LOCUS       NZ_CP096281            21056 bp    DNA     linear   CON 08-JUN-2024
DEFINITION  Streptomyces sp. WAC00303 chromosome.
ACCESSION   NZ_CP096281
VERSION     NZ_CP096281.1
KEYWORDS    RefSeq.
SOURCE      Streptomyces sp. WAC00303
  ORGANISM  Streptomyces sp. WAC00303
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1  (bases 1 to 8548838)
  AUTHORS   Meyer,K.J., Tan,S. and Nodwell,J.R.
  TITLE     Genome Sequence of WAC00303 Direct Submission
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 8548838)
  AUTHORS   Meyer,K.J., Tan,S. and Nodwell,J.R.
  TITLE     Direct Submission
  JOURNAL   Submitted (19-APR-2022) Biochemistry, University of Toronto, 1 Kings
            College Circle 5207, Toronto, ON M5S 1A8, Canada
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: 15-MAR-2022
            Assembly Method                   :: Flye v. 2.8.1
            Assembly Name                     :: WAC00303
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 58.0x
            Sequencing Technology :: Oxford Nanopore; Illumina NextSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_023210535.1-RS_2024_06_08
            Annotation Date                   :: 06/08/2024 05:21:48
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 7,823
            CDSs (total)                      :: 7,731
            Genes (coding)                    :: 7,293
            CDSs (with protein)               :: 7,293
            Genes (RNA)                       :: 92
            rRNAs                             :: 6, 6, 6 (5S, 16S, 23S)
            complete rRNAs                    :: 6, 6, 6 (5S, 16S, 23S)
            tRNAs                             :: 71
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 438
            CDSs (without protein)            :: 438
            Pseudo Genes (ambiguous residues) :: 0 of 438
            Pseudo Genes (frameshifted)       :: 228 of 438
            Pseudo Genes (incomplete)         :: 241 of 438
            Pseudo Genes (internal stop)      :: 26 of 438
            Pseudo Genes (multiple problems)  :: 54 of 438
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 18:23:54
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 8378902
            Orig. end                         :: 8399958
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP096281.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            Bacteria and source DNA available from Justin Nodwell, University
            of Toronto.
FEATURES             Location/Qualifiers
     region          1..21056
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene-precursor"
                     /region_number="36"
                     /rules="(PT_FPPS_like and not PT_HPP)"
                     /tool="antismash"
     cand_cluster    1..21056
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_FPPS_like and not PT_HPP)"
                     /kind="single"
                     /product="terpene-precursor"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..21056
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:11056](-)"
                     /cutoff="10000"
                     /detection_rule="(PT_FPPS_like and not PT_HPP)"
                     /neighbourhood="10000"
                     /product="terpene-precursor"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..11056)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="(PT_FPPS_like and not PT_HPP)"
                     /neighbourhood="10000"
                     /product="terpene-precursor"
                     /protocluster_number="1"
     misc_feature    889..902
                     /note="TFBS match to ArgR, Regulator of arginine
                     biosynthesis genes, confidence: weak, score: 16.81"
                     /tool="antismash"
     gene            complement(1022..1948)
                     /locus_tag="MWG59_RS38315"
                     /old_locus_tag="MWG59_38315"
     CDS             complement(1022..1948)
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1014: LysR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003971246.1"
                     /locus_tag="MWG59_RS38315"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MWG59_38315"
                     /product="LysR family transcriptional regulator"
                     /protein_id="WP_248587049.1"
                     /transl_table=11
                     /translation="MDIEAVRTFVTVADTGQFQEAAVELRISQQAVSKRVAGLERVLGV
                     TLFVRTARGAHPTPDGQAFLPHAREVLRAVERAASSVRPGDRVLRVDVLHRRIAPALAV
                     RGFYQAHPGTDLDVVTLADTNVTGAAEAVRAGEIDATFRAVPVGALPDGISAERVLDDP
                     LHLLVGPRHPLASARSLAPADLAGHRIWIPGIKQGTEWAAYYDRLAEDFGLRIDAVGPD
                     FGTEALMDSIADSAALATLVGSRDRYLWPAAHDLRRIPVVGPTPVYPHVFLYRTGNPHP
                     VLAALRRYLVQVRPKSPADAWTPAWAR"
     gene            2056..2670
                     /locus_tag="MWG59_RS38320"
                     /old_locus_tag="MWG59_38320"
     CDS             2056..2670
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1148: hypothetical
                     protein"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020126639.1"
                     /locus_tag="MWG59_RS38320"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MWG59_38320"
                     /product="XRE family transcriptional regulator"
                     /protein_id="WP_097933862.1"
                     /transl_table=11
                     /translation="MTQEDGELDSLVRKRIRALRVAQGWSLEELAGRAKVSQSTLSRIE
                     NGRRRLALDQLVTLARALDTSLDQLVETASDDIVSNPMIDGAHGQMRWPIKAEPGMTVI
                     RQRMTEPPPDNPSRLRAHPGREWLVVLSGTAILLLGNRRLRIETNQAAEFPTMLPHAIG
                     AEGGPCELLGIFDRDARRGHQRGEGAEQANRPTPPPGRSLP"
     assembly_gap    2757..2766
                     /estimated_length=10
                     /gap_type="within scaffold"
                     /linkage_evidence="paired-ends"
     gene            complement(2821..3957)
                     /locus_tag="MWG59_RS38325"
                     /old_locus_tag="MWG59_38325"
     CDS             complement(2821..3957)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018893396.1"
                     /locus_tag="MWG59_RS38325"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MWG59_38325"
                     /product="PQQ-dependent sugar dehydrogenase"
                     /protein_id="WP_248587050.1"
                     /transl_table=11
                     /translation="MKFRTRSSAIIGTLCLVTSLTLATASAVEPADPVKPVSASLTEVA
                     RAQGPSGGAAGPDDTLWIAERAGTVRVLDDQGLGAPVLDISDETTTDGERGLLGVAFDK
                     TFAHFYISFTDLEGTSTVDEFAVEGGRLQPDSRRTVLTQTQPYANHNGGDIKFGPDGYL
                     YIAFGDGGSGGDPHGNGQKLDTLLGKLLRIDPTGGEPYAIPADNPFVDDANAKDEIWSY
                     GLRNPWRFSFDAGTGDLLIGDVGQSDWEEIDWAPADSKGGENYGWASMEGTHPFRGGTE
                     PANHVPPVHEYDRTGLGCSVTGGFVYRGDALPDLRGSYVFSDYCDGTLRTLQMKDGEVT
                     GVGDLGVSGGEVISFVEGGDGELYVLGSGGVVSRVDPA"
     misc_feature    complement(4100..4115)
                     /note="TFBS match to DasR, N-acetylglucosamine dependent
                     repressor, confidence: weak, score: 21.0"
                     /tool="antismash"
     misc_feature    complement(4229..4243)
                     /note="TFBS match to CelR, Cellobiose uptake repressor,
                     confidence: medium, score: 26.66"
                     /tool="antismash"
     misc_feature    4230..4244
                     /note="TFBS match to CelR, Cellobiose uptake repressor,
                     confidence: medium, score: 25.19"
                     /tool="antismash"
     misc_feature    complement(4316..4330)
                     /note="TFBS match to CelR, Cellobiose uptake repressor,
                     confidence: strong, score: 28.15"
                     /tool="antismash"
     misc_feature    4317..4331
                     /note="TFBS match to CelR, Cellobiose uptake repressor,
                     confidence: strong, score: 28.65"
                     /tool="antismash"
     gene            4437..6566
                     /locus_tag="MWG59_RS38330"
                     /old_locus_tag="MWG59_38330"
     CDS             4437..6566
                     /GO_function="GO:0004553 - hydrolase activity, hydrolyzing
                     O-glycosyl compounds [Evidence IEA]"
                     /GO_process="GO:0030245 - cellulose catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018522812.1"
                     /locus_tag="MWG59_RS38330"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MWG59_38330"
                     /product="glycoside hydrolase family 6 protein"
                     /protein_id="WP_179889792.1"
                     /transl_table=11
                     /translation="MRSRGVTPHAPHAFRRRAAAALSALIMGAALAVAVPGQASAAARV
                     DNPYAGATAYVNPDWSARAAAEPGGEVIADEPSFVWMDRIAAIGGTPGARGLRAHLDTA
                     VSQGADLFQVVIYNLPGRDCAALASNGELGPTELSRYKDDYIDPIAGILGDPAYASLRI
                     VTLIEPDSLPNLVTNAGGTAGSTPECATMKANGNYEKGIGYALHTLGALPNVYNYVDAA
                     HHGWLGWDSNFVPAAQQFKKAATTEGATVSDVHGFIVNTANYSALEEPHFAVTDSVNGT
                     TVRQSRWVDWNYYVDELSFAKALRTELVRQGFASDIGMLIDTARNGWGGSARPTGPGPL
                     TSADAYVDGGRTDRRIHAGNWCNQSGAGIGERPTTAPEPGIDAYVWAKPPGESDGSSEP
                     VDNDEGKGFDRMCDPTYTGNGRNGFNLTGALPDSPVAGHWFSGQFQELLRNAHPPLDGG
                     SGGEEDTQAPTVPTSLRVTAKSSSSVTLAWAASTDDTGVTGYDILRDGAPVGTTAATTY
                     TDTGVSASTAYSYSVRAKDAAGNVSAGAPAAQVTTEAGGGTGTGALKAEYRNTDGSPTD
                     NQIRMSLRLVNTGSAAIDLSTVTARYWFTPDGGASTFGTACDYAVLGCGNVTHGVRSAS
                     APATGASHYLEVGFGSGSLAAGATTGEIQLRLNKSDWSAFQESDDYSRSTNTAFADAPR
                     VGVFTGSTLAWGTAP"
     gene            complement(6669..8597)
                     /locus_tag="MWG59_RS38335"
                     /old_locus_tag="MWG59_38335"
     CDS             complement(6669..8597)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003971250.1"
                     /locus_tag="MWG59_RS38335"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MWG59_38335"
                     /product="HtaA domain-containing protein"
                     /protein_id="WP_248587051.1"
                     /transl_table=11
                     /translation="MSMPRRGRLAALAALTVVSVGAGVLAVPASAAPGVHAAARAEAGG
                     TTSAAAPILVTGRSSWGFKDSWVRYVTGMGGSVNVAGGAGADAAGRVDYPVKHGSVDPA
                     ERSADVRFGGSVTYAVPSHGITAITLANPRVVLKDGKGTLHMDVTTDIAAGQAPVTTPG
                     VPLAALTASADALDGAVLDWTGITATLTEEGSAIFAYQGRPMYPAGTALDPVAISGGVS
                     VPTLTVSQVSELGAENEVTVSGKGYQPGRGVYLAQSIALPGTTYPSVFGNAAYIRQVGA
                     DGTFSVTLKLTETFTPSGAPVVDCRTTACFVTSFNSHDGGDPTWMPSRAQDVAQPLRFG
                     VEVPAATVTQHPASRTVRSGATGTFTAAATGADSVRWERSTDRGTTWSTVPGATTATLP
                     VKAAAALDGHRYRAVFVNASGETATSAATLTVSAVPTRIVSFNASPEPVGKGSKLKVVA
                     TLQTASATDNVWRPLAKTPVVIEFRSKGGKTWSRTTTVTANSKGVVSASVTAVKDGTWR
                     ARYAGTADRAAAVSSSDNVDVKLRTAVSGFNASPEPVRKGRTITVKGTLRSLDGTWKNA
                     SGQSVIVLFKADGSSKWSKLATVRTNGKGVFSKGFTAKKDGTWKAQFKATSSRLGTIGS
                     GDRVDVH"
     misc_feature    8587..8600
                     /note="TFBS match to ArgR, Regulator of arginine
                     biosynthesis genes, confidence: weak, score: 16.85"
                     /tool="antismash"
     misc_feature    8727..8745
                     /note="TFBS match to DmdR1, Iron(II)-dependent repressor,
                     confidence: medium, score: 31.03"
                     /tool="antismash"
     gene            complement(8749..9924)
                     /locus_tag="MWG59_RS38340"
                     /old_locus_tag="MWG59_38340"
     CDS             complement(8749..9924)
                     /EC_number="1.-.-.-"
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014152514.1"
                     /locus_tag="MWG59_RS38340"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MWG59_38340"
                     /product="oxygenase MpaB family protein"
                     /protein_id="WP_248587052.1"
                     /transl_table=11
                     /translation="MTYTEASMNALRQGGDELADATVAALFDRGEVGKFNTLMRYVSTA
                     GAPLPDGLPDVARDYLQATSAPPDWVDWEEMEKARLFFIDNNVHISTALSFASMPACYV
                     VPHVAKLLSATHGLKYPSKRMAETGQFTVYLMRPDAFEAGGRFVPAAQKVRLLHASIRH
                     HLLREKRWDTDALGTPICQEDMIGGQMFFSLLVLDSLHRLGIHMSEEGAAAYYYAWRVV
                     GAMLGVSQESVPRSLDEARQFLDLYMIRHMGPSEEGALLTRQLIDLYEEVVPGTFFDPI
                     VSALIRHLVGDTCADWLQVPRTSWDTAVKAVPHLLGILETVEDRSPLGAWALDRLGHLT
                     TVLELSSLTRGRVMHYAIPEQLKEEYGVSAGASRSRWKPPSVTVSGRTPPW"
     gene            complement(10001..11056)
                     /locus_tag="MWG59_RS38345"
                     /old_locus_tag="MWG59_38345"
     CDS             complement(10001..11056)
                     /GO_process="GO:0008299 - isoprenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene-precursor: PT_FPPS_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1182: Polyprenyl synthetase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018956355.1"
                     /locus_tag="MWG59_RS38345"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MWG59_38345"
                     /product="polyprenyl synthetase family protein"
                     /protein_id="WP_248587053.1"
                     /sec_met_domain="PT_FPPS_like (E-value: 9.6e-33, bitscore:
                     112.3, seeds: 145, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTPDRWDTAAFKARVDEVLHPFVAREADLFAAIDPSLAPVAAQVE
                     EAVADGKRLRAAFCYWGWRAAGQPDSAALVRAAASLELIHAAAVVHDDLIDDSALRHGR
                     PTAHIALRGAVRRRPRSVAAARSLAMLVGDLLMGMAGQLFTTSGLPAVYLGRARPLWTV
                     LGRELIAGECLEILRTGAEPDTGASLKVIRYKTAKYTVEQPLLIGGALAGAGGRLREGY
                     SAYGLPLGEAFQLRDDLLGLFGDPGRTGKANADDVCGHRPTALLAETWRVAGDDDRDRL
                     RALLGRRDLDEDGLDAVRDVMRRLKTPGLVEDMITARVEEALDALHELDVPSRAADALA
                     ALANSATVRLS"
     gene            complement(11046..11324)
                     /locus_tag="MWG59_RS38350"
                     /old_locus_tag="MWG59_38350"
     CDS             complement(11046..11324)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003971253.1"
                     /locus_tag="MWG59_RS38350"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MWG59_38350"
                     /product="polyprenyl synthetase"
                     /protein_id="WP_097933879.1"
                     /transl_table=11
                     /translation="MTREAGRDGDLDERVVLLVAGAADMAVSAVGSALGAVRGLLRRSD
                     AAELAAQAEHELTARGRLVLDRYAAPPPAHLELLARHVVARRASDDA"
     misc_feature    11359..11374
                     /note="TFBS match to AfsQ1, Two-component system AfsQ1-Q2,
                     activator of antibiotic production, confidence: medium,
                     score: 17.11"
                     /tool="antismash"
     gene            complement(11527..12672)
                     /locus_tag="MWG59_RS38355"
                     /old_locus_tag="MWG59_38355"
     CDS             complement(11527..12672)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018956352.1"
                     /locus_tag="MWG59_RS38355"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MWG59_38355"
                     /product="DUF6596 domain-containing protein"
                     /protein_id="WP_097933854.1"
                     /transl_table=11
                     /translation="MNEVLLRSLTPSVLGILVRRGADFAAAEDAVQDALVEAVRVWPDE
                     QPRDPKGWLVTVAWRRFLDATRAEAARRRREDLVDEEPAPGPVPAADDTLQLYFLCAHP
                     SLTPSSAVALTLRAVGGLTTRQIARAYLVPEATMAQRISRAKRTVSGVPFDQPGDVATV
                     LRVLYLVFNEGYSGDVDLAAEAIRLTRQLAAAIDHPEVAGLLALMMLHHARRATRTAPD
                     GSLVPLAEQDRGRWDTGAITEGVGILQAALARDRLGEFQAQAAIAALHADAPTAEETDW
                     VQIVEWYDELVGLTDSPVVRLNRAVAVGEADGPRAGLAELAALSDTLPRHTAVAAYLHE
                     RDGDLPTAARLYAEAAHKAPTLAERDHLTRRAARLNAGLRR"
     gene            complement(12680..13087)
                     /locus_tag="MWG59_RS38360"
                     /old_locus_tag="MWG59_38360"
     CDS             complement(12680..13087)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003935476.1"
                     /locus_tag="MWG59_RS38360"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MWG59_38360"
                     /product="YciI family protein"
                     /protein_id="WP_050363040.1"
                     /transl_table=11
                     /translation="MAKYLLLKHYRGAPAAVNDVPMDRWTPEEISAHMQYMQDFADRLE
                     KTGEFVEGSALAPEGAWVRYDGEGRPPVTDGPFAETKDLIAGWMIIDVDGYDRAVELAG
                     ELSAAPGAGGKPIHEWLEVRPFLSAPPTVTE"
     misc_feature    complement(13121..13130)
                     /note="TFBS match to AbrC3, Antibiotic production
                     activator, confidence: strong, score: 18.16"
                     /tool="antismash"
     misc_feature    13180..13195
                     /note="TFBS match to ColR, Phenol-responsive regulator,
                     confidence: weak, score: 17.87"
                     /tool="antismash"
     gene            complement(13219..14427)
                     /locus_tag="MWG59_RS38365"
                     /old_locus_tag="MWG59_38365"
     CDS             complement(13219..14427)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019057045.1"
                     /locus_tag="MWG59_RS38365"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MWG59_38365"
                     /product="saccharopine dehydrogenase C-terminal
                     domain-containing protein"
                     /protein_id="WP_248587054.1"
                     /transl_table=11
                     /translation="MRVLLVGAGGVGTAITRIAARRSFFDHMVVTDYDLSRAEAAVAAL
                     GGEETRFTALRIDASDRAAVTALLTEQRCDILVNATDPRFVMPLFEAALAAGVDYLDMA
                     MSLSLPHPERPYEQCGVKLGDRQFERAAAWEEAGRLALVGVGVEPGLSDVFARYAADEL
                     FDEIEEIGVRDGANLTVEGYDFAPSFSIWTTIEECLNPPVVWERDRGWFTTAPFSEPEV
                     FDFPEGIGPVACVNVEHEEVLLIPRWVESRRVTFKYGLGDEFIETLKTLHSLGLDRTDK
                     VTVPGGEVSPRDVVAACLPDPASLGELMRGKTCAGTRVTGTKDGAPRDVYLYHVVDNQW
                     SMREYGSQAVVWQTAINPVIALELVASGVWSGAGVLGAEALAPRPFLDLLVAYGSPWGL
                     REQ"
     misc_feature    complement(14504..14517)
                     /note="TFBS match to ANR, Anaerobic transcriptional
                     regulator, confidence: weak, score: 19.21"
                     /tool="antismash"
     gene            14673..15479
                     /locus_tag="MWG59_RS38370"
                     /old_locus_tag="MWG59_38370"
     CDS             14673..15479
                     /GO_function="GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /NRPS_PKS="Domain: Abhydrolase_1 (21-141). E-value:
                     1.2e-14. Score: 46.5. Matches aSDomain:
                     nrpspksdomains_MWG59_RS38370_Abhydrolase_1.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF00561"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Abhydrolase_6"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1036: alpha/beta hydrolase fold protein"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007459126.1"
                     /locus_tag="MWG59_RS38370"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MWG59_38370"
                     /product="alpha/beta hydrolase"
                     /protein_id="WP_248587055.1"
                     /sec_met_domain="PF00561 (E-value: 5.6e-09, bitscore: 34.8,
                     seeds: 48, tool: rule-based-clusters)"
                     /sec_met_domain="Abhydrolase_6 (E-value: 1.7e-23, bitscore:
                     83.2, seeds: 455, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MGEYADLPGVRTWYETEGTGDPLVLLHGGFCTNDTWGAQRADLAS
                     TYRVYLPERRAHGHTADVAGPLTYQDMADDTVAFLEEVVGGPAHLVGWSDGGVVALIVA
                     GDRPDLVRKAVAIGANFRPGPECFVEPSMLDAMTPSGPDLAFFRELYEPVSPDGAGHWP
                     VVAEKVIDMWRTQPALTAEDLARVGAPTLVMAGDDDLMTLEHTTALYRAIPDAELAVVP
                     GASHLVPLEKPTLVNRLILDHLAQEAVETMMPIRRAETGAPEGAEI"
     aSDomain        14736..15095
                     /aSDomain="Abhydrolase_1"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_MWG59_RS38370_Abhydrolase_1.1"
                     /evalue="1.20E-14"
                     /label="MWG59_RS38370_Abhydrolase_1.1"
                     /locus_tag="MWG59_RS38370"
                     /protein_end="141"
                     /protein_start="21"
                     /score="46.5"
                     /tool="antismash"
                     /translation="PLVLLHGGFCTNDTWGAQRADLASTYRVYLPERRAHGHTADVAGP
                     LTYQDMADDTVAFLEEVVGGPAHLVGWSDGGVVALIVAGDRPDLVRKAVAIGANFRPGP
                     ECFVEPSMLDAMTPSG"
     CDS_motif       14928..14984
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_MWG59_RS38370_0001"
                     /evalue="9.20E-06"
                     /label="NRPS-te1"
                     /locus_tag="MWG59_RS38370"
                     /protein_end="104"
                     /protein_start="85"
                     /score="18.2"
                     /tool="antismash"
                     /translation="GPAHLVGWSDGGVVALIVA"
     gene            complement(15506..15997)
                     /locus_tag="MWG59_RS38375"
                     /old_locus_tag="MWG59_38375"
     CDS             complement(15506..15997)
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1284:
                     transcriptional regulator, MarR family"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003971261.1"
                     /locus_tag="MWG59_RS38375"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MWG59_38375"
                     /product="MarR family winged helix-turn-helix
                     transcriptional regulator"
                     /protein_id="WP_007459124.1"
                     /transl_table=11
                     /translation="MPAQDRAAQPSAGPSTSPGDPDQRLGFLLAYHGNATQTLIHKALA
                     ATGLTPRHMMTLLQLADGPVTQKALIERLDVDPSVLVALLNDLEGDDLVRRRRDTADRR
                     RHIVEITPRGASQLRTSDTALDTVEHELFADLSERDLATLRRLLGKLRTSPQDFSCTEE
                     "
     misc_feature    complement(16032..16041)
                     /note="TFBS match to ToxT, Regulator of MSHA biosynthesis,
                     confidence: weak, score: 13.59"
                     /tool="antismash"
     misc_feature    16033..16047
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: weak, score: 18.41"
                     /tool="antismash"
     misc_feature    16041..16056
                     /note="TFBS match to CopR, Copper-responsive regulator,
                     confidence: weak, score: 19.47"
                     /tool="antismash"
     gene            16096..16443
                     /locus_tag="MWG59_RS38380"
                     /old_locus_tag="MWG59_38380"
     CDS             16096..16443
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017240258.1"
                     /locus_tag="MWG59_RS38380"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MWG59_38380"
                     /product="DoxX family protein"
                     /protein_id="WP_248587056.1"
                     /transl_table=11
                     /translation="MFIAYAVVGVLLALALGASAVLTFTRNEAITASMGKVGVPGTWFP
                     WLASLKAAGALGLLIGLGVPLIGSAAAIGVVLYFIGAVVTHLRVKDYEIAPPVVLALLA
                     AAALVLRVLSA"
     gene            16578..17162
                     /locus_tag="MWG59_RS38385"
                     /old_locus_tag="MWG59_38385"
     CDS             16578..17162
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003971263.1"
                     /locus_tag="MWG59_RS38385"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MWG59_38385"
                     /product="DUF998 domain-containing protein"
                     /protein_id="WP_098013790.1"
                     /transl_table=11
                     /translation="MRSAPWWALVSSGCAPVLLTGSWMIAQLRQGPAYDPERQTLSVLA
                     SYGAASYWLMTGMLLVLGTCYVVTAHALRPAAPAGRVALACGGLCALALTLVPAPSSGG
                     ALEHGAVSTVGLVLLAVWPPLAAVRDRKPVPWGLRLDVSLAASALMCASALWFLAELQS
                     ARAPGVAERVVTFVQALWPFLVVVSCRRSAA"
     gene            complement(17199..17747)
                     /locus_tag="MWG59_RS38390"
                     /old_locus_tag="MWG59_38390"
     CDS             complement(17199..17747)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006604220.1"
                     /locus_tag="MWG59_RS38390"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MWG59_38390"
                     /product="HAD domain-containing protein"
                     /protein_id="WP_248587057.1"
                     /transl_table=11
                     /translation="MTRTAQRPLLFLDVDGPLIPFGATSRPHPTYEMGPGTPATGANPL
                     LTRVNPQHGPRLAALPCELVWATTWMEDANAWIAPRIGLPPLPVVHWPEPSDADGADGR
                     EDQDERDGLHWKTRALVARAAGRPFVWVDDEITDTDRAWVAVHHPGPALLHRVDPRRGL
                     ADCDYTAVGAWLRGVAGDV"
     gene            complement(17888..20884)
                     /locus_tag="MWG59_RS38395"
                     /old_locus_tag="MWG59_38395"
     CDS             complement(17888..20884)
                     /GO_function="GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003946669.1"
                     /locus_tag="MWG59_RS38395"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MWG59_38395"
                     /product="family 16 glycoside hydrolase"
                     /protein_id="WP_248587058.1"
                     /transl_table=11
                     /translation="MHPRPLHRCRRHLTGLLVSAFLVGALSAVPAAAAPVPLDELPPQE
                     PGVTLRVFDVQVPLSELCDIKAGQTPNVDKLMPAIDWSSADDFGFGDHFVSQATANLTV
                     PEGGAYAFRLTSDDGSRLRIDGSTVIDHDGLHGAEPKDGTVNLTAGHHPLRIDHFDRTG
                     GQQVTLEWKPPGAGDFAVVPTSVLSTDADVVRVTAPGRKECEGVLDSPGDGLPLAGTHP
                     DYALTDLRPAGFEPQVTAMDWLPDGRLAVTTWGGTDNTTGEVYLLDNVQGDTGPGEVTA
                     KKVAEGLKEPMGIKAVDGKLYVSQKHELTELTDADGDDVTDGRRTVATWPYGGNFHEFA
                     FGLLYRDGYFYLNLSVAIDLGGATTDPQPAPNRGSTIKVNKETGKVDYIAGGLRTPNGI
                     GWGPEGDMFVLDNQGGWLPSSKLLHIKQDRFFNHYTNPSGPFDAKPVTKPVLWLPQNEI
                     ANSPSAPLQLDEGRFAGQMLFGDVTYGGIQRAYLEKVDGEYQGAVFRFTQGLEAGVNRI
                     SMGPDGAIYAGGLGAGGNWGQEGKLTYGLQKLSPSGDKAFDILAMRAKPGGFELEYTEP
                     LSEETAAKLAESYRVEQWTYAPTPAYGGPKIDEESLDVGAATLSEDRKKVTLTIPGLKA
                     NRVVHVRSPRPFSSADGTELWSTEAWYTLNSLPGDQPPATRYEAEEAALSGGAGFDTEH
                     AGYSGGGFVDNFGNEGAAVAFDVEAGKAGTHDVGLRYSNGPDPAPGTKTVSVHVNGEKV
                     RQIKLLSTTDWKTWSTGTEQLELRKGRNTITYSFDSGDTGHVNLDMITVHPKGARVQLF
                     DGTDQAAWQHPDGRTPEWPVSGGEMEVAGGDLRTKQGFQDFRAHVEFWLPNLPPDVTGQ
                     DRANSGVYLQERYEVQILDSYGDTTLADNEAGAIYTKKAPDVNAATAPETWQTYDITFR
                     AARFDASGAKTEDARVTVVWNGVTVHDDVAVDGTTGGGAAEGPTAGAIKLQDHGSKVRY
                     RNVWVEPLT"
ORIGIN
        1 ctgagcagca gcccgcgctc acgggtgtgg cgggtggaga cggccggggc gcccgtggtg
       61 gtgaagcaga tcgtcgaggg acccgacgcc gacgagcggt acgcccgtga actggccgcg
      121 ttgcggctcg ccgcaggagc cgatccggcc gtggtacccg cactgctggg caccgccccc
      181 ggcgaccggg tgctggtcct ggagcatctg gaccaccaac accccaccgg cgactggatc
      241 gtggactacg cggcggcact ggcccggctg cacgccgtcg cccgccccga gcacaccgga
      301 gtgctgcccc gctggcaggg cccggacgag gccgacgccg cctccttcct ccggctggcc
      361 gcggccctcg acgctcccgt ccctcccgga gtgcccgggg agctcgacgg cctcgtgcac
      421 cggctcgccc gggcgccggg gcacgccctg ctccacggcg acccgtgccc cggcaacgac
      481 ctgcacaccg ccgacggaac ccggttcatc gacttcgaac atgcctcact gggcagcggg
      541 ctgatggaac tcgcctacct gcgcatcggc ttcccgacct gctggtgtgt cacctcggca
      601 cccgccccgc tgctggaacg ggcggaggcc gtctaccgca cggcatggcg cgccgagacc
      661 ggcgacgaac tccacggcga cctcaccgac ccctgcgccg gctggctgat ccggggagac
      721 gccctggtcc gcagagctca ccgcggaggc accgatcacc tggcccggat cccggtccgc
      781 gactggaaat ggggcacggc gaccgcccgg cagcgcctcg tccaccggct cggtgtcgtc
      841 ggaggtatga ccgccggcca cgacggtctg agcgggctga gcactctctg tacggacatg
      901 cgccggcaga tgctcgcccg ctggcccagg ctccgacccg tccccgcaca acgcccctga
      961 gccgaggccg ctcgcgacac gggccgacgg ccgtcgaggc ggggggagtc gccgacgggc
     1021 gtcagcgggc ccaggccggt gtccaggcgt cggccggcga cttcggccgc acctgcacga
     1081 ggtacctccg cagcgccgcc agaaccggat gcgggttgcc cgtccggtac aggaacacgt
     1141 gcggatagac cggcgtcggg cccaccaccg ggatccgccg caggtcatgc gcggcaggcc
     1201 ataggtacct gtcccgggag ccgacgagtg tggcgagcgc ggcggagtcg gcgatcgagt
     1261 ccatcagcgc ctcggtcccg aagtcgggcc cgaccgcgtc gatgcgcaga ccgaagtcct
     1321 ccgcgagccg gtcgtagtag gcggcccact cggtgccctg cttgatgccc gggatccaga
     1381 tccggtgccc ggccaggtcc gccggggcca acgaccgggc ggaggccagc gggtggcgcg
     1441 gcccgacgag gaggtgcaac ggatcgtcca ggacgcgttc ggcgctgatc ccgtcgggca
     1501 gcgcacccac gggaacggcg cggaaggtcg cgtcgatctc gccggcccgc accgcctcgg
     1561 ccgcccccgt cacgttcgtg tccgcgagcg tcaccacgtc caggtccgtg ccggggtggg
     1621 cctggtagaa gccgcgtacg gccagcgccg gggcgatacg ccggtggagc acgtccacac
     1681 gcagcacccg gtcccccgga cgtaccgagg aggcggcccg ctccacggcc cgcagcacct
     1741 cgcgggcgtg gggcaggaac gcctgcccgt ccggagtggg gtgcgctcca cgggcggtac
     1801 ggacgaacaa cgtcaccccg agcacacgtt ccaggcccgc cacgcgcttg gagacggcct
     1861 gctggctgat gcgcagctcc acggcggcct cctggaactg cccggtgtcc gcgacggtga
     1921 cgaacgtgcg cacggcttcg atgtccacgc cctgaaccct atgtgggcac aacccatggt
     1981 tgtggcacgc cgacagcagg ggctggagca ggggctcccg agcgcacctt gcctcaatgg
     2041 catacgctca tgcttatgac gcaagaagat ggtgagctgg acagcctggt acgcaaacgc
     2101 atccgcgccc tgcgcgtggc ccagggctgg tccctggagg agctggccgg ccgcgcgaag
     2161 gtcagtcagt ccacgctcag ccgtatcgag aacggccggc gccggctggc cctggaccag
     2221 ctggtcacgc tcgcccgcgc cctggacacc tccctcgacc agttggtcga gaccgcctcc
     2281 gacgacatcg tctccaaccc gatgatcgac ggggcccacg ggcagatgcg gtggcccatc
     2341 aaggcggaac ccggcatgac cgtcatccgt cagcgcatga ccgagccgcc gcccgacaac
     2401 ccttcacgcc tgcgtgcgca cccgggccgc gagtggctcg tcgtcctctc cggcaccgcg
     2461 atcctgctcc tgggcaaccg gcgcctgcgg atcgagacga accaggcggc ggagtttccc
     2521 acgatgcttc cgcacgcgat cggcgccgag ggcgggccgt gcgagctgct gggcatcttc
     2581 gaccgggacg cccgccgcgg ccatcagcgc ggggaaggcg cggagcaggc gaaccgcccg
     2641 actccgccgc ccgggcggag cctcccgtga cgagcgcggg gcagcgattc ggggtgcccg
     2701 ccgcacgatc agggcccaag cccctcgcgt acgcccggac caggggacgg ggggccnnnn
     2761 nnnnnncccc ccccccccgg cgccggtccg cgcggctgac ctgccgcgcg tctcagcagc
     2821 tcacgcggga tcgacgcggg agaccacgcc accgctgccg aggacgtaca gctcgccgtc
     2881 accgccctcg acgaacgaga tcacctcgcc gccgctgact ccgaggtcgc cgacgccggt
     2941 cacctcgccg tccttcatct ggagcgtacg cagggtgccg tcgcagtagt cgctgaacac
     3001 atagctcccc cgaagatccg ggagtgcgtc gccgcggtag acgaatccgc cggtcaccga
     3061 gcagccgagg cccgtacggt cgtactcgtg gaccggcggg acgtggttcg cgggctccgt
     3121 gccaccccgg aagggatggg tgccctccat ggaggcccag ccgtagttct ccccgccctt
     3181 gctgtccgcc ggggcccagt cgatctcctc ccagtcgctt tggccgacat cgccgatcag
     3241 caggtcgccc gtgcccgcgt cgaaggagaa acgccacggg ttgcgcagcc cgtacgacca
     3301 gatctcgtcc ttcgcgttcg cgtcgtccac gaacgggttg tccgccggga tggcgtacgg
     3361 ctcgccgccg gtcgggtcga tccgcagcag cttgccgagc agggtgtcga gcttctgccc
     3421 gttgccgtgc gggtcgccgc ccgagccgcc gtcaccgaag gcgatgtaca ggtagccgtc
     3481 ggggccgaac ttgatgtccc cgccgttgtg gttcgcgtac ggctgggtct gggtgaggac
     3541 ggtccgccgg gaatccggct ggagccggcc gccctccacg gcgaactcgt ccaccgtgct
     3601 ggtgccttcg aggtccgtga acgagatgta gaagtgcgcg aacgtcttgt cgaacgcgac
     3661 gccgagcaag ccgcgttcgc cgtccgtggt ggtctcgtcg gagatgtcga gcacgggtgc
     3721 gccgaggccc tgatcgtcca ggacccttac ggtgcccgcg cgttcggcta tccacagcgt
     3781 gtcatcgggt ccggccgccc cgccggacgg gccctgggcc ctggccactt cggtcaggga
     3841 cgcgctcacc ggcttgaccg gatcggcggg ctcgacggcc gacgccgtgg ccagggtcag
     3901 ggacgtgacg aggcagagcg tgccgatgat cgccgagctt ctggtgcgaa atttcaccgt
     3961 ggcctcctgg aggcggcgaa tgggggaggt cacccggctg ctcgagcgga gttgagtggg
     4021 gggcgcgagc cggcaggcaa cctgggtggg ggagttggtg tgtcaccggc tacaggtgag
     4081 gataggggga cggacgtggt ctggcctaga ccagcgttac ggcatcttct tccgcggtga
     4141 cgcgcgcagc ctccgcaagt cggtagtcgg ccaaatcgtc gacgcgaacg cgaccggtga
     4201 tgcactcgtg ccgccagttc agtccgagat gggagcgctc caactccctc caactgccct
     4261 tccatgcaag gttattgcgc tgcaccgctt gacagccatc ggatgccgcg tcagtttggg
     4321 agcgctccca catgcatgct tcccccacct gaacccctta cctcctgagc gtcacggacc
     4381 cctgaaaccg tccgtcgaca cccccgacgg acgtacgaga ggagcacgga gccgcaatga
     4441 gaagcagagg cgtcaccccg cacgcaccgc acgcattccg caggagagcg gccgccgcac
     4501 tgtccgcact gatcatgggt gcggcactcg cggtggccgt acccggacag gcgtcggccg
     4561 ccgcccgcgt cgacaacccc tacgccggtg ccaccgcgta cgtgaacccc gactggtccg
     4621 ccagggccgc cgccgagccc ggcggcgaag tcatcgcgga cgagccgtcg ttcgtctgga
     4681 tggaccgcat cgccgcgatc ggcggcacac ccggcgcgcg aggcctgcgc gcgcacctcg
     4741 acacggccgt gagtcaggga gccgacctct tccaggtcgt catctacaac ctgcccggcc
     4801 gggactgcgc cgcactcgcc tccaacggcg aactcggccc caccgagctg agccgctaca
     4861 aggacgacta catcgacccc atcgccggca tcctcggtga ccccgcctac gcgagcctgc
     4921 gcatcgtcac actcatcgaa ccggactcgc tgcccaacct cgtcaccaac gccggaggga
     4981 ccgccggctc cacgcccgag tgcgccacga tgaaggccaa cggcaactac gagaagggca
     5041 tcggatacgc cctgcacacc ctgggcgccc tgcccaacgt ctacaactac gtcgacgccg
     5101 cccaccacgg ctggctcggc tgggactcca acttcgtccc cgccgcacag cagttcaaga
     5161 aggccgcgac gacggagggc gccaccgtct ccgacgtcca cggcttcatc gtgaacacgg
     5221 ccaactactc ggcgctcgag gagccgcact tcgcggtgac cgactccgtg aacgggacca
     5281 cggtgcgcca gtcgcgctgg gtggactgga actactacgt ggacgagctc tcgttcgcca
     5341 aggccctgcg cacggaactg gtccgccagg gcttcgcctc cgacatcggc atgctcatcg
     5401 acaccgcccg caacggctgg ggcggctccg cccggcccac cggacccgga ccgctgacca
     5461 gcgccgacgc ctatgtcgac ggtggccgga ccgaccgccg catccacgcg ggcaactggt
     5521 gcaaccagag cggcgcgggc atcggcgagc gccccaccac cgcccccgag ccggggatcg
     5581 acgcctacgt ctgggccaag cccccgggcg agtccgacgg cagcagcgag cccgtcgaca
     5641 acgacgaggg caagggcttc gaccggatgt gcgacccgac gtacaccggc aacggccgca
     5701 acggcttcaa cctcacgggc gccctgcccg actccccggt ggccgggcac tggttctccg
     5761 gacagttcca ggagctgctc cgcaacgccc acccgccgct ggacggcggc agcggaggcg
     5821 aggaggacac ccaggcgccg accgtgccca cgagcctgcg ggtgacggcc aagtccagca
     5881 gcagcgtcac cctcgcctgg gcggcgtcca cggacgacac cggcgtcacg gggtacgaca
     5941 tcctccgcga cggcgccccg gtagggacga ccgccgcgac gacctacacg gacactggcg
     6001 tgagcgcctc gaccgcctac agctactcgg tcagggccaa ggacgcggca ggcaacgtct
     6061 cggccggggc cccggccgca caggtcacca ccgaggcggg cggcggcacc ggaacgggag
     6121 cgctcaaggc cgaataccgc aacaccgacg gatccccgac cgacaaccag atccggatgt
     6181 ccctccgcct ggtcaacacc ggttcggccg cgatcgacct gtccacggtc accgcccgct
     6241 actggttcac ccccgacggc ggtgcgagca ccttcggcac cgcctgcgac tacgccgtgc
     6301 tcgggtgcgg aaacgtgacg cacggcgtcc ggtcggccag cgcaccggcc accggcgcca
     6361 gccactacct ggaggtcggc ttcggcagcg gcagcctcgc ggcgggcgcc acgaccgggg
     6421 agatccaact gcggctcaac aagagcgact ggtcggcctt ccaggagagc gacgactaca
     6481 gccgctccac caacaccgcc ttcgccgacg ccccgagggt cggtgtcttc accggctcca
     6541 ccctcgcctg gggcaccgcc ccctgacctg gaccgccacc gtttccggca cggcatctgc
     6601 cgctgcccct ctccccggac gacgggagag gggcagcggc gcggaatccg ggacggacag
     6661 gacctgggtc agtgcacgtc gacccggtcg ccggagccga tcgtgcccag acgggacgac
     6721 gtggccttga actgcgcctt ccaggtgccg tccttcttgg cggtgaaccc cttcgagaac
     6781 acgcccttgc cgttggtgcg tacggtcgcc agcttgctcc acttgctgga tccgtcggcc
     6841 ttgaacagga cgatcacgga ctggccggag gcgttcttcc aggtgccgtc caggctgcgc
     6901 agggtgccct tgacggtgat ggtgcgcccc ttgcggaccg gctcggggga ggcgttgaag
     6961 ccggagacgg cggtccgcag cttgacgtcc acgttgtcgg aggagctgac ggccgcggcg
     7021 cggtcggcgg tccccgcgta acgggcgcgc caggtgccgt ccttgacggc ggtgaccgac
     7081 gccgagacga cgcccttgct gttggcggtg accgtggtgg tccggctcca ggtcttgccg
     7141 cccttcgacc ggaactcgat cacgacggga gtcttggcca gcggacgcca cacgttgtcc
     7201 gtggcggagg cggtctggag cgtggcgacc accttcagct tggagccctt gcccaccggc
     7261 tcgggcgagg cgttgaagga gacgatccgg gtcggcacgg cggacaccgt gagcgtggcg
     7321 gccgacgtgg ccgtctcacc ggaggcgttg acgaagacgg cacggtagcg gtggccgtcg
     7381 agggcggcgg ccgccttcac cggcagggtg gcggtggtgg ccccggggac ggtgctccag
     7441 gtcgtgccgc ggtcggtgct gcgctcccag cggaccgagt ccgcgccggt cgcggcggca
     7501 gtgaacgtgc cggtcgcgcc cgagcggacg gtacgcgacg cgggatgctg ggtcacggtg
     7561 gcggcgggga cctcgacgcc gaaccggagc ggctgggcga cgtcctgggc ccgggagggc
     7621 atccaggtgg ggtcgccgcc gtcgtgcgag ttgaagctcg tgacgaagca ggcggtggtg
     7681 cggcaatcga cgacgggggc cccggagggg gtgaaggtct cggtgagctt cagtgtgacg
     7741 ctgaaggtgc cgtccgcgcc gacctgacgg atgtacgccg cgttgccgaa gacgctgggg
     7801 taggtggtgc cgggaagggc gatggactgc gccagataca cgccgcgccc gggctggtag
     7861 cccttgccgc tgacggtgac ctcgttctcg gcgcccagct cgctgacctg gctgaccgtc
     7921 agcgtgggga cgctgacgcc gccgctgatg gcgacggggt ccagcgccgt gccggccggg
     7981 tacatgggcc ggccctggta ggcgaagatg gccgagccct cttcggtgag cgtggccgtg
     8041 atgcccgtcc agtcgaggac ggctccgtcg agggcgtcgg cggacgccgt gagcgcggcg
     8101 agcggcacgc cgggagtggt gaccggggcc tggccggcgg cgatgtcggt cgtcacgtcc
     8161 atgtggagcg tgcccttgcc gtccttgagg acgacacgcg ggttggcgag cgtgatggcg
     8221 gttatcccgt gactcgggac cgcgtaggtg accgagccgc cgaagcgcac atcggcggac
     8281 cgctcggcag ggtccaccga gccgtgcttg acgggatagt cgacccgtcc ggccgcatcc
     8341 gcacccgcgc cgccggccac gttcaccgag ccgcccatgc cggtgacgta gcggacccag
     8401 gagtccttga agccccagga ggaccggccg gtcaccagga tcggggcggc tgccgacgtc
     8461 gtgccgccgg cctcggcccg cgcggcggcg tggacgccgg gggcggcgga ggcgggaacg
     8521 gcgaggacgc ctgcgcccac ggatacgacg gtcagggcgg cgagtgcggc caggcggcca
     8581 cggcggggca tggacatgcg ctgcatgtct ccttcgggag aggggcacgg cgcacgtctg
     8641 gacggagccg ttcccgggag gcgaacgaaa gaagggggga taccggcttc tcggcgtgtg
     8701 gggacccgaa gacgactcat cgaatattag gtgaggctta cctaattgtc accatggggg
     8761 tgtgcgaccg gagacggtga cggagggcgg cttccagcgg gagcgggacg ccccggcgga
     8821 gacgccgtac tcctccttga gctgttcggg gatggcgtag tgcatcacgc gtccgcgggt
     8881 gagggaggac agttcgagga cggtggtgag gtggccgagg cggtccaggg cccaggcgcc
     8941 gaggggagac cggtcctcga cggtctccag gatgccgaga aggtggggta cggccttgac
     9001 ggcggtgtcc cacgaggtgc gcggcacctg gagccagtcg gcgcaggtgt cgccgaccag
     9061 gtgccggatg agcgctgaga cgatcgggtc gaagaaggtc ccgggcacga cctcctcgta
     9121 gaggtcgatg agctgccggg tcagcagcgc gccctcctcg gaggggccca tgtgccggat
     9181 catgtacagg tcgaggaact ggcgggcctc gtccagggac cgcgggacgg actcctggct
     9241 gacgcccagc atcgccccga ccacacgcca ggcgtagtag taggccgccg cgccctcctc
     9301 cgacatgtgg atgccgagac ggtgcaggct gtcgagcacg agcagcgaga agaacatctg
     9361 cccgccgatc atgtcctcct ggcagatcgg cgtcccgagc gcgtcggtgt cccaccgttt
     9421 ctcgcgcagg aggtgatggc ggatcgacgc gtgcagaagg cggaccttct gggcggcggg
     9481 gacgaagcgg cccccggcct cgaaggcgtc gggccgcatc aggtagacgg tgaactggcc
     9541 ggtctccgcc atccgtttgg aggggtactt cagcccgtgg gtcgccgaaa gaagcttcgc
     9601 cacgtgcggg accacgtagc aggcaggcat ggaggcgaac gacagtgcgg tggaaatatg
     9661 cacgttgttg tcgatgaaga acagccgggc cttctccatc tcctcccaat cgacccagtc
     9721 cggcggggca cttgtggcct gaaggtagtc ccgggcgaca tcgggcagcc cgtccggcag
     9781 gggagcgccc gcggtggaga cgtagcgcat cagtgtgttg aacttgccca cctccccgcg
     9841 gtcgaagagg gcggcgacgg tcgcgtcggc cagttcgtcg cccccctgcc gcagggcgtt
     9901 catcgaagcc tcggtgtagg tcaagacgga cttccttgtt ctcgatgcga tgcggtgcgg
     9961 tgcggtgcgg tacgggtgtg tgcggcgcgc gaacgcgggg tcaggacagc cggacggtcg
    10021 ccgaattcgc cagcgccgcc agggcgtcgg ccgcacgtga cggcacgtcc agctcatgga
    10081 gggcgtcgag ggcttcctcc acgcgcgccg tgatcatgtc ttcgacgagg ccgggggtct
    10141 tcagcctgcg catgacgtcg cgcaccgcgt ccagcccgtc ctcgtccagg tcgcgcctgc
    10201 ccagaagagc ccggagccgg tcacggtcgt cgtcaccggc gacacgccag gtctccgcca
    10261 gcagggccgt gggccggtgg ccgcacacat cgtcggcatt ggccttgccg gtccgtcccg
    10321 ggtctccgaa cagcccgagc agatcgtccc tcagctggaa ggcctcgccc agcggcagtc
    10381 cataggcgga gtagccctcg cgcagccgac cgccggcccc ggccagcgca ccgccgatca
    10441 acaggggctg ctcgacggtg tacttggcgg tcttgtaccg gatcaccttc agcgaggccc
    10501 cggtgtccgg ctccgccccg gtgcgcagga tctccaggca ctcgcccgcg atcagctccc
    10561 ggcccagaac ggtccacagc gggcgggccc ggcccagata gacggcgggc aggccgctgg
    10621 tggtgaacag ctgtccggcc atccccatca gcagatcgcc caccagcatc gccagcgatc
    10681 tggcggcggc gacggagcgc gggcgacggc gtacggcgcc gcgcagagcg atgtgcgcgg
    10741 tgggccggcc gtgccgcaga gcgctgtcgt cgatgagatc gtcgtggacg acagcggcgg
    10801 cgtggatcag ctccagggag gccgccgctc gcaccagcgc ggcgctgtcc ggctgccccg
    10861 ccgcccgcca gccccagtag cagaacgccg cccgcagccg tttgccgtcc gcgacggctt
    10921 cctccacctg cgcggccacc ggagccaggg acgggtcgat cgccgcgaac agatcggcct
    10981 cccgggcgac gaacgggtgc agcacctcgt cgacccgcgc cttgaacgcc gccgtgtccc
    11041 accggtcagg cgtcatcgga ggcccgccgg gcgacgacat gccgggcgag cagctccaga
    11101 tgggccggcg gcggggcggc gtaccggtcc agcaccaggc gcccgcgcgc cgtcagttcg
    11161 tgctcggcct gcgccgccag ttccgcggcg tccgaacggc gcagcagccc gcgtaccgcg
    11221 cccagggccg aacccaccgc gctcaccgcc atatcggccg cgcccgccac gagcaggacc
    11281 acccgctcgt ccagatcccc gtcacgcccc gcttctcgcg tcatgccact ccccaccccg
    11341 gaactgtcga cggcgcaggt cacgcgcccg tcccacagca tcgcgacgca ccgggagccg
    11401 aaggggcgga agtcacgatc gagtgcgcaa ctagctcagc tgtgcggttc tacgacggaa
    11461 tcggtgaggc atacgccgga ccgcctccgt cccgcccccg tggatgcggt gggcgggggc
    11521 gatccctcag cgccgaaggc cagcgttgag ccgggcggcc cggcgcgtga ggtggtcgcg
    11581 ctcggcgagc gtgggggcct tgtgggcggc ttccgcgtac agccgggccg ccgtcggcag
    11641 gtcgccgtca cgctcgtgga gatacgccgc caccgccgtg tggcggggca acgtgtcgct
    11701 cagcgcggcg agttcggcca gaccggcgcg cggtccgtcg gcctctccga cggccacggc
    11761 ccggttgagc cggacgaccg ggctgtccgt cagacccacc agctcgtcgt accactcgac
    11821 gatctgcacc cagtcggtct cctcggcggt cggcgcgtcg gcgtggagcg ccgcgatggc
    11881 ggcctgggcc tggaactctc ccagccggtc gcgggcgagg gccgcctgca ggatcccgac
    11941 gccctcggtg atcgccccgg tgtcccagcg gccccggtcc tgctcggcga gcggcaccag
    12001 gctcccgtcg ggcgcggtcc tggtggctcg gcgggcatgg tggagcatca tgagggcgag
    12061 cagccccgcc acctccgggt ggtcgatcgc ggccgcgagc tgccgggtga gccggatcgc
    12121 ctcggcagcg aggtcgacgt cgccggaata gccctcgttg aagaccagat agaggacgcg
    12181 cagcacggtg gcgacatcgc cgggctgatc gaacggcacg ccggagacgg tgcgcttcgc
    12241 ccggctgatg cgctgcgcca tggttgcctc gggcaccaga taggcccggg cgatctggcg
    12301 ggtcgtgagc ccgccgacgg cgcgcagcgt gagcgcgacg gcggacgacg gcgtcagcga
    12361 cgggtgggcg cacaggaagt agagctggag cgtgtcgtcc gccgccggta cggggccggg
    12421 tgcgggctcc tcgtcgacga ggtcctcccg ccgccgccgg gcggcctccg cccgggtcgc
    12481 gtcgaggaac cgccgccagg ccacggtgac cagccagccc ttcgggtccc gcggttgctc
    12541 gtccggccat acgcggaccg cctcgaccag ggcgtcctgc acggcgtcct cggccgccgc
    12601 gaagtctgct ccgcggcgga cgaggatccc gaggacgctc ggcgtgaggc tcctcaggag
    12661 gacctcgttc atcgtggtgt cactccgtga cggtgggcgg cgcggacagg aacgggcgga
    12721 cctccagcca ctcgtggatc ggcttcccgc ccgcccccgg agcggccgac agctccccgg
    12781 ccagctcgac ggcgcggtcg tagccgtcga catcgatgat catccagccg gcgatgaggt
    12841 ccttggtctc ggcgaacggc ccgtcggtga ccggcgggcg gccctcgccg tcgtaccgga
    12901 cccacgcgcc ctcgggggcg agcgccgagc cctcgacgaa ctccccggtc ttctccagcc
    12961 ggtcggcgaa gtcctgcatg tactgcatgt gcgccgagat ctcctcgggc gtccaccggt
    13021 ccatcggtac gtcgttgacc gctgccgggg ctccgcggta gtgcttgagc agaaggtact
    13081 tggccatggt gttactcctc ggtcctgtgc ggcccattgt ggccgccttc actacgggga
    13141 cggagccgga cgcgggttct cgacatcgtc gcccgaaact tctcgacttt tttccggcgg
    13201 gccgggacgg gcccgcggtc actgctcgcg caggccccac ggggatccgt acgcgacgag
    13261 cagatccagg aacgggcgcg gggccagcgc ctcggcgccg agcacgcccg caccgctcca
    13321 gacgccgctc gccaccagtt ccagggcgat caccgggttg atcgccgtct gccagaccac
    13381 ggcctgcgag ccgtactcgc gcatcgacca ctggttgtcg accacgtggt agaggtacac
    13441 gtcgcggggc gcaccgtcct tcgtgcccgt gaccctggtg ccggcacagg tcttgccccg
    13501 catgagttcg ccgagggagg ccgggtcggg cagacaggcc gccaccacgt cacgggggga
    13561 cacctcgccg ccgggcacgg tcaccttgtc cgtgcggtcc aggccgaggc tgtgcagggt
    13621 cttgagggtc tcgatgaact cgtcgcccag cccgtacttg aacgtgacgc gccgggactc
    13681 cacccagcgc gggatcagca ggacctcctc gtgctcgacg ttgacgcatg cgaccggacc
    13741 gatgccctcc gggaagtcga agacctccgg ctcgctgaac ggggccgtgg tgaaccaccc
    13801 ccggtccctc tcccagacca ccggcgggtt cagacactcc tcgatggtgg tccagatcga
    13861 gaacgacggg gcgaagtcat agccctcgac ggtgagattc gcgccgtccc ggacgccgat
    13921 ctcctcgatc tcgtcgaaca gctcgtccgc cgcgtaccgg gcgaagacgt cggacagccc
    13981 cggctccacg cccaccccga cgagcgcgag ccggccggcc tcctcccacg ccgccgcccg
    14041 ctcgaactgc cgatcgccga gcttcacccc gcactgctcg tacgggcgct ccggatgcgg
    14101 caaggacagg gacatggcca tgtccagata gtcgaccccg gcggccagtg ccgcctcgaa
    14161 cagcggcatc acgaaccggg ggtcggtggc gttcacgagg atgtcgcacc gctgctcggt
    14221 gaggagcgcg gtgaccgccg cccggtcgga ggcgtcgatg cgcagagcgg tgaatctggt
    14281 ctcctccccg ccgagcgcgg ccaccgcggc ctcggcccgg gaaaggtcgt aatcggtgac
    14341 gaccatgtgg tcgaagaagg agcggcgggc ggcgatcctg gtgatcgccg tacccacgcc
    14401 acctgcgccg acgagcagta cgcgcatgcc ggatgtgcct ttcgtcagag agacgggccg
    14461 tgaggaccgg tgccccttgg attcgtccag gcaaggggtg cgcttgagtt gcgtcaacgc
    14521 tgttggcgta acggcggggc ccggcaggcc gcaggtcacg ctccgcccga gcctcggcgg
    14581 tatccgcacg ggctccgcat ggcggacccc ggggccacgg cgcagactgg ccggagacgg
    14641 aaaaggcgac tgccccggag aggcctggaa cgatgggtga gtacgcggat ctgcccggcg
    14701 tcaggacctg gtacgagacc gaggggaccg gcgacccgct ggttctgctg cacggcggct
    14761 tctgcaccaa tgacacgtgg ggcgcacagc gcgccgacct ggcctccacc taccgcgtgt
    14821 atctgccgga acggcgcgcc cacgggcaca cggccgacgt cgcggggccg ctgacgtacc
    14881 aggacatggc cgacgacacc gtggccttcc tggaggaggt cgtcggggga ccggcgcatc
    14941 tggtgggctg gagcgacggg ggagtcgtcg cgctgatcgt cgccggggac cggcccgacc
    15001 tcgtccgcaa ggccgtggcg atcggggcca acttccgtcc gggccccgag tgtttcgtcg
    15061 agccgtcgat gctcgacgcg atgacgccgt ccgggcccga tctcgcgttc ttccgggagt
    15121 tgtacgagcc tgtctcaccg gacggcgcgg gccactggcc ggtggtggcc gagaaggtga
    15181 tcgacatgtg gcgtacgcag ccggcgctga cggccgagga cctggcccgc gtcggggcgc
    15241 ccaccctggt catggccggc gacgacgacc tgatgacgct ggagcacacg accgccctgt
    15301 accgcgcgat cccggacgcc gagctggccg tcgttcccgg ggcgtcccac ctggtcccgc
    15361 tggagaagcc gacgctcgtc aaccggttga tcctcgacca tctcgcacag gaggcggtgg
    15421 agacgatgat gcccatccgg cgggcggaga ccggggcccc ggagggcgcc gagatctgag
    15481 ccgacggcgt cgaggaccgc ggggctcatt cctccgtgca gctgaagtcc tgcggggagg
    15541 tccgcagctt gcccagcagt cggcgcagcg tggccaggtc gcgctcggac aggtccgcga
    15601 agagttcgtg ctccacggtg tcgagtgccg tgtccgaggt ccgcagctgc gaggcgcccc
    15661 gcggagtgat ctcgacgatg tgacggcgtc ggtcggcggt gtcacgacga cgccgtacga
    15721 gatcgtcgcc ttcgagatcg ttgaggaggg cgacgagaac gctggggtcg acgtcgagcc
    15781 tctcgatgag cgccttctgt gtgaccggac cgtcggcgag ctgcaggagc gtcatcatgt
    15841 gccgcggggt gagcccggtg gccgcgagcg ccttgtggat cagagtctgc gtcgcgttgc
    15901 cgtggtaggc gagcaggaat ccgaggcgct ggtccggatc gccgggagac gtcgaaggcc
    15961 ccgccgatgg ctgggcggcc ctgtcctgag ctggcattcc accacggtat cagggcacgc
    16021 attgtggaag cttaaaaatc gtttatagtc gtcaacgatc tagccattca catcattgat
    16081 gatcccgagg taaccatgtt catcgcctac gccgtggtcg gcgtccttct cgccctcgcc
    16141 ctcggcgcct ccgccgtgct gacgttcacg cgcaacgagg ccatcacggc ctcgatgggc
    16201 aaagtgggcg tccccggcac ctggttcccc tggctggcct cgctcaaggc ggccggcgcc
    16261 ctcggcctcc tgatcggcct cggtgtgccg ctgatcggat ccgccgccgc catcggcgtc
    16321 gtcctctact tcatcggagc cgtcgtcacc cacctgcgcg tcaaggacta cgagatcgca
    16381 ccgcccgtgg tgctcgccct gctggcggcc gccgcgctgg tcctgcgcgt gctgtcggcc
    16441 tgaacgcccc gagcgcagcc gggcgtcacc cgagcggacg gcggcgcgat cggctgcttt
    16501 cggccggcgg cggcgcggtc atccgaaaga ggccggatgt cagcatcggg cgagatattc
    16561 acatttatgc tggctcgatg cgatctgctc cctggtgggc cttggtctcc tccggatgcg
    16621 cccccgtcct tctgaccggc tcctggatga ttgcgcagct gcgccaggga ccggcgtacg
    16681 accccgagcg acagaccctg agcgtgctgg cctcctacgg cgctgccagc tactggctga
    16741 tgacggggat gctgctggtg ctggggacgt gctacgtggt gacggcgcac gcgctccggc
    16801 cggcggcgcc cgccgggcgg gtcgccctgg cctgcggcgg actgtgcgca ctggccctga
    16861 cgctggtgcc cgccccgagc agcggcgggg cgttggagca cggggccgtg tccaccgtgg
    16921 gcctcgtgct gctggcggtg tggcctcccc tggccgcggt ccgggaccgg aagccggtgc
    16981 cgtgggggct gaggctcgat gtgtcgctcg ccgcgagcgc gttgatgtgc gcgagcgctc
    17041 tgtggttcct ggcggagctg cagagcgcga gggcgcccgg cgtcgccgag cgcgtggtca
    17101 cgttcgtcca ggcactgtgg ccgttcctgg tggtcgtctc ctgccggaga agcgcggcct
    17161 gaccggagcg aagcccgcgg acgcgaacgt gtacgcgcct acacgtcgcc cgccacgccc
    17221 cgcagccagg cgccgacagc cgtgtagtcg cagtccgcca ggcctcgccg gggatccacc
    17281 cggtggagca gggcggggcc cgggtggtgg acggcgaccc aggcccgatc ggtgtcggtg
    17341 atctcgtcgt cgacccagac gaaaggacgg ccggcggccc gagcgacgag ggcgcgggtc
    17401 ttccagtgca gcccgtcccg ctcgtcctgg tcctcccgtc cgtcggcgcc gtcggcgtcg
    17461 gagggttccg gccagtggac gacgggcaac ggcggcaggc cgatgcgggg ggcgatccac
    17521 gcgttcgcgt cctccatcca cgtggtcgcc cagacgagct cgcagggcag cgccgcgagc
    17581 cggggcccgt gctgaggatt gaccctggtc aggagcggat tcgcaccggt agccggagta
    17641 ccagggccca tctcgtacgt cgggtggggg cgggacgtcg cgccgaaggg aatgagcgga
    17701 ccgtcgacgt cgaggaacag cagcggacgc tgcgcggtgc gagtcacggg agcacgatag
    17761 cgacgtcccc acccggcccc ggcgtcaggg ccgggaccga tagcgcggcg cggcgcgagc
    17821 gccggtgcgg acggttccgg ggcgacagcc gatcgctgcc accccggaac cggtgcgccg
    17881 gaccgcccta ggtgagcggc tcgacccaca cgttgcggta gcggaccttg ctcccgtggt
    17941 cctggagctt gatcgccccg gccgtcggac cctcggccgc tccgccgccg gtcgtgccgt
    18001 cgacggccac gtcgtcgtgg acggtgacgc cgttccacac gacggtgacc cgggcgtcct
    18061 ccgtcttcgc gcccgaggcg tcgaagcggg cggcgcggaa ggtgatgtcg tacgtctgcc
    18121 aggtctccgg ggccgtggcg gcgttcacgt ccggggcctt cttggtgtag atcgccccgg
    18181 cctcgttgtc ggcgagcgtg gtgtcaccgt acgagtcgag gatctgcacc tcgtagcgct
    18241 cctgcaggta cacgccgctg ttggcgcggt cctggccggt cacgtccggc gggaggttcg
    18301 gcagccagaa ctcgacatgg gcacggaagt cctggaagcc ctgcttggtg cgtaggtccc
    18361 cgccggcgac ctccatctcc ccgccgctca ccggccattc gggagtgcgg ccgtccggat
    18421 gctgccaggc cgcctggtcc gtgccgtcga agagctggac gcgggcaccc ttcggatgga
    18481 cggtgatcat gtccaggttc acatggccgg tgtcaccgct gtcgaaggag taggtgatcg
    18541 tgttgcggcc cttgcgcagc tccagctgtt ccgtccccgt cgaccaggtc ttccagtcgg
    18601 tggtcgacag cagcttgatc tgccgcacct tctcgccgtt gacgtggacg ctcaccgtct
    18661 tggtgccggg cgccggatcc ggcccgttgg agtagcgcag acccacatcg tgcgtccccg
    18721 ccttcccggc ctccacgtcg aaggcgaccg cggccccctc gttgccgaag ttgtcgacga
    18781 agccgccgcc cgaatagccc gcgtgctcgg tgtcgaagcc cgcacccccg ctgagggcgg
    18841 cctcctccgc ctcgtaccgg gtggccgggg gctggtcgcc gggcagggag ttgagggtgt
    18901 accaggcctc cgtgctccac agctccgtgc cgtcggcgga gctgaagggg cgcggcgacc
    18961 ggacgtggac cacacggttc gccttgagcc cgggaatggt cagcgtgacc ttcttgcggt
    19021 cctcggagag ggtggccgca ccgacgtcga gggactcctc gtcgatcttg gggccgccgt
    19081 aggcgggcgt cggggcgtac gtccactgct cgacccggta gctctcggcg agcttcgcgg
    19141 ccgtctcctc ggagagcggc tcggtgtact ccagctcgaa gccgcccggc ttggcgcgca
    19201 tcgccaggat gtcgaaggcc ttgtcaccgc tgggggagag cttctggagc ccgtaggtca
    19261 gcttgccctc ctggccccag ttgccgcccg cgccgaggcc gccggcgtag atcgcgccgt
    19321 ccgggcccat gctgatccgg ttgacgcccg cctccaggcc ctgggtgaag cggaagaccg
    19381 ccccctggta ctcgccgtcg accttctcca ggtaggcgcg ctggatgccg ccgtacgtga
    19441 catcgccgaa cagcatctgc ccggcgaacc ggccctcgtc caactgcaga ggagcgctgg
    19501 gggagttggc tatctcgttc tgcggcagcc acagcaccgg cttggtcacc ggcttcgcgt
    19561 cgaacgggcc cgacgggttg gtgtagtggt tgaagaagcg gtcctgcttg atgtggagca
    19621 gcttcgagga gggcagccag ccgccctggt tgtcgaggac gaacatgtcg ccctccgggc
    19681 cccagccgat gccgttgggc gtacgcaggc ccccggcgat gtagtcgacc ttgccggtct
    19741 ccttgttcac cttgatcgtc gagccgcggt tcggtgcggg ctgcgggtcg gtcgtcgccc
    19801 cgcccaggtc gatcgccacg gacaggttca ggtagaagta gccgtcccgg tagagcaggc
    19861 cgaaggcgaa ctcgtggaag tttccgccgt acggccaggt cgccaccgtc cgacgcccat
    19921 cggtcacgtc gtcgccgtcg gcgtcggtca gctcggtgag ttcgtgcttc tgcgacacgt
    19981 acagcttgcc gtcgacggcc ttgatgccca tcggctcctt gagcccctcg gccaccttct
    20041 tggcggtcac ctcgccggga ccggtgtcgc cctggacgtt gtcgaggagg tagacctcgc
    20101 cggtcgtgtt gtcggtgccg ccccaggtgg tcacggcgag ccggccgtcg ggcagccagt
    20161 ccatcgcggt gacctgcggt tcgaagccgg cagggcgcag atcggtgagc gcgtagtccg
    20221 ggtgcgtccc ggccaggggc agtccgtcgc cgggggagtc gagcacgccc tcgcactcct
    20281 tgcgtcccgg cgccgtcacc cgtacgacgt cggcgtcggt gctcagcacg gaagtcggca
    20341 cgacggcgaa atccccggca ccgggcggct tccattcgag ggtgacctgc tggccgccgg
    20401 tgcggtcgaa gtgatcgatg cgcagcggat gatgacctgc cgtcagattc acggtgccgt
    20461 ccttgggctc cgcgccgtgc agcccgtcgt gatcgatgac ggtggagccg tcgatccgca
    20521 gccgcgaacc gtcgtcactg gtcaggcgga aggcgtacgc gccgccctcg ggaacggtga
    20581 ggttcgccgt ggcctgggag acgaagtggt ccccgaagcc gaagtcgtcc gccgaactcc
    20641 agtcgatggc gggcatcaac ttgtcgacgt tcggggtctg tccggccttg atgtcgcaca
    20701 gctcgctgag ggggacctgc acatcgaaga cgcgcagggt gacgcccggt tcctgcggcg
    20761 ggagttcgtc cagcggcacc ggcgcggcgg cggccggcac ggcggacaag gcgccgacga
    20821 gaaacgcgga gaccagcaga ccggtgagat gtctgcggca acggtggagc ggccgtggat
    20881 gcattcttcc tcctggcccc tcgcggcgag gggcacgtcg cggcggtggg tggggccacc
    20941 cggcgcccgg gggtgaacgt tcggctcgtg cggtggggca gcgatgcgtc cggacagggg
    21001 ctccggtggc tgcgccgaga acagtaggag gcttctaccg gcggcgtcca tacttc
//
