LOCUS       NZ_CP086322            21995 bp    DNA     linear   CON 26-NOV-2024
DEFINITION  Streptomyces halobius strain 3_2 chromosome, complete genome.
ACCESSION   NZ_CP086322
VERSION     NZ_CP086322.1
KEYWORDS    RefSeq.
SOURCE      Streptomyces halobius
  ORGANISM  Streptomyces halobius
            Bacteria; Bacillati; Actinomycetota; Actinomycetes;
            Kitasatosporales; Streptomycetaceae; Streptomyces.
REFERENCE   1  (bases 1 to 9239126)
  AUTHORS   Wen,Y., Zhang,W. and Liu,X.G.
  TITLE     Streptomyces nigrumlapis sp.nov.,an antimicrobial producing
            actinobacterium isolated from Black Gobi rocks
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 9239126)
  AUTHORS   Zhang,W., Liu,X.G. and Wen,Y.
  TITLE     Direct Submission
  JOURNAL   Submitted (04-OCT-2021) Northwest Institute of Eco-Environment and
            Resources, CAS, Chinese Academy of Sciences, Donggang West Road 320,
            Lanzhou, Gansu 730000, China
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method :: GS De Novo Assembler v. FEB-2021
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 241.26X
            Sequencing Technology             :: PacBio Sequel
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_023277745.1-RS_2024_11_26
            Annotation Date                   :: 11/26/2024 03:43:17
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.9
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 8,438
            CDSs (total)                      :: 8,346
            Genes (coding)                    :: 7,837
            CDSs (with protein)               :: 7,837
            Genes (RNA)                       :: 92
            rRNAs                             :: 6, 6, 6 (5S, 16S, 23S)
            complete rRNAs                    :: 6, 6, 6 (5S, 16S, 23S)
            tRNAs                             :: 71
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 509
            CDSs (without protein)            :: 509
            Pseudo Genes (ambiguous residues) :: 0 of 509
            Pseudo Genes (frameshifted)       :: 193 of 509
            Pseudo Genes (incomplete)         :: 418 of 509
            Pseudo Genes (internal stop)      :: 17 of 509
            Pseudo Genes (multiple problems)  :: 113 of 509
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 18:33:41
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 6752632
            Orig. end                         :: 6774627
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP086322.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            This genome has a base modification file available.
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..21995
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="blactam"
                     /region_number="29"
                     /rules="(BLS or CAS or tabtoxin)"
                     /tool="antismash"
     cand_cluster    1..21995
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(BLS or CAS or tabtoxin)"
                     /kind="single"
                     /product="blactam"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..21995
                     /aStool="rule-based-clusters"
                     /category="other"
                     /contig_edge="False"
                     /core_location="[10000:11995](-)"
                     /cutoff="20000"
                     /detection_rule="(BLS or CAS or tabtoxin)"
                     /neighbourhood="10000"
                     /product="blactam"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..11995)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(BLS or CAS or tabtoxin)"
                     /neighbourhood="10000"
                     /product="blactam"
                     /protocluster_number="1"
     gene            complement(464..1294)
                     /locus_tag="K9S39_RS30645"
                     /old_locus_tag="K9S39_30785"
     CDS             complement(464..1294)
                     /EC_number="2.3.1.117"
                     /GO_function="GO:0016740 - transferase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008035733.1"
                     /locus_tag="K9S39_RS30645"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="K9S39_30785"
                     /product="2,3,4,5-tetrahydropyridine-2,6-dicarboxylate
                     N-succinyltransferase"
                     /protein_id="WP_248866580.1"
                     /transl_table=11
                     /translation="MSSANIRTPIEDAFKRRSDLTEAELLALTPHIESGLAALDRGELR
                     AASPVDGSWVVDTFVKKLILLSFLTHRNTVVKGGPGQPRTFDKVPLKFEDWDESDFQKS
                     RVRVVPGAVVRHGAHVAPGAVLMPSFVNIGAYVGAGTMIDTWATVGSCAQVGERCHISG
                     GAGLGGVLEPIGDDPVVIEDEVFVGARSEIAEGVRVRRGAVIGMGVFLGRSTPIMDRAT
                     GEVCYGEVPENAVVVAGARADRDRPNISVYSAVIVKYADERTRGKTALNDLVRD"
     gene            complement(1291..2577)
                     /locus_tag="K9S39_RS30650"
                     /old_locus_tag="K9S39_30790"
     CDS             complement(1291..2577)
                     /EC_number="4.1.1.20"
                     /GO_function="GO:0008836 - diaminopimelate decarboxylase
                     activity [Evidence IEA]"
                     /GO_function="GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA]"
                     /GO_process="GO:0009089 - lysine biosynthetic process via
                     diaminopimelate [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Orn_Arg_deC_N"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Orn_DAP_Arg_deC"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1264: diaminopimelate decarboxylase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF014803.5"
                     /locus_tag="K9S39_RS30650"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="K9S39_30790"
                     /product="diaminopimelate decarboxylase"
                     /protein_id="WP_248866581.1"
                     /sec_met_domain="Orn_Arg_deC_N (E-value: 1.3e-32, bitscore:
                     112.1, seeds: 15, tool: rule-based-clusters)"
                     /sec_met_domain="Orn_DAP_Arg_deC (E-value: 2.4e-18,
                     bitscore: 65.1, seeds: 500, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPISDGFARRLLPILKEIVAAYGTPFHIYDARGITHTYRGMVEAY
                     ASVPMQQYFAVKALPNPAVLSLLLAEGSGLDCASPVELELARRVGAVGDDVVFTSNNTS
                     LAEYEQALEAGALITFDDRAFFKRVRTLPETVAFRVSPHGLAAGSALMGDAAHTKFGVP
                     AGELVDVYREARRRGATRFGIHGMISANELDVDRAARAAVDVIELGARVAAAADITLDY
                     VNIGGGLGIPYRPEDKPFDFTAYADAVIQARRRCFPGSGPRILMECGRYVTGPHGILVT
                     RVINRSRKAREIVGLDASMSALMRPGYYGAYHHLSLPFVSGRPEVRVDVVGALCENMDK
                     FAVDRPMPDPAVGDLALIHDTGAHGHSMGFTYNGRLRPAELLLTDDGDIVEIRRAETFD
                     DYLATARWQPQPVLSRGGPAPTQEAREPK"
     gene            complement(2615..3313)
                     /locus_tag="K9S39_RS30655"
                     /old_locus_tag="K9S39_30795"
     CDS             complement(2615..3313)
                     /EC_number="2.1.1.222"
                     /EC_number="2.1.1.64"
                     /GO_function="GO:0008425 -
                     2-polyprenyl-6-methoxy-1,4-benzoquinone methyltransferase
                     activity [Evidence IEA]"
                     /GO_function="GO:0061542 - 3-demethylubiquinol-n
                     3-O-methyltransferase activity [Evidence IEA]"
                     /GO_function="GO:0102208 - 2-polyprenyl-6-hydroxyphenol
                     methylase activity [Evidence IEA]"
                     /GO_process="GO:0006744 - ubiquinone biosynthetic process
                     [Evidence IEA]"
                     /GO_process="GO:0032259 - methylation [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF019846.5"
                     /locus_tag="K9S39_RS30655"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="K9S39_30795"
                     /product="bifunctional 2-polyprenyl-6-hydroxyphenol
                     methylase/3-demethylubiquinol 3-O-methyltransferase UbiG"
                     /protein_id="WP_248866582.1"
                     /transl_table=11
                     /translation="MMIEEKQNLDVVREYYTDLRPAYQADETIYAIWERGGAFNDSVTP
                     STYVPEYRSHILLKLMSLTEKGASVLSLGCGNGFVEGDLAAQERSVRAIDVNEEAVELT
                     RKKGVDAFVADYYALRPEDVAGADAVYADGFLGHLFDAGDEIRPALRKLVSLNLKSGAH
                     LVFSNDAPFDRDAAFEPHQRVQDFWFLSKDYLQESLASFGFSSVESYYFPYLRPISGMR
                     NRTICVVRVP"
     gene            complement(3321..4703)
                     /locus_tag="K9S39_RS30660"
                     /old_locus_tag="K9S39_30800"
     CDS             complement(3321..4703)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="K9S39_RS30660"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="K9S39_30800"
                     /product="hypothetical protein"
                     /protein_id="WP_248866583.1"
                     /transl_table=11
                     /translation="MSEEFAVDRFDYAHNLDKAGTYHKHRSPFWPPSSSYEISCLNFAE
                     HTPDFGPDFLRSLTVLKSAVEAEWQKVKEIGIPARRRFNDPQPIADAMRAVGAHLPGED
                     DRRAVTLRAAAVQDGYNDETLRQLATLEEEFTVVSGQISTWYGKEVKGLPTAFACRRDA
                     SGQALVERALEDRGEVEGYLRGLHADLRLGDVPAFGATHLFHMAGEGNLHPKHIAYFLP
                     EDEGVKYSPFKKTFYFGNTHRALLKNISAPLAARYVDTTTKFNPSDKLFDAIPVLGVLS
                     HELGHCVHRPATDYKGLNAADRWASVVLQEVAADVFGIVILADVWAPKFGLAPADVIAY
                     YLAECLRYVDRGLGHFPDSDGMLLQLSYFVQLGALFLDEENGPRLTGDSEAVLAGLRSL
                     ARVLADTLLADRADAAVSVHRNFGPAADAPLRALVAELRRLPARSVEYTQEHIHTTDGS
                     AA"
     misc_feature    4691..4705
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence: weak,
                     score: 19.14"
                     /tool="antismash"
     gene            complement(4746..6005)
                     /locus_tag="K9S39_RS30665"
                     /old_locus_tag="K9S39_30805"
     CDS             complement(4746..6005)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ATP-grasp_3"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1063: argininosuccinate lyase/adenylosuccinate lyase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF005543.0"
                     /locus_tag="K9S39_RS30665"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="K9S39_30805"
                     /product="ATP-grasp domain-containing protein"
                     /protein_id="WP_248866584.1"
                     /sec_met_domain="ATP-grasp_3 (E-value: 7.1e-06, bitscore:
                     25.1, seeds: 15, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSATKQKVLVVVDGYSSGSQMPAVMAEHGWRCIHVSALSNVPPYY
                     QATFDPDAYIDQFAYEGDVAGLARALESYGPSAVLPGTESGVIVADLLADELGLPGNDP
                     ADSNSHRDKYEMHNRLKKAGLRSMDHFLGRDFEGLLDWARTGNWPVVLKPQASAGTDSV
                     TVCKGEAELETAFRRLYGAINQIGERNDAVLAQRFLTGQEYFVNGISGNGRHVITEIWR
                     TDKIQVPGAGLIYDRSVLLDPTTSETRPIVEYVHGVLDALGIRWGAHHTELMVGNEGPT
                     LIECATRLSGGLNRPAANYTVGISMLDLVANLVVEGEAYAGRFAGMQRNHRYPLWQVQF
                     ISGRTGVVKESFYTELLATLSSRTWLQKAPAPGDRVDVTTDLFSSPGIVFMTHADVAVL
                     QDDHATIREWECENRLFTLK"
     gene            complement(6002..6973)
                     /locus_tag="K9S39_RS30670"
                     /old_locus_tag="K9S39_30810"
     CDS             complement(6002..6973)
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF013088.5"
                     /locus_tag="K9S39_RS30670"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="K9S39_30810"
                     /product="DMT family transporter"
                     /protein_id="WP_248866585.1"
                     /transl_table=11
                     /translation="MTETKTRAESEHAPGVPPKKGSSTLGIAYVSTFLVLANANAVFSG
                     NLLQSMHPFTFLFWSFFVSSVFFGILLVARNGLRALKIDRRSVVPLLILNTTSAFNWIG
                     YFYALHFIEPAIVSAIMGGLGPLCTIVLERFLRKRRFSGWIYVPATGVLLGAGLLAWAS
                     FTGQSGLKDVSVAASVVGLLAAVVGGVSQALNTVATKQLAERAWSATRIMTHRFHLLLL
                     VAAGLALAGPGLSVGGTSQAGLLAIATVLGVIAPLWPLQRGIILSEPFTVAALLSLAPI
                     LTYLFQGFDDRMDWSVASAAGCAVVAVFTVYGTRMIHKGKLE"
     gene            complement(6966..7469)
                     /locus_tag="K9S39_RS30675"
                     /old_locus_tag="K9S39_30815"
     CDS             complement(6966..7469)
                     /EC_number="2.3.-.-"
                     /GO_function="GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA]"
                     /GO_function="GO:0016746 - acyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF012792.5"
                     /locus_tag="K9S39_RS30675"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="K9S39_30815"
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="WP_248866586.1"
                     /transl_table=11
                     /translation="MTGDVTGAGVADRSFTVTPGDPEEPTVARMLRRSEEYAHELYPVE
                     SVHMLHVEELRSPSVRFLVARAKASGAPLACGAVVLYPDRTGEIKRMCVDTGARRQGVG
                     AQVLAALESAARVEGVRTMRLETGVAQPEAIALYRTFGYAERGPFGSYRDDPLSIFMER
                     HLDD"
     gene            complement(7466..9088)
                     /locus_tag="K9S39_RS30680"
                     /old_locus_tag="K9S39_30820"
     CDS             complement(7466..9088)
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF012935.5"
                     /locus_tag="K9S39_RS30680"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="K9S39_30820"
                     /product="GMC family oxidoreductase"
                     /protein_id="WP_248866587.1"
                     /transl_table=11
                     /translation="MSGSVMKTHDYIIVGGGAAGCVLAGRLTEDPSISVLLLESGSERH
                     SPLLSIPAAETVLMGNPKYDWCFETDADPTIAGRSVRIPRGRLLGGSNAINGMIYVRGQ
                     KEDYDDWAALDNPGWSWADVLPYFKSLERAPEIGGENRGRTGLISVGLPRERDELCNAF
                     LESAVKAGYPENPDYNSGDQEGFGYYQVNHAEGRRSSAAGTYLEQARQRPNLTLLTEAH
                     VGGLQFASKRCTGVEFRHKGEVHRAVCRREVIVSAGTVQSPQLLELSGIGSAETLAAVG
                     VPVVHHLPGVGENFRDHFAARLRWRVRQPITFNERSRGLGLVREVAEYVRNRRGLLSLP
                     IALGYGFVRSAEEETRPDIQFHFAPASYGAGSTRRLDTSPGMTVGVYQLRPESKGSIHI
                     RSRVPLTPPAIRPRFLDTELDRTTLVAGMRIARRIVEGPSLAPYREYELTPGRGVRTDE
                     ELLAYARDHGDTSYHPVGTCRMGSDADAVVDQRLRVHGVAGLRVIDASVMPTIVSGNTN
                     AASLMIGEKGAALVLEDHRKGAA"
     gene            complement(9085..9939)
                     /locus_tag="K9S39_RS30685"
                     /old_locus_tag="K9S39_30825"
     CDS             complement(9085..9939)
                     /NRPS_PKS="Domain: TauD (5-273). E-value: 4.1e-62. Score:
                     202.3. Matches aSDomain:
                     nrpspksdomains_K9S39_RS30685_TauD.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) TauD"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1121: dioxygenase, TauD/TfdA"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF014698.5"
                     /locus_tag="K9S39_RS30685"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="K9S39_30825"
                     /product="TauD/TfdA family dioxygenase"
                     /protein_id="WP_248866588.1"
                     /sec_met_domain="TauD (E-value: 5.7e-60, bitscore: 202.3,
                     seeds: 119, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLELVPITDGIGTEVRGIDVAGDISDRDFERVYKAWLDTTILLFR
                     GQTMTPAQHIAFTKRFGEIYMYTRSRFGDGEHPEILILSNLKKDGKPVGSAYSGRVWHS
                     DGHFLTDPPVGSMLHARVVPPVGGDTWYANMYAAYDALPESVKNRVENLKVIISRVQSR
                     PYNYPDRPAPTAEERAEWGDVPHPVVRVHEETGRKALMVGGNVPWRIEGMSEEESLPLV
                     TFLQEFAVQPQFTYCHKWQPGDIVLWDNRSAMHRATYYDDVAHTRLMHRTTISGRRSAS
                     VAA"
     aSDomain        complement(9121..9924)
                     /aSDomain="TauD"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_K9S39_RS30685_TauD.1"
                     /evalue="4.10E-62"
                     /label="K9S39_RS30685_TauD.1"
                     /locus_tag="K9S39_RS30685"
                     /protein_end="273"
                     /protein_start="5"
                     /score="202.3"
                     /tool="antismash"
                     /translation="PITDGIGTEVRGIDVAGDISDRDFERVYKAWLDTTILLFRGQTMT
                     PAQHIAFTKRFGEIYMYTRSRFGDGEHPEILILSNLKKDGKPVGSAYSGRVWHSDGHFL
                     TDPPVGSMLHARVVPPVGGDTWYANMYAAYDALPESVKNRVENLKVIISRVQSRPYNYP
                     DRPAPTAEERAEWGDVPHPVVRVHEETGRKALMVGGNVPWRIEGMSEEESLPLVTFLQE
                     FAVQPQFTYCHKWQPGDIVLWDNRSAMHRATYYDDVAHTRLMHRTT"
     gene            complement(10001..11995)
                     /gene="asnB"
                     /locus_tag="K9S39_RS30690"
                     /old_locus_tag="K9S39_30830"
     CDS             complement(10001..11995)
                     /EC_number="6.3.5.4"
                     /GO_function="GO:0004066 - asparagine synthase
                     (glutamine-hydrolyzing) activity [Evidence IEA]"
                     /GO_process="GO:0006529 - asparagine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="asnB"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     blactam: tabtoxin"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) GATase_7"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Asn_synthase"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1177: asparagine synthase (glutamine-hydrolyzing)"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:TIGR01536.1"
                     /locus_tag="K9S39_RS30690"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="K9S39_30830"
                     /product="asparagine synthase (glutamine-hydrolyzing)"
                     /protein_id="WP_319949595.1"
                     /sec_met_domain="tabtoxin (E-value: 9.5e-234, bitscore:
                     776.2, seeds: 3, tool: rule-based-clusters)"
                     /sec_met_domain="GATase_7 (E-value: 1.5e-28, bitscore:
                     98.1, seeds: 307, tool: rule-based-clusters)"
                     /sec_met_domain="Asn_synthase (E-value: 6e-75, bitscore:
                     252.0, seeds: 78, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAKFSSHQGEAAPGKPLGRLSYLFSLTDSAFSLRSTLLIFGGGGQ
                     RAPGDDLVSGLVGWIDFRHDLSMQESVIHAMTDAMQTRGPDAKGTWISQNAALGHQALI
                     ASEVPAEQPLQERIGAETVAVAVAGEIYNLPELAREIEGAGGVLKTGACPEVLLQAYLL
                     WGDRCVDRVNGAFGFAIWDGRTRKLLLGRDRLGVKPLYYYEYPGGILFASVPKGIMANP
                     RFEARLDLHMLPVALQPRLALPGETPLTGLREVQPGHVLTYTESGLTRRRYWQLTSEPH
                     RDSFDDTARHVRDLLDDIVGRQLISAGPLSSMLSGGVDSTSIAALAVRRLRQDGADRTL
                     DTYCVQFESDLAHFVATELRPDIDAPYAAAAAEYMGSRHHTLTATVQDLLDVIPATRKA
                     RDLPGWGQFDASMYLLFRQIRNNSTVALTGEAADEVFGGYPYFFKKDVFEHGHFPWLGD
                     GPRLSRHLSPELTALIKPEEDELARYSQLMSDVPRLPGEDAENARMREIFYLGLSGPLA
                     VILDRKERMSASLGLDVRVPFCDHRLIEYVWNVPWAMKSRGGVKGLLKAAMADVLPPST
                     ASRKKSAYPHVQNPSYDRTLVREASWIVNDEASPLAGIFDTARMNGLIQQISANAIRSE
                     LPGGSNQAALLIQLVELHNWVDEYGVSLG"
     misc_feature    complement(12188..12205)
                     /note="TFBS match to ArcA, Repressor of carbon oxidation,
                     confidence: weak, score: 16.26"
                     /tool="antismash"
     misc_feature    12196..12209
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 16.38"
                     /tool="antismash"
     misc_feature    12197..12210
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 17.42"
                     /tool="antismash"
     misc_feature    12248..12264
                     /note="TFBS match to NtrC, Nitrogen regulatory protein C,
                     confidence: medium, score: 24.1"
                     /tool="antismash"
     gene            12440..13411
                     /locus_tag="K9S39_RS30695"
                     /old_locus_tag="K9S39_30835"
     CDS             12440..13411
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016575075.1"
                     /locus_tag="K9S39_RS30695"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="K9S39_30835"
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="WP_248866590.1"
                     /transl_table=11
                     /translation="MYGYALSRGIGQGNCVAELTKVLGLHAADIESTIQQLLKMGLLRE
                     LPNQEIAAVPPEEAVSRLVGPLEREVRARRTRIEETRSLLMSFLPVFEVSLAARQQPRP
                     FELLEELSVVRAAIAELAAAAQEEILTAQPGGARQESILEEAAPRDEAALARGVRMRIL
                     YQHTARFSLGTTAYVERAQNGGAQVRTLDDYFPRFLIFDRKTAVLTVLGHPQAALLVRE
                     PNVVAFMIEMYERMWLTGDPYTADHGRRSEISDDLKQAIVRLLVKGMTDASIATRLGMS
                     VRTCRRHIADLMTELGAQSRFQAGHLLAARETNPESRVECDL"
     misc_feature    12441..12454
                     /note="TFBS match to ArgR, Regulator of arginine
                     biosynthesis genes, confidence: medium, score: 18.47"
                     /tool="antismash"
     misc_feature    12551..12553
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            14392..14793
                     /locus_tag="K9S39_RS30700"
                     /old_locus_tag="K9S39_30840"
     CDS             14392..14793
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="K9S39_RS30700"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="K9S39_30840"
                     /product="hypothetical protein"
                     /protein_id="WP_248866591.1"
                     /transl_table=11
                     /translation="MSADTKRNGLVPLGYDTALALEIIPFKGGTKGYLASPEQRRRYLE
                     ALNPAARATTGQPISQHLGPYLLVKGLFFLALMKPTDPARIDKHLKWQYRRHLFMEVLE
                     QYERTGAIDPARFPTLDDFAARHSAPGHP"
     gene            15025..15681
                     /locus_tag="K9S39_RS30705"
                     /old_locus_tag="K9S39_30845"
     CDS             15025..15681
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="K9S39_RS30705"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="K9S39_30845"
                     /product="hypothetical protein"
                     /protein_id="WP_248866592.1"
                     /transl_table=11
                     /translation="MPRELLDGSAVSKDLLAIIDWVVDAGAADVIGVTGSFLVGACNAR
                     SDIDLVCYGPRGYEAAQALFAERALIQPYEGDAQTRLYIRRAKYMTGSSFDALMRQEAR
                     KLQGLTTGAGAHINCEPLRADGDRTLAGVVAQEVGAISVLARVTDHTEGLATPAVYGIA
                     VDTVIGSAARKGVVQAEERLLPSRQRERRVLSGTGRLMNMAAVGPHQHALVRPAR"
     misc_feature    15574..15576
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     misc_feature    complement(15758..15772)
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: weak, score: 18.26"
                     /tool="antismash"
     gene            15812..17083
                     /locus_tag="K9S39_RS30710"
                     /old_locus_tag="K9S39_30850"
     CDS             15812..17083
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1130: transposase"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010063895.1"
                     /locus_tag="K9S39_RS30710"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="K9S39_30850"
                     /product="IS256 family transposase"
                     /protein_id="WP_248869033.1"
                     /transl_table=11
                     /translation="MADDDQAEPSLESAAVEQKLIDQLVEQARSKGLQLTGDGGLLQQL
                     TKTVLESALEGEITDHLGYDKHDPAGKDGGNSRNGTRSKKVLTDIGPVEIDVPRDREGS
                     FEPAIVKKRQRRLTGVDEMVLSLSAKGLTHGEISSHLAEVYGADVSKTTITAITDKVMD
                     GMTEWQNRPLDRVYPVVFIDAINVKIRDGQVANRPIYVALAVTAEGHRDILGLWAGDGG
                     EGAKHWLRVLSELKNRGVEDVLMLVCDGLKGLPDAVGEVWPRTVVQTCVVHLLRASFRY
                     AARQDWGKIAKALKPVYTAPSEDAATTRFLEFAEVWGKKYPAIVRLWESSWAEFTPFLQ
                     FDAEIRRIVCTTNSIESVNARIRKAVRARGHFPTEQAALKCVYMAVMSLDPTGSGRKRW
                     TMRWKGAMNAFDLAFDGRLTAGQL"
     misc_feature    complement(15813..15827)
                     /note="TFBS match to VqsM, Regulator of quorum-sensing
                     signalling systems, confidence: medium, score: 18.37"
                     /tool="antismash"
     gene            17285..17605
                     /locus_tag="K9S39_RS30715"
                     /old_locus_tag="K9S39_30855"
     CDS             17285..17605
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="K9S39_RS30715"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="K9S39_30855"
                     /product="hypothetical protein"
                     /protein_id="WP_248866593.1"
                     /transl_table=11
                     /translation="MAQAAADLGLAPSTLHRWLNDGFIAGEQITPGAPWRIRLTDELRA
                     LFVDTAPAGWLAMLEATLAHGVSRQTLLQRVKRGELRAVHVRTGRRKGLRIEPPAPQNS
                     LF"
     gene            complement(17615..18208)
                     /locus_tag="K9S39_RS30720"
                     /old_locus_tag="K9S39_30860"
     CDS             complement(17615..18208)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF012307.5"
                     /locus_tag="K9S39_RS30720"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="K9S39_30860"
                     /product="reverse transcriptase domain-containing protein"
                     /protein_id="WP_319949596.1"
                     /transl_table=11
                     /translation="MNNDAPPISWPGSMAAERRVLDHQLKLHRWARNEPHRRFKDVFNL
                     VCDRATLLVAWERVSGNRGARTAGVDGLTRYHVEERHGVIPFLEELRSSLKDGSFTALP
                     VKQAVIPKKNGKVRYLGIPTLRDRVAQMALKLVLEPIFEVDFYPSSYGYRPGRRAQDAI
                     AEIHHCTSKPSNYEWDIEGDIKACLEASSHCSFR"
     misc_feature    complement(17990..17992)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            complement(18743..19135)
                     /locus_tag="K9S39_RS30725"
                     /old_locus_tag="K9S39_30865"
     CDS             complement(18743..19135)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF024935.5"
                     /locus_tag="K9S39_RS30725"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="K9S39_30865"
                     /product="transposase"
                     /protein_id="WP_406708043.1"
                     /transl_table=11
                     /translation="MLIVQDDMQPEVWAGELEEVLLRVGHRFGRADLRRRMRDYVRALL
                     GPVGRKNSWQLAEHAGHGTPHGLQNLLNRARWNADEIRDDVQAYTAERLGEPGGVLIID
                     ETGCAPRGAEESSGRRNPPLVIAVTG"
     misc_feature    complement(19228..19240)
                     /note="TFBS match to LuxO, Repressor of luminescence,
                     confidence: weak, score: 19.63"
                     /tool="antismash"
     gene            complement(19287..19736)
                     /locus_tag="K9S39_RS30730"
                     /old_locus_tag="K9S39_30870"
     CDS             complement(19287..19736)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="K9S39_RS30730"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="K9S39_30870"
                     /product="hypothetical protein"
                     /protein_id="WP_248866594.1"
                     /transl_table=11
                     /translation="MRIKWTLYVVLPALMLASGCVITSEESPGATTKPPVQTVTPDEEP
                     TPVVNYDGKTKTVTLGDVKVAATVEVSVINLVVTASNATEKELSYSIDVAISNGETPVF
                     AQTFDIRNIEPGLTKKESSEIDISGYTRTVGEPKVFINDVTTYTE"
     gene            19827..20405
                     /locus_tag="K9S39_RS30735"
                     /old_locus_tag="K9S39_30875"
     CDS             19827..20405
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF020904.5"
                     /locus_tag="K9S39_RS30735"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="K9S39_30875"
                     /product="SMI1/KNR4 family protein"
                     /protein_id="WP_248866595.1"
                     /transl_table=11
                     /translation="MTCELSAWSQITEWIRENAPRSYAQLQEGATSDALAHTRARLGTP
                     LPEELSSMLHMNNGVQVDPNDPDGMRPRRSGEFVSDFYSILSTHLITRVNEHMNAVYNG
                     GEQDGEWKHHWVPFAVESDWLYGLFIDGTTGAVGEWSDGGPIEENVYPSLSAFLEESFQ
                     LIQSRAGIYNEMIVWDIDDLDQEDLDQLT"
     misc_feature    complement(20553..20571)
                     /note="TFBS match to LexA_variant_3, Repressor of DNA
                     damage response, confidence: weak, score: 19.98"
                     /tool="antismash"
     misc_feature    complement(21260..21273)
                     /note="TFBS match to CatR, H2O2-responsive repressor,
                     confidence: medium, score: 19.02"
                     /tool="antismash"
ORIGIN
        1 cgggtgaaat gtctcccggc cggtccagcg tgtagaagac cgggcgcgca cccaccgctt
       61 ccgaggccgc gggataggtc gggtagtagg ggttcggcat gacgacggag gggacgcccg
      121 ccccccagtg ccgcgccgca gccaatgcga tcgccacggc caccgcctgc ttcgtgccgg
      181 gggtcggttc gaccgcggtc ctgccgtcgc ccaggctctc ccgtaccccg aaccggcgct
      241 gaagccagcc ggtgtacgcg gcccgcagct cggcggagcc gccgagctgc gggtaccggg
      301 tccagcccgc tggctccgcc aggagcgccg gctcgatcgc cggtgccgcc agccgggact
      361 ccccgagatg caacaggacg gagtcgagcc cgtcgggcgg ggaaacgcca tcaagcagtt
      421 cccgcagacg ggcgaaggcg ctgcggacag ggctgctcat cgctcagtct cgcaccaggt
      481 cgttcagcgc cgtcttgccg cgtgtccgct cgtccgcgta cttgacgatc accgccgagt
      541 agacggagat gttcggccgg tcgcggtcgg cgcgggcgcc agcgacgacc acggcgttct
      601 ccggcacctc cccgtagcac acctcgccgg tcgcccggtc catgatcggc gtcgagcggc
      661 ccaggaagac gcccatgccg atcaccgcgc cgcgccgtac ccggacgccc tcggcgatct
      721 cgctgcgggc cccgacgaag acctcgtcct cgatcacgac gggatcgtcg ccgatcggct
      781 ctagtacgcc gcccagaccg gcaccgcccg agatatggca gcgctcgccg acctgtgcgc
      841 aggagccgac ggtggcccat gtgtcgatca tggtccccgc gccgacgtag gcgccgatgt
      901 tcacgaacga cggcatgagt acggcacccg gcgcgacatg ggcgccgtgc cggaccaccg
      961 cgcctggtac gacgcggacc cgggacttct ggaagtcgct ctcgtcccag tcctcgaact
     1021 tgagcggaac cttgtcgaag gtccggggct gtcccgggcc gcccttcacc accgtgttgc
     1081 ggtgcgtcag aaacgatagg aggatcagct tcttgacgaa ggtgtccacc acccaggagc
     1141 catccacggg actggccgcc cgcagctcac cgcggtcaag cgccgccaga ccggactcga
     1201 tgtgcggggt gagggcgagg agctccgcct cggtcaggtc ggaacgccgc ttgaaggcgt
     1261 cctcgatcgg tgtcctgatg ttcgcactgc tcacttcggt tctcttgctt cctgtgtggg
     1321 agccggcccg ccgcgcgaca gcacgggctg cggctgccag cgggcggtgg cgaggtagtc
     1381 gtcgaaggtc tctgcccgtc ggatctcgac gatgtcccca tcgtcggtca gcagcagttc
     1441 ggccggccgc agccgcccgt tgtaggtgaa acccatggag tgcccgtggg cgccggtgtc
     1501 gtggatgagg gcgaggtctc cgaccgctgg gtcgggcatg ggccggtcca cggcgaactt
     1561 gtccatgttc tcgcagagcg cgcccaccac gtcgacgcgc acctcgggtc gccctgaaac
     1621 aaagggcagg ctcaggtggt ggtaggcgcc gtagtatccc ggtcgcatga gcgcggacat
     1681 cgacgcgtcc agtccgacga tctcccgtgc cttacgggag cggttgatga cgcgcgtcac
     1741 gaggattcca tggggtcctg tgacatagcg tccgcactcc atcaggatcc ggggcccgct
     1801 tccgggaaag cagcgccgcc gtgcctggat gacggcgtcc gcataggcgg tgaagtcgaa
     1861 cggcttgtcc tcgggccggt acgggatgcc caggccgccg ccgatgttga catagtcgag
     1921 tgtgatgtct gccgcggcgg ccacccgggc gcccagttcg atcacgtcga ccgcggcccg
     1981 cgcggcccgg tcgacgtcca actcgttggc gctgatcatg ccgtgaatgc cgaagcgggt
     2041 tgctcctcta cgacgggcct cccggtagac gtcgacgagt tccccggcgg gaacgccgaa
     2101 cttcgtgtgg gcggcgtccc ccatgagggc cgaaccggcc gccaggccgt ggggtgagac
     2161 ccggaaggcc acggtctcag gcagggtgcg cactcttttg aagaaggccc ggtcatcgaa
     2221 tgtgatcagg gccccggcct cgagtgcctg ctcgtactcc gcaagcgagg tgttgttaga
     2281 cgtgaacacc acgtcgtccc cgaccgcgcc gacccgacgg gccagttcga gctcgacagg
     2341 cgaagcgcag tcgaggccgc ttccctcggc caggagaagg gacagtacgg cagggttcgg
     2401 cagggccttg acggcgaagt actgctgcat cggtacgctc gcgtaggctt ccaccatgcc
     2461 tcggtaggtg tgggtgatgc cacgagcgtc gtagatgtgg aacggagtgc cgtacgcggc
     2521 gacaatctcc ttgagtatcg gcagaagcct tcgggcgaac ccatccgaaa tgggcaatgt
     2581 tccccctcct tccttccgga cctggacgcg tcgtctacgg gacgcgcacg acgcagatgg
     2641 tgcgattccg cattccgctg atggggcgca ggtacgggaa gtaatagctc tccacggagg
     2701 agaacccaaa ggacgccagg ctctcctgga ggtagtcctt ggacaggaac cagaagtcct
     2761 ggacacgttg gtgcggctcg aaggcagcat cacggtcgaa cggggcgtcg ttggagaaca
     2821 ccaggtgggc gcccgacttg aggttgaggc tcaccaactt gcgcagcgcg ggccgaatct
     2881 cgtcccccgc gtcgaagagg tgaccgagga acccgtccgc gtagaccgcg tcggccccgg
     2941 cgacgtcctc cggccgcagc gcgtagtagt cggcgacgaa ggcgtcgacg cccttcttcc
     3001 gggtgagttc gaccgcttcc tcgttgacgt cgatcgcacg caccgagcgc tcctgagcgg
     3061 ccaggtcgcc ctcgacgaag ccgttgccgc acccgagaga gaggacgctc gcgcccttct
     3121 cggtcagcga catcagcttg agcagtatgt gagaccggta ctcggggaca tacgtggagg
     3181 gggtgacgga gtcgttgaag gccccgccgc gctcccagat ggcgtagatg gtctcgtcgg
     3241 cctggtaggc aggtcgcagg tcggtgtagt actcgcggac cacatcgaga ttctgttttt
     3301 cctcgatcat catcgtcctc ctaggcggcg gagccgtcgg tcgtgtggat gtgctcctgc
     3361 gtgtattcga ccgacctggc gggcagtcgg cgcagctcgg cgacgagcgc ccgcagcggg
     3421 gcgtctgcgg ctggaccgaa gttccggtgc actgagaccg ccgcgtcggc ccggtcggcg
     3481 agcagcgtgt cggctaggac ccgggccagc gagcgcaggc cggccaggac ggcctcggaa
     3541 tcaccggtca ggcggggccc gttctcctcg tcgaggaaga gggcgcccaa ctggacgaag
     3601 tacgacagct gcagcagcat gccgtcgctg tcggggaagt ggccgaggcc acggtcgacg
     3661 tagcgcaggc actccgccag gtagtaggcg atgacgtcgg ccggcgccag accgaacttc
     3721 ggtgcccata catcggcgag gatcacgatg ccgaagacat cggcggcgac ctcctggagg
     3781 acgacggagg cccagcggtc ggccgcgttc aggcccttgt agtcggtggc cggacggtgc
     3841 acgcagtggc ccagctcgtg gctgagcacg cccagcaccg ggatggcgtc gaagagtttg
     3901 tcgctcgggt tgaacttcgt agtggtgtcc acgtaacggg ccgccaacgg cgccgagatg
     3961 ttcttcagca gcgcacggtg cgtgttgccg aagtagaacg tcttcttgaa gggcgagtac
     4021 ttgacgcctt cgtcctcggg taggaagtag gcgatgtgct tggggtgcag gttcccctcg
     4081 cccgccatgt ggaagaggtg ggtcgcgccg aacgccggca cgtcgccgag gcggagatcg
     4141 gcatggaggc cccgcaggta cccctcaacc tcgccccggt cctccagggc ccgctccacg
     4201 agggcctggc cgctcgcgtc tcgacggcag gcgaatgccg tcgggaggcc cttgacctcc
     4261 ttgccgtacc aggtggaaat ctggccggat acgacggtga actcctcctc aagagtggcg
     4321 agttgcctga gagtctcgtc gttgtagccg tcctggacgg cggcggcgcg gagggtgacg
     4381 gctcggcggt cgtcttcacc cggcaggtgt gcgccgacgg cgcgcatggc gtccgcgatg
     4441 ggctgcgggt cgttgaagcg gcggcgagcg ggaataccga tctccttgac cttctgccac
     4501 tccgcctcca ccgcggactt cagcacggtg aggctgcgca ggaagtcagg tccgaaatcc
     4561 ggggtgtgct ccgcgaaatt caggcacgat atctcgtagc tggaggaggg cggccagaag
     4621 gggctgcggt gcttgtgata ggtgcccgcc ttgtcgaggt tgtgcgcgta atcgaagcga
     4681 tcgactgcga attcttcaga cattgggttt cccgttctgg ggaagcatgt tccggtcacc
     4741 gtcggctact tgagcgtgaa gagtctgttc tcgcattccc attcacgaat ggtcgcgtgg
     4801 tcgtcctgga ggactgcgac gtcggcatga gtcatgaaga cgatgccggg actggagaag
     4861 agatcggtgg tgacgtccac gcggtcgccg ggggcggggg ccttctggag ccaggtccgg
     4921 ctgctgagcg tcgcgagcag ttcggtgtag aaggactcct tcaccacgcc cgtccggccg
     4981 gagatgaact ggacctgcca cagcgggtac cggtggttcc gctgcattcc ggcgaatcgc
     5041 ccggcgtacg cctcgccctc gacgaccagg ttcgcgacca ggtcgagcat gctgatgccg
     5101 accgtgtagt tcgcggcggg gcggttgagc ccgccggaca ggcgcgtggc gcattcgatg
     5161 agcgtcgggc cctcgttgcc gaccatcagt tccgtgtggt gggcacccca acggatgccg
     5221 agcgcgtcga gcactccgtg gacgtactcg acgatcggcc gcgtctcgga cgtggtgggg
     5281 tccagcagga cactgcggtc gtagatcagt cccgcgcccg gcacctggat cttgtccgtg
     5341 cgccagatct ccgtgatgac atgtctaccg ttcccgctga ttccgttgac gaagtactcc
     5401 tgcccagtga gaaagcgctg ggcgagcacc gcatcgttgc gctcacctat ctgattgatg
     5461 gctccgtaga gacgacggaa cgccgtttcc agttcggcct cacccttgca gacggtcacg
     5521 gaatccgtac ccgcgctcgc ctggggcttg agaaccaccg gccagttccc ggtccgtgcc
     5581 cagtcgagga gcccctcgaa gtcccggccc aggaagtggt ccatgctgcg cagtcccgcc
     5641 ttcttgaggc ggttgtgcat ttcgtacttg tcccggtggg aattgctgtc cgccgggtcg
     5701 ttccctggaa gtccgagctc gtcggccagc aggtcggcga cgatgacccc gctctccgtg
     5761 ccgggcagga cagccgaagg gccgtaactt tccagcgccc gagcgagacc ggcgacgtcg
     5821 ccctcgtagg cgaactgatc gatgtacgca tccgggtcga aggtggcctg atagtaagga
     5881 ggaacattgc tcagggcgga tacgtggata cacctccagc cgtgctcggc catgacggcc
     5941 ggcatctgcg atccggaaga atatccgtcg accactacca gtaccttctg ctttgtcgcg
     6001 ctcactccag cttccccttg tggatcattc gcgtgccgta gacggtgaat accgcgacca
     6061 cggcacatcc ggcggcggat gcgacggacc agtccatccg gtcgtcgaat ccctggaaca
     6121 gataggtcag gatcggggcc agcgaaagta gcgcggccac cgtgaacggc tcggaaagga
     6181 tgattccgcg ctggagcggc cagaggggcg cgatgactcc aagtacggtg gcaatcgcga
     6241 gcagaccggc ctgcgaggta cccccgaccg aaagaccggg cccggccagg gcgagccccg
     6301 ccgccacgag gagcagcaga tggaaacggt gcgtcatgat tcgcgtggcg ctccacgccc
     6361 gctccgccag ttgcttcgtg gccacggtgt tcagcgcctg ggaaacaccg ccgaccaccg
     6421 cggccagcag tccgaccacg gaggccgcga cgctgacgtc cttgagccct gactgcccgg
     6481 tgaacgaggc ccaggccagc agcccggcgc ccagcaggac gccggtggcc ggcacataaa
     6541 tccagccgga gaaccgccgc ttgcgcagaa aacgctccaa aacgatagtg cacagcggac
     6601 ccagtccacc cataattgcg ctcacgatgg ccggctcgat gaaatgcagt gcataaaagt
     6661 agccgatcca gttgaaggcg ctggtcgtat tcaggatcag cagcggtacg accgaccgtc
     6721 tgtcgatttt cagtgcgcgc agcccgttcc gtgccaccag cagaattccg aagaacacgc
     6781 tgctgacgaa gaagctccag aataggaacg tgaacggatg catgctctgc agcagattcc
     6841 cggagaacac cgcattggcg ttcgctagga cgaggaaggt cgagacatag gcgattccca
     6901 gtgtcgacga gccctttttg ggcggaaccc cgggagcgtg ttccgactcc gcgcgggtct
     6961 tcgtctcagt catccaggtg cctctccatg aagatgctga gagggtcgtc acggtaggag
     7021 ccgaagggtc cgcgctcggc gtacccgaag gtgcggtaca gggcgatggc ctcgggctgg
     7081 gcgacgcccg tctccagtcg catggtgcgg acgccctcga cgcgagctgc cgactcaagg
     7141 gcggcgagca cttgggcgcc tacgccctgc cgacgggcac cagtgtcgac acacatccgc
     7201 ttgatctcgc cggtacggtc cggatacagc accacggccc cgcacgcgag cggggcgccc
     7261 gacgccttgg cacgggccac caggaaccgt acggacggcg agcgcagttc ctcgacgtgc
     7321 agcatgtgga cgctctccac cgggtacagc tcgtgcgcgt actcctccga ccggcgcagc
     7381 atccgggcca ctgtcggctc ttccgggtca ccgggggtga cagtgaacga ccggtcggct
     7441 acccctgctc cggtgacgtc ccccgtcatg cggccccctt ccggtggtcc tccagcacca
     7501 aggccgcgcc cttctcgccg atcatgaggc tggcggcgtt ggtgttgccc gagacgatgg
     7561 tgggcatgac ggacgcgtcg atcacgcgca gtccagccac gccgtgcaca cgcagccgct
     7621 ggtcaaccac ggcgtcggcg tcgctgccca tacggcaggt gccgacgggg tggtacgagg
     7681 tgtcgccgtg gtcgcgcgcg tacgccagca gttcctcgtc cgtccggacc ccgcggcccg
     7741 gcgtcagctc gtactcgcgg tagggggcga gactgggccc ctcgacgatt cgccgggcga
     7801 tccgcatgcc ggccacgagc gtggtccggt cgagttccgt gtcgaggaag cgcggccgga
     7861 tcgcgggcgg cgtcagcggg acgcgggagc ggatgtggat ggaacccttc gactcgggac
     7921 gcagctggta cacgcccacg gtcatgccgg gggaggtgtc gagacgccgg gtcgatccgg
     7981 cgccgtagct ggccggggcg aagtggaact ggatatcggg gcgggtctcc tcctccgcgg
     8041 acctgacgaa gccgtaaccc agggcgatgg gcaggctcag cagcccgcgc cggttgcgta
     8101 cgtactcggc gacctcccgg accaggccga gtccacggga ccgctcgttg aaggtgatcg
     8161 gctgccgcac ccgccagcgc agccgggcgg cgaagtggtc ccggaagttc tcgccgacac
     8221 cggggaggtg gtggacgacg ggcactccca cggcggcgag ggtctccgcc gaaccgatac
     8281 cggagagttc cagcagctgc ggcgactgca ccgtacccgc gctgacgatc acttcacggc
     8341 ggcagacggc ccgatggacc tcgcccttat gccggaactc cacaccggtg cagcgcttgc
     8401 tggcgaactg gagtccgccg acgtgcgcct ccgtcaggag ggtcaggttc gggcgctgcc
     8461 gggcctgctc cagataggtg ccggccgcgg aggagcggcg cccctccgcg tggttgacct
     8521 ggtagtagcc gaagccttcc tggtcaccgg agttgtagtc cgggttctcc ggatagccgg
     8581 ccttgacggc cgattcgagg aaggcgttac acagttcgtc tcgttcacgc gggagaccga
     8641 ccgagatcag gccggtccgg ccgcggttct cgccgccgat ctcgggcgcg cgctcaaggc
     8701 tcttgaagta gggaagcaca tccgcccagg accagccggg gttgtcgagc gccgcccagt
     8761 cgtcgtagtc ctccttctgg ccgcggacgt agatcatgcc gttgatggcg ttcgacccgc
     8821 cgaggagccg gcctcgggga atccgcacgc tgcgtcctgc gatggtcgga tcggcgtccg
     8881 tctcgaaaca ccagtcatac ttcggattgc ccatcagcac cgtctcggcc gccgggatgg
     8941 agaggagcgg gctgtgccgc tcgctgcccg actcaagcag cagcacactg atcgacgggt
     9001 cctcggtgag ccgccctgct agcacacagc ccgcggcgcc cccaccgacg atgatgtagt
     9061 cgtgcgtctt catgaccgac ccgctcacgc cgcgacggag gccgaccgac ggcccgagat
     9121 ggtggtgcgg tgcatcaggc gtgtgtgcgc gacatcgtcg tagtaggtcg cccggtgcat
     9181 cgcgctgcgg ttgtcccaca ggacgatgtc gcccggctgc cacttgtggc agtaggtgaa
     9241 ctggggctgg acagcgaact cctggaggaa tgtgaccagg gggaggctct cctcctcgga
     9301 catcccctcg atccgccacg gtacgttgcc gccgaccatg agggccttgc ggccagtctc
     9361 ctcgtggaca cggacgacgg ggtggggcac gtcgccccac tcggcacgtt cctcggcggt
     9421 gggcgccggg cggtcggggt agttgtacgg acgggactgg acccggctga tgatgacctt
     9481 gaggttctcg acgcggttct tgacggactc gggcagggcg tcgtaggcgg cgtacatgtt
     9541 ggcgtaccag gtgtcgcctc cgaccggcgg caccacacgg gcgtgcagca tcgagccgac
     9601 cggcggatcg gtgaggaagt ggccgtcgct gtgccagaca cggccgctgt acgccgagcc
     9661 caccggcttc ccgtccttct tgagattcga caggatcagg atctcggggt gctcgccgtc
     9721 gccgaaccgc gagcgggtgt acatgtatat ctcgccaaac cgcttggtga acgcgatgtg
     9781 ctgcgcgggg gtcatggtct ggccccggaa cagaagaatc gtcgtgtcga gccatgcctt
     9841 gtagacacgc tcgaaatcgc ggtcggagat gtcgcccgcg acgtcgattc cgcgtacttc
     9901 agtgccgata ccgtcggtga tgggtacgag ctcaagcatg aaggatctcc cttgggtttc
     9961 ctacggggga tgaggtgctc acgaggtgct ccggcgagcg tcagccgagc gacaccccgt
    10021 attcgtcgac ccagttgtgc agctctacca gttggatcag cagtgcggcc tggttcgatc
    10081 cgcccggcag ctccgaacgg atcgcgttgg cgctgatctg ctggatgagc ccgttcatcc
    10141 tcgcggtatc gaatattccg gccaggggag atgcctcgtc gttgacgatc cacgacgcct
    10201 cgcggacgag tgtccggtcg taggacggat tctggacgtg cgggtaggcg ctcttcttcc
    10261 gactggcggt gctcggcgga agaacatccg ccatggccgc cttgagcagg cccttcacgc
    10321 cgccccgcga cttcatggcc cacggtacgt tccacacgta ctcgatcagc cggtggtcgc
    10381 agaacggcac ccgtacatcc aggccgagcg aggcgctcat gcgctccttg cggtcgagga
    10441 tgacagcgag cggcccggag aggccgaggt agaagatctc ccgcatccgc gcgttctcgg
    10501 cgtcctcgcc gggcagccgg gggacgtccg acatcagctg ggagtaccgc gcgagttcgt
    10561 cctcctccgg cttgatcagt gcggtcagtt ccggggagag atggcgcgag agcctggggc
    10621 cgtctccgag ccagggaaag tggccgtgct cgaacacgtc ctttttgaag aagtacgggt
    10681 agccgccgaa gacttcgtcc gcggcctcac cggtcagcgc gacggtggag ttgttgcgga
    10741 tctgacggaa gagcaggtac atcgatgcgt cgaactggcc ccatcccggg aggtcacggg
    10801 ccttgcgggt ggctgggata acgtccagca ggtcctgcac cgtggcggtg agggtgtggt
    10861 ggcggctgcc catgtactcg gcggcggctg ccgcgtaggg agcatcgatg tccgggcgca
    10921 gctcggtcgc cacgaagtgc gccaggtcgc tctcgaactg cacgcagtag gtgtcgaggg
    10981 tccggtcggc gccgtcctgg cgtagtcggc ggacggcgag cgccgctatc gacgtcgagt
    11041 cgactccgcc tgagagcatg ctgctgagtg gcccggccga gatcagttgg cggccgacga
    11101 tgtcgtccag cagatcccgg acatggcgtg cggtgtcgtc gaaggagtcg cggtggggtt
    11161 cgctggtcag ctgccagtag cggcgtcgcg tcagaccgga ctccgtgtat gtcagcacat
    11221 gtccgggttg tacctcgcgg agcccggtca gtggtgtctc gccgggcagg gccagtcgag
    11281 gctggagggc gaccgggagc atatggaggt cgagccgcgc ttcgaagcgc ggattggcca
    11341 tgatgccctt cggaacggat gcgaagagaa tgccgccagg gtattcgtag tagtagagcg
    11401 gcttgacacc cagacggtcg cggccgagca ggagctttcg agttcgtccg tcccagatcg
    11461 cgaatccgaa ggcgccgttg acacggtcca cgcatcggtc accccagagc aggtatgcct
    11521 ggaggagaac ttccgggcag gcgccggtct tgaggacccc accggcgcct tcgatttcac
    11581 gggcgagttc cggcagattg tagatttctc ccgcgacggc gacggccacc gtctccgctc
    11641 cgattcgctc ctgaaggggc tgctcggccg ggacttcgga ggcgataagg gcttggtggc
    11701 cgagtgcggc attctgggaa atccaggttc ccttggcgtc agggccacgg gtctgcatcg
    11761 cgtccgtcat cgcatggatg acactttcct gcatgctcag atcatgacga aaatcaatcc
    11821 agcccaccaa gccactcact agatcatctc ctggggcacg ctgtccacct ccgccgaaaa
    11881 tgagcagggt ggagcgcaac gagaaagcgg aatcggtaag agagaaaagg taggaaagac
    11941 gcccgagcgg ctttcccggg gcagcctccc cctgatgact actgaacttc gccacgtgat
    12001 gtcgctggca cggcggcccc ggcctgcggc aatcagctac cgaggtgcga catcacgcga
    12061 agatcatcag taaccccagc cggtgtcgtt gatgtcggcg gcggtcgccc ggccccagcc
    12121 cctgtcattc gaacccgttc cggccagtgg ggctgtgagg ccagccacca cggccagcgc
    12181 ccctcgaaca acaagaatct tacaaaaaag cctcataacg ccccctggct gtttcgggac
    12241 ttgacgatgc ccactgccgg tgcgccgttg caccccccag ggcctgacac tgaacaccat
    12301 ggcatgtcgc acatgtttac ggactgacag gactgatcat gatgctgcat ggcaccttgc
    12361 tgacaggctc gcgaaacaga cttaattgag gatactgata catatgggtg agttagttgc
    12421 tcgagaagcg ctggagcgcg tgtatgggta tgcactgagc agagggatag gccagggcaa
    12481 ctgtgtcgcc gaactcacca aggtgctcgg gctgcacgca gccgacatcg agtccacgat
    12541 ccaacaactc ttaaagatgg gactgttgcg cgaactgccc aaccaggaga tagccgcagt
    12601 gccccccgag gaagcggtga gccggctggt cggcccgctt gagcgcgagg tgcgtgcgcg
    12661 acgcacccgg atcgaggaga cgcggagcct gttgatgtcc ttcctccctg tcttcgaggt
    12721 cagccttgcc gcacgccaac agcccaggcc attcgagttg ctggaggaat tgtccgtcgt
    12781 ccgggcggcg atcgctgagc tggctgccgc agcccaggag gaaatcctca cggcccagcc
    12841 tggcggcgcc cgccaggaga gcatcctcga agaggctgca ccgcgcgatg aggccgccct
    12901 cgcgagaggg gtgcggatgc gcatcctcta ccagcacacg gcgcgcttca gtctggggac
    12961 cacggcctac gtagaacgcg cacagaacgg cggcgcccag gtccgcaccc tggacgacta
    13021 cttcccccgc tttctgatct tcgatcggaa aaccgccgtg ctcaccgtcc tcggccaccc
    13081 tcaggcggcg ttgctcgtcc gcgaacccaa cgtcgtggca ttcatgattg agatgtacga
    13141 gcggatgtgg ctcaccggcg acccctacac cgccgatcac ggcaggcgca gcgagatctc
    13201 cgatgacctc aagcaggcca tcgtccggct cctggtcaaa ggtatgaccg atgcctccat
    13261 cgcgacccga ctcggtatgt ccgtacgtac ctgccgacgc catattgccg acctcatgac
    13321 cgaactgggc gcgcagagcc gattccaggc cggtcatctg ctcgccgccc gtgagaccaa
    13381 tcccgagtcg cgggtggagt gcgatctctg atcggttcga cccctcgagg ccagttcccc
    13441 aggggtccgc acgtcacggc accgcaaccg agtcatcccc ggtcccgcct acagccgtgt
    13501 ccgcgttgca caccctctcc gaacagcaca gttagagcga acgggtgaat gccgagtcgc
    13561 ccgccggacg ggccagccaa gtggagaaag gcgccccggg atgggacggt gtcttgggtc
    13621 cggcctccag ttagcggttg cgcgccgtcg ccgcctccag ccaagcaggg aggcacccga
    13681 cgcgcgctgt tgtgcgggga cttggggtgt gacgttggtc cgtgtcgctc gcgcagcccc
    13741 ttcgctgtgg gcggcctacc tccaagccag cgcgtagacc aggcagacga ggctcgctcg
    13801 ctccggcccc agaagttgcc ctcggtgccg tccagacgct ggtgatcgcg ttacaccgcg
    13861 gcccgcccga cgccgccgag accgcatccg agcacacctg tgaatcctgc ggagccccgg
    13921 ccgcatccgc ttgcgcggcg acgatcaccg cacctggatg caggctagct gcgacacctg
    13981 ccgtacgcgc ccaccgcacc gggccgagcc gacggacggc aaagcaatca cctcttagca
    14041 gccaccggcg ggacgccgac aacaccgatc ttctcgacgt cataggcaac cccgcccggg
    14101 tcacacagaa cccgttccgg taagtcgcgg gcggctttat acccggcgat ccccggttaa
    14161 ggaaaccggg gattctccgc accattgatc ctcccactgt ccgctccgtg gaaggacctt
    14221 tgtgcccgaa gccctacgtt cacctatcgt tccagctggc acactcacct cacacaggca
    14281 tgatctcagt cacacaatcg tgcaggaaaa gggacacgat gaatcgtcgc aacgcgacac
    14341 gcacgcaggg cgccggcctc gtgtaaagcg acacgacctg cgtgggacac ggtgtctgcc
    14401 gacacaaagc ggaacggcct ggtgccgctc ggctacgaca ccgccctggc cctggagatc
    14461 atcccgttca agggcggcac caagggctac ctggccagtc ccgagcagcg gcgccggtac
    14521 ctggaggcgc tgaacccggc ggcccgcgcc accaccggac agcccatcag ccagcatctg
    14581 ggcccttacc tcctggtcaa gggcttgttt ttcctcgcgc tgatgaagcc caccgacccc
    14641 gcgcgcatcg acaagcacct caagtggcaa taccgccggc acctattcat ggaggtcctg
    14701 gagcagtatg agcgcaccgg agcaatcgac cccgcccgct tccccaccct cgacgacttc
    14761 gccgctcggc acagcgctcc cggccatccg tgaccgcgac tacctcctcg accgcgcggg
    14821 cgtcatcttc aaggtgatcg gcgatgtcca cccgggcacg cactggttgg ggtatgtgaa
    14881 gtaccccccg actcgcgcgg cgaccggacg ctgttcggcc gcacgtaccg gcaaaacacc
    14941 gtcgtatcca aagccttcgg cctcttagtc gaccggcccg agtgctacgt ctactcgccc
    15001 gccgtcggct gcgtcatcac cggcgtgccc cgcgaactgc tggacggctc ggcggtcagc
    15061 aaagacctgc tggccatcat cgactgggtc gtggacgccg gcgccgccga cgttatcggc
    15121 gtcaccggct cgttcctggt cggggcgtgc aacgcccgct ccgacatcga cctggtctgc
    15181 tacggacccc gcggatacga agccgcccag gccctgttcg ccgagcgggc gctgatccag
    15241 ccgtacgagg gtgacgccca gactcggctg tacatccgac gggcgaagta catgacaggc
    15301 agctcgttcg acgccctgat gcggcaggaa gcgcgcaaac tgcagggact gaccaccggc
    15361 gccggcgcac acatcaactg cgagcccctg cgcgccgacg gcgaccgaac cctcgccggg
    15421 gtggtcgccc aggaagtcgg cgcgatcagc gtgctggccc gcgtgaccga ccacaccgag
    15481 ggcctcgcaa cgcccgccgt ctacggcatc gcggtggaca ccgtcatcgg gtcagcggcc
    15541 cggaaaggag ttgtccaggc tgaggagcgg ttgttaccgt cacgccagcg cgagagacgc
    15601 gtgctcagcg ggacagggag gttgatgaat atggctgccg tcggccctca tcagcatgcc
    15661 ctcgtccggc ccgcgcgata acagagcgcg gccgggtcgt tccaacgacc aggagagaca
    15721 cgtgtcttcc tcttcttcgg gtctgtacgg tctccggtgt aattgatgat caaggaagag
    15781 acatcaagtg actgacaccg tgaccgagtc cgtggccgac gatgaccagg cggaaccgtc
    15841 gctggagagt gcggcggtcg agcagaagct gatcgaccag ctcgtcgagc aggcccggag
    15901 caaggggctg cagctgaccg gcgacggtgg gctgctgcag cagctgacca agacggttct
    15961 ggagtccgcc ctggagggcg agatcaccga ccatctcggc tatgacaagc acgacccggc
    16021 gggcaaggac ggcggcaact cccgcaacgg aacccggtcg aagaaggtac tgaccgacat
    16081 cggcccggtc gagatcgacg tgccccgcga ccgcgagggc tccttcgagc cggccatcgt
    16141 caagaagcgg cagcggcgcc tgaccggcgt ggacgagatg gtcctctcgc tgtccgcgaa
    16201 gggcctcacg catggcgaga tctcctcgca cctggccgag gtctacggcg ccgacgtgtc
    16261 caagacgacc atcaccgcga tcaccgacaa ggtgatggac ggcatgacgg aatggcagaa
    16321 ccgcccgctc gaccgcgtct atccggtcgt cttcattgac gccatcaacg tcaagattcg
    16381 cgatggccaa gtggcgaaca ggccgatcta cgtggcgttg gcggtcaccg ccgaggggca
    16441 ccgcgacatc ctcggcctgt gggccggcga cggcggcgag ggtgcgaagc actggctgcg
    16501 ggtgctctcc gagctcaaga acaggggcgt cgaggatgtc ctcatgctgg tctgcgacgg
    16561 gctgaagggg ctgcccgacg cggtcggcga ggtctggccc cgaactgtgg tgcaaacgtg
    16621 tgtggttcac ctcctgcggg cgtcgttccg ctacgcggcc cgccaggact ggggcaagat
    16681 cgcgaaggcg ctcaagcccg tctacaccgc gccgagcgag gacgcggcga cgacacggtt
    16741 cctggaattc gccgaggtct ggggaaagaa gtatccggcg atcgtccgtc tctgggagtc
    16801 cagctgggcg gagttcacgc ctttcctgca gtttgatgcg gaaatacgcc ggattgtgtg
    16861 cacgaccaac agcatcgaga gcgtcaacgc ccgcatccgc aaggccgttc gcgcacgcgg
    16921 gcacttcccc acggaacagg ccgctctcaa gtgcgtctac atggccgtca tgagcctcga
    16981 cccgaccggc tccggccgca aacgctggac catgcgctgg aagggcgcga tgaacgcctt
    17041 cgacctggcc ttcgacggcc gcctcaccgc aggccaactc tagccacacc aaccccagtt
    17101 acaccgctag ctttacagac cctccactcc cgacgccgtc atcgcgggca tcctcaaccg
    17161 ccaacaacgc cgcacagcac ggggattgtc atacaccgcc agtagagtcc agtccctgcg
    17221 acaccactgg aacattgact gccaccagaa gaacccgcaa cagcaggaag gagagctggt
    17281 caccgtggcc caagccgccg ccgacctcgg cctggccccc tccaccctgc accgctggct
    17341 caacgacggc ttcatcgcag gcgagcagat caccccaggc gccccctggc gcatccgcct
    17401 caccgacgaa ctccgggccc tgttcgtcga taccgccccc gcgggatggc tcgccatgct
    17461 cgaggccacc ctcgcccacg gtgtctcccg ccagaccctg ttgcagcgtg tcaagcgcgg
    17521 cgagctccgc gccgtccacg tccgcaccgg ccgcagaaag ggcctgcgca tcgaaccgcc
    17581 agcccctcag aacagcctct tctgacatcc acaatcagcg aaaggagcag tgtgacgatg
    17641 cttccaagca agccttgatg tcgccctcga tgtcccactc gtagtttgac ggcttgctgg
    17701 tgcagtggtg gatttcggcg atggcatcct gagcccgccg gccaggccga tacccgtaac
    17761 tggacgggta gaaatcgacc tcgaagatcg gctccagaac cagcttgagg gccatctgcg
    17821 ccacccggtc acgcagagtc gggataccca ggtaacggac cttgccgttc ttcttcggga
    17881 tcaccgcctg cttgaccgga agcgccgtga aggacccgtc tttgagggag gagcgcagct
    17941 cctccagaaa cggaatcact ccgtgacgtt cctcgacgtg ataacgggtt aacccgtcca
    18001 cgcctgctgt cctggcaccc cggttgccgg acacccgttc ccaggccacc agcaatgtgg
    18061 cccggtcaca gaccaagttg aatacatcct tgaaccgtcg atgcggctca ttccttgccc
    18121 atcggtgcag cttgagctga tgatcgagta cccgccgctc ggccgccata ctgcccggcc
    18181 aagatatcgg cggtgcgtcg ttgttcaaca acgttcctcc ccgacagcag ctctgctgct
    18241 atcacgctgt cgccctttcc cgtgtgaccg gctttcccgg actctgagta ctacggcgac
    18301 tccgccacga tctggcatca tcagcgggcg ttgcgcctgc ccgccgtccg accggctgcc
    18361 ggacgggaag ggcgatgcca gatcgcttcc cacgttcact gagaatctct gcgacggctt
    18421 cggtgcccgg ctttaccccg gcagcatcgc cacggaccgc atatcgcagt cttggtccgg
    18481 gcctcccggc gcccacaggc taaagacgcc ggaagaggag aggccaccgg atagagcact
    18541 ctccagcact gcggcgcggc ccatccacca gattcggcag accgctgacg actcacgggg
    18601 cttcaaccac cgattcagtt tccttacacc cattccgtct tcgcttgcgg gcacgaaccg
    18661 cctggtggtg tcgattcgcc cctacgttgt cgaggccgct tccggcgtca cccccaaccc
    18721 ggggatccac ctgcctccag cttcaaccag tcactgcgat gaccagcggc gggttcctcc
    18781 tcccgctcga ttcctcagcg cctcgtggcg cacagcccgt ctcatcgatg atcagaacac
    18841 cgccaggctc gccgaggcgt tcggcggtat atgcctgcac atcgtcgcgg atctcgtccg
    18901 cgttccagcg ggcccggttg aggaggttct ggagcccatg aggtgtgccg tgacctgcat
    18961 gttcagccag ctgccagctg ttcttccgcc ccaccggacc gagcagggcc cgcacgtagt
    19021 cccgcatccg ccgccgcaga tcagcccggc cgaaccggtg accaacccgc agcagcacct
    19081 cctcaagctc cccggcccac acctcgggct gcatatcatc ttgcacgatc agcacaacag
    19141 cgatcacact cagccggtca cgaactcccg ccacctgact gccagtcagc tcgctacact
    19201 cagaaacaga tccctgacca gcaggaatag caaactgcaa ctggagtaat agaacgcggc
    19261 caggttgaac gcggtgcgca agaggtttac tccgtgtagg tggtgacgtc gttgatgaaa
    19321 actttaggct cgccaacggt tcgcgtatat cctgaaatgt ctatttcact ggactccttc
    19381 tttgttagtc caggctcaat gttccggata tcgaaggtct gcgcaaatac cggagtttcg
    19441 ccattgctga tagcgacatc gatgctgtag ctcagttcct tctcagttgc gttgctcgcg
    19501 gtgacgacga ggttgatcac cgacacttcc accgtcgccg cgaccttgac atcgccgagc
    19561 gtgaccgtct tggtcttccc gtcatagttg acgaccggag tcggctcctc atccggcgtc
    19621 acggtctgca ccggaggttt agttgtggca cctggtgatt cttcggaggt gatcacacat
    19681 ccggaagcca acatcagtgc aggcagtacg acatagaggg tccatttgat tcgcacacaa
    19741 gcctcccact ggggggatga cattatcatc atgattctgc cacccatcga tcagcagcgc
    19801 agtagagacg tgaaaggtat taagtcgtga catgtgaact ttcggcatgg agtcagatca
    19861 ctgagtggat tcgcgagaac gcaccgcgct cctacgcaca gctccaggaa ggtgcgacat
    19921 cggatgcctt ggcgcacact agagcgcgac tgggaacacc gctgcctgaa gagctgtcat
    19981 ccatgctgca catgaacaac ggcgtgcagg tcgaccccaa tgatccggac ggcatgcgtc
    20041 ctcgccggtc cggtgaattt gtctctgact tctacagcat cctctcgacg catttgatca
    20101 cccgtgtcaa tgagcacatg aatgctgtct acaacggcgg ggaacaagac ggcgagtgga
    20161 agcaccattg ggttcccttc gccgtcgaga gcgactggct atacggcctg ttcatcgacg
    20221 gcaccaccgg ggccgtcggc gaatggtccg acggcggacc catcgaagag aacgtctacc
    20281 cgtcgctgtc agcctttctg gaagagtcgt tccagctgat acagagccgt gccggtatct
    20341 ataacgagat gatcgtctgg gacatcgacg acctcgacca ggaggatctt gaccaactca
    20401 cctgaccgca aacacactgt ggtcccacca attcccttgg tggggccaca gttttatgct
    20461 ctgttacagg gtgaatccgt cgaggtcgac ccagtactgg tcgtcctgca taagacgctg
    20521 ctccttgatg aagtcaccga acggacgcat ggactgagtg ttttgccagt tcgacatcga
    20581 ggaccggcca catggctcgc tccagttcgg cgccgggtag tcggggcgca ggtggatgga
    20641 gatcgtgtcg tcgctgttgc gcttgatgta ggtctgcacg cactcggcgc cgctgtagtc
    20701 gacggggttg gtgccgccgt tggagttcgg gttgccgccg ctctggtagg cgttggcgaa
    20761 ggcgaactcg tcacagctga tggagtcggt tgttccccac aggtcggtga acaggccggt
    20821 tcccgcgtac gtgcgccact tccgcttgca gatcttctga cggttgcgct tgtgctgggt
    20881 cttgccgctg ccgtcgtcgg acatcttgtc ggcgaggtac ttcagcggct ttccgctgct
    20941 gcgctttccg tagacgattt tcgtcttgtc ccacatcagg gcgatgtgtg ccgctgcgcc
    21001 gcggaacttc ttggagttca tgacgtaggt cggcttgtag ccggagaaga cacagccggt
    21061 tccggcgttg atgacctggt tgtcacagcg gatgtccagt tgggacttct cgacttcgag
    21121 tgggttccta atcgggtcac cgttggtcga gccggcgaag gtccagtacg gggtgattgt
    21181 gttcgtggtg tcctggctcg gcgtccactt catgcgtgtg gtgatggtcc tgcggagtgt
    21241 gtctcccttc ttccacgtct tggatccgtc ccagttcgtg ctggtgatgg cgcagtagcc
    21301 acggcatttg gcccggtagt ccaggttgac cgtgttcatc gcgccgttca tcgacttcaa
    21361 ggagagcgtg gtgacctgcg agaactcggc gctcttgggg tcgaggtaga tcgtgttgta
    21421 gtagtcgaag ctcgctgtgc cgtctggttt cccgttctcg aagtgcgtga cgtacagagt
    21481 gtcgtggatg caggcgttgg cgcgcttgcg ttcgatcgac accgaggcga tcgagcacga
    21541 ggtcggactg ctcagcgaca tcgtgctggc gctggtggtg gatctggttc cggggagtgc
    21601 agggaagaag cctccggaga tttcctctga cggctcgatg ggttccgggt ccgccgcgct
    21661 cgggttgggc agcgggtagg tgccgaactt cgtgccgttg taggtgccgg gcacgaaggc
    21721 gatggcgtcg aaggcgatgt ccgcgtctcc agtgccgccg ttgaagttgt ccagccggac
    21781 ctcgggcgtg gtgttcttga agtagtaggc gcccaggtcg acccacttgt tcgactggtt
    21841 ggccttctgt gagatcgtcg cgtcgatctc accctcgtcg gttttgatcc agtaggtggc
    21901 cttcttggtc tgtgccccgt ggtcggggat gtgcgcgaag accttggcct ggccggaggt
    21961 gttgttgatc ggaccgttca gcttccacgt gccgg
//
