LOCUS       NZ_CP096975            22898 bp    DNA     circular CON 12-MAY-2024
DEFINITION  Stenotrophomonas sp. NY11291 chromosome, complete genome.
ACCESSION   NZ_CP096975
VERSION     NZ_CP096975.1
KEYWORDS    RefSeq.
SOURCE      Stenotrophomonas sp. NY11291
  ORGANISM  Stenotrophomonas sp. NY11291
            Bacteria; Pseudomonadota; Gammaproteobacteria; Lysobacterales;
            Lysobacteraceae; Stenotrophomonas.
REFERENCE   1  (bases 1 to 4961805)
  AUTHORS   Zhou,D.
  TITLE     Complete sequence of chromosome of strain NY11291
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 4961805)
  AUTHORS   Zhou,D.
  TITLE     Direct Submission
  JOURNAL   Submitted (02-MAY-2022) State Key Laboratory of Pathogen and
            Biosecurity, Beijing Institute of Microbiology and Epidemiology,
            No.20, Dongdajie, Fengtai, Beijing, Beijing 100071, China
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: HGAP v. v3.0
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 100.0x
            Sequencing Technology             :: PacBio RSII
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_023277365.1-RS_2024_05_12
            Annotation Date                   :: 05/12/2024 15:25:21
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 4,618
            CDSs (total)                      :: 4,528
            Genes (coding)                    :: 4,492
            CDSs (with protein)               :: 4,492
            Genes (RNA)                       :: 90
            rRNAs                             :: 5, 4, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 5, 4, 4 (5S, 16S, 23S)
            tRNAs                             :: 73
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 36
            CDSs (without protein)            :: 36
            Pseudo Genes (ambiguous residues) :: 0 of 36
            Pseudo Genes (frameshifted)       :: 11 of 36
            Pseudo Genes (incomplete)         :: 22 of 36
            Pseudo Genes (internal stop)      :: 6 of 36
            Pseudo Genes (multiple problems)  :: 2 of 36
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 04:39:31
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 1769225
            Orig. end                         :: 1792123
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP096975.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..22898
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="lanthipeptide-class-ii"
                     /region_number="3"
                     /rules="cds(LANC_like and DUF4135)"
                     /tool="antismash"
     cand_cluster    1..22898
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="cds(LANC_like and DUF4135)"
                     /kind="single"
                     /product="lanthipeptide-class-ii"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..22898
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:12898](+)"
                     /cutoff="20000"
                     /detection_rule="cds(LANC_like and DUF4135)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-ii"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..12898
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="cds(LANC_like and DUF4135)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-ii"
                     /protocluster_number="1"
     gene            71..586
                     /locus_tag="M1L61_RS08320"
                     /old_locus_tag="M1L61_08320"
     CDS             71..586
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014646745.1"
                     /locus_tag="M1L61_RS08320"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="M1L61_08320"
                     /product="hypothetical protein"
                     /protein_id="WP_010484296.1"
                     /transl_table=11
                     /translation="MRQSVSTVRVLSYALLAVAVAAGTTGCFKRGVKGDYALAPEMRPL
                     EVPPDLNLPTTTGDNKVPTLASATKPAAPAAAAPAVGNTGFTIAGGKDEAFAKVGTALE
                     GVEGVTIASRAQLLGSYDVAYEGSNFLVRVVAVDAGAYISAVDPRGLPATAEAPVKLIA
                     ALKAKLAQ"
     gene            complement(783..1106)
                     /gene="fdxA"
                     /locus_tag="M1L61_RS08325"
                     /old_locus_tag="M1L61_08325"
     CDS             complement(783..1106)
                     /GO_function="GO:0009055 - electron transfer activity
                     [Evidence IEA]"
                     /GO_function="GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA]"
                     /codon_start=1
                     /function="Ferredoxin"
                     /gene="fdxA"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005994928.1"
                     /locus_tag="M1L61_RS08325"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="M1L61_08325"
                     /product="ferredoxin FdxA"
                     /protein_id="WP_004153066.1"
                     /transl_table=11
                     /translation="MPFVVTENCIKCKHTDCVEVCPVDCFHEGPNFLVIDPDECIDCTL
                     CEPECPVNAIFPEDDVPAGQESFVALNAELAKEWPVLTVRKDPPADAGEWDGKPDKLKL
                     LER"
     gene            1299..2723
                     /locus_tag="M1L61_RS08330"
                     /old_locus_tag="M1L61_08330"
     CDS             1299..2723
                     /GO_function="GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1169: sugar
                     transport protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019661180.1"
                     /locus_tag="M1L61_RS08330"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="M1L61_08330"
                     /product="sugar porter family MFS transporter"
                     /protein_id="WP_053442820.1"
                     /transl_table=11
                     /translation="MSPAQPNIASHGGENTAFIVLISCVATLGGFLFGFDSGVINGTVD
                     GLRQAFNSSEAALGFEVASMLLGCAIGAFLAGWLGDRLGRRGVLIASALMFLVSALGAG
                     AAHASWLFIAARVLGGFAVGAASVMSPAYIAEVASARYRGRLATVQQMAIICGLFAAFL
                     SNYLLARAAGASTEPLWLGHEAWRWMFWMQALPSGLFLLLLLVIPESPRFLVVKGRQQQ
                     ARAVLSRLYGEAAAAAKQAEIEASLAQDQHKPRFADLRDTVSGKLRPILWVGIGLAMFQ
                     QLVGINVVFYYGAVLWQAVGFSESDALLINVLSGALSIGACLLTVLLIDRIGRKPLLWI
                     GSVGMSVALVLMVVAFASGSLADGRLQLSDGMGRLALVAANVYVVFFNMSWGPVMWVML
                     GEMFPNQIRGPALAVAGAAQWTSNFAITVTFPMLLAGIGLAGAYGIYTVAAILSIFFVV
                     RYVRETKGKELEQMEG"
     tRNA            complement(3172..3246)
                     /anticodon=(pos:complement(1772436..1772438),aa:Glu,
                     seq:ctc)
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /locus_tag="M1L61_RS08335"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /old_locus_tag="M1L61_08335"
                     /product="tRNA-Glu"
     gene            complement(3172..3246)
                     /locus_tag="M1L61_RS08335"
                     /old_locus_tag="M1L61_08335"
     misc_feature    3190..3205
                     /note="TFBS match to LexA_variant_1, Repressor of DNA
                     damage response, confidence: weak, score: 21.79"
                     /tool="antismash"
     gene            3299..4678
                     /gene="pcnB"
                     /locus_tag="M1L61_RS08340"
                     /old_locus_tag="M1L61_08340"
     CDS             3299..4678
                     /EC_number="2.7.7.19"
                     /GO_function="GO:0003723 - RNA binding [Evidence IEA]"
                     /GO_function="GO:1990817 - poly(A) RNA polymerase activity
                     [Evidence IEA]"
                     /GO_process="GO:0006378 - mRNA polyadenylation [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="pcnB"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005416117.1"
                     /locus_tag="M1L61_RS08340"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="M1L61_08340"
                     /product="polynucleotide adenylyltransferase PcnB"
                     /protein_id="WP_032128849.1"
                     /transl_table=11
                     /translation="MGNPETSTGSANIISSATSPFSLRVIPRDQHTISRKDISPNALRV
                     LYRLRDAGFGAYLVGGAVRDLLVNGQPKDFDVATDATPEQVKQLFRNCRLIGRRFRLAH
                     VVFGREIIEVATFRANSDDGSGDREMENGMLVRDNVYGTIEDDAIRRDFTCNALYYAIE
                     DFSVRDYTGGFEDVQARLMKLIGDPEQRYREDPVRMLRAVRLAAKLGFQIEEGTAAPIP
                     HLAGLLNEAAPARLFEEVLKLFLSGHGVASFEGLERYGLLDVLFPESAKALKSNRTGAL
                     RRMLVEGLANTDARVANDEPVSPAFLFALLLWPAFCRAQATLLKQGVAPEEAQRRAADR
                     VTVQQLSTIALPRRFSLPMQEIWLLQSRFSSRQRKRVFRTLTHPRFRAAFDFLSLRQVA
                     SAEHAADVEFWREAQAQSGRELESSLDVMHSEEGDDESGAPRKRRRRRRRPGAPAGAAG
                     E"
     gene            4682..5167
                     /gene="folK"
                     /locus_tag="M1L61_RS08345"
                     /old_locus_tag="M1L61_08345"
     CDS             4682..5167
                     /EC_number="2.7.6.3"
                     /GO_function="GO:0003848 -
                     2-amino-4-hydroxy-6-hydroxymethyldihydropteridine
                     diphosphokinase activity [Evidence IEA]"
                     /GO_process="GO:0009396 - folic acid-containing compound
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /gene="folK"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019338321.1"
                     /locus_tag="M1L61_RS08345"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="M1L61_08345"
                     /product="2-amino-4-hydroxy-6-
                     hydroxymethyldihydropteridine diphosphokinase"
                     /protein_id="WP_043402536.1"
                     /transl_table=11
                     /translation="MTLAWIGLGANLGDAAATVGAAIAALDALPGTRLRQASRLYATPA
                     WGNEDQPPFVNAVASVETTLPADELLQAMLALEQGFGRVRDPAMHWGPRALDLDLLLYG
                     AQVLDHPGLQVPHPYMHERAFVLVPLAEIAPDLAIPGHGRVQDAVMRVDACGIAPIG"
     gene            5202..6017
                     /gene="panB"
                     /locus_tag="M1L61_RS08350"
                     /old_locus_tag="M1L61_08350"
     CDS             5202..6017
                     /EC_number="2.1.2.11"
                     /GO_function="GO:0003864 - 3-methyl-2-oxobutanoate
                     hydroxymethyltransferase activity [Evidence IEA]"
                     /GO_process="GO:0015940 - pantothenate biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /function="Ketopantoate hydroxymethyltransferase"
                     /gene="panB"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005416119.1"
                     /locus_tag="M1L61_RS08350"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="M1L61_08350"
                     /product="3-methyl-2-oxobutanoate hydroxymethyltransferase"
                     /protein_id="WP_004153072.1"
                     /transl_table=11
                     /translation="MSTHADSKPWTVPALAEAKRNGQKLVMLTAYDAGFARTFDANGVD
                     LILIGDSLGMVVQGHDSTLPVTVADMVYHTRAVARVLQRALLVADLPFGADATPERALD
                     ASLQLLQAGAEMVKIEGAGFKVDIIRYLVEREIPVCAHLGLTPQSVLRLGGFKIQGRGD
                     AARQLVEDARAVAAAGASIMVLECVPTPVAAEVTAAVDVPTIGIGAGPQCDGQVLVLHD
                     FLGLDSGHRRPKFVKDFLAEGGSVAGATRAYADAVRDGSFPDEQHAYAQ"
     gene            6014..6853
                     /gene="panC"
                     /locus_tag="M1L61_RS08355"
                     /old_locus_tag="M1L61_08355"
     CDS             6014..6853
                     /EC_number="6.3.2.1"
                     /GO_function="GO:0004592 - pantoate-beta-alanine ligase
                     activity [Evidence IEA]"
                     /GO_process="GO:0015940 - pantothenate biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="panC"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011259031.1"
                     /locus_tag="M1L61_RS08355"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="M1L61_08355"
                     /product="pantoate--beta-alanine ligase"
                     /protein_id="WP_043402539.1"
                     /transl_table=11
                     /translation="MIQTFNELGALREQIAQWKREGLRVALVPTMGNLHGGHHSLVTLA
                     RQYADKVVTSIFVNPTQFGPNEDFSRYPRTPEADVAGLEQAGCDAVWLPSVEAMYPLGV
                     DKTTQMHAPGVSEVLEGASRPGHFDGVCTVVARLFLQVQPDVAVFGRKDYQQLAVIRQM
                     VAELSFPIQIVGAEIVRDEDGLAKSSRNQYLNAEQRPVATTIHRTLLGMREGYVAGHTR
                     VQIEADATAALQAAGFQVDYAVLRTPELAEPTFDGGGRVALIAARLGTTRLIDNLEF"
     misc_feature    6916..6927
                     /note="TFBS match to AfsR, Pleiotropic regulatory for
                     antibiotic production, confidence: medium, score: 18.76"
                     /tool="antismash"
     gene            6920..7417
                     /locus_tag="M1L61_RS08360"
                     /old_locus_tag="M1L61_08360"
     CDS             6920..7417
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010484309.1"
                     /locus_tag="M1L61_RS08360"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="M1L61_08360"
                     /product="hypothetical protein"
                     /protein_id="WP_248854563.1"
                     /transl_table=11
                     /translation="MKAPSTDTGRLAQASILAVLAAGMLPAQLFGGLLFALEFRRTPMP
                     ALTGGGLMFVLAVCNAIAVLLPMALILQSQQPLRRAGFVLVGFGLGALAMATCAWPGEN
                     QGPWLQRLRYVDTFDVISYALQVLAAGGFGLVAGLAFHTVFRLSLEGSSGHAAPPPPRE
                     GT"
     gene            7505..7885
                     /gene="panD"
                     /locus_tag="M1L61_RS08365"
                     /old_locus_tag="M1L61_08365"
     CDS             7505..7885
                     /EC_number="4.1.1.11"
                     /GO_function="GO:0004068 - aspartate 1-decarboxylase
                     activity [Evidence IEA]"
                     /GO_process="GO:0015940 - pantothenate biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="panD"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011036943.1"
                     /locus_tag="M1L61_RS08365"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="M1L61_08365"
                     /product="aspartate 1-decarboxylase"
                     /protein_id="WP_005409061.1"
                     /transl_table=11
                     /translation="MHLSLLKTKIHRATVTHSELNYEGSIAIDDNLLAATGIREFEQVH
                     IWDVTNGARFSTYAIRAEAGSGVVSLNGGAARHVQVGDIIIIAAFASMTEQEADSFKPK
                     LVYVDGKNQITHTNDTIPTQAA"
     gene            7882..9396
                     /gene="pgi"
                     /locus_tag="M1L61_RS08370"
                     /old_locus_tag="M1L61_08370"
     CDS             7882..9396
                     /EC_number="5.3.1.9"
                     /GO_function="GO:0004347 - glucose-6-phosphate isomerase
                     activity [Evidence IEA]"
                     /GO_process="GO:0006094 - gluconeogenesis [Evidence IEA]"
                     /GO_process="GO:0006096 - glycolytic process [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="pgi"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019300464.1"
                     /locus_tag="M1L61_RS08370"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="M1L61_08370"
                     /product="glucose-6-phosphate isomerase"
                     /protein_id="WP_248854564.1"
                     /transl_table=11
                     /translation="MTTNNGFDSLHSHAQRLKGASIPSLLAAEPGRVQDLALRVGPLYV
                     NFARQKYDAAALQALLALAAERDVGGAITRLFRGEQVNLTERRAALHTALRGDVVDAPV
                     AAEAYATARTIRQRMGVLVRALEDSGVTDVVSVGIGGSDLGPRLVADALRPVSGARLRV
                     HFVSNVDGAAMQRTLATLDPARTAGILISKTFGTQETLLNGQILHDWLGGSERLYAVSA
                     NPERAAKAFAIAADRVLPMWDWVGGRYSLWSAVGFPIALAIGFERFEQLLEGAAQMDAH
                     ALDAPLERNLPVLHGLTDIWNRNVLGHATHAVMTYDQRLALLPAYLQQLVMESLGKRVQ
                     RDGQPVTTDTVPVWWGGAGTDVQHSFFQALHQGTSIVPADFIGCVHNDDPYTINHQALL
                     ANLLAQTEALANGQSSDDPHRDYPGGRPSTLILLDALTPQALGALIAMYEHAVYVQSVI
                     WNINAFDQFGVELGKQLASGLLPALQGEDVAIADPMTREILAQLKG"
     CDS             9435..9551
                     /gene="allorf_1778660_1778776"
                     /locus_tag="allorf_1778660_1778776"
                     /protein_id="allorf_1778660_1778776"
                     /tool="antismash"
                     /transl_table=1
                     /translation="MSLRLPSIRSRMKAARPLIPSCFRAAHAALPRACRSAA"
     CDS_motif       9435..9479
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence: MSLRLPSIRSRMKAA"
                     /locus_tag="allorf_1778660_1778776_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       9480..9551
                     /prepeptide="core"
                     /locus_tag="allorf_1778660_1778776_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class II"
                     /score="-5.80"
                     /molecular_weight="2399.8"
                     /monoisotopic_mass="2398.3"
                     /core_sequence="RPLIPSCFRAAHAALPRACRSAA"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MSLRLPSIRSRMKAA"
                     /leader_location="[9434:9479](+)"
     misc_feature    complement(9542..9558)
                     /note="TFBS match to NtrC, Nitrogen regulatory protein C,
                     confidence: medium, score: 21.78"
                     /tool="antismash"
     misc_feature    9705..9723
                     /note="TFBS match to FuR_variant_2, Ferric Uptake
                     Regulator, confidence: medium, score: 27.95"
                     /tool="antismash"
     gene            9712..9918
                     /locus_tag="M1L61_RS08375"
                     /old_locus_tag="M1L61_08375"
     CDS             9712..9918
                     /codon_start=1
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268305.1"
                     /locus_tag="M1L61_RS08375"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="M1L61_08375"
                     /product="DUF6229 family protein"
                     /protein_id="WP_043402549.1"
                     /transl_table=11
                     /translation="MDLNDDVVSGWLNGADDVDGCANPAGSLFIYGAAATEAALTGASD
                     TMITGGTNECTTTVSVINHCLCC"
     CDS_motif       9712..9864
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence:
                     MDLNDDVVSGWLNGADDVDGCANPAGSLFIYGAAATEAALTGASDTMITGG"
                     /locus_tag="M1L61_RS08375_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       9865..9918
                     /prepeptide="core"
                     /locus_tag="M1L61_RS08375_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class II"
                     /score="-4.40"
                     /molecular_weight="1751.0"
                     /monoisotopic_mass="1749.8"
                     /core_sequence="TNECTTTVSVINHCLCC"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MDLNDDVVSGWLNGADDVDGCANPAGSLFIYGAAATEAALT
                     GASDTMITGG"
                     /leader_location="[9711:9864](+)"
                     /alternative_weights="1769.0"
     gene            10001..12898
                     /locus_tag="M1L61_RS08380"
                     /old_locus_tag="M1L61_08380"
     CDS             10001..12898
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-ii: DUF4135"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-ii: LANC_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1070: lanthionine synthetase C family protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019338325.1"
                     /locus_tag="M1L61_RS08380"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="M1L61_08380"
                     /product="type 2 lanthipeptide synthetase LanM family
                     protein"
                     /protein_id="WP_248854565.1"
                     /sec_met_domain="DUF4135 (E-value: 2e-77, bitscore: 258.9,
                     seeds: 79, tool: rule-based-clusters)"
                     /sec_met_domain="LANC_like (E-value: 4.6e-34, bitscore:
                     115.8, seeds: 47, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTASPAAAAFARITEHFLAHARAALATGLHDPAIALQPGERELLH
                     AQGDAALREHAQLKLNRVLLLELHAAARSGDIGPLGSAGALDEFVALATSEGFRTHLQR
                     RYPVLLPRLTRMLEGQCAAVVELAVRIGSDRAALAGLLGAPAGTLHAVALGRGDLHGGG
                     RTVARLQFEGGTVMYKPRSLRIDATLDGLLCTLFGDGPDRVCVPKVIDRGSHGWAAFAA
                     HRYCADDVELRAYYRGLGHWLAILRLVGGTDIHLENLIAVGPVPVVVDAESVFSRVIEI
                     EPSGLGDAYDTAVKLMRNSVLRTGIVPFRTAGLGMEGVDLSAAGALPGEQPRVQVPVIV
                     EGGTEPARLGMVEAEVSVAQNHPSAQPDVSLYWDHISEGFIDASGRLRALDAKGELMPL
                     LAAFEGCQVRDVRRPTMAYAELGRMLWHPASLHNEAQAVERAIDLLVRNAAVSPAAPSD
                     LDTVRGEVDDLRHGDIPIFTSQLDAARIRAIADNWRAMRIDLEDVTIRSTLVATDLNQH
                     ALARAEARSGYSYAAQHPRADDLDARRRTLAARAVESLLRLAVHGEDGSMTWITPEVTR
                     TGWTVQPVQPDLYFGLGGIAFALAAYHREVEQGRADPVAGLGPAIDGALAVFQTMCEQH
                     PAEIDGGFVGTGSQIWTLLALHDLLQRPALLVLAERCAEAAERRGFQEATKFELIDGVS
                     GMILPLLSLAAATGNARWLELAAAAGRRMQEAAIVDADGARWPTPQFREPIGGFGHGAM
                     GMGWALARLARSDAGSVPERAAWRQLAEGAFAFQAALFEPHTGHWRDIHLQDGQKNFPT
                     WCHGSVGIGLAAADLYARTGDPAQLRDMRRAVADARGKWGFSHTLCHGDVSTRELLVLA
                     AALDPEGCPYPQDEAAIEIVSSIEEHQGMVGGLTRAAFTPGLMIGLAGAIYGFLRMHPA
                     CALPSPLLQETTVARVDAPASRSITAQDRAVLAEV"
     gene            complement(12920..13483)
                     /locus_tag="M1L61_RS08385"
                     /old_locus_tag="M1L61_08385"
     CDS             complement(12920..13483)
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1008: response
                     regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005409063.1"
                     /locus_tag="M1L61_RS08385"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="M1L61_08385"
                     /product="response regulator transcription factor"
                     /protein_id="WP_005409063.1"
                     /transl_table=11
                     /translation="MSASTLGLLVDDDELYLRTLQRSLARKGLETQTAQDAASALALAR
                     QHPPAFALIDLKLGSDSGLALIQPLRALRADMRILLVTGYASIATAVEAIKLGADDYLP
                     KPATVPMILRALGEEDDGPADDGEMEVPDAMTPISRLQWEHIQQAMHETGGNVSAAARL
                     LGMHRRSLQRKLAKRPSPERDPSR"
     gene            complement(13480..14706)
                     /locus_tag="M1L61_RS08390"
                     /old_locus_tag="M1L61_08390"
     CDS             complement(13480..14706)
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1003: sensor
                     histidine kinase"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019661188.1"
                     /locus_tag="M1L61_RS08390"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="M1L61_08390"
                     /product="ATP-binding protein"
                     /protein_id="WP_049453348.1"
                     /transl_table=11
                     /translation="MTGPDAPFLRTLCSLRWLAVGGQAATILVATWVLGLPLPQLPLWA
                     GVAVLTLFNVYTQLRPEAADTAPLTAFGHILVDVIILTWMVGWSGGMANPFSSLFLILI
                     ALAAFALPLRWALAVALACLLGYAASGIFGQSLPDGYFRAQDLNRWGVVANFLISAAVV
                     LAFSTRLALALRQRELELSALRERFARNEGIVALATHAASVAHELNTPLATMTLLADDV
                     AERSEEPEVREDMETLRELLVQCRERVLALAAPASADGPGRAVSTAQQVLEQWRLVRPT
                     IDLHRNDDAPLRLPLDPGVGHLLMVLLNNAADAGEQAGRPRVDLDLRIEGNDLIGEVRD
                     YGHGFNARAAVLPGKLFGSSKSEGMGVGLALSHATIERLDGEMWMRPAQGAGSRVGFRL
                     PLALREETP"
     misc_feature    14776..14794
                     /note="TFBS match to FuR_variant_2, Ferric Uptake
                     Regulator, confidence: weak, score: 21.46"
                     /tool="antismash"
     gene            14821..16086
                     /gene="ispG"
                     /gene_synonym="gcpE"
                     /locus_tag="M1L61_RS08395"
                     /old_locus_tag="M1L61_08395"
     CDS             14821..16086
                     /EC_number="1.17.7.1"
                     /GO_function="GO:0046429 - 4-hydroxy-3-methylbut-2-en-1-yl
                     diphosphate synthase activity [Evidence IEA]"
                     /GO_process="GO:0044237 - cellular metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="ispG"
                     /gene_synonym="gcpE"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019300453.1"
                     /locus_tag="M1L61_RS08395"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="M1L61_08395"
                     /product="flavodoxin-dependent
                     (E)-4-hydroxy-3-methylbut-2-enyl-diphosphate synthase"
                     /protein_id="WP_049483053.1"
                     /transl_table=11
                     /translation="MHDAVTRPTPPSDATSWPRRQTHAVQIGGVTVGGGKPVVVQSMTN
                     TDTSDVASSVKQVAELWRAGSEMVRLTVNTVEAAAAIPRIVDKLAMMGIDVPLIGDFHY
                     NGHQLLTAEPACAEALAKYRINPGNVGFGKKKDLQFAQLIEFAIRYNKPVRIGANWGSL
                     DQALAAKLMDENNLREQPWDAGRVLREALIRSALDSAEQAVELGLPRDRIVLSAKVSGV
                     QELIAVYRDLAQRSDFALHLGLTEAGIGSKGIVASSAALSVLLQEGIGDTIRISLTPEP
                     GQSRTQEVIVAQELLQTTGQRAFTPLVTACPGCGRTTSEFFQELAKVVQNHVREKMPLW
                     KIHHPGAENMTLAVMGCIVNGPGESRHANIGISLPGTGETPAAPVFVDGEKKVTLRGDN
                     IAQEFVALIDDYVEHTYVRSAG"
     gene            16067..16816
                     /locus_tag="M1L61_RS08400"
                     /old_locus_tag="M1L61_08400"
     CDS             16067..16816
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014646755.1"
                     /locus_tag="M1L61_RS08400"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="M1L61_08400"
                     /product="phosphatase PAP2 family protein"
                     /protein_id="WP_019338327.1"
                     /transl_table=11
                     /translation="MSEAPDKPAILAAPESASGFRHWMARNAWRLVLLFGGVLLPLAGF
                     VALADEVHEFESFHFDAPLLWQMHGLHSPLLDRFFMLISKLGYEWFLIPADVLIIGALL
                     GYRRWREATFVAVSFVGSALLNMGSKHFFQRQRPSLWESIAPESTFSFPSGHAMGSMTL
                     AVTLVLLAWNTRWRWPVLLLAPAFSLLVSVSRVYLGVHYPSDILAGWCAALVWVVGCYL
                     VMFSRRHPWRRHGPPPAKASEASSQGD"
     CDS             16829..17017
                     /gene="allorf_1786054_1786242"
                     /locus_tag="allorf_1786054_1786242"
                     /protein_id="allorf_1786054_1786242"
                     /tool="antismash"
                     /transl_table=1
                     /translation="MRDVYVIDQLFRCSRFCKTGGKHNARYCDAQGRLPGSHSERACRG
                     IGTPPSLTCNGRIRRGT"
     CDS_motif       16829..16939
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence:
                     MRDVYVIDQLFRCSRFCKTGGKHNARYCDAQGRLPGS"
                     /locus_tag="allorf_1786054_1786242_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       16940..17017
                     /prepeptide="core"
                     /locus_tag="allorf_1786054_1786242_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class II"
                     /score="-6.30"
                     /molecular_weight="2605.9"
                     /monoisotopic_mass="2604.4"
                     /core_sequence="HSERACRGIGTPPSLTCNGRIRRGT"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MRDVYVIDQLFRCSRFCKTGGKHNARYCDAQGRLPGS"
                     /leader_location="[16828:16939](+)"
                     /alternative_weights="2624.0"
                     /alternative_weights="2642.0"
                     /alternative_weights="2660.0"
     gene            17018..17665
                     /locus_tag="M1L61_RS08405"
                     /old_locus_tag="M1L61_08405"
     CDS             17018..17665
                     /GO_process="GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /codon_start=1
                     /function="Response regulator containing a CheY-like
                     receiver domain and an HTH DNA-binding domain"
                     /gene_functions="regulatory (smcogs) SMCOG1016: LuxR family
                     DNA-binding response regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011408972.1"
                     /locus_tag="M1L61_RS08405"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="M1L61_08405"
                     /product="response regulator"
                     /protein_id="WP_004153112.1"
                     /transl_table=11
                     /translation="MTIRVYLVDDHALVRTGMKMILSGETDIEVVGEAETGEDALREVR
                     QLLPDVVLCDLHLPGVSGMEVTERIVRSHRNTRVVIVSVLEDGPLPKRLLEAGAAGYIG
                     KGCDAQELLRAVRDVAGGRRYLGTSIAQNLALSTVEGNGSPFDSLSPRELEVALLLTQG
                     LRQEDIARRLSLSAKTVNTHKARLFEKMGIHDNIALARMASQYGLVDPARPL"
     misc_feature    17040..17053
                     /note="TFBS match to ArgR, Regulator of arginine
                     biosynthesis genes, confidence: weak, score: 16.9"
                     /tool="antismash"
     gene            complement(17764..18423)
                     /gene="eda"
                     /locus_tag="M1L61_RS08410"
                     /old_locus_tag="M1L61_08410"
     CDS             complement(17764..18423)
                     /EC_number="4.1.2.14"
                     /EC_number="4.1.3.16"
                     /GO_function="GO:0008675 -
                     2-dehydro-3-deoxy-phosphogluconate aldolase activity
                     [Evidence IEA]"
                     /GO_function="GO:0008700 - 4-hydroxy-2-oxoglutarate
                     aldolase activity [Evidence IEA]"
                     /GO_process="GO:0009084 - glutamine family amino acid
                     biosynthetic process [Evidence IEA]"
                     /GO_process="GO:0009255 - Entner-Doudoroff pathway through
                     6-phosphogluconate [Evidence IEA]"
                     /codon_start=1
                     /gene="eda"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008265926.1"
                     /locus_tag="M1L61_RS08410"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="M1L61_08410"
                     /product="bifunctional 4-hydroxy-2-oxoglutarate
                     aldolase/2-dehydro-3-deoxy-phosphogluconate aldolase"
                     /protein_id="WP_054171470.1"
                     /transl_table=11
                     /translation="MGIEQHQVKAAELLHAAGILPVVTIHTLDQARAVSAALLEGGLPA
                     IELTLRTPVAMEALAMLKRELPDVVVGAGTVLTVEQMQQSIDAGADFLVTPGTPPTLAD
                     ALAAAPLPVVPGAATPTELLSLYARGFRVCKLFPATAVGGLAMIKGLAGPVADLKLCPT
                     GGITENTAAEYLEQKNVVCIGGSWMVPGNWIAGGEWDKVRASAADAAKIIQRVRGH"
     misc_feature    complement(18391..18400)
                     /note="TFBS match to AbrC3, Antibiotic production
                     activator, confidence: strong, score: 18.07"
                     /tool="antismash"
     misc_feature    complement(18621..18636)
                     /note="TFBS match to ClgR, Caseinolytic protease gene
                     regulator, confidence: weak, score: 22.9"
                     /tool="antismash"
     gene            complement(18629..20545)
                     /gene="edd"
                     /locus_tag="M1L61_RS08415"
                     /old_locus_tag="M1L61_08415"
     CDS             complement(18629..20545)
                     /EC_number="4.2.1.12"
                     /GO_function="GO:0004456 - phosphogluconate dehydratase
                     activity [Evidence IEA]"
                     /GO_process="GO:0009255 - Entner-Doudoroff pathway through
                     6-phosphogluconate [Evidence IEA]"
                     /codon_start=1
                     /gene="edd"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015472018.1"
                     /locus_tag="M1L61_RS08415"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="M1L61_08415"
                     /product="phosphogluconate dehydratase"
                     /protein_id="WP_248854566.1"
                     /transl_table=11
                     /translation="MSLHPQLQAITERVIRRSAASRAAYLAAIDASLREGPFRSRLSCG
                     NLAHGFAACGGTDKSRLRGGVTPNLGIITAYNDMLSAHQPFETYPEQIREIARELGATA
                     QVAGGVPAMCDGVTQGRGGMELSLFSRDVIAQATAIGLSHDMFDTTVYLGVCDKIVPGL
                     LIGALAFGHLPAVFVPAGPMTPGIPNKQKAEVRERYAAGEATREELLEAESASYHGAGT
                     CTFYGTANSNQVLLEAMGVQLPGASFVNPGTPLRDALTREATERALDITALGDDFRPLG
                     RIIDERAIINAVIALMATGGSTNHTIHWIGVARAAGIVLTWDDFDELSQLIPLLARVYP
                     NGDADVNRFAAAGGPAFVFGELIKAGLMHGDLVSVARGGMADYAREPQLRDGQLVYLPG
                     LERSADDEVVRGVDNPFEHQGGLRLLRGNLGKSLIKLSAVKPQYRTIEAPAVVVDAPQV
                     LNKLHAGGLLPQDFVAVVRYQGPRANGMPELHSLAPLLGLLQNQGRRVALVTDGRLSGA
                     SGKIPAAIHVTPEAARGGPLAKVREGDMIRLDGEAGTLEVLVDAAEWAARPLAPNTAPA
                     AHDLGRNLFAINRRVVGPADQGAISISCGPAAADGGPWDYDAEYELGHDAAAAAAPHEA
                     KDA"
     misc_feature    20504..20517
                     /note="TFBS match to BldD, Development and antibiotic
                     global regulator, confidence: weak, score: 18.77"
                     /tool="antismash"
     gene            complement(20604..21326)
                     /gene="pgl"
                     /locus_tag="M1L61_RS08420"
                     /old_locus_tag="M1L61_08420"
     CDS             complement(20604..21326)
                     /EC_number="3.1.1.31"
                     /GO_function="GO:0017057 - 6-phosphogluconolactonase
                     activity [Evidence IEA]"
                     /GO_process="GO:0006098 - pentose-phosphate shunt [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="pgl"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012479767.1"
                     /locus_tag="M1L61_RS08420"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="M1L61_08420"
                     /product="6-phosphogluconolactonase"
                     /protein_id="WP_248854567.1"
                     /transl_table=11
                     /translation="MSPSFHDDRIEFIPHGDADGWIEAVAAEMAQTLNHDINEVGRARI
                     LLSGGTTPAPVYQALAELDVHWDRVEVSLADERWLSPQDRDSNAWLVREHLLKRAEGAH
                     FDPLVRIGKPLPECVYTANLQAQHSQPPSLVALGMGNDGHTASLFPGSKDLARALESTL
                     PYAALDATGCPGANQWPLRITLTPHGLDQCRQRLLLLRGKQKLQVLRQALDSNDAQQYP
                     ILNAINLDGARLRVHWAD"
     gene            complement(21323..22330)
                     /gene="glk"
                     /locus_tag="M1L61_RS08425"
                     /old_locus_tag="M1L61_08425"
     CDS             complement(21323..22330)
                     /EC_number="2.7.1.2"
                     /GO_function="GO:0004340 - glucokinase activity [Evidence
                     IEA]"
                     /GO_process="GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="glk"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005416128.1"
                     /locus_tag="M1L61_RS08425"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="M1L61_08425"
                     /product="glucokinase"
                     /protein_id="WP_010484331.1"
                     /transl_table=11
                     /translation="MSASSQPVLVADIGGTNARFALADTSQDAPLQKDSIREYAVAEFP
                     SLGDAARHHLEQIGATASRGVFAVAGRVDGDEARITNHPWVISRSRTAAMLGFDELHLI
                     NDFAAQAMAISLLQPDDVVQVGGAAWVPGKPGQPRNYAVIGPGTGLGVGGLILRHGRCY
                     PLETEGGHVSFPPGTPEEIRILEILSEQFGRVSNERLICGPGLVNIHRAVCEMAGIDPG
                     QLQPVDVTARALHGDPQAMRTVDVFCAVFGAIAGDLVLTQGAWDGVFLTGGLTPKMLDS
                     LQHSGFRQRFEHKGRFSSIMARVPSLAVMHPHAGLLGAAAYAADAERDAPGVAA"
ORIGIN
        1 gcgacatcgc cgccctcgaa gccctttcca gccactgacc ttccgtcttg gtctgaccca
       61 ggagattcac atgcgtcaat ccgtatccac cgtccgcgtg ctgtcctacg ccctgcttgc
      121 ggtggccgtt gccgccggca ccaccggctg cttcaagcgt ggtgtcaagg gcgactacgc
      181 cctggccccg gaaatgcgtc cgctggaagt gccgccggac ctgaacctgc cgaccaccac
      241 cggtgacaac aaggtgccga cgctggcatc ggcgaccaag ccggccgcgc ctgcggctgc
      301 ggccccggcc gtgggcaaca ccggtttcac catcgccggt ggcaaggacg aggctttcgc
      361 caaggtcggc accgcgctgg aaggcgtgga aggtgtgacc attgccagcc gcgcgcagct
      421 gctgggctcg tatgacgtgg cctacgaagg cagcaacttc ctggtccgcg tggtcgccgt
      481 cgatgctggc gcctacatct ccgcggtcga cccgcgtggc ctgccggcca ccgccgaagc
      541 gccggtgaag ctgatcgctg cgctgaaggc gaagctggcg cagtaagggc tggtcgggtg
      601 ggggcgggcc ttggtccgca cccgctctgg tggaggccga ccttggtcgg cgcttctgtg
      661 ccaaccaagg ttggcacctg ccggatcgca aggttggcat accggatctt gcggttggcg
      721 tttaccggaa aacagaaaag ggcgcccgtg ggcgcccttt tcgttgccgc cgtgggcgct
      781 tctcagcgct ccagcagctt cagcttgtcc ggcttgccgt cccattcgcc ggcatcggcg
      841 ggcgggtcct tgcgcacggt cagcaccggc cactccttcg ccagctcggc gttgagggcc
      901 acgaaacttt cctggccggc aggaacatcg tcctccggga agatcgcgtt gaccgggcat
      961 tccggttcgc agagggtgca gtcgatgcac tcatccgggt cgatcaccag gaagttgggg
     1021 ccttcgtgga agcaatccac ggggcacact tccacgcaat cggtgtgttt gcacttgatg
     1081 cagttttcgg tgacgacaaa gggcatgggc tgggggtgga tcgattcctg aaccccccaa
     1141 ttctagaaca ggttggcccc cggtgtcggt gcggggcgga aatcgggcgt ctggcaggcg
     1201 cggccgtggc ggtcattggc ggcagggcga ggcctgtgcg acgctgcggg tcagccggct
     1261 gcgtcggatg gccggacccc ttcccagcag gatcgtccat gtccccagcc cagcccaaca
     1321 tcgcctccca tggcggtgag aacactgcat tcatcgtcct gatcagctgc gtggccaccc
     1381 tgggtggatt cctgttcggc ttcgacagtg gtgtcatcaa tggcacggtc gatggcctgc
     1441 gccaggcttt caactccagt gaggcggcgc tcggtttcga ggtcgcctcg atgctgctgg
     1501 gctgcgcgat cggtgccttc ctggccggct ggctgggaga tcgcctgggc cgtcgtggcg
     1561 tgctgatcgc ctcggcgctg atgttcctgg tttcggcgct gggtgccggt gccgcacacg
     1621 cctcctggtt gttcattgcc gcacgcgtgc tcggcggctt cgcggtgggc gcggccagtg
     1681 taatgtcgcc ggcctacatt gccgaggtgg cttcggcgcg ctatcgcggg cgtttggcca
     1741 cggtgcagca gatggcgatc atctgcggcc tgttcgccgc cttcctcagc aattacctgc
     1801 tggcccgtgc cgctggggcg tcgaccgagc cgctatggct gggccatgag gcctggcgct
     1861 ggatgttctg gatgcaggcg ctgccgtcgg ggctgttcct gctgttgttg ctggtgattc
     1921 cggaaagccc gcgctttctg gtcgtgaaag ggcgtcagca gcaggcgagg gcggtactgt
     1981 cgcggctgta cggcgaggcc gctgcggcgg ccaagcaggc cgagatcgaa gccagcctgg
     2041 cgcaggacca gcacaagccg cgctttgccg acctgcgcga cacggtcagc ggcaagctgc
     2101 gcccgatcct ctgggtgggc atcggcctgg ccatgttcca gcagctggtc ggcatcaacg
     2161 tggtgttcta ttacggcgcg gtgctgtggc aggcggtggg cttctcggaa agcgatgcgc
     2221 tgctgatcaa cgtgctgtcc ggcgcgctga gcatcggcgc ctgtctgctg acggtgctgt
     2281 tgatcgaccg catcgggcgc aagccgctgc tgtggatcgg ttcggtcggc atgtcggtgg
     2341 cgctggtgct gatggtggtt gccttcgcca gtggcagcct ggccgacggt cgcctgcagt
     2401 tgtccgacgg catgggccga ctggcgctgg tggcagccaa cgtctacgtg gtgttcttca
     2461 acatgtcctg gggcccggtg atgtgggtga tgctgggcga gatgttcccc aatcagatcc
     2521 gtggtccggc gctggcggtg gccggcgccg cgcaatggac ctcgaacttc gcgatcaccg
     2581 tgaccttccc gatgctgctg gccggcatcg gcctggccgg cgcctacggc atctatacgg
     2641 tggcggccat cctctcgatc ttcttcgtgg tccgctacgt gcgcgagacc aagggcaagg
     2701 agctggagca gatggaaggc tgacggcgac tggcttcggt tgcattccgt tggcgcctgc
     2761 ctgtccagag tgtgaggggg caggccgccc tctccaggac acgcaaaagc ccatccatgg
     2821 tgctcgatgg cgccatccat ggcgccaacg gtcctggaga gggcggcccg ccccctcctg
     2881 acagtttcat ggtgcgtgcg gatgcggcga agtgctggtc ggttattgcc gcagctcgcg
     2941 ggaaaccgtc cagagtcggt ggggtcaccc agggcaggac cgttgcgcca aggatggcgc
     3001 catcgagccc ccatggatgg gttcacggcg tgtcctgccc tgggtgaccc caccggctca
     3061 agccgattgc aggcaggcgc caaagcgacc aagccgatcg atgccattgc aaaccccgga
     3121 aaacagaaaa gcccacacaa ggcgggcttt ttcggttcct gctgcggcga ctggcgctcc
     3181 ctaggggact cgaacccctg ttttagcctt gagagggcca cgtcctaacc actagacgaa
     3241 gggagcgtaa ctgtgtcgct gccgaggcag gagcgctagt atatgcacct cgatgccatt
     3301 gggcaatccc gaaacttcaa ccggaagcgc caacatcatt tcctctgcta catcaccgtt
     3361 cagcctgcgc gtcatcccgc gcgaccagca cacgatctcc cgcaaggaca tcagcccgaa
     3421 cgccctgcgc gtgctttatc gcctgcgcga tgccggcttc ggcgcctacc ttgtcggcgg
     3481 cgcggtgcgc gatctgctgg tcaatggcca acccaaggat ttcgacgtgg ccaccgatgc
     3541 cacgcccgaa caggtcaagc agctgttccg caactgccgc ctgatcggtc gtcggttccg
     3601 cctcgcccac gtcgtgttcg gccgcgagat catcgaagtc gccaccttcc gtgccaacag
     3661 cgatgacggc agcggcgacc gcgagatgga aaacggcatg ctcgtgcgcg acaacgtgta
     3721 cggcaccatc gaagacgacg ccatccgccg cgacttcacc tgcaacgccc tgtactacgc
     3781 catcgaggac ttctcggtgc gtgattacac cggcggcttc gaagacgtcc aggcgcgcct
     3841 gatgaaactg atcggcgacc ccgagcagcg ttatcgcgaa gacccggtgc gcatgctgcg
     3901 tgcggtgcgc ctggcggcca agctcggctt ccagatcgaa gagggcaccg ccgcgccgat
     3961 cccgcacctg gctggcctgc tcaacgaagc cgcaccggca cgcctgttcg aggaggtgct
     4021 caagctgttc ctgtccgggc acggcgtggc cagcttcgaa ggccttgagc gttacggcct
     4081 gctcgacgtg ctgttcccgg aaagcgccaa ggcattgaag tccaaccgca ccggtgcgct
     4141 gcgccgcatg ctggtcgagg gcctggccaa caccgatgcg cgcgtggcca acgacgagcc
     4201 ggtctcgccg gcgttcctgt tcgcgctgct gctgtggccg gcgttctgcc gcgcgcaggc
     4261 gaccctgctc aagcagggcg tggcaccgga ggaggcacag cgccgtgctg ccgaccgtgt
     4321 gaccgtgcag cagctgagca ccatcgcatt gccgcgccgc ttttcgctgc cgatgcagga
     4381 aatctggctg ctgcagtcgc gcttcagttc gcgccagcgc aagcgcgtgt tccgtaccct
     4441 gacccacccg cgcttccgcg ccgcgttcga cttcctcagc ctgcgtcagg tggcctcggc
     4501 cgagcacgcc gccgatgtcg agttctggcg cgaggcacag gcgcagtccg gccgcgagct
     4561 ggaatcgtcg ctggacgtga tgcacagcga agagggtgat gacgagagcg gggcaccgcg
     4621 caagcgccgc cgtcgccgcc gtcgtccggg cgccccggcc ggtgcggctg gcgagtaaac
     4681 gatgactctt gcctggatcg gcctcggcgc caaccttggc gacgcggccg cgaccgtggg
     4741 cgcggcgatt gccgcgctcg acgcgctgcc cggtacccgc ctgcgccagg cctcgcggct
     4801 ttatgccacg ccggcctggg gcaatgaaga ccagccgccg ttcgtcaacg cggtggcctc
     4861 ggtcgaaacc acattgccgg ccgatgagct gctgcaggcg atgcttgcgc tggagcaggg
     4921 ttttggccgc gtgcgcgacc ccgcgatgca ctggggcccg cgcgcgctgg acctggacct
     4981 gctgctgtat ggcgcgcagg tgctcgacca tcccggcctg caggtaccgc atccctacat
     5041 gcacgagcgt gccttcgtgc tggtgccgct ggccgaaatc gcgccggatc tggccattcc
     5101 cggccatggc cgcgtgcagg atgcagtgat gcgggtggat gcctgcggga tcgcgccgat
     5161 agggtgataa tgcccgggtt atctcccccg gttatcagca catgagcacc cacgcagaca
     5221 gcaagccctg gaccgttccc gccctggccg aggccaagcg caatggccag aagctggtca
     5281 tgttgaccgc ctacgacgcc ggctttgccc gtaccttcga tgccaatggc gtcgacctga
     5341 tcctgatcgg cgattcgctg ggcatggtcg tgcagggcca tgattcgacc ctgccggtga
     5401 ccgtggccga catggtctac cacacccgcg ccgtagcccg cgtgctgcag cgtgcgctgc
     5461 tggtggccga cctgccgttc ggtgccgatg ccaccccgga acgcgcgctg gatgcatcgc
     5521 tgcagctgct gcaggccggt gccgagatgg tcaagatcga aggtgccggc ttcaaggtcg
     5581 acatcatccg ttacctggtc gagcgtgaga ttccggtctg cgctcacctg ggcctgaccc
     5641 cgcagtcggt gctgcgcctg ggcggcttca agatccaggg ccgtggcgat gccgcgcgcc
     5701 agctggtgga agatgccagg gccgtggccg ctgccggcgc cagcatcatg gtgctcgaat
     5761 gcgtgccgac cccggtcgcc gccgaagtga ccgcggcggt ggatgttccg accatcggca
     5821 tcggtgccgg cccgcagtgc gacggccagg tgctggtgct gcacgatttc ctcggcctgg
     5881 acagtggcca tcgccgtccc aagttcgtca aggatttcct tgccgaaggc ggttcggtgg
     5941 ccggtgccac ccgcgcctat gccgacgccg tgcgcgacgg cagcttcccc gacgaacagc
     6001 acgcctacgc ccaatgatcc agaccttcaa cgagctcggc gcgctgcgcg agcagatcgc
     6061 ccagtggaag cgcgagggcc tgcgcgtggc gctggtgccg accatgggca acctgcatgg
     6121 tggccaccat tcgctggtga ccctggcccg ccagtacgcc gacaaggtgg tgacgagtat
     6181 cttcgtcaac ccgacccagt tcgggccgaa cgaggacttc agccgctacc cgcgcacgcc
     6241 cgaggctgac gtggccgggc tggagcaggc cggctgcgat gcggtgtggc tgcccagcgt
     6301 cgaggcgatg tatccgctgg gcgtggacaa gaccacgcag atgcacgcgc cgggtgtcag
     6361 tgaagtgctg gaaggcgcca gccgcccggg ccacttcgac ggcgtgtgca cggtggtggc
     6421 gcgcctgttc ctgcaggtgc agccggatgt ggccgtgttc ggccgcaagg attaccagca
     6481 gctggccgtg atcaggcaga tggtggccga gctgtcgttc ccgatccaga tcgtcggtgc
     6541 cgagatcgtg cgcgacgagg atggcctggc caagagttcg cgcaaccagt acctcaacgc
     6601 cgaacagcga ccggttgcga cgaccattca ccgcacgctg ctgggcatgc gcgaaggcta
     6661 cgtggccggg cacacgcggg tgcagatcga ggccgacgcc acggcggcgc tgcaggcggc
     6721 cggtttccag gtcgactacg ccgtgctgcg cacgcccgag ctggccgagc cgaccttcga
     6781 cggcggtggc cgcgtggcgc tgatcgccgc gcgcctgggc acgacgcgcc tgattgacaa
     6841 cctggagttc tgagccgcac gcggcttggg ggcgcccgca acgggcgcct ctgcacttcc
     6901 cacggacggg agaccggaaa tgaaagcccc cagcactgat accggccgcc tcgcccaggc
     6961 ctcgatcctg gcggtgctgg cggcaggcat gttgccggcc cagctgtttg gcggcctgtt
     7021 gttcgcgctc gaattcaggc gtacgccgat gcctgcgctc accggtggtg ggctgatgtt
     7081 cgtactggcc gtctgcaatg ccatcgcggt gttgctgccg atggcgctga tcctgcagtc
     7141 tcagcagccc ctgcgccggg ccggcttcgt gctggtcggc ttcgggctgg gcgcgctggc
     7201 catggccacc tgcgcctggc cgggagaaaa ccaggggccc tggctgcagc gcctgcgcta
     7261 cgtcgatacc ttcgatgtga tcagctatgc cttgcaggtg ctggccgcgg gaggcttcgg
     7321 gctggtcgcc gggctggcct tccatacggt gttccggctg tctctggaag gcagttccgg
     7381 gcacgcagcg ccgccgccgc cgcgggaggg cacctgaaca gccttcagcg tcctgctgca
     7441 gccccctgac gatggtcaag cgggtgctag aatccgctct ttcctttgcc gttgcagcgc
     7501 ccccatgcac ctgtccctgc tcaagaccaa gatccaccgc gccaccgtca cccattccga
     7561 gctgaactac gaaggctcga tcgccatcga tgacaacctg ctggctgcca ccggcatccg
     7621 cgagttcgaa caggtgcaca tctgggacgt gaccaacggt gcgcgcttct cgacctatgc
     7681 catccgcgcc gaagccggca gcggcgttgt ctcgctcaac ggtggcgccg cgcgccacgt
     7741 gcaggtcggt gacatcatca tcatcgccgc gttcgccagc atgaccgagc aggaagctga
     7801 cagcttcaag ccgaagctgg tgtacgttga tggcaagaac cagatcaccc acaccaacga
     7861 cacgatcccg acccaggccg catgacaacg aacaacggat tcgactcgct gcattcccat
     7921 gcccagcgcc tgaagggcgc aagcatcccc agcctgctcg ccgccgaacc cggccgcgtg
     7981 caggatctgg cgctgcgggt cggtccgttg tacgtcaact tcgcccggca gaaatacgat
     8041 gccgcggcgc tacaggcatt gctggctttg gccgccgagc gtgatgtcgg cggtgccatc
     8101 acccgcctgt tccgtggcga gcaggtcaat ctgaccgaac gtcgcgccgc gctgcacacc
     8161 gcgctgcgtg gcgatgtggt cgatgcgccg gtggcagccg aggcctatgc caccgcgcgc
     8221 acgatccgcc agcgcatggg cgtgctggtg cgcgcgctgg aagacagcgg cgtcaccgac
     8281 gtggtcagcg tcggcatcgg cggttccgat ctcggtccgc gcctggtcgc cgatgcgctg
     8341 cgcccggtca gcggcgcgcg cctgcgcgtg catttcgtgt cgaacgtgga cggcgccgcc
     8401 atgcagcgca cgctggccac gctggatccg gccaggaccg ccggcatcct catttccaag
     8461 accttcggta cccaggaaac cctgctcaac gggcagatcc tgcacgactg gctggggggc
     8521 agcgagcgcc tgtacgcggt cagcgccaac cccgagcgtg cggccaaggc cttcgccatc
     8581 gccgccgatc gcgtgctgcc gatgtgggat tgggtcggtg gccgttattc gctgtggtcg
     8641 gccgtcggtt tcccgattgc actggccatc ggtttcgagc gtttcgaaca actgctggaa
     8701 ggtgccgcgc agatggacgc gcatgcactg gatgcgccgc tggagcgcaa cctgccggtg
     8761 ctgcacggcc tgaccgacat ctggaaccgc aacgtgctgg gccatgccac gcacgcggtg
     8821 atgacctacg accagcgcct ggcgttgctg ccggcctacc tgcagcagct ggtgatggaa
     8881 agcctgggca agcgcgtgca gcgtgatggg cagccggtca ccaccgacac cgtgccggtg
     8941 tggtggggcg gggcgggcac cgacgtgcag cacagtttct tccaggcgct gcaccagggc
     9001 accagcatcg tgccggccga tttcatcggc tgcgtgcaca acgatgatcc ctacacgatc
     9061 aatcatcagg cgctgctggc caacctgctg gcacagaccg aggcgctggc caacggccag
     9121 agcagcgacg acccgcaccg cgattatccg ggcggccgcc cgagcacgct gatcctgctc
     9181 gacgcgctga ccccgcaggc gctgggcgca ctgatcgcca tgtacgaaca cgctgtgtac
     9241 gtgcagtcgg tgatctggaa catcaatgcc ttcgaccagt tcggtgtcga gcttggcaag
     9301 cagctggcca gtggcctgtt gccggcgctg cagggtgagg atgtggcgat tgccgatccg
     9361 atgacccgcg agatcctggc gcagctgaag ggctgatacg gggtgcggat gggccggcgc
     9421 cagccggcca tcccatgtct ctccggttgc cttcgatccg gtcgcgcatg aaggctgcgc
     9481 ggccactcat tccgtcctgt ttccgtgctg cacatgccgc gcttccgcgt gcctgccgca
     9541 gcgcagcttg actgtgcatt gcgtgccaat gcagtgtgca cgggcggctg tacctgtcat
     9601 ccagtatcgc tcgcagcatg atgttgatgc cagggactgg ccgtatccga aggaacgtgg
     9661 aatcgatcca cgttctcaac gcctcatgtt gtgaatgaca ggagattgcg aatggatctg
     9721 aatgacgatg ttgtgtccgg ctggctcaac ggcgcggacg atgtggatgg gtgcgccaac
     9781 cctgcgggtt cgctgttcat ctacggtgcg gcagccaccg aagcggccct caccggagct
     9841 tcggacacca tgatcaccgg gggcaccaac gagtgcacca ccacggtatc ggtgatcaac
     9901 cactgcctgt gttgctgatg taacccgagc cggcacgcag aggcatgcag ctgcgtgccg
     9961 gcgactggaa cagacttccc gataccttgc agggggcgta atgaccgctt ctccggctgc
    10021 ggctgcgttt gcgcgcatca ccgaacattt ccttgcccat gcgcgcgccg cgttggcgac
    10081 tggcctgcat gaccctgcca ttgcgctgca gcccggtgag cgtgaactgc tgcacgcgca
    10141 gggcgacgcg gcgctgcgtg agcatgccca gctcaagctc aaccgcgtgc tgctgctgga
    10201 actgcacgcc gctgcacgca gtggtgacat cggcccgctg ggcagtgcgg gtgcgctgga
    10261 cgaattcgtt gccctggcca cgagcgaggg cttccgtacg catctgcagc gacgctatcc
    10321 ggtgctgctg ccgcgcctga cgcgcatgct cgaaggacaa tgtgcggcgg tggtggagct
    10381 cgctgtgcgc atcggcagtg atcgtgcggc gctggcgggg ttgctgggcg cgccggcggg
    10441 cacgctgcat gccgttgcat tgggacgggg tgacctgcat ggtggcggcc ggactgtggc
    10501 acggctgcag ttcgaaggcg gcacggtgat gtacaagcca cgctcattgc gcatcgatgc
    10561 gacgctcgac ggcctgttgt gcacgctctt cggtgacggc cctgaccgcg tatgcgtgcc
    10621 gaaggtgatt gatcgtggca gccacggctg ggccgccttc gccgcgcacc gctactgtgc
    10681 cgatgacgtt gaactgcgtg cctactatcg cggtcttggc cattggctgg cgatcctgcg
    10741 cctggtgggt ggcaccgaca tccatctgga gaacctgatc gcggtcgggc cggtgccggt
    10801 tgtggtcgac gccgaaagcg tgttctcccg ggtaatcgaa atcgagccat caggacttgg
    10861 cgatgcgtac gacaccgccg tcaagctgat gcgcaattca gtgctgcgta ccggaatcgt
    10921 gccgttccgt actgccggcc tgggcatgga aggcgtggat ctgtctgcag ccggcgcact
    10981 gccgggcgag cagccgcggg tgcaggtgcc ggtgattgtc gagggcggga cggaaccggc
    11041 ccggttgggc atggtcgagg ccgaggtctc cgttgcgcag aatcatccca gcgcgcagcc
    11101 cgatgtgtcg ttgtactggg accacatcag cgagggcttc atcgacgcca gtgggcgcct
    11161 gcgcgcgctc gatgccaagg gcgaactgat gccactcctg gcggctttcg aaggctgtca
    11221 ggtgcgcgac gtgcggcggc cgacaatggc ctacgcagag ctcgggcgga tgctctggca
    11281 tccagcctcg ctgcacaacg aagcccaggc ggttgaacgc gcgatcgatc tgctggtgcg
    11341 caatgcggcg gtgtcgccgg ctgcgccatc ggacctggac accgtccgcg gcgaagtgga
    11401 tgacctgcgc cacggcgata ttccgatttt cacctcgcag ctggatgcgg cccgtatccg
    11461 cgccatcgcc gacaactggc gcgcgatgcg catcgacctg gaagacgtga ccatccgcag
    11521 cacgctggtg gccaccgacc tgaaccagca tgcgctggcc cgcgccgagg ctcgatccgg
    11581 ctacagctat gccgcacagc atccgcgtgc ggacgacctg gacgcgcgcc gtcgtacgct
    11641 ggccgcgcgc gcggtggaga gcctgctgcg gctggcggtg catggtgagg acggttcgat
    11701 gacctggatc acccccgagg tgacccgtac cggatggacc gtccagccgg tgcagcccga
    11761 cctgtatttc gggctgggag gtattgcatt cgcattggcg gcttatcacc gggaagtgga
    11821 gcaggggcgt gccgacccgg tagcggggct gggcccggcc atcgatggcg cccttgcggt
    11881 gttccagacc atgtgtgagc agcaccccgc cgagatcgat ggtggattcg tcggaaccgg
    11941 ttcacagata tggacattgc tggcattgca cgacctgttg cagcgaccgg cgttgctggt
    12001 gctggcggaa cgttgtgcgg aagccgcaga gcgtcgcggc ttccaggagg cgacaaagtt
    12061 cgaactgatt gatggcgtgt ccggcatgat cctgccgttg ctgtcgctgg ccgcggctac
    12121 cgggaacgca cgctggctgg agctggccgc cgcagcgggg cgtcgcatgc aggaagcggc
    12181 gatcgtcgat gccgacggcg cacgctggcc gacgccacag ttccgcgagc cgatcggtgg
    12241 cttcggccac ggtgcgatgg gcatgggctg ggcgctggca cggctggcgc gttcggatgc
    12301 cggcagcgtg cctgagcgag cggcctggcg gcagttggct gaaggagcgt ttgcgttcca
    12361 ggcggcgctg ttcgaaccgc ataccgggca ctggcgtgac atccacctgc aggatgggca
    12421 gaagaacttc ccgacctggt gccatggcag cgttggtatc ggtctggcgg cggcggatct
    12481 gtatgcccgc accggcgatc ccgcgcagtt gcgtgacatg cggcgggctg tggccgacgc
    12541 gcgcggcaaa tgggggttca gccacaccct gtgccacggc gatgtgtcca cccgggagct
    12601 gctggtgctg gcggctgcgc tggatccgga gggatgtccc tatccgcagg atgaggcggc
    12661 catcgagatc gtttcttcaa tcgaggagca ccagggcatg gtcggcggac tgacccgcgc
    12721 ggccttcact ccgggcctga tgatcggcct ggcaggtgcg atctatggtt tcctgcgcat
    12781 gcatccggcc tgcgcgctgc cgtcgccgtt gctgcaggag acgacagtgg cccgggtcga
    12841 tgcaccggca tcgcgttcca ttaccgcgca ggaccgagcg gtgctggccg aggtctgagc
    12901 cggacggggc cggccgcgat caacggctgg gatcgcgttc cgggctcggt cgcttggcca
    12961 gcttgcgctg cagcgaacgc cggtgcatgc cgagcaggcg tgcggccgcc gatacgttgc
    13021 caccggtctc gtgcatcgcc tgctggatgt gttcccactg caggcggctg atcggcgtca
    13081 tcgcgtccgg cacttccatt tcgccatcgt cggccgggcc gtcatcttcc tcgccgaggg
    13141 cgcgcaggat catcggcacc gtggccggct tcggcaggta gtcgtcggcg ccgagcttga
    13201 tcgcctccac ggcggtggcg atgctggcgt agccggtcac cagcaggatg cgcatgtccg
    13261 cgcgcagcgc gcgcagtggt tggatcagtg ccaggccgga gtcgctgccc agcttcaggt
    13321 cgatcaacgc gaaggcgggc ggatgctggc gggccaacgc cagtgcgctg gcggcatcct
    13381 gcgcggtctg cgtttccagc cccttgcggg ccaggctgcg ctgcagcgtg cgcaggtaca
    13441 gttcgtcgtc gtcgaccagc aggccgaggg ttgaggcgct catggggttt cctcgcgtag
    13501 ggccagcggc aggcggaagc cgacgcggct gccggcccct tgggccgggc gcatccacat
    13561 ctcgccgtcg aggcgttcga tggtggcatg ggacagggcc aggccgaccc ccatgccttc
    13621 actcttgctg ctgccgaaca gcttgcccgg cagcaccgcg gcgcgcgcgt tgaagccgtg
    13681 gccgtagtca cgcacctcgc cgatcagatc gttgccttcg atgcgcaggt ccaggtccac
    13741 gcgcggccgg ccggcctgtt cgccggcatc ggcggcattg ttgagcagga ccatcagcag
    13801 atggcccacg ccgggatcca gcggcagccg cagcggtgca tcgtcgttgc ggtgcagatc
    13861 gatggtcgga cgcaccagtc gccactgttc cagcacctgc tgggccgtgg ataccgcccg
    13921 gcccgggccg tccgccgagg ccggtgcggc cagcgccagc acacgctcgc ggcactgcac
    13981 cagcaactcg cgcagggttt ccatgtcctc gcgcacttcc ggctcttcac tgcgctcggc
    14041 cacgtcgtcg gcgagcaggg tcatggtggc cagcggtgta ttcagttcgt gcgccaccga
    14101 cgcggcatgg gtcgccaggg cgacgatgcc ctcgttgcgg gcgaagcgtt cgcgcagcgc
    14161 cgacagttcc agttcgcgct ggcgcagcgc cagtgccagg cgggtggaga aggccagcac
    14221 cactgcggcg gaaatcagga aattggcgac cacgccccag cggttgaggt cctgcgcacg
    14281 gaaatagcca tccggcagcg actggccgaa gatgccgctg gcggcgtagc cgagcaggca
    14341 ggccagcgcg accgccagcg cccagcgcag gggcagggcg aaggcggcca gtgcgatcag
    14401 gatcaggaac agtgaactga acgggttggc catgccaccg ctccagccca ccatccaggt
    14461 caggatgatc acatccacca ggatgtggcc gaatgcggtc agcggcgcgg tgtcggccgc
    14521 ttccgggcgc agctgggtat agacgttgaa cagggtcagc acggccacgc cggcccacag
    14581 cggcagctgc ggcaacggca ggcccagcac ccaggtggcg accaggatgg tggcggcctg
    14641 gccacctacg gcaagccagc gcaggctgca cagggttcgg agaaacgggg cgtcgggacc
    14701 ggtcattcac gctcatccta tgcgttcacg cgtgaccgtg cctgcgacaa tcggccgcag
    14761 ccgtgccgcc ggctgaatgc gagtcacccg gaatgcggga gcgggcggta gaatgcgccc
    14821 atgcacgacg ccgtcacccg cccgaccccc ccctccgatg ccacctcctg gccccgccgc
    14881 cagacccatg ccgtgcagat cggcggggtc accgtaggtg gaggcaagcc ggtggtggtg
    14941 cagtcgatga ccaacaccga cacgtccgac gtggcctcca gcgtgaagca ggtggccgag
    15001 ctctggcgtg ccggttcgga aatggtgcgt ttgaccgtca acaccgttga agccgctgcg
    15061 gcgatcccgc gcatcgtcga caagctggcg atgatgggca tcgacgtgcc gctgatcggt
    15121 gacttccatt acaacggcca ccagttgctg accgccgaac cggcgtgtgc cgaagcgctg
    15181 gccaagtacc gcatcaaccc gggcaacgtc ggcttcggca agaaaaagga cctgcagttc
    15241 gcccagctga tcgagttcgc gatccgctac aacaagccgg tgcgcatcgg cgccaactgg
    15301 ggctcgctgg accaggccct ggcggcgaag ctgatggacg agaacaacct gcgcgaacag
    15361 ccctgggacg ccggtcgcgt gctgcgcgag gcgctgatcc gctcggcgct ggattcggcc
    15421 gagcaggcag tggaactcgg cctgccgcgc gaccgcatcg tgctgtcggc caaggtcagc
    15481 ggcgtgcagg agctgatcgc ggtgtaccgc gacctggccc agcgctcgga cttcgccctg
    15541 cacctgggcc tgaccgaggc cggcatcggc agcaagggca tcgtcgcctc gtccgcggcg
    15601 ctgagcgtgc tgctgcagga aggcatcgga gacaccatcc gcatctcgct gaccccggaa
    15661 ccgggccagt cgcgcacgca ggaagtgatc gtcgcccagg aactgctgca gaccaccggc
    15721 cagcgtgcct tcacgccgct ggtcacggcc tgcccgggct gcggccgcac cacctccgag
    15781 ttcttccagg agctggccaa ggtggtgcag aaccacgtgc gcgagaagat gccgctgtgg
    15841 aagatccacc acccgggggc ggagaacatg accctggcgg tgatgggctg catcgtcaac
    15901 gggccgggtg agtcgcgcca tgcgaacatc ggcatctcgt tgccgggcac gggtgaaacg
    15961 cctgcagcgc cggtgttcgt cgatggcgag aagaaggtga ccctgcgtgg cgacaacatc
    16021 gcccaggagt tcgtcgccct gatcgacgat tacgtcgaac acacgtatgt ccgaagcgcc
    16081 ggataagcct gcgatcctcg ctgcaccgga gtccgcctcc ggcttccgcc actggatggc
    16141 gcgcaacgcc tggcgcctgg tcctgctgtt cggcggtgtg ttgctgccgc tggccggctt
    16201 cgtcgccctg gctgacgagg tgcacgagtt tgaatcgttc catttcgacg cgccgctgct
    16261 gtggcagatg catggcctgc attcgccgct gctggaccgc ttcttcatgc tcatctccaa
    16321 actgggctac gaatggttcc tgatcccggc cgacgtgctg atcatcggcg cgctgctggg
    16381 ctaccggcgt tggcgcgagg ccaccttcgt ggcggtcagc ttcgtcggct cggcgctact
    16441 gaacatgggc agcaagcact tcttccagcg ccagcgcccc agcctgtggg aatcgatcgc
    16501 gccggaatcg acgttcagct tccccagcgg ccacgcgatg ggctcgatga ccctggcggt
    16561 gaccctggta ctgctggcct ggaacacccg ctggcgctgg ccggtgctgc tgctggcgcc
    16621 ggcattcagc ctgctggtca gcgtgtcccg ggtctatctg ggggtgcatt acccctccga
    16681 tatcctggcc gggtggtgtg ccgcgctggt ttgggtggta gggtgctatc tggtcatgtt
    16741 cagtcgccgg cacccttggc gacgtcacgg cccgccgcca gcgaaggcca gcgaagcatc
    16801 atcacagggg gattgacgtg gatggccctt gagggacgtc tacgtgatag atcagttgtt
    16861 tcgttgcagc aggttctgca agacaggggg caagcacaac gcgcggtact gtgatgcgca
    16921 gggcagattg ccggggtcgc attccgaacg cgcttgcagg ggtatcggca ccccacctag
    16981 cttgacctgc aatggccgca ttcgaagagg tacgtgaatg acgattcgag tctacctggt
    17041 ggatgaccac gcactggtcc gcaccggtat gaagatgatt ctgtcggggg aaaccgacat
    17101 cgaggtggtg ggcgaagccg agaccggcga ggacgcgctg cgcgaggtcc gccagctgct
    17161 gccggacgta gtgctgtgcg acctgcatct gccgggtgtg agcggcatgg aagtgactga
    17221 gcgcatcgtg cgcagccacc gcaatacccg cgtggtgatc gtgtcggtgc tggaagatgg
    17281 cccgctgccg aagcggctgc tcgaggctgg tgctgccggt tacatcggca agggctgcga
    17341 tgcgcaggag ctgctgcgcg cggtgcgcga cgtggccggt ggccgtcgct acctgggtac
    17401 cagcatcgcg cagaacctgg cgctatcgac ggtggaaggc aacggttcgc cgttcgacag
    17461 cctgtcgccg cgcgagctgg aagtggcgtt gctgctgacc cagggcctgc gccaggaaga
    17521 catcgcccgc cgtctgagcc tgagcgcgaa gacggtgaac acgcataagg cgcggttgtt
    17581 cgagaagatg gggatccacg acaacatcgc gttggcgcgg atggccagcc aatacgggct
    17641 ggtggatccg gcacggccgc tgtaagggat tcggccttcg gtagagccga gcccatgctc
    17701 ggctgcgctt cattccgctg gagtggagcc gagcgtgggc tcggctctac agctgcgttg
    17761 ggctcagtgg ccgcgaacgc gctggatgat cttcgcggcg tcggcggcgc tggcgcgcac
    17821 cttgtcccat tcgccgccgg cgatccagtt gcccggcacc atccacgaac caccaatgca
    17881 gaccacgttc ttctgttcga ggtactcggc ggcggtgttt tcggtgatgc cgccggtcgg
    17941 gcacagcttc aggtcggcga ccgggccggc caggcccttg atcatcgcca ggccacccac
    18001 ggccgtggcc gggaacagct tgcacacgcg gaagccgcgc gcatagagcg acagaagctc
    18061 ggtcggcgtg gccgcacccg gcaccaccgg tagcggcgca gcggccaacg catcggccag
    18121 cgtcggcggc gtaccaggcg tcaccaggaa gtccgcgccc gcatcgatcg actgctgcat
    18181 ctgctccacg gtcagcaccg tgcccgcgcc caccaccaca tccggcagct cgcgcttgag
    18241 catcgccagc gcttccatcg ccaccggtgt ccgcagcgtc agctcgatgg ccggcaagcc
    18301 accttccagc agcgccgcac tgaccgcccg cgcctggtcc agcgtatgaa tcgttaccac
    18361 cggcaggatg cccgccgcat gcaacagctc cgccgccttc acctgatgtt gttcgatacc
    18421 catgcttttg cccttgcctt tgctcttctt gattcagtgg ccgcagcgca gatgacgcgt
    18481 cgggaattgt ccaagggcag tagagcgccc tggccgggac cgtgagcggc atggatgccg
    18541 cgatcgagcc cccatggatg ggtttacggc gtgtcccggc cagggcgctc tactgcccaa
    18601 gccgggaagc ctgccgcggc ttttcgcttc aggcgtcctt cgcctcatgc ggcgctgccg
    18661 ccgccgcggc atcgtgtccc aactcatact ccgcgtcgta atcccacggc ccgccatcag
    18721 ccgccgccgg cccgcacgaa atcgaaatcg ccccctggtc ggccggaccc accacgcggc
    18781 ggttgatcgc gaacaggttg cggcccaggt catgcgcggc cggcgcggtg ttcggcgcca
    18841 gcggacgtgc tgcccattcc gccgcatcca ccagcacttc caacgtgccg gcctcgccat
    18901 ccaggcggat catgtcgccc tcgcggacct tcgccagcgg accgccgcgg gcagcctccg
    18961 gcgtcacgtg gatcgccgcc ggaatcttgc ccgaggcgcc ggacaggcgg ccgtcggtaa
    19021 ccagcgccac gcgccggccc tggttctgca acaggcccag cagcggcgcc agcgaatgca
    19081 gttcgggcat gccgttcgca cgcgggccct ggtagcgcac caccgccaca aaatcctgcg
    19141 gcagcaggcc accggcgtgc agcttgttca acacctgcgg tgcatccacc accaccgccg
    19201 gtgcttcgat cgtgcggtac tgcggcttca ccgccgacag cttgatcagc gacttgccca
    19261 ggttgccgcg cagcaggcgc aggccgccct gatgctcgaa cggattgtcg acaccacgca
    19321 ccacttcgtc atcggcgctg cgttccaggc ccggcagata gaccagctgg ccatcgcgca
    19381 gctgcggttc gcgtgcgtag tcggccatgc cgccacgcgc gacgctgacc aggtcgccat
    19441 gcatcaggcc cgccttgatc agctcgccga acacgaaggc cgggccgcct gcggccgcaa
    19501 aacggttcac gtcggcgtcg ccgttcggat agacgcgggc cagcagcggg atcagctgcg
    19561 acagctcgtc gaagtcgtcc caggtcagca cgatgccggc ggcgcgtgcc acgccgatcc
    19621 aatggatggt gtgattggtc gacccaccgg ttgccatcag cgcgatgacc gcgttgatga
    19681 tcgcgcgctc gtcgatgatc cggcccagcg gacggaagtc atcgcccagc gcggtgatgt
    19741 ccagcgcacg ttcggtggct tcgcgggtca gtgcatcacg cagcggcgtg cccgggttga
    19801 cgaacgacgc acccggcagc tgcacgccca tcgcttccag cagcacctgg ttggaattgg
    19861 cggtgccgta gaaggtgcag gtgccagcgc cgtggtacga cgcggactcg gcttccagaa
    19921 gctcttcgcg ggtagcttcg ccggcggcgt agcgttcgcg cacttcggcc ttctgcttgt
    19981 tcggaatgcc cggggtcatc gggccggccg gcacgaacac cgccggcagg tggccgaagg
    20041 ccagtgcacc gatcagcagg cccggcacga tcttgtcgca cacgccgagg tagacggtgg
    20101 tgtcgaacat gtcgtggctg agaccgatgg cggtcgcctg tgcgatcaca tcgcgcgaga
    20161 acagcgacag ttccatgccg cctcggccct gggtgacgcc gtcgcacatc gccggcacgc
    20221 cgccggccac ctgtgcggtg gcgcccagct cgcgggcgat ttcgcggatc tgctcgggat
    20281 aggtctcgaa cggctggtgc gccgacagca tgtcgttgta cgcggtgatg atgcccaggt
    20341 tcggcgtcac gccaccgcgc aggcggctct tgtcggtgcc gccgcaggcg gcgaatccgt
    20401 gggcgaggtt gccgcagctc aggcggctgc ggaacgggcc ctcacgcagg gaggcatcga
    20461 tcgcggccag ataggcggca cgcgaggcgg cgctgcggcg gatgacacgc tcagtgatgg
    20521 cttgcagttg cggatggagg ctcattggct accggcgttc gtggtggcga gaggcaagcg
    20581 gcggcgcggc gccgccgccg acatcaatca gcccagtgca cgcgcaggcg cgcgccgtcc
    20641 aggttgattg cattgaggat cgggtactgc tgggcgtcgt tgctgtccag cgcctggcgc
    20701 agcacctgca gcttctgctt gccgcgcagc agcagcaggc gctggcggca ctggtccagc
    20761 ccgtgcgggg tcagcgtgat gcgcagcggc cactggttcg cgcccgggca gccggtggcg
    20821 tccagtgccg cgtagggcag ggtgctttcc agtgcgcggg ccaggtcctt cgagcccggg
    20881 aacagcgagg cggtgtggcc gtcgttgccc atgcccagtg ccaccaggct cggcggctgg
    20941 ctgtgctggg cctgcaggtt ggcggtgtaa acgcattccg gcagcggctt tccgatccgt
    21001 accagcggat cgaaatgcgc accttcggcg cgcttgagca ggtgctcgcg caccagccag
    21061 gcgttgctgt cgcgatcctg cggcgacagc cagcgctcgt cggccaggct cacttccacc
    21121 cggtcccagt gcacgtccaa ctcggccagc gcctggtaga ccggcgccgg cgtagttccg
    21181 cccgacagca ggatgcgggc gcggcccact tcgttgatgt cgtggttgag agtctgcgcc
    21241 atctcggcgg ccacggcttc gatccagcca tcggcatcgc cgtgcgggat gaactcgatg
    21301 cggtcgtcgt ggaagctggg gctcatgcgg caactcctgg tgcgtcacgt tcggcgtcgg
    21361 cggcataggc ggcagcgccc agcagtccgg cgtggggatg catcacggcc agcgagggaa
    21421 cccgcgccat gatcgaagag aagcggccct tgtgctcgaa gcgctggcgg aacccggagt
    21481 gctgcagcga atcgagcatc ttcggggtca ggccgccggt caggaacacg ccgtcccagg
    21541 cgccctgggt cagcaccagg tcaccggcga tggcgccgaa caccgcgcag aacacatcca
    21601 cggtgcgcat cgcctgcgga tcgccgtgca gggcgcgcgc ggtcacgtcc accggctgca
    21661 gctggccggg atcgataccg gccatctcgc acaccgcgcg atggatgttg accaggccgg
    21721 ggccgcagat cagtcgctcg ttggagacgc ggccgaactg ctcggacagg atttccagga
    21781 tgcggatctc ctccggagtt cccggcggga agctgacatg gccgccttcg gtttccagcg
    21841 gatagcagcg tccgtggcgc aggatcaggc caccgacacc caggccggta cccgggccga
    21901 tcaccgcgta gttgcgcggc tggcccggct tgcccggcac ccaggcggca ccaccgacct
    21961 ggaccacgtc atcgggctgc agcagtgaaa tcgccatcgc ctgtgcggcg aaatcgttga
    22021 tcaggtgcag ttcgtcgaac ccgagcatcg ctgcggtgcg gctgcgcgag atcacccacg
    22081 gatggttggt gatgcgcgct tcgtcaccat caacgcgacc ggccactgcg aacacgccgc
    22141 ggctggcggt ggcgccgatc tgttccagat ggtggcgcgc ggcatcaccc agcgatggga
    22201 actccgccac cgcgtactcg cggatgctgt ccttctgcag cggtgcgtcc tgcgaggtgt
    22261 cggccagggc gaagcgggcg ttggtgccgc caatgtcggc gaccagcacc ggctgcgagc
    22321 tggcactcat gccgaggctc cgctgtccgg cgcgtccacg ccctgcggca ggaactcgcc
    22381 cgcattgctc gggccccatt ggccggcggg gtagggctcc agcggcagct tggcgtcctt
    22441 ccaggcatcg gccacgctgt cgatccacgc ccaggcggcg cgcacttcgt catcgcgcac
    22501 gaacagcgtg tggttgccgt tgaacgcatc caggaacagg cgctcgtacg cgatgcggcg
    22561 gtgcaggccg gtcggcaccg acagctccag ctccagcggg tgcagttcca gcgcgcccca
    22621 ttccgggccg gccaggctgc tcatcaggcc cagttcgatg ttttcctgcg gctgcagctg
    22681 gaacaccagg cggtttggtg cggcctgcgc gcgctgcggg cgctcgaaca gccagtgggt
    22741 gaccggcttc agcgtgacca ccacgcgggt ggtgcgctcg ggcaggcgct tgccggtgac
    22801 caggtggaac ggcacgccgc tccagcgcca gttgtcgatg tgcgcggtga caccggcgaa
    22861 ggtctccacg tcgctgcctt ccggcggctg gtaggcct
//
