LOCUS       NZ_CP086322            22717 bp    DNA     linear   CON 26-NOV-2024
DEFINITION  Streptomyces halobius strain 3_2 chromosome, complete genome.
ACCESSION   NZ_CP086322
VERSION     NZ_CP086322.1
KEYWORDS    RefSeq.
SOURCE      Streptomyces halobius
  ORGANISM  Streptomyces halobius
            Bacteria; Bacillati; Actinomycetota; Actinomycetes;
            Kitasatosporales; Streptomycetaceae; Streptomyces.
REFERENCE   1  (bases 1 to 9239126)
  AUTHORS   Wen,Y., Zhang,W. and Liu,X.G.
  TITLE     Streptomyces nigrumlapis sp.nov.,an antimicrobial producing
            actinobacterium isolated from Black Gobi rocks
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 9239126)
  AUTHORS   Zhang,W., Liu,X.G. and Wen,Y.
  TITLE     Direct Submission
  JOURNAL   Submitted (04-OCT-2021) Northwest Institute of Eco-Environment and
            Resources, CAS, Chinese Academy of Sciences, Donggang West Road 320,
            Lanzhou, Gansu 730000, China
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method :: GS De Novo Assembler v. FEB-2021
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 241.26X
            Sequencing Technology             :: PacBio Sequel
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_023277745.1-RS_2024_11_26
            Annotation Date                   :: 11/26/2024 03:43:17
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.9
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 8,438
            CDSs (total)                      :: 8,346
            Genes (coding)                    :: 7,837
            CDSs (with protein)               :: 7,837
            Genes (RNA)                       :: 92
            rRNAs                             :: 6, 6, 6 (5S, 16S, 23S)
            complete rRNAs                    :: 6, 6, 6 (5S, 16S, 23S)
            tRNAs                             :: 71
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 509
            CDSs (without protein)            :: 509
            Pseudo Genes (ambiguous residues) :: 0 of 509
            Pseudo Genes (frameshifted)       :: 193 of 509
            Pseudo Genes (incomplete)         :: 418 of 509
            Pseudo Genes (internal stop)      :: 17 of 509
            Pseudo Genes (multiple problems)  :: 113 of 509
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 18:33:41
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 6082931
            Orig. end                         :: 6105648
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP086322.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            This genome has a base modification file available.
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..22717
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="lassopeptide"
                     /region_number="28"
                     /rules="(PF13471 and Asn_synthase or micJ25 or mcjC)"
                     /tool="antismash"
     cand_cluster    1..22717
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PF13471 and Asn_synthase or micJ25 or
                     mcjC)"
                     /kind="single"
                     /product="lassopeptide"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..22717
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:12717](-)"
                     /cutoff="10000"
                     /detection_rule="(PF13471 and Asn_synthase or micJ25 or
                     mcjC)"
                     /neighbourhood="10000"
                     /product="lassopeptide"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..12717)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="(PF13471 and Asn_synthase or micJ25 or
                     mcjC)"
                     /neighbourhood="10000"
                     /product="lassopeptide"
                     /protocluster_number="1"
     misc_feature    156..165
                     /note="TFBS match to ToxT, Regulator of MSHA biosynthesis,
                     confidence: weak, score: 15.27"
                     /tool="antismash"
     gene            430..1308
                     /locus_tag="K9S39_RS27640"
                     /old_locus_tag="K9S39_27775"
     CDS             430..1308
                     /GO_component="GO:0005576 - extracellular region [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006605292.1"
                     /locus_tag="K9S39_RS27640"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="K9S39_27775"
                     /product="LPXTG cell wall anchor domain-containing protein"
                     /protein_id="WP_248866013.1"
                     /transl_table=11
                     /translation="MTKKTRLRVARIAAGAVIAAGASLTAAGAASAAGPGDSGPSQDGG
                     FIGGIIGGLIGGGDSGGDTGGDTGGTDGGVTGGDTGGTDGGVTGGDSGGEIGGTDGGTD
                     GGVIGGTVGGTDGGVTGGDSGGTDGGVTGGDTGGTDGGVSGGDSGGDTGGDTGGDTGGQ
                     NSGGQSGGNNGGNVNGGQNSGGQSGGSTTGGDDTAGTTGGSDTTGGDSTGTGTDNENTQ
                     PVEQPGQGKEQISDTPGPAKQQAKGGELAETGASGTTFLLVGAATMIAGGVGFRVLPRL
                     INKNAGGAAAA"
     gene            complement(1421..1615)
                     /locus_tag="K9S39_RS27645"
                     /old_locus_tag="K9S39_27780"
     CDS             complement(1421..1615)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003975842.1"
                     /locus_tag="K9S39_RS27645"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="K9S39_27780"
                     /product="hypothetical protein"
                     /protein_id="WP_248866015.1"
                     /transl_table=11
                     /translation="MTYDRLVCANCAAPVSEGRCPVCRASRAQLQHQVGGFFTQLNPVM
                     LVALLIALVAVGVLLHQVV"
     misc_feature    complement(1691..1705)
                     /note="TFBS match to IolR, Regulator of the inositol
                     catabolism, confidence: medium, score: 18.31"
                     /tool="antismash"
     gene            1924..2613
                     /gene="ftsE"
                     /locus_tag="K9S39_RS27650"
                     /old_locus_tag="K9S39_27785"
     CDS             1924..2613
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_process="GO:0000910 - cytokinesis [Evidence IEA]"
                     /codon_start=1
                     /gene="ftsE"
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006349025.1"
                     /locus_tag="K9S39_RS27650"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="K9S39_27785"
                     /product="cell division ATP-binding protein FtsE"
                     /protein_id="WP_248866017.1"
                     /transl_table=11
                     /translation="MIRFDNVSKTYPKQTRPALRDVSLEIERGEFVFLVGSSGSGKSTF
                     LRLLLREERASHGAVHVLGKDLGKLSNWKVPQMRRQVGTVFQDFRLLPNKTVGQNVAFA
                     LEVIGKPRGQIRKTVPEVLELVGLGGKEDRMPGELSGGEQQRVAIARAFVNRPMLLIAD
                     EPTGNLDPQTSVGIMKLLDRINRTGTTVVMATHDQQIVDQMRKRVMELEKGRLVRDQSR
                     GVYGYQH"
     gene            2646..3560
                     /gene="ftsX"
                     /locus_tag="K9S39_RS27655"
                     /old_locus_tag="K9S39_27790"
     CDS             2646..3560
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /gene="ftsX"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016572291.1"
                     /locus_tag="K9S39_RS27655"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="K9S39_27790"
                     /product="permease-like cell division protein FtsX"
                     /protein_id="WP_248866019.1"
                     /transl_table=11
                     /translation="MRAQFVLSEIGVGLRRNLTMTFAVIVSVALSLGLFGASLLMRDQV
                     STMKGYWYDKVNVSIFFCNKNDAAAGTNCDKGAATQQQKDDIKAELERLPIVQKPVQYE
                     SSDQAYKHYKEQFGDTPVAGLVTPDQLPESFRVKLKDPTKYDVIKSAFSERPGVQEVQD
                     QRDTVEPLFNLLNGMNLAALVVMALMLIVALMLIVNTVRVSAFSRRRETGIMRLVGASS
                     FYIQMPFILEAAIAGLLGALFACVLLVGGKYILVNNWLADKIQVINFIGWDSVAAVLPL
                     VLLIGLLMPALAAFFALRKYLKV"
     gene            3629..4843
                     /locus_tag="K9S39_RS27660"
                     /old_locus_tag="K9S39_27795"
     CDS             3629..4843
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_S41"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016572290.1"
                     /locus_tag="K9S39_RS27660"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="K9S39_27795"
                     /product="S41 family peptidase"
                     /protein_id="WP_248866021.1"
                     /sec_met_domain="Peptidase_S41 (E-value: 1.2e-40, bitscore:
                     137.7, seeds: 119, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSGPCSYDRPRRIRRGAALTLVFASVLATGAATGTWSDSAEGAAG
                     ARGPGPTAAGLAPTDRTADRTDVERAASQAFEDGKSGSKAADEVVSRSGDRWSAIYTPG
                     EFEDFQRQLDGRYIGVGLWLRQAAGGRIVVSRVQPDSPAARAGIAVGDRLRAVDGRASQ
                     GRPVTEVVGRLRGDAKGPHGPSAAAGTPVELDLQRGDRRWRTTLYRTRLRTQNVTTARP
                     AGADGPTRIKITAFAKGTGEEVRRAVRGASPHGGLLLDLRGNTGGLVTEAVASAAAFLD
                     GGLVATYDVRGSQRALYAEPPGNPRIPLVVLVDGGTMSAGELLAGALQDRGRAVVVGSP
                     TFGKGSVQMPRELPDGSVAEVTVGHYRTPSGRAVDGRGITPDLIVGDGAEKRARTVLSG
                     LGTGA"
     gene            4862..5374
                     /gene="smpB"
                     /locus_tag="K9S39_RS27665"
                     /old_locus_tag="K9S39_27800"
     CDS             4862..5374
                     /GO_function="GO:0003723 - RNA binding [Evidence IEA]"
                     /codon_start=1
                     /gene="smpB"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016572289.1"
                     /locus_tag="K9S39_RS27665"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="K9S39_27800"
                     /product="SsrA-binding protein SmpB"
                     /protein_id="WP_248866022.1"
                     /transl_table=11
                     /translation="MTKQTKDTGKGKDKTPGRRLIAQHKKARHDYHILDTYECGLVLTG
                     TEVKSLRQGRASLVDGFIQIDRGEAWLHNVHIPEYAQGTWTNHSARRKRKLLMHRVEID
                     KLDSKSQETGHTIVPLSLYFKDGRAKVEIALARGKKEYDKRQTLREKQDRREAERAISA
                     ARRRQRA"
     tmRNA           5534..5903
                     /db_xref="RFAM:RF00023"
                     /gene="ssrA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00023"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /locus_tag="K9S39_RS27670"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /old_locus_tag="K9S39_27805"
                     /product="transfer-messenger RNA"
     gene            5534..5903
                     /gene="ssrA"
                     /locus_tag="K9S39_RS27670"
                     /old_locus_tag="K9S39_27805"
     gene            complement(6035..7399)
                     /locus_tag="K9S39_RS27675"
                     /old_locus_tag="K9S39_27810"
     CDS             complement(6035..7399)
                     /GO_function="GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1020: major
                     facilitator transporter"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018542339.1"
                     /locus_tag="K9S39_RS27675"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="K9S39_27810"
                     /product="MFS transporter"
                     /protein_id="WP_248866023.1"
                     /transl_table=11
                     /translation="MILFLGARPVVPRPAVLRPVAPRSVVPRPVTAPPVPPSPPVRPSP
                     RVRRHGRGVTLTAPYRRIFAVPGTRAFTAANLLARLPMGMLSVSAVLMIAGTRGSYALA
                     GAVVATGLTATALVGPLTARLIDRYGQSRIAVPATVIAALGSLSLLLCVHYDAPAWALF
                     ASYIATATTPNTGGMSRARWAHLFRGDPAARHTANSFEQAADELCFMLGPVLATLLCTA
                     FLPEAGTAVAAALLLTGVLLFAAQRGTEPPVAPRTTGRPRSPLRLPGLSPLLLTFLATG
                     AVFGSLEVVTIAFADVHGVRPAAGGMLALQAAGSCAAGLLYGLLRPTGPAGSRFLGCVA
                     AMSALMPLPLAAASTGSLPALAVALLLAGMATAPTMVTGMGLLQSRTPAAQLNEGMTLA
                     VTALLAGIAAGSAAGGWAVDHLAGPGPAYVMPATAAALALAVTMSRRKGLRSRAR"
     gene            7521..8492
                     /locus_tag="K9S39_RS27680"
                     /old_locus_tag="K9S39_27815"
     CDS             7521..8492
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1014: LysR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018091248.1"
                     /locus_tag="K9S39_RS27680"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="K9S39_27815"
                     /product="LysR family transcriptional regulator"
                     /protein_id="WP_248866024.1"
                     /transl_table=11
                     /translation="MPYDIAPRLLRAFTAVADELHFTRAAARLYVAQQALSRDIRRLER
                     ELGADLFVRTTRQVALTAHGARLVPYARRVLAAHDELAAAFRATPERPLLVDVGVPIGT
                     AHRVLEEARRRVPDSCELVARFHSGLTGAAEELRAVRLDVSFGRFAALPPAVRAGLDHQ
                     PVRLEPMAVLLPEEHRLAARPTVPLAELTGETLYAAAGNPQAVEWTDLAARLFEGRGIA
                     MAAPFPEIEGSQEFTRVVRKQGWAVLASVEFIDVPGMVLRPVVDPVPLSPVGMVWRRGL
                     RHPGLDALRAAARELGERDAWLAPPGDGWWLPEADATAMGLR"
     gene            8675..9211
                     /locus_tag="K9S39_RS27685"
                     /old_locus_tag="K9S39_27820"
     CDS             8675..9211
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018091249.1"
                     /locus_tag="K9S39_RS27685"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="K9S39_27820"
                     /product="DUF4232 domain-containing protein"
                     /protein_id="WP_248866025.1"
                     /transl_table=11
                     /translation="MRRRSLLAATAAALILTVFGLGLVGCGSPRMAALHADCTTKDLKW
                     KLAVLKKKPHSTHREARLTAVNEGPGACVFRGFPVFEVHVGKGPESDGKGRGQTMPIDL
                     RRGGTVTTSLRYKDSDRGTPSAACMVSNDTAVVAAPRDTTGGRAIAARDETGGRARMTI
                     CEDTVWMSPPKEIAE"
     gene            complement(<9261..9377)
                     /locus_tag="K9S39_RS43110"
                     /pseudo=""
     CDS             complement(<9261..9377)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF040183.4"
                     /locus_tag="K9S39_RS43110"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /product="Scr1 family TA system antitoxin-like
                     transcriptional regulator"
                     /pseudo=""
                     /transl_table=11
                     /translation="MRTCAELPGVQIQILPLNCPTHARLDGPFVLLETPDHQR"
     gene            complement(9396..9893)
                     /locus_tag="K9S39_RS27690"
                     /old_locus_tag="K9S39_27825"
     CDS             complement(9396..9893)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF040183.4"
                     /locus_tag="K9S39_RS27690"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="K9S39_27825"
                     /product="Scr1 family TA system antitoxin-like
                     transcriptional regulator"
                     /protein_id="WP_248866026.1"
                     /transl_table=11
                     /translation="MEVLGAIMALFRANAGLTQRELGNLVSVSEQTIAFIEQGRRALLP
                     RPAVEIDRILKTGGALKVGVEKLPKREKFPVWAEEFMDFEREAIALCWYENVVIPGLLQ
                     TSDYARATLRSGVIPHLTEEEIEQRVTTRQDRQQIVHKPKPVSASFVIAEPSCWAGSVD
                     PR"
     gene            complement(10001..10411)
                     /locus_tag="K9S39_RS27695"
                     /old_locus_tag="K9S39_27830"
     CDS             complement(10001..10411)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lassopeptide: PF13471"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018090021.1"
                     /locus_tag="K9S39_RS27695"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="K9S39_27830"
                     /product="lasso peptide biosynthesis B2 protein"
                     /protein_id="WP_248866027.1"
                     /sec_met_domain="PF13471 (E-value: 3.8e-24, bitscore: 83.9,
                     seeds: 84, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSVPLSIDPRAHLTLTERCTARCCVAAARLLARRSPRTICRVLDR
                     VRRGARPATAPDALRARHAVVTVNARCTGQGCLQRSLATALLCRTRGRWPQWCTGVRTE
                     PFRARAWVAVDGHPIGEPDDTRLYQPLLSIPR"
     gene            complement(10408..10671)
                     /locus_tag="K9S39_RS27700"
                     /old_locus_tag="K9S39_27835"
     CDS             complement(10408..10671)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lassopeptide: Stand_Alone_Lasso_RRE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF05402"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014056407.1"
                     /locus_tag="K9S39_RS27700"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="K9S39_27835"
                     /product="lasso peptide biosynthesis PqqD family chaperone"
                     /protein_id="WP_248866028.1"
                     /sec_met_domain="Stand_Alone_Lasso_RRE (E-value: 2e-21,
                     bitscore: 74.7, seeds: 25, tool: rule-based-clusters)"
                     /sec_met_domain="PF05402 (E-value: 2.7e-11, bitscore: 42.5,
                     seeds: 461, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPLSVSLAPDITSTRTPGGMILLNTRTGRYWQLNETGALILEHLL
                     AGGSCTSAVAELRIRHPEAADRVEADTKALLSSLKSAKLVTS"
     aSDomain        complement(10414..10656)
                     /aSDomain="Stand_Alone_Lasso_RRE"
                     /aSTool="RREfinder"
                     /database="RREFam.hmm"
                     /description="Stand-alone RRE protein in a lasso peptide
                     cluster"
                     /detection="hmmscan"
                     /domain_id="rrefinder_K9S39_RS27700_Stand_Alone_Lasso_RRE.1
                     "
                     /evalue="6.70E-24"
                     /identifier="RREFam002.1"
                     /label="K9S39_RS27700"
                     /locus_tag="K9S39_RS27700"
                     /protein_end="86"
                     /protein_start="5"
                     /score="74.7"
                     /tool="antismash"
                     /translation="SLAPDITSTRTPGGMILLNTRTGRYWQLNETGALILEHLLAGGSC
                     TSAVAELRIRHPEAADRVEADTKALLSSLKSAKLVT"
     gene            complement(10747..12717)
                     /locus_tag="K9S39_RS27705"
                     /old_locus_tag="K9S39_27840"
     CDS             complement(10747..12717)
                     /GO_function="GO:0004066 - asparagine synthase
                     (glutamine-hydrolyzing) activity [Evidence IEA]"
                     /GO_process="GO:0006529 - asparagine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lassopeptide: Asn_synthase"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1177: asparagine synthase (glutamine-hydrolyzing)"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018542336.1"
                     /locus_tag="K9S39_RS27705"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="K9S39_27840"
                     /product="asparagine synthase-related protein"
                     /protein_id="WP_248866030.1"
                     /sec_met_domain="Asn_synthase (E-value: 2.7e-30, bitscore:
                     105.1, seeds: 78, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDFLVLPDHPAADRLIACLHRRPTLRIVPYASGRPWIVGHWSRDE
                     TITARIGPRRIALLGTTSATRDGLTRLLRRLTSLDDLGDHLRAHLGDLPGSFFLMAAFG
                     PEVRCQGSLSTYRQLHHTDIGGIAVAGNRPQNLAALGCEAAKTGLDRAPHLGTVDEETL
                     AARLLTPFAPLPLALRQAWRSVHAVPPGHYLTFAPNGRHVVRRWWQPPAPDTPLPDAAE
                     AVRDALSAAVRVRTRHGTLSADLSGGMDSTSLCFLAARAPHTRLITTAWQCRDPANDDN
                     LWSARSAAHLSTGDHTGGGNVGEHLSLPYAEVPTWYTPPSDPGHTDPAGPLAAIRESAR
                     LSHHARLVAERGSRLHLVGVGGDELFSPRPVALDPRPAALNPRPVALHSLARRDLRTAR
                     QPLRARRLGRWTLPDPLRPLRDSLHTLWNGDSYPQWLATCTEQHGTTGAAWEIAPSMPP
                     WAHPDAVTTVRRLLREAAAEAPEPYAALRAQHETVRAAVRAGEIVRGIDAVASAQGVAY
                     EAPFLDDAVIKAALTVRLAGHTETGAYKPLLATAMRGLVPDAVLGRGTKGDHSAEVYAG
                     LRRHRRALSALCDDSLLARLGLIRPDALRHVLTSLHPHTHTLLPLDPTLAAEYWLRSLP
                     YGQLPPPAAVTPASATATAAP"
     gene            complement(12841..13122)
                     /locus_tag="K9S39_RS27710"
                     /old_locus_tag="K9S39_27845"
     CDS             complement(12841..13122)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF033521.1"
                     /locus_tag="K9S39_RS27710"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="K9S39_27845"
                     /product="lasso RiPP family leader peptide-containing
                     protein"
                     /protein_id="WP_248866032.1"
                     /transl_table=11
                     /translation="MQDLMQELLQELQQPREHAGYGGHVGYGEHAGYTEQVEQAECGGD
                     VEHAECGGDVEQVEYEVPELADVGDFAELTPGLVGWHHDAFGGHFWQE"
     gene            13414..14823
                     /locus_tag="K9S39_RS27715"
                     /old_locus_tag="K9S39_27850"
     CDS             13414..14823
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006605303.1"
                     /locus_tag="K9S39_RS27715"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="K9S39_27850"
                     /product="NarK/NasA family nitrate transporter"
                     /protein_id="WP_248866034.1"
                     /transl_table=11
                     /translation="MTTEAARTGGSSGRRGGHWIEHWDPENETFWAESGERIARRNLWF
                     SVMSEHIGFSVWSLWSVMVLFMGPEYGLAPADKFFLVAVTTLVGAVLRVPYTFAVAKFG
                     GRNWTIISALMLLVPTTAAWFVMEPGTSYGTFLLIASLTGIGGANFASSMTNINSFYPL
                     RKKGWALGMNAGGGNIGVPVIQLVGLLVIGTAGAAHPHIVLGIYIPLVVVSAVCAALFM
                     DNLAPVKNDTGAAKDAAREPHTWIMSLLYVGTFGSFIGYSFAFGLVLTTQFDRTPLQAA
                     SLTFIGPLLGSLVRPVGGQLADRFGGARITLWNFAAMGAATLVVIFAAVQESLPLFLVG
                     FIALFVLTGVGNGSTYKMIPGIFQNKALERGLTGEAAAAYGRRLSGASMGLIGAAGAVG
                     GLGINLAFRQAFMTTGSGTPAFVSFLAFYALCLVVTWAVYLRRPAGARSAAEPGTGEAD
                     EEAPRPVYAEV"
     gene            15082..16281
                     /locus_tag="K9S39_RS27720"
                     /old_locus_tag="K9S39_27855"
     CDS             15082..16281
                     /EC_number="4.2.1.75"
                     /GO_function="GO:0004852 - uroporphyrinogen-III synthase
                     activity [Evidence IEA]"
                     /GO_process="GO:0006780 - uroporphyrinogen III biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010986525.1"
                     /locus_tag="K9S39_RS27720"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="K9S39_27855"
                     /product="uroporphyrinogen-III synthase"
                     /protein_id="WP_248866036.1"
                     /transl_table=11
                     /translation="MHQHQQVQKERDHREQQPATPAPGVRPLDGFTVGVTAARRAEELG
                     TLLERRGAQVLHAPALRIVPLPDDDGLLAVTRSLIEDAPDIVVATTAIGFRGWIEAAEG
                     WGLGEDLLDRLAGVELLARGPKVRGAIRAAGLTEKWSPASESMAEVLDRLLAEGVSGRR
                     VAVQLHGEPLPGFVEALRADGAEVVGVPVYRWMPPEDIGPVDRLLDAVLGRGVDAVTFT
                     SAPAAASLLRRAEERGIRDEVLAALRREVLPVCVGPVTALPLQAHDIPTLQPERFRLGP
                     LVQLLCRELPGRVRPLPVAGRWLEVRGHAVVVGGELRPVPPAGMALLRALARRPGWVVS
                     RADLLRALPGAGRDEHAVETAMARLRVALGAPKLIQTVVKRGYRLSLDPHADTDKYGGA
                     "
     gene            complement(16451..17227)
                     /locus_tag="K9S39_RS27725"
                     /old_locus_tag="K9S39_27860"
     CDS             complement(16451..17227)
                     /EC_number="2.1.-.-"
                     /GO_function="GO:0008168 - methyltransferase activity
                     [Evidence IEA]"
                     /GO_function="GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018091254.1"
                     /locus_tag="K9S39_RS27725"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="K9S39_27860"
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="WP_248866038.1"
                     /transl_table=11
                     /translation="MSPKSLLKNRASLTHKIGYAVRNPARITPYVKRTARDTWLRLKHP
                     DHVDYYRAVMASDTDRNPEAAVGSRSHERWLALGEMQFAYLAEHGLKPGHRMLDIGCGN
                     LRAGWRFIAHLDTGNYYGVDISPDILISAKKTLTTYELQHKLPHLTITRDLKLDFLPAA
                     HFDVVHAHSVFSHSPLPVIDECLAHVGRVLAPGGFFDFTFDRTEGTEHQVLREDFYYRT
                     ETLLNLARKHGLEARFMDDWEKRPHGQSKIRVNNPE"
     misc_feature    complement(17195..17211)
                     /note="TFBS match to GnfM, Regulator of nitrogen-fixation
                     genes, confidence: weak, score: 19.23"
                     /tool="antismash"
     misc_feature    17199..17208
                     /note="TFBS match to ToxT, Regulator of MSHA biosynthesis,
                     confidence: weak, score: 14.19"
                     /tool="antismash"
     misc_feature    17311..17325
                     /note="TFBS match to IolR, Regulator of the inositol
                     catabolism, confidence: medium, score: 19.08"
                     /tool="antismash"
     gene            17560..>18129
                     /locus_tag="K9S39_RS27730"
                     /old_locus_tag="K9S39_27865"
                     /pseudo=""
     CDS             17560..>18129
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018091255.1"
                     /locus_tag="K9S39_RS27730"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /old_locus_tag="K9S39_27865"
                     /product="CGNR zinc finger domain-containing protein"
                     /pseudo=""
                     /transl_table=11
                     /translation="MAAPHDLRFDCGRICLDLLATGGTPAERLADPQHLTAWLVGAGVV
                     PYGAPLDGVDGGWVTRFRALRDLLRRVVHDELRGRAADADLTQLNATAEAGRPPAVRAV
                     RAADGTLTCAFAGTPDCAGLLAAVARDAVGLLTDPEARGQLRQCEGESCSRVYLDTSRG
                     RRRRWCSSEVCGNRERVARHRRRTMGR"
     misc_feature    18443..18456
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 14.52"
                     /tool="antismash"
     gene            18559..19098
                     /locus_tag="K9S39_RS27735"
                     /old_locus_tag="K9S39_27870"
     CDS             18559..19098
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_function="GO:0016987 - sigma factor activity [Evidence
                     IEA]"
                     /GO_process="GO:0006352 - DNA-templated transcription
                     initiation [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1032: RNA
                     polymerase, sigma-24 subunit, ECF subfamily"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003975857.1"
                     /locus_tag="K9S39_RS27735"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="K9S39_27870"
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="WP_406708027.1"
                     /transl_table=11
                     /translation="MRKDAGVADRTTPDEELMRALYDDHAGPLLAFVLRLVAGDRHRAE
                     DVVQETLVRAWRNADQLNRATGSIRPWLVTVARRIVIDGHRSRRARPQEVDATPLETMP
                     AADVIDRALRLMTLSEALGDLSQAHREALVETYFKERTVSEAAAVLRVPAGTVRSRVFY
                     ALRSLRLSLEERGVTE"
     gene            19095..19838
                     /locus_tag="K9S39_RS27740"
                     /old_locus_tag="K9S39_27875"
     CDS             19095..19838
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006605308.1"
                     /locus_tag="K9S39_RS27740"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="K9S39_27875"
                     /product="anti-sigma factor"
                     /protein_id="WP_248866040.1"
                     /transl_table=11
                     /translation="MIPPTQPDRHSDVGAYALGVLDAADTERFEAHLAGCDRCAAALEE
                     LMGLPPLLAEFKESAPTPETVTAAPGRGLLDGLLGEVAAARRARGRRRLSLVAAAAVLI
                     VGGPLAAVALTADRSGDDRPPPLANAVRAQFDQGEKAAAVDPVTKVSAGVSMAPKTWGT
                     QVVLQLANVKGPLTCDLVAVGKDGRRETVTTWAVPEGGYGIKDSDVKWNREPLYATGGA
                     ALNRGDIDRFEIRTLEGKRLATVEV"
     misc_feature    20182..20195
                     /note="TFBS match to CatR, H2O2-responsive repressor,
                     confidence: medium, score: 19.27"
                     /tool="antismash"
     misc_feature    21066..21079
                     /note="TFBS match to ANR, Anaerobic transcriptional
                     regulator, confidence: weak, score: 18.47"
                     /tool="antismash"
ORIGIN
        1 gcaggagaag taggagaagt agggggatca ggaccccggg cccctgccgg gtcgctgccc
       61 tccccggccc ttccgggtgc ttccggtccc ttccgccatt tcggcaggcg taaacaggag
      121 acacaggaga caactgcccc ttttgggagg gcggttgttt tttgttgtgg cggttaggtc
      181 acagtcgtac gtccatgtaa cgcccaactc gcgtcaattc ggacatcgag cctttaatcg
      241 accttgacga tgttgggaga actgggaagg gtgggcgcgg catgcgtatg tctggggcgc
      301 gtgcgtgaac ggggagattg agtggcctgc ctcctgtgcg gcgccgtgac tcgggtaccc
      361 cgcgatcggc cagtcgcccc gtacaacgat gctccattga cgagttcagc tactgggggt
      421 agcaggcaca tgacgaagaa gacgcggctg cgcgtagcgc gtatagcggc cggtgcggtg
      481 atcgcggccg gtgcgtcgct caccgctgct ggcgccgcct cggcggccgg tccgggcgac
      541 agcggcccga gccaggatgg cggtttcatc ggcggcatca tcggcgggct catcggcggc
      601 ggcgactccg gcggtgacac gggcggtgac accggtggca cggacggtgg cgtgaccggt
      661 ggtgacaccg gcggcaccga cggtggcgtg accggcggcg actccggcgg cgagatcggc
      721 ggcacggacg gcggcaccga cggtggcgtc atcggcggca cggtcggcgg caccgacggc
      781 ggtgtgaccg gtggtgactc cggtggcacc gatggtggcg tgaccggtgg cgacaccggc
      841 ggcacggacg gtggcgtgtc cggcggcgac tccggtggcg acaccggtgg tgacacgggc
      901 ggcgacaccg gtggccagaa cagcggtggc cagtccggcg gcaacaacgg cggcaacgtc
      961 aacggcggcc agaacagcgg cggccagtcc ggcggcagca ccaccggcgg cgacgacacc
     1021 gccggcacca ccggtggcag cgacaccacc ggcggtgaca gcaccggcac cggcaccgac
     1081 aacgagaaca cccagcccgt cgagcagccg ggccagggca aggagcagat ctccgacacg
     1141 cctggcccgg ccaagcagca ggcgaagggc ggggagctgg ccgagaccgg tgcctccggt
     1201 acgaccttcc tgcttgtcgg cgcggcgacg atgatcgcgg gcggtgtggg cttccgcgtc
     1261 ctgccccgtc tgatcaacaa gaacgccggc ggcgcggctg cggcctgacg ccgatacgcg
     1321 cacacacaaa cgaagggccc gggacgcagt gtcccgggcc cttcggggtt cctgggggcc
     1381 gaccaccggt ttcacgggcc tcaacggccg cgcaccggtc tcagacgact tggtggagca
     1441 gcacaccgac cgcgaccagc gcgatcagca gtgccaccag catcacgggg ttgagctggg
     1501 tgaagaaccc gcccacctgg tgctgaagct gtgccctgct ggcccggcac acggggcagc
     1561 ggccctcgct cacaggggcc gcgcagttgg cgcacaccaa tcggtcgtac gtcatgccga
     1621 cctccttctt cactgcgcca acgcaccgga aggcgcattg gttccctctc ccactgtgcc
     1681 aggtccgcgg cggaacggcg cgtcccccgg aatcccgccc ggaatcccgc ccggattcca
     1741 ccccggatcc ccacggaacc cgaacggaaa tgtgctcctt ttgtctggta gatgccatga
     1801 agaatcgcac caaccaccgg ccatgactgc accggaacgc gaggttcgcg tagggtcacg
     1861 cacaccgacg ggagccgcaa cccggcaacc cgtgccccta cccaggtcga ccgtggtgca
     1921 tcagtgatcc gattcgacaa cgtctccaag acctacccga agcagactcg ccccgcgctc
     1981 agggacgtct ccctggagat cgagcgcggc gagttcgtct tcctcgtggg ttcctcgggc
     2041 tccggtaagt ccaccttcct gcggctgctc ctgcgcgagg agcgggccag ccatggcgcc
     2101 gtgcacgtac tggggaagga cctcggcaag ctgtccaact ggaaggtgcc gcagatgcgg
     2161 cgccaggtcg gcacggtctt ccaggacttc cggctgctcc ccaacaagac ggtggggcag
     2221 aacgtcgcct tcgcgctcga agtcatcggc aagccgcggg ggcagatccg caagacggtt
     2281 cccgaggtcc tcgaactcgt cggcctcggc ggcaaggagg accgtatgcc gggtgagctc
     2341 tccggtggtg aacagcagcg cgtcgccatc gcgcgggcct tcgtcaaccg cccgatgctg
     2401 ctcatcgcgg acgagcccac cggaaacctc gacccgcaga cctccgtcgg catcatgaag
     2461 ctgctggacc ggatcaaccg gaccggtacg acggtggtca tggccaccca cgaccagcag
     2521 atcgtcgacc agatgcgcaa gcgcgtcatg gaactcgaaa agggccggct cgtccgcgac
     2581 cagtcgcgcg gcgtgtacgg ctaccagcac taagcgtgta cggcccccag cactgaaagg
     2641 acgccatgcg cgcccagttc gtcctgtcgg agatcggcgt cggtctccgc cgaaacctca
     2701 cgatgacctt cgccgtcatc gtctccgtcg ccctgtcgct gggcctgttc ggcgcgtcgc
     2761 tgctgatgcg cgaccaggtc agcacgatga agggctattg gtacgacaag gtcaacgtct
     2821 ccattttctt ctgcaacaag aacgacgcgg ccgcgggcac caactgcgac aagggcgcgg
     2881 ccacccagca gcagaaggac gacatcaagg ccgagctgga acggctgccg atcgtgcaga
     2941 agccggtgca gtacgagtcc agcgaccagg cgtacaagca ctacaaggag cagttcggcg
     3001 atacgcccgt cgccggactg gtcacgcccg accagcttcc ggagtccttc cgggtcaagc
     3061 tcaaggaccc gaccaagtac gacgtgatca agtcggcgtt ctccgaacgg cccggtgtgc
     3121 aggaggtgca ggaccaacgg gacaccgttg agccgctctt caacctcctc aacggtatga
     3181 atctcgccgc gctggtggtg atggcgctga tgctcatcgt cgcgctgatg ctgatcgtca
     3241 acaccgtgcg ggtgtcggcg ttcagccgaa ggcgggagac gggaatcatg cggctggtgg
     3301 gggcgtccag cttctacatc cagatgccgt tcatcctgga agccgccatc gcgggcctgc
     3361 tcggcgcact gttcgcgtgt gtgctgctgg tcggcggcaa gtacatcctc gtcaacaact
     3421 ggctggccga taagatccag gtcatcaact tcatcggctg ggattcggtg gccgcggtgc
     3481 tgcccctggt gctgctgatc ggcctgctga tgcccgcgct cgccgccttt ttcgcgttgc
     3541 gcaagtacct caaggtgtga gctttgccaa ggggcgccgt acggtcaact cgccgtacgg
     3601 cgcccttttc tcgcctagac tcaccggcat gtcgggcccg tgttcgtacg accggcctcg
     3661 ccgcatccgc cgcggggcgg ccctgacgtt ggtcttcgcg agcgtgctcg ccaccggcgc
     3721 ggcgaccggc acctggagcg acagcgccga gggcgccgcc ggggcgcggg gccccgggcc
     3781 gaccgccgcc ggactcgccc ccaccgaccg gaccgcggac cgtacggacg tcgagcgggc
     3841 cgcctcccag gccttcgagg acggcaaatc cggctcgaag gccgccgacg aggtggtcag
     3901 ccgcagcggc gaccgctggt cggcgatcta cacacccggt gagttcgagg acttccagcg
     3961 tcagttggac ggccggtaca tcggtgtcgg cctctggctg cggcaggcgg ccggtggccg
     4021 gatagtggtg tccagggtcc agccggacag ccccgccgct cgggccggga tcgccgtcgg
     4081 cgaccggctg cgcgccgtcg acggccgggc ctcccagggg cgtccggtca ccgaggtcgt
     4141 cggtcggctg cgcggcgacg cgaagggccc gcacggcccg tccgccgcgg ccggcacccc
     4201 cgtcgagctg gacctccagc gcggcgaccg ccgctggcgc accaccctgt accgcacccg
     4261 cctcagaacc cagaacgtca ccaccgcccg cccggccggc gccgacggcc cgacccgcat
     4321 caagatcacg gcgtttgcga agggcaccgg ggaggaggtg cgcagggcgg tacgcggcgc
     4381 ctccccgcac ggcgggctgc tccttgatct gcggggcaac accggcgggc tggtcaccga
     4441 ggccgtcgcc tccgccgccg ccttcctgga cggcggcctc gtcgccacgt acgacgtccg
     4501 cggcagccag cgcgcgctgt acgccgagcc tcccggaaat ccccggatcc ccctggtcgt
     4561 gctggtggac ggcggcacga tgagcgcggg tgagctgctg gccggcgccc tccaggaccg
     4621 cggccgggcg gtcgtcgtcg gctcgccgac cttcggcaag ggctcggtgc agatgccccg
     4681 cgagctgccg gacggctcgg tcgccgaggt gaccgtcggc cattaccgca ccccgtccgg
     4741 ccgggccgtc gacggccggg gcatcacccc cgacctgatc gtcggggacg gggcggagaa
     4801 acgggcccgc acagtattga gtggcctcgg caccggtgcg tagtgcgaaa atggcgacac
     4861 gatgactaag cagaccaagg acacaggcaa gggcaaggac aagacccccg ggcgtcggct
     4921 gatcgcacag cacaagaagg ctcggcacga ctaccacatt ctggacacct atgagtgtgg
     4981 cctggtactg accggcaccg aagtgaagtc gctgcggcag gggcgggcgt cgctggtcga
     5041 cggattcatc cagatcgacc gtggcgaggc atggctgcac aacgtgcaca tccccgaata
     5101 cgcgcagggc acgtggacca accacagcgc ccgacggaag cggaagctgc tgatgcaccg
     5161 cgtggagatc gacaagctgg actccaagag ccaggagacc ggccacacga tcgtgccgct
     5221 gtcgctctat ttcaaggacg gacgggccaa ggtcgagatc gcgctggcca ggggcaagaa
     5281 ggagtacgac aagcggcaga cgctgcggga gaagcaggac cggcgcgagg cggagcgggc
     5341 gatctcggcg gcgcggcggc gtcagcgggc ctgacagggc tttccgacgg ggcttcccgg
     5401 ctaccgtcgg ggaatacgct ggcaccgtcg tgcgttgttc acgtacgatg gcggcgcacc
     5461 ccaggagggt gtgcgacacc ttggggtgaa ctgggcgacc ggcttacctc aggggtgctt
     5521 gataaaaaaa catggggatg atcggtttcg acagcggatg tcgaagcagg ggaagcgagt
     5581 cgaggaagcg gcaatgatct cgttaaccat atgtcgcaac caataatcgc caacaccaag
     5641 cgcgattcct tcgccctcgc tgcctaagta gcgacttgcg aagtgtcagc ccggggctgt
     5701 tcccgacccg gatcctggca tcagctaggg aactaaactt ctagacccgg tcacggggtg
     5761 tagaaggaaa tcaaacagtg actgagcccg tcggagactt gtccgcgtga tctccggggc
     5821 cgagaaaagc gcagcggact gcactcggag aagccctgat tccgcaccgt tggacgcggg
     5881 ttcgattccc gccatctcca cttcgtcgac aggcgacgtg tgcccgcgaa tagcgcgggc
     5941 acacgtcgcc ttcgtcgtat ctgcacgggc tgcgcccgcg tgatgcgggg ttctgccacc
     6001 cgcatcccct gtaccggggc gggccggggg caactcagcg tgcacgggac ctgagccctt
     6061 tccgccgact catggtgacg gccagggcga gggcggcggc cgtcgcaggc atgacgtacg
     6121 ccggcccggg gcccgccaga tggtccaccg cccagccgcc cgccgccgaa ccggccgcga
     6181 taccggccag cagggcggtg acggccaggg tcatcccctc gttcaactgg gccgccgggg
     6241 tgcgggattg gagcagcccc atcccggtga ccatggtcgg cgcggtggcc atccccgcca
     6301 ggaggagagc gacggccagg gccggcagac tccccgttga ggcggcggcg aggggcagcg
     6361 gcatcagggc ggacatggcg gccacacagc ccaggaagcg gctgcccgcc gggcccgtcg
     6421 gccgcagcag cccgtagagc aggcccgccg cacaggaacc ggccgcctgg agcgcgagca
     6481 tcccgccggc cgcgggccgt acgccgtgga cgtccgcgaa ggcgatcgtc acgacctcca
     6541 gggagccgaa gaccgcgccg gtggcgagga aggtgaggag gaggggcgac aggcccggaa
     6601 ggcggagcgg agagcgcgga cgccccgtcg tcctgggggc gacgggcggc tcggtaccgc
     6661 gctgcgccgc gaagagcagt actcccgtca acagcagggc ggccgcgacc gccgtacccg
     6721 cctccggcaa gaaggcggtg cagagcagtg tcgccagcac cggaccgagc atgaagcaga
     6781 gctcgtccgc cgcctgctcg aaggaattcg cggtgtgccg ggcggcgggg tcgccccgga
     6841 agaggtgggc ccagcgcgcg cgtgacattc cgccggtgtt cggggtggtg gcggtggcga
     6901 tgtacgaagc gaagagggcc caggcgggcg cgtcgtaatg gacgcacagg aggagggaga
     6961 gggagccgag ggcggcgatg acggtggccg ggacggcgat ccgggactgg ccgtatcggt
     7021 cgatgaggcg cgcggtcagc ggcccgacca gcgccgttgc cgtcagcccc gtcgcgacga
     7081 cggcaccggc cagcgcatac gagccgcgcg tcccggcgat catcaggacc gcgctgacac
     7141 tgagcatgcc catcggcagc cgggccagca gattggcggc ggtgaacgcg cgggtcccgg
     7201 ggacggcgaa aatccggcgg tagggggcgg tgagggtgac ccctcgtcca tggcgacgta
     7261 cgcgggggga cggccgtacg ggcggggacg gtggtacggg cggggcggtg acgggacgcg
     7321 ggacgacgga acgcggggcg acggggcgca ggacggcggg gcgcgggacg acgggacggg
     7381 cgccgaggaa gaggatcatg ccttctaccg tcgcggcagc cctcgtcgcc cgtccaacac
     7441 ctgatcagca cccattcacg cacccgtgtt gtcaatgggg cctgccgcct tccgcctgcc
     7501 gcgaatgcca ggatggcccg gtgccgtacg acatagcccc ccggctgctg cgcgccttca
     7561 ccgccgtcgc cgacgagctc cacttcaccc gcgccgccgc ccggctgtac gtggcccagc
     7621 aggcgttgag ccgcgacatc cggcggctgg agcgcgagtt gggcgccgac ttgttcgtac
     7681 ggaccacgcg ccaggtcgcc ctcacggcgc acggggcacg tctggtccct tacgcacggc
     7741 gggtgttggc ggcccacgac gagttggccg ccgcgttccg cgccacgccc gagcgcccgc
     7801 tgctggtcga tgtcggggtg ccgatcggta cggcccaccg ggtgctggag gaggcccggc
     7861 gccgggtgcc cgacagctgc gagctggtcg cccgcttcca cagcgggctc acgggtgcgg
     7921 cggaagagct gcgggccgta cggctggacg tctccttcgg ccgcttcgcc gcactgccac
     7981 ccgccgtacg ggccggcctc gaccatcagc cggtccgtct ggagccgatg gcggtgctgc
     8041 tccccgagga acaccggctg gccgcacggc ccaccgtccc actcgcggaa ctgaccggtg
     8101 agaccctgta cgccgccgcc gggaacccgc aggccgtcga gtggacggac ctggcggcgc
     8161 gcctcttcga ggggcggggg atcgcgatgg ccgcaccgtt cccggagatc gagggttcgc
     8221 aggaattcac gcgggtggtg cgcaagcagg ggtgggcggt gctggcgagc gtggagttca
     8281 tcgacgtgcc ggggatggtg ctgcggccgg tggtcgatcc cgtacccctg tcgccggtgg
     8341 ggatggtgtg gcggcgcggg ctgaggcatc cggggctgga cgcgctgcgg gcggccgcgc
     8401 gggaactcgg cgaacgggac gcgtggttgg cgcctcccgg ggacggctgg tggctcccgg
     8461 aggcggacgc cacggcgatg ggcctgcgct gatccgtacg cgatagctgg gggacgactg
     8521 cggacgaccg cggatgtccg ggatgaaggc gggcgaatac gggcggttat ggacgactgc
     8581 ggatgactac ggacgcggag gcaaccccgg gcacgcgaaa tccttcctta acggcgggaa
     8641 actttatgcg gaacgaacag ggacaggggg agccgtgcgg cggcgctcac ttctcgcggc
     8701 gacggcggcc gcgctcattt tgaccgtctt cggcctgggg ctggtcggct gcggctcacc
     8761 gcggatggcg gccctgcacg ccgactgcac gaccaaagac ctgaagtgga agctcgccgt
     8821 cctgaagaag aagccgcaca gcacacatcg tgaggcccgg ctcaccgccg tcaacgaggg
     8881 cccgggagcg tgtgtcttcc gcggtttccc ggtcttcgag gtccatgtcg gcaagggccc
     8941 ggagtcggac gggaaggggc gcggccagac catgccgatc gacctgcggc gcggcggcac
     9001 ggtgacgacc agcctgcgct acaaggactc cgaccggggt acgccgtccg ccgcctgcat
     9061 ggtcagcaat gacacggccg tggtcgccgc accgcgcgac accacgggcg gccgggcgat
     9121 agcggcccgg gacgagacgg gcggacgggc tcggatgacc atctgcgagg acacggtctg
     9181 gatgagcccg cccaaggaaa tcgccgagta gccccggttg ttacggggcc gccgttgccg
     9241 cgaaggcggc gaacgacgcc gcgttgatgg tcgggggttt ccagcagcac gaacgggccg
     9301 tcgagcctgg cgtgagtcgg gcagttcaga ggcaggatct gaatctggac gccggggagc
     9361 tccgcgcatg tgcgcaggtg ggagttctgg ccgcattacc tcgggtccac cgagcccgcc
     9421 caacaggatg gctctgcgat gacgaaactg gcgctgacag gtttcggctt gtgcacgatc
     9481 tgctgacggt cctgccgggt tgtgacgcgc tgctcgatct cctcttcggt gaggtgcggg
     9541 ataacgccgc tgcgcaaggt ggcccgtgcg tagtccgagg tctggagcag accggggatg
     9601 accacgttct cgtaccagca aagcgcgatg gcctcccgct cgaaatccat gaactcctcg
     9661 gcccacaccg ggaacttctc ccgcttcggc agcttctcca cacccacctt gagcgcgccg
     9721 cctgtcttca gaatccggtc gatctccact gccgggcgcg gcaacaacgc ccgcctcccc
     9781 tgctcgatga aggcgatggt ctgctcggac acgctcacga gattgccgag ttcgcgttgg
     9841 gtgaggccgg cgttcgcgcg gaacagcgcc atgatcgcgc cgaggacttc catgttcgag
     9901 gactgcctgt ttctttggct tcatgccgac ccgctcccct gtgacgccct tcgtgaccgc
     9961 gcgtgcaccc gtactctccg tgggtacggg tcggcctgga tcagcgcggg atggacagca
    10021 gcggctggta aaggcgggtg tcgtcgggtt cgccgatcgg gtggccgtcg acggcgaccc
    10081 aggcgcgggc gcggaacggc tccgtgcgca cccccgtgca ccactggggc cagcggccgc
    10141 gcgtacggca caacagggcg gtggcgaggg agcgttggag gcagccctgg cccgtgcagc
    10201 gggcgttgac cgtgacgacg gcgtgccggg cccgtagcgc gtcgggcgcg gtggcggggc
    10261 gggcgccgcg gcgtacgcgg tccaggacgc ggcagatggt gcgcggggag cggcgcgcca
    10321 ggagccgcgc tgcggcgacg cagcagcggg cggtgcagcg ttcggtgagg gtgaggtgtg
    10381 cgcgcgggtc gatggagagg gggacgctca agaggtcacc agcttcgcgg acttgaggga
    10441 ggagagcagg gcctttgtgt ccgcttcgac gcggtcggcg gcctcggggt ggcggatgcg
    10501 cagttcggcg acggctgatg tgcaactccc gccggccaaa aggtgttcaa gaatcagagc
    10561 gccggtttcg ttgagttgcc agtagcggcc cgttcgggtg ttgaggagga tcatgccgcc
    10621 gggggtgcgg gtgctggtga tgtcgggggc gagggagacg gagaggggca tcaggctcct
    10681 tcggcgggag atgcgggggc atgcgggaga tacgggatgc gggaggtaag ggggcagcag
    10741 tcgcagctac ggggcggccg tggcggttgc ggaggcagga gtgacagcgg ccgggggcgg
    10801 gagttggccg tacgggaggg agcgcagcca gtattcggcg gcgagtgtgg ggtcgagggg
    10861 gagcagggtg tgggtgtgcg gatggaggga ggtgaggacg tgacgtaggg cgtcggggcg
    10921 gatcaggccc aggcgggcca ggagtgagtc gtcgcagagg gcggagagtg cgcgacggtg
    10981 gcggcgtagg cccgcgtaga cctcggcgct gtggtcgcct ttggtgccgc ggccgagcac
    11041 ggcgtcgggg acgaggccgc gcatggcggt ggcgagcagg ggcttgtatg cgccggtctc
    11101 ggtgtggccg gcgagacgga cggtgagtgc cgccttgatg acggcgtcgt cgagaaaggg
    11161 ggcttcgtag gcgacacctt gggccgaggc caccgcgtcg atgccgcgga cgatctctcc
    11221 ggcgcgtacg gcggcgcgta cggtctcgtg ctgagcgcgc agcgccgcgt acggctcggg
    11281 cgcttcggcg gccgcttcgc gcagcaggcg gcggacggtg gtgaccgcgt ccgggtgtgc
    11341 ccagggcggc atgctggggg cgatctccca ggcggcgccg gtggtgccgt gctgctcggt
    11401 gcaggtggcc agccactggg ggtacgagtc gccgttccag agggtgtgca ggctgtcccg
    11461 gagggggcgc agggggtcgg ggagtgtcca gcggccgagg cgccgggccc tgaggggctg
    11521 gcgggcggtg cggaggtcgc ggcgggcgag tgagtgcagc gccaccgggc gagggttcag
    11581 tgccgccggg cgggggtcaa gtgccaccgg gcgggggctg aagagttcgt cgccgccgac
    11641 accgaccaga tgcagccggg agccgcgttc ggcgacgagg cgggcgtggt gggagagccg
    11701 ggcactctcc ctgatcgcgg cgagcgggcc ggccgggtcg gtgtggccgg ggtcggaggg
    11761 cggggtgtac caggtgggca cctcggcgta aggaagggag agatgttcgc cgacgttgcc
    11821 gccgccggtg tggtcgccgg tgctgaggtg ggccgcgctg cgggcgctcc agaggttgtc
    11881 gtcgttggcc ggatcgcggc actgccatgc ggtggtgatc aggcgagtgt gcggggcgcg
    11941 ggcggccagg aagcacaggc tggtggagtc catgcctccg gagaggtcgg cgctgagcgt
    12001 cccgtggcgc gtacggaccc ggacggccgc gctgagggcg tcccgtacgg cctcggcggc
    12061 gtccggcagg ggcgtgtccg gtgcgggcgg ctgccaccaa cgccgcacga cgtggcggcc
    12121 gttgggggcg aaggtgaggt agtggcccgg tggtacggcg tggaccgacc gccaggcctg
    12181 gcgcagggcg agggggagcg gggcaaaggg ggtgagcaga cgggcggcca gggtctcttc
    12241 gtcgacggtt ccgaggtggg gtgcgcggtc caggccggtt ttcgcggcct cgcaccccag
    12301 ggcggccaga ttctgggggc ggttgccggc gacggcgatg ccgccgatgt ccgtgtgatg
    12361 tagctgacgg tacgtcgaaa gacttccctg gcagcggact tcgggaccga aggccgccat
    12421 gagaaagaag ctgccgggca ggtcgcctag gtgtgcgcgg aggtggtcgc cgaggtcgtc
    12481 gaggctggtc aggcggcgga gcaggcgggt cagcccgtcc cgggtggcgg aggtggtacc
    12541 gagcagtgcg atgcggcgcg ggccgatccg tgccgtgatg gtctcgtcgc ggctccagtg
    12601 cccgacgatc caggggcggc cggaggcgta cggcacgatg cggagggttg gcctccggtg
    12661 caggcaggcg atgagccggt cggcggcggg atggtcgggc aggacgagga aatccacggc
    12721 gcggtaccgc tccttgggcg cattccttgg gtgctggggg tgtgggcccg gaggtcctgc
    12781 cggggcgggg aggcgcctcc cggcaggacc ggttcaggac cggttacgga cggccggtcg
    12841 ctactcctgc cagaagtgcc cgccgaaggc atcgtgatgc cagccgacga gtcccggtgt
    12901 cagctcggcg aagtcgccca catcggccag ttccggcacc tcgtactcga cctgctctac
    12961 gtccccgccg cactcggcat gctcgacgtc cccgccgcac tcggcctgct cgacctgctc
    13021 ggtgtaaccg gcgtgctcgc cgtacccgac gtgcccgccg tacccggcgt gctcccgcgg
    13081 ctgctgaagc tcctgcagca gttcctgcat gagatcctgc atgagtcgca cttccttccc
    13141 tggggtgctg cacaaccgcg ccgaggacag cggaaagtgt cggcgtgact acgttctgct
    13201 tccgacgcaa aggctggcag cagccgcagc ccgttccatt accccgaacg ggtgaacgcg
    13261 ggggcgcgcg aggcgtggcg gcgcggagcc tgctcaccgc acgccgtcgg gccccgtgag
    13321 agcaaggttt cgcggcggtc acttcccgcc acgggccgga aacgcgccgt ccctagcttc
    13381 gagggagatg gctggatccc cctgggaggc gcgatgacaa ccgaggcagc acgtaccggc
    13441 ggcagtagtg gcaggcgagg agggcactgg atcgagcact gggatccgga gaacgagaca
    13501 ttctgggcgg agtcgggcga gcggatcgca cggcggaatc tgtggttctc cgtgatgtcc
    13561 gagcacatcg ggttctccgt gtggagcctg tggtcggtga tggtgctgtt catggggccg
    13621 gagtacgggc tggccccggc cgacaaattc ttcctggtcg cggtgacgac actggtgggc
    13681 gccgtgctgc gggtgccgta caccttcgcc gtggcgaagt tcggcgggcg caactggacc
    13741 atcatcagcg cgctgatgct gctcgtgccc accaccgccg cgtggttcgt gatggaaccc
    13801 ggcacctcat acgggacctt cctgctgatc gcgtcgctca ccggtatcgg aggcgccaac
    13861 ttcgcctcgt cgatgaccaa catcaactcc ttctatccgc tgcggaagaa gggctgggcg
    13921 ctgggcatga acgccggcgg cggcaacatc ggcgtaccgg tcatccagct ggtcggcctg
    13981 ctggtcatcg gtaccgcggg cgccgcgcat ccgcacatcg tgctgggtat ctacattccg
    14041 ctggtcgtcg tctcggcggt gtgcgccgcg ctgttcatgg acaatctcgc cccggtgaag
    14101 aacgacaccg gcgcggccaa ggacgccgcc cgtgaaccgc acacgtggat catgtcgctg
    14161 ctgtacgtcg gcaccttcgg gtccttcatc ggctacagct tcgccttcgg cctggtcctg
    14221 acgacccagt tcgaccgcac gccgctgcag gccgcttccc tgaccttcat cggcccgctg
    14281 ctgggctccc tggtccggcc ggtcggcggg cagctggccg accgcttcgg cggggcgcgc
    14341 atcaccctgt ggaacttcgc cgcgatgggc gccgcgaccc tcgtcgtgat cttcgccgct
    14401 gtgcaggagt cgctgccgct cttcctggtc ggctttatcg ccctcttcgt gctgaccggt
    14461 gtgggcaacg gctcgacgta caagatgatc ccgggcatct tccagaacaa ggcgctggag
    14521 cgcggactca ccggcgaggc cgccgcggcc tacggccgtc ggctctccgg cgcctcgatg
    14581 ggcctcatcg gcgcggccgg tgcggtcggc ggcctgggca tcaacctcgc cttccggcag
    14641 gcgttcatga cgacgggttc cgggaccccg gccttcgtct ccttcctggc cttctacgcc
    14701 ctgtgcctgg tcgtgacctg ggccgtatac ctgcggcggc cggcgggcgc acggtccgcg
    14761 gcggagccgg gaaccggcga ggcggacgag gaggccccgc ggcccgtgta cgccgaggtc
    14821 tgaggcgcgc ttccgtaaca cgggagcggg tttccgtaac agtggggaaa tgtcgaggga
    14881 ccgtgtctgt cacgtgctgt tggcaggctc ggctccttca tcaggccttg tccgggggct
    14941 tggcagtcgt gccggacggg cgcggcgggc tccgacccga cgtgctccat ggggccggac
    15001 agggccgccc gtaccagccg gagccgcggc gttacgggag cacgaaatgc accacaccac
    15061 tctgggcgga gcgggacgac catgcaccaa caccagcagg ttcaaaagga gcgggatcac
    15121 agggagcagc agccggcgac gccggcgccg ggcgtacggc cgctcgacgg gttcactgtc
    15181 ggggtgaccg cggcccggcg ggcggaggag ctgggcacac tgctggagcg gcggggcgcg
    15241 caggtgctgc acgcgccggc actgcgcatc gtgccgctgc cggacgatga cgggctgctc
    15301 gcggtgacca gatcgctgat cgaggacgcg ccggacatcg tcgtggcgac caccgccatc
    15361 gggttccgcg ggtggatcga ggccgccgag gggtgggggc tgggcgagga cctgctcgac
    15421 cggctggccg gggtggagct gctggcgcgc ggcccgaagg tgcggggggc gatcagggcc
    15481 gccgggctga ccgagaagtg gtcgccggcc tcggaatcga tggcggaggt gctggaccgg
    15541 ctgctggcgg agggcgtctc cgggcgccgg gtcgccgttc agctgcacgg ggagccgctg
    15601 cccggtttcg tcgaggcgct gcgggcggac ggcgcggagg tcgtcggcgt ccccgtctac
    15661 cgctggatgc cgccggagga catcgggccg gtggaccggc tgctggacgc ggtgctcggc
    15721 cgcggggtgg acgcggtgac gttcaccagc gccccggccg cagcgtcgct gctgcggcgc
    15781 gcggaggagc gcggcatacg ggacgaggtg ctggcggcgc tgcggcggga ggtgctgccg
    15841 gtgtgcgtgg ggccggtgac cgcgctgccg ctgcaggcgc acgacatccc caccctccag
    15901 ccggagcgct tccggctggg gccgctggta cagctgctgt gccgtgaact cccgggccgt
    15961 gtacgaccgt tgccggtcgc cgggcggtgg ctggaggtcc gcgggcacgc ggtcgtggtg
    16021 ggcggagagc tgcggccggt accgccggcc ggcatggcgc tgctgcgcgc gctggcccgc
    16081 cgccccggct gggtggtctc ccgcgcggat ctgctgcggg cgctgccggg ggcggggcgg
    16141 gacgagcatg cggtggagac ggcgatggcc cggctgcggg tggcgctggg cgcgccgaag
    16201 ctgatccaga cggtcgtcaa gcgggggtac cggctgtcgc tggacccgca tgcggacacc
    16261 gacaagtacg ggggagcgtg agttgtaggg gcccggccgg aggtccgccg ctcttccggt
    16321 cgcttccggg gcgcctcgcc ccgggggctg cctcctctca cgccacgtcc cctcctcgcc
    16381 ccggcttgtt ccctccctca ctccggattg tcgactcgga cctcgccccg gcttggattc
    16441 gactcgggcc tcactccgga ttgttgacgc ggatcttgga ctggccgtgc gggcgcttct
    16501 cccagtcgtc catgaagcgg gcctccaggc cgtgtttgcg ggccaggttc agcagcgtct
    16561 cggtgcggta gtagaagtcc tcgcgcagca cctggtgttc ggtgccctcg gtgcggtcga
    16621 aggtgaagtc gaagaagccg ccgggagcca ggacgcggcc gacgtgtgcg agacattcgt
    16681 cgatgacggg gagcggtgag tgcgagaaga cgctgtgcgc gtggacgacg tcgaagtggg
    16741 cggccgggag gaagtccagc ttcagatccc tcgtgatggt caagtgcggg agtttgtgct
    16801 ggagttcgta ggtcgtcagg gtcttcttgg cggatatcag gatgtccggt gagatgtcga
    16861 cgccgtagta gttgcccgtg tccaggtggg cgatgaagcg ccagccggcc cgcagattgc
    16921 cgcagccgat gtcgagcatc cggtggccgg gcttcaggcc gtgctccgcg agataggcga
    16981 actgcatctc gcccagggcc agccagcgtt catggctgcg gctgccgacc gcggcctccg
    17041 ggttgcggtc ggtgtcggag gccatcaccg cgcggtagta gtcgacgtgg tcggggtgtt
    17101 tgaggcgcag ccaggtgtcc cgtgcggtgc gtttcacgta cggggtgatg cgggccgggt
    17161 tgcggaccgc gtagccgatc ttgtgggtca ggctggcgcg gtttttgagc agcgatttgg
    17221 gcgacatggt gaccttcgtc ctggaggggg cggaaggggt ggggcggaag gggcaagggg
    17281 tggtggccgc cgggggcggt ccccacgtcg ggactatacg ttaaatgtat acgcgagttg
    17341 tgtacttggg gtgtctacct gcgtgccggg atcgcgcccg ggattttgac ctccgtgtcc
    17401 ggggcttctg cctccggtgt ccggggtgtc tgccttccgt gcccggaggc gtccgcctcc
    17461 ggtgtccacg ccgggcgcgt gccacggagg gttccggccg gcttgcgcgc cgggcactct
    17521 gggggcacac gcgtttgttc gctaaggagt gacaggcaca tggcggcgcc tcacgacctg
    17581 cggttcgact gcgggcggat ctgcctggat ctgctggcca ccggcggcac ccctgccgaa
    17641 cggctcgccg acccgcagca cttgacggcc tggctggtcg gcgcgggggt ggtgccgtac
    17701 ggcgccccgc tggacggtgt cgacggcggt tgggtcaccc gcttccgggc gctgcgcgac
    17761 ctgctgcgcc gtgtggtgca cgacgagcta cggggccggg cggccgacgc cgacctgacg
    17821 cagctcaacg ctaccgccga ggccggccgg ccgcccgccg tgcgggccgt tcgggcggcc
    17881 gacggcactc tgacctgtgc tttcgccggg acgccggact gcgccggact gctggccgcg
    17941 gtggcgcggg acgccgtggg actgctcacc gacccggagg cgcgcggcca gctgcggcag
    18001 tgcgagggcg agagctgctc ccgggtctac ctggacacct cccgcggccg gcgccgccgc
    18061 tggtgctcca gcgaagtgtg cggcaaccgg gagcgggtgg cgcggcaccg gcggcggacg
    18121 atggggcggg acgcggcgga agcgcccccg gccggcccgg ccgccccgaa catcccggcc
    18181 gccccgacgg tctcccgcgc acccgtttcc ccatccaccg ccccgcccgc ttccccaccc
    18241 acctcaccta cttctgccac ctccccacac acttcccagt ccaattcacc cacttcctcc
    18301 cccacctccc agcgcgccgc gaaaatttcc ggcggaccgt gaacgcaccg cccgtcccgt
    18361 ccgtactcct catcgcacgg acccgcggcg gtgcccccgg ctgccgcccc gacagtcgcc
    18421 gccgcggatc cgtacaagtc cgattcataa caacaagccc gatccgtggc aaagagcacg
    18481 attcatggca acgagtccga tccgtggcat gatcccggcg ctgttccggt gatccgcgct
    18541 atcgacccgg gagttggagt gcgcaaggat gccggcgtgg cagacaggac gacacctgac
    18601 gaggagctca tgcgagccct ctacgacgac cacgcgggcc cgctcctcgc cttcgtcctg
    18661 cggctggtgg cgggcgaccg gcaccgtgcg gaggacgtgg tgcaggaaac gctggtgcgt
    18721 gcctggcgca acgccgacca gctgaaccgc gcgaccggct cgatccggcc atggctggtg
    18781 accgtcgccc gacggatcgt catcgacggc caccgcagcc gccgggcccg gccccaagag
    18841 gtcgacgcga cgcccctgga gacgatgccc gccgccgatg tgatcgaccg ggcgctgcgc
    18901 ctgatgacgc tttccgaggc gctgggcgac ctgagccagg cccaccggga ggccctcgtc
    18961 gagacgtact tcaaggagcg tacggtcagc gaggcagcgg cggtgctgcg cgtaccggcc
    19021 gggaccgtgc ggtcccgcgt cttctacgcg ctgcgctccc tgaggctctc ccttgaggaa
    19081 cgaggagtga cggagtgatc ccgcccacgc agccggaccg gcacagcgac gtcggcgcct
    19141 atgcgctggg cgtcctggac gccgccgaca ccgaacggtt cgaggcgcat ctcgccgggt
    19201 gcgaccggtg cgccgccgca ctcgaagagc tgatgggcct gccgccgctg ctcgccgagt
    19261 tcaaggagtc cgcgccgacg ccggagaccg tgaccgccgc ccccgggcgc ggtctcctgg
    19321 acgggctgct cggcgaggtc gccgccgccc gccgcgcccg cggccgccgt cggctgtctc
    19381 tggtggccgc tgccgccgta ctgatcgtcg gcgggccgct cgccgcggtc gccctgacgg
    19441 cggaccggtc cggggacgac cgcccgccgc cgctcgcgaa cgccgtccgc gcccagttcg
    19501 accaggggga gaaggcggcg gccgtcgacc ccgtcaccaa ggtctcggcg ggcgtctcca
    19561 tggcgcccaa gacctggggc acccaggtcg tgctccagct cgccaacgtc aagggtccgc
    19621 tcacctgcga tctggtcgcc gtcggcaagg acggccggcg ggagacggtc accacctggg
    19681 cggtccccga gggcggctac ggcatcaagg acagcgacgt gaagtggaac cgggagccgc
    19741 tgtacgccac gggcggggcg gccctcaacc gcggcgatat cgaccgcttc gagatccgca
    19801 cgctggaggg caagcggctg gccaccgtgg aggtgtgagg cgggggcgcc ggaggccggg
    19861 agcgccgggc gggtgatgtc cccctacgtc accctcgtac cgcccccata ccgcccctga
    19921 tgccacccgt tgtcatgacc ttggtcagtt gtgacagatg accggtcaag gacggagtca
    19981 cgtccccgtc aacatccgac cggacacgtc cggttttgtg tatttggcca ggtgcgcgcg
    20041 gtggctggtt cgcgtacggt tgacggctgc cctacgcaca gcagaagggg gcctgggtgg
    20101 ccgcgcagaa cgccacgcac gcaccggatc acgcttcgga ttccgttcgc gaccgcgaga
    20161 tcgaggccga gcagacgcac ctggaccgcg tctaccggcg ccttgaggag aagatccacg
    20221 aggcggagtt cctgatggac gacgccgcca agcgcggcca ggtcggcaca cccggcgcgc
    20281 tcgccgagcg cgacgcgcag gtcttccagg ccggcgtcca tctccaccgc ctgaactccg
    20341 agtacgagga cttcctcttc ggccggatcg acctgctcct cggcaaggac ggcaagaagg
    20401 gcccggacgg cgcctacacc tccgtcgagc ccgccgacgg cgcgatcgag gacaaccgcg
    20461 ccgagatcgc cgagacgctg cacatcggcc gcctcggagt cctcgacgcg gactacgcgc
    20521 cgctggtcat cgactggcgc gcgccggccg ccgcgccctt ctaccgcgcc accccggtcg
    20581 cccccggccg ggtcgtccgc cgtcgcgtca tccgctccaa gggccgcaag gtcctcggcg
    20641 tcgaggacga tctgatgcgc ccggaggtca ccgccacgct ggacggcgcg gagctgccgg
    20701 cgatcggcga cggcgcgctg atggccgcgc tgggccgggc ccgcagccac accatgcgcg
    20761 acatcgtggc ctccatccag gccgagcagg acatggtgat ccgggccccc gccgcctccg
    20821 tgaccgaggt cgagggcggc cccggcaccg gcaagaccgc cgtcgcgctg caccgcgccg
    20881 cctacctcct ctaccaggac cgccgtcgct acgcgggcgg catcctcgtg gtctccccga
    20941 cgccgctgct ggtcgcgtac accgagggcg tgctgccgtc gctcggcgag gaggggcagg
    21001 tcgccatccg tgccctgggc tcgctggtgg acggcgccga ggcgaccgct tacgacccgc
    21061 ccgaggtggc ccggatcaag ggctccagcc ggatgcagaa gctgctgcgc aaggcggctc
    21121 gcggggcgct ggaactggcg gccccggacg cggccgggcc ggcgcgggaa gccgggccgg
    21181 gcaccggcca ggacgcccag ctctccctgg aggacctcat cacggcggcc ggggacggca
    21241 ccggcgactg caccgggggc gacgcggccg acaacggtgc caagaacggc gtcacgaacg
    21301 gtgccaagaa cggcgtcacg aacagcgcca agaacggtgg ccagggccgc cgggcccgct
    21361 ccgggacccc acgtcccacg atgcccaccc cacccacccc acccacccca cccgccgcgg
    21421 gcccgccgac ccgcctccgc gtcgtcgcgt tcggcggccg tatcgagctg gacgccgacg
    21481 agctgcaccg cgtccggcag gccgcgctcg gcgggaccgc gccggtcaac ctgctgcgcc
    21541 cgcgcgcccg ccggctgctc ctcgacgccc tgtggaacaa gtcgggcgcc ggccgccgct
    21601 acaccgaccc cgagctggcc gccgaggccc gccagggctt cgacgaggac atcaccaccg
    21661 agccggagtt cctggagttc ctggacgcct ggtggccgga gctcaccccg cgcggagtgc
    21721 tggccgcgat ggccgacgag cgcctgctgg gccgctgggc ccggcgcatc ctcaaccccc
    21781 gcgaggtgcg ccaactggcc cgctcgctgc ggcggttgga cgaggggggc acctcccatg
    21841 ccgttaaggc gatgggggac gggcacggcc cgctgtcggt gcacgatgtc gcgctgctgg
    21901 acgaactgca gctgatcctc ggtgccccga tgcggccggc gaagccgcgc gaggtcgatc
    21961 cgctggacca actcaccggt ctggaggagc tgtcgacctt cgcggaccgc acctccgccg
    22021 gccgcggccg gcgcgagcgg ctggccgagg aacgcaccga ctacgcccat gtcatcgtcg
    22081 acgaggcaca ggatctgacg ccgatgcagt ggcggatggt cggccgccgc ggccggcacg
    22141 ccacctggac cgtcgtcggc gacccggcgc agtcctcgtg gtccgacccg gacgaggccg
    22201 cgctggcccg ggacgaggcg ctcggcgccc gtccgcgccg ccgcttcacg ctcaccgtga
    22261 actaccgcaa ccccgcggag atcgccgagc tggcggccaa ggtgctggcg ctggcgatgc
    22321 ccggtatggc ctcgccgcag gcggtccgct ccacgggcgt cgagccgcgg ttcaccgtcg
    22381 ccgcattgga cggggagcgc gctgccgccg ccgacgaggc gctggcgcgg gccaccgtcg
    22441 acgaggccgg gcggctgctg gacgaggtcg acggcacggt cggcgtcgtc gtggccatga
    22501 agcgccgcga acaggcccgc cgttggctgg ccgggctcgg ggaccgggtg gtggccctgg
    22561 gctccctgga ggccaagggt ctggagtacg acgcgacgct ggtggtctcg ccggccgaga
    22621 tcgccgacga gtccccggcc gggctgcggg tgctctatgt ggcactgacc cgcgccaccc
    22681 agcagctgac ggtgctctcc accgggagcg acgaacc
//
