LOCUS       NZ_CP086322            33046 bp    DNA     linear   CON 26-NOV-2024
DEFINITION  Streptomyces halobius strain 3_2 chromosome, complete genome.
ACCESSION   NZ_CP086322
VERSION     NZ_CP086322.1
KEYWORDS    RefSeq.
SOURCE      Streptomyces halobius
  ORGANISM  Streptomyces halobius
            Bacteria; Bacillati; Actinomycetota; Actinomycetes;
            Kitasatosporales; Streptomycetaceae; Streptomyces.
REFERENCE   1  (bases 1 to 9239126)
  AUTHORS   Wen,Y., Zhang,W. and Liu,X.G.
  TITLE     Streptomyces nigrumlapis sp.nov.,an antimicrobial producing
            actinobacterium isolated from Black Gobi rocks
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 9239126)
  AUTHORS   Zhang,W., Liu,X.G. and Wen,Y.
  TITLE     Direct Submission
  JOURNAL   Submitted (04-OCT-2021) Northwest Institute of Eco-Environment and
            Resources, CAS, Chinese Academy of Sciences, Donggang West Road 320,
            Lanzhou, Gansu 730000, China
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method :: GS De Novo Assembler v. FEB-2021
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 241.26X
            Sequencing Technology             :: PacBio Sequel
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_023277745.1-RS_2024_11_26
            Annotation Date                   :: 11/26/2024 03:43:17
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.9
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 8,438
            CDSs (total)                      :: 8,346
            Genes (coding)                    :: 7,837
            CDSs (with protein)               :: 7,837
            Genes (RNA)                       :: 92
            rRNAs                             :: 6, 6, 6 (5S, 16S, 23S)
            complete rRNAs                    :: 6, 6, 6 (5S, 16S, 23S)
            tRNAs                             :: 71
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 509
            CDSs (without protein)            :: 509
            Pseudo Genes (ambiguous residues) :: 0 of 509
            Pseudo Genes (frameshifted)       :: 193 of 509
            Pseudo Genes (incomplete)         :: 418 of 509
            Pseudo Genes (internal stop)      :: 17 of 509
            Pseudo Genes (multiple problems)  :: 113 of 509
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 18:33:41
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 2314543
            Orig. end                         :: 2347589
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP086322.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            This genome has a base modification file available.
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..33046
                     /candidate_cluster_numbers="1"
                     /candidate_cluster_numbers="2"
                     /candidate_cluster_numbers="3"
                     /contig_edge="False"
                     /product="lassopeptide"
                     /product="CDPS"
                     /region_number="19"
                     /rules="(PF13471 and Asn_synthase or micJ25 or mcjC)"
                     /rules="CDPS"
                     /tool="antismash"
     cand_cluster    1..33046
                     /SMILES=""
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PF13471 and Asn_synthase or micJ25 or
                     mcjC)"
                     /detection_rules="CDPS"
                     /kind="neighbouring"
                     /product="lassopeptide"
                     /product="CDPS"
                     /protoclusters="1"
                     /protoclusters="2"
                     /tool="antismash"
     cand_cluster    1..22581
                     /candidate_cluster_number="2"
                     /contig_edge="False"
                     /detection_rules="(PF13471 and Asn_synthase or micJ25 or
                     mcjC)"
                     /kind="single"
                     /product="lassopeptide"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..22581
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:12581](+)"
                     /cutoff="10000"
                     /detection_rule="(PF13471 and Asn_synthase or micJ25 or
                     mcjC)"
                     /neighbourhood="10000"
                     /product="lassopeptide"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..12581
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="(PF13471 and Asn_synthase or micJ25 or
                     mcjC)"
                     /neighbourhood="10000"
                     /product="lassopeptide"
                     /protocluster_number="1"
     misc_feature    230..241
                     /note="TFBS match to AfsR, Pleiotropic regulatory for
                     antibiotic production, confidence: medium, score: 18.46"
                     /tool="antismash"
     gene            complement(775..1554)
                     /locus_tag="K9S39_RS10955"
                     /old_locus_tag="K9S39_11045"
     CDS             complement(775..1554)
                     /EC_number="3.1.11.2"
                     /GO_function="GO:0004518 - nuclease activity [Evidence
                     IEA]"
                     /GO_process="GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019061999.1"
                     /locus_tag="K9S39_RS10955"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="K9S39_11045"
                     /product="exodeoxyribonuclease III"
                     /protein_id="WP_248863173.1"
                     /transl_table=11
                     /translation="MRIATWNVNSITARLPRLLAWLESTGTDVLCIQETKCSAEQFPHD
                     ELRELGYEAAINCNGRWNGVALLSKVGLEDVVCGLPGGPDYDGVQEPRAIAVTCGPARV
                     WSVYVPNGREVGHAHYAYKLNWFEALKTAVAQDAAGSRPFAVLGDYNVAPTDEDVWDPA
                     VFDGATHVTPAERAALSALREAGLTDVVPRPLKYDRPYTYWDYRQLAFPRNNGMRIDLV
                     YGNEPFAKAVSDAFVDREERKGKGASDHAPVVVDLDV"
     misc_feature    1524..1539
                     /note="TFBS match to LexA_variant_1, Repressor of DNA
                     damage response, confidence: weak, score: 21.73"
                     /tool="antismash"
     misc_feature    1525..1539
                     /note="TFBS match to IolR, Regulator of the inositol
                     catabolism, confidence: medium, score: 19.89"
                     /tool="antismash"
     gene            complement(1585..2223)
                     /locus_tag="K9S39_RS10960"
                     /old_locus_tag="K9S39_11050"
     CDS             complement(1585..2223)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018090403.1"
                     /locus_tag="K9S39_RS10960"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="K9S39_11050"
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="WP_248863174.1"
                     /transl_table=11
                     /translation="MELTKKTHACVRFRKDGQTLVIDPGLFSEEDAAVGADAILVTHEH
                     MDHFDEQRLRSGMEANPAAEIWTLASVAEQISAAFPGRVHTVGEGDTFTAAGFDIEVHG
                     QLHAVIHPDIPRITNVGYLLDGAVFHPGDALTVPEGRSVDTLLLPVHAPWNKVAEVIDY
                     VREVAPRRAIDIHDSLLQDHARPVYDSMIDKLGGSDHGRLAPGTTTELG"
     gene            complement(2596..3879)
                     /gene="pcaC"
                     /locus_tag="K9S39_RS10965"
                     /old_locus_tag="K9S39_11055"
     CDS             complement(2596..3879)
                     /EC_number="4.1.1.44"
                     /GO_function="GO:0047575 - 4-carboxymuconolactone
                     decarboxylase activity [Evidence IEA]"
                     /NRPS_PKS="Domain: Abhydrolase_1 (17-127). E-value:
                     1.7e-23. Score: 75.4. Matches aSDomain:
                     nrpspksdomains_K9S39_RS10965_Abhydrolase_1.1"
                     /codon_start=1
                     /gene="pcaC"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Abhydrolase_6"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF00561"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1036: alpha/beta hydrolase fold protein"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018090402.1"
                     /locus_tag="K9S39_RS10965"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="K9S39_11055"
                     /product="4-carboxymuconolactone decarboxylase"
                     /protein_id="WP_248863175.1"
                     /sec_met_domain="Abhydrolase_6 (E-value: 2.5e-14, bitscore:
                     53.3, seeds: 455, tool: rule-based-clusters)"
                     /sec_met_domain="PF00561 (E-value: 5.9e-18, bitscore: 64.3,
                     seeds: 48, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSEKTLQHRIDGPDDAPVLVLGASLGTTWHMWDRQIPELTRHWRV
                     IRFDLPGHGGSPAHPASSIAELADRLVTTLDGLGVERFGYAGCSIGGAIGTQLALTRPH
                     RVTSLALVSSSPRYGTADAWRQRGVVIRTNGLDPIARTAPEHWFTPGFAGAQPAIVEWA
                     VQMVRTTDPGCYIAACEALASYDVRSSLGRVGVPTLVVVGSEDQVTPTTDARTLVAGVP
                     DASLALVPGTSHLAPVEQPAAVTELLIRHFTTAWHDKPGPGTPAAIGAAAPKPQIGPPP
                     PPQEAPAAIESGLAQPEHARGGTYEQGIKIRREVLGDAHVDRVEAASDAFTGDFQDFIT
                     RYAWGETWTRPGLDRRTRSVITLTALVARGHQEELALHTRAALRNGLTPMEIKEVLLHT
                     AVYCGVPAANSAFAVAQRVIQEETTPEG"
     aSDomain        complement(3499..3828)
                     /aSDomain="Abhydrolase_1"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_K9S39_RS10965_Abhydrolase_1.1"
                     /evalue="1.70E-23"
                     /label="K9S39_RS10965_Abhydrolase_1.1"
                     /locus_tag="K9S39_RS10965"
                     /protein_end="127"
                     /protein_start="17"
                     /score="75.4"
                     /tool="antismash"
                     /translation="VLVLGASLGTTWHMWDRQIPELTRHWRVIRFDLPGHGGSPAHPAS
                     SIAELADRLVTTLDGLGVERFGYAGCSIGGAIGTQLALTRPHRVTSLALVSSSPRYGTA
                     DAWRQR"
     gene            4235..4534
                     /locus_tag="K9S39_RS10970"
                     /old_locus_tag="K9S39_11060"
     CDS             4235..4534
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="K9S39_RS10970"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="K9S39_11060"
                     /product="hypothetical protein"
                     /protein_id="WP_248863176.1"
                     /transl_table=11
                     /translation="MIHADHARQMLRMHAERLAQTATDTTLPNPAATTLPQADTLGGFL
                     EELTGQFAPHPGSLPRTVLPQTPPRDTGEEALDEERLLLATATRTPQGSKTCGG"
     gene            4534..5001
                     /locus_tag="K9S39_RS10975"
                     /old_locus_tag="K9S39_11065"
     CDS             4534..5001
                     /GO_function="GO:0003678 - DNA helicase activity [Evidence
                     IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_process="GO:0006260 - DNA replication [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF012974.5"
                     /locus_tag="K9S39_RS10975"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="K9S39_11065"
                     /product="DnaB-like helicase N-terminal domain-containing
                     protein"
                     /protein_id="WP_248863177.1"
                     /transl_table=11
                     /translation="MPEDFALPLHAALWQCLTSLVHRGDPVDPVTVRWEAQHRGLLTKD
                     VAPADLMTLVSTQAGSPEYWGEKVLHRALLARAHTVAVRIQAFTDDPANTPHQLITGSR
                     RALADLTSLRTRWQHATAPPPPTRPHASRTPAATRAGPPPTTAAPAARATR"
     gene            5284..6129
                     /locus_tag="K9S39_RS42960"
                     /old_locus_tag="K9S39_11070"
     CDS             5284..6129
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF015713.5"
                     /locus_tag="K9S39_RS42960"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="K9S39_11070"
                     /product="DUF317 domain-containing protein"
                     /protein_id="WP_406707902.1"
                     /transl_table=11
                     /translation="MGGRNAHLGRQHHHRHDESLTLRVLFDHDAESRDTKWTIAAYESP
                     VSDRIWHATATAATPVEIVGTPSSTLWPAKTRGPPGWGPTSRRRPSPRPPAPWPTPAGR
                     KQSKDVGSSGLRRTTTPPASSSTPSPPRNTTPAADLDHVGRQHPPPIHLGPALSPHTPA
                     GLLQDIAAELAHGQSVRQTPHPRPASRQTSPSAQAPASCPPHPPGCSSRVLDACLLKNG
                     PRCLSPDRWHPAPTRQHPSPLPLVGVGGASPPHGDLLVPRAVRAPTQTGPVRRAGATNG
                     "
     gene            6239..7468
                     /locus_tag="K9S39_RS10980"
                     /old_locus_tag="K9S39_11075"
     CDS             6239..7468
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1237: transposase"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005474440.1"
                     /locus_tag="K9S39_RS10980"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="K9S39_11075"
                     /product="IS110 family transposase"
                     /protein_id="WP_248868681.1"
                     /transl_table=11
                     /translation="MIYCGIDRAERTHDVTLVDDTGMLVAKRHITDDAAGYKLLLELLA
                     EHGDTEDSPIPVAIETSRGLLVAVLRTGKRKVYAINPLAAARYRDRHSVTRKKSDPGDA
                     LVLANILRTDIHAHRPLPDDSDLGRAIAVLARAQQDALWNRQQTANQLRSLLREYCPAA
                     LDAFATWTNGLCRPEARELLKTAPTPTRARRLTRSQLQATLKRAGRQRGIEAEADRLRD
                     VFRAKGAHQPPLVEDALGQQRLTLLLQLDAACTAADQLAKAVEEAFPQHPDAEILLSFP
                     GLGIQLAARMLAEIGDDRTRFADARGLKAYAGSSPITRASGKKSSITRRRVKNDRLSHA
                     GYPWAFSAPNGSPGAKAHYRRRRDEHGDWHAAALRNLFNRMLGQLYHCLQRRELFDERT
                     AFPTELAHAA"
     gene            complement(7678..8109)
                     /locus_tag="K9S39_RS10985"
                     /old_locus_tag="K9S39_11080"
     CDS             complement(7678..8109)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="K9S39_RS10985"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="K9S39_11080"
                     /product="hypothetical protein"
                     /protein_id="WP_248863178.1"
                     /transl_table=11
                     /translation="MSPHAVSAAFDDSNLVAHTGLVPVMRLAARGQLSELVRETVRIDG
                     ADNSGRTNPAAKVTSLIAAMCAGADSIEDADRRRHGAMPLLFGGIRAPSTLGTFLRSFT
                     HGHALQLHAVHRRFLSQLAAHTPLLPGAGQITFIEAPPS"
     gene            8332..>8821
                     /locus_tag="K9S39_RS10990"
                     /old_locus_tag="K9S39_11085"
                     /pseudo=""
     CDS             8332..>8821
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008749689.1"
                     /locus_tag="K9S39_RS10990"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /old_locus_tag="K9S39_11085"
                     /product="transposase family protein"
                     /pseudo=""
                     /transl_table=11
                     /translation="MGRAALSHPAFTGVSRAHLGGLIEELAAPWQARRESELREWCGGD
                     RRRQAGAGRKHELVFTDPVLVTLAHLRTQAPARRARRAVGRGPFHRHRGHRRNPSAAGR
                     PRVRCP"
     gene            complement(8870..>9202)
                     /locus_tag="K9S39_RS10995"
                     /old_locus_tag="K9S39_11090"
                     /pseudo=""
     CDS             complement(8870..>9202)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /GO_process="GO:0006313 - DNA transposition [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_033717843.1"
                     /locus_tag="K9S39_RS10995"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /old_locus_tag="K9S39_11090"
                     /product="transposase"
                     /pseudo=""
                     /transl_table=11
                     /translation="SMDAFGTSGRLAGVAGLAPVPRDSGRISGNLHRPRRYSRRLLRVF
                     YLSAQVAARSCPVSKRFYDRKRSEGKGHKQALLALARLRLNVLWALIRDGRPFESAPPQ
                     TDAAAA"
     misc_feature    9457..9475
                     /note="TFBS match to LexA_variant_3, Repressor of DNA
                     damage response, confidence: weak, score: 21.64"
                     /tool="antismash"
     gene            9864..9974
                     /locus_tag="K9S39_RS11000"
                     /old_locus_tag="K9S39_11095"
     CDS             9864..9974
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016638602.1"
                     /locus_tag="K9S39_RS11000"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="K9S39_11095"
                     /product="keywimysin-related RiPP"
                     /protein_id="WP_248863179.1"
                     /transl_table=11
                     /translation="MKKAYEAPTLVRLGTFRKRTGLLQRNGNDRLIFSKN"
     gene            10001..11851
                     /locus_tag="K9S39_RS11005"
                     /old_locus_tag="K9S39_11100"
     CDS             10001..11851
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lassopeptide: Asn_synthase"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1177: asparagine synthase (glutamine-hydrolyzing)"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015656043.1"
                     /locus_tag="K9S39_RS11005"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="K9S39_11100"
                     /product="lasso peptide isopeptide bond-forming cyclase"
                     /protein_id="WP_248863180.1"
                     /sec_met_domain="Asn_synthase (E-value: 1.5e-44, bitscore:
                     152.0, seeds: 78, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPTSYETGGVGPGDAHFAVLPDCADAVAAARSFRRPEARTLAHPS
                     GRPWLVGRWSDQEIVTAHAGWAAIAVVGCCPVGPDELKGYASRLRDLTELDALARRLSG
                     SFHLVAALDGRQRVQGTASGLRLVFHAAVDGVRVAATSADELAAAIGEEPDEERLAVRL
                     LWPAPYPLSETSLWRGVTAVPPEDALIVAPDGRTARHSRWWTPPDPVRSLAENAPLVRE
                     ALSDAVDARTSAGGVVSCDLSGGLDSTSVCFLAARSPAHVVASTWPGRDPADSDLYWAQ
                     KAAGFLPDVEHVIWDADESPLVYDDLLAVDDLIDEPTIGVMDRSRVLHHLPALGQRGSR
                     LHLTGIGGDHVAWCSEAYYHRLIRTRPLLALRHLRGFRTLFHWPLGATARALADSRSYG
                     QWLAHAGRQLREAKAPPVSGTLGWGSPPRLFDWITPETARIVGRALRDAAESAQPLHPD
                     RGMHADLEQIRVCTRIVRQWDRMAARAGVPMASPFFDDRVIEACLAVNPVERVTPWAYK
                     PLLTAAMRQIVPDVCLERANKAQASMDATNGLRERRGDLMELWEDSHLARLGLVDGRAL
                     MELARRPSTPGLNEGNLYSTIACEVWLRSLSRKRREVSSG"
     misc_feature    10265..10267
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            11896..12150
                     /locus_tag="K9S39_RS11010"
                     /old_locus_tag="K9S39_11105"
     CDS             11896..12150
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lassopeptide: Stand_Alone_Lasso_RRE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Lasso_Fused_RRE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF05402"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016638601.1"
                     /locus_tag="K9S39_RS11010"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="K9S39_11105"
                     /product="lasso peptide biosynthesis PqqD family chaperone"
                     /protein_id="WP_248863181.1"
                     /sec_met_domain="Lasso_Fused_RRE (E-value: 4.9e-06,
                     bitscore: 25.5, seeds: 20, tool: rule-based-clusters)"
                     /sec_met_domain="Stand_Alone_Lasso_RRE (E-value: 2.6e-26,
                     bitscore: 90.4, seeds: 25, tool: rule-based-clusters)"
                     /sec_met_domain="PF05402 (E-value: 3.1e-16, bitscore: 58.3,
                     seeds: 461, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MALRFASDITTAETDYGTVLLDQRNGHYWELNPTGTLVVRTLLEG
                     GEEADAVDAVIAEFDIDRSQATQDVAALIESLRTSGLTA"
     aSDomain        11899..12141
                     /aSDomain="Stand_Alone_Lasso_RRE"
                     /aSTool="RREfinder"
                     /database="RREFam.hmm"
                     /description="Stand-alone RRE protein in a lasso peptide
                     cluster"
                     /detection="hmmscan"
                     /domain_id="rrefinder_K9S39_RS11010_Stand_Alone_Lasso_RRE.1
                     "
                     /evalue="8.70E-29"
                     /identifier="RREFam002.1"
                     /label="K9S39_RS11010"
                     /locus_tag="K9S39_RS11010"
                     /protein_end="82"
                     /protein_start="1"
                     /score="90.4"
                     /tool="antismash"
                     /translation="ALRFASDITTAETDYGTVLLDQRNGHYWELNPTGTLVVRTLLEGG
                     EEADAVDAVIAEFDIDRSQATQDVAALIESLRTSGL"
     gene            12147..12581
                     /locus_tag="K9S39_RS11015"
                     /old_locus_tag="K9S39_11110"
     CDS             12147..12581
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lassopeptide: PF13471"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016638600.1"
                     /locus_tag="K9S39_RS11015"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="K9S39_11110"
                     /product="lasso peptide biosynthesis B2 protein"
                     /protein_id="WP_248863182.1"
                     /sec_met_domain="PF13471 (E-value: 5e-25, bitscore: 86.7,
                     seeds: 84, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTTPSALTRPTGVPLARRLVARLVFIAAVLLSFLPPRRIRAVLEA
                     VRHGAAPASAAQAKSARDAMCAVSLLCAGPRGCLPRSLGTALLCRLGGTWPTWCTGVGK
                     VPPFMAHAWVEIDGRLVGEGVPDDYFNRLLTVPPVRRATR"
     cand_cluster    12405..33046
                     /candidate_cluster_number="3"
                     /contig_edge="False"
                     /detection_rules="CDPS"
                     /kind="single"
                     /product="CDPS"
                     /protoclusters="2"
                     /tool="antismash"
     protocluster    12405..33046
                     /aStool="rule-based-clusters"
                     /category="NRPS"
                     /contig_edge="False"
                     /core_location="[22404:23046](-)"
                     /cutoff="5000"
                     /detection_rule="CDPS"
                     /neighbourhood="10000"
                     /product="CDPS"
                     /protocluster_number="2"
                     /tool="antismash"
     proto_core      complement(22405..23046)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="5000"
                     /detection_rule="CDPS"
                     /neighbourhood="10000"
                     /product="CDPS"
                     /protocluster_number="2"
     gene            12578..14404
                     /locus_tag="K9S39_RS11020"
                     /old_locus_tag="K9S39_11115"
     CDS             12578..14404
                     /EC_number="7.-.-.-"
                     /GO_component="GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1288: ABC
                     transporter related protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016638599.1"
                     /locus_tag="K9S39_RS11020"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="K9S39_11115"
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_406707903.1"
                     /transl_table=11
                     /translation="MSGKAAAARADGPSVRGAIAAMFRLTAGHRSSMTVASVLTLGGSA
                     LGLAQPLLAKTIVDASAHGHVVGPVLVLAALFVAEAATGAVGRFVLERMGERVVRGLRS
                     SLVSRLLRLEMREYDRHRTGDLISRVTTDTSLLREVVSQALVDLMTGSLVALGAVALML
                     WIDPLLLLLVTLTVVAAVSVMASLLTGLRTAAEHMQGAIGTVAAELERALGALPMVRVH
                     RAEEREAERMGRCIDTAYSAGVRTARLSSVLSPAVELAVHGSFLLVLVIGGLRVNGNAN
                     TLGDLVAFMLYATYLVVPLSSVFRAVGLVQRGMGAFQRIDEALALQAEPAEPEPPARQA
                     PARCSPRPAPAAPEPALALDDVWFGYRPCRPVLQGISLTVPPRRQVALVGRSGAGKSTI
                     FALIARFYEPDSGTLRFDGRPAAELGRKECRARIAVVDQNTHVVHGSLWDNITYAAPTA
                     SPAEVQRAVELANLTDVVNRLPGGLDGTVGERGNTLSAGERQRVALARALLTRPSLLLL
                     DEPTSHLDAINEAALSHVLQDVTRQCALLVIAHRLSTVQNADQIILLEAGRAIASGRHE
                     DLLTTSAAYRELASGQALRTQGTNGRGAMRLH"
     gene            complement(14781..15758)
                     /locus_tag="K9S39_RS11025"
                     /old_locus_tag="K9S39_11120"
     CDS             complement(14781..15758)
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1237: transposase"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004939370.1"
                     /locus_tag="K9S39_RS11025"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="K9S39_11120"
                     /product="IS110 family transposase"
                     /protein_id="WP_248863183.1"
                     /transl_table=11
                     /translation="MDTASFPATAVGYRELWEWASRLGTVHKAGVEGPGSYGAALSRYL
                     LARRVEVFEVNRPDRSVRRRCGKSDPVDAQEAARSVLSGRAHSQAKAGDGPVQCARLFK
                     LAKDSAVKARTQAINQLKAVLITADPDLREQLAGLKAPALVRTCAQFEERAGDDGERDA
                     VGQATRIALCLLAQRIDQLTGQILDLERRLTGLVERHFPQLLIPVGIGPDSAATLLITM
                     GDNLERLRTEASFAALCGVSPVEYSSGRQRRHRLNRGGDRRANGALYRIVQSRLRFDAR
                     TRNYYERRTAEGKTRREIIRCLERYAAREVFNLVRSGIGPREVA"
     gene            15822..16385
                     /locus_tag="K9S39_RS11030"
                     /old_locus_tag="K9S39_11125"
     CDS             15822..16385
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020114957.1"
                     /locus_tag="K9S39_RS11030"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="K9S39_11125"
                     /product="hypothetical protein"
                     /protein_id="WP_248863184.1"
                     /transl_table=11
                     /translation="MAERCAVASVLGMLEEREAAARVRVEGLREEAARLAAVLEAAEIE
                     LDRRVIAREELVEALAASAAESTAVTEAEAEAEAEKGTVPVSVPMPGSTVPSWREGLPV
                     TVLAPDYQRIVGVLDEQRSAGKGPVKAKEVAVELGLQATPAKVEGVRSKARRLAERGWL
                     LQETSGMFSAGRRPVAAPDAGSSA"
     gene            complement(16465..16734)
                     /locus_tag="K9S39_RS11035"
                     /old_locus_tag="K9S39_11130"
     CDS             complement(16465..16734)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /GO_process="GO:0006313 - DNA transposition [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1097: transposase"
                     /gene_kind="other"
                     /inference="COORDINATES: protein motif:HMM:NF013752.5"
                     /locus_tag="K9S39_RS11035"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="K9S39_11130"
                     /product="transposase"
                     /protein_id="WP_248863185.1"
                     /transl_table=11
                     /translation="MTDCLGLLLVVAVTAANIGDRDAALGLLTRLRRLHRDITLVWADG
                     GYTGSLVDWCRDKLALTLEIVKRTDDTTGFVVMPRRWVAERTFA"
     gene            complement(16862..19195)
                     /locus_tag="K9S39_RS11040"
                     /old_locus_tag="K9S39_11135"
     CDS             complement(16862..19195)
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1077: phage integrase
                     family protein"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014140677.1"
                     /locus_tag="K9S39_RS11040"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="K9S39_11135"
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="WP_248863186.1"
                     /transl_table=11
                     /translation="MTALVSPSTNPDLADRWAWPIDPGRYDTAAAVRPAEKRAIAELGL
                     VNLRRMARHDPDAPGWKAIRRLLRPLDDVAAALHEPATSHRRRGRLDAAAVVLLRCAET
                     GRSYWAWSGEEWAHLLGKDLQGFRASVPAWAEEAARPQLAVHAFLLGGFADFYKLGSFG
                     RLALAWRVFGRDRVDGEIRRIRKVLARWGYQLGREDDQLLPMVVCQVLLLNRSPHLEDL
                     TTNLFEQIRAERLLPAARGNTLHAMQRAVAELGFCDPPQRMTGRHSARASGGSPAWATW
                     VERWYDTSTLTTRVRGSLRATLFKVGRWIEAEHPEAADPAEWTRKTCATWVAAVDRMKV
                     GDYLQRTAGLKDHLGKPLEAPSKAGHLTAVRTFFRDLQEWEWIPRRFDPQRALGTPRSI
                     AALLGPDPRVIADDIWAKLMWAGLNLTEDDLPQTQAGNFYPLELVRAVTLTWLFSGQRS
                     DEIARLRTGCIRWEHDGTVIAGDSQQVLARDAVCLLDVPTHKTGTAFTKPVDPILGQAL
                     DTWQAVRPVQPKFTDRRTGELVDPLFAFRARKVSSVYINNTVIPMLCRKAGVPAADVRG
                     NITSHRARSTIASQLYNAKEPMTLFELQAWLGHSSPQSTQFYAKISPTTLTRAYDDAGY
                     FSRNVRTIEVLVDRDAVTSGAAAAGEPWQHYDLGHGYCTYTFFEQCPHRMACARCDFYT
                     PKDSSKAQLLEGKGNLQKMRAMIPLSEDEQAAVDDGQAALDRLLGRLADIPTPAGPTPR
                     QFDVPPNATLLPIVDVQQGKAPQA"
     gene            complement(19192..20259)
                     /locus_tag="K9S39_RS11045"
                     /old_locus_tag="K9S39_11140"
     CDS             complement(19192..20259)
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1077: phage integrase
                     family protein"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005484839.1"
                     /locus_tag="K9S39_RS11045"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="K9S39_11140"
                     /product="site-specific integrase"
                     /protein_id="WP_248863187.1"
                     /transl_table=11
                     /translation="MSGTTVLTEKWPVLGRHEQAAAWLTIWTDLGRAPRTIDAYGRGLA
                     EYLLMCEREDVDPVTANRAHVAIYVRELTSRPHRWGVNVISIDSGAGLANATIQQRLVP
                     VRLFYDFLMEEGLRESNPVGRGRYTPGRQGGGQQRGLVPRLTKLPWIPGEEQWLQILEV
                     ARHEPVRNRVMLALAYDAALRREELCSLRTDDLDPAHRTLRIRAETTKNRLERVVPYSA
                     STGVLLSGYLAHRASISRARGPLFLSESRRNHAQPLSLWTWSKVIRRIALASGVERFST
                     HTTRHLCLTDLARMGWEVHAIASFAGHRHTDSTLQYIHLSGRDLADKLSRGMEHIHAWR
                     IQALTRDDAAGEAGR"
     misc_feature    complement(20848..20859)
                     /note="TFBS match to AfsR, Pleiotropic regulatory for
                     antibiotic production, confidence: medium, score: 18.46"
                     /tool="antismash"
     misc_feature    21126..21138
                     /note="TFBS match to MatP, Cell cycle regulator,
                     confidence: weak, score: 19.5"
                     /tool="antismash"
     gene            complement(21135..22343)
                     /locus_tag="K9S39_RS11050"
                     /old_locus_tag="K9S39_11145"
     CDS             complement(21135..22343)
                     /GO_function="GO:0004497 - monooxygenase activity [Evidence
                     IEA]"
                     /GO_function="GO:0005506 - iron ion binding [Evidence IEA]"
                     /GO_function="GO:0016705 - oxidoreductase activity, acting
                     on paired donors, with incorporation or reduction of
                     molecular oxygen [Evidence IEA]"
                     /GO_function="GO:0020037 - heme binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) p450"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1007: cytochrome P450"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF012296.5"
                     /locus_tag="K9S39_RS11050"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="K9S39_11145"
                     /product="cytochrome P450"
                     /protein_id="WP_248863188.1"
                     /sec_met_domain="p450 (E-value: 3.2e-21, bitscore: 74.5,
                     seeds: 50, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTHPTDDPGLPLRYPFPPGELGTPPPVLAWARKKQPVCPVALPSG
                     DRVWMVTRKDDITHVLTDPRFSRNLTYPGAPRFVGDDFTSVPGGIFNLDPPDHTRVRQV
                     ISRFYTRSAVEHHRPMIEQHAAQLLDDMAHGPNPADLMPAYADALPLHVAREILAVPSE
                     LHSLYHSCFRTQTHLAASAEAVAEATAAITDFTKEVIETKRRHPDPNEPIGALILARYD
                     GLISEDELIGTTSYLFVTGSEPLTASFGTGTVTLLTNPRQLRECITAPDLWPKAVEEIL
                     RYHHNGVLGMPRVATTDVTLHDVTIRKGEGVCCPMLGATHDPAHYPNPFRFNIHRTTDG
                     SATFGAGPHFCLGAPLARLFLQTAYRALFTRFPSLFLALPEREIPWEDNLVFIKPASLP
                     VAW"
     gene            complement(22405..23046)
                     /locus_tag="K9S39_RS11055"
                     /old_locus_tag="K9S39_11150"
     CDS             complement(22405..23046)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters) CDPS:
                     CDPS"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:TIGR04539.1"
                     /locus_tag="K9S39_RS11055"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="K9S39_11150"
                     /product="tRNA-dependent cyclodipeptide synthase"
                     /protein_id="WP_248863189.1"
                     /sec_met_domain="CDPS (E-value: 9.1e-50, bitscore: 168.3,
                     seeds: 17, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEFLIRPCTDDSRNILNRAEHVLIGLSPWNGYYKPRTVEALVEWA
                     CANFAAVDVFVPGYEAAHTLTAAGLPPREAVHRTRRAVSQLRNPAQRALRRTGITDPEL
                     RFHSWTQLVNRPAYQHTLKRVRHAYRTDEAVRRACRLTARGAVLHAAGHEPTEQQIDQA
                     VSYAIAELPLVLDAPAIFETESTGTWISSPPSSPARPPGSAPPPDRDTPW"
     gene            complement(23060..23281)
                     /locus_tag="K9S39_RS42965"
                     /old_locus_tag="K9S39_11155"
     CDS             complement(23060..23281)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="K9S39_RS42965"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="K9S39_11155"
                     /product="hypothetical protein"
                     /protein_id="WP_406707904.1"
                     /transl_table=11
                     /translation="MIDVDARRWSARVHERALRTAGFTTVDWIRPEVSEAGRRWFGDDH
                     WTNYLSCPHALIIDAIAGPDDAPGSGTR"
     gene            complement(23238..23840)
                     /locus_tag="K9S39_RS42970"
                     /old_locus_tag="K9S39_11160"
     CDS             complement(23238..23840)
                     /EC_number="2.1.-.-"
                     /GO_function="GO:0008168 - methyltransferase activity
                     [Evidence IEA]"
                     /GO_function="GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1248: methyltransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF013382.5"
                     /locus_tag="K9S39_RS42970"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="K9S39_11160"
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="WP_406707905.1"
                     /transl_table=11
                     /translation="MDSQFDSIVAAYEQSMNRLPFREHVEAYSLLKAIGSLTGLAVLDL
                     GCGTGLYARRFRALGAKRVVGMDTSQSMIEYARRKEEQERHGITYVHHNATRSLDDGLA
                     GAFDLVTSVYVLPYATSENDLAGMCATARQALSPRGAVRRDDPQPRLRHPPRLVPQLRH
                     DAHHGPARRRRGHGPSDSAGRRPRDRRRRPPVVGPRP"
     gene            24128..25492
                     /locus_tag="K9S39_RS11065"
                     /old_locus_tag="K9S39_11165"
     CDS             24128..25492
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="K9S39_RS11065"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="K9S39_11165"
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="WP_248863191.1"
                     /transl_table=11
                     /translation="MRHPLKAARESLGLSQTAYARLIAKAHNELGFGPKMVKTHYTVLH
                     WESGRNEPEPNTQLAIAHIHGVNLEDVLRLGWPHWLHLATDDATLLNQSWTPQSAIDAL
                     HSTARLADTRPRSYLAVTGPALDSQIRATLAALADPQPPPSREGRRVTPDTLTRIEARI
                     EALELQEARALTTPMALYFATRAEHRLLTTLLTSSGYDHKAGARLLLLAARTAALCAWL
                     SGCLGEDARAERYALAAIRAASVAGARRHVAAYMPDLAFRHLVAGDPKDVLSLVHATRA
                     IVRHPSPGLAVTLHSREAQALARLGDITASTRALDRAVSTLVTGPTEVDPTIDPLSINV
                     DEEWLDVSSGAAWLHLGRPEKALPHLTTLLDDGPPSRPPTPPSPCAASRLLYVVDAQLA
                     LGELDAATHSAHRAAALVGNLPPDLAHQFRQRFAPHTTEPAVRDLIDTLTEHPTH"
     gene            complement(<25907..>26035)
                     /locus_tag="K9S39_RS11075"
                     /old_locus_tag="K9S39_11175"
                     /pseudo=""
     CDS             complement(<25907..26035)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005483586.1"
                     /locus_tag="K9S39_RS11075"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /old_locus_tag="K9S39_11175"
                     /product="site-specific integrase"
                     /pseudo=""
                     /transl_table=11
                     /translation="MGATTVAKSYRLLSAIMEIAADDELIRRNPCRIKGAGKESAEE"
     gene            complement(26173..26394)
                     /locus_tag="K9S39_RS11080"
                     /old_locus_tag="K9S39_11180"
     CDS             complement(26173..26394)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF024949.5"
                     /locus_tag="K9S39_RS11080"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="K9S39_11180"
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="WP_248863192.1"
                     /transl_table=11
                     /translation="MRTARTIEIVRTECGLAQRQLADRVTGLGRPMSNTMLSRIERAQR
                     CCDADDLVAIADALRFSPFALLQGPAAP"
     gene            27218..28510
                     /locus_tag="K9S39_RS11085"
                     /old_locus_tag="K9S39_11185"
     CDS             27218..28510
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005481948.1"
                     /locus_tag="K9S39_RS11085"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="K9S39_11185"
                     /product="ATP-binding protein"
                     /protein_id="WP_248863193.1"
                     /transl_table=11
                     /translation="MTQHIPEAVFWCLAAVTLAGVSLLVRQYRITAALRRRLTIHEAGL
                     LAREEEVRHLSEVRLPALVEAAHGSAPVPGPLDADLAGTTYGKNLQQIVEQFTGAAEAT
                     RSRADRSAKATLKSAMRALQALANEQQVSISDMQDRHDDPDVLRDLLEIDHANAQFGRR
                     TQAIAMLCGSWPGRQRTASPLLDVVRGATSRIRDYRRVKVHSRVDMDVVSRAVEPVVLA
                     VAELLDNAARHSRPNTTVEVGIQPAHNGVSIVVDDAGIGMDARETEEAGRRLSGLVDID
                     INKLGSPPQFGFAVIGALAARYGFSVSVNTQSPYGGVRAVLFLPNALLNRVRFMGPPIP
                     ALGAETPPAPEPASPGASEEAAPSSTAGGLPKRRRCTQQHQAADGGPEAPASTPALVRP
                     AAETASRMGAFARGTRSGRDSSPDTEGTPQE"
     misc_feature    27226..27246
                     /note="TFBS match to MntR, Manganese transport regulator,
                     confidence: weak, score: 20.82"
                     /tool="antismash"
     gene            28507..28941
                     /locus_tag="K9S39_RS11090"
                     /old_locus_tag="K9S39_11190"
     CDS             28507..28941
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004948169.1"
                     /locus_tag="K9S39_RS11090"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="K9S39_11190"
                     /product="roadblock/LC7 domain-containing protein"
                     /protein_id="WP_248863194.1"
                     /transl_table=11
                     /translation="MTGQMTNELGWMLDEVLKVPEARHAILLSADGMLRAHSQGIKRDE
                     AERQAAALSGLQSISRSTAEFCGLETSPWQQTLVEFADGYVFLVAAGTGAYLAVSAGQD
                     VDMEAVTYSMHKLVDRLGKELTSLPRQHSVPGRPDDSGTA"
     gene            28938..29300
                     /locus_tag="K9S39_RS11095"
                     /old_locus_tag="K9S39_11195"
     CDS             28938..29300
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014055430.1"
                     /locus_tag="K9S39_RS11095"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="K9S39_11195"
                     /product="DUF742 domain-containing protein"
                     /protein_id="WP_248863195.1"
                     /transl_table=11
                     /translation="MTPPRPPHDRGLVRPYVVTEGRAHPTRNTLDVVALVTAVHDRPLK
                     GLSPEKRRVIELCRPGALSVAEVAGHLTLPMSVTKVLLSDLVDSGHVHVRPPVPKAQLP
                     DARFLQEVLDGLRSRF"
     gene            29278..29886
                     /locus_tag="K9S39_RS11100"
                     /old_locus_tag="K9S39_11200"
     CDS             29278..29886
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018385838.1"
                     /locus_tag="K9S39_RS11100"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="K9S39_11200"
                     /product="ATP/GTP-binding protein"
                     /protein_id="WP_248863196.1"
                     /transl_table=11
                     /translation="MGSAPVSDPVDPIYVSDTVTTAIKILVVGHFAVGKTTFVGTLSEI
                     RPLRTEETMTQAGELVDDLAGVPDKTTTTVAMDFGRLTLNESLVLYLFGAPGQKRFTQL
                     WKDMLNGALGALVLTDTRRLDQSFDIMGLLEEHGMPYAVAVNQFDGAPVFPEAEIREAL
                     DLLPETPLVTCDAREATSGAGALISLIEYLQTRTPQEQE"
     gene            29883..31139
                     /locus_tag="K9S39_RS11105"
                     /old_locus_tag="K9S39_11205"
     CDS             29883..31139
                     /GO_function="GO:0004497 - monooxygenase activity [Evidence
                     IEA]"
                     /GO_function="GO:0005506 - iron ion binding [Evidence IEA]"
                     /GO_function="GO:0016705 - oxidoreductase activity, acting
                     on paired donors, with incorporation or reduction of
                     molecular oxygen [Evidence IEA]"
                     /GO_function="GO:0020037 - heme binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1007: cytochrome P450"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014180161.1"
                     /locus_tag="K9S39_RS11105"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="K9S39_11205"
                     /product="cytochrome P450"
                     /protein_id="WP_248863197.1"
                     /transl_table=11
                     /translation="MTTPRPAHHAAPPLDCPAHAGARTVERLYGPEFAADPMASYTRLR
                     AHGSVAPVEIAPGVRASLVIGYDTALEVLRSPERFSKDPRRWRALADGTVPADSPVVPM
                     MAYRPNALWTDGDDHSRLRGAITDSLGRVDPDALMRHVEHSADTLIDRIGPKGRADLLH
                     EYGAVLPLLVFNELFGCPPATGDKLVEGMSGIFDADAGSEKANAVLAEGVAELVALKRA
                     EPGPDVTSWLMAHPAGLTDEEMSHQLVVLLGVGTEPQLNLICNGLRLLLSDDRFAGDLA
                     RGTMPVEDAIDEVLWTDPPMANYAVHYPIHDQELDGTLVCEGEPILISLAAANTDPGLS
                     GERRTGNRAHLAWSAGPHTCPAKGPARVIAAVALEKLLDRLPNIELEIPVEKLEWRQGP
                     FHRALAGLPVRFPPISRRV"
     gene            complement(31214..31396)
                     /locus_tag="K9S39_RS11110"
                     /old_locus_tag="K9S39_11210"
     CDS             complement(31214..31396)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="K9S39_RS11110"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="K9S39_11210"
                     /product="hypothetical protein"
                     /protein_id="WP_248863198.1"
                     /transl_table=11
                     /translation="MEHANAGHRHWRPLQRFTARRETYAEIHRAVAGLVSDRAARRATV
                     RKPSTEPVLAHRVSR"
     gene            31471..31644
                     /locus_tag="K9S39_RS11115"
                     /old_locus_tag="K9S39_11215"
     CDS             31471..31644
                     /GO_function="GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF012514.5"
                     /locus_tag="K9S39_RS11115"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="K9S39_11215"
                     /product="NUDIX domain-containing protein"
                     /protein_id="WP_248868683.1"
                     /transl_table=11
                     /translation="MHHLATGKWLLPGGHLEPEDNTHLQAAGRKLTEETGIPTHVLTPH
                     GETPLQHRRPPH"
     gene            complement(31595..31927)
                     /locus_tag="K9S39_RS11120"
                     /old_locus_tag="K9S39_11220"
     CDS             complement(31595..31927)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="K9S39_RS11120"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="K9S39_11220"
                     /product="hypothetical protein"
                     /protein_id="WP_248863199.1"
                     /transl_table=11
                     /translation="MDQACPCLSLPLSLARDRPGLGKGAAGRSSRRRCRVEQGLGDVLP
                     QGRVADGVDLAPGGVGDLFGLEFSDVGGGVEGKAEIEVLVGGLVLGGVGVNGVDVDVAA
                     GSRRAA"
ORIGIN
        1 cggcgtgatc aaccacggca tctcggcgaa ccgcattgtc accgaccgct atcagggcga
       61 cggggtcagc aaggacaccg gcggggtcag cgcccagcac cggctggagc gggatgtact
      121 ggcgcagccc gccgcgcgga ccgtcatcgt cttcgagggc atcaacgatg tgcggtgggg
      181 caccgcggcg ggcaaggtca tcgacggcct gcgggccatc gcccggcggg cacacgaacg
      241 cggcctgcgg gtcgtggcgg ccaccatcgc gccctgcgag ggctaccccg actgcacccc
      301 cgccgtcgaa gcccgccgcc aggccgtcaa cgccttcatc cgtgcccatg gcggcgtctt
      361 cgacgcggtg ctcgacttcg atgccgtact ccgcgatccg cagcgccccc agcggatgct
      421 gcccgtctac gacagcggcg accatctcca ccccggcgac gcgggcttga aggcactcgg
      481 cgactcggtg gacctcaggg cgctggtgcc gccggagcga aacagctgag gacgggcgaa
      541 ccgggggccg cagacaggcc atcatccccg acccgggcgg ggcgccgctg acgacaggca
      601 ggcccagggc cgtcgccaag ccgtcatccg cgacccggac ggggggctct gaggacgggc
      661 ccggcccggg acaccccagg ccgccatccg cgcccgggca ggggctgctg aggataggca
      721 ggcccggccc gggaccgctg cggaaaggca ggccggcccg gtccgggacc gctcctaaac
      781 atccagatcc accaccaccg gtgcatggtc cgaggcaccc ttgcccttgc gctcctcgcg
      841 gtcgacaaag gcgtccgaga cggccttggc gaacggttcg ttgccgtaga ccaggtcgat
      901 acgcatgccg ttgttcctgg ggaaggcgag ctgacggtag tcccagtacg tatacgggcg
      961 gtcgtacttg agggggcggg gtaccacatc cgtcaggccc gcctcgcgga gcgcggacag
     1021 cgcggcgcgc tcggccgggg tgacatgggt ggcgccgtcg aagacggcgg ggtcccagac
     1081 gtcctcgtcg gtcggcgcca cgttgtagtc gccgaggacc gcgaaggggc gggagcctgc
     1141 ggcgtcctgg gcgactgccg tcttcagtgc ctcgaaccag ttgagcttgt aggcgtagtg
     1201 cgcatggccg acctcgcggc cattggggac gtacaccgac cagacgcggg ccgggccgca
     1261 ggtcaccgcg atggcgcggg gctcctgcac gccgtcgtag tccggaccgc cgggcaggcc
     1321 gcagacgacg tcctccagac ccaccttgga caggagggca acgccgttcc accggccgtt
     1381 gcagttgatg gcggcttcat agcccagctc gcgcagctcg tcgtgcggga actgctcggc
     1441 cgagcacttg gtctcctgaa tgcacagcac gtccgtgccg gtgctctcca gccaggccag
     1501 cagcctcggg aggcgggcgg tgatcgaatt gacgttccag gtcgcgatgc gcatatccgt
     1561 aaacctacag ccagggtctg acagtcagcc gagttcggtg gtggtgccgg gcgcgagacg
     1621 gccgtgatcc gacccgccca gtttgtcgat catggagtcg tagaccggcc gggcgtggtc
     1681 ctggagcagg ctgtcgtgga tgtcgatggc ccggcggggc gcgacctccc ggacgtaatc
     1741 gatgacctcg gcgaccttgt tccaaggggc gtggaccggc agcagcagcg tgtcgacgct
     1801 gcggccctcg gggacggtga gcgcgtcgcc cggatggaag accgctccgt cgaggagata
     1861 tccgacgttg gtgatgcgcg ggatgtcggg gtggatgacg gcgtgcagct gtccgtgcac
     1921 ctcgatgtcg aagcccgctg cggtgaaggt gtccccctcc cccacggtgt gcacccggcc
     1981 ggggaacgcg gccgagatct gctcggcgac gctggccagc gtccagatct cggcggccgg
     2041 attggcctcc atgccggacc gcagccgctg ctcgtcgaag tggtccatgt gctcatgggt
     2101 gaccaggatc gcgtccgcgc cgacggccgc gtcctcctcg ctgaagagac cggggtcgat
     2161 gacgagcgtc tgcccgtcct tccggaaccg gacgcaggca tgggtcttct tcgtgagttc
     2221 catacggcca tcttgccggg cgcggggggt tgggaggggc acggggcgcg ggatgggagg
     2281 gggcacgggg tggcaggggc gcgcggcgcc gcgtgaaact gcgtcgctac gggcgccgac
     2341 cggaaccggg cccactacgg gcgcggccgg aaaccacacc actacacccg cccacccccc
     2401 gaaggggggt gggcggcggg gaaaaatcca ggggcgcggc gcacgaacga gagcagtccc
     2461 cgcacgaatg agggcaggcg caacggggcc aagccccgcg cgagcgaggg tcaagccccc
     2521 agcgccccgg gccccgagag aagcccctcc ccgctcaccc cttcccgctc ccccttccca
     2581 ctcatccctc gcccctcacc cctccggcgt cgtctcctcc tgtatcaccc gctgggccac
     2641 cgcgaaggca gaattcgcgg ccgggacgcc gcagtagacc gcggtgtgca gcaggacctc
     2701 cttgatctcc atgggagtga ggccgttgcg cagcgccgcg cgggtgtgca gcgccagttc
     2761 ttcctggtgg ccgcgggcga ccagcgcggt gagcgtgatg acgctccggg tgcggcggtc
     2821 cagcccgggc ctggtccagg tctcgcccca ggcgtaacgg gtgatgaagt cctggaaatc
     2881 gccggtgaag gcgtcggacg cggcctcgac gcggtcgaca tgggcgtcgc cgagcacctc
     2941 gcggcggatc ttgatgccct gctcgtacgt gccaccacgg gcgtgttccg gctgggcgag
     3001 gccggactct atggcggccg gggcctcctg cgggggcggc ggaggcccga tctgcggctt
     3061 gggggcggcg gcgccgatcg cggccggcgt accggggccc ggcttgtcgt gccaggcggt
     3121 ggtgaagtgt cggatgagga gttcggtgac ggccgcgggc tgttcgacgg gcgcgaggtg
     3181 cgaggtgccg ggcaccagcg cgaggctcgc gtccgggacg ccggcgacca gggtacgggc
     3241 gtcggtggtc ggggtgacct ggtcctcgga gccgacgacg acgagcgtgg gcacaccgac
     3301 ccggccgagg gaggaccgta cgtcgtacga ggcgagcgcc tcgcaggcgg cgatgtagca
     3361 gccggggtct gtggtccgca ccatctggac ggcccactcg acgatggccg gctgggcacc
     3421 cgcgaagccg ggtgtgaacc agtgctcggg ggcggtgcgg gcgatcgggt cgagcccgtt
     3481 cgtacggatg acgacaccgc gttgccgcca ggcgtcggcg gttccgtagc gtggcgagga
     3541 ggacaccagc gccagggagg tgacccggtg cgggcgtgtg agggccagct gggtgccgat
     3601 ggcgccgccg atgctgcagc cggcgtagcc gaagcgctcc acacccagtc cgtcgagcgt
     3661 ggtgaccagg cggtcggcca gttcggcgat ggacgaggcc gggtgggcgg gcgagccgcc
     3721 gtgaccgggc aggtcgaaac ggatgacgcg ccagtggcgg gtcagctcgg gaatctgccg
     3781 gtcccacatg tgccatgtgg taccgagcga ggcgcccagt acgagtacgg gggcatcgtc
     3841 ggggccatcg atccggtgct gcagggtctt ctcgctcacc cggccacgct accgaactct
     3901 ctgacgcggt cctgacaccc gggtcaggaa gagccgacac gaggggccaa ggcgtggccg
     3961 ccagccgcac ccaaagcggg gaagcgcagg tcagagtctc acggtcgaga cggcgtagac
     4021 gaccgggtga cccgactcga cgtagctcac catgatccgc tgtacggatg cggtgccttg
     4081 ctcgtgatca ggaccggggc gtcttctggc ccatcaaggc ggtactggag agtgcgcgtc
     4141 ggtatctcgc cacgccctgc acgctctcac atctcacctc cacaccctca tccaggtttg
     4201 cccctggccc aagcacgcgg cgacgtacgc acggatgatc cacgccgatc acgcccgcca
     4261 gatgctgcgc atgcacgccg aacgcctggc ccagaccgcg accgacacca ccttgcccaa
     4321 cccggccgcc actaccctcc cccaggccga cacgcttgga gggttcctgg aggaactcac
     4381 cggccagttc gccccgcacc ccggctcact tccccgcacc gtgctgcccc agacacctcc
     4441 gcgggacacc ggcgaggaag ccctggacga ggaacggcta ctgctcgcga ccgcgacgcg
     4501 caccccgcag ggctcaaaga catgcggtgg ctgatgcccg aggacttcgc cctgcccctg
     4561 cacgccgccc tctggcagtg cctgacctcg ctcgtccacc gcggtgatcc cgtcgatccg
     4621 gtcaccgtgc ggtgggaggc ccagcaccgc ggcctcctca ccaaggacgt cgccccggcc
     4681 gacctcatga ctctcgtctc gacgcaggcc ggctcacccg agtactgggg cgagaaggtc
     4741 ttgcaccgcg ccctgctcgc ccgcgcccac accgtcgccg tacggatcca ggcgttcacc
     4801 gacgaccccg ccaacacccc ccatcagctg atcaccggca gccgccgcgc cctggccgac
     4861 ctgacctccc tgcgtacccg ctggcagcac gccaccgcgc cccctccccc tacgaggccg
     4921 cacgcatcgc gcaccccggc ggccacccgg gctgggccgc cacccacaac cgccgcgccc
     4981 gcagcccgag ccacccgatg aaccaccccg ctccggtcgg catgatctat gacacccccg
     5041 gcgaagccat cgcagaattc gagcgcctca acggcgacgc cgtccgcccc ggtcctgcac
     5101 ccgccaccac caccgaactt caagcggcca aggcactggc caccacgtcg tcgggagcaa
     5161 ccacgatccc ctcacacgac acatcgtccg aaccctctcg gtcgaagacg gagaccatcc
     5221 ccgtgtacgc cgcagacccc ggcgaccacg aggcgctgct gagcgacttc ttcgagtgcc
     5281 aggttgggtg ggagaaatgc gcacctagga cgacaacacc accatcgcca cgacgaatcg
     5341 ctcaccctgc gcgtcctctt cgaccacgac gccgaatccc gtgacacgaa atggaccatc
     5401 gccgcctacg aatcccccgt cagcgaccgc atctggcacg ccaccgccac cgcagccacc
     5461 cccgtagaaa tcgtgggcac cccctcctcg acactgtggc ctgcgaagac ccgtgggcca
     5521 ccgggctggg gaccaacgtc acggagaaga ccatcgccga ggccacccgc cccctggccg
     5581 acgccggctg gccgcaaaca atcgaaggac gttggatcca gtggactccg gcggacgaca
     5641 acgccgccgg cgtccagttc gacgccttcg ccgcccagaa acacaacgcc cgctgccgac
     5701 ctggaccatg tagggcggca acaccctcca ccaatccacc tgggccctgc actttcccca
     5761 cacacaccgg ccgggctgct gcaggacatc gccgccgaac tcgcccacgg ccaatccgta
     5821 agacaaactc cccacccacg tcctgccagc aggcaaactt cgccatccgc ccaggcgcct
     5881 gccagctgcc cccctcaccc gccggggtgt tcgagtcgag tgctggatgc atgccttctg
     5941 aagaacgggc ctcgatgcct ctcgccagat cggtggcatc cagcaccgac gcgtcaacat
     6001 ccatcacctc tgccactcgt tggtgttggt ggtgcgagcc cgccgcatgg tgacctcttg
     6061 gtaccccgag ccgtccgagc tcccacgcag accgggcccg tgaggcgcgc tggtgccacg
     6121 aacggctagt gaggtgaagg tacgtccgca acgcggtcga tgcctgggat tagtgcgacg
     6181 cgtggcccgc atgcgctcgt gaccagcgca aaccccagag cgtcgggaag gaattgccct
     6241 gatctactgc ggaatcgacc gggctgaacg cacgcacgac gtcaccctgg tcgacgacac
     6301 cggcatgctg gtggccaagc ggcacatcac ggacgacgct gccggttaca agctgctgct
     6361 ggagctgctc gccgagcacg gcgacaccga ggatagcccg atcccggtgg ccatcgagac
     6421 ttcccgcggc ctgctggtcg ccgtgctgcg gaccgggaag cggaaggtgt acgcgatcaa
     6481 cccgctggcc gccgcacgct accgagaccg ccacagcgtc acgcgcaaga agtccgaccc
     6541 gggcgacgcc ctcgtcctgg caaacatcct gcgcaccgac atacacgccc accggcccct
     6601 gcccgacgac tccgacctcg gccgggcgat cgccgtcctc gcccgagccc agcaggacgc
     6661 gctgtggaat cggcagcaga ccgccaacca gctccgctcc ctgctgcgcg agtactgccc
     6721 cgccgccctg gacgccttcg ctacctggac caacggcctg tgccgccccg aggcacgcga
     6781 actgctcaag accgccccga ccccgacacg ggccaggcga ctgactcgca gccaactcca
     6841 ggccaccctc aagcgcgccg gacgccagcg cggcatcgag gccgaagccg accgcctccg
     6901 cgacgtcttc cgcgccaagg gcgcccacca gccgccgctc gtcgaagacg ccctcggcca
     6961 gcagaggctc accctcctcc tccagctcga cgccgcctgc acggccgccg accagctcgc
     7021 caaggcggtg gaagaagcgt tcccccagca cccggacgcc gagatcctgc tgagcttccc
     7081 cggactcggc atccagctcg ccgcccggat gctcgctgag atcggggacg accgcacccg
     7141 cttcgccgac gcccgcgggc tgaaggcata cgcgggctcc tcgcccatca cccgcgcctc
     7201 cggcaagaag tcgagcatca cgcgccggcg ggtgaagaac gaccgcctca gccacgccgg
     7261 atacccgtgg gccttctccg ctcccaacgg atcgcccggg gccaaggccc actatcgtcg
     7321 gcgccgcgac gagcacggag actggcacgc ggccgccctg cggaacctgt tcaaccgcat
     7381 gctcggacag ctctaccact gccttcaacg acgcgagttg ttcgacgaac gcaccgcttt
     7441 ccccaccgaa ctcgcccatg ccgcttgaca catcggcaac gtgaggtgtc tggcgcatcc
     7501 tcaccaagct ccgcttggaa gctggaagtc cgtcacgcca ccacgctgtt gcgtgcgctc
     7561 ctcgtgctga ccaacctcga agtcacgcgc tgacagacga tcttgacgcc ggacaaccgc
     7621 cccagaccag cacgagaaca cgatcaacgg ctcacaccag ccccgtgacc agcgacttca
     7681 agatggcgga gcttcaatga aggtgatctg gccggcaccg ggcagcagcg gggtgtgcgc
     7741 ggcgagttgg ctgaggaacc tgcggtgcac ggcgtgcaat tgcaaggcat ggccgtgggt
     7801 gaaggagcgc aggaacgttc ccagcgtcga cggggcccgt atcccgccga agagcaacgg
     7861 catggcgccg tgccgccgcc ggtcggcgtc ctcgatgctg tccgcgccgg cacacatcgc
     7921 cgcgatcagc gacgtcacct tggccgccgg gttcgtcctg ccgctgttgt ccgcaccgtc
     7981 gatgcgtacg gtctcgcgga cgagctccga cagctgcccg cgcgcggcga ggcgcatcac
     8041 ggggaccagg ccggtgtgcg cgaccaggtt ggagtcatcg aacgctgcgg acaccgcatg
     8101 tggcgacatg gaagaatgca tcccggagat gcgcctccga actggtcgag tagaaaccta
     8161 gagaactcct attctcccag gtcagagcgc atctccactt tcatgtccag gcactggacc
     8221 gaccgtgacc cggtggatcc gggcttacga cgttgtcggc tattgaagat cggggccgtg
     8281 gccgtgacat gcaggcggcc gcccgggttc ctcgtgtgtg acgacgaagg aatgggccgt
     8341 gcggccttgt cccatcctgc ctttactggt gtctcccgtg cacatctcgg cggtttgatc
     8401 gaggagttgg ctgccccatg gcaggcccgg cgggagtccg agctgcgcga gtggtgtggt
     8461 ggggatcgtc gccgacaggc cggggccggc cgcaagcacg agctggtgtt caccgacccg
     8521 gtgctggtca ccctggccca cctgcgcacc caggctcccg cacgccgcgc tcgccgagct
     8581 gtagggcgtg ggccgttcca ccgtcaccgg ggtcatcggc gcaatccgtc cgctgctggc
     8641 cgaccgcggg ttcgctgccc ctgaccggcc aggagttcgg ctgcggacac tggccgatgc
     8701 gttcgcctac gcggaggcgg agggcgtgaa gctgcggatc gacggcaccg aaacccaagt
     8761 ccgccacccg aaggcccacc gtcctggccg ttgcgcgttc gtctccggga agaagaagca
     8821 gattcccaat ggacttgtca agccggggaa gtggctctcc gtgagggggt catgctgctg
     8881 cggcatctgt ttgaggcgga gcgctctcga aggggcgccc gtcgcgtatg agcgcccaca
     8941 ggacgttgag ccgaagcctg gcgagggcga ggagtgcctg cttgtgtcct ttgccttcgc
     9001 tgcgtttacg gtcgtagaac cgcttggaaa cagggcagct gcgggccgcg acctgagcag
     9061 acaggtagaa gacccgcagc agtcggcgac tgtagcggcg tggtcggtgc aggtttccgc
     9121 tgatacgccc ggagtcccgg ggcacggggg ccagccctgc gacgccggcc aaacggccgg
     9181 aggtgccaaa ggcgtccata gaagccgaag gaggacgccc cgctgggcga gcagtacgcc
     9241 tggcgcgagc ggcggcgcca gtcctccgcg cggatctgcg tcgaacacgc caaccccgaa
     9301 cacaaaaagt ggcgcccact gcaacgcttc ctcggacgcc gcgaacacca ccccgccacc
     9361 caacgggcca tcgccggcct ggtctccgac cgcgccgccc agcggaccac ccgacgcaac
     9421 acgagcaccg aactcgtgcc cgtcagcgtg acggtctgct gtatcaccca ccagccaaac
     9481 ccccaggcca gcacacccga tcttcaatag ccgacgacgt cgttaggccg gaccgcggcg
     9541 gaattgcacc gaacatcaat tcaccagtcg cacacattgc cgcattttgg tgcctcggta
     9601 tgagagtgtc gctcactcac gggaaacagt aaccacttcc ggcatcagcc gttcacggcc
     9661 cggacattga atttgatgcg actgtattta tttcctatgc gggcttgccg catagagcag
     9721 atgcggtgct agtatttcca ttcgatcaag tccctggcat gtgacaggtg attgtgtcga
     9781 tcacgactgc gccgggatca gtgcatgtca attctcggtt cggccagggt gacaggtaca
     9841 ccaaagatca ctgaggagac gtcatgaaga aggcgtacga agccccgacc ctcgtccggc
     9901 tcggcacgtt ccgtaagcgg accggtctct tgcagcgcaa cggcaacgac cgtctgatct
     9961 tcagcaagaa ctaaggcaat cggcgcacgg aatcgacgcc atgcctacgt cgtatgagac
    10021 ggggggagtg ggccccggtg acgcgcactt cgcggtcctt ccggactgcg cggacgcggt
    10081 cgccgcggcc cgctccttcc gccgtccaga agccaggact ctggcgcatc cctcgggccg
    10141 gccgtggctg gtcggccggt ggagcgacca ggaaatcgtt accgcgcacg ccgggtgggc
    10201 cgccatcgcc gtggtgggtt gctgcccggt cggcccggac gaactcaagg ggtacgcaag
    10261 ccggttacgg gacctcaccg aactcgacgc actggcccga aggctctccg gcagcttcca
    10321 cctcgtcgcc gcgctcgacg gacggcagcg cgtgcagggg accgcgtccg gtctgcgcct
    10381 cgtcttccac gcggccgtcg acggcgtgcg ggttgccgcc accagtgccg atgagctcgc
    10441 cgccgcgatc ggcgaggagc cggacgaaga acggctggcc gtacggctgt tgtggccggc
    10501 gccctacccg ctgtcggaga cttcgctctg gcgcggcgtg acggccgtgc cgcccgagga
    10561 cgcgctgatc gtcgcgccgg acgggcggac ggctcggcac tcgcgctggt ggactccgcc
    10621 cgacccggtg cgctccctgg ccgagaacgc gcccctggtg cgggaggcgc tgtcggatgc
    10681 cgtcgatgcc cgtacgagcg cgggcggcgt ggtcagttgc gacctgtccg gcggtctgga
    10741 ctccacctcc gtctgcttcc tggcagcgcg gtcaccggcc catgtggtgg ccagcacctg
    10801 gcccggccgc gaccccgccg actccgacct gtactgggcg cagaaggccg ccggcttcct
    10861 cccggacgtc gagcacgtga tctgggacgc cgacgaatcc ccgctggtgt acgacgacct
    10921 gctggcggtc gacgacctca tcgacgagcc gaccatcggc gtcatggacc ggtcacgcgt
    10981 cctgcaccac ttgccggcgc tggggcaacg aggcagtcgg ctgcatctca ccggcatcgg
    11041 aggcgaccac gtcgcgtggt gctccgaagc ctattaccac cggctcatcc gtacccgccc
    11101 gctgctcgcc ctccggcacc tgcgcggctt ccggaccctg ttccactggc cgctgggcgc
    11161 caccgcgcgc gccctggccg actcccggtc gtacggccag tggctcgcgc acgccggccg
    11221 acagctgcgc gaagcgaagg caccgcccgt cagcgggacc ctcggctggg ggtcaccacc
    11281 gcgcctgttc gactggatca cccccgagac ggcacgcatc gtcgggcggg ccctgcgcga
    11341 cgcggccgag agcgcccaac cgctccaccc cgaccggggc atgcacgccg acctcgagca
    11401 gatccgcgtc tgcacgagga tcgtccggca gtgggaccgg atggccgccc gcgcgggcgt
    11461 gcccatggcc tcaccgttct tcgacgaccg ggtgatcgag gcgtgcctgg ccgtcaaccc
    11521 cgtcgagcgc gtcacgccct gggcgtacaa gcccctgctg accgccgcca tgcggcagat
    11581 cgtgccggac gtgtgcctgg agcgcgccaa caaagcgcag gcgtccatgg acgccaccaa
    11641 cgggttgcgc gaacgacgcg gcgatctcat ggagttgtgg gaggactcgc acctggcccg
    11701 gctcggcctg gtggacggcc gtgcattgat ggagctggcc cggcggccgt ccacacccgg
    11761 tctgaatgag gggaacttgt attcgacgat cgcctgcgaa gtctggctgc gaagcctttc
    11821 gcgtaagagg cgagaggttt ccagcggctg aaagctcaag ggttcgccgg cttacggcag
    11881 aagaggactc cccatatggc actgcgtttc gcctctgaca tcaccactgc ggagaccgat
    11941 tacggcaccg ttctgctcga ccagcggaac ggtcactact gggagctcaa ccccaccggc
    12001 acgctggtgg tccggacact gctcgaaggc ggcgaggaag cggacgccgt cgacgcggtc
    12061 atcgccgagt tcgacatcga ccgctcccag gccacgcaag acgtcgcggc actcatcgag
    12121 tcgctgcgga cctcggggct gaccgcatga cgacaccgag tgcgctgacg cggcctacgg
    12181 gtgtcccgct tgcccggcgg ctggtcgcgc ggctcgtctt catcgccgcc gttcttctgt
    12241 ccttcctgcc cccgcgccgg atccgggcgg tgctcgaagc cgtacgccac ggtgcggcgc
    12301 ccgcctccgc cgcacaggcc aagtccgcac gggacgcgat gtgcgccgtc agccttctgt
    12361 gtgccggccc ccgcggctgc cttccgcgct ccctgggcac cgcgctgctg tgccggctcg
    12421 ggggaacctg gccgacctgg tgcaccgggg tgggcaaggt gcccccgttc atggcacacg
    12481 cctgggtgga gatcgacggc cggctggtgg gcgaaggagt accggacgac tacttcaacc
    12541 gcctgctgac cgtccctccg gtacggcggg cgactcggtg agcgggaagg ccgcggccgc
    12601 gcgtgcggac ggcccgtcgg tgcggggcgc gatcgccgcc atgttccggc tcaccgccgg
    12661 acacaggtcg tcgatgaccg tcgcctcggt gctcaccttg gggggatccg ccctcgggct
    12721 ggcccagccg ctgctcgcca agaccattgt ggacgcgagc gcccacggcc acgtcgtggg
    12781 gcctgtgctg gtcctcgcgg ccctcttcgt cgccgaagcg gcgacgggcg cagtcggccg
    12841 gttcgtcctg gaacgcatgg gagaaagggt cgtccgcggc ctgcgcagca gtctggtcag
    12901 ccggttgctg cgcctggaga tgagggagta cgacaggcac cgcaccggcg atctgatttc
    12961 ccgggtcacc accgacacct ccctcctgcg cgaggtcgtc tcacaagcac tggtggacct
    13021 gatgaccggc tccctcgtcg ccctgggagc cgtggcgctg atgctgtgga tcgacccgct
    13081 gctgctgctc ctggtgacgc tgaccgtcgt cgcggcggtc agcgtgatgg cctcgctgct
    13141 gaccggactg cgcaccgccg ccgagcacat gcaaggagcc atcgggacgg tcgccgccga
    13201 actggaacgg gcgctgggcg cactcccaat ggtgcgggtg caccgggccg aggagcggga
    13261 ggccgagcgg atggggaggt gtatcgacac ggcgtacagc gcaggcgtgc gcaccgcgcg
    13321 actgtcatcc gtgctgagcc ccgcggtcga actcgccgtg cacggctcgt tcctgctcgt
    13381 cctggtcatc ggcggcctac gggtgaacgg gaacgccaac acgctcggcg acctcgtcgc
    13441 cttcatgctc tacgccacct acctggtggt gccgctgtcg tcggtgttcc gggcggtcgg
    13501 cctggtacag cggggcatgg gagccttcca gcgcatcgac gaggcgctcg ccctgcaggc
    13561 ggagcccgcg gaaccggagc cgccggcacg gcaggcgccc gcccgctgct ccccacggcc
    13621 cgccccggcc gcgccggagc ccgccctcgc cctggacgac gtgtggttcg gctaccgccc
    13681 ctgccgcccg gtcctccaag gcatctccct gaccgtgccg cctcgtcggc aggttgccct
    13741 ggtcggcagg tcaggcgccg gaaagagcac gatcttcgcc ctgatcgcgc gcttctacga
    13801 gccggactcc ggcacgctcc ggttcgacgg gcgcccggcg gccgaactgg gccgcaagga
    13861 gtgccgggcg cgcatcgccg tcgtcgacca gaacacccat gtcgtccacg gctcgctctg
    13921 ggacaacatc acttacgcgg cgcccacggc gagcccggcc gaggtccaga gggcggtgga
    13981 actcgccaac ctcaccgacg tggtcaaccg cctgccgggc ggtctggacg gcaccgtggg
    14041 cgaacggggc aacaccctct cggcgggaga acgccaacgc gtggccctcg cacgggccct
    14101 cctcacccgc ccctccctcc tcctcctgga cgagcccacc tcccacctgg acgccatcaa
    14161 cgaagcggca ctcagccacg tgctccagga cgtcacccgc caatgcgccc tcctggtcat
    14221 cgcccaccgc ctctccacgg tccagaacgc cgaccaaatc atcctgctgg aagcaggccg
    14281 cgccatcgcc tcgggccgcc acgaggacct cctgacgacc agtgccgcct accgggaact
    14341 ggcgtcgggg caggcgctgc ggacacaggg cacgaacggg cgcggggcga tgcggcttca
    14401 ctgacctcag agcgggcaca caccttgcgc cactggtgat cttcgtcgct tcgcaccggg
    14461 agaaagaccg catcgccgct cataccccgc ccggtcagcg catcgtgggt tcctgcggtg
    14521 cccacagctc tacagagatc gtgtagctcg gcgccgacgg gacgatcgaa acgcggagac
    14581 ggcgatgatc cgcgctgtac tcatcggcca agtgcagacc acggcccacc tcactgccgc
    14641 gctgggcatg ggcatgcctc tgggcgcctt tcgaaacacc gagccccgtc cttagccgac
    14701 gcgctgggta cctgagggct gtcgcacaca gggcggtcgc ctctcgcgag cgttcgtccc
    14761 ggtgcgaacg ttccgctggc ttacgccact tcgcgtggcc cgatgccaga ccggaccagg
    14821 ttgaacactt ctcgggcggc gtagcgttcc agacagcgga tgatctcgcg ccgggtcttg
    14881 ccctccgcgg tgcgccgctc gtagtagttg cgggtacgcg catcgaaccg gagccgtgac
    14941 tgcacgatcc gatacagggc gccattggct cttcgatcgc caccacggtt gagccgatgg
    15001 cgacgctgac gaccggagga gtactcgacg gggctgaccc cgcaaagcgc cgcgaacgac
    15061 gcctcagtgc gcagacgttc caggttgtcc cccatcgtga tcagcaaggt ggcggcacta
    15121 tccggaccga tacccaccgg gataagcaac tgcggaaagt gacgctcgac cagcccagtc
    15181 aggcgccgct ccaagtcaag aatctgcccg gtcagctgat cgatccgctg agccaacaga
    15241 cacagggcga tgcgggtggc ctgcccgacg gcatccctct caccgtcgtc ccccgcacgc
    15301 tcttcgaact gcgcgcaagt ccggaccagg gctggagcct tcagaccggc cagctgctcg
    15361 cgcaggtccg gatcggcggt gatcaggacc gccttgagct gattgatcgc ctgcgtacgg
    15421 gccttgacag cggagtcctt ggccagtttg aacagacggg cgcactgcac cggcccatcc
    15481 ccagccttgg cctgggagtg agcgcggcca ctaagcaccg accgtgccgc ctcctgcgca
    15541 tccaccggat ccgacttacc acaccgtcga cgaaccgagc gatcaggccg gttcacctcg
    15601 aacacctcga cccggcgagc cagcaagtag cgggagaggg cagctccgta gctgccgggc
    15661 ccttccaccc cagccttgtg caccgtaccc agccggctgg cccactccca gagttcgcga
    15721 tagcccaccg ccgtggcggg aaaggacgcg gtgtccatga ccgcccctag cgtggagagc
    15781 acggcggcca caagagggtt gcggcgtctt gtgtccgctt gatggccgag aggtgcgcgg
    15841 tggcgtcggt gctgggaatg ctggaggagc gggaggcggc tgcccgggta cgggtggagg
    15901 gtctgcggga ggaagccgcg cggctggctg cggtgttgga ggccgcggag atcgagctgg
    15961 accgacgggt gatcgcgcgg gaggaactgg tcgaggccct ggccgcctcc gcggccgagt
    16021 ccactgccgt gaccgaggcc gaggccgagg cggaggcgga gaagggaacc gtgcccgtgt
    16081 cggttccgat gccgggctcg acggtgccgt cctggcggga ggggctgccg gtgacggtgc
    16141 tggcgccgga ctaccaacgg attgtgggcg tgctggatga acaacgatca gcgggcaagg
    16201 gaccggtgaa ggccaaggag gtcgcggtgg agctgggcct tcaggcgacg ccggcgaagg
    16261 tcgaaggggt gcgttcgaag gccagacgtc tggcggagcg cggatggctg ctgcaggaga
    16321 cgtcggggat gttcagtgcc ggccggcggc ccgtggccgc gccagacgcc ggctcatccg
    16381 cgtgaccatc gaccaccgga tcatcgcctc accgcaagcg ggcagagtct cgtaatcacg
    16441 ggccagacgg cgggagttca tcagtcaggc gaacgtgcgc tccgccaccc accgtctcgg
    16501 cattaccacg aaccccgtcg tgtcgtcggt gcgcttgacg atctccaagg tcagagcgag
    16561 tttgtcccgg caccagtcga cgagggagcc ggtgtagccg ccgtcggccc agacgagggt
    16621 gatgtcgcgg tgcagacgac gcagccgcgt cagcaggccc aaggcggcgt cccggtctcc
    16681 gatgttcgcg gcggtgaccg cgacgaccag gagcaggccg aggcagtccg tcacgatgtg
    16741 ccgtttgcgg caacggactt gaacgtgatc tcgacgctgt catcgcgggc ctcaccttgc
    16801 cctggaactc gggaatcgtg gaaggccatg tcaaccggat cattctgtgg aatcagaatt
    16861 gtcaagcttg cggtgctttg ccctgctgga cgtcgacgat cggcaggagg gtcgcgttcg
    16921 gcgggacgtc gaactggcgg ggtgttggcc cggccggggt ggggatgtcg gcgaggcgtc
    16981 ccaggagacg gtcgagggct gcctggccat cgtcgacggc ggcctgctcg tcctcggaca
    17041 gggggatcat cgctcgcatc ttctgcaagt tgcctttacc ttcgagtagt tgggccttgc
    17101 tggagtcctt cggggtgtag aagtcgcagc gtgcgcaggc catgcggtgc gggcattgct
    17161 cgaagaaggt gtaggtgcag tagccatgcc cgaggtcgta gtgctgccag ggttcgccgg
    17221 ccgcggcggc gccagaggtg accgcgtcgc ggtcgaccag gacctcgatc gtgcgaacgt
    17281 tgcgggagaa gtaccccgcg tcgtcgtagg cccgggtcag cgtcgtgggg ctgatcttcg
    17341 cgtagaactg agtggactgc ggtgagctgt gtccgagcca agcctgcagc tcgaacagcg
    17401 tcatcggctc cttcgcgttg tagagctggc tggcgatcgt ggagcgggcc cggtggctgg
    17461 tgatgttccc gcgaacgtct gctgcgggga cgccggcctt gcggcagagc atcgggatca
    17521 cggtgttgtt gatgtagacg gaggagacct tccgggcccg aaaggcgaac agggggtcca
    17581 cgagttcacc ggtgcggcgg tcggtgaact tcggctggac ggggcggacg gcctgccagg
    17641 tatcgagggc ctggcccagg atcggatcga ccggcttggt gaaggcggtg ccggtcttgt
    17701 gggtcggcac gtcgagcagg cagaccgcgt cacgggccag aacctgctgc gagtcgcccg
    17761 cgatcacggt cccgtcgtgc tcccagcgga tgcagccggt ccgcagccgg gctatctcat
    17821 cgctcctctg cccggagaac agccaggtca gcgtgaccgc gcggaccagt tccagagggt
    17881 agaagttccc ggcctgggtc tgcgggaggt cgtcctctgt gaggttcagc ccagcccaca
    17941 tcagcttcgc ccatatgtcg tccgcgatca cgcgcgggtc cgggccaagc agggccgcga
    18001 tgctgcgcgg ggtgcccagt gcgcgctggg gatcgaagcg cctcggtatc cactcccatt
    18061 cctggagatc gcggaagaat gtacggactg cggtgagatg ccccgccttg gacggcgcct
    18121 ccagcggttt gccgaggtga tcctttaggc cagcggtgcg ctggaggtag tcgccgacct
    18181 tcatccggtc caccgcggcg acccaggtcg cgcaggtctt gcgggtccac tcggccggat
    18241 cggcggcctc ggggtgctcg gcctcgatcc accggccgac cttgaagagt gtcgcgcgca
    18301 ggctcccgcg gacccgggtc gtgagcgtgg aggtgtcgta ccaacgctcc acccacgtcg
    18361 cccaggccgg ggagcccccg ctcgcccgcg ccgagtggcg gcccgtcatc cgctgcggcg
    18421 ggtcgcagaa gcccaactcg gcgacggccc gctgcatggc atgcagcgtg ttgccccgtg
    18481 ccgccggcag caggcgctcg gctcggatct gttcgaagag attcgtggtc aagtcctcca
    18541 ggtgcgggct gcggttgagg aggaggacct ggcagaccac catcggcagt agctggtcgt
    18601 cctcgcggcc gagctggtag ccccatctgg cgaggacctt gcggatccgg cggatctcgc
    18661 cgtccacgcg gtcgcggccg aagacgcgcc aggccagcgc gagacgtccg aagctgccca
    18721 gcttgtagaa gtcggcgaag ccgccgagca ggaaggcgtg cacggccagt tggggacgcg
    18781 ccgcctcctc cgcccaggcg ggaacgctcg cgcggaaacc ctgcagatcc ttcccgagca
    18841 gatgggccca ctcctcgccg ctccaggccc agtaggagcg gccggtctcc gcgcaccgca
    18901 gcaggaccac cgcggcggca tccagacgtc cccgccgccg gtgagaggtg gccggctcgt
    18961 gcagtgcggc ggcaacgtcg tccaggggtc gcagcagccg ccgaatcgct ttccagcccg
    19021 gggcgtcagg atcgtgacgg gccatccggc gcaggttgac caggcccagc tccgcgatgg
    19081 cccgcttctc cgcaggccgc accgcagccg cggtgtcata gcggcccggg tcgatcggcc
    19141 atgcccagcg gtcggccaga tccgggttcg tcgagggtga gacgagcgcg gtcaccggcc
    19201 ggcctcccca gcagcgtcat ccctggtgag tgcctggatg cgccaggcgt ggatgtgctc
    19261 catgccgcgg ctgagcttgt cggccagatc gcggccggac aggtggatgt actgcaacgt
    19321 ggagtcggtg tgccggtgcc cggcgaacga ggcaatggca tgcacttccc agcccatccg
    19381 tgccaggtcc gtcaagcaca aatgccgggt ggtatgcgtg gaaaaccgct caacccccga
    19441 ggccagcgca atcctgcgga tcaccttcga ccacgtccac agactgagcg gctgggcgtg
    19501 gttgcggcgc gactccgaca agaacagtgg cccgcgggcg cggctgatcg aggcccggtg
    19561 ggcgaggtag cccgacagca gcaccccggt cgatgccgag tacggcacca cccgctccag
    19621 ccggttcttc gtcgtctccg cccgtatccg cagcgtgcga tgggccggat cgagatcatc
    19681 ggtccgaagt gagcaaagct cctcgcgacg cagagcggcg tcgtaggcca gggcgagcat
    19741 cacacggttg cggaccggct cgtgccgggc cacctccagg atctgcagcc actgctcttc
    19801 gccgggaatc cacggtagct tcgtcaaccg cggcaccagc ccgcgctgct ggccgccgcc
    19861 ttgtcggccc ggggtgtacc gaccacgacc gacagggttg gactcccgca gcccctcctc
    19921 catgaggaag tcgtagaaca ggcgcaccgg caccagccgc tgctggatcg tcgcgttcgc
    19981 cagcccggcc cctgagtcga tcgagatcac gttcacgccc caacgatgcg gccgtgaggt
    20041 caactcgcgt acgtagatcg cgacatgggc acggttcgcc gtgaccggat cgacgtcctc
    20101 gcgctcgcac atcagcaggt actcggccag ccctcggccg taggcgtcaa tcgtgcgcgg
    20161 ggcacgtccg aggtccgtcc aaatcgtcag ccaggccgcc gcctgctcgt gccggccgag
    20221 caccggccac ttctccgtca gcaccgtcgt gccgctcaag ccatctccca agtccgtggt
    20281 tacgccggag agacatgatt accccggcag attccacgta acttttaaag tgatcaggcg
    20341 tcaaatgtac ggccgagctg ggttcgcact tctacggaaa cgcgtcctcc tggcctgatg
    20401 ttgaccacag cgtgtgacca tcacccggct cgcaatcacc cacccaaggt gccgccccct
    20461 cctgacacga tgggtgcgag agcgatgcac ccaaggccgt cgggccgcgc ccggagccga
    20521 atgcagtcaa gccgcagggg cggctgcgcc ggatgccgac cgcgcccgcc gcgcagtccg
    20581 gtgggcatct gcgttttccg catctgaacg gtgagctggt ctgcttcgcc gccgaggacg
    20641 agctttgggt ggcgccgatc gctgcggagg ggcgaggatc ccggacgggc ctggcagctg
    20701 accatagaca gcacccgggt cggtcaaaag gagtctcgcc tgatgtgggg ccactgggag
    20761 ccaaccctct ccccgaaccc tccccaaagc acgcgagatc caccgatccc aatgacctga
    20821 cctgcggaaa caccaaacag gcaggtggcg ttcttgtccg aacctctttc gggacgaaga
    20881 ggtagccggc tcaagtccgc ccgccatgac tgccggctat cggcctcccg acccgcgtga
    20941 gtctggcggc tcccaggccg tgtttgagat gtactcacag cgcctgccgt atcagggcga
    21001 gttggcggtg ggagctgcaa ctgtgcctga agccgctccc actgcgccgt aagatcgtca
    21061 cgagtcatcc cgagatcgct cagccgcctt gatcaacatc ctgcgccatc ggggatgggc
    21121 tcgctgtgcg gctgtcacca ggcgacgggg aggctcgcgg gtttgatgaa gacgaggttg
    21181 tcctcccagg ggatctcgcg ttcggggagg gcgaggaaga gggacgggaa gcgggtgaag
    21241 agggcccggt aggcggtctg caggaagagg cgggccaggg gggcgccgag gcagaagtgg
    21301 gggccggcgc cgaaggtggc cgagccgtcg gtggtgcggt ggatgttgaa gcggaagggg
    21361 ttggggtagt gcgcggggtc gtgggtggct ccgagcatgg ggcagcagac gccctcgcct
    21421 ttgcggatgg tgacgtcgtg cagcgtgacg tctgtggttg cgacccgtgg cattccgagt
    21481 acgccgttgt ggtggtagcg caggatctct tccacggctt tgggccacag gtccggggcc
    21541 gtgatgcact cccggagttg ccgggggttg gtgaggaggg tgacggtgcc ggtgccgaat
    21601 gaggcggtga gtggttcgga tccggtgacg aacaggtacg aggtggtgcc gatcagttcg
    21661 tcttcgctga tgaggccgtc gtagcgggcc aggatcagtg ccccgatggg ttcgttgggg
    21721 tccgggtgcc gtcgtttggt ctcgatgact tctttggtga agtcggtgat ggccgcggtg
    21781 gcctccgcga ctgcctctgc ggatgcggcg aggtgggtct gggtgcggaa gcagctgtgg
    21841 tagaggctgt gcaactcgga tggtacggcg aggatttcac gggccacgtg cagggggagc
    21901 gcgtcggcgt aggcgggcat gaggtcggcc gggttggggc cgtgggccat gtcgtcgagg
    21961 agctgggccg cgtgttgttc gatcatcggc cggtggtgtt cgacggcgct gcgggtgtag
    22021 aagcggctga tcacctggcg gacccgggtg tggtcgggtg ggtcgaggtt gaatatcccg
    22081 cccgggacgg aggtgaagtc gtcgccgacg aagcggggtg ccccggggta ggtgaggttg
    22141 cgggagaagc gcgggtcggt gaggacgtgc gtgatgtcgt ccttgcgggt gaccatccat
    22201 acgcggtcgc cgctgggcag cgcgaccggg cacaccggct gtttcttgcg ggcccaggcc
    22261 aggaccggtg ggggcgtgcc gagctcaccc ggtgggaagg ggtagcgcag cggtaggccg
    22321 gggtcgtcgg tggggtgcgt catgtttggg gctccgttcg ctgtcatgag tggcgggcgg
    22381 gtgaggcggc gggctggggt gccttcacca cggcgtatcc ctgtccgggg gcggggcgga
    22441 gccgggtggt cttgccggtg atgaaggggg cgaggagatc catgtcccgg tggattccgt
    22501 ttcgaagatc gccggtgcgt cgaggacgag gggcagttcg gcgatggcgt agctgacggc
    22561 ctggtcgatc tgctgctcgg tcggctcgtg cccggcggcg tgcagcacgg ccccgcgggc
    22621 ggtgaggcgg catgcacggc gcaccgcttc atcggtccgg taggcatgac gcacgcgctt
    22681 caacgtgtgc tggtaggcgg ggcggttgac cagttgtgtc cagctgtgga agcggagctc
    22741 cgggtcggtg ataccggtgc ggcgcagggc gcgctgggcc gggttgcgca gctgactgac
    22801 ggcgcgccgg gtgcggtgga ccgcttcgcg tggtgggagg ccggccgcgg tcagggtgtg
    22861 ggcggcctcg tatccgggga cgaagacgtc cacggccgcg aagttcgcgc aggcccattc
    22921 caccagggcc tcgacggtgc ggggtttgta gtagccgttc caggggctga gcccgatcag
    22981 tacgtgctcg gcgcggttga ggatgttccg gctgtcgtcg gtgcacggcc gtatgaggaa
    23041 ctccacgtcg gcggtccttt cagcgggtac cgctgccggg ggcgtcgtcc ggccccgcga
    23101 tggcgtcgat gatcagcgcg tgcgggcagg agaggtaatt cgtccagtgg tcgtccccga
    23161 accatctgcg acccgcctcg gacacttcgg gccggatcca gtcgaccgtg gtgaacccgg
    23221 cggtccgcag ggcccgttca tggacgcggg ccgaccaccg gcgggcgtcg acgtcgatca
    23281 cgtggtcgcc gacccgcgct gtcagatgga ccgtggcccc ttcgccgccg ggccggtccg
    23341 tggtgagcgt catgccgtag ctgcggtacc agtcggggtg ggtggcgaag tcggggttga
    23401 gggtcatcgc gacgaaccgc cccccgtggg gacagcgcct gacgggccgt cgcgcacatc
    23461 ccggcgagat cgttctccga cgtcgcgtag gggagtacgt agacggatgt caccaggtcg
    23521 aaggcgccgg cgagaccgtc gtcgagggag cgcgtggcgt tgtggtgcac gtacgtgatg
    23581 ccgtgtcgct cctgctcctc cttgcggcgg gcgtattcga tcatggactg cgacgtatcc
    23641 atgccgacca cccgcttggc acccaaggca cggaagcgcc gcgcatacag gcccgtaccg
    23701 cagccgaggt cgagcacggc aagccccgtc agactgccga tggccttcaa caggctgtac
    23761 gcctcgacgt gctcacggaa cggcaaccgg ttcatgctct gctcgtacgc ggcaacgatg
    23821 gaatcgaact gactgtccaa gacgctctcc tggtcattcg tcggatggag cgatgcgcca
    23881 caggtccctc cgtagggccg gaaggaacag gctcgcagga ctcaggaaag cgtgatccgt
    23941 gccgcgtctc cacggactcg aatgtgccta aggcatgcct tgccccgctc cacggactcg
    24001 gatgtgccta aggcgtgcct tgccccgctc tgctggtgcg gggacccgaa agagctctct
    24061 acgattcggt tatctttcaa ttacccacga gggtgatatg taccagaggc caggtaaatc
    24121 cgggattgtg cggcacccgt tgaaggcggc acgggaatcg ctcggcctct cccagaccgc
    24181 gtacgcacgg ctgatcgcca aagcccacaa cgaactcggc tttggcccca aaatggtcaa
    24241 gacccactac acggtcttgc actgggagtc cgggcggaac gaacccgagc ccaacacaca
    24301 actcgccatc gcacacatcc acggggtgaa cctggaggac gtgctgcgcc tcggctggcc
    24361 ccactggctg cacctggcca ccgacgacgc cacactgctg aaccagtcgt ggacccccca
    24421 gagcgccatc gatgccctgc acagcaccgc gcgcctcgcc gatacgagac cccgctccta
    24481 cctcgccgtc accggccccg ccctcgactc ccagatcagg gcgacgcttg ccgccctggc
    24541 cgacccgcag ccgccacctt cccgcgaggg acgccgcgtc acccccgaca cgctgacccg
    24601 tatcgaagcc cgtatcgaag cactggaact gcaggaggca agggcattga ccacaccgat
    24661 ggccctgtac ttcgccaccc gcgcagaaca ccggctgctc accacactcc tgaccagcag
    24721 cggctacgac cacaaagccg gggcccggct gctgctcctc gccgcgcgca ccgccgcgct
    24781 gtgcgcatgg ctcagtgggt gcctgggaga ggacgccagg gcagaacggt acgccctggc
    24841 ggcgatccgc gccgccagcg tcgcaggcgc gcgacggcac gttgccgcgt atatgcccga
    24901 cctggcattc cgtcatctcg tagccggcga cccgaaggac gtgttgtcct tggttcatgc
    24961 cacacgggcg atcgtccggc acccctcgcc cggcctcgcg gtcaccctgc acagcaggga
    25021 ggcccaagcc ctcgcccgcc tcggggacat caccgccagc acccgggcgc tggatcgagc
    25081 cgtcagcaca ctggtcaccg ggccgaccga ggtggaccct acgatcgacc cgctttccat
    25141 caacgtcgac gaggaatggc ttgacgtctc ctccggggcc gcctggcttc atctgggccg
    25201 gcccgagaag gcactgccgc acttgaccac actgctcgac gacggccccc cttcgcgccc
    25261 gcccacccct ccctccccat gcgcagccag ccgcctccta tatgtggtcg acgcacagct
    25321 ggccctcggc gaactcgacg ccgccaccca cagcgcccac cgcgccgccg ccctcgtcgg
    25381 taacctgccc cctgacctcg cccaccagtt ccggcaacga ttcgcccccc acaccaccga
    25441 acccgccgtg cgagacctca tcgacaccct gaccgaacac cccacacact gaccccggca
    25501 tggagaaatc cgctctccac ccagcccacc ccacccagcc ggcgacacca tcggcaaacc
    25561 gaaggcggcg cgaggtgttg atcaaggtct tggaacgatc tcgggttggc tcaggcgaac
    25621 tgacggcagc acagcgagag cagcttaagg tgctgttgcc accgatgccg cggatcgggc
    25681 gcccgccccg gactggccgc agcacctacg cccgtctgta cggccacgcg gccgcgcccc
    25741 agcaggcggc cgggcatgag cgcgtggccc gccgtacgcg atacccggcg cgcggcaccg
    25801 tctccaccac cgccggctcc ccgagccttg accgcagccg gctgaccgag atccgtacgg
    25861 cattgccgcc ggcgcccagg tccccgcctc acacctgcgc catcagctcc tcggcggact
    25921 ccttgcccgc gcccttgatc cggcaggggt tccggcggat cagctcgtca tcggccgcga
    25981 tttccatgat ggcgctcagc agccggtacg acttggcgac ggtggtcgcg cccttcctgg
    26041 cgctgctgcg cccggacagc gtctccagcc gctcgacacg gtcttggtcg cgaaggtctc
    26101 cggcgaacgg cggcgcagac ccgtggggtt cacatagctc gccgtccagc gcccggacgc
    26161 gggcgaagcg gctcacggag cggctgggcc ctgaagcagg gcgaagggcg agaagcggag
    26221 ggcgtcagcg atggcgacga ggtcgtcggc gtcacagcag cgctgggcgc gctcgatgcg
    26281 ggacagcatc gtgttggaca tcggtcggcc gagtccggtg acgcgatcgg ccaactgacg
    26341 ctgcgcgaga ccgcattcgg tgcggacaat ttcgatagtg cgggcggtcc gcattcctgc
    26401 cggaccgatt tccagggatc aggctgccat gactcagttt tagctttcgg tcgcgggttt
    26461 cggtaaccgg gctttgtcgg ctatatatcg cccagcacgg tggccaagca ggcatccgac
    26521 gcgggcatgc gggtctcgga cgagattgcc gtccagtttt cgaaatggcc ttctgacctg
    26581 gtgtgttgtg ttgtagcttg caccgcggcg ggcggtcaac agtttcccga tgtgatcctt
    26641 ctggctcggc cactgggcgg ctgatttcgg caaccggggg tccgggtcta ctgttttgag
    26701 actgtcgcgc agagcccgtt cgccgtgagc tgtttgcttt ctcggcggaa tgctggactt
    26761 gcacgggcgc gtgtgacttt ctttgccata cgcgcaggaa cacccgtgcc gaggacatgg
    26821 aaaccgcggc atgccaatgc aggggccaag gagtcccgcg cggcatcgcc cgtgtcccac
    26881 gaaccggacc catggtcgtc ccgactgccc ctgctcacac ccgcggccct caccaagacc
    26941 cttgacgtcg cgccagtccg gggcaaaact tccgttcacc ggtcggcatt gccgaacact
    27001 taccggcaat acgcgatgag tgtggcaatg ccaagggccg gcaacgccct cacctgaggg
    27061 cgcggaccac cggaggggac ccgggtgttc cctggcatca cccactgcca cggtgccgcg
    27121 tccggcccgg ccgatcgaaa tccgatgggt cctcagggcc gttcccgcat atcccgctgc
    27181 ctccgcgcct gtcgtactcc cccttcacga ggacctgatg acacaacaca taccggaggc
    27241 ggtgttctgg tgcctcgccg cggtcacgct cgccggagtg tcgctgctgg tacgccagta
    27301 ccggatcacc gccgccctgc gccgtcgact gacgatccac gaagccggcc tgctcgcccg
    27361 ggaggaggag gtccggcacc tctccgaggt tcggcttccc gcactggtcg aggcggccca
    27421 cggcagcgca cccgtgcccg ggcctctcga tgcggatctc gccggaacga cgtacggaaa
    27481 gaacctgcag cagatcgtcg agcagttcac cggggccgcc gaggccacgc gatcccgggc
    27541 ggacaggtcg gcgaaggcga cactgaagtc ggcgatgcgc gccctgcagg cattggcgaa
    27601 cgagcagcag gtgtcgatct ccgacatgca ggaccggcac gacgaccccg atgtgctccg
    27661 ggacctcctg gagatcgatc atgcaaatgc gcagttcggc cggaggacgc aggccatcgc
    27721 catgctctgc ggctcgtggc ccggacggca gcggaccgcg tcaccgctgc tcgacgtcgt
    27781 acgcggtgcg acatcgagga ttcgggacta ccgacgcgtc aaggtgcact cgcgcgtcga
    27841 catggacgtc gtgagccgag ccgtcgagcc ggtcgtcctc gcggtcgccg agctgctgga
    27901 caacgcggcg cggcactccc gacccaacac cactgtcgaa gtcggcatcc agcccgccca
    27961 caacggcgtc agcatcgtcg tcgacgacgc cggcatcggc atggacgcgc gcgaaaccga
    28021 ggaagccggc cggcgtctgt ccggcctggt ggacatcgac atcaacaagc tcggcagccc
    28081 gccgcagttc ggcttcgccg tcatcggcgc actcgccgcc cggtacggat tcagcgtctc
    28141 ggtcaacacg cagtccccgt acggcggtgt gcgggccgtg ctctttctcc ctaacgcgct
    28201 cctcaaccgg gtacgtttca tgggcccgcc gatccccgcg ctgggagccg agacaccgcc
    28261 cgccccggag ccggcctcac ccggcgcgtc cgaagaggca gcgccgtcgt ccaccgcggg
    28321 tggtctgccc aagcgccgcc gatgcacgca gcagcaccag gcagccgacg gcggccccga
    28381 ggccccggcc tccactcccg cgctggtccg ccccgccgcc gagaccgcct cccgtatggg
    28441 cgcgttcgcc cgcggcaccc gctccggccg cgactcctcc cccgacaccg aaggaacccc
    28501 ccaggaatga ccggccagat gaccaacgaa ctcggatgga tgctcgacga ggtcctgaag
    28561 gtcccggaag cccgccacgc gatcctgctc tccgcggacg gcatgctccg cgcccactcc
    28621 cagggcatca agcgcgacga ggccgagcgg caggccgcgg cgttgtccgg actgcagtcc
    28681 atcagtcgca gtaccgccga gttctgcggg ctggagacct cgccgtggca gcagacactg
    28741 gtcgagttcg ccgacgggta cgtcttcctg gtggccgccg gcacgggcgc gtatctggcg
    28801 gtctcggccg gccaggacgt cgacatggaa gccgtcacct acagcatgca caagttggtc
    28861 gaccggctgg gcaaggagct gaccagtctg ccgcggcagc attccgtacc cggcaggccg
    28921 gacgactccg gtacggcatg accccgccgc gccccccgca cgacagagga ctcgtacggc
    28981 cgtacgtcgt cacggagggc cgcgcccatc cgacgcgcaa cacactggac gttgtggcgc
    29041 tggtgacggc cgtgcacgac cgtcccctga aggggctgag cccggagaag cggcgtgtga
    29101 tcgaactgtg ccgacccggg gcgctgtcgg tcgccgaagt ggccgggcat ctcactctgc
    29161 cgatgagcgt caccaaggtc ctgctcagcg acctcgtcga cagcggccat gtccacgtcc
    29221 ggcctcccgt ccccaaggca caactgcccg acgcccgatt cctgcaggag gtgctggatg
    29281 ggctccgctc ccgtttctga cccggtcgac ccgatctacg tctcggacac ggtcacgacc
    29341 gcgatcaaga tcctcgtcgt cggccacttc gccgtcggca agaccacgtt cgtcggcacc
    29401 ctctccgaga tccggccgct gcgcaccgaa gagaccatga cgcaggccgg cgagctcgtc
    29461 gacgacctcg cgggcgtccc cgacaagacc acgacgaccg tggccatgga cttcggccgc
    29521 ctcacgctca acgagtccct ggtgctgtat ctcttcggcg cccccgggca gaagcgcttc
    29581 acccagctgt ggaaggacat gctgaacgga gctctcggcg cacttgtgct gacggacacc
    29641 cgaaggctcg accagtcgtt cgacatcatg ggcctgctgg aagagcacgg catgccgtac
    29701 gcggtcgccg tcaaccagtt cgacggcgcg ccggtgttcc ccgaggcgga gatccgcgag
    29761 gctctcgacc tgctgccgga aacccccctg gtcacctgcg acgcgcggga agccacgtcc
    29821 ggtgccggag cgctgatctc cctcatcgag tacctccaga cccgcacccc tcaggagcaa
    29881 gaatgacgac accccggccc gcacaccacg cggcgcctcc tctcgactgc ccggcgcacg
    29941 ccggcgcacg tacggtggag cggctgtacg gcccggagtt cgccgccgac cccatggcgt
    30001 cgtacacccg actgcgcgcc cacggctccg tcgcgcccgt ggagatagcg cccggcgtgc
    30061 gcgcttctct ggtcatcggc tacgacaccg ctctggaggt actgcgcagt ccggagcgct
    30121 tctccaagga cccgcgccgc tggcgggctc tcgccgacgg gacggtgccg gcggacagcc
    30181 cggtcgtgcc gatgatggcg taccggccga acgccctgtg gaccgacggc gacgaccaca
    30241 gccgactgcg tggcgccatc accgacagcc tgggccgcgt ggaccccgac gcgctcatgc
    30301 gccacgtgga gcacagcgcc gacaccctca tcgaccggat cggccccaag gggcgggcgg
    30361 atctcctcca cgagtacggt gctgtcctgc ccctgctggt cttcaacgag ctcttcggct
    30421 gcccgcccgc caccggggac aagctggtcg agggcatgtc cgggatcttc gacgccgacg
    30481 ccggctccga gaaggcgaac gcggtgctgg ccgagggcgt cgccgagctg gtggcactca
    30541 agcgggcaga accggggccc gacgtgacgt cctggctgat ggcccatccc gccgggctga
    30601 ccgacgagga gatgtcgcac cagctggtgg tgctcctggg cgtgggcacc gagccccagc
    30661 tgaacctgat ctgcaacggc ctgcggctgc tgctgtccga cgaccggttc gccggtgatc
    30721 tcgcacgcgg caccatgccc gtcgaggacg ccatcgacga ggtgctgtgg accgacccgc
    30781 cgatggcgaa ttacgccgtc cactatccga tccacgacca ggaactcgac ggaaccctcg
    30841 tgtgcgaggg tgagcccatc ctcatcagcc tggccgccgc gaacaccgac ccgggcctca
    30901 gcggcgaacg ccggaccggc aaccgcgcgc acctcgcgtg gagcgcgggc ccgcacacct
    30961 gtccggcgaa gggcccggcc cgggtgatcg ccgcggtcgc cctggagaag ctcctcgacc
    31021 ggctccccaa catcgaactg gaaatcccgg tcgagaagtt ggaatggcgg cagggcccct
    31081 tccaccgggc tctggccggc ctgcccgtcc gcttcccacc gatcagccgg cgggtctgac
    31141 ggtctccggt gtgacgacgt ggtcggcaat tgagataggg gtgtgtcggc ctggcggttc
    31201 ggctggcggg tgatcagcgg gaaacccggt gggcgagtac cggttcggtg ctcggcttgc
    31261 ggacagtggc cctgcgggcg gcgcggtcgg agaccagacc ggcgacggct cggtggattt
    31321 ccgcgtaggt ttcgcggcgg gcggtaaacc gctggagcgg acgccagtgc cggtgcccgg
    31381 cgttggcgtg ttccacgcgg atccgggcgg cggggcggcc atgccaccgc gggcgcggtc
    31441 ctggtcggcc ccgacggccg catcctgcac atccaccacc tcgccaccgg caagtggctg
    31501 ctgcccggcg gccacctcga accggaggac aacacccacc tgcaggccgc cggccgcaag
    31561 ctcaccgagg agaccggtat tcctacccac gtgctcacgc cgcacggcga gaccccgctg
    31621 caacatcgac gtccacccca ttgacgccaa ccccgccaag cacgagcccg cccaccagca
    31681 cttcgatttc cgctttccct tccacaccac cgccgacatc ggagaactcc agaccgaaga
    31741 ggtctccgac gccgcctggc gcgagatcga caccatcagc gacgcgcccc tgcggcagca
    31801 catcgccgag gccctgctca acccgacagc gacgccgcga tgaccggcca gccgccccct
    31861 tgccgagccc tggccgatca cgggcgagcg agagcggcag ggacagacag ggacacgcct
    31921 gatccactta ggcagtgtcc tggcgatcaa tccacaccct cagccagcgg ggggcggtgt
    31981 tggggtggca gcagaggcgg ccctgaggat ggatgtgccc agggtcgcga tgggacggcg
    32041 gggccacagt cggcgcaaag tggtctgggc cgtgaggcgc agaggcggct ctgtggggag
    32101 ccaatactgt ccagcggttt ctgtgtggcg tttgcgagct ggttcctgtt ccgtcgtaga
    32161 ccgcaaccgg cgcgtaccgc cggtgaggcc gcagcgtggc ctgtctgggc agggaacgat
    32221 cttcgtgagc cacaagcgca ccgtggcatc aaggtcctgg gtacccggat ggcgcagggt
    32281 cggtggtcgc gggttccgaa ggctgcatcc cgcttacggt gttcctggag ttggggtggg
    32341 ggtgtccggg ttatcggtgt gccccggttc ggtgcgtacg gacgagatgc cgatcgcgag
    32401 gcagcccgat gaggtgcctg cgatgagcat gccgtggcat gcagccagtg cgtgaacttt
    32461 tgtcgccagg ggcagtgtgt gccctgttcg tgattgcggg ttccagatcc gtaccgtctc
    32521 gtcgccgccg ccggtggcca ggcgcgggtt gccgtcggcc gcggtgaacg ccgccaccgc
    32581 ccgcaccgcg cggtggtggc cggtgagggg ttcgccgatc tgggtaccgg tggccgggtc
    32641 ccagatccgc accgtcccgt cgtcgctgcc ggtggccagg cggaccgtgc cgtccgctgc
    32701 ggtgaacacc gccaccgccc gcaccgcgcc actgtggccg gtgaggggtt cgccgatctg
    32761 ggtaccggtg gccgggtccc agatccgcac cgtcccgtcg tcgcctccgg tggccaggcg
    32821 gaccgtgccg tcggccgcgg tgaacaccgc caccgcccgc accgcgccac tgtggccggt
    32881 gaggggttcg ccgatctggg taccggtggc cgggtcccag atccgcaccg tcccgtcgcc
    32941 gccgccggtg gccaggcgcg ggttgccgtc ggtcgcggtg aacgccgcca ccgcccgcac
    33001 cgcgcggtgg tggccggtga ggggttcgcc gatctgggtg ccggtg
//
