LOCUS       NZ_CP096975            20879 bp    DNA     circular CON 12-MAY-2024
DEFINITION  Stenotrophomonas sp. NY11291 chromosome, complete genome.
ACCESSION   NZ_CP096975
VERSION     NZ_CP096975.1
KEYWORDS    RefSeq.
SOURCE      Stenotrophomonas sp. NY11291
  ORGANISM  Stenotrophomonas sp. NY11291
            Bacteria; Pseudomonadota; Gammaproteobacteria; Lysobacterales;
            Lysobacteraceae; Stenotrophomonas.
REFERENCE   1  (bases 1 to 4961805)
  AUTHORS   Zhou,D.
  TITLE     Complete sequence of chromosome of strain NY11291
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 4961805)
  AUTHORS   Zhou,D.
  TITLE     Direct Submission
  JOURNAL   Submitted (02-MAY-2022) State Key Laboratory of Pathogen and
            Biosecurity, Beijing Institute of Microbiology and Epidemiology,
            No.20, Dongdajie, Fengtai, Beijing, Beijing 100071, China
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: HGAP v. v3.0
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 100.0x
            Sequencing Technology             :: PacBio RSII
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_023277365.1-RS_2024_05_12
            Annotation Date                   :: 05/12/2024 15:25:21
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 4,618
            CDSs (total)                      :: 4,528
            Genes (coding)                    :: 4,492
            CDSs (with protein)               :: 4,492
            Genes (RNA)                       :: 90
            rRNAs                             :: 5, 4, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 5, 4, 4 (5S, 16S, 23S)
            tRNAs                             :: 73
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 36
            CDSs (without protein)            :: 36
            Pseudo Genes (ambiguous residues) :: 0 of 36
            Pseudo Genes (frameshifted)       :: 11 of 36
            Pseudo Genes (incomplete)         :: 22 of 36
            Pseudo Genes (internal stop)      :: 6 of 36
            Pseudo Genes (multiple problems)  :: 2 of 36
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 04:39:31
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 3417564
            Orig. end                         :: 3438443
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP096975.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..20879
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene-precursor"
                     /region_number="6"
                     /rules="(PT_FPPS_like and not PT_HPP)"
                     /tool="antismash"
     cand_cluster    1..20879
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_FPPS_like and not PT_HPP)"
                     /kind="single"
                     /product="terpene-precursor"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..20879
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:10879](+)"
                     /cutoff="10000"
                     /detection_rule="(PT_FPPS_like and not PT_HPP)"
                     /neighbourhood="10000"
                     /product="terpene-precursor"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..10879
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="(PT_FPPS_like and not PT_HPP)"
                     /neighbourhood="10000"
                     /product="terpene-precursor"
                     /protocluster_number="1"
     misc_feature    complement(54..68)
                     /note="TFBS match to IolR, Regulator of the inositol
                     catabolism, confidence: medium, score: 19.2"
                     /tool="antismash"
     gene            complement(494..1738)
                     /locus_tag="M1L61_RS16020"
                     /old_locus_tag="M1L61_16020"
     CDS             complement(494..1738)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005410514.1"
                     /locus_tag="M1L61_RS16020"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="M1L61_16020"
                     /product="DUF418 domain-containing protein"
                     /protein_id="WP_235651927.1"
                     /transl_table=11
                     /translation="MADLPDGCPVNAASPSLQPMASGERIALLDVLRGAALLGILLMNI
                     EAFSGPLDLAFTGIDTHWQGIDYWADAFVYVFVQGKFFTLFSLLFGAGFAVMAQRAEAA
                     GRDFTPFYLRRSAGLLLIGLCHALLVWSGDILVMYALVSLPLLACREAPRSWLPWMGVT
                     VYLGGIAMMLLVGAMVSMASTEDVQKMLADAQQSIELQRLVYGHGSWMQANAQRLSEFG
                     TSMGALLITGPEVLGMFLIGSWFAGSGALAAPERFPRLYATLRWIALPLGLLVTLIGVA
                     WKPYLAPGAYNLPVTAAMALVTIGGLPMCLGYLAWIVHWRARLAWLAPVGRMALTHYLG
                     QSLLCTWVFYHYGLGAFEMMPRSVQLLFALLLFAVQVALSHVWLRRFRFGPMEWLWRAM
                     TYRQWPPMRREAGQG"
     gene            complement(1838..2320)
                     /locus_tag="M1L61_RS16025"
                     /old_locus_tag="M1L61_16025"
     CDS             complement(1838..2320)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010482989.1"
                     /locus_tag="M1L61_RS16025"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="M1L61_16025"
                     /product="peptidylprolyl isomerase"
                     /protein_id="WP_010482989.1"
                     /transl_table=11
                     /translation="MKIEKDRVVRFHYTVSEVGQEPIESSKDRGEPLAILIGHGNIIPG
                     LENAMMDKEAGATFSVDVTAADAYGERREGLSQRVPKKHFGNTKLAPGQQVVLQTNFGP
                     RAVTVQKVGMSVVDVDLNHPMAGKDLHFDVEIVDVREAGKEEIDHGHVHGDGGHHH"
     gene            2394..2972
                     /locus_tag="M1L61_RS16030"
                     /old_locus_tag="M1L61_16030"
     CDS             2394..2972
                     /GO_function="GO:0008233 - peptidase activity [Evidence
                     IEA]"
                     /GO_function="GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /GO_process="GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005414114.1"
                     /locus_tag="M1L61_RS16030"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="M1L61_16030"
                     /product="C40 family peptidase"
                     /protein_id="WP_187296438.1"
                     /transl_table=11
                     /translation="MTANPKVAHYPEIMHITPVSSGLRRLLAPALLLALPVLMTACGGG
                     KAPRPAPPPSTANWPKTVPDNPEAANSVLMRAISLVGTPYRYGGNTPDSGFDCSGLVAY
                     VYREMLDLRLPRTSRDLAAVQGPKIDPQRLATGDLVFFGSRGSVTHVGIYVGEGRFVHA
                     PSTGGTVRLDSLSGPYWKDHYTGAKRVLR"
     misc_feature    complement(2998..3013)
                     /note="TFBS match to CRP, Cyclic AMP receptor protein,
                     confidence: medium, score: 17.13"
                     /tool="antismash"
     misc_feature    3081..3090
                     /note="TFBS match to ToxT, Regulator of MSHA biosynthesis,
                     confidence: weak, score: 14.63"
                     /tool="antismash"
     misc_feature    complement(3093..3108)
                     /note="TFBS match to AfsQ1, Two-component system AfsQ1-Q2,
                     activator of antibiotic production, confidence: strong,
                     score: 19.52"
                     /tool="antismash"
     gene            3170..3877
                     /locus_tag="M1L61_RS16035"
                     /old_locus_tag="M1L61_16035"
     CDS             3170..3877
                     /GO_function="GO:0008233 - peptidase activity [Evidence
                     IEA]"
                     /GO_function="GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /GO_process="GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003475603.1"
                     /locus_tag="M1L61_RS16035"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="M1L61_16035"
                     /product="C40 family peptidase"
                     /protein_id="WP_134958098.1"
                     /transl_table=11
                     /translation="MLGLALCLTSLPAWSQTAPNRSDVTPAPVAESTARPATKAEAAAP
                     QRSRVDAAASATLAALLPHLAANDTIPLMDRSAVVAGDLSRLLANYDTSSAANGSVVGT
                     AADNGKVQSLLRRAMTLLGTPYRWGGSNPDSGFDCSGLVGYVFRSALGIELPRVSREMA
                     HDDNAELINDRTALAAGDLVFFGRKGRVDHVGIYVGDGRFLHAPSSGKDVRVDTLLSGY
                     WGNKFMQARRVDL"
     gene            complement(4137..5471)
                     /locus_tag="M1L61_RS16040"
                     /old_locus_tag="M1L61_16040"
     CDS             complement(4137..5471)
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1212:
                     sodium:dicarboxylate symporter"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019660634.1"
                     /locus_tag="M1L61_RS16040"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="M1L61_16040"
                     /product="dicarboxylate/amino acid:cation symporter"
                     /protein_id="WP_019338617.1"
                     /transl_table=11
                     /translation="MKLVSAWLRIPFWQRVVGGFVLGALAGWALGPAAETWFGPLGELY
                     VTLIKMIAVPLVFFAVINAISSLHGQKSVAALSGRTFLWFVITAALAVCVGLGVGTVLQ
                     PGAGGLQLTMASNYVPREVPSVVQVLLDVVPANVFYALSGIGTKVNAAGETVLAAGRGS
                     ILPVIFFAGLVGFAIVKLGEKVTEARKLVGQMSDIMIQVTRFVLEVTPIGTFGLIAGLV
                     GSYGFEKLLPLGHFVLALYVACALHIVVVYSALLLAHGLNPLKFFRGAAPGMQVAFVSS
                     SSFAAMPVALRSITHNLGVNKDYGSFAVPLGASIKMDGCGAIYPALCAVFISQYSGVPL
                     TPEQYVVVLIASVLGSFGTAGVPGTAVIMATVVLSAANLPLETIGYLYAIDRILDMMRT
                     MTNVTGQMLVPVIVAKETGLLDQAVYDNPSSNVGVDDPDPTPPRA"
     gene            5626..7332
                     /locus_tag="M1L61_RS16045"
                     /old_locus_tag="M1L61_16045"
     CDS             5626..7332
                     /EC_number="3.1.3.1"
                     /GO_function="GO:0016791 - phosphatase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019660635.1"
                     /locus_tag="M1L61_RS16045"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="M1L61_16045"
                     /product="alkaline phosphatase"
                     /protein_id="WP_057502494.1"
                     /transl_table=11
                     /translation="MRRSVSLLAACATTLLLGACASTAPASAPAGLKVAVDPVTHPAGE
                     TPQWWYRSGAAQAAANGAMSGKARNVILFLGDGMSLTTVAASRIYEGQQKGGSGEENLL
                     SWERFPATAFSKTYNTDSQTPDSAGTMTAITTGVKTHMGAIGVSAGSRTDCADSLSKGL
                     LTWLQLADSAGLATGVVSTARLTHATPAATYAHSPERNWENDTDLTEAAKAAGCKDIAQ
                     QLLSTSRYGRGPLVALGGGRGEFTTVEERDPEYDDKVGQRLDGRSLVQEWQQAHPQGAY
                     VWNSKQLAAAANAPAILGLFEPDHMRYEYERPQDPGGEPSLAELTAAAIRNLSKHQEGY
                     VLMIEGARIDHANHSGNAYRALTETVALSDAVRVANELTSADDTLIIVTADHSHTLNFV
                     GYPARGNPILGKVKDKGGEDGAGKLDYALDGTGQPYTTLSYANGPGHTGSSNQQPAGPK
                     RYPHNPSSFEPANGRPNLREVDTEHPDYMQEALVPMKSESHGGEDVGIWARGPGSKAIR
                     GTLEQNAIYHMIVQATPALRERLCQAGTCDDKGVPVQLPAPTAFERKAEAK"
     gene            7329..7874
                     /locus_tag="M1L61_RS16050"
                     /old_locus_tag="M1L61_16050"
     CDS             7329..7874
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019660636.1"
                     /locus_tag="M1L61_RS16050"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="M1L61_16050"
                     /product="WG repeat-containing protein"
                     /protein_id="WP_248853773.1"
                     /transl_table=11
                     /translation="MIALQARPAPASGRFARSLALLGVLVSANALAQAPACKLLTDEHG
                     LWPLPNCEVVDHRPKIQPDTLKDLNFDDHGLAVVYADQGFHYVDRKGRSLPVLTWDNGP
                     EMPEEGLLRGRVGNRVGYFDLTFRQVVPGTFDFAWPFRGGVAEVCNGCRRGTPDADGHT
                     PMEGGERFRIDRSGRRVK"
     gene            8428..9714
                     /gene="tilS"
                     /locus_tag="M1L61_RS16055"
                     /old_locus_tag="M1L61_16055"
     CDS             8428..9714
                     /EC_number="6.3.4.19"
                     /GO_function="GO:0016879 - ligase activity, forming
                     carbon-nitrogen bonds [Evidence IEA]"
                     /GO_process="GO:0006400 - tRNA modification [Evidence IEA]"
                     /codon_start=1
                     /gene="tilS"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005418067.1"
                     /locus_tag="M1L61_RS16055"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="M1L61_16055"
                     /product="tRNA lysidine(34) synthetase TilS"
                     /protein_id="WP_029550871.1"
                     /transl_table=11
                     /translation="MTAFPALVPLDAPLLVGYSGGVDSTVLLHWLWRCAQASGTALRAV
                     HVHHGLQPAADDWVRHCQQQCAALGVKLAVRHVQIDRTTGLGLEGAAREARRAAFTAEL
                     REGETLALAQHQDDQAETFLLRALRGSGVDGLAAMADDSQFGTHRLWRPLLHVPRTALL
                     DYARQHALRWIEDPSNAEDHADRNFLRLQVLPLLRQRWPHAAAALAGSVLHCRQTRELL
                     DEEDAELITHLEVAPRVLSLQLLRQVSPGRAARVLRAWVIGHGAAPLPATVLQQGLDEL
                     LPAGNDRQARVRWHDHAIQQWREHAYLLPAQLPSLPRAWQAEWDGHAPLPLPDGGQLRL
                     QGGAAFERPLQVRARVGGERILLPGRQHSHALKDCLQREHLAPWRRAQLPLIFDGPQLL
                     AAADVVISAPLQAWLQAHQAQLQWRPGGW"
     gene            9751..10011
                     /locus_tag="M1L61_RS16060"
                     /old_locus_tag="M1L61_16060"
     CDS             9751..10011
                     /EC_number="3.1.11.6"
                     /GO_component="GO:0009318 - exodeoxyribonuclease VII
                     complex [Evidence IEA]"
                     /GO_function="GO:0008855 - exodeoxyribonuclease VII
                     activity [Evidence IEA]"
                     /GO_process="GO:0006308 - DNA catabolic process [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005410522.1"
                     /locus_tag="M1L61_RS16060"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="M1L61_16060"
                     /product="exodeoxyribonuclease VII small subunit"
                     /protein_id="WP_019338620.1"
                     /transl_table=11
                     /translation="MAKKSPENASPVAQFEQSLESLEQLVEQMETGELSLEASLSAYER
                     GVGLYRQCQQALEQAELRVRLLSDPAQPEASEPFDPPNHDG"
     gene            10001..10879
                     /locus_tag="M1L61_RS16065"
                     /old_locus_tag="M1L61_16065"
     CDS             10001..10879
                     /EC_number="2.5.1.10"
                     /GO_function="GO:0004337 - geranyltranstransferase activity
                     [Evidence IEA]"
                     /GO_process="GO:0008299 - isoprenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene-precursor: PT_FPPS_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1182: Polyprenyl synthetase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008264747.1"
                     /locus_tag="M1L61_RS16065"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="M1L61_16065"
                     /product="farnesyl diphosphate synthase"
                     /protein_id="WP_019338621.1"
                     /sec_met_domain="PT_FPPS_like (E-value: 6.8e-65, bitscore:
                     217.1, seeds: 145, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTAEVLFARWRDRIESQLDAALPSPAEAPQRLHQAMRYSVLGGGK
                     RMRPLLVYASGHLFGAQLESLDAAAMSVELIHAYSLVHDDLPAMDDDALRRGKPTTHIA
                     FDEATAILAGDALQTRAFGLLADAPLPATLRVACLQTLAHASGASGMCGGQALDIDATG
                     QQQTLAALTRMHALKTGALIRAAVRMGALCGQAHEPQLAQLDSFADALGLAFQVRDDIL
                     DVEASSEQLGKTAGKDQAQDKSTFPALLGMDGAKAQLHELAARMQSILAGYGEEADALR
                     ALATLAVERDH"
     gene            complement(10965..11336)
                     /locus_tag="M1L61_RS16070"
                     /old_locus_tag="M1L61_16070"
     CDS             complement(10965..11336)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014647933.1"
                     /locus_tag="M1L61_RS16070"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="M1L61_16070"
                     /product="DUF4870 domain-containing protein"
                     /protein_id="WP_010482972.1"
                     /transl_table=11
                     /translation="MSEFDNVPPPPATTDVPADQRTMALAAHLLGIFTGFIGALIIWLI
                     NKDDAGKAFVTDQAKEALNFQITVTIAMVISMILTIVIIGVFLAPIVGIISLVFSIIAA
                     VKANNGEAYRYPFALRLIK"
     gene            complement(11424..12791)
                     /gene="pmbA"
                     /locus_tag="M1L61_RS16075"
                     /old_locus_tag="M1L61_16075"
     CDS             complement(11424..12791)
                     /EC_number="3.4.24.-"
                     /GO_function="GO:0008237 - metallopeptidase activity
                     [Evidence IEA]"
                     /GO_process="GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /gene="pmbA"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019662101.1"
                     /locus_tag="M1L61_RS16075"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="M1L61_16075"
                     /product="metalloprotease PmbA"
                     /protein_id="WP_049411897.1"
                     /transl_table=11
                     /translation="MNVIAPEVAVGDDSPARLERLADLSQQLLDRARALGASQAEVSCS
                     EDRGLEVNVRLGEVETVQSTRDRGIAVTVYFGQRKGSASTGDLNEASLTATVEQACAIA
                     RHTEDDPAAGLAEAALMATDFPDLDSWHPWALQADEAVDLALACENAGREADAQIRNSD
                     GASVSSMQSLSVYANSHGFFGRERGTHHSVGCALIAGQGDGMQRDGWYTSALAREDLEE
                     VGLVGRRAAERTVARLQPRSMATGSMPVLFAPEVARSLVGHLLSAVSGGALYRQASFLL
                     DSVGQQLFPDWMQIEELPHLRRGLRSAAFDGDGVATRASALVRDGVLQRYVLGSYSARK
                     LGLQTTANAGGVHNLQLAANAGSLQEIARQMGDGLLVTELMGQGVNGVTGDYSRGAGGF
                     RVENGEIQYPVDGITIAGNLREMFSSIEAVGSDVDPRSHIRTGSILLGRMTIAGND"
     misc_feature    12835..12844
                     /note="TFBS match to ToxT, Regulator of MSHA biosynthesis,
                     confidence: weak, score: 14.42"
                     /tool="antismash"
     misc_feature    12836..12849
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 14.54"
                     /tool="antismash"
     gene            12860..13447
                     /gene="yjgA"
                     /locus_tag="M1L61_RS16080"
                     /old_locus_tag="M1L61_16080"
     CDS             12860..13447
                     /GO_process="GO:0042254 - ribosome biogenesis [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="yjgA"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017355121.1"
                     /locus_tag="M1L61_RS16080"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="M1L61_16080"
                     /product="ribosome biogenesis factor YjgA"
                     /protein_id="WP_010482967.1"
                     /transl_table=11
                     /translation="MRGRDEETGEFHDKSRSQNRRDALDVLALGEKLVSLTPAQLARLP
                     IPEDLLPHIAECKRITAHIAHKRQLAFLAKHMRREEDATLDAIRDALDANSETGRREVA
                     MMHRAEDWRERLLAEGDKALAALLDDYPQADRQQLRTLVRNAQAEKAKNKPPRAYREIF
                     QVLRALMLPAALGLKASAEDADPIETDEADED"
     gene            complement(13489..14934)
                     /gene="tldD"
                     /locus_tag="M1L61_RS16085"
                     /old_locus_tag="M1L61_16085"
     CDS             complement(13489..14934)
                     /EC_number="3.4.24.-"
                     /GO_function="GO:0008237 - metallopeptidase activity
                     [Evidence IEA]"
                     /GO_process="GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /gene="tldD"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007972594.1"
                     /locus_tag="M1L61_RS16085"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="M1L61_16085"
                     /product="metalloprotease TldD"
                     /protein_id="WP_159360420.1"
                     /transl_table=11
                     /translation="MTDIALTLAQDRLLRPGGLDTAGLERTFGQLLGPGVDFGDLYFQH
                     ARRESWSVEDGIVKDGAHSIEQGVGVRAISGEKTGFAYSDDIHADALRVAAQSARAISR
                     EGGAQTGRSLLRGNARALYPALDPIDGIGNEAKVEVLKRLDGYLRAADPRVKQVMVSLS
                     GGVDTVLIARSDGVLGADVRPLVRLNVQVIVEHNGRRESGYAGGGGRYGYEELFADGRP
                     EAFAREALRQALVNLEAVPAPAGVMPVVLGPGWPGVLLHEAVGHGLEGDFNRKGTSVYA
                     GRIGERVAAPGVTIVDDGTLDGRRGSLNIDDEGHPSQCTTLIEDGILVGYMQDSLNARL
                     MGVAPTGNGRRESFAHMTMPRMTNTYMRAGQHDPQEMIRSVKKGLYAVNFGGGQVDITS
                     GKYVFSATEAYLIEDGRITTPVKGATLIGNGPETMQKVRMVGNDLALDEGVGICGKDGQ
                     SVPVGVGQPSLLIEGITVGGTQA"
     misc_feature    14930..14944
                     /note="TFBS match to MexT, Global virulence regulator,
                     confidence: weak, score: 16.64"
                     /tool="antismash"
     misc_feature    14937..14951
                     /note="TFBS match to SypG, Regulator of biofilm formation
                     and host colonization, confidence: weak, score: 17.56"
                     /tool="antismash"
     gene            complement(14995..18849)
                     /locus_tag="M1L61_RS16090"
                     /old_locus_tag="M1L61_16090"
     CDS             complement(14995..18849)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014647937.1"
                     /locus_tag="M1L61_RS16090"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="M1L61_16090"
                     /product="YhdP family protein"
                     /protein_id="WP_248853774.1"
                     /transl_table=11
                     /translation="MSAPPRLRLRRIRRHFIAACAVGLVGLALLVGTLSQLLPLAERHP
                     DRIAAWLSERAGQPVRFDQLQTAWTRRGPLLQLKGLRIGAGQGLAISEAEVLVSMYSGL
                     LPGRSLTELRLRGLALDLQQGEDGRWSVRGLPQAANGGDPLDALRRLGELQVIGGRLGV
                     HAPGLGIDTTLPRIDVRLRVNGDRLRVGVRAWAQTEALPLTAVLDVDRVRGNGQAWLGA
                     DPVDFHAWSPLLAAGGVRLREGKGELNLWLTLRDFAPVAVTTDSDLRDVRIDGAPMPAM
                     AAPQLQLQRLQARLRWQRQADGWALQVPRLRLKTEEGEQQLDGLQLQLGKQMRVSSREV
                     QAGIALRALALSDRLEPGLRRWLFLSRPQLDVRELQLAGERDGPLWAQGELQSLGFASV
                     GNSPGLRGLGGRFEGDADGFSLQLQSQRQLQFDWPTGFGVRHDLHLAGQVVGWRDEGGG
                     WRIGTAAMRVEGTDYAADVRGGVWFQGDGTRPWLQLAAKLDDVPMTAAKRFWIHSKMSK
                     GATDWLDMALAGGQVRNGIGLVSGDLDDWPFDNNDGRFEATGHITNGDIRFQHDWPLMR
                     QVDADIAFIGPGFDMHGRGDLAGVAVQKFEAGIQDFGQQPLYVRADAQSEAGRLLAMLR
                     QSPLHKDYGDTLDNLTAAGPAHVTFDLLQPLHHDEGGGHLQGTVDLAGVKLVDKRFQLT
                     FDNMHGQARYSNGGFGAEELAVRHLGQDGRLSLRAGGYVHDSKLAFESQLSANLDAGVL
                     IDRAPEMAWLKPYIAGTSPWTIAVNLPKVAPGAPAPPSELRLSSDLVGTRLDLPAPLDK
                     PAAEPLATTVAAQLPMGAGRIDVSFGQRLALAARSHNNQTGVQVTLGSDHADREPPPSG
                     LSVNGRSPTLDALEWIGLARGGNDDDGMPLRAVDVQVGKLMLIGGVFEQTRLQLRPGAQ
                     ALDVRLDGPSLAGRLTVPNADGGTISGQLDRVHWQSLPAAPGVPAAPARVQAGANDMDP
                     AKLPPFALDIADLKFGKVVLGQAVLRTRPLANGLNVDELRFRAPDQEIDISGRWLGRTG
                     GARTELTAQVRSEDLGGLMQNLDYGGQLRGGSGQAQLQATWSGGPSDFQLGNLQGRLDL
                     HARNGQLLELEPGAGRVLGLLSVTQLPRRLMFDFRDFFSKGFAFNQIDGSMQFGQGMAR
                     TDKVLIEGPAANITIRGQADLRNQQFDQTIDVNPRAGNLLTVVGAVAGGPVGAALGAAT
                     NAVLSKPLGEIGARTYKVTGPWKEPKVEVIERSRDKAPPPAPAPAPAIPPTVTGLPRAR
                     "
     gene            complement(18880..20367)
                     /gene="rng"
                     /locus_tag="M1L61_RS16095"
                     /old_locus_tag="M1L61_16095"
     CDS             complement(18880..20367)
                     /EC_number="3.1.26.-"
                     /GO_function="GO:0003723 - RNA binding [Evidence IEA]"
                     /GO_function="GO:0004540 - RNA nuclease activity [Evidence
                     IEA]"
                     /GO_process="GO:0006396 - RNA processing [Evidence IEA]"
                     /codon_start=1
                     /gene="rng"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002802933.1"
                     /locus_tag="M1L61_RS16095"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="M1L61_16095"
                     /product="ribonuclease G"
                     /protein_id="WP_049454682.1"
                     /transl_table=11
                     /translation="MSEEILVNVTPRETRVAVIENGMLQELHIERGWRRGVVGNIYKGK
                     VQRVMPGMQAAFVEVGLERAAFLHANDVVRPAPVASADTENTTLPPPSSVPIVELLRDG
                     QDIVVQVVKDPIGTKGARLTTQISIPSRYMVLLPQSKVVGVSARIEDETERARLKALVT
                     ELSAQHGGYGYIVRTNAEGQPAEAIAEDIAYLSRVWNVVERRGREAASCSNIYEDLSLP
                     LRSVRDLIRKDVDKVKVDSKETFAQLQAFVAKYMPVLAEKIELYSGDRPIFDMFGVEDE
                     IGRALDKQVPLKSGGYLVIDQTEAMTTIDVNTGSFLGQRNLEETVFRTNLEAAQSVARQ
                     LRLRNLGGIIIIDFIDMDDAEHRRQVLRTLEKALARDHAKTTVYDFSPLGLVEMTRKRT
                     VESLERQLSETCPQCSGRGSIKTTETVTYEIFREITRAVRQFDAARLLVIASTKVVARI
                     TDEESAAVAELEEFLGKSIRFQADEQYLQEQFDVVLL"
ORIGIN
        1 gcgcgttcag cgcctcacac tcggctgcat ggtgatcgaa attgcgggcg tcaccgaaca
       61 catagtccag accgcgcgcc tcgaactcgc agtccagcgc atgcgtccgc acccactgcg
      121 ccaggcgcag ccgtgaatca ttcaacagtg cgccgcgtgc ccgcgtggag tgcagccagt
      181 cacgcgcgtt gcagcgcgcc ccgaactgca gcagccagcg ccacaatgca gggtcgaggc
      241 gtgtacggac gtacagcggc gcacgcggat cgagcatcca gcgcagcgcc cgtaacggca
      301 caccaggcgc tgccagcggt ggcgcgtggc tgggggtgat ggtgccgcag ttgccatgcg
      361 aagtcgccgc acccacgcgt ccccgctcga tcatacggac ctgccggccg ttcgcgcaca
      421 gcgcaagcgc ggtggccagg ccgatggcac cggcgcccac cacgatcaca tcctcgcgcg
      481 cgccctgcat cgatcagccc tgcccggcct cgcgccgcat cggcggccac tgccggtagg
      541 tcatcgcgcg ccacaaccat tccatcgggc caaagcggaa gcggcgcaac cagacgtgtg
      601 aaagggccac ctgcacggca aacaacagca gtgcgaacag cagctgcacg ctgcgtggca
      661 tcatttcgaa cgcgcccagg ccgtagtggt agaacaccca ggtgcacagc agcgactggc
      721 ccaggtagtg ggtcaacgcc atgcgcccga ccggtgccag ccaggccaac cgcgcacgcc
      781 aatgcacgat ccacgccagg tagcccaggc acatcggcag gccaccgatc gtcaccagtg
      841 ccattgcggc tgtcaccggc agattgtagg cacccggtgc aaggtagggt ttccaggcaa
      901 caccgatcaa cgtgaccagc aggcccagcg gcaacgcaat ccagcgcagc gtcgcgtaca
      961 gccgcgggaa gcgctccggc gccgccagcg cgccactgcc ggcaaaccag ctgccgatca
     1021 ggaacatgcc cagcacctcc gggccggtga tcagcagcgc gcccatcgac gtgccgaact
     1081 cgctcagccg ctgcgcattg gcctgcatcc agctgccgtg cccgtacacc aggcgctgca
     1141 gctcgatgct ctgctgcgcg tcggcgagca tcttctgtac gtcttccgtc gaagccatcg
     1201 acaccatcgc gcccaccagc agcatcatcg ctataccgcc gaggtagacc gtcacgccca
     1261 tccacggcag ccagctgcgc ggcgcctcgc ggcaggccag cagcggcaac gagaccagcg
     1321 cgtacatcac caggatgtcg ccggaccaga ccagcagcgc gtggcacagg ccgatcagca
     1381 acaggccggc gctgcggcgc aggtagaacg gggtgaagtc gcgcccggcg gcctcggcgc
     1441 gctgcgccat caccgcgaag ccggcgccga acagcaacga gaacagggtg aagaacttgc
     1501 cctgcacgaa cacgtagacg aacgcatcag cccagtagtc gatgccctgc cagtgcgtgt
     1561 cgatgccggt aaaggccagg tccagcggtc cgctgaaggc ctcgatgttc atcagcagga
     1621 tgcccagcaa cgccgcaccg cgcagcacgt ccagtagggc gatgcgttcg ccggaagcca
     1681 tcggctgcag ggaaggagaa gcggcgttca cggggcatcc gtcaggcagg tccgccatta
     1741 tgccgccggc ccacacgcca tggatggccg cgtcgtgttc cagaaacgca acggcccgcc
     1801 gaagcgggcc gttgctgcca tcacgatcgc gctgcgatca gtggtggtgg ccgccgtcgc
     1861 cgtggacgtg gccgtggtcg atctcttcct tgccggcttc acgcacgtca acgatttcga
     1921 cgtcgaaatg caggtccttg ccagccatcg ggtggttcag gtcgacgtcg acgacgctca
     1981 tgccgacctt ctgcacggtc accgcacgcg ggccgaagtt ggtctgcagc acgacctgct
     2041 ggcccggggc cagcttggtg ttgccgaagt gcttcttcgg cacgcgctgg gacaggccct
     2101 cgcggcgctc gccgtaggca tcagcggcag tgacgtcgac gctgaaggtc gcgccggctt
     2161 ccttgtccat catggcgttt tccaggcccg ggatgatgtt gccgtggccg atcaggatcg
     2221 ccagcggctc gccgcggtcc ttggacgatt cgatcggctc ctggccgact tcggaaacgg
     2281 tgtagtggaa gcggacaacg cggtcttttt cgatcttcat gcgcaactct gtctggatct
     2341 gccgaaggca ggcgggttgg ggcgggttgt cgcccggcgg ggacgccgcc atcatgacgg
     2401 ccaatcctaa ggtggcgcat tatccggaga tcatgcacat cacgccagtt tcgtccggcc
     2461 tgcgccggct cctcgccccg gccctgctgc tggccctgcc cgtgctgatg accgcctgcg
     2521 gcggcggcaa ggccccccgc cccgcgcccc ccccgtcgac ggcgaactgg ccaaagaccg
     2581 tgccggacaa ccccgaggcg gccaactcgg tgctgatgcg cgccatcagc ctggtcggca
     2641 cgccctaccg ctatggcggc aacaccccgg attcgggctt cgactgcagc ggcctggtcg
     2701 cctatgtcta tcgcgagatg ctggacctgc ggctgccgcg cacctcccgc gacctggcgg
     2761 cggtacaggg accgaagatc gacccgcagc gcctggccac cggagacctg gtgttcttcg
     2821 gcagccgcgg cagcgtcacc catgtcggta tctatgtggg tgaagggcgc ttcgtgcacg
     2881 cgccgagcac cggcggcacg gtacgcctcg actcgctcag cggtccctac tggaaggacc
     2941 actacacagg ggcgaaacgc gtccttcgct aaaatgaaca ggcgatatgt tcaaaactgt
     3001 gacgcccatc accacgaaac taacgattta ctaacggaat ttttaactta ttgccgcttt
     3061 tacagggcat gatgccccat cgtttttttc ctgtgaccga cgcgtgacga ctgacgacct
     3121 gaaaagcgaa ggccagactt ccgtatcttc acgtagtgcc cgcccgctgt tgcttggcct
     3181 ggcactgtgt ctgaccagcc ttccggcctg gtcgcagact gctccgaatc gttccgatgt
     3241 gaccccggcc ccggtggctg agagcaccgc ccgaccggcc accaaggccg aggccgctgc
     3301 tccgcagcgc agccgcgtcg atgccgccgc cagtgccacg ctggccgccc tgctgccgca
     3361 cctggccgcc aatgacacca ttccgctgat ggaccgctcg gccgtggtgg cgggcgatct
     3421 cagccgcctg ctcgctaact acgacaccag cagcgccgcc aatggcagcg ttgtcggcac
     3481 cgccgccgat aacggcaagg tgcagtcgct gctgcgccga gcgatgaccc tgctgggcac
     3541 cccgtaccgt tggggtggca gcaacccgga cagcggcttc gactgcagcg gcctggtcgg
     3601 ctacgtgttc cgctcggcgc tgggcatcga gctgccgcgc gtctcgcgcg agatggccca
     3661 cgatgacaac gccgagctga tcaacgaccg cactgcgctc gccgccggtg acctggtgtt
     3721 cttcggccgc aagggccgcg tcgaccacgt cggcatctat gtcggtgatg gccgcttcct
     3781 gcacgccccg agctcgggca aggacgtccg cgtggacacc ctgctcagtg gttactgggg
     3841 caacaagttc atgcaggctc gtcgggtcga cctctgaccc gctggcacta cggcgccgcc
     3901 tgaaagacaa aaagccgctg ccccgcagcg gcttttttgt ttgcgccccc ggtaggtgcc
     3961 gaccttggtc ggcatcgcgc cgcctgccct ggtgggtgcc gaccgttggt cggcactgcc
     4021 tccatccacg catggcgtgg atctaccagg acccgccttg gccgccaccg cgccaaccag
     4081 ctcccaaaca aaaggcccgc cgggtcaggg cgggcctttt acatctccac gcaacctcag
     4141 gcgcgtggcg gtgtcgggtc tggatcgtcc accccgacat tgctggacgg attgtcatac
     4201 accgcctgat cgagcagccc ggtctccttg gccacgatca ccggcaccag catctggccc
     4261 gtcacgttcg tcatcgtgcg catcatgtcc aggatgcggt cgatggcata caggtagccg
     4321 atggtctcca gcggcaggtt ggccgcgctc agcaccaccg tggccatgat caccgcagta
     4381 cccggcacgc cggcggtacc gaagctgccc agcaccgagg cgatcagcac caccacatac
     4441 tgttccgggg tcagcggcac accgctgtac tgcgagatga acaccgcgca cagcgccggg
     4501 tagatcgcgc cgcagccatc catcttgatg ctggcgccca gcggcaccgc gaacgaaccg
     4561 tagtccttgt tcacacccag gttgtgggtg atcgaacgca gcgccaccgg catcgcggcg
     4621 aagctggacg agctgacaaa cgccacctgc atgcccggcg cggcgccacg gaagaacttc
     4681 agtgggttca ggccgtgcgc cagcagcagc gcgctgtaga ccaccacgat gtgcagggcg
     4741 caggccacgt acagggccag cacgaaatgc cccagcggca gcagcttctc gaagccgtag
     4801 ctgccgacca ggccagcgat caggccgaag gtgccgatcg gggtgacttc cagcacgaag
     4861 cgggtcacct ggatcatgat gtcgctcatc tggccgacca gcttgcgcgc ctcggtcacc
     4921 ttctcgccca gcttgacgat ggcgaaaccg accagaccag caaagaagat caccggcagg
     4981 atcgagccac ggcccgcggc cagcacggtt tcaccggcgg cgttgacctt ggtgccgatg
     5041 ccggacagcg cgtagaagac attggccggc accacatcca gcagcacctg caccacgctg
     5101 ggcacttcac gcggcacgta gttgctggcc atcgtcagtt gcaggccacc ggcgccgggc
     5161 tgcagcacgg tgcccacgcc caggccgacg cacaccgcca gcgcagcggt gatcacgaac
     5221 cacaggaagg tgcggccact gagcgcggcg accgatttct ggccgtgcag cgacgagatc
     5281 gcgttgatga ccgcgaagaa caccagcggc accgcgatca tcttgatcag ggtgacgtac
     5341 agctcgccga gcgggccgaa ccacgtttcc gcggccgggc cgagcgccca gccggccagc
     5401 gcgccgagca cgaagccacc gaccacgcgc tgccagaatg gaatccgcag ccaggcagag
     5461 accagcttca taggcaatcc agaggggaag gaagggatgg tggcacgata gcccaaggcg
     5521 gcccgcagaa cgaccgcccg gccggcaaat cagtgtgtca tcggcgtgcc ttgcgagggc
     5581 gggcataatg aacgtcccgt tacagtttgt gagatcccag cgtccatgcg ccgttccgtc
     5641 tccctgttgg ccgcctgcgc caccaccctg ctgctgggcg cctgcgccag caccgccccc
     5701 gcgtccgctc cggccggcct gaaggtcgcc gtcgatcccg ttacccaccc ggccggcgag
     5761 acgccgcagt ggtggtaccg cagcggcgcg gcccaggccg cagcgaacgg tgcgatgtcc
     5821 ggcaaggcca ggaacgtcat cctgttcctc ggtgacggca tgagcctgac cacggtggcc
     5881 gcctcgcgca tctacgaagg ccagcagaag ggtggctcgg gcgaagagaa cctgctgtcc
     5941 tgggaacgct tcccggccac ggcgttcagc aagacttaca acaccgattc gcagacccct
     6001 gattcggccg gcaccatgac cgccatcacc accggcgtga agacccacat gggcgcgatc
     6061 ggcgtcagcg ccggcagccg caccgactgc gccgacagcc tgtccaaggg cctgctgacc
     6121 tggctgcagc tggccgacag cgccggcctg gccacgggcg tggtgtccac cgcacgcctg
     6181 acccatgcca ccccggccgc cacctatgca cattcacccg agcgcaactg ggaaaacgac
     6241 accgacctga ctgaagcggc caaggcggca ggctgcaagg acatcgccca gcagctgctg
     6301 tcgacctcgc gctatggccg cggcccgctg gtcgccctcg gcggtggccg cggagaattc
     6361 accaccgtgg aagagcgcga tccggagtac gacgataagg tcggccagcg cctggacggc
     6421 cgcagcctgg tgcaggaatg gcagcaggcc catccgcagg gcgcctacgt ctggaacagc
     6481 aagcagctgg ccgccgccgc caatgcgccg gccatccttg gcctgttcga gccggaccac
     6541 atgcgctacg agtacgagcg accgcaggat ccgggcggtg agccgagcct ggccgaactg
     6601 acggctgcgg cgatcaggaa tctgtcgaag caccaggaag gctacgtgct gatgatcgaa
     6661 ggcgcgcgca tcgaccacgc caaccacagc ggcaacgcct accgtgcact gaccgagacc
     6721 gtggccctgt ccgatgcagt gcgcgtggcc aacgaactga cctcggccga cgacaccctg
     6781 atcatcgtca ccgccgacca ctcgcacacg ctgaacttcg tcggctaccc ggcacgcggc
     6841 aatccaatcc tgggcaaggt gaaggacaag ggtggcgaag atggcgccgg caagctggac
     6901 tacgcgctgg acggcaccgg ccagccgtac accacgttga gctacgccaa tggcccgggc
     6961 cataccggca gcagcaacca gcagccggcc ggcccgaagc gctacccgca caacccgagc
     7021 agcttcgaac cggccaacgg ccgcccgaac ctgcgcgagg tcgacaccga gcatccggac
     7081 tacatgcagg aagcactggt gccgatgaag tccgagtcgc acggcggcga agacgtcggc
     7141 atctgggcac gcggcccggg cagcaaggcg atccgcggca cgctggaaca gaacgcgatc
     7201 taccacatga tcgtgcaggc caccccggcc ctgcgcgagc gcctgtgcca ggccggcacc
     7261 tgcgatgaca agggcgtgcc ggtgcagctg ccggcgccga cggccttcga acgcaaggcc
     7321 gaggccaagt gatcgcactg caggcccgcc ctgcgcctgc cagcggccgc ttcgcgcggt
     7381 cgctggccct gctcggcgtg ctggtcagtg ccaacgcgct ggcgcaggca ccggcgtgca
     7441 agctgctgac cgacgaacac gggttgtggc cgctgcccaa ctgcgaagtg gtcgaccacc
     7501 ggccgaagat ccagccggac accctgaaag acctgaactt tgatgaccac ggcctggccg
     7561 tggtgtatgc cgaccagggt ttccactacg tcgaccgcaa gggccgcagc ctgccggtgc
     7621 tgacctggga caacggcccg gagatgccgg aagaaggcct gctgcgcggc cgcgtcggta
     7681 atcgcgtggg ctacttcgat ctgacattcc gccaggtggt gcccggcacc ttcgatttcg
     7741 cctggccgtt ccgcggcggc gtggccgagg tctgcaacgg ctgccgtcgc ggcacgccgg
     7801 atgccgatgg ccacacgccg atggaaggcg gagagcggtt ccggatcgac cgctcgggtc
     7861 gtcgggtgaa gtaggttttc ggcagggctg cgccctgcac ctgcagacgc aacggcaacg
     7921 gcaacggccg aagcaacagc aacagcgtgc attccgtggg atggcggggc actgtgggtt
     7981 tgcggggacg gcgcaagtac gtccatgtag ccttggtcgc cgcatccatg cggctcacac
     8041 cccgcaaacc cacagtgccc cgccttcgac agttttccgg tggccagtag atctacgcca
     8101 tgcctggatg aaatctgtca gatatcgaat tgaatccggg gtcagatccg ttttccgcag
     8161 gaaaacggat ctgaccccaa gagcaattcc gacagttcgc aggaaactgt cgaaggcggg
     8221 gtgggtccgg ttgcgggagt gtccgcggca tggatgccgc ggccaagccc ccatggatgg
     8281 gtttacggcg tctcccgcaa ccgggcccac cccgccatcc ttcaggaacc cagcttctgc
     8341 tgttgctgtt gctgttgctg ttgctgttgc tctggatcgt agcgggtgca gggcgcagcc
     8401 ctgccgagca accctatact tgccgccgtg actgccttcc ctgcccttgt tccgctggat
     8461 gcgccgctgc tggtgggcta cagcggtggt gtcgactcca ccgtgctgct gcactggctg
     8521 tggcgctgcg cccaggcttc cggcacggcg ctgcgtgcgg tgcacgtaca ccacggcctg
     8581 caaccagcag ccgacgactg ggtacggcat tgccagcagc agtgcgcagc actgggcgtc
     8641 aagctggccg tgcgccacgt acagatcgac agaaccacag gcctgggcct cgaaggcgca
     8701 gcgcgcgaag cacgacgtgc agcgttcact gctgaactgc gcgaaggcga aacactggcg
     8761 ctggcacagc accaggacga tcaggccgag accttcctgc tccgcgcgct gcgcggctcc
     8821 ggtgtcgatg gccttgccgc gatggccgat gacagtcagt tcggtacgca ccgcctgtgg
     8881 cgtcccttgc tgcacgtacc gcgcaccgca ctgctcgact atgcccggca acacgcgctg
     8941 cgttggatcg aggatcccag caacgccgaa gaccacgccg atcgcaactt cctgcgcctg
     9001 caggtactgc cactgttgcg ccagcgctgg ccgcacgccg ccgccgcgtt ggccggcagc
     9061 gtcctgcatt gccggcagac ccgcgaactg ctggatgaag aagacgccga gctgatcaca
     9121 cacctggaag tcgctccacg cgtgctgtcg ctgcagttgc tgcgtcaggt gtcaccggga
     9181 cgcgccgcgc gcgtgctgcg cgcctgggtg atcggccatg gtgccgcccc actgccggcc
     9241 acggtgctgc agcaaggcct ggacgaactg ctgccggccg gcaatgatcg ccaggcgcgg
     9301 gtgcgctggc acgatcatgc catccagcaa tggcgcgagc atgcctatct gctacccgcg
     9361 cagctgccat cgctgccccg cgcgtggcag gccgaatggg atgggcatgc tcccctgccg
     9421 ctgcccgatg gcggccagct gcggctgcag ggcggcgccg ccttcgagcg cccgctgcag
     9481 gtccgtgcac gcgtgggcgg agagcgcatc ctgctgccag gtcgccagca ttcgcacgca
     9541 ttgaaggact gcctgcaacg cgaacatctc gccccctggc gacgcgcgca gctgccgctg
     9601 atctttgatg gcccgcagtt gctggccgcc gccgacgtgg tcatctccgc gccactgcag
     9661 gcctggttgc aggcccacca ggcacagctg cagtggcgtc ccggcggctg gtgaattgac
     9721 ccccgcgcgc ggcccgtcca cacttgccac atggccaaga agtcccccga aaacgcctcc
     9781 ccggtcgccc agttcgagca gtcgctcgaa tcgctggaac agctggtgga gcagatggaa
     9841 accggcgagc tgagcctgga agcctcgctc agtgcttacg aacgtggcgt cggtctgtat
     9901 cgccagtgcc agcaggcgct ggagcaggcc gaactgcgcg tgcgcctgct cagcgatccg
     9961 gcgcagccgg aagcatccga gcccttcgat ccgcccaacc atgacggctg aggttctgtt
    10021 cgcgcgctgg cgcgaccgta tcgaaagcca gctcgacgct gccctgccct cgcctgccga
    10081 agcaccgcag cgcctgcacc aggccatgcg ctattcggtg ctgggcggtg gcaagcgcat
    10141 gcgcccgctg ctggtctacg ccagtggcca cctgttcggt gcacagctgg aaagcctgga
    10201 tgcggcggct atgtccgtcg aactcatcca cgcctactcg ctggtgcatg acgacctgcc
    10261 ggcgatggat gacgacgcgc tgcgccgtgg caagccgacc acccacatcg ccttcgacga
    10321 agctaccgcg atcctcgccg gcgacgcgct gcagacccgt gccttcggcc tgctggccga
    10381 tgcaccgctg ccggccacgc tgcgcgtggc ctgcctgcag accctggccc acgcctccgg
    10441 cgcgtccggc atgtgcggcg gccaggccct ggatatcgat gccaccggcc agcagcagac
    10501 gctggcggca ttgacccgca tgcatgcgct gaagaccggc gcgctgatcc gcgcggcagt
    10561 gcgcatgggc gcgctgtgcg gccaggccca cgaaccgcag ctggcccagc tggacagctt
    10621 cgccgatgca ctcggcctgg ccttccaggt acgggacgac atcctcgatg tcgaggccag
    10681 ttccgagcag ctgggcaaga ccgccggcaa ggaccaggcg caggacaaga gcacctttcc
    10741 cgccctgctt ggcatggacg gcgcaaaggc ccagctgcac gaactcgctg cacgcatgca
    10801 gtcgatcctg gccgggtatg gcgaggaagc cgatgcgctg cgtgcgctgg cgacgctggc
    10861 ggtcgaacgc gatcattgat cgctcgccgg gcaccgcccg tcgctccccg cacatgaaaa
    10921 cgcccggcaa tgccgggcgt tttcagttcc gcatgcagcc ggtattactt gatcaggcgc
    10981 agcgcgaacg ggtagcgata ggcttcgccg ttgttggcct tgaccgctgc gatgatgctg
    11041 aacaccaggc tgatgatgcc gacgatcggg gccaggaaga cgccgatgat cacgatggtc
    11101 aggatcatgc tgatgaccat ggcgatggtc acggtgatct ggaagttcag ggcttccttg
    11161 gcctggtcgg tcacgaaagc cttgccagca tcgtccttgt tgatcagcca gatgatcagt
    11221 gcgccgatga agccggtgaa gatgcccagc aggtgggcag ccagggccat ggtgcgctgg
    11281 tcggccggca cgtcggtggt ggccggcggc ggcgggacgt tatcgaattc gctcacgaca
    11341 aaactccttt tcattgggtg gtcttgaccc accagcacca agctggttgc gtcaggcggg
    11401 catagcttac gccatcgacg ccatcaatca ttaccggcga tggtcatccg ccccagcagg
    11461 atcgaaccgg tccggatgtg cgagcgcggg tcgacgtcgc tgccgaccgc ttcgatgctg
    11521 ctgaacatct cgcgcaggtt gccggcgatg gtgatgccat ccaccgggta ctggatctcg
    11581 ccattctcga cgcggaagcc gccggcaccg cgcgagtagt cgccggtcac cccgttcacg
    11641 ccctgcccca tcagctcggt caccagcagg ccatcgccca tctggcgggc gatctcctgc
    11701 agggagcccg cgttggcggc cagttgcagg ttgtgcacgc caccagcatt ggcggtggtc
    11761 tgcaggccca gcttgcgcgc cgagtagctg cccagcacat agcgctgcag cacgccgtca
    11821 cggaccaggg ccgaagcacg ggtggccacg ccgtcaccgt cgaaggcggc cgagcgcagg
    11881 ccacggcgca ggtggggcag ttcctcgatc tgcatccagt ccgggaacag ctgctggcca
    11941 acactgtcca gcaggaagct ggcctggcgg tacagggcac cgccggacac cgccgacagc
    12001 aggtgaccga ccaggctgcg cgcgacttcc ggggcgaaca gcaccggcat gctgccggtg
    12061 gccatcgagc gaggctgcag gcgggcgacg gtacgctcgg cggcacgacg accgaccagg
    12121 cccacctcct ccaggtcctc gcgggccagc gcgctggtgt accagccatc gcgctgcatg
    12181 ccatcgccct ggccggcgat cagcgcacag cccaccgaat gatgggtgcc acgctcacgg
    12241 ccgaaaaagc catgcgaatt ggcgtacacc gacaggctct gcatgctcga caccgaggcg
    12301 ccgtcggagt tgcggatctg cgcatcggcc tcacgacctg cgttctcgca ggccagggcc
    12361 aggtccaccg cctcgtcggc ctgcagcgcc cagggatgcc agctgtccag gtcggggaag
    12421 tcggtcgcca tcagcgccgc ctcggccagg ccggcggccg ggtcgtcctc ggtatggcgg
    12481 gcgatcgcgc aggcctgctc gaccgtggcg gtgaggctgg cctcgttcag gtcgccggtg
    12541 ctggcgctgc ccttgcgttg gccgaaatag acggtgacgg cgataccgcg gtcgcgggtg
    12601 gactgcacgg tctcaacctc gccaaggcgg acattgacct ccaggccacg gtcctcgctg
    12661 cagctgacct cggcctggct ggcgcccagc gcccgggcac ggtcgagcag ctgctgggaa
    12721 aggtcggcca gccgttccag ccgggccggg ctgtcgtcgc cgacagcgac ttcaggggcg
    12781 atcacgttca atgctttatc ctgtacgggt tgggcccggc ctcacgccgg gcgacttttt
    12841 ttgagatcag gtaggaacga tgcgcggacg cgacgaagaa accggtgaat tccacgacaa
    12901 gagccgcagc cagaaccggc gcgatgcgct cgacgtcctg gccctgggcg agaagctggt
    12961 gtcgttgacc ccggcccagc tggcgcgcct gccgattccg gaagacctgc tgccgcatat
    13021 cgccgagtgc aagcgcatca ccgcccacat cgcccacaag cgccagctgg cgttcctggc
    13081 caagcacatg cgccgcgaag aagacgccac gctggatgcg atccgcgatg cgctggacgc
    13141 caacagcgaa accggccgcc gcgaagtggc gatgatgcac cgcgcggaag actggcgcga
    13201 gcgcctgctg gccgagggtg acaaggcact ggcggcactg ctggacgact acccgcaggc
    13261 cgaccgccag cagctgcgca cgctggtgcg caatgcccag gccgagaagg cgaagaacaa
    13321 gccgccgcgc gcctaccgcg aaattttcca ggtgctgcgt gccctgatgc tgccggccgc
    13381 gttgggcctg aaggccagcg ccgaagacgc cgaccccatt gaaaccgacg aagccgacga
    13441 ggactgagtc ctcgccggca ggggcggtgg cactggccat cgcccggctc aggcctgggt
    13501 accgccgacg gtgatgccct cgatcagcaa cgagggctgg ccgacaccca ccggcacgct
    13561 ctgcccgtcc ttgccgcaga tgcccacgcc ctcgtccagg gccaggtcgt tgccgaccat
    13621 gcgcaccttc tgcatggttt ccggaccgtt gccgatcagg gtcgcgccct tcaccggcgt
    13681 ggtgatgcgg ccatcctcga tcaggtaggc ctcggtggcc gagaacacgt acttgccact
    13741 ggtgatgtcg acctggccgc cgccgaagtt gaccgcgtac aggccctttt tcaccgaacg
    13801 gatcatctcc tgcgggtcat gctggccggc gcgcatgtag gtgttggtca tgcgcggcat
    13861 ggtcatgtgc gcgaacgatt cgcggcgacc attgccggtc ggcgccacgc ccatcaggcg
    13921 cgcgttgagg ctgtcctgca tgtagccgac caggatgccg tcctcgatca gcgtggtgca
    13981 ctggctggga tgaccctcgt cgtcgatgtt caacgaacca cggcgtccat ccagcgtgcc
    14041 gtcatcgacg atcgtcacgc ccggggcggc cacgcgttcg ccgatgcggc cggcgtagac
    14101 gctggtgccc ttgcggttga agtcgccttc caggccgtgg ccgaccgctt catgcagcag
    14161 cacgccgggc cagcccgggc ccagtaccac cggcatcacg ccggccggtg ccggtaccgc
    14221 ctcaagattc accagcgcct ggcgcagcgc ctcacgggca aaggcttccg ggcggccgtc
    14281 cgcgaacagt tcctcatatc cgtaacggcc accgccaccg gcatagccgg actcgcgacg
    14341 gccgttgtgc tcgacgatca cctgcacgtt caggcgcacc agcgggcgca cgtcagcgcc
    14401 cagcacaccg tcgctgcggg cgatcagcac cgtatcgacg ccgccggaca ggctgaccat
    14461 cacctgcttc acgcgcgggt cggcggcacg caggtagccg tccaggcgct tgagcacctc
    14521 gaccttggcc tcgttgccga tgccgtcgat cgggtccagc gccgggtaaa gcgcgcgcgc
    14581 gttgccacgc agcagcgagc gaccggtctg ggcaccacct tcgcgcgaga tcgcacgtgc
    14641 cgattgcgcc gccacccgca gcgcatcggc atggatgtcg tcggagtagg cgaaaccggt
    14701 cttctcgccg gaaatcgccc gcacgcctac gccctgctcg atggaatgcg cgccgtcctt
    14761 gacgatgccg tcttccacgc tccagctctc gcggcgggcg tgctggaagt aaaggtcacc
    14821 aaagtccaca ccggggccga gcaactgccc gaaggtgcgc tccaggccag cggtatccag
    14881 gccaccaggg cgcagcaggc ggtcttgggc aagcgtcagg gcgatatcag tcatggttct
    14941 cgatctgggg atgcgggggc gctcaggcaa gccccgtgaa caggaaagcc gcgctcaacg
    15001 cgcgcgcggc aggccggtga cggtcggcgg aatggccggt gccggtgccg gcgcgggtgg
    15061 cggagccttg tcgcggctgc gctcgatcac ttccaccttc ggttccttcc atggaccggt
    15121 caccttgtag gtacgggcgc caatctcgcc caatggtttg gacaataccg cattggtggc
    15181 cgcgcccagc gccgccccca ccgggccacc ggccaccgcc cccaccacgg tcagcagatt
    15241 gcctgcgcgc gggttgacgt cgatggtctg gtcgaactgc tggttgcgca ggtcggcctg
    15301 gccgcggatg gtgatgttgg ctgccgggcc ttcgatcagc accttgtctg tgcgcgccat
    15361 gccctggccg aactgcatgc tgccgtcgat ctggttgaac gcgaagccct tggagaagaa
    15421 gtcgcggaag tcgaacatca ggcgccgcgg cagctgggtc acgctgagca ggcccagcac
    15481 gcggccggcg cccggttcca gctccagcag ctggccgttg cgtgcgtgca ggtccaggcg
    15541 gccctgcagg ttgcccagct ggaagtccga cggcccccca ctccacgtgg cctgcagctg
    15601 cgcctggccg gaaccgccac gcagctggcc gccgtagtcg aggttctgca tcagtccgcc
    15661 caggtcctcg ctgcgcacct gcgcggtcag ttcggtgcgg gcaccaccgg tgcggcccag
    15721 ccagcgaccg ctgatgtcga tctcctggtc gggcgcacgg aagcgcagct catccacgtt
    15781 caggccattg gccagcggcc gcgtacgcag caccgcctgg cccagcacca ccttgccgaa
    15841 cttcaggtcg gcgatgtcca gcgcgaacgg cggcagcttg gccgggtcca tgtcgttggc
    15901 gcctgcctgt acccgtgccg gtgcggccgg tacacctgga gccgccggca atgactgcca
    15961 gtgcacgcgg tcgagctggc cactgatggt gccgccgtct gcattgggga cggtcaggcg
    16021 cccggccagc gacgggccgt ccaggcgtac atccagtgcc tgcgctcccg ggcgcagctg
    16081 caaccgggtc tgctcgaaca caccaccgat cagcatcagc ttgccgacct gcacgtccac
    16141 cgcacgcagc ggcatgccgt catcgtcgtt gccaccacgg gccaggccga tccactccag
    16201 cgcatccagg gtcgggctgc ggccattcac ggacagtccg ctcggtggcg gctcgcgatc
    16261 ggcatggtcg ctgcccagcg tcacctgcac acccgtctgg ttgttgtggc tgcgcgcagc
    16321 cagcgccagg cgctggccga acgacacgtc gatgcggccg gcccccatcg gcagctgtgc
    16381 agccacggtg gtcgccaacg gctcggcagc cggtttgtcc agcggcgccg gcaggtccag
    16441 ccgggtcccg accagatcgg agctcaaccg cagctcgctg ggcggcgcag gcgcccccgg
    16501 agcgaccttg ggcagattga ccgcgatggt ccacggcgag gtgccggcga tgtagggctt
    16561 cagccacgcc atttccggcg cgcggtcgat cagcacgcca gcatcgaggt tggccgacaa
    16621 ctgcgattca aaggccagct tgctgtcgtg cacgtagcca ccggcacgca ggctcagacg
    16681 accgtcctgg ccgaggtggc gcaccgccag ttcctcggcg ccgaaaccgc cgttgctgta
    16741 gcgcgcctgc ccgtgcatgt tgtcaaaggt gagctggaag cgcttgtcga ccagcttcac
    16801 gccggccaga tcgaccgttc cctgcaggtg gccgccacct tcatcgtggt gcagcggctg
    16861 cagcagatcg aaggtcacat gcgccgggcc cgcagcggtg aggttgtcca gggtgtcgcc
    16921 ataatccttg tgcagcgggc tctgccgcag catggccagc agcctgccgg cctcgctctg
    16981 cgcatcggca cgcacgtaca gcggctgctg cccgaaatcc tggatgcccg cctcgaattt
    17041 ctgcaccgcc acgccggcca gatcgccgcg accgtgcatg tcgaagccgg ggccgatgaa
    17101 ggcgatatcg gcatcgacct ggcgcatcaa cggccagtcg tgctggaagc ggatgtcacc
    17161 attggtgata tggccggtcg cctcgaagcg gccatcgttg ttgtcgaacg gccagtcgtc
    17221 caggtcgcca ctgaccaggc cgatgccgtt gcgcacctgc ccaccggcca gcgccatgtc
    17281 cagccagtcg gtggcgccct tgctcatctt ggagtggatc cagaagcgct tggccgcggt
    17341 catcggcacg tcgtccagct tggccgccag ctgcagccac ggccgcgtac cgtcgccctg
    17401 gaaccagaca ccaccgcgca cgtccgccgc ataatcggtg ccttccacgc gcatcgctgc
    17461 cgtgccgatg cgccagccac cgccttcatc gcgccagccc accacctggc ccgccaggtg
    17521 cagatcgtgg cgcacgccga agccggtcgg ccaatcgaac tgcagctggc gttgcgactg
    17581 cagctgcagg ctgaagccat ccgcgtcgcc ttcgaagcgc ccgcccaggc cgcgcaggcc
    17641 gggcgaattg cccacgctgg cgaagcccag cgactgcagt tcgccctgcg cccacagcgg
    17701 gccatcgcgt tcgcccgcca gctgcagctc gcgcacgtcc agctgcggcc tggacaggaa
    17761 cagccagcga cgcaggcccg gttcaagacg atcgctcagg gccagcgcac gcagcgcgat
    17821 gccggcctgc acttcgcgag aactgacccg catctgcttg ccgagctgca gctgcaggcc
    17881 atcgagctgc tgctcgcctt cttcggtttt caggcgcagg cgcggcacct gcaatgccca
    17941 gccatcggcc tggcgctgcc agcgcaggcg tgcctgcaac cgctgcagct gcagctgcgg
    18001 agccgccatc gcgggcatcg gtgcgccatc gatgcggaca tcacgcaggt ccgaatcggt
    18061 ggtcaccgcc accggcgcga aatcgcgcag ggtcagccac aggttgagtt cgcccttgcc
    18121 ttcgcgcagg cgcacaccgc cggccgccag cagcggcgac caggcatgaa aatcgaccgg
    18181 atcggcgccc agccaggcct ggccgttgcc gcgcacgcgg tccacgtcca gcaccgccgt
    18241 caacggcagc gcttcggtct gggcccaggc gcgcacgcct acacgcaggc ggtcgccatt
    18301 gacccgcagg cgcacgtcga tgcgtggcag cgtggtatcg atccccagcc ccggcgcatg
    18361 cacgcccagg cggcccccga tcacctgcag ttcgcccaga cggcgcagcg catccagcgg
    18421 gtccccgcca ttggcggcct gcggcaggcc acgcaccgac cagcggccgt cctcgccctg
    18481 ctgcaggtcc agtgccaggc cacgcaggcg cagttcggtc aacgagcggc cgggcagcag
    18541 cccgctgtac atcgatacca gcacctcggc ctcgctgatc gccaggccct ggccggcgcc
    18601 aatgcgcagg cccttgagct gcagcagcgg accacgccgg gtccaggccg tctgcaactg
    18661 gtcgaaacgc accggctggc cggcgcgttc actcaaccag gcggcaatcc tgtcgggatg
    18721 gcgctcggcc agcggcagca gctggctgag ggtgcccacc agcagtgcga gcccgaccag
    18781 gcccaccgcg caggcggcaa tgaaatgacg gcggatcctt cgcagtcgca ggcgcggcgg
    18841 cgcgctcatc ggccaccgcc ggcctgcggc cggcgaggat cagagcagaa caacatcgaa
    18901 ttgctcctgc aggtactgct cgtccgcctg gaagcggatg ctcttgccga ggaattcctc
    18961 cagctcggcc accgccgcgg attcctcgtc ggtgatgcgc gcgaccacct tggtcgaggc
    19021 gatcaccagc aggcgcgcgg catcgaactg gcgcacggca cgggtgatct cgcggaagat
    19081 ctcgtaggtc accgtttcgg tggtcttgat gctgccgcgg ccgctgcact gcgggcaggt
    19141 ttccgacagc tggcgctcca ggctttccac cgtgcgcttg cgggtcatct ccaccaggcc
    19201 cagcggcgag aagtcgtaca ccgtggtctt ggcatggtca cgggccagcg ccttttccag
    19261 cgtacgcaat acctggcggc ggtgctcggc atcatccatg tcgatgaagt cgatgatgat
    19321 gatgccgccc aggttgcgca ggcgcagctg ccgtgccacc gactgtgccg cttccaggtt
    19381 ggtgcggaac accgtctctt ccaggttgcg ctggccgagg aacgaaccgg tgttgacgtc
    19441 gatggtggtc atcgcctcgg tctggtcgat caccaggtaa ccaccggatt tcagcggcac
    19501 ctgcttgtcc agcgcgcggc cgatctcgtc ctccaccccg aacatgtcga agatcgggcg
    19561 atcgccgctg tacagctcga tcttctccgc cagcaccggc atgtacttgg caacaaaggc
    19621 ctgcaactgc gcgaaggtct ccttggagtc caccttcacc ttgtccacat ccttgcggat
    19681 caggtcgcgt accgatcgca gcggcaggct caggtcttca tagatgttgc tgcacgaggc
    19741 cgcttcgcgg ccacgacgct cgaccacgtt ccatacgcgc gacaggtagg cgatgtcctc
    19801 ggcgatggct tcggccggct ggccctcggc attggtacgc acgatgtagc cgtagccccc
    19861 gtgctgcgcc gacagttcgg tcaccagcgc cttcaggcgc gcacgctcgg tttcatcctc
    19921 gatgcgcgcc gacacgccca ccaccttgga ctgcggcagc agcaccatgt agcgcgaggg
    19981 aatgctgatc tgggtggtca ggcgggcgcc cttggtgccg atcggatcct tcaccacctg
    20041 caccacgatg tcctggccgt cgcgcagcag ctcgacgatc ggcacgctgg acggcggcgg
    20101 cagcgtggtg ttctcggtgt cggcactggc taccggcgcc ggccgcacca cgtcgttggc
    20161 gtgcaggaac gcggcacgct ccagcccgac ttcgacgaag gccgcctgca tgccgggcat
    20221 cacccgctgt accttgccct tgtagatgtt gccgaccaca ccccggcgcc agccgcgctc
    20281 gatgtgcagt tcctgcagca tgccattttc gatcaccgcg acccgggtct cgcgcggggt
    20341 cacattgacc aggatttcct cagacatcgg cagcctccct ggcggcatcg gcagtggggg
    20401 ccggcacgcc acagcgcgcc agcaaacgat cggtgtgcag caacggcagc cccatcaccc
    20461 cggagtaact cccggacagg tgctcgatcc agcgctcggc cccgccctgg atggcgtagg
    20521 cccccgcctt gtccagcggt tcgccggtgg ccacgtaggc ggcgatgtcg gcggcgtcga
    20581 tcggggcgaa ggtcacttcg gaaatgacca gctcgctgtc cagcccgtcc gcgccgacca
    20641 ccaccaccgc ggtcatcacc tgatgggtac gcccggcaag acgcgccagc atcgcccgcg
    20701 catcggcggc gtcggtgggc tttccgaaca cgtcgccgtc cagcaccacc tcggtgtccg
    20761 aaccgagcac ccgcgcctgc gggtcatcgg ccagcacccg ggccaggccg gcgcgcgcct
    20821 tgtcggcggc gacccggcag acatactgtt cggcgctttc agcgggcgcg cgctgctcg
//
