LOCUS       NZ_CP086322            20609 bp    DNA     linear   CON 26-NOV-2024
DEFINITION  Streptomyces halobius strain 3_2 chromosome, complete genome.
ACCESSION   NZ_CP086322
VERSION     NZ_CP086322.1
KEYWORDS    RefSeq.
SOURCE      Streptomyces halobius
  ORGANISM  Streptomyces halobius
            Bacteria; Bacillati; Actinomycetota; Actinomycetes;
            Kitasatosporales; Streptomycetaceae; Streptomyces.
REFERENCE   1  (bases 1 to 9239126)
  AUTHORS   Wen,Y., Zhang,W. and Liu,X.G.
  TITLE     Streptomyces nigrumlapis sp.nov.,an antimicrobial producing
            actinobacterium isolated from Black Gobi rocks
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 9239126)
  AUTHORS   Zhang,W., Liu,X.G. and Wen,Y.
  TITLE     Direct Submission
  JOURNAL   Submitted (04-OCT-2021) Northwest Institute of Eco-Environment and
            Resources, CAS, Chinese Academy of Sciences, Donggang West Road 320,
            Lanzhou, Gansu 730000, China
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method :: GS De Novo Assembler v. FEB-2021
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 241.26X
            Sequencing Technology             :: PacBio Sequel
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_023277745.1-RS_2024_11_26
            Annotation Date                   :: 11/26/2024 03:43:17
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.9
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 8,438
            CDSs (total)                      :: 8,346
            Genes (coding)                    :: 7,837
            CDSs (with protein)               :: 7,837
            Genes (RNA)                       :: 92
            rRNAs                             :: 6, 6, 6 (5S, 16S, 23S)
            complete rRNAs                    :: 6, 6, 6 (5S, 16S, 23S)
            tRNAs                             :: 71
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 509
            CDSs (without protein)            :: 509
            Pseudo Genes (ambiguous residues) :: 0 of 509
            Pseudo Genes (frameshifted)       :: 193 of 509
            Pseudo Genes (incomplete)         :: 418 of 509
            Pseudo Genes (internal stop)      :: 17 of 509
            Pseudo Genes (multiple problems)  :: 113 of 509
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 18:33:41
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 1897487
            Orig. end                         :: 1918096
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP086322.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            This genome has a base modification file available.
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..20609
                     /candidate_cluster_numbers="1"
                     /candidate_cluster_numbers="2"
                     /contig_edge="False"
                     /product="terpene"
                     /product="RiPP-like"
                     /region_number="15"
                     /rules="(PT_phytoene_like or phytoene_synt or Lycopene_cycl
                     or Lycopene_cycl_fung or T1TS or T1TS_KS or T2TS or TS_UbiA
                     or TS_Pyr4)"
                     /rules="(strepbact or Antimicrobial14 or Bacteriocin_IId or
                     BacteriocIIc_cy or Bacteriocin_II or Bacteriocin_IIi or
                     Lactococcin or Antimicrobial17 or Lactococcin_972 or
                     Bacteriocin_IIc or LcnG-beta or Cloacin or Linocin_M18 or
                     TIGR03651 or TIGR03693 or TIGR03601 or TIGR03795 or
                     TIGR03975 or DUF692 or TIGR01193 or (YcaO or TIGR03604))"
                     /tool="antismash"
     cand_cluster    1..20609
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /detection_rules="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193 or (YcaO or
                     TIGR03604))"
                     /kind="neighbouring"
                     /product="terpene"
                     /product="RiPP-like"
                     /protoclusters="1"
                     /protoclusters="2"
                     /tool="antismash"
     protocluster    1..20609
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:10609](-)"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..10609)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
     gene            365..760
                     /locus_tag="K9S39_RS08990"
                     /old_locus_tag="K9S39_09060"
     CDS             365..760
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020117286.1"
                     /locus_tag="K9S39_RS08990"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="K9S39_09060"
                     /product="PadR family transcriptional regulator"
                     /protein_id="WP_248862793.1"
                     /transl_table=11
                     /translation="MASKPLTEAVFFVLLALLDEPRHGYGIKQEAAALSDQRVDLRVGT
                     LYGVLDRLTAEGLVEHDRNEVHQGRLRRYYRLTGDGTRALEAEKARMAANVRVAEQRLT
                     GSGSDVDAPAAPKSRGRARPAGAGGIA"
     gene            757..1902
                     /locus_tag="K9S39_RS08995"
                     /old_locus_tag="K9S39_09065"
     CDS             757..1902
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="K9S39_RS08995"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="K9S39_09065"
                     /product="hypothetical protein"
                     /protein_id="WP_248862794.1"
                     /transl_table=11
                     /translation="MNTSDTLLEARFRAVLRVLPAYYRQEREEEMVDTFLSDHEPLDED
                     TALGRPGPREVAGVLVLAVRTRLAGPGAPARYVAYGHTARLVGLFGVALLAASTAVSLL
                     AEVAVLLAGSAQERQLVLGAFVGRSQGSTPDAFTTGWALMVELLPLGWIAAAVALGTGH
                     RRRAAVFCAAAAVPTFVDLGQSARLGFLPSASSLAAIALVVAVTASVTMAFHPAAPRVE
                     VSRLTSEWIPVGCFLILLAAVVAGRLVLGFDDGSYGWAFLVGGVVCLVLRVRNRDRHPD
                     APPLHGADPRALASGPALPAALATLGLPVLTMRLDAAALFTSTPGVPAEALVTNVAQSV
                     AVAILEATLLVVAVRALRRESRTWPSSTAVSDYSCAPGSHP"
     cand_cluster    807..11748
                     /candidate_cluster_number="2"
                     /contig_edge="False"
                     /detection_rules="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193 or (YcaO or
                     TIGR03604))"
                     /kind="single"
                     /product="RiPP-like"
                     /protoclusters="2"
                     /tool="antismash"
     protocluster    807..11748
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[5806:6748](+)"
                     /cutoff="20000"
                     /detection_rule="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193 or (YcaO or
                     TIGR03604))"
                     /neighbourhood="5000"
                     /product="RiPP-like"
                     /protocluster_number="2"
                     /tool="antismash"
     proto_core      5807..6748
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193 or (YcaO or
                     TIGR03604))"
                     /neighbourhood="5000"
                     /product="RiPP-like"
                     /protocluster_number="2"
     gene            complement(2126..2887)
                     /locus_tag="K9S39_RS09000"
                     /old_locus_tag="K9S39_09070"
     CDS             complement(2126..2887)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018541003.1"
                     /locus_tag="K9S39_RS09000"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="K9S39_09070"
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="WP_248862795.1"
                     /transl_table=11
                     /translation="MQATTLVHRMEDLFDQGLESQAGAALLRFGAARQRQDDRIGWSGD
                     GAAAWFDDARGHVWSVGEPEAAAGLVLRAAHVLPGQVREFTGPRRTDVLVGRHLAVTDV
                     VEWVFRWTLEEPPVHRAEERVVELDEAHHEELLAFLNEHSPDHSTGPGSSDVTLWVGIR
                     DADGRLVACGALSSLRDSGAPLMASVATDAGLRGQGLGAALTSWLTRHAIRQHGFCTLW
                     QLADNSPAERLYTRLGYRNEDPCVAARIATR"
     misc_feature    complement(2844..2859)
                     /note="TFBS match to LexA_variant_1, Repressor of DNA
                     damage response, confidence: weak, score: 20.27"
                     /tool="antismash"
     gene            3670..4962
                     /locus_tag="K9S39_RS09005"
                     /old_locus_tag="K9S39_09075"
     CDS             3670..4962
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF014696.5"
                     /locus_tag="K9S39_RS09005"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="K9S39_09075"
                     /product="phosphatidylserine decarboxylase family protein"
                     /protein_id="WP_248862796.1"
                     /transl_table=11
                     /translation="MTRDTPHLWTEQKLDARYENLFGRAAGYLPENRAALDAWLDDFSR
                     DVHERRARNAIVRHPSVADLARLIERDRIVRMYVSRMINEAHQRDCKNTVNDIPDLLDH
                     LDCIVTSTPKYQGPTAFPMSALFTYLMMTTDGYAVFRDQGFNKALLGILREWCAHLDSK
                     DSQEVLNQKNGWLSPAALADKKLNLQDFQINLQDPYGGFPSFNAFFHRELRKDKDVRPI
                     DDPDDPRIIVSANDGKVVRIRRDIKRSDEFWAKGQRYSLYDMLDGSDLTDLFVGGDVFQ
                     SFLSGGDYHRWHAPVSGVVRSARVVEALMFTELEHTSGRDAGTESQVYGASVNTRGLVF
                     IECPPPIGMVCVMPLGMTEISSVTLTVQPGDQVTKGQEMGYFSYGGSSMCLLFQKGAIE
                     KFFPKDNTGDMEEGDPIKVNARIAQAVGDEA"
     misc_feature    complement(3698..3713)
                     /note="TFBS match to LexA_variant_1, Repressor of DNA
                     damage response, confidence: weak, score: 22.69"
                     /tool="antismash"
     gene            5079..5852
                     /locus_tag="K9S39_RS09010"
                     /old_locus_tag="K9S39_09080"
     CDS             5079..5852
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="K9S39_RS09010"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="K9S39_09080"
                     /product="hypothetical protein"
                     /protein_id="WP_248862797.1"
                     /transl_table=11
                     /translation="MGLNACAGQDVGGKATMAGTGQCATVQHVCHGEGACRGQGGCGYA
                     GDDFEQFHPGEQSCRYNGSCASPINESRVFSAGPLKGRSVWQQARRLFEARMYAAGKAF
                     GPSPGQGVPDDRFPDYDRLEPGHTPVPGSSDEATALFRASADNPRRHEGKAFPDLQAIA
                     RNGIGRHLPNVSITFTIPPSASSLLYFQRDGEAKTSSCTVATGATGVATALPLYAGHTS
                     PNDQWVTVTATGPVYANGSATCEFHVTVLAPEEQQ"
     gene            5807..6748
                     /locus_tag="K9S39_RS09015"
                     /old_locus_tag="K9S39_09085"
     CDS             5807..6748
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RiPP-like: DUF692"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF003818.1"
                     /locus_tag="K9S39_RS09015"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="K9S39_09085"
                     /product="DUF692 domain-containing protein"
                     /protein_id="WP_248862798.1"
                     /sec_met_domain="DUF692 (E-value: 5.8e-97, bitscore: 323.0,
                     seeds: 7, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRIPCHGPGARGAAIAPGEAAGTATRTGSAAQRTTPDLGFGLGLR
                     GPHIPYIREHRPPVDFFEIISENYLKPRTARRRALDEIAERYPIVLHGVSLSIGSTDPL
                     DLDYLRHLKRLADAVDTPWVSDHVCWTGVLGVHTHDLLPLPFTEESLRHVIQRARTVQD
                     MLERPLLLENPSSYLQFRASTLTEWEFLGRLAEDADCGLLLDVNNVYVSAVNHGFDPET
                     YLKALPHHRVAQMHLAGHTDYGTHLIDTHDADVPNPVWELYRLAVELTGGAAATLIERD
                     DGLPPFPVLRAELDTARAVAAAAIGQEGGGDD"
     gene            6741..7490
                     /locus_tag="K9S39_RS09020"
                     /old_locus_tag="K9S39_09090"
     CDS             6741..7490
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF021364.5"
                     /locus_tag="K9S39_RS09020"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="K9S39_09090"
                     /product="DNA-binding domain-containing protein"
                     /protein_id="WP_248862799.1"
                     /transl_table=11
                     /translation="MTDVPCSLAAIQRWMQGALLAPGGAAQATEGAQTAQVAEVVAAPG
                     RLTAEECFGIYYRGYRLRLLRCMRDQYPGMVRLLGRELFDRFALDYVDAHPSRSPSLDG
                     LGAGFPGHLARTRPDAASDGAPREEWIDLLIDLARYERDFAAVLDGPEADGGAAPWTEP
                     EPGSGADPGSGSGAGPNSGSGTRLFEAQFPVHRYAAAVRRGEDPEPPTAEPVFLALSCQ
                     NGTVVVHDRAESRYRTRQTAHRPSPAA"
     gene            7512..8792
                     /locus_tag="K9S39_RS09025"
                     /old_locus_tag="K9S39_09095"
     CDS             7512..8792
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF024306.5"
                     /locus_tag="K9S39_RS09025"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="K9S39_09095"
                     /product="ferritin-like protein"
                     /protein_id="WP_248862800.1"
                     /transl_table=11
                     /translation="MPHLTTPLAVRAIDGITTRDELADHLGDAARIELSTIPPYPYAAY
                     SLKTPGYSQRAQGASAQRTLIGIAIEEMLHMALVRNVMVATGCETVKTKDGNQRKASRF
                     YDKDSIPTYPGDMSHRTPPLPLHLQRISTAAVEGFMEVELPETAQQQLLTSADDYSYQT
                     LGELYDAIGKGIVHLTGTKDITWGLTESRWQQQYLRAFWNQWGGPPKPIPVVDQGSALD
                     ALYIIVSQGEGAPDEQEESHYEKFTRIRDHVDGIGVVCDDSGRQKYTIDSGDEAVWPVV
                     TDPNASDFTGSLKQLALLSDAAYCYVLALLDKLYLTPADDPDSGPGQGEPHPTSKRYAL
                     ERGFIAAMQGVLSPVANILVSTPLTDGPNAGRHAGPTFGHYDFQGVPPRQALLDLCTDK
                     DLATDFPQLGGSDGVLNQIRLLPDFTI"
     gene            <8882..>9103
                     /locus_tag="K9S39_RS42915"
                     /old_locus_tag="K9S39_09100"
                     /pseudo=""
     CDS             8882..>9103
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF024002.5"
                     /locus_tag="K9S39_RS42915"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /old_locus_tag="K9S39_09100"
                     /product="phophatidylserine decarboxylase associated
                     domain-containing protein"
                     /pseudo=""
                     /transl_table=11
                     /translation="MVTWAPAFDRDPRKQIFLPMSALFGYLRLTPAGAVAFRLPQFNDG
                     LRAILQRWCTYLNSPESAHVLNTRDWFSQ"
     gene            9139..>9492
                     /locus_tag="K9S39_RS42920"
                     /pseudo=""
     CDS             9139..>9492
                     /GO_function="GO:0004609 - phosphatidylserine decarboxylase
                     activity [Evidence IEA]"
                     /GO_process="GO:0008654 - phospholipid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF014696.5"
                     /locus_tag="K9S39_RS42920"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /product="phosphatidylserine decarboxylase"
                     /pseudo=""
                     /transl_table=11
                     /translation="MLGLPRPGALGLLVVQRILPPPDQGRVPAAGGPRRPRAVVAPNDG
                     TVHQIRRNVARQADFWLKEQYSLETMLSGPECGAEYVSRFVRGDVYQSFLSVNSFHRWN
                     VPVDGTIKHLEIVP"
     gene            <9557..9868
                     /locus_tag="K9S39_RS42035"
                     /pseudo=""
     CDS             <9557..9868
                     /GO_function="GO:0004609 - phosphatidylserine decarboxylase
                     activity [Evidence IEA]"
                     /GO_process="GO:0008654 - phospholipid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF014696.5"
                     /locus_tag="K9S39_RS42035"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /product="phosphatidylserine decarboxylase"
                     /pseudo=""
                     /transl_table=11
                     /translation="SYQAHVNTRGLAFIECGPELGSRMVCAVVIGMDEVSSISWSVSVG
                     DTVQRGQELGWFSYGGSSMALVFEPGIVDEFTVPFNDPHEHPDDGPTVFVRSQIARAR"
     gene            complement(10001..10609)
                     /locus_tag="K9S39_RS09035"
                     /old_locus_tag="K9S39_09110"
     CDS             complement(10001..10609)
                     /GO_function="GO:0010333 - terpene synthase activity
                     [Evidence IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /GO_process="GO:0046246 - terpene biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: T1TS"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1052: Terpene synthase/cyclase metal-binding domain
                     protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF040195.4"
                     /locus_tag="K9S39_RS09035"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="K9S39_09110"
                     /product="terpene synthase family protein"
                     /protein_id="WP_248862801.1"
                     /sec_met_domain="T1TS (E-value: 3e-36, bitscore: 124.7,
                     seeds: 237, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MGHRTAGITPALNDYASMRQHTAAGSATLAWAEIVDGEEIPGRES
                     DAPAVRALTELAFTTAAWDDDLFSYGKELWFARRERTPSPCRLNLVDILRHEYGHSYEQ
                     ALREAGQLCDRLTLRFVELRDRVLTRASAPLSAYLDHLSHLIPGNLAWGLAADRYRNPD
                     GRSPDAVTTSGSTTSTPPKDTSPVPIPSVAWWWDPGLGA"
     gene            complement(11013..12086)
                     /locus_tag="K9S39_RS09040"
                     /old_locus_tag="K9S39_09115"
     CDS             complement(11013..12086)
                     /EC_number="1.14.19.-"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) delta12_cd03507"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF012699.5"
                     /locus_tag="K9S39_RS09040"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="K9S39_09115"
                     /product="acyl-CoA desaturase"
                     /protein_id="WP_248862802.1"
                     /sec_met_domain="delta12_cd03507 (E-value: 6.5e-06,
                     bitscore: 24.1, seeds: 49, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAAELDNVYSRTIGTLDENDVRYLRSIVRAQRALEAAGRCTIQFG
                     RSRPARVAGVLALAAAKILDNLEIGHNVLHGQYDWAKDPHLHSDSYEWDTILPARLWRY
                     QHNFVHHVYANIYGLDENLRAGPIRLSVQQPWQPHHIAGPLLLLATAPIAELAIALHAA
                     DEIGRGSTSSDLKSTPKRLRQDILLKAARQAAKDLVLFPLLSGRRAGDTLIANSSALVL
                     RNLWIFAISLCNHYPEDVTVFNQDVLENETRGQRYVRQIRGAANIEGSRMLHILAGHFT
                     HHIEHHLFPDVPSSRYREISYQVRNICERYGIPYTTASFPAQIASAFRNLCALALPPNG
                     RKSFARRSRRHESGDWR"
     gene            complement(12172..13230)
                     /locus_tag="K9S39_RS09045"
                     /old_locus_tag="K9S39_09120"
     CDS             complement(12172..13230)
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1094: ferredoxin"
                     /gene_kind="other"
                     /inference="COORDINATES: protein motif:HMM:NF012402.5"
                     /locus_tag="K9S39_RS09045"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="K9S39_09120"
                     /product="ferredoxin reductase"
                     /protein_id="WP_248862803.1"
                     /transl_table=11
                     /translation="MLRPVAGLLTSPHSVDTYLELIHPAWTRSEVRAIVTRVEHPTAAA
                     VTLTLRPNQAWRGHMPGQHVQLGVQIGGVRRARTFSIASSPDRPDGLLEITATCTGGRF
                     TTYLRDKVRVGTVVALSTAQGQFVLPQHTPEGLLFICGGSGITPALSMVRTLVMRNRTE
                     PVGLLHYSRSPDLQLYRRQTEALSKRHSALQLLTFFTRGQRATGSVHFSERHLNEIPGY
                     AAREVFVSGPAELISAVTTHFNARHPRTRVHAECFQPATPTDRQSEGRWLVEFATSGRR
                     AQSSGECLLDQAENMGLTPEYGCRQGICGRCIRPLIRGSVSDVAAGNTISEPGSPVRLC
                     VCVPESDVVLDL"
     misc_feature    complement(13030..13032)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            complement(13946..15193)
                     /locus_tag="K9S39_RS09050"
                     /old_locus_tag="K9S39_09125"
     CDS             complement(13946..15193)
                     /NRPS_PKS="Domain: Aminotran_1_2 (47-379). E-value:
                     2.9e-49. Score: 160.0. Matches aSDomain:
                     nrpspksdomains_K9S39_RS09050_Aminotran_1_2.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Aminotran_1_2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1109: 8-amino-7-oxononanoate synthase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF012382.5"
                     /locus_tag="K9S39_RS09050"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="K9S39_09125"
                     /product="pyridoxal phosphate-dependent aminotransferase
                     family protein"
                     /protein_id="WP_248862804.1"
                     /sec_met_domain="Aminotran_1_2 (E-value: 4e-47, bitscore:
                     160.0, seeds: 48, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDVLDKCRSWTTDHLRSIGLDSYYRTVDDCFGGTEAHFEGRRVVI
                     AASHDYLGLSGDDRVREAAVEAVRRYGTSLGCSRAVSGSLALHEDLEDRLARMLGQQAA
                     AVVPSGFQANLMLAPLLGTGDVAFSDFANHASLRETVGLSAGEERRFRHADLAQLEQML
                     DAAPSQAGKVVLTDGMFSVDGDVCDLPGITRLARACGARVVVDSSHDLGVLGVNGAGVT
                     EHFGTGADIVTSALSKSLASVGGVIAGPSEMIHYLRFHARAFTFTAAASPANVAAALAA
                     LEILQSEPERRIRLLTLAERLHNGLRAMGFDTGGSTTPVVPVHVGERMRCFRTWQALCE
                     AGVFSTPMVYPAVPEGSELLRITLTAAHTDGHLEQVLTAFEQVGRKEGIIPDSTPDTYT
                     PVRITGLPVQAQARPV"
     aSDomain        complement(14057..15052)
                     /aSDomain="Aminotran_1_2"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_K9S39_RS09050_Aminotran_1_2.1"
                     /evalue="2.90E-49"
                     /label="K9S39_RS09050_Aminotran_1_2.1"
                     /locus_tag="K9S39_RS09050"
                     /protein_end="379"
                     /protein_start="47"
                     /score="160.0"
                     /tool="antismash"
                     /translation="SHDYLGLSGDDRVREAAVEAVRRYGTSLGCSRAVSGSLALHEDLE
                     DRLARMLGQQAAAVVPSGFQANLMLAPLLGTGDVAFSDFANHASLRETVGLSAGEERRF
                     RHADLAQLEQMLDAAPSQAGKVVLTDGMFSVDGDVCDLPGITRLARACGARVVVDSSHD
                     LGVLGVNGAGVTEHFGTGADIVTSALSKSLASVGGVIAGPSEMIHYLRFHARAFTFTAA
                     ASPANVAAALAALEILQSEPERRIRLLTLAERLHNGLRAMGFDTGGSTTPVVPVHVGER
                     MRCFRTWQALCEAGVFSTPMVYPAVPEGSELLRITLTAAHTDGHLEQVLTA"
     gene            complement(15272..16105)
                     /locus_tag="K9S39_RS09055"
                     /old_locus_tag="K9S39_09130"
     CDS             complement(15272..16105)
                     /EC_number="1.-.-.-"
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1001: short-chain dehydrogenase/reductase SDR"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF012334.5"
                     /locus_tag="K9S39_RS09055"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="K9S39_09130"
                     /product="SDR family oxidoreductase"
                     /protein_id="WP_248862805.1"
                     /transl_table=11
                     /translation="MTTALVTGASYGIGHEIAHELAARGYDLILVARSADALYDLAHDV
                     ESRYTVSTTVLPANLAAPGELELVANSAGAIDILVNNAGAALAAPFTSTAWEGQKATEK
                     AMLALNVSAPTRLIHAALPQMMRRGFGRVLNIGSVSGTAPVWASSTYGPSKAYLLALTQ
                     SISRSREIRASNVRLTCLVLGHTVSEFHKRAGIPPSPRVITLPARFIANAAVRAIHRPS
                     PPVTYVPSIRYKFLNSLVKYAPQVLTMAPGLVTDFTAAGGEQHQSCARDADFRAS"
     misc_feature    16396..16410
                     /note="TFBS match to NrdR, Represses ribonucleotide
                     reductase encoding genes, confidence: weak, score: 21.38"
                     /tool="antismash"
     misc_feature    16974..16989
                     /note="TFBS match to ColR, Phenol-responsive regulator,
                     confidence: weak, score: 18.99"
                     /tool="antismash"
     misc_feature    complement(16977..16993)
                     /note="TFBS match to ZuR_variant_2, Zinc-responsive
                     repressor, confidence: weak, score: 22.54"
                     /tool="antismash"
     misc_feature    16978..16987
                     /note="TFBS match to ToxT, Regulator of MSHA biosynthesis,
                     confidence: weak, score: 15.0"
                     /tool="antismash"
     gene            17165..17719
                     /locus_tag="K9S39_RS42925"
     CDS             17165..17719
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF024935.5"
                     /locus_tag="K9S39_RS42925"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="transposase"
                     /protein_id="WP_406707895.1"
                     /transl_table=11
                     /translation="MAERLPDRNMQALQQLGRLFPLHHVQPVGSGACGTGARGRCRKTQ
                     NVIEPSALVIDDTGFLKDGEASACVSRQYTSNSGKFTKCQAGSPSSPGLRPRLGHCELA
                     SVPPQDLEPASPRADTDRRGRSSPRRVRARPAIAEEEDADRPDARRGRRWTHEPGSGRW
                     PTCAAAAATSSPTARSPVPAA"
     gene            complement(17828..18418)
                     /locus_tag="K9S39_RS09065"
                     /old_locus_tag="K9S39_09140"
     CDS             complement(17828..18418)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1298: putative carboxymuconolactone decarboxylase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF014664.5"
                     /locus_tag="K9S39_RS09065"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="K9S39_09140"
                     /product="carboxymuconolactone decarboxylase family
                     protein"
                     /protein_id="WP_248862806.1"
                     /transl_table=11
                     /translation="MARITLRDPATMTPRERELYDLFPINLVRAMLVADPDVTEAFLRQ
                     GNALQNSALSPPLRELTILRVAALTGCDYERHHHEPRAKQVGASDKDIVAATTGDLSAL
                     DPTQAALLRYAEECVTKRKASVESFEAARAALGDNGVAIATMLIGHYVLNAIFAESLEV
                     DTDQQPPDWSSADKKDQSPAGEAAPGRRVNPSS"
     misc_feature    complement(18396..18409)
                     /note="TFBS match to BldD, Development and antibiotic
                     global regulator, confidence: weak, score: 19.48"
                     /tool="antismash"
     misc_feature    complement(18499..18513)
                     /note="TFBS match to OsdR, Development and stress
                     management regulator, confidence: medium, score: 24.85"
                     /tool="antismash"
     gene            complement(19019..20209)
                     /locus_tag="K9S39_RS09070"
                     /old_locus_tag="K9S39_09145"
     CDS             complement(19019..20209)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF016777.5"
                     /locus_tag="K9S39_RS09070"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="K9S39_09145"
                     /product="amidohydrolase"
                     /protein_id="WP_248862807.1"
                     /transl_table=11
                     /translation="MTRQNISEENGARTLQRRTCQDTSEEKRAMTHSLAGVVDGIIDTH
                     VHQWDPFTTPRQASPAAKFYRAAPHLVEKAFGKLAPVKQRQLILTPRYVAQPFLPEQYA
                     ADAEGVAKVVGAPVVALVHVEAGWQGKEPLAPVEETKWLISLPWGSDGLPDLVAITAHA
                     NPTDPHCGTLIDAHLQASPKVTCIRQLAAWHPDPKVLNWFDEPGLLKSRDFLAGFSAIA
                     ERGLPFEATVYSGQLPDVEILAHEYPETTIIVSHYATPVGVFGPTGTDTGDTAAKRADI
                     YRTWKDNIAAVAERPNVVAKHSGCAFPQLGFGHSPDGNIGGLEKLQELLQPMVDHVTDS
                     FGPDRVMFGSNFPMDKPNASLPDIIGMLVNVLGPRGEDVLRKVFRDNAMRVYRIDA"
ORIGIN
        1 ctgcggtcac ggcgcgcgcc gcttcccggc cgcgatccgg atcgggctcg aagactgcta
       61 catcgttggc ggacggtcgt gcagaatccg ctggaacagc cgatgatcct gccactgccc
      121 attgatgtgc ggatagcggg gtgcgatgcc gatggcctcg aaaccgcagc gctccaggac
      181 gcgttggacc gtatgttgtc cagcagcgtg gtggcctcga tccggtgcag ccccagttcc
      241 tcaccggtca cacggcacac ccgctcgacc gccgcagtgg ccaggccccg ggccttggtg
      301 gtcggcggcc gtccagtagc ccagataggc actatatatc ggctcacaat gtatcctcac
      361 agacatggcg tcgaaaccac tgaccgaggc ggtcttcttc gtgctcctgg cgctgctcga
      421 cgagccgcgc cacgggtacg gcatcaagca ggaggccgcc gcactctccg accagcgggt
      481 cgatctacgc gtgggcactc tctacggcgt ccttgaccgg ctcacggccg agggcctggt
      541 cgagcacgac cgcaacgagg tccaccaggg ccggctgcgc cgctactacc gcctcaccgg
      601 cgacgggacc cgggccctgg aggcggagaa ggcgcggatg gccgccaacg tcagggtcgc
      661 cgagcagcgc ctgacgggct ccggttcgga cgtcgacgcc cccgcagcac ccaagtcccg
      721 cgggcgggcc cggcctgccg gagcaggagg tatcgcatga acacgtcgga cacgctgctg
      781 gaggcccggt tccgcgccgt cctacgcgtt ctgcccgcct actaccgaca ggaacgcgag
      841 gaggagatgg tcgacacctt cctcagcgac cacgagccgc tcgacgagga cacggccctg
      901 ggccgtcccg ggccccgcga ggtcgcgggc gtcctcgtcc tggcggtccg cacccgcctg
      961 gccgggccgg gcgcccccgc ccgttacgtc gcctacggcc ataccgcgcg actggtcggg
     1021 ctcttcgggg tggccctgct cgccgcctcg acggcggtga gcttgctggc cgaggtggcc
     1081 gtcctcctgg cgggttcggc tcaggagagg cagttggtgc tcggcgcgtt cgtcgggcgg
     1141 tcgcagggat cgacgccgga cgccttcacc acgggctggg ccttgatggt cgagcttctc
     1201 cccctgggct ggatcgccgc cgctgtggcc ctggggacgg gccaccggcg acgggccgcg
     1261 gtcttctgtg ctgcggccgc cgtgcccacg tttgtggatc tggggcagtc ggcgagactc
     1321 ggcttcctgc cgagcgcttc gtccctggcc gccatcgccc tcgtcgtcgc tgtcaccgcg
     1381 tccgtgacga tggccttcca tcccgcggct ccccgcgtcg aggtctcgcg cctcacgagc
     1441 gagtggatcc cggtcggctg cttcctgatc ctgctcgccg ctgtcgtggc aggtcggctc
     1501 gtcctgggct tcgacgacgg gagctacggg tgggcgttcc tggtcggcgg cgtggtctgc
     1561 ctggtccttc gggtgcggaa ccgcgaccgg cacccggatg ctccgcccct tcacggagcg
     1621 gatccgcgcg ccttggcctc gggtcccgcg ctgcccgcgg ccttggccac tctcggtctg
     1681 cccgtcctga ccatgcgtct cgacgcggcg gccttgttca cgagcactcc tggggttccc
     1741 gccgaggcac tcgtcaccaa cgtggcccag tctgtggctg tcgcgatcct cgaagccacg
     1801 ctactcgtgg tcgcggtccg cgcgctccgg cgtgaatccc gtacgtggcc ttcctcgacc
     1861 gccgtctccg actactcctg cgcccccggc tcccacccgt aactcccctc ccgcatatgc
     1921 ggggcaacct gcgcgagatc tcggaagagg gggccttgga gcggctgcgt cagccgtacg
     1981 ggacagagac gggtacgggt acgggagcct gcctctcgcg ccgcataccg caaggacatg
     2041 tggcgtgcgc acaccgaggg ccccggcgaa gtggtcagcc gctgctgctg accgcatctc
     2101 cgtggccgcg gcgcgacgcc cccggtcagc gcgtggctat ccgcgcggcc acgcaggggt
     2161 cctcgttgcg gtagccgagg cgggtgtaga gccgttcggc gggggagttg tcggcgagct
     2221 gccacagcgt gcagaacccg tgctgccgta tggcatgccg ggtcagccac gaggtcagcg
     2281 ccgcgccgag cccctggccg cgcaggccgg cgtccgtcgc gaccgacgcc atcagcggag
     2341 cgccgctgtc ccgcaggctg ctcaaggcac cacaggccac cagccgcccg tccgcgtcgc
     2401 gtattccgac ccacagggtg acgtcggagg aaccgggccc ggtcgagtgg tccgggctgt
     2461 gttcgttgag gaaagcgagc agctcctcat ggtgcgcctc gtcgagctcg accactcgct
     2521 cctcggcccg gtggacaggc ggttcctcca gcgtccagcg gaagacccac tcgacgacat
     2581 cggtcaccgc cagatggcgg ccgaccagga cgtcggtgcg acggggcccg gtgaactccc
     2641 gcacctggcc gggaagtacg tgcgcggcac gcaggacgag tccggcggcg gcctccggtt
     2701 cgccgacact ccacacgtga ccgcgggcgt cgtcgaacca agcggcggca ccgtcgccgg
     2761 accagccgat ccggtcgtcc tggcgctgcc gcgcggcgcc gaaacgcagc agggcggcac
     2821 cggcctggga ttccaggccc tggtcgaaca ggtcttccat ccggtggaca agggtcgttg
     2881 cctgcattgc tctctgagga aggacgtacg ggggccgaca gggcccggac acgcgtggac
     2941 gcagccggaa ccgtctgtct caggtatggg gagcccggta gcggctgcgc acgaggcgcg
     3001 cccggccgac cggacggccc actgtcgcac accgcccctg gcgtggggca aattctcgac
     3061 tcatccgccg acgacgcctg ggcctgccgg tggatgccct ccgtacacgt gccccctggg
     3121 ccgacccggc tgcgcggcta cttgcctacg cggtacggcg cgattccgct caagccccgt
     3181 gtgcgcattg ccatggaggc ggaccagggc ccagtccccc ggccgccatg aggtggcagc
     3241 agtggcgcga cagggcgacc aagccgacgc aaggcgatca gcggcgccgc gtcagacacc
     3301 tggcccggct cgaagccctg cccgaaacgg cccaccaggg gtcttccgga gaatccgact
     3361 ggccgtcatg gaaattctgg attcatttcg ccaggaaacg aagaaccaga aacggagaac
     3421 aagccaagct gcggtacttg ccgctggctt cattactctg tactacccgc cagtcggcct
     3481 gccccagcat ggcggatcag tgtgtgcgca gcgttttcct ttccctctct gcacagcgct
     3541 ttcacgccga aaagcgtgtt tacgccacaa gggcggtggc cggttctcgg taccagcccg
     3601 atgacgcggg gttgagcggc cccagcgaat ccgggaacct gaacgctcgc catccgcgga
     3661 aggatttcca tgacccgtga caccccacac ctctggaccg aacagaaact cgacgcgcgt
     3721 tacgagaatt tgttcgggcg ggcggccgga tatctgccgg agaaccgggc agcactcgac
     3781 gcgtggctgg atgacttcag tcgggacgtc catgagcggc gcgcccggaa cgccatcgtc
     3841 aggcacccgt ccgtggcgga cctggcgcga ctcatcgagc gcgacagaat cgtacgcatg
     3901 tatgtgagcc gcatgatcaa cgaggcccac caacgggact gcaagaacac ggtgaacgac
     3961 attcccgatc tgctcgatca cctggactgc atcgtcacca gcacgcccaa gtaccagggc
     4021 cccaccgcct tccccatgtc ggccctgttc acctacctga tgatgacgac cgatggttac
     4081 gcggtattcc gtgaccaggg attcaacaaa gcgctgctcg gcatcctgcg ggagtggtgc
     4141 gcccacctgg acagcaagga cagtcaggag gtcctgaacc aaaagaacgg ctggctgtcc
     4201 ccggccgcct tggcggacaa gaaactcaat ctccaggatt tccagatcaa tctgcaggac
     4261 ccctacggcg gatttccctc cttcaacgcg ttcttccacc gcgagctcag gaaagacaag
     4321 gacgtccggc cgatcgacga tccggacgac ccgcggatca tcgtttcggc gaacgacgga
     4381 aaggtggtgc ggatccggcg ggacatcaag cggagcgacg aattctgggc caagggacag
     4441 cgctactccc tctacgacat gctcgacgga agcgacctca ccgacctgtt cgtcggtggc
     4501 gacgtcttcc agtccttcct gtcgggcggt gattaccacc gctggcacgc gccggtgagc
     4561 ggcgtcgtac gcagcgcgcg ggtggtcgag gccctgatgt tcaccgaact ggagcacacg
     4621 agcgggcgcg atgccggcac ggagtcgcag gtctacggag cgtcggtgaa cacccggggt
     4681 ctggtgttca tcgaatgccc gccgccgatc ggcatggtgt gcgtcatgcc tctgggcatg
     4741 accgagatct catcggtcac gctcacggtg caacccggcg accaggtcac caagggccag
     4801 gagatgggct acttcagcta cggcggctcc agcatgtgcc tgctcttcca gaagggagcc
     4861 atcgagaaat tcttcccgaa ggacaacacc ggggacatgg aggaaggcga cccgatcaag
     4921 gtcaacgcaa ggatcgcgca ggccgtcggc gacgaggcct gaggggagac ggggatggca
     4981 gggaaggcat gagaggggag aggcacacca tggccgcgaa agagtcgcca ggaaacgcct
     5041 gtggccggcc gaccgcagga gaggaactcc acgtctgcat gggtctcaac gcctgcgcgg
     5101 gccaggacgt cggcgggaag gcgaccatgg ccggcaccgg ccagtgcgcc acggtgcagc
     5161 acgtctgcca cggtgaggga gcctgccgtg gccagggcgg ctgcggttac gccggggacg
     5221 acttcgagca gttccacccg ggtgaacagt cctgccggta caacggcagc tgtgccagcc
     5281 ccatcaacga gagccgggtc ttctccgccg gcccgttgaa gggcaggagc gtctggcagc
     5341 aggcgcgccg cctcttcgaa gcgcggatgt acgcggcggg caaggcattc ggcccgtccc
     5401 ccgggcaggg cgtccccgat gaccgcttcc ccgactacga ccgtctggag cccgggcaca
     5461 ccccggtgcc gggatcgtcc gacgaggcca ccgctctctt ccgggcctcg gcggacaatc
     5521 ctcgccggca cgagggcaag gctttcccgg acctgcaggc catcgcccgc aatggcatcg
     5581 gtcggcacct gccgaacgtg agcatcacct tcaccatccc gccgagcgcc tcctccctcc
     5641 tgtacttcca gcgggacggt gaggcgaaga ccagcagctg cacggtcgcc accggcgcca
     5701 cgggggtggc caccgccctc cccctctacg ccggacacac cagccccaac gaccaatggg
     5761 tgaccgtgac cgccaccggc cccgtctacg ccaacggctc cgccacatgc gaattccatg
     5821 tcacggtcct ggcgcccgag gagcagcaat agcgccggga gaggcggccg gcacggcgac
     5881 gcggacaggc agcgcagccc aacgcaccac ccctgatctg gggttcggac tcggactgcg
     5941 cggacctcac atcccgtata tccgcgagca ccggccgccc gtcgacttct tcgagatcat
     6001 ctccgagaac tatctgaagc cccggaccgc ccggcgacgt gccctggacg agatcgccga
     6061 gcgctatccg atcgtcctgc acggggtgtc cctgtcgatc gggagcaccg acccgctcga
     6121 cctcgactac ctgcgtcacc tgaagcgcct ggcggacgcc gtggacaccc cgtgggtgtc
     6181 ggaccatgtg tgctggaccg gagtgctcgg cgtgcacact cacgacctgc tgccgctccc
     6241 cttcaccgag gagtcgctac ggcatgtcat ccagcgcgcc cgcaccgtgc aggacatgct
     6301 ggagcggccc ctcctcctgg aaaaccccag cagctacctg cagttccgcg cttcgacgct
     6361 caccgagtgg gagttcctgg gccggctggc cgaggacgcg gactgcggac tgctgctcga
     6421 cgtcaacaac gtctacgtct ccgccgtcaa ccacggcttc gacccggaga cgtacctgaa
     6481 ggctctgccg caccaccgcg tggcgcagat gcacctggcc ggacacaccg actacggcac
     6541 gcacctgatc gacacccacg acgcggacgt gccgaacccg gtctgggagc tgtaccggct
     6601 cgccgtggag ctcaccgggg gcgccgccgc caccctcatc gaacgcgacg acggtctccc
     6661 gcccttcccc gtgctccggg ccgaactcga cacggccagg gcagtggccg cggcagccat
     6721 cgggcaggaa ggcggcggcg atgactgacg tcccgtgctc gctcgcggcg atacagcggt
     6781 ggatgcaggg cgcgctgctg gcaccgggcg gggccgcgca ggcgacggag ggggcacaga
     6841 cggcgcaggt ggcggaggtg gtcgccgcgc ccgggcggct gacggccgag gagtgcttcg
     6901 gtatctacta ccgcggctac cgcctccggc tgctgcgctg catgcgcgac cagtaccccg
     6961 ggatggtccg tctactgggc cgcgagctct tcgaccggtt cgcgctggac tacgtggacg
     7021 cgcacccgtc ccgctcgccg agcctcgacg gcctcggcgc cggcttcccc ggccatctgg
     7081 cccgtacccg accggacgcc gcctcggacg gcgcgccacg cgaggagtgg atcgacctgc
     7141 tgatcgatct ggcccggtac gagcgggatt tcgcggccgt cctcgatggc cccgaggccg
     7201 acgggggcgc cgccccgtgg accgagccgg agcccggctc cggggccgac ccgggctccg
     7261 gctcgggggc gggcccgaac tccggctcgg ggacacggct cttcgaggcc cagttccccg
     7321 tccaccgcta cgccgccgcc gtccgccgcg gggaagaccc ggaaccgccc accgccgaac
     7381 cggtcttcct cgccctgtcc tgccagaacg gcaccgtcgt cgtccacgac cgcgccgaat
     7441 cccgctaccg gacccgtcag acggcgcacc ggccgtcccc tgccgcatga cgtccgcact
     7501 ggaggaaccc catgccccac ctcacgactc ccctggccgt ccgggcgatc gacggcatca
     7561 ccacccgcga cgaactggcc gatcacctcg gcgacgcggc acgcatcgag ctgtcgacca
     7621 ttccgcccta cccctacgcg gcgtactccc tcaagacgcc cggctactcg cagcgggccc
     7681 agggcgcatc agcgcagcgc accctcatcg gcatcgcgat cgaggagatg ctgcacatgg
     7741 cactggtgcg gaacgtgatg gtcgccaccg gctgcgagac ggtgaagacg aaggacggga
     7801 atcagcggaa ggcgtcccgc ttctacgaca aggacagcat ccccacctac cccggtgaca
     7861 tgagccaccg caccccaccc ctgccccttc acctgcagcg catctccacc gccgccgttg
     7921 aggggttcat ggaggtcgag ctccccgaga ccgcacagca gcagctcctc acatccgccg
     7981 acgactactc gtaccagaca ctcggcgagc tgtacgacgc gatcggcaag ggcatcgtcc
     8041 acctgaccgg aacgaaagac atcacctggg gactgacgga gtcccgctgg cagcagcagt
     8101 acctgcgggc gttctggaac cagtggggag gcccgcccaa gcccatcccg gtcgtggacc
     8161 aggggagcgc actcgacgcc ctctacatca tcgtctccca gggcgagggc gcccccgacg
     8221 agcaggagga gtcccactac gagaagttca cccgcatccg cgaccacgtg gacggcatcg
     8281 gtgtcgtgtg cgacgactcc ggacggcaaa aatacaccat cgacagcgga gacgaggccg
     8341 tctggccggt ggtgaccgac ccgaacgcct ccgacttcac cggatcgctc aagcagctgg
     8401 cactgctctc cgacgcggct tactgctatg tgctggcgct gctggacaag ctctacctga
     8461 ctccggcgga cgaccccgac tccggccccg ggcagggcga gccgcacccg acgtccaagc
     8521 ggtacgccct cgaacgcggc ttcatcgccg ccatgcaggg agtcctctct ccggtcgcca
     8581 acatcctggt gagcacaccc ctcaccgacg ggccgaacgc cggccggcac gccgggccca
     8641 cgttcggcca ctacgacttc cagggcgtgc cgcccaggca ggctctcctg gacctgtgca
     8701 ccgacaagga cctggcgacg gacttccccc aactgggcgg cagcgacggc gtcctgaacc
     8761 agatcaggct gctccccgac ttcacgatct aggggtcggt gggcctgtcc cagaacccac
     8821 gcgacacgtg gacgccccgt agacgaccgc aggcgccccc gtaagcgaca ccctcgattt
     8881 cgtcgtcacc tgggcgccgg cgttcgaccg ggacccacgc aagcagatct tcctgccgat
     8941 gtccgcgctg ttcggctatc tgcgtctgac gccggcgggc gcggtcgcct tccgcctgcc
     9001 gcagttcaac gacggtctcc gggccattct ccagaggtgg tgcacgtacc tgaacagccc
     9061 ggagagcgcg cacgtgctca acacccgtga ctggttctcc cagtccgcca tcgagctgaa
     9121 caagctgtac gagtaccagt gctgggactg ccgcgaccag gagcactggg gcttctcgtc
     9181 gttcaacgca ttcttccacc gcccgatcaa ggacgagtac cggccgctgg cgggccacgg
     9241 agaccccgcg ccgtcgtcgc gccgaacgac ggcaccgtcc accagatccg gcgcaatgtg
     9301 gccaggcagg cggacttctg gctcaaggag cagtactcgc tggaaaccat gctcagcgga
     9361 ccggagtgcg gagccgagta cgtcagcagg ttcgtccgcg gcgatgtgta ccagtcattc
     9421 ctgtcggtca acagcttcca ccggtggaac gtccccgtgg acggaacgat caagcacctg
     9481 gagatcgtgc cgggcctgat gttcagcgcc gccgaccacg agaggcccgg accccgagac
     9541 ctggacgcac tcgcagagct accaggcaca tgtgaacacc cgcggcctgg cgttcatcga
     9601 gtgcggtccg gaactgggca gccgcatggt gtgcgcggtg gtgatcggca tggacgaggt
     9661 ctcctccatc tcctggtcgg tctccgtggg cgacaccgtc cagcgcggcc aggagctggg
     9721 ctggttcagc tacggcggtt ccagcatggc cctggtcttc gagccgggca tcgtcgatga
     9781 gttcaccgtt ccgttcaacg acccgcacga gcacccggac gacggcccga ccgtcttcgt
     9841 acgctcgcag atcgcgcggg cccgataacc gctcgccgca ccgcaccacg gccgccggcc
     9901 tcaccgttca cgcggcgggg ggccacaggg ccggagaggc tcagggccgc aggcttgacg
     9961 ggctcgacgc ggcccttgcg gtcctgagga gttgtgcagc tcacgcaccg aggccggggt
    10021 cccaccacca ggcgacggaa gggatgggca cagggctggt gtccttcggc ggggtggagg
    10081 tcgtggagcc ggaggtggtg acggcgtcag gggatcgtcc gtcggggttg cggtagcggt
    10141 ctgctgccag cccccaggcg aggttcccgg gtatcagatg ggacaggtgg tccaggtagg
    10201 cgctcagcgg agcactggcg cgggtcagca cgcgatcgcg tagttcgacg aatcggaggg
    10261 tgagccgatc gcacagctgc cccgcctccc gcagggcctg ttcgtaggag tgaccgtatt
    10321 cgtgccgcag gatgtcgacc aggttgagcc ggcagggaga cggtgtgcgc tcacggcggg
    10381 cgaaccacag ctccttgcca taggagaaca ggtcgtcgtc ccaggcggcg gtggtgaagg
    10441 cgagttcagt cagggcacgc accgcaggcg catcagattc ccggccgggg atctcctcac
    10501 cgtcgacaat ctccgcccag gcgagcgttg cggaacccgc tgcggtgtgc tgccgcatgg
    10561 aggcgtagtc gttcagtgcg ggtgtgatgc ccgcagtgcg gtggcccatc tcccaacact
    10621 tgcgcgctta tgcacgaggc gaacggcgca actgcactgg accccggtcg tgttgctgcg
    10681 ggggcttgct ggaacaccca tggacagggg gtgcggaggt tcaccggcac cagcgacgtc
    10741 tcctttcgga ccgaagccgg tgtcgaccgt cggaccgggg tcgcctacgc caaggccgat
    10801 gtgccctacg accggatccg ctccgactcg ccggtgcgcg ctctgttcag gagtccgtct
    10861 cctcgacaag ccgccggcgc aggccacccg ccgcccggca ccggccgagc gcacctcgcg
    10921 gccgaagccg aagccgccct tgcacgagca gagagtaatg ctcgctcctt gaatcgcgct
    10981 accactccgc cgcaagcgcc tagttgacaa ggtcatctcc aatcaccact ctcatgccgg
    11041 cgtgagcgcc gcgcaaagct cttgcgtccg ttcgggggaa gggcgagggc gcagaggttg
    11101 cggaaagccg aggcaatctg agctgggaaa ctcgcggtgg tatacgggat gccgtaccgc
    11161 tcacagatgt tccggacctg atatgagatc tcgcggtagc gagacgaagg gacatccggg
    11221 aagagatgat gctcgatgtg atgagtgaaa tggccggcaa ggatgtgcag cattcgactg
    11281 ccttcgatgt tggcggcgcc acggatctgt ctgacgtacc gctggcctcg tgtctcgttc
    11341 tccagaacgt cctggttgaa aactgtgacg tcctccggat agtggttgca tagtgaaatc
    11401 gcgaagatcc agagatttcg gagaacgagg gccgaagagt tggcgataag cgtgtccccg
    11461 gcccggcgtc ctgaaagaag cgggaacagg acgaggtcct tggccgcttg ccgggcggct
    11521 ttaaggagga tgtcctgacg tagccgcttc ggggtcgact taaggtcgga cgaagtgctg
    11581 ccgcgcccaa tctcgtccgc ggcgtgtagt gcgatggcca gttcagcgat aggggcagta
    11641 gcgagaagca gcagaggacc agcaatgtgg tgaggctgcc atggctgctg cacagagagg
    11701 cgaatcggcc cggctctcag gttctcgtcc aggccgtaaa tgttggcata gacgtggtgc
    11761 acgaagttgt gctgatagcg ccacaggcgc gccggtagga tcgtgtccca ttcataggag
    11821 tcggagtgga ggtggggatc cttcgcccag tcgtactgtc cgtggaggac attgtggccg
    11881 atctccaggt tatccagaat ctttgcggct gccagcgcca gtacacccgc cactcttgcc
    11941 ggacgggagc gcccgaactg gatagtgcag cggccagctg cttccagggc tcgctgagcg
    12001 cgtacgatgg atcgcaggta gcggacgtcg ttctcatcca gtgtgccgat agtccggctg
    12061 tagacgttgt cgagttcggc ggccaaatct gccagctgtt cttcgggaac gtgtgacgga
    12121 gtgactttcg gatatgttct actcatgatg gctttcagtc cgtaccgtta gtcaaaggtc
    12181 gagaacgacg tcgctttcag ggacacagac gcacagccgg acaggggacc cgggctcgct
    12241 gatcgtgttt cctgccgcca catcgctgac gctgcccctg atcagggggc ggatgcaacg
    12301 accgcagatg ccttgccgac aaccgtattc gggggtcagc cccatgttct ctgcttggtc
    12361 cagcaaacac tccccgctgg attgcgcccg acgcccgctg gtggcgaatt cgacaagcca
    12421 ccgtccctcg gactgtcgat cggtgggtgt tgccggctgg aagcattcgg cgtgtactcg
    12481 ggtcctgggg tgccgggcgt tgaagtgggt cgtgactgcg ctgatcagct cagctggccc
    12541 gctgacgaaa acctctctgg ctgcgtatcc cgggatttcg ttcaagtgcc gttcactgaa
    12601 gtgcacggag cccgtcgcgc gttggccgcg ggtaaagaag gtcaggagtt gcagcgcgga
    12661 gtggcgcttg gacagagcct cggtctgacg tcggtatagc tgcaggtcgg gactgcgact
    12721 gtaatgcagt agaccgactg gctccgtgcg gttgcgcatg acgagggtgc ggaccatcga
    12781 gagggccggg gtgatgccgc tcccgccgca gatgaacagc agtccctctg gggtgtgctg
    12841 gggcaggacg aactgcccct gggcagtgga cagggccacc accgtgccaa cgcgtacctt
    12901 gtcgcggagg taggtggtga atcgaccgcc ggtgcaggtg gcagtgatct ccagcagccc
    12961 atcgggccgg tcagggctgg atgcgatgga gaaagtgcgg gcgcggcgga cgcctccgat
    13021 ctgtacccct aattggacgt gctggcccgg catatggccc cgccatgcct ggtttgggcg
    13081 caaagtgaga gttactgcgg ctgcggtcgg atgctcgaca cgggtgacga tcgcccggac
    13141 ctctgaccgg gtccaggccg ggtggatcaa ttcgaggtaa gtgtccacac tgtgcggcga
    13201 tgtgagcaga ccagcgaccg gccggagcat atttccgatg atccgggcaa ccgttgctcc
    13261 tcggctgcgc cgcggcgcag tgggagtcgt catggcaggt cccaacgcac ggctgtcatc
    13321 ccgtgtccgt agagggcagt tgggtggacg tgcttcccat tcgtgcccga acaccgccgt
    13381 ccctgcgcgg gcgggcctcc gtatgggcaa cgccggcagt ggtggcgagc tgggcgcgga
    13441 acaggacgag gttcaggtct atgaggcacg cttcgagcac gaggctgtcg gcaccggagc
    13501 ggccatggag gggtggcgca tggccggacg ctctctccag caacttcccg tgccgcgtgg
    13561 gaccgatcgc gggattcgcc ggccttggaa caagggcggt ttggggagtc aagggtgggc
    13621 atccattcgg cgagcacctg tggaaccgcc ccaggatcgc ctgccagagc agtcggatgg
    13681 tgccattaac ccatctgtgg gcaagtctga tgaaagggtt tcggtgcccg aaagtagggt
    13741 tccggcccct gacgcgcagg ccgtggccga ggtgacagag gtcagcaacg tggccttgat
    13801 ggcccgcgcc gacctggcgg tccgtagctc ccatgaccag gggaggcatg accaggggag
    13861 gtgcgacgtc tcactcgtac gggaaagagc gtgatcgttc ctcctctgcg tacgagacag
    13921 gggcgccatc gaacccccaa ccgagtcaca cgggcctcgc ctgcgcctgc accggcaagc
    13981 cggtgatgcg caccggggtg tacgtatccg gcgtagagtc cgggatgatg ccttctttac
    14041 gccctacctg ctcgaaggcc gtcagaacct gctccagatg gccgtccgta tgcgccgcgg
    14101 tcagcgtgat gcgcaatagc tcactcccct caggcacagc gggatagacc ataggagtgc
    14161 tgaacacccc cgcttcacac aaggcctgcc acgttcggaa gcagcgcatt ctctccccga
    14221 catgaaccgg cactaccggc gtggtcgaac cgcctgtatc aaaccccatc gcccggagtc
    14281 cgttatgcag ccgctcagcc agcgtcagca accggatgcg gcgctccggc tcgctctgca
    14341 ggatctccag ggcggcaaga gccgccgcga cgttggctgg agaggcggcc gctgtgaaag
    14401 tgaaggccct ggcgtggaaa cgcagatagt ggatcatctc cgaggggccg gcgatcaccc
    14461 cgccgaccga ggccaggctc ttagaaagcg cacttgtgac gatgtccgca ccggtgccga
    14521 aatgttctgt gaccccggcg ccgttcacgc cgagcacgcc caggtcatgc gaactgtcca
    14581 ccacgacccg ggcgccgcag gcccgcgcga gccgagtgat gccaggaagg tcgcatacat
    14641 ccccgtccac tgagaacatc ccgtcggtca ggaccacctt gccggcctgg gacggcgccg
    14701 catcgagcat ctgctccaac tgcgccaggt cggcgtgccg gaacctcctc tcctcacccg
    14761 cgctcagacc gacggtctcg cgcagtgagg catggttggc gaagtcactg aaagctacgt
    14821 cgccagtgcc caacagcggg gccagcatca ggttcgcctg gaagcccgag ggcaccactg
    14881 ccgcggcctg ttgcccgagc atgcgcgcca gccggtcctc caggtcctcg tgcagcgcca
    14941 gtgagccgct gaccgcccgg gaacatccaa gcgaagtgcc atagcggcga acggcctcga
    15001 cagccgcctc acggacccgg tcatccccag aaaggcccag gtaatcgtgt gaggcagcta
    15061 tcactacccg cctgccttcg aaatgtgcct cagttccgcc gaagcaatca tcaacggttc
    15121 ggtagtagga gtcgagccca atgctccgca gatggtccgt agtccaggag cggcacttat
    15181 ccagcacatc catcgcatgt tctcccgttc gccgacgagg gtaactatcg aaactccagg
    15241 aggtcctgtt cgtactgcgt tcgtactgcc ctcaacttgc gcgaaaatcg gcgtcgcgcg
    15301 cacacgactg gtgctgttca ccccctgcgg cggtgaaatc ggttactagg ccgggggcca
    15361 ttgtgagtac ctggggagca tacttgacca gggaattaag gaacttatag cggatgctgg
    15421 ggacataggt gaccggcggg ctggggcggt ggattgctcg gacagctgcg ttggctataa
    15481 agcgagcagg gagagtgata accctcgggg agggcggaat tccggcacgt ttgtgaaact
    15541 cggagaccgt gtggcccagc accaagcatg tcagccgtac gttcgatgca cggatctccc
    15601 gagagcggct gatcgactgg gtcaacgcca acaaataagc cttgctcggg ccataggttg
    15661 atgacgccca gaccggagca gtcccgctta ctgagccgat gttgaggacc cgcccgaagc
    15721 cacgccgcat catctgcgga agcgccgcat ggatcaggcg agtcggtgca ctgacattga
    15781 gcgcgagcat tgccttctcg gtggctttct gcccttccca agcagtactc gtaaaagggg
    15841 cagcgagagc tgcgccggcg ttgttgacaa ggatgtcgat ggcgcctgcc gagttggcga
    15901 ccagctccag ttcacccggg gcggcgaggt tcgccggcag aactgtcgta ctgactgtgt
    15961 accgggattc gacgtcgtgg gccaggtcgt acagggcgtc agcgctcctg gcgaccagga
    16021 tgaggtcgta tccacgtgca gccagctcgt gggcaatttc gtgaccgatg ccgtagctgg
    16081 cgccggtcac cagcgctgtg gtcataggtg ccttctaaag cgcaaaccga gttggagtgg
    16141 gccgcacagg tgcggcctga tcattgttcc tatctcgcaa gatcttgctc gttcctcgcc
    16201 aagacaagcg tcgctaccgg acagcaaggc cgagttcgtc agacgccgcc tacgtagcgc
    16261 acgacttcac gaaaccagag gttcccaccc agtgccactt gccgccgcta ccccaccatg
    16321 cgaagcacca gtgccgtgcc cgatgccctg accggatgtg caaccgctct tgcccagcat
    16381 ttcccgggct cggccacacc agttctgggc tgtcaaaatc ctgtgggaac cccgcattcc
    16441 acctactagc ggcgcacccg agtgggtgac gcgttcggaa agtcgatgcg acaggggcta
    16501 cagaccgaag gcgacccaga cctggctgcg tagacgaggc atacacaccg tgttcccgaa
    16561 ccggccgacc aggagcgcaa ccagcaccgg cacggctgcc ggatgcgacc ccgaaccttc
    16621 ggatacagct ctacacccac cgcaccgtgg tggcagactg ttccaaccgc ctgaaacagt
    16681 ggcgcggcat cgccatccgc cccgaccgtt tccacgcgat accactcgac ctcgacctcg
    16741 acctccctaa gtcttgcgac gctgcgggtg atcagtccag tgccttgaca gccgcgaagc
    16801 ttcttgagca gctccctcgc gcggtagcta ctcccatgcc tggctgacga tttgcttgtt
    16861 atgtcgccgc cacagttccc ctccgccata gttcctctcc gtcatagttc ctctccgtca
    16921 tagttcctct cgaccactat cgcgacggcc gtaagctcga aggctggtag cgcttcatgt
    16981 ttttttgtac cgatcttggc tggtcggggg cgcggtggca tggggaggtg gaacggctcc
    17041 ggggtgcgtt gttcggagtt cgttgctgat atgttcgcct cgctatccgg cggaatcagc
    17101 gtcggtgggg tgggtgttat ctgcgcgtct gatgccggac ggtcgacgta agccgataca
    17161 ggcgatggcc gagcgactgc cggacaggaa catgcaggct ctgcagcagc tcggcaggct
    17221 ctttccgctt catcacgtcc agcccgtggg atccggcgca tgtgggaccg gggcgcgtgg
    17281 aagatgcagg aagacgcaga acgtcatcga gccgagcgca ttggtcatcg atgacacagg
    17341 cttcctcaag gacggcgagg cgtcagcgtg cgtgtcgcgg cagtacacca gcaactccgg
    17401 caagttcacc aagtgccagg cagggagtcc ctcttcacct ggcctccgac cacgcctcgg
    17461 ccactgtgaa ctggcgtccg ttcctcccca agacctcgaa cccgcctcgc cgagggctga
    17521 caccgatcgg cgcggccggt catctccgag gagggtgaga gcccggccgg ccatcgccga
    17581 ggaggaggac gctgatcggc cagacgcccg ccggggacgc cggtggacgc atgagccggg
    17641 cagcgggcgg tggcccacct gtgccgcggc ggccgccacg tcgagtccga cggcacgctc
    17701 gcccgtcccg gccgcctagg tgcggacctg gtgggcaatg cctggccgcc tcgatgaggc
    17761 gtggagacgg tcgcccctcc cctcgtcgtg cgcggcggtc cggctgcggt ctgcgtgggt
    17821 gggcatgcta cgatgatggg ttgacgcgcc tgccgggggc ggcttcgccg gcgggcgact
    17881 ggtccttctt gtcggcgctg gaccaatcgg gcggctgctg gtcggtgtcg acttccaggc
    17941 tctccgcgaa gatcgcgttc aggacgtagt gaccgatgag catggtggcg atcgctacac
    18001 cgttgtcgcc cagcgcggcg cgggcggcct cgaaggattc gacgctggcc ttccgcttgg
    18061 tcacgcattc ctctgcgtag cgcaacagcg cggcctgtgt agggtcgagg gcggagaggt
    18121 cgccggtcgt ggccgcgacg atgtccttgt cggaggcccc cacctgtttc gcccgcggct
    18181 catggtggtg gcgctcatag tcgcagccgg tgagggcggc aacccgcagg atcgtgagtt
    18241 cccgcagcgg agggctcagt gccgaattct gcagtgcatt gccctgacgc aggaaagcct
    18301 ccgtgacatc ggggtccgcg acgagcatgg cccgtaccag gttgatgggg aacaggtcgt
    18361 aaagctcccg ctcacgcggg gtcatcgtgg cggggtcgcg aagcgtgatc cgggccatcg
    18421 tggacctcct ctgtcgagtc tgcacggtcc tcactcagag cgaacgccga agcgagtcgg
    18481 ctcgacgggg ggggtggcag gtccggtggg cccaccgccg gcgatgagca cccgcgccgc
    18541 ctgcgtacgt gcccgggagc cccaaggctg gatgcctggg gtcacagctg ttccttcggc
    18601 cggctccgac tctactcaca ttacgacata tcgactcata agagggaaaa gcatgcttta
    18661 aacctggaac ggaccgcgtc ggcttcggcc cacgtcaagc cgacgcgccc gggcgtccag
    18721 gagaacggct gtccatttgt acgggggacc cggcaaccga gcacagccgg ccctcggcag
    18781 tggcccgcca gccgcaccca gtgctccccc gcacggccgg caaacacacc gcgacccggc
    18841 caccaaccgc agccgctccc ggcgtccgct cgtgggccaa cggcccggcg gtggcggcga
    18901 acagcacccg cagcggctcc gaccccagcc gctccctcgc ccaccggcac cacccccgaa
    18961 caccgcgccg gcagcgcacc ccccgagccg gcgaaggctg aggacaacgg catcggccct
    19021 aagcgtcgat ccggtacacg cgcatggcgt tgtcgcggaa caccttgcgc aggacgtctt
    19081 cgccgcgtgg tcccagaacg ttgaccagca tgccgatgat gtcgggcagt gaggcgttgg
    19141 gcttgtccat gggaaagttc gatccgaaca tcacacggtc gggaccgaag gaatcggtca
    19201 catgatcgac catgggctgc aggagttcct ggagcttttc gaggccgccg atgttgccgt
    19261 cgggtgagtg gccaaaaccc agttgcggga acgcgcaacc ggagtgtttg gcgaccacgt
    19321 tggggcgctc tgccacggcg gcgatgttgt ccttccaggt gcggtagatg tccgcgcgtt
    19381 tggcagcggt gtccccggtg tcggtgcccg tgggaccgaa cacgccgact ggcgttgcgt
    19441 agtgactcac gatgatggtc gtctcggggt attcatgcgc caggatctcg acgtctggga
    19501 gctggccgga gtagaccgtg gcctcaaagg gcaggccccg ttcggcgatc gcggagaaac
    19561 cggcgaggaa gtctcggctc ttgaggagcc caggttcgtc gaaccagttc aggaccttgg
    19621 ggtcagggtg ccaggcagcg agctgacgta tgcacgtgac cttgggactg gcctgcaggt
    19681 gggcatcgat cagggtgccg cagtgcgggt cggtggggtt cgcgtgcgcc gtgatcgcga
    19741 ccaggtccgg tagaccgtca ctgccccagg gaagggagat cagccacttg gtctcctcca
    19801 ccggcgccag cggctccttg ccctgccatc ccgcctccac atgcacgagg gcgacgacgg
    19861 gcgctcctac gaccttggcg accccctcgg cgtcagcggc gtactgttcg ggcaggaagg
    19921 gctgtgccac gtacctcgga gtcaggatga gctgccgctg cttcaccggc gccagcttgc
    19981 cgaatgcctt ctcgaccagg tgcggtgccg cccggtagaa cttcgccgcg ggactggcct
    20041 ggcgcggcgt cgtaaaggga tcccattggt ggacgtgggt gtcgatgatc ccatcgacaa
    20101 cgcccgcgag actgtgtgtc attgcccttt tctcctctga agtgtcctgg cacgttctcc
    20161 tctgaagcgt tctggcaccg ttctcctctg aaatgttctg gcgcgtcacg tcgcaacagc
    20221 gagcgccgag ctgaagggct gtccaccaca acgtgatccc gcacgtgcgt tcctcgcgac
    20281 agcgcaccgg gccttgtccg tcccaggtgc tgatcgttcc ggtggcgcag tggatcaccg
    20341 cgccggtgcc ggtgagatca gcgtggtgga gccgtgtact gcttgctgct gtcgacgacc
    20401 gccgtgccca gcggcttgtc aatgtcgacg tcgagggtgc aggtgatgcg ggccatggtc
    20461 cagtagtagc cgacgaccag gatcacctcc acgatttcct tgtccgacag gtgcttggtg
    20521 agcggtacga agtcctcgtc atcgccccga ggccgctcca cgatgccggc ggcgaatccg
    20581 accagggcgc ggtcggcgtc ggacagagc
//
