
    20701 gcgaacatgg acaccgaata agtattctag attatcaata agtcccttct caacaagtgc
    20761 acgagcaccc tgtgcctttt cttcagcagg ctgaaaaaga atacgtactg cgccggggag
    20821 taaatgctcc atgtccttta acaccagtgc cgttccaata gccatcgtca tgtgaccatc
    20881 atgaccgcaa gaatgattag cttgaaattt gccatcaact tcctgccata gtgcatcaat
    20941 atccgtacga aatccgactc tcggtatccc ttccccaata tctacataca gtcccgtcat
    21001 atcctcaaac aactgaggct ccatctgtgc ctccttcaat atattggcga tgtattgcgt
    21061 tgtcttcttt tcttgccagc taatttccgg atgctcatgt agatgtgtaa aaatatcagc
    21121 caatctaggc tgtaagtttt gtaaaacttg attcattgta ttcaactcca tcgatttgct
    21181 aaaaagctat tttggaaatc atcatatttt attcgttgat tttcataata gtcgtgatct
    21241 tgtgcagtca tacctgcaat tagtgtattt aaaaatgaga tcaatgatgg cattgcgtca
    21301 atcgtagaca tttcttgttg ttcattcaca aaagttatcg ttgcatattg cgtgataggt
    21361 gcaattttag aatctgtaat accaataatc tcacattttt tttcttgaat ttcagccgca
    21421 aattgtatcg gttctttaaa ataacggtga aatgataata taatgaccac actatcttca
    21481 tcgatttctt gtaaagctct aatgatttca ctagtttcaa aatctaaaag aactacgtta
    21541 ggacgtagca tatttaatgt aaaatgcagc cattgtgccg ctaattggga ggacccattg
    21601 ccaacaatat agactttctt cttcgtatgc agtaggaacg aagcacgatc aaaatcttcc
    21661 tcgttaatat ttttagcaac atttaaaata ctcgatgcat ccttttccat cgttttttca
    21721 taaaaacgtg gcgtttcaaa tagtgcctgc ttggattgca aataattttg caagctactt
    21781 gcctttccgt cattgaataa atgcatcgtg atctcccgct gcaactcagc ataacccgat
    21841 aatcctatcg cgtagcaaaa gcggattacc gtcgtttcac ttacccccgc tttgtccccg
    21901 acatatgcag cagaatgaac accgacagtc tgcaaatttt tgaggatgaa gatcgctacc
    21961 ttttgctgac tctttgaaag ttcctgatat ttatgttgaa tgacttgttg aattgtttga
    22021 ttgtccatca aagaagtaca tccttctcat tttatttttt gaagtttaaa cttcattttc
    22081 atgttacata cagtagcata cttattttct taattcaata tattttctga aatttctgtt
    22141 tataacgaac aaaaaagcgg gaatgttaat ttatttaaca ctcccgcttt ttttatttat
    22201 aactattcat caaacttcat cccttttaac aaatctgcaa aagcattgtt caaaggttct
    22261 gcttcttttt cttgctgttt catgtatttt tgtacactgc gcttatctac tttgccgccg
    22321 ccctcttttt tacgtcgggc ttcaaatgca gataactttt cacgataacc acatttacat
    22381 acgaaaattt ggccgtcgcc ttcaccgcgt agttctagct ttttcttaca ttgtggacat
    22441 cttgcgtttg tgacacgtga tacgttttta cggtgaccac attcacgatc ttggcaaaca
    22501 agcatcttgc cttttttacc gttgacttca agcattggct tgccacaatc agggcaggat
    22561 tttgttgaga tattgtcatg cttatatttt ttatcactcg ctttaatttc tgtaactatt
    22621 tctttcgtgt gctttttcat ttcgttgatg aacacatctt ttttcagctt accttttgaa
    22681 attaactcaa gcttttgctc ccattcggct gttgtcgctg gagagcgtaa ttcttctggc
    22741 actaaatcaa gcaactgacg acctttagat gtaatgtaaa tttctttgcc gccacgtttt
    22801 tcgattagga atgaattaaa tagcttttcg ataatatctg cacgtgttgc aactgtccct
    22861 aatcctccag ttgatttcaa cgtatctgca agcttcttgt cgttcgtctc catatacttc
    22921 gtaggatttt ccatcgctga tagtaatgtt gcctcggtaa aacgtgcagg tggctttgtt
    22981 tgaccagatg tttgggcaat tagctttgtt tttaatactt gtccttgttc taaacgagga
    23041 agcagttgtt ctttgacatc atccgttgat tcctcatcat caaaacgatt ttgatatact
    23101 tctttccaac cagcattgat aacggttttc cctttagcaa taaatttctc atgcccgatt
    23161 tgtgcttgga cggttaattg ctcatattct tgcgctggga ataacacagc taaaaatcgt
    23221 tttactacta aatcatatat tttacgctct ttatcattga atgcagatac gttcacatag
    23281 ccctcagttg ggatgatcgc gtggtgatca gacactttac tgtcatccac aaatgattta
    23341 ttcgctttaa tcggctttgt taaaatttta ttcgttaatg tacgatattc gccgatgcca
    23401 catgctttta gacgctcagg taatgtgcct ataatatcag atgataaata acgtgaatct
    23461 gttcgcggat atgttagcac tttatgagat tcatatagct tttgcataat atttaatgtt
    23521 tcttttgccg aatagccaaa tagtttattg gcatctcgct gtaattctgt taaatcataa
    23581 agacctgggg caaatgattt tttcggcttg cgatcaattg aagcaatttt tgcatcttga
    23641 ttgcctagtg ctttgacaat aacgtccact ttttctttgt tgaaactacg tgaattacca
    23701 tttgcatctt gccatgtaag ctttaacgaa tctgtttgtg cttcaatacc gtagtacgtt
    23761 tgtggtttaa agtttttaat ttcatcttcg cgtgcagcta tcatcgcaac agttggcgtt
    23821 tgaacacggc cacagtttag ctgtgcatta aatcttgtcg ttaatgcacg tgtcgcgttt
    23881 aatccgatat accaatccgc ttcagaacga gcaaccgcag cagcatatag gttatcgtag
    23941 tttttacctg gttttaaatt agcaaatcct tctttaatgg ctttatctgt aacagatgaa
    24001 atccataaac gtttaatcgg cttatttact ttcgcacgtt caataatcca acgtgctaca
    24061 agctcaccct cacgaccagc atctgttgca ataataattt cgtttacatc gttacgagta
    24121 agctgtgatt ttactgcatt gtattgtttg ctcgtctgtt taatcgttgt taattttaga
    24181 cgctctggta gcatcggtag gtcttctaaa ttccattttt tatatttttc atcgt
//
