LOCUS       NZ_CP096281            20609 bp    DNA     linear   CON 08-JUN-2024
DEFINITION  Streptomyces sp. WAC00303 chromosome.
ACCESSION   NZ_CP096281
VERSION     NZ_CP096281.1
KEYWORDS    RefSeq.
SOURCE      Streptomyces sp. WAC00303
  ORGANISM  Streptomyces sp. WAC00303
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1  (bases 1 to 8548838)
  AUTHORS   Meyer,K.J., Tan,S. and Nodwell,J.R.
  TITLE     Genome Sequence of WAC00303 Direct Submission
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 8548838)
  AUTHORS   Meyer,K.J., Tan,S. and Nodwell,J.R.
  TITLE     Direct Submission
  JOURNAL   Submitted (19-APR-2022) Biochemistry, University of Toronto, 1 Kings
            College Circle 5207, Toronto, ON M5S 1A8, Canada
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: 15-MAR-2022
            Assembly Method                   :: Flye v. 2.8.1
            Assembly Name                     :: WAC00303
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 58.0x
            Sequencing Technology :: Oxford Nanopore; Illumina NextSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_023210535.1-RS_2024_06_08
            Annotation Date                   :: 06/08/2024 05:21:48
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 7,823
            CDSs (total)                      :: 7,731
            Genes (coding)                    :: 7,293
            CDSs (with protein)               :: 7,293
            Genes (RNA)                       :: 92
            rRNAs                             :: 6, 6, 6 (5S, 16S, 23S)
            complete rRNAs                    :: 6, 6, 6 (5S, 16S, 23S)
            tRNAs                             :: 71
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 438
            CDSs (without protein)            :: 438
            Pseudo Genes (ambiguous residues) :: 0 of 438
            Pseudo Genes (frameshifted)       :: 228 of 438
            Pseudo Genes (incomplete)         :: 241 of 438
            Pseudo Genes (internal stop)      :: 26 of 438
            Pseudo Genes (multiple problems)  :: 54 of 438
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 18:23:54
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 7463338
            Orig. end                         :: 7483947
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP096281.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            Bacteria and source DNA available from Justin Nodwell, University
            of Toronto.
FEATURES             Location/Qualifiers
     region          1..20609
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="linaridin"
                     /region_number="26"
                     /rules="(cypemycin or cypI)"
                     /tool="antismash"
     cand_cluster    1..20609
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(cypemycin or cypI)"
                     /kind="single"
                     /product="linaridin"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..20609
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:10609](+)"
                     /cutoff="20000"
                     /detection_rule="(cypemycin or cypI)"
                     /neighbourhood="10000"
                     /product="linaridin"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..10609
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(cypemycin or cypI)"
                     /neighbourhood="10000"
                     /product="linaridin"
                     /protocluster_number="1"
     misc_feature    408..421
                     /note="TFBS match to PsrA, Oleic acid responsive regulator,
                     confidence: weak, score: 18.1"
                     /tool="antismash"
     gene            complement(539..1030)
                     /locus_tag="MWG59_RS34180"
                     /old_locus_tag="MWG59_34180"
     CDS             complement(539..1030)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003964763.1"
                     /locus_tag="MWG59_RS34180"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MWG59_34180"
                     /product="hypothetical protein"
                     /protein_id="WP_179889982.1"
                     /transl_table=11
                     /translation="MSTSDQDQHRDQREDGLNDEEPDRDQERDRGADTPIADTATETKT
                     VAAETVAAAGTETDGVDGSGGEDRGDGQDSQDGKRLTPRQARRLRIALSSVGMAAMALV
                     LGLRIASRSSVLVVGVYGLALILCGVVIELSRNGRTRLASWLLGAGLLAAVGADWLLLP
                     "
     gene            complement(1121..1600)
                     /locus_tag="MWG59_RS34185"
                     /old_locus_tag="MWG59_34185"
     CDS             complement(1121..1600)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007457262.1"
                     /locus_tag="MWG59_RS34185"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MWG59_34185"
                     /product="DUF309 domain-containing protein"
                     /protein_id="WP_097936648.1"
                     /transl_table=11
                     /translation="MNETRRDRDAEGRARNARPRDGLGRPLPYGTPGVERQPEGVVRTP
                     AETLREAQRLLDAGMPFHAHEVFEDAWKSGPEDERELWRGLAQLAVGLTHSARGNTEGG
                     ARLLRRGAGALTPFTGSGPHGIAVSGLCDWARELADRVESGPTVDAAAEAPRLRA"
     gene            1711..4365
                     /locus_tag="MWG59_RS34190"
                     /old_locus_tag="MWG59_34190"
     CDS             1711..4365
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1149: LuxR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018513194.1"
                     /locus_tag="MWG59_RS34190"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MWG59_34190"
                     /product="AAA family ATPase"
                     /protein_id="WP_097936647.1"
                     /transl_table=11
                     /translation="MKPSRPLYEREPELAAAAEAVDALCGAQAVGGLLVFSGEAGIGKT
                     ALLAEIRRMAADRCTVWSARGGETVTSVPFHVVRQLLQPALDQFPPDETRALFGDWYET
                     TAPALGLAEPSGPQPDPQGVRDGLDFVVGRLASRLSHRPLLLIVDDAHWADGESLAWLA
                     SFTARLGELPVLVVQAHRPQELAERDANYIADREAERGFGSKGTVTRVALRALTPDATA
                     VLVRAGLGDHADDPFCREVWAVTGGNPYEAVELVAKVQDRELPPVEESAGELRELGASA
                     RGSGLVARLERLGTNANRFAWAAAVLGTDISQELAATLAGMSSAEAADCTARLRDARIV
                     SGFDPLEFVHPLIATAVYRSIPPATRTAMHGRAAWAITRAGLGAAAASRHLLEVHPDDD
                     QELVAQLREAAGQHLAVGAPEAARRCLERAIEEPPRPKDRAVLLYELGCATLLSSPPTT
                     VQHLRAALDMPGLDDGLRVDATFRLAAALAHNNQLKDAALSLAAEAARTAPGPGLMRLQ
                     AAHFMWEGMQAVEDDGPARSRRLTRNADHLKGRDNAERALLTLRAFDAMVRGENAQLIV
                     DLCERALIDGSPARGLGWTDSEWGFELPTMVGITYTFVDQLDRAESLFGEAVRAFEISG
                     WSGAHLAFAHTLLGMVHRRRGRLAEAEGFLREGLRLADRVGSGLPVHWDAACLLIDTLL
                     ARGRTEEARRIADRYDFGPPYPSAMVLPDAPCMRGRLLLAEGRKEEAIAELEAAGAALE
                     SRERFNGIWAPWAGDLARALAEDDPARAAHLAARNRVHAERFGTPTAMGEALRCVALFA
                     PPERAAQLLAEAVGHLEKSSSAYEHALARVEYGIAIGSHRELARAQKQAMACGAEGLAA
                     RAQQARASIRSSE"
     misc_feature    2140..2142
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     tRNA            4415..4488
                     /anticodon=(pos:7467787..7467789,aa:Pro,seq:ggg)
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /locus_tag="MWG59_RS34195"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /old_locus_tag="MWG59_34195"
                     /product="tRNA-Pro"
     gene            4415..4488
                     /locus_tag="MWG59_RS34195"
                     /old_locus_tag="MWG59_34195"
     gene            complement(4646..5614)
                     /locus_tag="MWG59_RS34200"
                     /old_locus_tag="MWG59_34200"
     CDS             complement(4646..5614)
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1026: transposase"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611377.1"
                     /locus_tag="MWG59_RS34200"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MWG59_34200"
                     /product="IS3 family transposase"
                     /protein_id="WP_248587340.1"
                     /transl_table=11
                     /translation="MKHCPAGFKADAVALYRSRPGATIKPVAGDLGVNTETLRNWIRAA
                     DGRRPGAHCAPTSAAQAGGHGVQAEPAAARIRKVHQDSDGTYGAPGITAELRDEGGQVV
                     NHKRVARIMRTIGLQGVRPRRRHRTTVGDQASPNAADLIGPDFTAAAVNTKYVGDITYL
                     PFNGAKPLYLATVIDLASRRLAGWAIADHMRTELVIDALAAAERTRGSLAGAVMHTDHG
                     SQYTSRAFAEISRSAGARQSMGAIGSSADNAAAESFDAAFKWETLKGRKGWSNEYEARL
                     DAFRWLTRYNTRRRHSRLGQRFPIAYENNFQATATTLVQAA"
     gene            complement(5541..5840)
                     /locus_tag="MWG59_RS34205"
                     /old_locus_tag="MWG59_34205"
     CDS             complement(5541..5840)
                     /EC_number="3.1.21.-"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0004519 - endonuclease activity [Evidence
                     IEA]"
                     /GO_process="GO:0009307 - DNA restriction-modification
                     system [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF016362.4"
                     /locus_tag="MWG59_RS34205"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MWG59_34205"
                     /product="restriction endonuclease"
                     /protein_id="WP_248586627.1"
                     /transl_table=11
                     /translation="MVAALLQRDGFNVLQRHGGAGDRGADVIAVAPTGEKLVAQCKLIT
                     GVNLCRGLDPGSWTPEDLDLDGPGERSPRGDEALSRRVQGGRSRVVPVEAGSDD"
     gene            <5855..6154
                     /locus_tag="MWG59_RS34210"
                     /old_locus_tag="MWG59_34210"
                     /pseudo=""
     CDS             <5855..6154
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010988951.1"
                     /locus_tag="MWG59_RS34210"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /old_locus_tag="MWG59_34210"
                     /product="transposase family protein"
                     /pseudo=""
                     /transl_table=11
                     /translation="HDLTAARTHGIGDALAEAGLKCWADKAYQGAGGSIRVPFRGRRRK
                     R"
     misc_feature    complement(6305..6320)
                     /note="TFBS match to CRP, Cyclic AMP receptor protein,
                     confidence: weak, score: 16.03"
                     /tool="antismash"
     misc_feature    complement(6320..6333)
                     /note="TFBS match to LexA_variant_2, Repressor of DNA
                     damage response, confidence: weak, score: 19.52"
                     /tool="antismash"
     gene            6414..6617
                     /locus_tag="MWG59_RS34215"
                     /old_locus_tag="MWG59_34215"
     CDS             6414..6617
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018487268.1"
                     /locus_tag="MWG59_RS34215"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MWG59_34215"
                     /product="hypothetical protein"
                     /protein_id="WP_097936644.1"
                     /transl_table=11
                     /translation="MPEFRQPGWTRGIAPLDESAGGQVFGGASPVAATPVVVAGAGAVV
                     IAFAAGVAARTLANGGNIELPM"
     gene            6908..7081
                     /locus_tag="MWG59_RS34220"
                     /old_locus_tag="MWG59_34220"
     CDS             6908..7081
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018487269.1"
                     /locus_tag="MWG59_RS34220"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MWG59_34220"
                     /product="hypothetical protein"
                     /protein_id="WP_248586628.1"
                     /transl_table=11
                     /translation="MSTASIPAVLSETGVLSESDPGRAPMDTVPVASVTFTMSACVGIS
                     VCLTGSTIELPQ"
     gene            7155..7349
                     /locus_tag="MWG59_RS34225"
                     /old_locus_tag="MWG59_34225"
     CDS             7155..7349
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003965561.1"
                     /locus_tag="MWG59_RS34225"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MWG59_34225"
                     /product="hypothetical protein"
                     /protein_id="WP_097936643.1"
                     /transl_table=11
                     /translation="MSKSSTPAALTATGALTESDPGVTLSGLAPVAATPVAIVACLGAA
                     FVAGYAAGRAAGSDIELPM"
     gene            7410..7613
                     /locus_tag="MWG59_RS34230"
                     /old_locus_tag="MWG59_34230"
     CDS             7410..7613
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003965562.1"
                     /locus_tag="MWG59_RS34230"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MWG59_34230"
                     /product="hypothetical protein"
                     /protein_id="WP_097936642.1"
                     /transl_table=11
                     /translation="MSTSPIPAALRGAGGLSESAPGQALSTFAPVAATPGIVAGAAVGV
                     ALVNAFVAGYNYTGNGNIELPM"
     gene            8046..10004
                     /locus_tag="MWG59_RS34235"
                     /old_locus_tag="MWG59_34235"
     CDS             8046..10004
                     /NRPS_PKS="Domain: Abhydrolase_1 (361-474). E-value:
                     1.4e-16. Score: 52.8. Matches aSDomain:
                     nrpspksdomains_MWG59_RS34235_Abhydrolase_1.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF00561"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Thioesterase"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1262: haloalkane dehalogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012378587.1"
                     /locus_tag="MWG59_RS34235"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MWG59_34235"
                     /product="alpha/beta fold hydrolase"
                     /protein_id="WP_248586629.1"
                     /sec_met_domain="PF00561 (E-value: 5.3e-12, bitscore: 44.7,
                     seeds: 48, tool: rule-based-clusters)"
                     /sec_met_domain="Thioesterase (E-value: 1.6e-07, bitscore:
                     30.5, seeds: 16, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPSRPTRPSGPRRQRPTLRGVLSALQGPAPLSREQAMGASERLAA
                     ATSLLSSIEHLARRREHRSSRLNEWAISRDAYARYGRPFRKLLDLASDERTNRALHAGR
                     VAASAALMLPGNGRWRGAATLYLGVSGALLYPAERYGTDGSDQASTMVQTMTGLARLAP
                     SSRTQDALIWYVALQGNLSYLISGWVKLLGPDWRSGAALAGVMRTRTYGHEGIWKLTHR
                     YPRSSRAAVYGVLGLECLFPVLYLKGGRLTRPVLGGAVLFHVANGYVMGLGRFLPAFAA
                     MHPMVAYTSTPRSHPAVAGRDDTMPATVALLAAGGAAVLGAAAVARRLRVTDTPHGGSV
                     VTTRHGNELSVQSTLTGRSTNPVVVFVHGLGACPAYFAWIVRALGGGDRQWLMYNRAGY
                     GPSRRRADGEYTLEESVDDLVDLIDAAVPEGRQVVLMGHSLGGEISRRAAVRLGSRVNS
                     VVYVDSSHPGQLTRSAQQGSTAPRIGEGLRTMAISLRLGFGALMRAPEPVADLPEEVRH
                     KVRMEFADSRVWTAAGREWKAVEQDFPSFTGPLDALDTHALVLSAQRTVDRDPDHLLMH
                     KDLADAHSGDRTVRSVVIEGADHDGILTDPQHAAETLRHLLAFLADTAGREPGARPGPL
                     TGTEPSGRTAASEEENR"
     aSDomain        9129..9467
                     /aSDomain="Abhydrolase_1"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_MWG59_RS34235_Abhydrolase_1.1"
                     /evalue="1.40E-16"
                     /label="MWG59_RS34235_Abhydrolase_1.1"
                     /locus_tag="MWG59_RS34235"
                     /protein_end="474"
                     /protein_start="361"
                     /score="52.8"
                     /tool="antismash"
                     /translation="PVVVFVHGLGACPAYFAWIVRALGGGDRQWLMYNRAGYGPSRRRA
                     DGEYTLEESVDDLVDLIDAAVPEGRQVVLMGHSLGGEISRRAAVRLGSRVNSVVYVDSS
                     HPGQLTRSA"
     gene            10001..10609
                     /locus_tag="MWG59_RS34240"
                     /old_locus_tag="MWG59_34240"
     CDS             10001..10609
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     linaridin: cypI"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003965564.1"
                     /locus_tag="MWG59_RS34240"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MWG59_34240"
                     /product="hypothetical protein"
                     /protein_id="WP_097937322.1"
                     /sec_met_domain="cypI (E-value: 1.2e-33, bitscore: 115.1,
                     seeds: 22, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSNPRLPRATGSLLTRAFGGTDGKVRLAAGVLFLGAICCQHPHPS
                     FDRVQRLDPLASIFPNWRFFAPTPAQHDFQFYYRTLDEAGETSDWSALEVIQGRRARQF
                     VWFPERRSEKAVYDLGSEILRVLDRGFEVAVTLPSFRILRNFFREEIERSGTPDVKGFQ
                     FALVQDSGYDEAEEPEIIFLSPYTPMRETAAPARESETV"
     gene            10606..11418
                     /locus_tag="MWG59_RS34245"
                     /old_locus_tag="MWG59_34245"
     CDS             10606..11418
                     /EC_number="2.1.-.-"
                     /GO_function="GO:0008168 - methyltransferase activity
                     [Evidence IEA]"
                     /GO_function="GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1248: methyltransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018487274.1"
                     /locus_tag="MWG59_RS34245"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MWG59_34245"
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="WP_097937321.1"
                     /transl_table=11
                     /translation="MSTAAPSWTSVATAPEVQDIGYGRVFADFYDRLLPHDGSAERTAE
                     VLASWHPGGGTLELGVGTGRVAVPLARLSGEVVGVDSSPEMLQRLCETVDATGAPVTPV
                     HGDIRTYADDSRYGLVYCVCATLSLICDPAEQRTAVARAARHLAPGGTLVVETHNPGFV
                     TALHEGRARTSFFVPYAEPGTGVQTYSTLIPGGLWHASHLVHEGGRVSIGTEITRLTTA
                     EDVDSYAADAGLVLVSRQGDWAGGPFLPEGSGVHISRYRRPASGEERS"
     gene            11415..13316
                     /locus_tag="MWG59_RS34250"
                     /old_locus_tag="MWG59_34250"
     CDS             11415..13316
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1288: ABC
                     transporter related protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012378589.1"
                     /locus_tag="MWG59_RS34250"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MWG59_34250"
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_248586630.1"
                     /transl_table=11
                     /translation="MTATAAASGGAVRNLTRGQWRLLLGGTALGLLGVVCTLAQPVLLA
                     DLIRAAGDHRPVVGVVVVLVVLFLLDAVLSAAQGCLIGRAGENIVRDARVLLSGKVLRA
                     DRAHLDTWRQGDLHTRLVGDTSLMKIALTQSLAQIVLNGLIVVGAVVMMAFTDIWLLLI
                     AVGCLGIAASGSVWLARALRRAALTNREDIGDFGADLQRVLTALTTVKAANAEGREQNR
                     LAESADRARVSGNRVTVLNAMFTPALNVGLQASLAAVMGIGMARVVAGSISLADFSAFT
                     MYLFYLVSPLVLVFLSIGTYLQGRAAVQRVDELDTLPQEDEHPAGTADPADGRPAAPAG
                     DSATRPAPQGGHPAVEFRDVFFGYGDRQVLEGVSFTVPAQGLTAVVGASGAGKTTVFQL
                     IERFYRPRGGAILLDGRDIAHLPSAEIRGRVGYVQQDNAAMRGTLRENIVYAAPDATEA
                     EIAEAVELAGLTEVVAELPDGLDTLLGDQGTGLSGGQRQRLCVARALLQKPDVMLLDEA
                     TAHLDSDAEAALRDSLRGISGRCAVVAIAHRISTVAEADRIVVLDEGRVRAVGTHTELL
                     GNDALYRRLAATQFADRPLGGRPAPDPVPGGAQGAVPGSGPVPEPVPAALPDAGAVR"
     gene            13337..>13435
                     /locus_tag="MWG59_RS39395"
                     /pseudo=""
     CDS             13337..>13435
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF024842.4"
                     /locus_tag="MWG59_RS39395"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /product="NAD(P)-binding protein"
                     /pseudo=""
                     /transl_table=11
                     /translation="MGGGPNGLAAAVTLARAGLRVAVYEAADTIGGG"
     gene            13923..14783
                     /locus_tag="MWG59_RS39400"
     CDS             13923..14783
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1222: dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="MWG59_RS39400"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="WP_349239604.1"
                     /transl_table=11
                     /translation="MAHGPGWPLPRGGSPRIAEAMADDIRAHGGELHTGRKITDLRELA
                     GARVVLLDIAPTALPGLAGGALPPGYTRWLSRYRYGPAAGKADFLVSGPIPWSAPETGR
                     AGTVHLGGTAAEVFRQETANARGREGGSPFVLVVDPAVTDPGREVAGRRPVWAYAHLPH
                     GSACDPLPVIRAAIERYAPGFTDSIVAQRGLSGRDYAAYNPNYVGGDIATGAIDLRQTV
                     FRPVPRWDPYRTPLPGVYLCSAATPPGPGVHGMCGLLAARSALRREFGRPLPVLRPVGA
                     GTPAA"
     gene            complement(14838..15851)
                     /locus_tag="MWG59_RS34260"
                     /old_locus_tag="MWG59_34260"
     CDS             complement(14838..15851)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003965568.1"
                     /locus_tag="MWG59_RS34260"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MWG59_34260"
                     /product="LuxR family transcriptional regulator"
                     /protein_id="WP_248586631.1"
                     /transl_table=11
                     /translation="MGTHTMSPLGLSSTEEAVYRFFLRNPGAAVRDARTAAPMDGEGVH
                     RAAERLRDRGLLHGSEARTWATDPGVVVARLAEEQLDAAYRTLRRLADPRPILRSLWRD
                     VPAPSFAGGGGVYAGSAIALDRLEDLGQALARIDRAAFHADAEILAAVPNRALVPLGTA
                     HTLSLGLRCLRRGVRVRTLVGSDAPTPPTGADQLRRLRSHGAEVRVAEGLSELVLVYDR
                     RTALVPVDAHDIDRGVLCIEESGPVSSLVTLFERLWAAATDLADRPASKPGTDSPTGTQ
                     RTVLLLMCTATKDEAGARAAGMSLRTYRRHVSDLLALLGACSRAQAALLARERGWV"
     gene            16351..17895
                     /locus_tag="MWG59_RS34265"
                     /old_locus_tag="MWG59_34265"
     CDS             16351..17895
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="MWG59_RS34265"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="MWG59_34265"
                     /product="hypothetical protein"
                     /protein_id="WP_248586632.1"
                     /transl_table=11
                     /translation="MVSRRSLLARPGWADTGVAVVETGPWPDARIGRLTAEARVTDARC
                     RELIVRLAAGNPLIADAACRAVHAGAPPTAAGAVADGAAREIVERLSRERPAGPWQHAL
                     VRLASVWSADEELLDADPDLFDTLAGLSPVVPTELGLALTEPFRGVIELAHRWRRPAAH
                     RGAWARALAHRKKLLAAEPAADRRSRLTEGIIALADDDAVRETMFPISVTRDVIHTATP
                     DDADTIGTLMRQWARQGGLDVRWTDRLVERWLVDDPASFQLVRDGGDRIIGLTNTQQVT
                     ERTMNCVEPLLQQHTDRLLGRPRGAGGWLLGAAYCPDRGAHAHLLRGLLRQVITGGLLL
                     TVSTPNPDYQRLLRGLRFQRHGTTTDDVYRCGRKPEIFSQDFGSAALPDWTERLARSSG
                     ARGGPRPTGQEVARALAVIADPARLAESPLLSSPRPRTVAELRADLWEAVRRLADSEVR
                     EEAEAGWILQHYYLGRPRTHQRLAQQLHISRATYFRRLRHGLDLVGGGLAAERSVP"
     gene            complement(<18013..18639)
                     /locus_tag="MWG59_RS34270"
                     /old_locus_tag="MWG59_34270"
                     /pseudo=""
     CDS             complement(<18013..18639)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008745670.1"
                     /locus_tag="MWG59_RS34270"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /old_locus_tag="MWG59_34270"
                     /product="transposase family protein"
                     /pseudo=""
                     /transl_table=11
                     /translation="MTGVITTS"
     misc_feature    complement(18460..18462)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            18832..19668
                     /locus_tag="MWG59_RS34275"
                     /old_locus_tag="MWG59_34275"
     CDS             18832..19668
                     /GO_function="GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Abhydrolase_6"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1262: haloalkane dehalogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012381111.1"
                     /locus_tag="MWG59_RS34275"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MWG59_34275"
                     /product="alpha/beta hydrolase"
                     /protein_id="WP_097937336.1"
                     /sec_met_domain="Abhydrolase_6 (E-value: 2.3e-16, bitscore:
                     59.9, seeds: 455, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MATAREQSARVEDRVASADGTEIAFEQSGRGPAVVLVASALADRS
                     DTTKLAALLAQHFTVINYDRRGRGASGDANAYAPDREIEDIAALVEHVGGSASLFGSSS
                     GAVLALRAAAAGVNVDRLALYDPPFVVAEGDDGPPKDLAQQITVLLAEGRRSDAVKYFM
                     TRVQGMPGIAVFFMKLMPKMWANLTKLAGTLPYDIAVMGDTQQGKPLDAEEWKGVAVRT
                     RVLTGGKSPAAFQRAALAVTEILPQADHRTLPGLNHGAVVMAPRKIAPQIIEFIKG"
     assembly_gap    19957..19966
                     /estimated_length=10
                     /gap_type="within scaffold"
                     /linkage_evidence="paired-ends"
ORIGIN
        1 aggactccgc gtcgtcccgg cccggtgtcc gcgtaccggc gtcgagcccg tccgcgtacc
       61 gctccagcag gccgttcggg tccttgccgc ccgctcccgc gacccggaag ccggccgcca
      121 ggaacgtacg cgcgtacccc tccagtccgt cggagcggac acccgagtga gacggggggc
      181 cgggcaggtc gagccgggcg ccgcccggcg tggcccactt ccacgcggcg gccagcatcc
      241 cgtcggctgc cgcctcccag tgggcacggg tgtaaccggt gtacgggctc gacgtgcggt
      301 cttccggggg gagtccgaaa agggcaccag gggaggcggt catgcgggaa tcctgagcga
      361 ctgatcaaag agggtcaata gatcgatcac aagagggctg aatcgatcaa acgctcattg
      421 ggcgggtggt gcgtgatggg tgaggtgagg gtctcgcgtc cgtcggccgg aaaccggtgc
      481 gcctaccgat ccttcccgac gcggatatct gaggccgcca tgccgccgtg ccgccgcctc
      541 agggaagcag cagccagtcc gctcccacgg cggccagcag tcccgccccc agcagccagc
      601 tggccagcct ggtgcgaccg ttcctgctca gctcgatcac cacgccgcac aggatgagcg
      661 cgagcccgta gacgccgacc acgagcaccg acgagcggct cgcgatgcgc agcccgagca
      721 cgagggccat cgccgccatg cccaccgagg agagtgcgat ccgcagccgc cgggcctggc
      781 gcggggtgag tctcttcccg tcctggctgt cctggccgtc cccacggtcc tcaccgccgg
      841 atccatcgac tccatccgtc tccgtccccg ccgccgctac cgtctccgcc gccaccgtct
      901 tcgtctccgt ggcggtgtcg gctatcgggg tgtcggcgcc ccggtcccgt tcctggtccc
      961 ggtcgggctc ctcgtcgttc agcccgtcct cgcgctggtc ccggtgctgg tcctggtcag
     1021 aagtgctcat ggagccggat cgtagtagct gtacggtgcc agggtccgcg gacccggatc
     1081 ttccgctccc gctccgggcc cgcggggccc ggtcttcggg ctacgcccgc aggcggggcg
     1141 cctcggccgc cgcgtcgacc gtcgggcccg actccacccg gtccgccaac tcccgcgccc
     1201 agtcgcacag tccggagacc gcgatcccgt gcggcccgga cccggtgaac ggggtgagcg
     1261 cccccgcgcc ccggcgcagc agccgggccc cgccctcggt gttgccccgc gcggaatggg
     1321 tcagccccac cgcgagctgg gccagccccc gccagagctc gcgttcgtcc tcggggcccg
     1381 acttccaggc gtcctcgaag acctcgtgcg cgtggaacgg catccccgcg tccagcagcc
     1441 gctgcgcctc ccggagcgtc tccgcaggcg tgcggacgac cccctccggc tgtcgttcga
     1501 cgccgggtgt cccgtacggc agggggcgtc ccagcccgtc acgggggcgc gcgttgcgcg
     1561 cccggccctc ggcatcacgg tctctgcgcg tctcgttcac tactcgattg tgccccgcac
     1621 ctgcggagaa tcgtgcgaac actgtcggcg agcacccgcg cacgactagg ctcgaccgtc
     1681 gagaagactg cctctgtggg aagggtgggc atgaagccgt cccggccgtt gtacgagcgt
     1741 gaaccggaac tcgccgccgc tgcggaggcg gtggacgccc tgtgcggtgc gcaggccgtc
     1801 ggcggactcc tggtattcag cggagaggcg gggatcggca agaccgcact gctcgcggag
     1861 atccggagga tggccgccga ccgttgcacc gtctggtccg cccggggagg cgagaccgtc
     1921 acctccgtac cgttccacgt cgtccggcag ttgctgcagc cagcactcga ccagttcccg
     1981 cccgacgaga cccgcgccct gttcggcgac tggtacgaga cgaccgcccc ggccctggga
     2041 ctcgccgagc cgagcggtcc gcagcccgac ccgcagggtg tccgtgacgg tttggacttc
     2101 gtcgtcggtc ggctcgcgtc ccggctcagc caccggccgt tactgctgat cgtggacgac
     2161 gcgcactggg cggacggcga atccctcgcc tggctggcct cgttcaccgc ccgcctcgga
     2221 gagctgccgg tcctggtggt gcaggcccac cgcccgcagg agctggccga gcgcgacgcc
     2281 aactacatcg ccgaccgtga ggccgagcgc ggcttcggca gcaagggcac ggtgacccgg
     2341 gtcgccctgc gggccctgac cccggacgcc accgccgtac tggtccgcgc gggcctcggt
     2401 gatcacgccg acgacccgtt ctgccgcgag gtgtgggccg tcaccggagg caacccgtac
     2461 gaggcggtcg agctggtcgc caaggtccag gaccgcgaac tgccgccggt ggaggaatcc
     2521 gcgggcgaac tgcgcgagct cggcgcgtcc gcaaggggca gcgggctcgt cgcccggctg
     2581 gagcggctcg gcaccaacgc caaccggttc gcctgggccg ccgcggtgct cggcaccgac
     2641 atctcgcagg aactggccgc cacactcgcc ggaatgagct cggcggaggc agccgactgc
     2701 acggcccggc tgcgcgacgc ccgtatcgtc agcggcttcg acccgctgga gttcgtccac
     2761 ccgctgatcg cgacggcggt ctaccgctcg atcccgccgg ccacccgcac cgccatgcac
     2821 ggacgcgccg cctgggcgat cacccgggcc ggtctcggtg ccgccgcagc atcccggcac
     2881 ctgctggagg tccacccgga cgacgaccag gaactggtcg cgcaactgcg cgaagccgcc
     2941 ggccagcacc tcgccgtcgg tgcgcccgaa gcggcccggc gctgcctgga acgggcgatc
     3001 gaggagccgc cgcgccccaa ggaccgggcc gtcctgctgt acgagctggg ctgcgcgacg
     3061 ctgctgagct ccccgcccac cacggtccag cacctgcgcg ccgccctgga catgccgggg
     3121 ctcgacgacg ggctgcgggt cgacgccacc ttccggctcg ccgcagcgct cgcccacaac
     3181 aaccagctca aggacgcggc gctctcgctg gccgccgagg ccgcacgcac cgcacccggc
     3241 cccgggctga tgcgtctgca ggccgcgcac ttcatgtggg agggcatgca ggccgtcgag
     3301 gacgacgggc ccgcccgctc ccggcggctc acccgcaacg ccgaccacct gaagggccgc
     3361 gacaacgccg agcgggcgct gctcacgctg cgggccttcg acgccatggt gcgcggtgag
     3421 aacgcccagc tcatcgtgga cctgtgcgaa cgcgccctga tcgacggcag cccggcccgc
     3481 ggcctcggct ggaccgactc cgagtggggc ttcgaactcc ccaccatggt cggcatcacc
     3541 tacaccttcg tcgaccagct ggaccgcgcg gagagcctct tcggcgaagc ggtccgggcc
     3601 ttcgagatct ccggctggag cggggcccac ctggcgttcg cccacaccct gctcggcatg
     3661 gtccaccgcc gtcgcggccg cctcgccgag gccgagggct tcctgcgcga agggctccgc
     3721 ctcgccgacc gcgtcggttc cggactcccc gtgcactggg acgcggcctg cctcctcatc
     3781 gacaccctgc tggcccgcgg acgcaccgag gaggcccgcc gcatcgccga ccgctacgac
     3841 ttcggcccgc cctaccccag cgccatggtg ctgcccgacg caccgtgcat gcggggccgc
     3901 ctgctgctgg cggagggccg caaggaggaa gcgatcgccg agctcgaagc ggcgggcgcc
     3961 gctctggagt cgcgcgaacg cttcaacggc atctgggctc cctgggccgg cgacctggcg
     4021 cgggccctgg ccgaggacga cccggcccgc gcggcccatc tcgcagcccg gaaccgggtg
     4081 cacgccgaac ggttcggcac gcccaccgcc atgggcgagg cactgcgctg cgtcgccctc
     4141 ttcgcgcccc cggagcgggc cgcgcagctg ctcgccgagg cggtgggcca cctggagaag
     4201 tcctcctccg cctacgagca cgccctcgcc cgggtcgagt acggcatcgc gatcggctcg
     4261 caccgggagc tcgcccgcgc ccagaaacag gcgatggcct gcggagccga agggctggcc
     4321 gcccgcgccc aacaggcaag ggcgtcgata cggtcctccg agtgaggtaa tgtttgtcct
     4381 gcgcggtcac ccggggaaac cgggggaaac gcgacgggac gtggcgcagc ttggtagcgc
     4441 acttgactgg gggtcaaggg gtcgcaggtt caaatcctgt cgtcccgact ggagacagtc
     4501 gcagatcagg gccggtttcg gagcaatccg aaaccggccc ttgatcattt ccggggacca
     4561 gttggggacc agttgggggc cggcgtcctt gaccgggtca gcgggtcatg acgacggggg
     4621 ccttggcccc ggattctgaa cacgtctatg cggcttggac cagcgtagtt gctgttgctt
     4681 ggaagttgtt ctcgtaggcg atcgggaacc gctgaccgag gcgggagtgc cggcgtcggg
     4741 tgttgtatcg ggtcagccag cggaaggcgt cgagtcgtgc ctcatactca ttcgaccagc
     4801 ctttgcggcc cttgagtgtc tcccacttga aggcggcgtc gaagctttcc gcggcagcgt
     4861 tgtccgcgct ggacccgatc gcccccatgc tctgccgggc ccctgctgac ctggagattt
     4921 cagcgaaggc cctgctcgta tattgcgagc cgtgatcggt gtgcatcacc gcaccggcca
     4981 ggctcccgcg ggtccgctcg gcggccgcga gggcgtcgat gacgagctcg gttcgcatgt
     5041 gatcggcgat ggcccacccg gccagccgtc gtgaggcgag atcgatgacg gtcgcgagat
     5101 aaagcggttt cgcgccgttg aacggcaggt atgtgatgtc gccgacgtac ttcgtgttca
     5161 ccgcggccgc ggtgaagtca gggccgatca ggtccgccgc attcggcgac gcctggtccc
     5221 cgacggtggt gcggtgtcgg cgtcggggac ggaccccctg gagcccgatg gtccgcatga
     5281 tcctggcgac ccgcttgtgg ttgaccacct ggccgccctc gtcacggagc tcggcggtga
     5341 tcccgggggc tccgtaagtg ccgtcggagt cctggtggac cttgcgtatc cgggctgcgg
     5401 ccggctctgc ctgaacaccg tggccgccgg cctgcgcagc ggacgtcggt gcgcagtggg
     5461 cgccggggcg gcgcccgtcg gcggcccgga tccagttccg cagtgtctcg gtgttcaccc
     5521 cgagatcacc ggcgaccggc ttaatcgtcg ctcccggcct cgaccggtac aacgcgactg
     5581 cgtccgcctt gaacccggcg ggacagtgct tcatccccac ggggactccg ttctcctgga
     5641 ccatcaagat ccaagtcctc cggtgtccaa gatccggggt caaggcccct gcagagattc
     5701 acccccgtga tgagcttgca ctgcgcgacc agcttctcgc cggtgggcgc gaccgctatg
     5761 acgtcggcgc cgcggtcgcc tgctccgccg tgtctttgca ggacgttgaa tccgtcgcgt
     5821 tggagcaggg cggcgaccat ctcctcgaac ccgtcacgac ctgaccgccg cccgtaccca
     5881 cggcatcggc gacgcactcg ccgaggccgg actgaagtgc tgggccgaca aggcttatca
     5941 gggcgctggc ggttccatcc gggtgccctt ccgcggccgt cgccgcaagc ggtagcgcag
     6001 gcacaacagc acccacgcca agatccgctg cctcggcgag caggccatgg ccacccccaa
     6061 aggctggcgg ctcctgcgga agctccgccg tggcaccaac cgcatccccg acctggtgaa
     6121 ggcagtcctc gcgcttcacc acgcatcagc gtgaggttgg aaaaggctca cgcgttccag
     6181 gacgcattaa cggaatcggt acgcgccgca tacccccgtg cccgaacccg caggatgttg
     6241 cttcggagtc cgcatcctca tgccagcgga gtggtcttcc ctttccgccg ggctctcggc
     6301 atcgtgtgga gcgcatcaca gaacgtctgt tcacgcgggg tccgggtccc gggtgcgctt
     6361 gcgcgcgcct ggatgagggc gccccggtga cggcccaccc atgaaggaga aacatgcccg
     6421 aattcagaca gcccggttgg accaggggca tcgccccgct cgacgagagc gccggtgggc
     6481 aggtgttcgg gggcgcgtcc ccggtcgccg cgaccccggt cgtcgtggcc ggcgcgggtg
     6541 ccgtggtgat cgccttcgcg gccggcgtag ccgcccgcac gttggccaat ggtggcaaca
     6601 tcgagctccc gatgtaggcg gtggtacccc gccacccgta tcggccgggg aagtcgcccg
     6661 gcgcgtggcc cggacaccct ccgctcccac cggggaggcc cgtcccgccc cctcccgtcg
     6721 gagctgtgtc ccgtcagggg ccgtcggcgt cggttgccgt acccatgacg gctccacgac
     6781 gcgaaggccg tccgacggcc gggtacgcgg ccgacggcac tcggcgcccc gacctgtggg
     6841 tccgtcccgt ctgcgccgcc cgcccatgac gtcaccccac cggccgccca ccagcgagga
     6901 gaagtccttg agtaccgctt cgataccggc cgttctgtcc gagaccggtg tcctgtccga
     6961 gtccgacccc ggccgggcgc cgatggacac cgttccggtc gcatccgtca cgttcaccat
     7021 gtcggcctgc gtcggcatct cggtctgcct caccggaagc accatagagc tcccgcagta
     7081 ggcccgacgg gccgcccgtt gcgggtggcc cggcacctca cccgtacccg ccacctcatc
     7141 agtaggagag tttcatgagt aagtcctcta ctccggccgc cctgaccgcg accggtgccc
     7201 tgaccgagtc cgaccccggc gtgacgctgt cgggcctcgc gccggtcgcc gcaaccccgg
     7261 tggccatcgt ggcctgcctg ggagccgcgt tcgtcgccgg ttacgcggcc ggccgcgcgg
     7321 ccgggagtga catcgaactc ccgatgtagc cgtgtttccc ccagcaccgg accgttccgt
     7381 tccatcactc cagtgaggag aacaaccctg tgagcacgtc tccgataccg gccgccctgc
     7441 gcggcgccgg cggtctgtcc gagtccgccc ccggccaagc gctgtcgacc ttcgcgccgg
     7501 tcgccgcgac ccccgggatc gtggccggcg cggccgtcgg cgtcgccctg gtgaacgcct
     7561 tcgtcgccgg ttacaactac accggcaacg gcaacatcga gctcccgatg tgagttcgct
     7621 acgccgtccc cgtccccggc gggggcgccc cgtgaacgcg gcgacgcccc agggggcggt
     7681 gagccgcctc cgcggcacgg gcgccgagcg gtaggtccgt cgcccccggc cccggcacgg
     7741 ggagccgcgg ccgccgtgcc ggggcttagc cggaagcgac ggtgcgtggg tgacgtgggg
     7801 acgagcgcct ccagggcggt cgcccgccca tgccaccacc acgcccggac gcacggcccg
     7861 gccccggcac gagcccggcc ctgcaggaac ccgtcccgta cgacccggta cgcccccgga
     7921 cagcaccctg cccggcccac ccggcccgtg ggaccccgta ccggcccggg aaccgcccgc
     7981 caccctccgc cttgtcaccc cgccgccctc ccgcctcgtt cgtccccagc acggaaggcc
     8041 cgtccatgcc ctcacgcccc acccgaccga gtggaccccg cagacagcgg ccgacgctgc
     8101 gcggggtcct gtccgccctg caaggccccg cccccctctc ccgcgagcaa gccatgggcg
     8161 cctccgagcg gctggcggcg gcgacgtccc tgctgtccag catcgagcac ctcgcgcgcc
     8221 gccgggagca ccggtcgagc cgactgaacg aatgggccat ctcccgcgac gcgtacgccc
     8281 gttacggcag gcccttccgc aagctgctgg acctggcctc cgacgagcgg accaaccggg
     8341 cgctgcacgc cgggcgggtg gccgcgagcg cggccctcat gctgcccggc aacggccggt
     8401 ggcgcggggc cgccaccctc tacctcggcg tcagcggggc gttgctctac ccggccgagc
     8461 gctacggcac cgacggctcc gaccaggcgt ccaccatggt gcagaccatg accgggctgg
     8521 caagactcgc cccctcgtcc cgcacccagg acgccctgat ctggtatgtg gcgctccagg
     8581 ggaacctgtc ctacctgatc tccggctggg tcaagctgct gggtcccgac tggcggtcgg
     8641 gggccgcgct ggcgggggtg atgcggacca ggacgtacgg gcacgagggg atctggaagc
     8701 tgacccatcg ctacccgcgc tcgagccgcg ccgccgtcta cggtgtgctg ggcctggagt
     8761 gcctgttccc ggtgctctat ctgaagggcg gccggctgac ccgcccggtg ctgggcggcg
     8821 ccgtcctctt ccacgtggcc aacggctacg tcatgggcct cggcaggttc ctcccggcct
     8881 tcgccgcgat gcacccgatg gtcgcctaca ccagcacgcc gcgcagccac cccgcggtgg
     8941 cgggccgcga cgacaccatg ccggccacgg tggccctgct ggcggcgggc ggcgcggccg
     9001 tactgggtgc ggccgcagtg gcccgccggc tgcgcgtcac cgacaccccg cacggcggct
     9061 ccgtcgtcac cacgcggcac ggcaacgaac tgagcgtgca gagcaccctc acgggccgga
     9121 gtacaaaccc ggtggtggtc ttcgtccacg gactgggcgc ctgccccgcg tacttcgcct
     9181 ggatcgtccg cgctctcggc ggcggggacc ggcagtggct gatgtacaac agggccggtt
     9241 acggccccag ccggcgccgc gcggacggag aatacacgct ggaggagtcg gtcgacgacc
     9301 tggtggacct gatcgacgcg gcggtccccg aggggcgcca ggtggtgctg atgggccact
     9361 ccctgggcgg cgagatctcc cgccgcgcgg cggtcaggct gggctcccgg gtgaactccg
     9421 tcgtctacgt ggacagttcg caccccggcc agctcacccg gtcggcgcag cagggctcga
     9481 ccgcgccgcg gatcggggag ggcctgcgca ccatggccat cagcctgcgg ctggggttcg
     9541 gggcgctgat gcgggcgccc gagccggtcg ccgacctgcc cgaagaggtg cggcacaagg
     9601 tcaggatgga attcgcggac tcccgcgtgt ggaccgccgc ggggcgtgag tggaaggccg
     9661 tcgagcagga cttcccctcc ttcaccgggc cactcgacgc cctggacacc cacgccctgg
     9721 tgctctccgc ccagcggacg gtggaccgcg accccgacca cctgctgatg cacaaggacc
     9781 tcgccgacgc ccacagcggg gaccggaccg tccgaagcgt cgtcatcgag ggcgccgacc
     9841 acgacggcat cctcacggac ccccagcacg ccgccgagac gctccgccac ctgctggcct
     9901 tcctggccga caccgccggc cgggaaccgg gggcccggcc cggacccctg accgggacgg
     9961 agccgtccgg ccggaccgcc gcgtctgagg aggagaaccg atgagcaacc cccgtctccc
    10021 gcgcgccacg ggctcgctgt tgacccgcgc cttcggcggc acggacggca aggtccgcct
    10081 cgcggccggc gtcctcttcc tcggcgccat ctgctgccag cacccgcacc cgtccttcga
    10141 ccgggtccag cggctcgacc cgctcgccag catcttcccc aactggcgct tcttcgcccc
    10201 gactccggcc cagcacgact tccagttcta ctaccgcacc ctcgacgagg cgggcgagac
    10261 ctccgactgg tccgcgctgg aggtcatcca gggccgccgc gcccgccagt tcgtctggtt
    10321 ccccgaacgg cgcagcgaga aggcggtgta cgacctgggc agcgagatcc tgcgcgtcct
    10381 cgaccgcggg ttcgaggtgg ccgtgaccct gccctccttc cgtatcctgc gcaacttctt
    10441 ccgcgaggag atcgagcggt ccggcacgcc ggacgtcaag ggcttccagt tcgccctggt
    10501 ccaggactcg ggctacgacg aggccgagga gcccgagatc atcttcctct ccccctacac
    10561 accgatgcgc gagaccgcgg caccggcgcg agaaagcgag accgtatgag caccgccgcc
    10621 ccctcctgga cctccgtggc gaccgccccc gaggtccagg acatcggcta cggaagggtg
    10681 ttcgccgact tctacgaccg tctgctgccc cacgacggct ccgccgaacg caccgccgag
    10741 gtcctcgcct cctggcaccc cggcggcggc accctcgaac tcggcgtggg caccggacgc
    10801 gtcgccgtcc cgcttgcccg gctctccggc gaggtcgtcg gtgtggactc ctcgccggag
    10861 atgctccagc ggctgtgcga aaccgtcgac gccaccggcg ccccggtcac cccggtgcac
    10921 ggtgacatcc gcacctacgc cgacgactcc cggtacgggt tggtctactg cgtctgcgcc
    10981 accctctcac tgatctgcga cccggcggag cagcggacgg ccgtcgcgcg cgcggcgcgg
    11041 cacctggcac ccggcggcac cctcgtcgtg gagacccaca accccggctt cgtgaccgcc
    11101 ctgcacgagg ggcgcgcccg cacctccttc ttcgttccct acgccgaacc gggcaccggc
    11161 gtgcagacct actccaccct gatccccggc gggctctggc acgcctcgca cctggtgcac
    11221 gagggcggcc gggtgagtat cggcaccgag atcacccggc tcaccaccgc cgaggacgtc
    11281 gactcctacg ccgccgacgc cggtctcgtc ctggtgtccc ggcagggcga ctgggcgggc
    11341 ggcccgttcc tgcccgaggg gagcggcgtc cacatcagtc gctaccgccg ccccgcctcc
    11401 ggtgaggaac ggtcatgacg gccaccgcgg cggcgtccgg cggcgccgtg cggaacctga
    11461 cgcgcgggca gtggcggttg ctgctcgggg gcaccgccct cggactgctg ggcgtggtgt
    11521 gcaccctggc gcagccggtg ctgctggccg acctgatcag agccgccggg gaccaccgcc
    11581 cggtggtcgg ggtcgtcgta gtgctggtcg tgctgttcct gctggacgcc gtgctctccg
    11641 ccgcccaggg ctgtctcatc ggcagggcgg gggagaacat cgtccgcgac gcccgggtcc
    11701 tgctctcggg caaggtgctc cgggccgacc gcgcgcacct cgacacctgg cgccagggcg
    11761 acctgcacac ccggctggtc ggcgacacct ccctgatgaa gatcgcgctc acccagagcc
    11821 tcgcccagat cgtcctcaac gggctgatcg tggtcggtgc cgtcgtgatg atggcgttca
    11881 ccgatatctg gctgcttctg atcgccgtcg gatgcctcgg tatcgccgcg tccgggtcgg
    11941 tgtggctggc ccgcgcgctg cgccgggccg ccctgaccaa ccgggaggac atcggcgact
    12001 tcggcgccga cctgcagcgc gtgctcaccg ccctgacgac ggtgaaggcc gccaacgccg
    12061 agggccgtga gcagaaccgc ctggcggagt ccgccgaccg cgcccgcgtc tccggcaacc
    12121 gggtcaccgt gctgaacgcc atgttcacac ccgcgctgaa tgtcggtctc caggcgtcgc
    12181 tcgccgccgt gatgggcatc ggcatggccc gcgtcgtcgc cggctccatc agcctggccg
    12241 acttctcggc cttcacgatg tacctgttct acctggtgtc gccgctggtc ctggtcttcc
    12301 tctcgatcgg cacctacctc cagggccggg cagccgtcca gcgcgtggac gaactcgaca
    12361 ccctgccgca ggaggacgag cacccggccg gcaccgcgga cccggccgac ggccggcccg
    12421 ccgcccctgc cggcgactcg gccacccgtc cggccccgca gggcggacac cccgcagtgg
    12481 agttccgcga cgtcttcttc ggctacggcg accgacaggt gctggaaggc gtgtcgttca
    12541 ccgtccccgc ccaagggctc accgccgtgg tgggtgcctc cggcgcgggc aagaccaccg
    12601 tcttccagct catcgagcgc ttctaccggc cccggggcgg cgcgatcctc ctcgacggca
    12661 gggacatcgc ccacctcccg tccgccgaga tccgcggccg ggtcggctac gtccagcagg
    12721 acaacgccgc gatgcgcgga accctccgcg agaacatcgt gtacgccgcg cccgacgcca
    12781 ccgaggcgga gatcgccgag gcggtcgaac tcgccggtct caccgaggtg gtggcggagc
    12841 tgccggacgg cctcgacacc ctcctcggcg accagggcac cggactctcc ggcggtcagc
    12901 ggcaacggct ctgcgtggca cgggcgttgc tccagaagcc cgacgtgatg ctgctcgacg
    12961 aggccaccgc gcacctggac tccgacgccg aggcggcgct gcgcgacagc ctgcgcggca
    13021 tctccgggcg gtgcgccgtc gtcgccatcg cccaccggat ctccacggtg gccgaggccg
    13081 accggatcgt ggtcctggac gagggccggg tgcgcgccgt gggcacgcac accgaactcc
    13141 tcggcaacga cgccctctac cggcggctgg ccgccaccca gttcgccgac cgccccctcg
    13201 gcggacgccc cgcgccggac cccgtaccgg gcggggccca gggcgcggtg ccgggctccg
    13261 gtccggtgcc cgagccggtc ccggccgccc tgccggacgc gggagccgtc cggtgagcac
    13321 agtggacgcg gcggtcgtgg gcggcgggcc gaacgggctg gccgccgcgg tcaccctggc
    13381 ccgcgccggc ctgcgggtgg ccgtgtacga ggccgccgac acgatcggcg ggggactgcg
    13441 cggcgccgcg ctgttcgact ccgaggtggt gcacgacatc tgcgcggccg tccacccctt
    13501 ggcggtggcc tcgccgttct tccgggagtt cgacctcgcg ggacggggcg tgcggatgct
    13561 gcggcccgac gtcagctacg cccatccgct ggacggcgac cgggtggccc tcgcccacca
    13621 cgacctggac gccacctgcg cgggcctcgg cccggacggg ccgcgctggc ggcggctgat
    13681 ggaaccgctg ctgacacaca gcgacgccat ggtcgacctg ctgctgtccg atctgcgcag
    13741 cccgcgcggg ctgcgcgccg cacccgctgt actgagccgg gtcctgctcc acgggacccg
    13801 gctcggctcc cgcactttcc gcggcgaggc ggcgcccgca ctgctcgccg gggccgccgc
    13861 gcacgtcgtc ggcccgctgc cctcgctgcc cggcagccgg cgtcgggctg ctgctggccc
    13921 agttggccca tggccccggc tggccgctgc cgcgcggcgg cagcccgcgc atcgccgagg
    13981 ccatggccga cgacatccgg gcgcacggag gggaactgca taccgggcgg aagatcaccg
    14041 acctgcggga actggcgggg gcgcgggtcg ttctgctgga catcgcgccg accgcgctgc
    14101 ccggcctcgc cgggggcgcc ctgccgcccg gctacacccg gtggctgtcc cggtaccggt
    14161 acggcccggc cgcgggcaag gcggacttcc tggtctccgg accgatcccg tggtcggccc
    14221 cggagaccgg tcgcgcgggc accgtgcacc tgggcggcac ggcggccgag gtcttccgcc
    14281 aggagaccgc caacgcccgc ggccgggagg ggggttcacc gttcgtcctg gtcgtcgacc
    14341 cggccgtgac cgacccgggg cgcgaggtgg ccgggcgtcg cccggtgtgg gcgtacgccc
    14401 atctgccgca cggcagcgcg tgcgacccgc tgccagtgat ccgcgcggcc atcgagcggt
    14461 acgcgccggg cttcaccgac tccatcgtcg cccaacgcgg gctgtccggg cgggactacg
    14521 ccgcctacaa ccccaactac gtaggtggcg acatcgcgac cggggcgatc gacctgcggc
    14581 agaccgtgtt ccggcccgtc ccccggtggg acccctaccg gaccccgctg cccggtgtct
    14641 acctctgctc ggcggccacc ccgcccggac ccggggtgca cggcatgtgc ggccttctcg
    14701 cggcccggtc ggcgctgcgc cgcgagttcg gacggccgtt gcccgtgctc cgcccggtcg
    14761 gcgcgggaac cccggccgca tgacgacccg ggccgggcgg gctggcgcca ccccggcccc
    14821 ggtccgcggg cccggggtca cacccagccg cgttcgcgcg ccagcagcgc cgcctgggcc
    14881 ctgctgcacg cgcccagcag ggccagcaga tcggagacat ggcgccggta ggtgcgcagc
    14941 gacatgcccg ccgcccgggc gcccgcctcg tccttggtgg cggtgcacat gaggagcagc
    15001 accgtgcgct gggtcccggt ggggctgtcg gtgcccggtt tcgacgccgg acggtcggcg
    15061 aggtccgtcg ccgccgccca caacctctcg aagagggtga cgagactgct caccgggccg
    15121 ctctcctcga tgcacagcac gccccggtcg atgtcgtgcg cgtcgacggg gaccagcgcg
    15181 gtgcgccggt cgtagaccag caccagttcc gagagccctt ccgcgaccct gacctccgca
    15241 ccgtgggagc gcagccgccg cagctggtcc gcgccggtcg ggggcgtcgg agcatcgctc
    15301 cccaccaggg tccgcacccg gacgccgcgc cgcaggcagc gcaggccgag tgagagagtg
    15361 tgggccgtgc ccagcggtac cagggcccgg ttgggcaccg ccgccaggat ctcggcgtcg
    15421 gcgtggaagg ccgcccggtc gatccgggcg agggcctgcc ccaggtcctc caggcggtcc
    15481 agggcgatcg cggaacccgc gtagacgccc ccgccgcccg cgaaggaggg ggcgggcacg
    15541 tcccgccaca gggagcgcag gatcggccgc gggtcggcga ggcggcgcag cgtccggtag
    15601 gcggcgtcca actgctcctc cgccagccgc gccaccacga cacccgggtc cgtggcccag
    15661 gtccgcgcct cgctcccgtg cagcagcccc cggtcgcgca gccgttccgc ggcccggtgc
    15721 acgccctccc cgtccatcgg tgcggcggtg cgcgcgtcac ggacggcggc gcccggattc
    15781 cgcaggaaaa accggtacac cgcttcttcg gtgctgctca gaccgagtgg cgacatcgta
    15841 tgggtcccca tggcccttcc cttgaacatg tccggcggga cgacggagcc caagtctgcc
    15901 cggtgagacc ggtcgtgagg tctcagcgaa gtctcacgcc ccgctggtac cagggaagtt
    15961 ccggatgcgt gaccacttga atgaacgggc tctgatcgct atgacagggg gccgtgcacc
    16021 gaagtgatcc tggaggtccg atggccgagg cacccgcagc cgcagcgccg gtacgagcca
    16081 cgccgaactc cctgcgggag gtggtggcaa gccgtgatct ggccaatctc accggcccgc
    16141 tcggcagcgg gaagtcccgg ttagtcgccc gactcgggcc cgtctccctc cttgacctcg
    16201 accggcccgg cgccctggag cggctgccga ccgcgctcgc cgaggacacc ccggctccgc
    16261 tggtcgtgga cagcgccgac gacgaccgcg ccctggccgc gctggagccg ctgcggctgc
    16321 gcccgcccgg cagcggctta gcctgtcctc gtggtcagca ggcgctccct gctggcccgg
    16381 ccgggatggg ccgacacggg ggtcgcggtc gtggagaccg gcccgtggcc ggacgcgcgg
    16441 atcgggcgtc tgacggcgga ggcgcgggtg accgacgcgc ggtgccggga actgatcgtc
    16501 cggctcgccg cgggcaaccc gctgatcgcc gacgcggcct gccgggccgt ccacgcgggt
    16561 gcgccgccga ccgcggccgg ggcggtggcc gacggcgccg cccgggagat cgtggagcgg
    16621 ctctcccggg agcggcccgc cgggccgtgg cagcacgccc tggtccggct ggcctccgtg
    16681 tggtcggcgg acgaggaact gctcgacgcc gacccggacc tgttcgacac cctggcgggg
    16741 ctcagcccgg tcgtccccac cgaactcggg ttggccctca ccgagccctt ccggggggtg
    16801 atcgaactgg cccatcgctg gcgtcggccc gccgcccacc gcggcgcgtg ggcccgcgcg
    16861 ctggcgcacc gcaagaagct gctggccgcc gagcccgccg ccgaccgccg tagccgtctc
    16921 accgagggga tcatcgctct ggccgatgac gacgccgtcc gcgagaccat gttccccatc
    16981 agcgtgaccc gggacgtgat ccacaccgct accccggacg acgccgacac catcggcacc
    17041 ctgatgcgcc agtgggcccg gcagggcggg ctggacgtgc gctggaccga ccgcctggtg
    17101 gaacgctggc tcgtcgacga ccccgccagc ttccagttgg tccgggacgg cggcgaccgg
    17161 atcatcggcc tgacgaacac ccagcaggtc accgaacgca ccatgaactg tgtggaacct
    17221 ctgctccagc agcacacgga ccggctgctc ggccgcccgc gcggcgccgg gggatggctg
    17281 ctcggcgcgg cctactgccc cgaccggggc gcccatgcgc acctgttgcg cggcctgctg
    17341 cgccaggtca tcacgggcgg cctgctgctg acggtgtcca ccccgaaccc ggactaccag
    17401 cggctgctgc gcgggctgcg cttccagcgt cacggcacca ccaccgacga cgtctaccgc
    17461 tgcgggcgca agcccgagat cttcagccag gacttcggct ccgccgcgct gcccgactgg
    17521 acggagcggc tcgcccgcag ctcgggggcg cgcggcggcc cgcgtccgac cggccaggag
    17581 gtggcccgtg ccctcgccgt catcgccgac ccggcccggc tggccgaaag cccgctgctc
    17641 tcctcgccgc gcccccggac ggtggcggaa ctgcgcgcgg acctgtggga ggcggtgcga
    17701 cggctggcgg acagcgaggt gcgcgaggag gccgaggccg ggtggattct ccagcactac
    17761 tacctcggac ggccgcggac ccatcagcgg ctcgcccagc agctccacat cagccgcgcc
    17821 acctacttcc gacggctccg gcacggcctg gacctggtgg gcggcggact cgcggcggaa
    17881 cggagcgtcc catgaggggc gccgggagga cggcagcggc ggggccgggt gcctcagcgg
    17941 cagacctcgc ccggctcagc cctgccggga ccaggagctg cggcaccgtc acgaaggtgt
    18001 agccgcaggc ggtgatgtgc tgtgggcctg cttccagccg ggcagttcct cggcttcgcg
    18061 gtgccggtga ggcatcacga gtccggtgcc cggacagccg ccgtcggcga tggtgatggt
    18121 cgtgccgacg gcagccttgg cccctgactc ctcccatgcc tcgcagtcat ttgcggttgc
    18181 cgggtagtgg ggcggtccac caagacgacg tggcgggtgt cagcgtcgat gacgacctgg
    18241 tggttggtgg agtaccgatt gttcttggac cgctcggcga tggtgtggtc acaggtgggc
    18301 acgagcgtcc cgtccacgat cagtacggtg ccgttggcga aagacttgcg gggccggagc
    18361 gcgatcatcg gcccgagatg gtcgatgatc cggtctgcgg atgacttcga cacgccgaag
    18421 aaaagggcga gttgccgcat cgtcaagttc gtgagccagt aagccgcgac cagcagtgtc
    18481 cggtcctccg gagacaggct ccacggccgc cccttaccga cggcgtccgc accctcgcgc
    18541 cgcagaaccg tcaccagctt cccgaaggaa cgcaggctca gccggcccgg tgaacggagc
    18601 tgtccagaac ggctacgacg tcgtaatcac accagtcaca actggatcat ccccgttgcc
    18661 actgccaccc catgccctcg attctgcgtg agggggttcg tcctctccga gatgggaggg
    18721 cttcggcgtc gagcgcctgg cgcaccgatg agttttctgc cctgcggggg tcctattggc
    18781 agtagcgcac accacagcag tacggcccct acgtgaaccg gagagataac catggcaaca
    18841 gcgcgagagc agtcggccag agtcgaggac cgtgtcgcct ccgccgacgg caccgagatc
    18901 gcgttcgagc agtcgggtcg cgggccggcc gtcgtcctgg tggcctcggc actggcagac
    18961 cgctcggaca cgaccaaact cgcggctctc ctcgcccagc acttcactgt gatcaactac
    19021 gaccggcgcg gacggggtgc cagcggtgac gccaatgctt acgcccccga ccgcgagatt
    19081 gaagacatcg ccgcgttggt cgaacacgtc ggcggttcgg cgtcgctgtt cggctcgtcc
    19141 tccggagcgg ttctcgccct gcgcgcggcc gctgccggag tgaacgtcga ccgcctggct
    19201 ctgtacgatc cgccgttcgt ggtcgccgaa ggcgacgacg ggccgcccaa ggatctcgcg
    19261 cagcagatca ccgtgctgct tgcggaaggt cggcgcagtg acgcggtcaa gtacttcatg
    19321 accagggtgc agggcatgcc cggcatcgcc gtgttcttta tgaagctcat gccgaagatg
    19381 tgggcaaacc tcaccaagct ggccggcact ctgccctatg acatcgcggt catgggtgat
    19441 acccagcaag gcaagccgct cgatgccgag gagtggaaag gggtggccgt acgcacccgt
    19501 gtgttgaccg gcggcaagag cccagccgcg ttccagcgcg ccgccctcgc cgtcaccgag
    19561 atcctgccgc aggccgacca ccgcactctg cccgggctca accatggcgc cgtcgtcatg
    19621 gccccgagga aaatcgcgcc gcagatcatc gagttcatca agggatgagc ttgtcgttcg
    19681 agcggttcgg tggcgcttgg tactcctcct ggtgctcgga gcggagcgcg gcccccctcc
    19741 aactaactga ccgccgaacc ccggacgacc acaacttacg ggacagcccg ggacagccct
    19801 tacttctggg ggtcaagggg tcgcaggttt tcggtggacg tccgggtgca ggtagtgctg
    19861 gcgacgagga gtggatctcc tcgaagcggt ccgcctaggc gtcggctctc ggacggctgt
    19921 ggctgttcct ggccgtcacc gtctgacggg ccccggnnnn nnnnnncgtg acgcgctccg
    19981 ggtcacgtac ggggccgggg tcgaggccgg cggacggccg gtggctccgc gcggtccgcg
    20041 cccgctgctc agccggtgca ggtcgccttg atcgtcgaaa tcgcgtggtg ctcgtacttg
    20101 ctgtcccggc cccggtcgtg gatgcggacg gagagcttct tggcgtcgac ggcgaaggtg
    20161 cccggcacgt tgtaccaggt gccgcggcgg tcctgctggt tgacgtagaa ggagcccacc
    20221 aggttgttgg tcctgggcag gaaccggtcg tacaccgtgt agtagctcgg gtcgccaccg
    20281 acccgcacga tgtccgaact gccgggcacg tggacggaga tgctgcactt cttggcggag
    20341 gcgggaaggt cgaacagcca ggtcgccgag ccgccggagt ccttggagga gctgccggac
    20401 atcggcatgg agaggtactt gcccgcgcag ccgtaaccgc cgaagccgcc gctgtgggtg
    20461 gcccagccct ccttgccgtc actgtagtag ccgtcccgct ggaagcgctg ggtggggcac
    20521 tcgtggccgg acaccccgct gtacaccacg gtgggcgcct tgggcgtcgt ctggggctgc
    20581 gactggggcg cggtctctgc cgagggggc
//
