Select genomic region:
Overview
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1.10

### Identified secondary metabolite regions using strictness 'relaxed'

NZ_CP096658.1 (Halorussus gelatinilyticus)

Region | Type | From | To | Similarity Confidence | Most similar known cluster
--- | --- | --- | --- | --- | ---
Region 1 | RiPP-like | 114,957 | 126,777 |
Region 2 | terpene | 423,327 | 443,668 |
Region 3 | terpene-precursor | 1,411,228 | 1,432,070 |
Region 4 | azole-containing-RiPP | 1,561,463 | 1,584,795 |
Region 5 | NI-siderophore | 1,752,324 | 1,781,010 |
Region 6 | terpene | 1,941,096 | 1,961,998 |
Region 7 | terpene | 2,365,042 | 2,385,995 |
Region 8 | lanthipeptide-class-ii | 3,175,523 | 3,198,759 | Medium | archalan α | ribosomal:RiPP
Region 9 | terpene-precursor | 3,200,516 | 3,221,577 |
Region 10 | terpene | 3,295,237 | 3,316,322 |

NZ_CP096658.1 - Region 1 - RiPP-like
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Download region GenBank file
Download region SVG
Location: 114,957 - 126,777 nt. (total: 11,821 nt) Show pHMM detection rules used
RiPP-like: (strepbact or Antimicrobial14 or Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or Bacteriocin_IIi or Lactococcin or Antimicrobial17 or Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or TIGR03795 or TIGR03975 or DUF692 or TIGR01193 or (YcaO or TIGR03604))

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
TTA codons
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
Gene overview
Tailoring
MIBiG comparison
KnownClusterBlast
SubClusterBlast
Gene/CDS overview
A brief tabular summary of genes/CDS features within the region.
Filtering the table will also search biosynthetic profiles and gene function data. If enabled, the overview will then zoom to show the area covered by the filtered selection.
Genes selected in the region drawing above will be marked in the table with an indicator to the left of the gene name.
Filter:
Automatically zoom to filtered/selected features

Identifier | Product | Length | Function | Sequence | NCBI Blast | Filter details
--- | --- | --- | --- | --- | --- | ---
|  | NT | AA |  | NT | AA |  |

No genes match the given filter
Tailoring functions
Tailoring enzymes detected in this region
No tailoring functions detected.
Similar gene clusters
Shows areas that are similar to the current region to a reference database.
Mouseover a score cell in the table to get a breakdown of how the score was calculated.The MIBiG database.
Click on an accession to open that entry in the MIBiG database.
Analysis type:

Reference | RiPP-like | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0002584.2 |  | 0.43 | ribosomal | azolemycin B, azolemycin A, azolemycin D, azolemycin C | Streptomyces sp. FXJ1.264
BGC0001174.4 |  | 0.37 | ribosomal | corynazolicin | Corynebacterium urealyticum DSM 7111
BGC0001753.3 |  | 0.28 | ribosomal | radamycin, globimycin | Streptomyces globisporus subsp. globisporus
BGC0002652.2 |  | 0.26 | other (other), saccharide | cytosaminomycin F, cytosaminomycin G, streptcytosine P, plicacetin, 40551-F, 12F-plicacetin, streptcytosine D, streptcytosine E | Streptomyces sp. SHP22-7
BGC0000953.5 |  | 0.23 | saccharide | amicetin | Streptomyces vinaceusdrappus
BGC0002288.2 |  | 0.22 | NRPS | ashimide A, ashimide B | Streptomyces sp. NA03103
BGC0001379.5 |  | 0.22 | NRPS | BD-12 | Streptomyces luteocolor
BGC0000376.5 |  | 0.20 | NRPS | JBIR-34, JBIR-35 | Streptomyces sp. Sp080513GE-23
BGC0001368.5 |  | 0.20 | NRPS | JBIR-126 | Streptomyces sp. NRRL F-4474

Reference | Aggregated | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0002584.2 |  | 0.43 | ribosomal | azolemycin B, azolemycin A, azolemycin D, azolemycin C | Streptomyces sp. FXJ1.264
BGC0001174.4 |  | 0.37 | ribosomal | corynazolicin | Corynebacterium urealyticum DSM 7111
BGC0001753.3 |  | 0.28 | ribosomal | radamycin, globimycin | Streptomyces globisporus subsp. globisporus
BGC0002652.2 |  | 0.26 | other (other), saccharide | cytosaminomycin F, cytosaminomycin G, streptcytosine P, plicacetin, 40551-F, 12F-plicacetin, streptcytosine D, streptcytosine E | Streptomyces sp. SHP22-7
BGC0000953.5 |  | 0.23 | saccharide | amicetin | Streptomyces vinaceusdrappus
BGC0002288.2 |  | 0.22 | NRPS | ashimide A, ashimide B | Streptomyces sp. NA03103
BGC0001379.5 |  | 0.22 | NRPS | BD-12 | Streptomyces luteocolor
BGC0000376.5 |  | 0.20 | NRPS | JBIR-34, JBIR-35 | Streptomyces sp. Sp080513GE-23
BGC0001368.5 |  | 0.20 | NRPS | JBIR-126 | Streptomyces sp. NRRL F-4474

Similar known clusters from MIBiG 4.0
Shows clusters from the MIBiG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Detailed help and explanations are available here.
Click on reference genes to show details of similarities to genes within the current region.
Double click on a reference drawing to reverse the display of the genes.
Click on an accession to open that entry in the MIBiG database.

No significant matches found.

Similar subclusters
Shows sub-cluster units that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Detailed help and explanations are available here.
Click on reference genes to show details of similarities to genes within the current region.
Double click on a reference drawing to reverse the display of the genes.

No significant matches found.

NZ_CP096658.1 - Region 2 - terpene
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Download region GenBank file
Download region SVG
Location: 423,327 - 443,668 nt. (total: 20,342 nt) Show pHMM detection rules used
terpene: (PT_phytoene_like or phytoene_synt or Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or T2TS or TS_UbiA or TS_Pyr4)

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
TTA codons
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
Gene overview
Tailoring
MIBiG comparison
KnownClusterBlast
SubClusterBlast
Terpene
Gene/CDS overview
A brief tabular summary of genes/CDS features within the region.
Filtering the table will also search biosynthetic profiles and gene function data. If enabled, the overview will then zoom to show the area covered by the filtered selection.
Genes selected in the region drawing above will be marked in the table with an indicator to the left of the gene name.
Filter:
Automatically zoom to filtered/selected features

Identifier | Product | Length | Function | Sequence | NCBI Blast | Filter details
--- | --- | --- | --- | --- | --- | ---
|  | NT | AA |  | NT | AA |  |

No genes match the given filter
Tailoring functions
Tailoring enzymes detected in this region
Translocases: permease
M0R88_RS02265: phenylalanine-specific permease

smcogs
  SMCOG1038: phenylalanine-specific permease

Similar gene clusters
Shows areas that are similar to the current region to a reference database.
Mouseover a score cell in the table to get a breakdown of how the score was calculated.The MIBiG database.
Click on an accession to open that entry in the MIBiG database.
Analysis type:

Reference | terpene | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0001962.3 |  | 0.35 | PKS | hierridin B, hierridin C | Cyanobium sp. LEGE 06113
BGC0000514.5 |  | 0.29 | ribosomal | gallidermin | Staphylococcus gallinarum
BGC0001778.5 |  | 0.29 | other (other) | showdomycin | Streptomyces showdoensis
BGC0000559.4 |  | 0.27 | ribosomal | subtilin | Bacillus subtilis subsp. spizizenii ATCC 6633
BGC0002668.2 |  | 0.26 | ribosomal | cesin A | Clostridium estertheticum
BGC0001594.3 |  | 0.26 | other (other) | fischerindole L | Fischerella muscicola UTEX 1829
BGC0001126.4 |  | 0.25 | other (other), terpene | 12-epi-hapalindole J isonitrile, ambiguine A isonitrile, ambiguine B isonitrile, ambiguine C isonitrile, ambiguine D isonitrile, ambiguine E isonitrile, ambiguine K isonitrile, ambiguine L isonitrile, ambiguine I isonitrile, ambiguine J isonitrile | Fischerella ambigua UTEX 1903
BGC0001501.5 |  | 0.25 | other (other) | ambiguine P | Fischerella sp. TAU
BGC0001612.3 |  | 0.25 | other (other) | ambiguine H isonitrile | Fischerella ambigua UTEX 1903
BGC0001283.3 |  | 0.23 | PKS | Bisenarsan | Streptomyces lividans 1326

Reference | Aggregated | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0001962.3 |  | 0.35 | PKS | hierridin B, hierridin C | Cyanobium sp. LEGE 06113
BGC0000514.5 |  | 0.29 | ribosomal | gallidermin | Staphylococcus gallinarum
BGC0001778.5 |  | 0.29 | other (other) | showdomycin | Streptomyces showdoensis
BGC0000559.4 |  | 0.27 | ribosomal | subtilin | Bacillus subtilis subsp. spizizenii ATCC 6633
BGC0002668.2 |  | 0.26 | ribosomal | cesin A | Clostridium estertheticum
BGC0001594.3 |  | 0.26 | other (other) | fischerindole L | Fischerella muscicola UTEX 1829
BGC0001126.4 |  | 0.25 | other (other), terpene | 12-epi-hapalindole J isonitrile, ambiguine A isonitrile, ambiguine B isonitrile, ambiguine C isonitrile, ambiguine D isonitrile, ambiguine E isonitrile, ambiguine K isonitrile, ambiguine L isonitrile, ambiguine I isonitrile, ambiguine J isonitrile | Fischerella ambigua UTEX 1903
BGC0001501.5 |  | 0.25 | other (other) | ambiguine P | Fischerella sp. TAU
BGC0001612.3 |  | 0.25 | other (other) | ambiguine H isonitrile | Fischerella ambigua UTEX 1903
BGC0001283.3 |  | 0.23 | PKS | Bisenarsan | Streptomyces lividans 1326

Similar known clusters from MIBiG 4.0
Shows clusters from the MIBiG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Detailed help and explanations are available here.
Click on reference genes to show details of similarities to genes within the current region.
Double click on a reference drawing to reverse the display of the genes.
Click on an accession to open that entry in the MIBiG database.

No significant matches found.

Similar subclusters
Shows sub-cluster units that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Detailed help and explanations are available here.
Click on reference genes to show details of similarities to genes within the current region.
Double click on a reference drawing to reverse the display of the genes.

No significant matches found.

Detailed terpene predictions
Detailed information for terpene domains. Shows possible products of a terpene cluster and lists the subtype and expected reactions for each terpene-related domain.
Product predictions:

Class | Subclass | Product name | Chain length | Initial cyclisations | Functional groups
--- | --- | --- | --- | --- | ---
tetraterpene | C40 carotenoid |  | C40 | unknown | unknown

Genes with terpene domains:
M0R88_RS02245: Lycopene_cycl
Domain 1 (12 - 91): Lycopene cyclase

Reactions:
  C40_carotenoid → C40_carotenoid

Terpene
Glossary
Glossary showing acronyms and their full names.
No acronyms to display
NZ_CP096658.1 - Region 3 - terpene-precursor
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Download region GenBank file
Download region SVG
Location: 1,411,228 - 1,432,070 nt. (total: 20,843 nt) Show pHMM detection rules used
terpene-precursor: (PT_FPPS_like and not PT_HPP)

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
TTA codons
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
Gene overview
Tailoring
MIBiG comparison
KnownClusterBlast
SubClusterBlast
Terpene
Gene/CDS overview
A brief tabular summary of genes/CDS features within the region.
Filtering the table will also search biosynthetic profiles and gene function data. If enabled, the overview will then zoom to show the area covered by the filtered selection.
Genes selected in the region drawing above will be marked in the table with an indicator to the left of the gene name.
Filter:
Automatically zoom to filtered/selected features

Identifier | Product | Length | Function | Sequence | NCBI Blast | Filter details
--- | --- | --- | --- | --- | --- | ---
|  | NT | AA |  | NT | AA |  |

No genes match the given filter
Tailoring functions
Tailoring enzymes detected in this region
Transferases: methyltransferase
M0R88_RS07415: methyltransferase

smcogs
  SMCOG1089: methyltransferase

Hydrolases: protease
M0R88_RS07385: alkaline serine protease, subtilase family

smcogs
  SMCOG1075: alkaline serine protease, subtilase family

Ligases: synthetase
M0R88_RS07370: Polyprenyl synthetase

smcogs
  SMCOG1182: Polyprenyl synthetase

Similar gene clusters
Shows areas that are similar to the current region to a reference database.
Mouseover a score cell in the table to get a breakdown of how the score was calculated.The MIBiG database.
Click on an accession to open that entry in the MIBiG database.
Analysis type:

Reference | terpene-precursor | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0002162.3 |  | 0.50 | terpene | sesterfisherol, sesterfisheric acid, compound 6, compound 7a, compound 5, compound 8 | Aspergillus fischeri NRRL 181
BGC0002736.2 |  | 0.49 | terpene | preaspterpenacid I | Aspergillus terreus NIH2624
BGC0002610.3 |  | 0.49 | terpene | stellatic acid | Aspergillus stellatus
BGC0000244.4 |  | 0.41 | PKS | nonactin, monactin, dinactin, trinactin, tetranactin | Streptomyces griseus subsp. griseus
BGC0001528.4 |  | 0.40 | terpene | betaestacin I, betaestacin II | Phoma betae
BGC0002219.2 |  | 0.39 | terpene | (-)-(R)-nephthenol | Stereum hirsutum FP-91666 SS1
BGC0000646.5 |  | 0.38 | terpene | β-carotein | uncultured bacterium
BGC0000641.3 |  | 0.37 | terpene | carotenoid | Enterobacteriaceae bacterium DC416
BGC0000639.3 |  | 0.37 | terpene | carotenoid | Enterobacteriaceae bacterium DC260
BGC0000642.3 |  | 0.37 | terpene | carotenoid | Enterobacteriaceae bacterium DC413

Reference | Aggregated | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0002162.3 |  | 0.50 | terpene | sesterfisherol, sesterfisheric acid, compound 6, compound 7a, compound 5, compound 8 | Aspergillus fischeri NRRL 181
BGC0002736.2 |  | 0.49 | terpene | preaspterpenacid I | Aspergillus terreus NIH2624
BGC0002610.3 |  | 0.49 | terpene | stellatic acid | Aspergillus stellatus
BGC0000244.4 |  | 0.41 | PKS | nonactin, monactin, dinactin, trinactin, tetranactin | Streptomyces griseus subsp. griseus
BGC0001528.4 |  | 0.40 | terpene | betaestacin I, betaestacin II | Phoma betae
BGC0002219.2 |  | 0.39 | terpene | (-)-(R)-nephthenol | Stereum hirsutum FP-91666 SS1
BGC0000646.5 |  | 0.38 | terpene | β-carotein | uncultured bacterium
BGC0000641.3 |  | 0.37 | terpene | carotenoid | Enterobacteriaceae bacterium DC416
BGC0000639.3 |  | 0.37 | terpene | carotenoid | Enterobacteriaceae bacterium DC260
BGC0000642.3 |  | 0.37 | terpene | carotenoid | Enterobacteriaceae bacterium DC413

Similar known clusters from MIBiG 4.0
Shows clusters from the MIBiG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Detailed help and explanations are available here.
Click on reference genes to show details of similarities to genes within the current region.
Double click on a reference drawing to reverse the display of the genes.
Click on an accession to open that entry in the MIBiG database.

No significant matches found.

Similar subclusters
Shows sub-cluster units that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Detailed help and explanations are available here.
Click on reference genes to show details of similarities to genes within the current region.
Double click on a reference drawing to reverse the display of the genes.

No significant matches found.

Detailed terpene predictions
Detailed information for terpene domains. Shows possible products of a terpene cluster and lists the subtype and expected reactions for each terpene-related domain.
Product predictions:

Class | Subclass | Product name | Chain length | Initial cyclisations | Functional groups
--- | --- | --- | --- | --- | ---
sesquiterpene precursor |  | FPP | C15 | acyclic | PP
diterpene precursor |  | GGPP | C20 | acyclic | PP
sesterterpene precursor |  | GFPP | C25 | acyclic | PP
triterpene precursor |  | HPP | C30 | acyclic | PP

Genes with terpene domains:
M0R88_RS07370: PT_FPPS_like
Domain 1 (28 - 238): Prenyltransferase; Farnesyl diphosphate synthase like
Subtype: unknown

Reactions:
  IPP, DMAPP → FPP
  IPP, DMAPP → GGPP
  IPP, DMAPP → GFPP
  IPP, DMAPP → HPP

Terpene
Glossary
Glossary showing acronyms and their full names.

Acronym | Full name
--- | ---
DMAPP | Dimethylallyl diphosphate
FPP | Farnesyl diphosphate
GFPP | Geranylfarnesyl diphosphate
GGPP | Geranylgeranyl diphosphate
HPP | Hexaprenyl diphosphate
IPP | Isopentenyl diphosphate
PP | Diphosphate

NZ_CP096658.1 - Region 4 - azole-containing-RiPP
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Download region GenBank file
Download region SVG
Location: 1,561,463 - 1,584,795 nt. (total: 23,333 nt) Show pHMM detection rules used
azole-containing-RiPP: ((YcaO or TIGR03604) and (((thio_amide and (PF06968 or PF04055 or PF07366)) or Lant_dehydr_C or Lant_dehydr_N or (PF06968 or PF04055 or PF07366)) or (goadsporin_like or PF00881 or TIGR03605)) or TIGR03882 or TIGR03603 or thiostrepton or TIGR03602)

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
TTA codons
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
Gene overview
Tailoring
MIBiG comparison
KnownClusterBlast
SubClusterBlast
Azole RiPPs
Gene/CDS overview
A brief tabular summary of genes/CDS features within the region.
Filtering the table will also search biosynthetic profiles and gene function data. If enabled, the overview will then zoom to show the area covered by the filtered selection.
Genes selected in the region drawing above will be marked in the table with an indicator to the left of the gene name.
Filter:
Automatically zoom to filtered/selected features

Identifier | Product | Length | Function | Sequence | NCBI Blast | Filter details
--- | --- | --- | --- | --- | --- | ---
|  | NT | AA |  | NT | AA |  |

No genes match the given filter
Tailoring functions
Tailoring enzymes detected in this region
Oxidoreductases: dehydrogenase
M0R88_RS08105: short-chain dehydrogenase/reductase SDR

smcogs
  SMCOG1001: short-chain dehydrogenase/reductase SDR

Similar gene clusters
Shows areas that are similar to the current region to a reference database.
Mouseover a score cell in the table to get a breakdown of how the score was calculated.The MIBiG database.
Click on an accession to open that entry in the MIBiG database.
Analysis type:

Reference | azole-containing-RiPP | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0001174.4 |  | 0.50 | ribosomal | corynazolicin | Corynebacterium urealyticum DSM 7111
BGC0002013.4 |  | 0.47 | ribosomal | curacozole | Streptomyces curacoi
BGC0000568.5 |  | 0.47 | ribosomal | microcin B17 | Escherichia coli
BGC0001173.5 |  | 0.45 | ribosomal | plantazolicin | Bacillus pumilus ATCC 7061
BGC0000569.5 |  | 0.45 | ribosomal | plantazolicin | Bacillus velezensis FZB42
BGC0001170.5 |  | 0.42 | ribosomal | clostridiolysin S | Clostridium sporogenes ATCC 15579
BGC0000564.5 |  | 0.42 | ribosomal | clostridiolysin S | Clostridium botulinum A str. ATCC 3502
BGC0001618.3 |  | 0.40 | ribosomal | hyicin 3682 | Staphylococcus hyicus
BGC0000477.3 |  | 0.39 | ribosomal | patellin 2, patellin 3 | uncultured Prochloron sp. 06037A
BGC0002111.3 |  | 0.39 | ribosomal | andalusicin A, andalusicin B | Bacillus thuringiensis serovar andalousiensis NRRL B-23139

Reference | Aggregated | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0001174.4 |  | 0.50 | ribosomal | corynazolicin | Corynebacterium urealyticum DSM 7111
BGC0002013.4 |  | 0.47 | ribosomal | curacozole | Streptomyces curacoi
BGC0000568.5 |  | 0.47 | ribosomal | microcin B17 | Escherichia coli
BGC0001173.5 |  | 0.45 | ribosomal | plantazolicin | Bacillus pumilus ATCC 7061
BGC0000569.5 |  | 0.45 | ribosomal | plantazolicin | Bacillus velezensis FZB42
BGC0001170.5 |  | 0.42 | ribosomal | clostridiolysin S | Clostridium sporogenes ATCC 15579
BGC0000564.5 |  | 0.42 | ribosomal | clostridiolysin S | Clostridium botulinum A str. ATCC 3502
BGC0001618.3 |  | 0.40 | ribosomal | hyicin 3682 | Staphylococcus hyicus
BGC0000477.3 |  | 0.39 | ribosomal | patellin 2, patellin 3 | uncultured Prochloron sp. 06037A
BGC0002111.3 |  | 0.39 | ribosomal | andalusicin A, andalusicin B | Bacillus thuringiensis serovar andalousiensis NRRL B-23139

Similar known clusters from MIBiG 4.0
Shows clusters from the MIBiG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Detailed help and explanations are available here.
Click on reference genes to show details of similarities to genes within the current region.
Double click on a reference drawing to reverse the display of the genes.
Click on an accession to open that entry in the MIBiG database.

No significant matches found.

Similar subclusters
Shows sub-cluster units that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Detailed help and explanations are available here.
Click on reference genes to show details of similarities to genes within the current region.
Double click on a reference drawing to reverse the display of the genes.

No significant matches found.

(Thi)azol(in)e containing peptide predictions
Lists the possible core peptides for each biosynthetic enzyme. Predicted tail sequences are also shown, if present.
Includes CompaRiPPson results for any available databases, with a detailed explanation here.
No core peptides found.
Azole RiPPs
Core peptide predictions
Lists the possible core peptides in the region. Each core peptide lists its possible molecular weights and the scores for cleavage site prediction and RODEO. If relevant, other features, such as macrocycle and amidation, will also be listed.
No core peptides found.
NZ_CP096658.1 - Region 5 - NI-siderophore
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Download region GenBank file
Download region SVG
Location: 1,752,324 - 1,781,010 nt. (total: 28,687 nt) Show pHMM detection rules used
NI-siderophore: IucA_IucC

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
TTA codons
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
Gene overview
Tailoring
MIBiG comparison
KnownClusterBlast
SubClusterBlast
Gene/CDS overview
A brief tabular summary of genes/CDS features within the region.
Filtering the table will also search biosynthetic profiles and gene function data. If enabled, the overview will then zoom to show the area covered by the filtered selection.
Genes selected in the region drawing above will be marked in the table with an indicator to the left of the gene name.
Filter:
Automatically zoom to filtered/selected features

Identifier | Product | Length | Function | Sequence | NCBI Blast | Filter details
--- | --- | --- | --- | --- | --- | ---
|  | NT | AA |  | NT | AA |  |

No genes match the given filter
Tailoring functions
Tailoring enzymes detected in this region
Oxidoreductases: oxidoreductase reductase
M0R88_RS09140: aldo/keto reductase family oxidoreductase

smcogs
  SMCOG1039: aldo/keto reductase family oxidoreductase

M0R88_RS09150: alkyl hydroperoxide reductase subunit

smcogs
  SMCOG1176: alkyl hydroperoxide reductase subunit

Similar gene clusters
Shows areas that are similar to the current region to a reference database.
Mouseover a score cell in the table to get a breakdown of how the score was calculated.The MIBiG database.
Click on an accession to open that entry in the MIBiG database.
Analysis type:

Reference | NI-siderophore | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0002073.3 |  | 0.51 | NRPS | dehydroxynocardamine | Corynebacterium propinquum
BGC0000584.5 |  | 0.47 | ribosomal | colicin V | Escherichia coli
BGC0000939.5 |  | 0.44 | other (other) | aerobactin | Grimontia hollisae
BGC0002682.2 |  | 0.44 | other (other) | aerobactin | Vibrio mimicus
BGC0000295.5 |  | 0.44 | NRPS | acinetoferrin | Acinetobacter haemolyticus
BGC0001870.3 |  | 0.43 | other (other) | putrebactin, avaroferrin | Xenorhabdus budapestensis
BGC0002306.2 |  | 0.42 | ribosomal | freyrasin | Paenibacillus polymyxa ATCC 842
BGC0000551.5 |  | 0.42 | ribosomal | SapB | Streptomyces coelicolor A3(2)
BGC0001555.4 |  | 0.42 | ribosomal | colicin V | Escherichia coli chi7122
BGC0000558.5 |  | 0.42 | ribosomal | sublancin 168 | Bacillus subtilis subsp. subtilis str. 168

Reference | Aggregated | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0002073.3 |  | 0.51 | NRPS | dehydroxynocardamine | Corynebacterium propinquum
BGC0000584.5 |  | 0.47 | ribosomal | colicin V | Escherichia coli
BGC0000939.5 |  | 0.44 | other (other) | aerobactin | Grimontia hollisae
BGC0002682.2 |  | 0.44 | other (other) | aerobactin | Vibrio mimicus
BGC0000295.5 |  | 0.44 | NRPS | acinetoferrin | Acinetobacter haemolyticus
BGC0001870.3 |  | 0.43 | other (other) | putrebactin, avaroferrin | Xenorhabdus budapestensis
BGC0002306.2 |  | 0.42 | ribosomal | freyrasin | Paenibacillus polymyxa ATCC 842
BGC0000551.5 |  | 0.42 | ribosomal | SapB | Streptomyces coelicolor A3(2)
BGC0001555.4 |  | 0.42 | ribosomal | colicin V | Escherichia coli chi7122
BGC0000558.5 |  | 0.42 | ribosomal | sublancin 168 | Bacillus subtilis subsp. subtilis str. 168

Similar known clusters from MIBiG 4.0
Shows clusters from the MIBiG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Detailed help and explanations are available here.
Click on reference genes to show details of similarities to genes within the current region.
Double click on a reference drawing to reverse the display of the genes.
Click on an accession to open that entry in the MIBiG database.

No significant matches found.

Similar subclusters
Shows sub-cluster units that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Detailed help and explanations are available here.
Click on reference genes to show details of similarities to genes within the current region.
Double click on a reference drawing to reverse the display of the genes.

No significant matches found.

NZ_CP096658.1 - Region 6 - terpene
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Download region GenBank file
Download region SVG
Location: 1,941,096 - 1,961,998 nt. (total: 20,903 nt) Show pHMM detection rules used
terpene: (PT_phytoene_like or phytoene_synt or Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or T2TS or TS_UbiA or TS_Pyr4)

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
TTA codons
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
Gene overview
Tailoring
MIBiG comparison
KnownClusterBlast
SubClusterBlast
Terpene
Gene/CDS overview
A brief tabular summary of genes/CDS features within the region.
Filtering the table will also search biosynthetic profiles and gene function data. If enabled, the overview will then zoom to show the area covered by the filtered selection.
Genes selected in the region drawing above will be marked in the table with an indicator to the left of the gene name.
Filter:
Automatically zoom to filtered/selected features

Identifier | Product | Length | Function | Sequence | NCBI Blast | Filter details
--- | --- | --- | --- | --- | --- | ---
|  | NT | AA |  | NT | AA |  |

No genes match the given filter
Tailoring functions
Tailoring enzymes detected in this region
Oxidoreductases: dehydrogenase reductase
M0R88_RS10065: alcohol dehydrogenase

smcogs
  SMCOG1040: alcohol dehydrogenase

M0R88_RS10145: alkyl hydroperoxide reductase/ Thiol specific

smcogs
  SMCOG1196: alkyl hydroperoxide reductase/ Thiol specific

Transferases: glycosyltransferase methyltransferase
M0R88_RS10025: methyltransferase

smcogs
  SMCOG1089: methyltransferase

M0R88_RS10055: glycosyl transferase group 1

smcogs
  SMCOG1045: glycosyl transferase group 1

Similar gene clusters
Shows areas that are similar to the current region to a reference database.
Mouseover a score cell in the table to get a breakdown of how the score was calculated.The MIBiG database.
Click on an accession to open that entry in the MIBiG database.
Analysis type:

Reference | terpene | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0002354.4 |  | 0.37 | other (other) | huimycin | Kutzneria albida DSM 43870
BGC0001387.5 |  | 0.32 | other (other) | nucleocidin | Streptomyces calvus
BGC0001875.4 |  | 0.24 | PKS | nargenicin A1 | Nocardia arthritidis AUSMDU00012717 Unclassified.

Reference | Aggregated | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0002354.4 |  | 0.37 | other (other) | huimycin | Kutzneria albida DSM 43870
BGC0001387.5 |  | 0.32 | other (other) | nucleocidin | Streptomyces calvus
BGC0001875.4 |  | 0.24 | PKS | nargenicin A1 | Nocardia arthritidis AUSMDU00012717 Unclassified.

Similar known clusters from MIBiG 4.0
Shows clusters from the MIBiG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Detailed help and explanations are available here.
Click on reference genes to show details of similarities to genes within the current region.
Double click on a reference drawing to reverse the display of the genes.
Click on an accession to open that entry in the MIBiG database.

No significant matches found.

Similar subclusters
Shows sub-cluster units that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Detailed help and explanations are available here.
Click on reference genes to show details of similarities to genes within the current region.
Double click on a reference drawing to reverse the display of the genes.

No significant matches found.

Detailed terpene predictions
Detailed information for terpene domains. Shows possible products of a terpene cluster and lists the subtype and expected reactions for each terpene-related domain.
Product predictions:

Class | Subclass | Product name | Chain length | Initial cyclisations | Functional groups
--- | --- | --- | --- | --- | ---
tetraterpene | C40 carotenoid |  | C40 | unknown | unknown

Genes with terpene domains:
M0R88_RS10075: Lycopene_cycl + Lycopene_cycl
Domain 1 (6 - 97): Lycopene cyclase

Reactions:
  C40_carotenoid → C40_carotenoid

Domain 2 (156 - 244): Lycopene cyclase

Reactions:
  C40_carotenoid → C40_carotenoid

Terpene
Glossary
Glossary showing acronyms and their full names.
No acronyms to display
NZ_CP096658.1 - Region 7 - terpene
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Download region GenBank file
Download region SVG
Location: 2,365,042 - 2,385,995 nt. (total: 20,954 nt) Show pHMM detection rules used
terpene: (PT_phytoene_like or phytoene_synt or Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or T2TS or TS_UbiA or TS_Pyr4)

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
TTA codons
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
Gene overview
Tailoring
MIBiG comparison
KnownClusterBlast
SubClusterBlast
Terpene
Gene/CDS overview
A brief tabular summary of genes/CDS features within the region.
Filtering the table will also search biosynthetic profiles and gene function data. If enabled, the overview will then zoom to show the area covered by the filtered selection.
Genes selected in the region drawing above will be marked in the table with an indicator to the left of the gene name.
Filter:
Automatically zoom to filtered/selected features

Identifier | Product | Length | Function | Sequence | NCBI Blast | Filter details
--- | --- | --- | --- | --- | --- | ---
|  | NT | AA |  | NT | AA |  |

No genes match the given filter
Tailoring functions
Tailoring enzymes detected in this region
Hydrolases: deacetylase
M0R88_RS12235: acetylornithine deacetylase

smcogs
  SMCOG1247: acetylornithine deacetylase

Lyases: decarboxylase lyase
M0R88_RS12220: argininosuccinate lyase/adenylosuccinate lyase

smcogs
  SMCOG1063: argininosuccinate lyase/adenylosuccinate lyase

M0R88_RS12245: diaminopimelate decarboxylase

smcogs
  SMCOG1264: diaminopimelate decarboxylase

Similar gene clusters
Shows areas that are similar to the current region to a reference database.
Mouseover a score cell in the table to get a breakdown of how the score was calculated.The MIBiG database.
Click on an accession to open that entry in the MIBiG database.
Analysis type:

Reference | terpene | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0000645.3 |  | 0.42 | terpene | carotenoid | Halobacillus halophilus DSM 2266
BGC0002645.3 |  | 0.41 | other (other) | fluopsin C | Pseudomonas aeruginosa PAO1
BGC0000664.5 |  | 0.40 | terpene | isorenieratene | Streptomyces griseus subsp. griseus NBRC 13350
BGC0000633.3 |  | 0.40 | terpene | carotenoid | Streptomyces avermitilis
BGC0001227.3 |  | 0.39 | terpene | isorenieratene | Streptomyces collinus Tu 365
BGC0001456.3 |  | 0.39 | terpene | isorenieratene | Streptomyces argillaceus
BGC0001778.5 |  | 0.39 | other (other) | showdomycin | Streptomyces showdoensis
BGC0000648.3 |  | 0.37 | terpene | carotenoid | Myxococcus xanthus
BGC0000663.5 |  | 0.36 | terpene | hopene | Streptomyces coelicolor A3(2)
BGC0000494.5 |  | 0.33 | ribosomal | uberolysin | Streptococcus uberis

Reference | Aggregated | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0000645.3 |  | 0.42 | terpene | carotenoid | Halobacillus halophilus DSM 2266
BGC0002645.3 |  | 0.41 | other (other) | fluopsin C | Pseudomonas aeruginosa PAO1
BGC0000664.5 |  | 0.40 | terpene | isorenieratene | Streptomyces griseus subsp. griseus NBRC 13350
BGC0000633.3 |  | 0.40 | terpene | carotenoid | Streptomyces avermitilis
BGC0001227.3 |  | 0.39 | terpene | isorenieratene | Streptomyces collinus Tu 365
BGC0001456.3 |  | 0.39 | terpene | isorenieratene | Streptomyces argillaceus
BGC0001778.5 |  | 0.39 | other (other) | showdomycin | Streptomyces showdoensis
BGC0000648.3 |  | 0.37 | terpene | carotenoid | Myxococcus xanthus
BGC0000663.5 |  | 0.36 | terpene | hopene | Streptomyces coelicolor A3(2)
BGC0000494.5 |  | 0.33 | ribosomal | uberolysin | Streptococcus uberis

Similar known clusters from MIBiG 4.0
Shows clusters from the MIBiG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Detailed help and explanations are available here.
Click on reference genes to show details of similarities to genes within the current region.
Double click on a reference drawing to reverse the display of the genes.
Click on an accession to open that entry in the MIBiG database.

No significant matches found.

Similar subclusters
Shows sub-cluster units that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Detailed help and explanations are available here.
Click on reference genes to show details of similarities to genes within the current region.
Double click on a reference drawing to reverse the display of the genes.

No significant matches found.

Detailed terpene predictions
Detailed information for terpene domains. Shows possible products of a terpene cluster and lists the subtype and expected reactions for each terpene-related domain.
Product predictions:

Class | Subclass | Product name | Chain length | Initial cyclisations | Functional groups
--- | --- | --- | --- | --- | ---
triterpene | C30 carotenoid | diapophytoene | C30 | acyclic | none
triterpene |  | squalene | C30 | acyclic | none
triterpene |  | PSPP | C30 | acyclic | PP
tetraterpene | C40 carotenoid | phytoene | C40 | acyclic | none
triterpene |  | hydroxysqualene | C30 | acyclic | OH

Genes with terpene domains:
M0R88_RS12210: PT_phytoene_like
Domain 1 (8 - 282): Prenyltransferase; Phytoene synthase like
Subtype: unknown

Reactions:
  FPP → diapophytoene
  FPP → squalene
  FPP → PSPP
  GGPP → phytoene
  PSPP → hydroxysqualene

Terpene
Glossary
Glossary showing acronyms and their full names.

Acronym | Full name
--- | ---
FPP | Farnesyl diphosphate
GGPP | Geranylgeranyl diphosphate
PP | Diphosphate
PSPP | Presqualene diphosphate

NZ_CP096658.1 - Region 8 - lanthipeptide-class-ii
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Download region GenBank file
Download region SVG
Location: 3,175,523 - 3,198,759 nt. (total: 23,237 nt) Show pHMM detection rules used
lanthipeptide-class-ii: cds(LANC_like and DUF4135)

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
TTA codons
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
Gene overview
Tailoring
MIBiG comparison
KnownClusterBlast
SubClusterBlast
Lanthipeptides
Gene/CDS overview
A brief tabular summary of genes/CDS features within the region.
Filtering the table will also search biosynthetic profiles and gene function data. If enabled, the overview will then zoom to show the area covered by the filtered selection.
Genes selected in the region drawing above will be marked in the table with an indicator to the left of the gene name.
Filter:
Automatically zoom to filtered/selected features

Identifier | Product | Length | Function | Sequence | NCBI Blast | Filter details
--- | --- | --- | --- | --- | --- | ---
|  | NT | AA |  | NT | AA |  |

No genes match the given filter
Tailoring functions
Tailoring enzymes detected in this region
Lyases: cyclase
M0R88_RS16215: lanthionine synthetase C family protein

smcogs
  SMCOG1070: lanthionine synthetase C family protein

Similar gene clusters
Shows areas that are similar to the current region to a reference database.
Mouseover a score cell in the table to get a breakdown of how the score was calculated.The MIBiG database.
Click on an accession to open that entry in the MIBiG database.
Analysis type:

Reference | lanthipeptide-class-ii | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0002703.2 |  | 0.61 | ribosomal | archalan α | Halorussus salinus
BGC0000525.5 |  | 0.50 | ribosomal | lichenicidin VK21 A1, lichenicidin VK21 A2 | Bacillus licheniformis
BGC0002704.2 |  | 0.47 | ribosomal | archalan β | Halorussus salinus
BGC0000554.4 |  | 0.42 | ribosomal | SRO15-3108 | Streptomyces filamentosus NRRL 15998
BGC0000504.5 |  | 0.42 | ribosomal | cytolysin ClyLl, cytolysin ClyLs | Plasmid pAD1
BGC0002698.2 |  | 0.39 | ribosomal | phaeornamide | Pseudophaeobacter arcticus DSM 23566
BGC0002699.2 |  | 0.38 | ribosomal | nostolysamide A, nostolysamide B | Nostoc punctiforme PCC 73102
BGC0002330.2 |  | 0.33 | ribosomal | landornamide A | Kamptonema sp. PCC 6506
BGC0000881.3 |  | 0.27 | other (other) | toyocamycin | Streptomyces ahygroscopicus subsp. wuzhouensis
BGC0001808.5 |  | 0.27 | other (other) | toyocamycin | Streptomyces diastatochromogenes

Reference | Aggregated | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0002703.2 |  | 0.61 | ribosomal | archalan α | Halorussus salinus
BGC0000525.5 |  | 0.50 | ribosomal | lichenicidin VK21 A1, lichenicidin VK21 A2 | Bacillus licheniformis
BGC0002704.2 |  | 0.47 | ribosomal | archalan β | Halorussus salinus
BGC0000554.4 |  | 0.42 | ribosomal | SRO15-3108 | Streptomyces filamentosus NRRL 15998
BGC0000504.5 |  | 0.42 | ribosomal | cytolysin ClyLl, cytolysin ClyLs | Plasmid pAD1
BGC0002698.2 |  | 0.39 | ribosomal | phaeornamide | Pseudophaeobacter arcticus DSM 23566
BGC0002699.2 |  | 0.38 | ribosomal | nostolysamide A, nostolysamide B | Nostoc punctiforme PCC 73102
BGC0002330.2 |  | 0.33 | ribosomal | landornamide A | Kamptonema sp. PCC 6506
BGC0000881.3 |  | 0.27 | other (other) | toyocamycin | Streptomyces ahygroscopicus subsp. wuzhouensis
BGC0001808.5 |  | 0.27 | other (other) | toyocamycin | Streptomyces diastatochromogenes

Similar known clusters from MIBiG 4.0
Shows clusters from the MIBiG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Detailed help and explanations are available here.
Click on reference genes to show details of similarities to genes within the current region.
Double click on a reference drawing to reverse the display of the genes.
Click on an accession to open that entry in the MIBiG database.
Location:
Identifier
Identity
Coverage
Similar subclusters
Shows sub-cluster units that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Detailed help and explanations are available here.
Click on reference genes to show details of similarities to genes within the current region.
Double click on a reference drawing to reverse the display of the genes.

No significant matches found.

Lanthipeptide predictions
Shows the possible core peptides for each biosynthetic enzyme.
Includes CompaRiPPson results for any available databases, with a detailed explanation here.

#### Lanthipeptide(s) for M0R88_RS16215

M0R88_RS16185
Leader:
MADNRVVQGRMVTPEALAELIEGEDVMDA
Core:
E A I S E T D R E C P D C G G D V L E V G Y M P S V T E F V T G W K C Q D C D W A D T D R D
Core with dehydrations:
E A I Dha E Dhb D R E Cys P D Cys G G D V L E V G Y M P Dha V Dhb E F V Dhb G W K Cys Q D Cys D W A D Dhb D R D

#### antiSMASH-DB 4.0 matches for M0R88_RS16185

100.0%
NZ_CP096658.1 and 1 other:
NZ_ML974127.1 Lanthipeptides: EPL00_RS07765_lanthipeptide
Lanthipeptides: M0R88_RS16185_lanthipeptide
1
E A I S E T D R E C P D C G G D V L E V G Y M P S V T E F V T G W K C Q D C D W A D T D R D
46
E A I S E T D R E C P D C G G D V L E V G Y M P S V T E F V T G W K C Q D C D W A D T D R D
1
E A I S E T D R E C P D C G G D V L E V G Y M P S V T E F V T G W K C Q D C D W A D T D R D
46
84.8%
NZ_CP119804.1:
Lanthipeptides: P2T57_RS03940_lanthipeptide
1
E A I S E T D R E C P D C G G D V L E V G Y M P S V T E F V T G W K C Q D C D W A D T D R D
46
E+I +T D R E C P D C G D V L E V G Y M P S V T E F V T G W K C Q+C D W+D T D R+
1
E S I E D T D R E C P D C G E D V L E V G Y M P S V T E F V T G W K C Q E C D W S D T D R E
46
78.3%
NZ_CP096019.1:
Lanthipeptides: MW046_RS07480_lanthipeptide
1
E A I S E T D R E C P D C G G D V L E V G Y M P S V T E F V T G W K C Q D C D W A D T D R D
46
E+I S+T D R E C P D C G G V+ V G Y M P S V E F V T G+K C Q D C D W T D R+
1
E S I S D T D R E C P D C G G P V V S V G Y M P S V M E F V T G Y K C Q D C D W K A T D R E
46
with 2 more sequence matches
15.2%
NZ_ML974127.1:
Lanthipeptides: EPL00_RS07380_lanthipeptide
9
E C P D C G G D V L E V
20
+C P D C G G + V
19
K C P D C G G A L T F V
30
13.0%
NZ_CP096019.1:
Lanthipeptides: allorf_1444717_1444914_lanthipeptide
10
C P D C G G D V L E
19
C P+C G G +E
15
C P E C G G Y A I E
24

#### MIBiG 4.0 matches for M0R88_RS16185

8.7%
BGC0000582.4 (ADR72962.1):
Linaridin: cypemycin
24
P S V T E F V
30
P+V +F V
6
P T V A Q F V
12
allorf_3178073_3178228
Leader:
MELSGARTQLSPAMSGFETYTCENCGDEFEAHESANA
Core:
A E E S Y C S P K C Q T A A
Core with dehydrations:
A E E Dha Y Cys Dha P K Cys Q Dhb A A

#### antiSMASH-DB 4.0 matches for allorf_3178073_3178228

100.0%
NZ_CP096658.1:
Lanthipeptides: allorf_3178073_3178228_lanthipeptide
1
A E E S Y C S P K C Q T A A
14
A E E S Y C S P K C Q T A A
1
A E E S Y C S P K C Q T A A
14
85.7%
NZ_ML974127.1:
Lanthipeptides: allorf_1546009_1546125_lanthipeptide
2
E E S Y C S P K C Q T A A
14
+E S Y C S P K C Q T A A
1
D E S Y C S P K C Q T A A
13
28.9%
NZ_CP119804.1:
Lanthipeptides: allorf_0774884_0775030_lanthipeptide
1
A E E S Y C S P K C Q T A A
14
A E Y C S P K C Q T A
25
A E N G Y C S P K C Q T T A
38
with 24 more sequence matches
Only the first 10 are displayed here.
23.3%
NZ_CP086322.1 and 1 other:
NZ_NDXL01000003.1 Lanthipeptides: B7024_RS31125_lanthipeptide
Lanthipeptides: K9S39_RS23570_lanthipeptide
4
S Y C S P K C Q T A A
14
S C+P C T A A
5
S L C T P G C V T A A
15
21.9%
NC_014479.1 and 9 others:
NZ_CP026362.1 Lanthipeptides: BV11031_RS00400_lanthipeptide NZ_CP033052.1 Lanthipeptides: D9779_RS17315_lanthipeptide NZ_CP051464.1 Lanthipeptides: HC660_RS17030_lanthipeptide NZ_JALAKK010000002.1 Lanthipeptides: MOB09_RS02800_lanthipeptide NZ_JALAKO010000014.1 Lanthipeptides: MOB26_RS08535_lanthipeptide NZ_JALAOG010000003.1 Lanthipeptides: MOC96_RS02500_lanthipeptide NZ_JALAPG010000043.1 Lanthipeptides: MOC70_RS16815_lanthipeptide NZ_JALAQI010000009.1 Lanthipeptides: MOD13_RS06065_lanthipeptide NZ_NXEM01000027.1 Lanthipeptides: CPT06_RS15285_lanthipeptide
Lanthipeptides: BSUW23_RS16845_lanthipeptide
3
E S Y C S P K C Q T A A
14
E S C+P C T A
4
E S L C T P G C V T G A
15
20.8%
NZ_CP007699.2 and 8 others:
NZ_CP048882.1 Lanthipeptides: G4Z16_RS06545_lanthipeptide NZ_CP048882.1 Lanthipeptides: G4Z16_RS06545_lanthipeptide NZ_FMHI01000015.1 Lanthipeptides: H180DRAFT_RS21560_lanthipeptide NZ_JADDUE010000020.1 Lanthipeptides: INP57_RS28495_lanthipeptide NZ_JAMTCQ010000009.1 Lanthipeptides: LY41_RS11610_lanthipeptide NZ_KB905819.1 Lanthipeptides: F603_RS34750_lanthipeptide NZ_LIVZ01000011.1 Lanthipeptides: AMK31_RS29125_lanthipeptide NZ_LIXJ01000007.1 Lanthipeptides: AMK22_RS13160_lanthipeptide
Lanthipeptides: T261_RS08380_lanthipeptide
4
S Y C S P K C Q T
12
S Y C+P C +
5
S Y C T P G C T S
13
20.7%
NZ_CP101621.1:
Lanthipeptides: NN913_RS16125_lanthipeptide
1
A E E S Y C S P K C Q T A A
14
+S C+P C T A
2
V S K S L C T P G C I T G A
15
18.8%
NC_016047.1 and 2 others:
NZ_KZ848487.1 Lanthipeptides: DSL71_RS15965_lanthipeptide NZ_MUXL01000003.1 Lanthipeptides: B0W20_RS12275_lanthipeptide
Lanthipeptides: GYO_RS39160_lanthipeptide
3
E S Y C S P K C Q T A
13
E S C+P C T
4
E S V C T P G C V T G
14
18.8%
NZ_CP021903.1 and 20 others:
NZ_CP023409.1 Lanthipeptides: Bateq7PJ16_RS18530_lanthipeptide NZ_CP026036.1 Lanthipeptides: C2H93_RS15000_lanthipeptide NZ_CP028218.1 Lanthipeptides: C7M30_RS14555_lanthipeptide NZ_CP035167.1 Lanthipeptides: EQJ08_RS17140_lanthipeptide NZ_CP035226.1 Lanthipeptides: EQW70_RS18175_lanthipeptide NZ_CP045006.1 Lanthipeptides: F9B13_RS03875_lanthipeptide NZ_CP076083.1 Lanthipeptides: KFF76_RS16710_lanthipeptide NZ_CP079759.1 Lanthipeptides: KXZ66_RS17780_lanthipeptide NZ_CP080508.1 Lanthipeptides: K0V03_RS06525_lanthipeptide NZ_CP089148.1 Lanthipeptides: LRO88_RS19055_lanthipeptide NZ_JALAUA010000003.1 Lanthipeptides: MOD32_RS04985_lanthipeptide NZ_JALAVX010000009.1 Lanthipeptides: MOE40_RS09385_lanthipeptide NZ_JAMYDW010000007.1 Lanthipeptides: NHM07_RS16180_lanthipeptide NZ_JAQOXM010000001.1 Lanthipeptides: PO770_RS03875_lanthipeptide NZ_NJRD01000003.1 Lanthipeptides: CE053_RS07200_lanthipeptide NZ_NJRE01000008.1 Lanthipeptides: CE047_RS18435_lanthipeptide NZ_SORJ01000001.1 Lanthipeptides: BJ795_RS01490_lanthipeptide NZ_VFNF01000001.1 Lanthipeptides: FB592_RS01525_lanthipeptide NZ_VIOH01000001.1 Lanthipeptides: FLN47_RS03850_lanthipeptide NZ_VLJL01000012.1 Lanthipeptides: L604_RS09425_lanthipeptide
Lanthipeptides: CD007_RS17065_lanthipeptide
3
E S Y C S P K C Q T A A
14
E S C+P C T
4
E S L C T P G C V T G V
15
18.8%
NZ_CP025079.1 and 3 others:
NZ_CP047644.1 Lanthipeptides: GNE05_RS17275_lanthipeptide NZ_CP099859.1 Lanthipeptides: NIZ95_RS16280_lanthipeptide NZ_CP101621.1 Lanthipeptides: NN913_RS16115_lanthipeptide
Lanthipeptides: BVQ_RS17705_lanthipeptide
3
E S Y C S P K C Q T A A
14
E S C+P C T
4
E S V C T P G C V T G V
15
18.8%
NZ_CP059471.1 and 3 others:
NZ_FNZW01000001.1 Lanthipeptides: BMZ61_RS02110_lanthipeptide NZ_FOYC01000001.1 Lanthipeptides: BMZ88_RS03370_lanthipeptide NZ_KE384124.1 Lanthipeptides: G597_RS0106700_lanthipeptide
Lanthipeptides: H1R75_RS06635_lanthipeptide
2
E E S Y C S P K C Q T A A
14
+S C+P C+T A
3
S K S L C T P G C K T G A
15
18.2%
NZ_CP085954.1:
Lanthipeptides: LK411_RS13585_lanthipeptide
1
A E E S Y C S P K C Q T A A
14
+S C+P C T A
2
T S K S L C T P G C P T G A
15
17.6%
NC_013656.1 and 28 others:
NC_020450.1 Lanthipeptides: LILO_RS03015_lanthipeptide NZ_CP009472.1 Lanthipeptides: LG36_RS03420_lanthipeptide NZ_CP010050.1 Lanthipeptides: QI18_RS03300_lanthipeptide NZ_CP015903.1 Lanthipeptides: LLUC08_RS03255_lanthipeptide NZ_CP024954.1 Lanthipeptides: CV702_RS02990_lanthipeptide NZ_CP065984.1 Lanthipeptides: I6I21_RS02785_lanthipeptide NZ_CP066300.1 Lanthipeptides: LacL0098_RS03205_lanthipeptide NZ_CP090412.1 Lanthipeptides: LZF92_RS09890_lanthipeptide NZ_CP095737.1 Lanthipeptides: MXM90_RS03205_lanthipeptide NZ_CP098790.1 Lanthipeptides: M5C73_RS03405_lanthipeptide NZ_FBTD01000003.1 Lanthipeptides: PB1E_RS03075_lanthipeptide NZ_JAALEQ010000006.1 Lanthipeptides: HFD15_RS10120_lanthipeptide NZ_JAJONJ010000005.1 Lanthipeptides: LSG16_RS07195_lanthipeptide NZ_JAQDWM010000007.1 Lanthipeptides: PGU01_RS08180_lanthipeptide NZ_JAQDXJ010000021.1 Lanthipeptides: PGU19_RS11740_lanthipeptide NZ_JAQDXV010000018.1 Lanthipeptides: PGT80_RS11850_lanthipeptide NZ_JAQDYA010000007.1 Lanthipeptides: PGT72_RS09560_lanthipeptide NZ_JAQDYA010000007.1 Lanthipeptides: PGT72_RS09560_lanthipeptide NZ_JAQEIZ010000019.1 Lanthipeptides: PGX18_RS12025_lanthipeptide NZ_JAQEOU010000022.1 Lanthipeptides: PGV42_RS12330_lanthipeptide NZ_JAQEOV010000015.1 Lanthipeptides: PGW09_RS10765_lanthipeptide NZ_MTJP01000006.1 Lanthipeptides: BW151_RS03795_lanthipeptide NZ_MTJR01000005.1 Lanthipeptides: BW153_RS02980_lanthipeptide NZ_MTJS01000002.1 Lanthipeptides: BW154_RS09850_lanthipeptide NZ_QSTB01000004.1 Lanthipeptides: DXC22_RS03785_lanthipeptide NZ_RAGL01000022.1 Lanthipeptides: D6108_RS11395_lanthipeptide NZ_VSTZ01000009.1 Lanthipeptides: FYK98_RS07445_lanthipeptide NZ_VSTZ01000009.1 Lanthipeptides: FYK98_RS07445_lanthipeptide
Lanthipeptides: LLKF_RS13210_lanthipeptide
4
S Y C S P K C Q T A A
14
S C+P C+T A
5
S L C T P G C K T G A
15

#### MIBiG 4.0 matches for allorf_3178073_3178228

17.6%
BGC0000535.4 (ADJ56352.1):
Lanthipeptide: nisin A
4
S Y C S P K C Q T A A
14
S C+P C+T A
5
S L C T P G C K T G A
15
allorf_3189783_3190004
Leader:
MFDSGLGRVTVVADFEGRLGPPAKGSTRSSRPSRHRVPAA
Core:
V R S R S G R C P A A F R P G V R R L S P S R D A R R S C Q S K N
Core with dehydrations:
V R Dha R Dha G R Cys P A A F R P G V R R L Dha P Dha R D A R R Dha Cys Q Dha K N

#### antiSMASH-DB 4.0 matches for allorf_3189783_3190004

100.0%
NZ_CP096658.1:
Lanthipeptides: allorf_3189783_3190004_lanthipeptide
1
V R S R S G R C P A A F R P G V R R L S P S R D A R R S C Q S K N
33
V R S R S G R C P A A F R P G V R R L S P S R D A R R S C Q S K N
1
V R S R S G R C P A A F R P G V R R L S P S R D A R R S C Q S K N
33
32.5%
NC_016582.1 and 1 other:
NC_016582.1 Lanthipeptides: allorf_08370433_08370603_lanthipeptide
Lanthipeptides: allorf_08370433_08370603_lanthipeptide
3
S R S G R C P A A F R P G V R-R L S P S R
23
+R+G R P A F R P V R R P+R
8
N R A G R G P A-F R P A V R Q R A H P A R
28
27.9%
NZ_CP017169.1 and 1 other:
NZ_CP017172.1 Lanthipeptides: allorf_8132949_8133116_lanthipeptide
Lanthipeptides: allorf_8050142_8050309_lanthipeptide
3
S R S G R C P A A F R P G V R R L S P S R D A R R S C Q
30
S+S R P F R P R+S R R S
2
S Q S S R A P R L F R P N P A R V S S R P W G R R S V H
29
with 1 more sequence matches
24.2%
NZ_LMHM01000001.1:
Lanthipeptides: allorf_734316_734534_lanthipeptide
3
S R S G R C P A A F R P G
15
S R G R C A F G
6
S R D G R C V C A F M K G
18
allorf_3198246_3198419
Leader:
MRGRLCGPLFDAPNEARRENIPQSDREREGA
Core:
F E A V V A T I L A V S S Q S I C S L K G T A T H S
Core with dehydrations:
F E A V V A Dhb I L A V Dha Dha Q Dha I Cys Dha L K G Dhb A Dhb H Dha

#### antiSMASH-DB 4.0 matches for allorf_3198246_3198419

100.0%
NZ_CP096658.1:
Lanthipeptides: allorf_3198246_3198419_lanthipeptide
1
F E A V V A T I L A V S S Q S I C S L K G T A T H S
26
F E A V V A T I L A V S S Q S I C S L K G T A T H S
1
F E A V V A T I L A V S S Q S I C S L K G T A T H S
26
13.3%
NZ_JAGFWR010000004.1:
Lanthipeptides: allorf_403554_403718_lanthipeptide
11
V S S Q S I C S L K G T A T
24
V+S Q S+C ++ A
21
V A S Q S V C R I R R A A N
34

#### Legend:

Dha: Didehydroalanine
Dhb: Didehydrobutyrine
Lanthipeptides
Core peptide predictions
Lists the possible core peptides in the region. Each core peptide lists the number of lanthionine bridges, possible molecular weights, and the scores for cleavage site prediction and RODEO.

M0R88_RS16185 - Class II
  Cleavage pHMM score: -5.60
  RODEO score: 0
  Monoisotopic mass: 5034.1 Da
  Molecular weight: 5037.4 Da
  Number of bridges: 4
  Alternative weights
    (assuming N unmodified Ser/Thr residues)
    5055.4 Da N = 1
    5073.4 Da N = 2
allorf_3178073_3178228 - Class II
  Cleavage pHMM score: -3.20
  RODEO score: 0
  Monoisotopic mass: 1432.6 Da
  Molecular weight: 1433.6 Da
  Number of bridges: 2
  Alternative weights
    (assuming N unmodified Ser/Thr residues)
    1451.6 Da N = 1
allorf_3189783_3190004 - Class II
  Cleavage pHMM score: -4.60
  RODEO score: 0
  Monoisotopic mass: 3605.0 Da
  Molecular weight: 3607.1 Da
  Number of bridges: 2
  Alternative weights
    (assuming N unmodified Ser/Thr residues)
    3625.1 Da N = 1
    3643.1 Da N = 2
    3661.1 Da N = 3
    3679.2 Da N = 4
allorf_3198246_3198419 - Class II
  Cleavage pHMM score: -5.40
  RODEO score: 0
  Monoisotopic mass: 2475.4 Da
  Molecular weight: 2476.8 Da
  Number of bridges: 1
  Alternative weights
    (assuming N unmodified Ser/Thr residues)
    2494.8 Da N = 1
    2512.9 Da N = 2
    2530.9 Da N = 3
    2548.9 Da N = 4
    2566.9 Da N = 5
    2584.9 Da N = 6
    2603.0 Da N = 7

NZ_CP096658.1 - Region 9 - terpene-precursor
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Download region GenBank file
Download region SVG
Location: 3,200,516 - 3,221,577 nt. (total: 21,062 nt) Show pHMM detection rules used
terpene-precursor: (PT_FPPS_like and not PT_HPP)

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
TTA codons
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
Gene overview
Tailoring
MIBiG comparison
KnownClusterBlast
SubClusterBlast
Terpene
Gene/CDS overview
A brief tabular summary of genes/CDS features within the region.
Filtering the table will also search biosynthetic profiles and gene function data. If enabled, the overview will then zoom to show the area covered by the filtered selection.
Genes selected in the region drawing above will be marked in the table with an indicator to the left of the gene name.
Filter:
Automatically zoom to filtered/selected features

Identifier | Product | Length | Function | Sequence | NCBI Blast | Filter details
--- | --- | --- | --- | --- | --- | ---
|  | NT | AA |  | NT | AA |  |

No genes match the given filter
Tailoring functions
Tailoring enzymes detected in this region
Oxidoreductases: oxidoreductase
M0R88_RS16310: oxidoreductase

smcogs
  SMCOG1083: oxidoreductase

Transferases: aminotransferase
M0R88_RS16290: aminotransferase

smcogs
  SMCOG1019: aminotransferase

Ligases: synthetase
M0R88_RS16330: Polyprenyl synthetase

smcogs
  SMCOG1182: Polyprenyl synthetase

Similar gene clusters
Shows areas that are similar to the current region to a reference database.
Mouseover a score cell in the table to get a breakdown of how the score was calculated.The MIBiG database.
Click on an accession to open that entry in the MIBiG database.
Analysis type:

Reference | terpene-precursor | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0000677.5 |  | 0.41 | terpene | cyclooctatin | Streptomyces melanosporofaciens
BGC0000639.3 |  | 0.37 | terpene | carotenoid | Enterobacteriaceae bacterium DC260
BGC0001911.3 |  | 0.37 | terpene | raimonol | Streptomyces anulatus
BGC0001485.4 |  | 0.37 | other (other) | chuangxinmycin | Actinoplanes tsinanensis
BGC0000642.3 |  | 0.37 | terpene | carotenoid | Enterobacteriaceae bacterium DC413
BGC0002309.2 |  | 0.36 | terpene | cattleyene | Streptomyces cattleya NRRL 8057 = DSM 46488
BGC0001972.4 |  | 0.36 | other (other) | toxoflavin, fervenulin | Streptomyces hiroshimensis
BGC0001910.4 |  | 0.35 | terpene | cyslabdan A, cyslabdan B, cyslabdan C | Streptomyces cyslabdanicus
BGC0000648.3 |  | 0.34 | terpene | carotenoid | Myxococcus xanthus
BGC0000644.3 |  | 0.34 | terpene | carotenoid | Dietzia sp. CQ4

Reference | Aggregated | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0000677.5 |  | 0.41 | terpene | cyclooctatin | Streptomyces melanosporofaciens
BGC0000639.3 |  | 0.37 | terpene | carotenoid | Enterobacteriaceae bacterium DC260
BGC0001911.3 |  | 0.37 | terpene | raimonol | Streptomyces anulatus
BGC0001485.4 |  | 0.37 | other (other) | chuangxinmycin | Actinoplanes tsinanensis
BGC0000642.3 |  | 0.37 | terpene | carotenoid | Enterobacteriaceae bacterium DC413
BGC0002309.2 |  | 0.36 | terpene | cattleyene | Streptomyces cattleya NRRL 8057 = DSM 46488
BGC0001972.4 |  | 0.36 | other (other) | toxoflavin, fervenulin | Streptomyces hiroshimensis
BGC0001910.4 |  | 0.35 | terpene | cyslabdan A, cyslabdan B, cyslabdan C | Streptomyces cyslabdanicus
BGC0000648.3 |  | 0.34 | terpene | carotenoid | Myxococcus xanthus
BGC0000644.3 |  | 0.34 | terpene | carotenoid | Dietzia sp. CQ4

Similar known clusters from MIBiG 4.0
Shows clusters from the MIBiG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Detailed help and explanations are available here.
Click on reference genes to show details of similarities to genes within the current region.
Double click on a reference drawing to reverse the display of the genes.
Click on an accession to open that entry in the MIBiG database.

No significant matches found.

Similar subclusters
Shows sub-cluster units that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Detailed help and explanations are available here.
Click on reference genes to show details of similarities to genes within the current region.
Double click on a reference drawing to reverse the display of the genes.

No significant matches found.

Detailed terpene predictions
Detailed information for terpene domains. Shows possible products of a terpene cluster and lists the subtype and expected reactions for each terpene-related domain.
Product predictions:

Class | Subclass | Product name | Chain length | Initial cyclisations | Functional groups
--- | --- | --- | --- | --- | ---
sesquiterpene precursor |  | FPP | C15 | acyclic | PP
diterpene precursor |  | GGPP | C20 | acyclic | PP
sesterterpene precursor |  | GFPP | C25 | acyclic | PP
triterpene precursor |  | HPP | C30 | acyclic | PP

Genes with terpene domains:
M0R88_RS16330: PT_FPPS_like
Domain 1 (40 - 351): Prenyltransferase; Farnesyl diphosphate synthase like
Subtype: unknown

Reactions:
  IPP, DMAPP → FPP
  IPP, DMAPP → GGPP
  IPP, DMAPP → GFPP
  IPP, DMAPP → HPP

Terpene
Glossary
Glossary showing acronyms and their full names.

Acronym | Full name
--- | ---
DMAPP | Dimethylallyl diphosphate
FPP | Farnesyl diphosphate
GFPP | Geranylfarnesyl diphosphate
GGPP | Geranylgeranyl diphosphate
HPP | Hexaprenyl diphosphate
IPP | Isopentenyl diphosphate
PP | Diphosphate

NZ_CP096658.1 - Region 10 - terpene
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Download region GenBank file
Download region SVG
Location: 3,295,237 - 3,316,322 nt. (total: 21,086 nt) Show pHMM detection rules used
terpene: (PT_phytoene_like or phytoene_synt or Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or T2TS or TS_UbiA or TS_Pyr4)

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
TTA codons
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
Gene overview
Tailoring
MIBiG comparison
KnownClusterBlast
SubClusterBlast
Terpene
Gene/CDS overview
A brief tabular summary of genes/CDS features within the region.
Filtering the table will also search biosynthetic profiles and gene function data. If enabled, the overview will then zoom to show the area covered by the filtered selection.
Genes selected in the region drawing above will be marked in the table with an indicator to the left of the gene name.
Filter:
Automatically zoom to filtered/selected features

Identifier | Product | Length | Function | Sequence | NCBI Blast | Filter details
--- | --- | --- | --- | --- | --- | ---
|  | NT | AA |  | NT | AA |  |

No genes match the given filter
Tailoring functions
Tailoring enzymes detected in this region
Oxidoreductases: dehydrogenase oxidoreductase
M0R88_RS16825: acyl-CoA dehydrogenase

smcogs
  SMCOG1006: acyl-CoA dehydrogenase

M0R88_RS16855: 3-hydroxybutyryl-CoA dehydrogenase

smcogs
  SMCOG1095: 3-hydroxybutyryl-CoA dehydrogenase

M0R88_RS16895: oxidoreductase

smcogs
  SMCOG1079: oxidoreductase

Similar gene clusters
Shows areas that are similar to the current region to a reference database.
Mouseover a score cell in the table to get a breakdown of how the score was calculated.The MIBiG database.
Click on an accession to open that entry in the MIBiG database.
Analysis type:

Reference | terpene | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0000706.3 |  | 0.45 | saccharide | kanamycin | Streptomyces kanamyceticus
BGC0002284.3 |  | 0.43 | other (other) | corynecin III, corynecin I, corynecin II | Rhodococcus sp. H-CA8f
BGC0000278.3 |  | 0.42 | PKS | urdamycin | Streptomyces fradiae
BGC0000207.5 |  | 0.39 | PKS | chartreusin | Streptomyces chartreusis
BGC0000719.5 |  | 0.38 | saccharide | tobramycin | Streptoalloteichus hindustanus
BGC0000720.3 |  | 0.36 | saccharide | tobramycin | Streptoalloteichus tenebrarius
BGC0001464.3 |  | 0.35 | other (other) | tetrabromopyrrole | Pseudoalteromonas sp. PS5
BGC0001463.4 |  | 0.35 | other (other) | 2,3,4,5-tetrabromopyrrole | Pseudoalteromonas piscicida
BGC0002091.3 |  | 0.34 | NRPS | holomycin | Yersinia ruckeri ATCC 29473
BGC0002147.2 |  | 0.33 | NRPS | bohemamine A, bohemamine B, bohemamine C | Streptomyces sp. CB02009

Reference | Aggregated | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0000706.3 |  | 0.45 | saccharide | kanamycin | Streptomyces kanamyceticus
BGC0002284.3 |  | 0.43 | other (other) | corynecin III, corynecin I, corynecin II | Rhodococcus sp. H-CA8f
BGC0000278.3 |  | 0.42 | PKS | urdamycin | Streptomyces fradiae
BGC0000207.5 |  | 0.39 | PKS | chartreusin | Streptomyces chartreusis
BGC0000719.5 |  | 0.38 | saccharide | tobramycin | Streptoalloteichus hindustanus
BGC0000720.3 |  | 0.36 | saccharide | tobramycin | Streptoalloteichus tenebrarius
BGC0001464.3 |  | 0.35 | other (other) | tetrabromopyrrole | Pseudoalteromonas sp. PS5
BGC0001463.4 |  | 0.35 | other (other) | 2,3,4,5-tetrabromopyrrole | Pseudoalteromonas piscicida
BGC0002091.3 |  | 0.34 | NRPS | holomycin | Yersinia ruckeri ATCC 29473
BGC0002147.2 |  | 0.33 | NRPS | bohemamine A, bohemamine B, bohemamine C | Streptomyces sp. CB02009

Similar known clusters from MIBiG 4.0
Shows clusters from the MIBiG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Detailed help and explanations are available here.
Click on reference genes to show details of similarities to genes within the current region.
Double click on a reference drawing to reverse the display of the genes.
Click on an accession to open that entry in the MIBiG database.

No significant matches found.

Similar subclusters
Shows sub-cluster units that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Detailed help and explanations are available here.
Click on reference genes to show details of similarities to genes within the current region.
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No significant matches found.

Detailed terpene predictions
Detailed information for terpene domains. Shows possible products of a terpene cluster and lists the subtype and expected reactions for each terpene-related domain.
Product predictions:

Class | Subclass | Product name | Chain length | Initial cyclisations | Functional groups
--- | --- | --- | --- | --- | ---
triterpene |  | squalene | C30 | acyclic | none
triterpene | C30 carotenoid | diapophytoene | C30 | acyclic | none
triterpene |  | PSPP | C30 | acyclic | PP
tetraterpene | C40 carotenoid | phytoene | C40 | acyclic | none
triterpene |  | hydroxysqualene | C30 | acyclic | OH

Genes with terpene domains:
M0R88_RS16845: PT_phytoene_like
Domain 1 (26 - 293): Prenyltransferase; Phytoene synthase like
Subtype: unknown

Reactions:
  FPP → squalene
  FPP → diapophytoene
  FPP → PSPP
  GGPP → phytoene
  PSPP → hydroxysqualene

Terpene
Glossary
Glossary showing acronyms and their full names.

Acronym | Full name
--- | ---
FPP | Farnesyl diphosphate
GGPP | Geranylgeranyl diphosphate
PP | Diphosphate
PSPP | Presqualene diphosphate