LOCUS       NZ_CP096281            21311 bp    DNA     linear   CON 08-JUN-2024
DEFINITION  Streptomyces sp. WAC00303 chromosome.
ACCESSION   NZ_CP096281
VERSION     NZ_CP096281.1
KEYWORDS    RefSeq.
SOURCE      Streptomyces sp. WAC00303
  ORGANISM  Streptomyces sp. WAC00303
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1  (bases 1 to 8548838)
  AUTHORS   Meyer,K.J., Tan,S. and Nodwell,J.R.
  TITLE     Genome Sequence of WAC00303 Direct Submission
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 8548838)
  AUTHORS   Meyer,K.J., Tan,S. and Nodwell,J.R.
  TITLE     Direct Submission
  JOURNAL   Submitted (19-APR-2022) Biochemistry, University of Toronto, 1 Kings
            College Circle 5207, Toronto, ON M5S 1A8, Canada
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: 15-MAR-2022
            Assembly Method                   :: Flye v. 2.8.1
            Assembly Name                     :: WAC00303
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 58.0x
            Sequencing Technology :: Oxford Nanopore; Illumina NextSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_023210535.1-RS_2024_06_08
            Annotation Date                   :: 06/08/2024 05:21:48
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 7,823
            CDSs (total)                      :: 7,731
            Genes (coding)                    :: 7,293
            CDSs (with protein)               :: 7,293
            Genes (RNA)                       :: 92
            rRNAs                             :: 6, 6, 6 (5S, 16S, 23S)
            complete rRNAs                    :: 6, 6, 6 (5S, 16S, 23S)
            tRNAs                             :: 71
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 438
            CDSs (without protein)            :: 438
            Pseudo Genes (ambiguous residues) :: 0 of 438
            Pseudo Genes (frameshifted)       :: 228 of 438
            Pseudo Genes (incomplete)         :: 241 of 438
            Pseudo Genes (internal stop)      :: 26 of 438
            Pseudo Genes (multiple problems)  :: 54 of 438
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 18:23:54
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 6930161
            Orig. end                         :: 6951472
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP096281.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            Bacteria and source DNA available from Justin Nodwell, University
            of Toronto.
FEATURES             Location/Qualifiers
     region          1..21311
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene"
                     /region_number="24"
                     /rules="(PT_phytoene_like or phytoene_synt or Lycopene_cycl
                     or Lycopene_cycl_fung or T1TS or T1TS_KS or T2TS or TS_UbiA
                     or TS_Pyr4)"
                     /tool="antismash"
     cand_cluster    1..21311
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /kind="single"
                     /product="terpene"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..21311
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:11311](+)"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..11311
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
     gene            complement(859..1878)
                     /locus_tag="MWG59_RS31845"
                     /old_locus_tag="MWG59_31845"
     CDS             complement(859..1878)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) GFO_IDH_MocA"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) GFO_IDH_MocA_C3"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1079: oxidoreductase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003965313.1"
                     /locus_tag="MWG59_RS31845"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MWG59_31845"
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="WP_248586408.1"
                     /sec_met_domain="GFO_IDH_MocA (E-value: 2.7e-16, bitscore:
                     59.1, seeds: 39, tool: rule-based-clusters)"
                     /sec_met_domain="GFO_IDH_MocA_C3 (E-value: 2.4e-24,
                     bitscore: 84.5, seeds: 4226, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRIGLIGTGRIGTFHAEVLSRHPAVDALLLADAAPERAAGAAART
                     GATAVPVDGLFSGEGAAGGPPDAVVICSATSAHAGLIARAARAGLPVFCEKPIALDLPG
                     TLAALAEVEAAGSVLQLGFMRRFDAGYGEARAAVREGRLGRLHTVRAVTSDPAPPPAAY
                     LPLSGGLYRDCLVHDFDILRWVTGREVSEVYATGSDAGPAMFREAGDVDTAAALLTLDD
                     GTLATATATRCNGAGYDVRMELAGELDQIAVGLDDRTPLTSAEPGGSGAPAKPWPGFLE
                     RFAPAYEAELDAFLRVARGESANPCDGREALHALRIAEACEVSRRERRPVAMTEIPGG"
     misc_feature    1919..1933
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence: weak,
                     score: 15.82"
                     /tool="antismash"
     misc_feature    complement(1920..1933)
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 14.32"
                     /tool="antismash"
     gene            2010..2768
                     /locus_tag="MWG59_RS31850"
                     /old_locus_tag="MWG59_31850"
     CDS             2010..2768
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1136: GntR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018961415.1"
                     /locus_tag="MWG59_RS31850"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MWG59_31850"
                     /product="GntR family transcriptional regulator"
                     /protein_id="WP_097933157.1"
                     /transl_table=11
                     /translation="MTAHGTDRPLPLSVDRTSPVPLYFQLAQQLEAAVEQGRLAPGALL
                     GNEVDLAARLGLSRPTVRQAIQSLVDKGLMVRRRGVGTQVVHSKVRRPLELSSLYDDLE
                     AAGQRPATGVLRNTTEPADAEVAAALGVAEGSEVHLVERLRSAHGEPMALLRNHLPLGL
                     LPLITEELEASGLYRLMRAGGITLHSARQTVGACAADDRQARALSEPVGAPLLTMERTT
                     YDDTGRVVEFGSHVYRAQRYAFEFQLLVRA"
     gene            3152..4132
                     /locus_tag="MWG59_RS31855"
                     /old_locus_tag="MWG59_31855"
     CDS             3152..4132
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1205: ABC
                     transporter, carbohydrate uptake"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014153146.1"
                     /locus_tag="MWG59_RS31855"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MWG59_31855"
                     /product="sugar ABC transporter substrate-binding protein"
                     /protein_id="WP_069755146.1"
                     /transl_table=11
                     /translation="MGAVLAVVLGASLAGCSSTGGKRAEERAAAAAEGRAAVNTPRWTF
                     AMVTHSGDGDTFWDIVQKGAEQAAVKDNINFLYSHNDEANQQAQLVQTAIDKKVDGLIV
                     SLAKPDAMKAVVAKAVKAGIPVVTVNSGSAESKEFGALTHIGQDESIAGEAVGDELNGR
                     DRKKALCVLHEQGNVGHEQRCAGAKKTFDGTMQNLYVDGTNMPDVTASIEAKLQSDKSI
                     DAVVTLGAPFADAAVQAKQTAGSKAEIDTFDLNAKVATGLQTDKLGFAVDQQPYLQGYE
                     AVDLLWLYRYNRNVLGGGLPVLTGPQIITKDDADALADYTKRGTR"
     gene            4129..5175
                     /locus_tag="MWG59_RS31860"
                     /old_locus_tag="MWG59_31860"
     CDS             4129..5175
                     /GO_component="GO:0005886 - plasma membrane [Evidence IEA]"
                     /GO_function="GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /GO_process="GO:0008643 - carbohydrate transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1113:
                     inner-membrane translocator"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018961417.1"
                     /locus_tag="MWG59_RS31860"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MWG59_31860"
                     /product="ABC transporter permease"
                     /protein_id="WP_050357357.1"
                     /transl_table=11
                     /translation="MSGSTAAPDQLDERLVRTSPLRKLLGRPELGSVVGAAAVFLFFAI
                     VADSFLQASSLGTVLYAASVLGIMAAPVALLMIGGEFDLSAGVMVTSSALISSMFSYQM
                     TANVWVGVFVSLLVTLAIGAFNGFMLTRTKLPSFIITLGTFLMLTGLNLGFTKLISGTV
                     STKAIGDMEGFDSARALFASTLTLGGVEFKVTILWWAALVGVATWILLRTRFGNWIFAV
                     GGEADAARAVGVPVIRTKIGLYLGVAFAAWVSGQHLLFSYDVVQSGEGVGNELTYIIAA
                     VIGGCLITGGYGSAIGSAVGAFIFGMTSKGIVYAEWNPDWFKFFLGAMLLLATLLNAWV
                     RKRAEATA"
     gene            5172..6029
                     /locus_tag="MWG59_RS31865"
                     /old_locus_tag="MWG59_31865"
     CDS             5172..6029
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012378422.1"
                     /locus_tag="MWG59_RS31865"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MWG59_31865"
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="WP_097933156.1"
                     /transl_table=11
                     /translation="MTATPEDPAGATAGPLVELDDVSKFYGNIKALEHVSLEVHAGEIT
                     CVLGDNGAGKSTLIKIIAGLHRHDAGRFLIDGEETALANPRDALDRGIATVYQDLAVVP
                     LMPVWRNFFLGSEPTVGVGPFKRLDVRKMRETTRTELLRMGIDLRDVDQPIGTLSGGER
                     QCVAIARAVYFGAKVLVLDEPTAALGVKQSGVVLKYVAAARDAGLGVVLITHNPHHAHL
                     VGDRFILLKRGAMSGSHTKDDVTLDELTRQMAGGSELEELSHELERTPTPTLPGAHGTK
                     DETP"
     gene            6163..7329
                     /locus_tag="MWG59_RS31870"
                     /old_locus_tag="MWG59_31870"
     CDS             6163..7329
                     /EC_number="2.7.1.2"
                     /GO_function="GO:0004340 - glucokinase activity [Evidence
                     IEA]"
                     /GO_process="GO:0006096 - glycolytic process [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1108: ROK family
                     protein"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003965308.1"
                     /locus_tag="MWG59_RS31870"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MWG59_31870"
                     /product="ROK family glucokinase"
                     /protein_id="WP_073869228.1"
                     /transl_table=11
                     /translation="MSTYRDFAHRGSARATVLKTVGTKERRSHLTAPRVPTVGIDIGGT
                     KVMAGVVDADGNILEQLRTETPDKSKSPKVVEDTIVELVLDLSDRHDVHAVGIGAAGWV
                     DADRSKVLFAPHLAWRDEPLRDAIASRLVVPVMVDNDANTAAWAEWRFGAGRGEDHLVM
                     ITLGTGIGGAILEDGQVKRGKYGVAGEFGHMQVVPSGHRCPCGNRGCWEQYSSGNALVR
                     EARELAAADSPVAHYLLDRVKGHIPDITGPLITELAREGDAMCIELLQDIGQWLGVGIA
                     NLAAALDPSCFVIGGGVSAADDLLINPARDAFKRHLTGRGYRPEARIAKAQLGPEAGMV
                     GAADLARLVARRFRRANRRRVERYERYAQIYDQAASTIRNTRSTRTAD"
     gene            7401..7997
                     /locus_tag="MWG59_RS31875"
                     /old_locus_tag="MWG59_31875"
     CDS             7401..7997
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015612389.1"
                     /locus_tag="MWG59_RS31875"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MWG59_31875"
                     /product="hypothetical protein"
                     /protein_id="WP_097933155.1"
                     /transl_table=11
                     /translation="MIAAEHPVVPHQSESPGDGEGKPPEDRRHVFKRRFITATIIVLLI
                     GIPAGYLLISAGQSRRSGQDKEAEAAAQGLREGWPSKMQRRIFEIPIPGNGQGVQYYET
                     NNWKASRMYAKFRTTSAGLDRFLTGVGTGRAALEPDTIDISPRDIKITGWSFAPGEEWA
                     STTHKNKKPRPTQNITVNMTDPASPVVYVVSAATP"
     gene            8499..9911
                     /locus_tag="MWG59_RS31880"
                     /old_locus_tag="MWG59_31880"
     CDS             8499..9911
                     /GO_component="GO:0140737 - encapsulin nanocompartment
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1133:
                     Transcription regulator, crp"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003965306.1"
                     /locus_tag="MWG59_RS31880"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MWG59_31880"
                     /product="family 2B encapsulin nanocompartment shell
                     protein"
                     /protein_id="WP_248586409.1"
                     /transl_table=11
                     /translation="MTVDSSSEARLEVPRQSSLGTAAARNLASTTKSAPQMQEITSRWL
                     LRMLPWVETKGGAYRVNRRLTFTVGDGRVEFVQDGAAVRVIPQELGELALLRDFDDAEV
                     LTAIADRCVQRDFRAGETLVERGTAADQLHLIAHGRIGQTSAGSYGDEVTLDVLADGDR
                     FGEHALLDDDARWTQTATAETAGTLLTLSRADFAAVVANSPDLRAHLAEFTARSGQRQN
                     HRGEAEIAMSAGHVGEHDLPGAFADYELKPREYELSVAQTILRVHTRVADLYNGPMNQT
                     EEQLRLTIEALRERQEHELINNREFGLLHNADFKQRVQTHSGPPTPDDLDELLCRRRGT
                     KFFLAHPRTIAAMGREFNARGLYPDHTDLGGQQVPAWRGVPILPCGKIPITPERTSSIL
                     AMRTGEENQGVIGLRQTGLPDEYEPGLSVRFMGIDEKAIISYLVSTYYSAAILVPDAVG
                     VLENVQIANWPR"
     gene            10001..11311
                     /locus_tag="MWG59_RS31885"
                     /old_locus_tag="MWG59_31885"
     CDS             10001..11311
                     /GO_component="GO:0140737 - encapsulin nanocompartment
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: T1TS"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1052: Terpene synthase/cyclase metal-binding domain
                     protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012378420.1"
                     /locus_tag="MWG59_RS31885"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MWG59_31885"
                     /product="family 2 encapsulin nanocompartment cargo protein
                     terpene cyclase"
                     /protein_id="WP_097933153.1"
                     /sec_met_domain="T1TS (E-value: 1.5e-67, bitscore: 227.7,
                     seeds: 237, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPVPELPPPQSSLPEVVTRFGATVLGAVAARAHDTDAVGGPTGGR
                     PLPGQPAGLSFGPPATALPPTAVPVTDAPGQGVGLERLLRGPHGLGTAGLRLTPREERP
                     VTPAPREGRPIPGLYHHPVPEPDEARVDEVSRRIKAWALDEVSLYPEEWEEQFDGFSVG
                     RYMVGCHPDAPTVDHLMLATRLMVAENAVDDCYCEDHGGSPIGLGERLLLAHTALDPLY
                     TVREYQPEWADSLHADAPRRAYRSAMDYFVRAAGPSQADRLRHDMARLHLGYLAEASWA
                     QQDQVPEVWEYLAMRQFNNFRPCPTITDTVGGYELPADLHARADMQKVIALASNATTIV
                     NDLYSYTKELDAPGRHLNLPVVIAEREGLSDQDAYLKSVEVHNELMHDFETEAAALAAA
                     CPVPAVQRFLRGVAAWVDGNHHWHQSNTYRYSLPDFW"
     misc_feature    10187..10189
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            11345..12223
                     /locus_tag="MWG59_RS31890"
                     /old_locus_tag="MWG59_31890"
     CDS             11345..12223
                     /EC_number="2.1.1.255"
                     /GO_function="GO:0000287 - magnesium ion binding [Evidence
                     IEA]"
                     /GO_function="GO:0008757 - S-adenosylmethionine-dependent
                     methyltransferase activity [Evidence IEA]"
                     /GO_function="GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1089: methyltransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018512513.1"
                     /locus_tag="MWG59_RS31890"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MWG59_31890"
                     /product="geranyl diphosphate 2-C-methyltransferase"
                     /protein_id="WP_050357363.1"
                     /transl_table=11
                     /translation="MTSAELTTAPTLRIPGPATPYQGDIARYWDGEARPVNLRLGDVDG
                     LYHHHYGIGEVDTASLGNPEDSESEKKLITELHRLESAQAEFLLGHLGDIGRDDTLVDA
                     GCGRGGSMVMAHQRFGCSVEGVTLSAKQADFANGRAAELGIGDHVRARVCNMLSTPFAT
                     GSAAASWNNESSMYVDLDDLFAEHSRVLKVGGRYVTITGCWNPRYGQPSKWVSQINAHF
                     ECNIHSRREYLRAMADNRLVPQAVIDLTPDTLPYWELRATSSLVTGIEDAFINSYRDGS
                     FQYLLIAADRV"
     assembly_gap    12238..12247
                     /estimated_length=10
                     /gap_type="within scaffold"
                     /linkage_evidence="paired-ends"
     gene            12415..13401
                     /locus_tag="MWG59_RS31895"
                     /old_locus_tag="MWG59_31895"
     CDS             12415..13401
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF00881"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012378419.1"
                     /locus_tag="MWG59_RS31895"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MWG59_31895"
                     /product="nitroreductase family protein"
                     /protein_id="WP_248586410.1"
                     /sec_met_domain="PF00881 (E-value: 1.8e-10, bitscore: 39.9,
                     seeds: 78, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRDRVTEAVPALVAAAVAAPSMHNAQPWRFVHHTNTGVLSLYGDP
                     ERALPVGDPEHRGMHLGCGGALFNLRVAAAQQGWDAVAEVFPDRRDPWRLVDVTLEEPG
                     TVPFDRGLADLFPAVEARRTNRSPFSDEQIPPEIVDELCAAALLEGARLAVPSDWHADD
                     LVDLVHDAELHEAASDLMRAEIIAWTRTGRAGEGPAAEGVPSYAFGPRQHDVKVPVRDF
                     GLPRDTQRATATFEERPQLAVLGTETDDPADWLRAGQAMERILLVATRDGLATSMMSQP
                     LEWPELRAMARDPASRMGFVHMVFRLGYGPPAAPTPRRPVADVLTVV"
     gene            13531..14817
                     /locus_tag="MWG59_RS31900"
                     /old_locus_tag="MWG59_31900"
     CDS             13531..14817
                     /NRPS_PKS="Domain: Abhydrolase_1 (18-128). E-value:
                     4.7e-22. Score: 70.7. Matches aSDomain:
                     nrpspksdomains_MWG59_RS31900_Abhydrolase_1.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF00561"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Abhydrolase_6"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1036: alpha/beta hydrolase fold protein"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003965293.1"
                     /locus_tag="MWG59_RS31900"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MWG59_31900"
                     /product="alpha/beta fold hydrolase"
                     /protein_id="WP_248586411.1"
                     /sec_met_domain="PF00561 (E-value: 3.8e-16, bitscore: 58.3,
                     seeds: 48, tool: rule-based-clusters)"
                     /sec_met_domain="Abhydrolase_6 (E-value: 3.8e-14, bitscore:
                     52.6, seeds: 455, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSEPRNTLKYCVDGPEEAPVLVIGPSLGTTWHMWDRQIPELSQHW
                     RVFRYDLPGHGGAPAHASASVTDLADRLITTLDGLGIQRFGYAGCSIGGAIGADLALRH
                     PHRVASLALVASSPRFGTADEFRQRGVIVRTNGLEPMARTAPERWFTPGFAAAQPAIVE
                     WAVQMVRTTDPGCYIAACEALAAFDIRGALGRIGAPTLVLVGAEDQVTGPAEARTLVAG
                     IPDARLALVPGASHLAPVEQPAAVSDLLLMHFSTSWQQDTSAAIPVLPIVPGPAKPAAP
                     FAPVAEIAPAAPTPETSAATPDARHEQGTKVRREVLGDAHVDAVNASADGFTEDFQELV
                     TRYAWGEVWSRDGLDRRTRSCITLTALVASGHLEGLAAHTRAALRNGLTPAEIKEVLLQ
                     TAVYCGLPAAGAAFAVAQQVIQEETTPPA"
     aSDomain        13585..13914
                     /aSDomain="Abhydrolase_1"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_MWG59_RS31900_Abhydrolase_1.1"
                     /evalue="4.70E-22"
                     /label="MWG59_RS31900_Abhydrolase_1.1"
                     /locus_tag="MWG59_RS31900"
                     /protein_end="128"
                     /protein_start="18"
                     /score="70.7"
                     /tool="antismash"
                     /translation="PVLVIGPSLGTTWHMWDRQIPELSQHWRVFRYDLPGHGGAPAHAS
                     ASVTDLADRLITTLDGLGIQRFGYAGCSIGGAIGADLALRHPHRVASLALVASSPRFGT
                     ADEFRQ"
     gene            14830..15483
                     /locus_tag="MWG59_RS31905"
                     /old_locus_tag="MWG59_31905"
     CDS             14830..15483
                     /GO_function="GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003965292.1"
                     /locus_tag="MWG59_RS31905"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MWG59_31905"
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="WP_248586412.1"
                     /transl_table=11
                     /translation="MNASPGALTLTKKTHSCVRIEKEGRVLVIDPGGFSEDDAALGADV
                     VLVTHEHPDHFNEARLRVGLEANPAAEIWTLRSVAEQLSAAFPGRVHTVGEGDAFSAAG
                     FDVTVHGELHAVIHPDIPRITNVGFLVDGSVFHPGDALTVPDRPVDTLLLPVMAPWSKI
                     SEVIDYVREVQPRRAIDVHDALLTDLARPIYDNQIGALGGADHGRLAPGGVTEL"
     gene            15526..16305
                     /locus_tag="MWG59_RS31910"
                     /old_locus_tag="MWG59_31910"
     CDS             15526..16305
                     /EC_number="3.1.11.2"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018961423.1"
                     /locus_tag="MWG59_RS31910"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MWG59_31910"
                     /product="exodeoxyribonuclease III"
                     /protein_id="WP_097933150.1"
                     /transl_table=11
                     /translation="MRIATYNVNSITARLPRLLAWLESSGTDVLCIQETKCTAEQFPTA
                     ALAELGYESAVNATGRWNGVALLSRVGLSDVVTGLPDGPDYDGVQEPRAISATCGPLRL
                     WSVYVPNGREVEHEHYAYKLRWLEALRKAVAADAAKALPFAVLGDFNVAPTDEDVWDPA
                     LFAGATHVTPAERAALTALEAEGLSEVLPRPLKYDRAYTFWDYRELRFPKNKGMRIDLT
                     FGNAPFAAAVKDSYVDREERKGKGASDHAPVVVDLDL"
     gene            16388..17134
                     /locus_tag="MWG59_RS31915"
                     /old_locus_tag="MWG59_31915"
     CDS             16388..17134
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015612393.1"
                     /locus_tag="MWG59_RS31915"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MWG59_31915"
                     /product="Clp protease N-terminal domain-containing
                     protein"
                     /protein_id="WP_097933149.1"
                     /transl_table=11
                     /translation="MTQPLPAAPSVRLDDLIEAIKKSNTDALEQLSGAVIAADHLGDVA
                     DHLIGHFVDQARRSGASWTDIGRSMGVTRQAAQKRFVPKKGDGASDLDPSQGFGRFTQR
                     ARNVVMAAHNEAQAARHAEILPAHLVLGLLAEPESIAAGVLLGPEVTADALRTAATAAL
                     PAAAEEVPELIPYDADSRKVLELTFREALRLGHNYVGTEHILLALLEFEGGSGVLSGLG
                     VEKDAASAAVEAAVTEAAAALWQQKS"
     assembly_gap    17222..17231
                     /estimated_length=10
                     /gap_type="within scaffold"
                     /linkage_evidence="paired-ends"
     gene            17393..18139
                     /locus_tag="MWG59_RS31920"
                     /old_locus_tag="MWG59_31920"
     CDS             17393..18139
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015612393.1"
                     /locus_tag="MWG59_RS31920"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MWG59_31920"
                     /product="Clp protease N-terminal domain-containing
                     protein"
                     /protein_id="WP_097933149.1"
                     /transl_table=11
                     /translation="MTQPLPAAPSVRLDDLIEAIKKSNTDALEQLSGAVIAADHLGDVA
                     DHLIGHFVDQARRSGASWTDIGRSMGVTRQAAQKRFVPKKGDGASDLDPSQGFGRFTQR
                     ARNVVMAAHNEAQAARHAEILPAHLVLGLLAEPESIAAGVLLGPEVTADALRTAATAAL
                     PAAAEEVPELIPYDADSRKVLELTFREALRLGHNYVGTEHILLALLEFEGGSGVLSGLG
                     VEKDAASAAVEAAVTEAAAALWQQKS"
     gene            complement(18173..18952)
                     /locus_tag="MWG59_RS31925"
                     /old_locus_tag="MWG59_31925"
     CDS             complement(18173..18952)
                     /NRPS_PKS="Domain: PKS_KR (16-186). E-value: 4e-12. Score:
                     38.3. Matches aSDomain:
                     nrpspksdomains_MWG59_RS31925_PKS_KR.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) adh_short"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1001: short-chain dehydrogenase/reductase SDR"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006128628.1"
                     /locus_tag="MWG59_RS31925"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MWG59_31925"
                     /product="SDR family oxidoreductase"
                     /protein_id="WP_097933148.1"
                     /sec_met_domain="adh_short (E-value: 1.3e-29, bitscore:
                     102.3, seeds: 230, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSAHAYVSELFSLEGRVAVVTGGSSGIGRAITGALARAGAGVVVV
                     ARREAELRATVDELTAEGCRAAWVSADLSTAEGVRAGADGAAQAFGEPDILVNCAGINL
                     RPPMAELGEDVWDTTMAVNLKAPFLLGQRFGPGMAERGYGRIIHVTSQQAHRAFVDSGA
                     YGVSKGGLESLARSQAEAWSPHGVTVNTLVPGFVLTPLNRSLASDPEKVASLAARTLVG
                     RNGLVEDFAGAAVFLAGRSSAYVTGQSVFVDGGFSVH"
     aSDomain        complement(18395..18904)
                     /aSDomain="PKS_KR"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_MWG59_RS31925_PKS_KR.1"
                     /evalue="4.00E-12"
                     /label="MWG59_RS31925_PKS_KR.1"
                     /locus_tag="MWG59_RS31925"
                     /protein_end="186"
                     /protein_start="16"
                     /score="38.3"
                     /specificity="KR activity: inactive"
                     /specificity="KR stereochemistry: C2"
                     /tool="antismash"
                     /translation="VAVVTGGSSGIGRAITGALARAGAGVVVVARREAELRATVDELTA
                     EGCRAAWVSADLSTAEGVRAGADGAAQAFGEPDILVNCAGINLRPPMAELGEDVWDTTM
                     AVNLKAPFLLGQRFGPGMAERGYGRIIHVTSQQAHRAFVDSGAYGVSKGGLESLARSQA
                     EAWSPHG"
     CDS_motif       complement(18809..18898)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_MWG59_RS31925_0001"
                     /evalue="4.80E-05"
                     /label="PKSI-KR_m1"
                     /locus_tag="MWG59_RS31925"
                     /protein_end="48"
                     /protein_start="18"
                     /score="16.0"
                     /tool="antismash"
                     /translation="VVTGGSSGIGRAITGALARAGAGVVVVARR"
     gene            19062..19502
                     /locus_tag="MWG59_RS31930"
                     /old_locus_tag="MWG59_31930"
     CDS             19062..19502
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006128629.1"
                     /locus_tag="MWG59_RS31930"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MWG59_31930"
                     /product="DUF6278 family protein"
                     /protein_id="WP_047179583.1"
                     /transl_table=11
                     /translation="MNIPFLDNWRKRQGGTRSGALAAAVEADPDGVAELLAECELLRVR
                     AGQHGLELDDTPASLAALDQLPPRWRDDPEELPWLGNDAGLYLGTVIVRTVPGAAWDVW
                     PSGQPVVRLESGREIDVVAAGLDWAMAGSPELSQVYAESAEN"
     misc_feature    19063..19077
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: weak, score: 18.26"
                     /tool="antismash"
     misc_feature    complement(19073..19086)
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 13.42"
                     /tool="antismash"
     gene            19650..20393
                     /locus_tag="MWG59_RS31935"
                     /old_locus_tag="MWG59_31935"
     CDS             19650..20393
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006377699.1"
                     /locus_tag="MWG59_RS31935"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MWG59_31935"
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="WP_007454870.1"
                     /transl_table=11
                     /translation="MAVDPLIELRDVNKHFGELHVLQDINLTVGRGEVVVVIGPSGSGK
                     STLCRAINRLETIESGSIMIDGRPLPEEGKGLAQLRAEVGMVFQSFNLFAHKTVLDNVS
                     LAQLKVRKRKKDEADRRSGELLERVGLAAHADKFPAQLSGGQQQRVAIARALAMDPKAL
                     LFDEPTSALDPEMINEVLEVMQQLARDGMTMVVVTHEMGFARSAANRVVFMSDGCVVED
                     RTPEDFFTNPSSDRAKDFLSKILKH"
     misc_feature    complement(19684..19693)
                     /note="TFBS match to ToxT, Regulator of MSHA biosynthesis,
                     confidence: weak, score: 15.11"
                     /tool="antismash"
     misc_feature    20704..20718
                     /note="TFBS match to VqsM, Regulator of quorum-sensing
                     signalling systems, confidence: medium, score: 18.42"
                     /tool="antismash"
     misc_feature    complement(21033..21046)
                     /note="TFBS match to ANR, Anaerobic transcriptional
                     regulator, confidence: medium, score: 20.8"
                     /tool="antismash"
ORIGIN
        1 ggactcgatg ctcgcggccc cggcccgtgg ggcggacctg gtcgaggcgc tctccttccc
       61 gctgcccatg tcggtgatct gcgagctgct cggcgtcccg tccctggacc gcgaggcctt
      121 ccgcacctgg tccggccagg cggtctcctc cgtcgacccg tccctgcgcg cctcctccac
      181 gcaggcgatg accgcgtaca tcgccgggct gctcgccgac aagcgcgaga aaccgggcga
      241 ggacctgctg agcgcgctga tccacacctc cgacgaggac ggcgaccggc tgtccggcga
      301 cgaactgatc ggcatggcct ggctgttgct ggtcgccgga cacgagacca ccgtcaacct
      361 catcaccaac ggcgtgcaca acctcctcgc ccaccccgat caactggccg ccctgcgagc
      421 cgacttcaca ctgatcgaca acgcggtcga ggagatcctg cgcttcgagg ggccggtgga
      481 gacccccacc taccgcttca cgaccgatcc ggtcgagatc gccggggtga tgatccccgg
      541 cggcggtgaa ctggtcctcg tcgcgatgtc ggacgccaac cgggaccccg tccgctaccc
      601 cgacggatcc cgcttcgaca tcacccgcga cgcccggggt cacatcgcct tcgggcacgg
      661 catccactac tgcctgggcg cgccgctggc ccgcatcgag gccaggatcg ccatccggtc
      721 gctgctggaa cgctgtccgg acctgcggct ggccgccgac ccggcgacgc tcgcctggcg
      781 caccgggatc ctgatgcggg ggccgctgag cctcccggtc gcctggtagc ggccggcccg
      841 gcaggtccgg ggcccggctc agccgccggg gatctcggtc atcgccaccg gtcggcgttc
      901 ccggcgggag acctcgcacg cctcggcgat ccgcagggcg tgcagggcct cccgcccgtc
      961 gcacggattg gccgactcgc cccgggccac gcgcaggaac gcgtccagtt ccgcctcgta
     1021 cgccggggcg aaccgttcca ggaaccccgg ccagggcttc gccggggcgc cggaaccccc
     1081 gggctcggca gaggtcagcg gcgtacggtc gtccaggccg acggcgatct ggtccagttc
     1141 gccggccagc tccatccgta cgtcgtaccc ggcgccgttg caccgggtcg cggtggcggt
     1201 ggcgagcgtc ccgtcgtcga gggtgagcag agcggcggcc gtgtccacgt ccccggcctc
     1261 ccggaacatc gcgggtccgg cgtccgagcc ggtggcgtac acctcgctca cctcgcggcc
     1321 cgtcacccag cgcaggatgt cgaagtcgtg gaccagacag tcgcggtaca gcccgccgga
     1381 gagcgggagg taggcggcgg gcggcggggc cggatcggag gtgaccgccc gcacggtgtg
     1441 cagccggccg agccgtccct cccgcacggc ggccctggcc tcgccgtacc cggcgtcgaa
     1501 gcgccgcatg aagccgagct ggagaacgct gcccgccgcc tcgacctccg cgagcgcggc
     1561 gagcgtgccg ggcaggtcca gggcgatcgg cttctcgcag aagacgggca gcccggcgcg
     1621 ggcggcccgc gcgatgagcc cggcatgggc cgacgtcgcc gaacagatca ccacggcgtc
     1681 gggcgggccc ccggccgcgc cctctccgct gaacagaccg tccaccggga cggccgtcgc
     1741 ccccgtccgc gctgcggctc cggccgcccg ctccggagcc gcgtccgcca gcagcagggc
     1801 gtccacggcg gggtggcggc tgagcacctc cgcatggaat gtgccgatcc gtcccgttcc
     1861 gatcagtccg atgcgcatgg gccccaaggt ggcgttcgcc cggtcgtcat gtcaagcgtt
     1921 tgtcctgaca aatggcggcc gcaccgatcg gctgctcccc gccccggtac gccatggctt
     1981 tgtccggaca agcgaactac gctcgccccg tgaccgcaca tggaaccgac cggccgctgc
     2041 cgctgagtgt ggaccgcacc agcccggtgc cgctctactt ccagctggcg cagcagctgg
     2101 aggccgccgt ggaacagggc cggctggccc ccggcgccct gctcgggaac gaggtcgacc
     2161 tcgccgcccg cctcggcctg tcccggccga ccgtccgcca ggccatccag tcgctcgtcg
     2221 acaagggcct gatggtccgc cgccggggag tcggcaccca ggtcgtccac agcaaggtcc
     2281 gccgcccgct ggagctcagc tcgctctacg acgacctgga ggcggccggc cagcgccccg
     2341 ccaccggcgt cctgcgcaac accacggaac cggccgacgc cgaggtcgcc gccgccctcg
     2401 gcgtcgccga gggcagtgag gtccacctcg tcgaacggct gcgcagcgcc cacggcgaac
     2461 cgatggccct cctgcgcaac cacctgcccc tcgggctgct gcccctgatc accgaggaac
     2521 tggaggccag cggcctctac cggctgatgc gggccggtgg catcacgctg cacagcgccc
     2581 gccagaccgt cggcgcgtgc gccgcggacg accggcaggc acgggcgctg tcggagcccg
     2641 tgggcgcccc gctgctcacg atggagcgca ccacgtacga cgacaccggc cgggtggtcg
     2701 agttcggctc gcacgtctac cgggcgcagc ggtacgcctt cgagttccag ctcctggtac
     2761 gcgcctgagc ccgtccggcc caccctggcg cttccagccc gtccggcgtt tgaggacgga
     2821 accgtcgacg tggtgtccgc cgcgctcgtc gggcgcctgc gccccggggc ccgccggtcc
     2881 tcgaaccccg gacgggctca agaggtccgc cgcgccaacc gccgcgtaag catgttcgga
     2941 caaacggttg acgtgaacat gtggcgcgac tagaactcgc tgcaccgaag gacgcgcccc
     3001 caccggccct gccgggcggg agcgggcggg gctcggggat acttgggcag ccgggccggg
     3061 accgtacact ccccggcccc gtcaagcagc acagcgagca gcagtagaag ggcacggcgt
     3121 cgtggcaagg gttcggacag gggtacgcgc gatgggcgcc gtgctggcag tggtgctggg
     3181 cgcctccctc gcgggatgca gcagcaccgg cggcaagcgc gccgaggagc gcgcggccgc
     3241 cgcggccgag ggacgggccg cggtgaacac accgcgctgg accttcgcca tggtcaccca
     3301 ctcgggcgac ggcgacacct tctgggacat cgtccagaag ggcgccgagc aggcggccgt
     3361 gaaggacaac atcaacttcc tctactcgca caacgacgag gccaaccagc aggcccagct
     3421 cgtccagacc gcgatcgaca agaaggtcga cgggctgatc gtctcgctgg ccaagccgga
     3481 cgcgatgaag gccgtggtcg ccaaggccgt caaggcgggc atcccggtcg tcaccgtgaa
     3541 ctcgggctcc gcggagtcca aggagttcgg cgcgctcacc cacatcggcc aggacgagtc
     3601 gatcgccggc gaggccgtcg gcgacgagct gaacggccgg gaccgcaaga aggccctctg
     3661 cgtcctgcac gagcagggca acgtgggcca cgagcagcgc tgcgccgggg cgaagaagac
     3721 cttcgacggc acgatgcaga acctgtacgt cgacggcacc aacatgcccg acgtcaccgc
     3781 gtccatcgag gccaagctcc agtccgacaa gagcatcgac gcggtcgtca ccctcggggc
     3841 ccccttcgcc gacgcggccg tccaggccaa gcagaccgcc ggcagcaagg ccgagatcga
     3901 caccttcgac ctgaacgcca aggtcgccac cggcctccag accgacaagc tcggcttcgc
     3961 cgtcgaccag cagccctacc tccagggcta cgaggccgtc gacctgctct ggctctaccg
     4021 ctacaaccgc aacgtcctcg gcggcggcct ccccgtcctg accggcccgc agatcatcac
     4081 caaggacgac gccgacgccc tggccgacta caccaagcgg ggcacgcgat gagcggctcc
     4141 accgccgccc ccgaccagct ggacgagcgg ctggtgcgca cctcgccgct gcgcaagctg
     4201 ctgggccgcc ccgagctcgg ctcggtcgtc ggcgcggcgg ccgtcttcct gttcttcgcg
     4261 atcgtcgccg acagcttcct ccaggcctcc agcctcggca ccgtgctgta cgcggcctcc
     4321 gtcctcggca tcatggccgc accggtcgcc ctgctgatga tcggcggcga gttcgacctg
     4381 tccgccgggg tcatggtgac cagctccgcg ctgatctcct cgatgttcag ctaccagatg
     4441 acggccaacg tctgggtcgg cgtcttcgtg tcgctgctgg tcacgctcgc catcggcgcg
     4501 ttcaacggct tcatgctgac ccgcaccaaa ctgccgagct tcatcatcac gctcggcacg
     4561 ttcctgatgc tgaccggcct gaacctcggc ttcaccaagc tcatcagcgg caccgtctcc
     4621 accaaggcca tcggcgacat ggagggcttc gactcggccc gcgcgctgtt cgcctcgacg
     4681 ctgaccctcg gcggcgtcga gttcaaggtg acgatcctgt ggtgggcggc gctcgtcggc
     4741 gtggccacct ggatcctcct ccgtacccgc ttcggcaact ggatcttcgc cgtcgggggc
     4801 gaggccgacg cggcccgcgc ggtcggcgtc ccggtcatcc gcaccaagat cgggctctac
     4861 ctgggcgtcg ctttcgccgc ctgggtctcc ggccagcacc tgctgttcag ctacgacgtc
     4921 gtccagtccg gcgagggcgt cggcaacgag ctgacgtaca tcatcgccgc cgtcatcggt
     4981 ggctgcctga tcaccggcgg ctacggctcc gcgatcggct cggccgtcgg cgccttcatc
     5041 ttcggcatga ccagcaaggg catcgtgtac gccgagtgga acccggactg gttcaaattc
     5101 ttcctgggag cgatgctgct cctggccacc ctgctcaacg cgtgggtgcg caagcgcgcg
     5161 gaggcgacgg catgacggcc acccctgaag accctgccgg agcgaccgcc ggaccgctgg
     5221 tcgagctcga cgacgtgtcc aagttctacg ggaacatcaa ggccctggaa catgtctcgc
     5281 tggaggtcca cgcgggcgag atcacgtgcg tcctcgggga caacggcgcc ggcaagtcca
     5341 ccctcatcaa gatcatcgcg gggctgcacc ggcacgacgc cggacgcttc ctgatcgacg
     5401 gcgaggagac cgcgctcgcc aacccgcgcg acgccctgga ccggggcatc gccacggtct
     5461 accaggacct cgccgtcgtc ccgctgatgc cggtctggcg gaacttcttc ctcggctccg
     5521 agcccaccgt cggcgtcggc cccttcaagc gcctcgacgt ccggaagatg cgcgagacga
     5581 cccgtaccga actgctgcgc atgggcatcg acctgcgcga tgtcgaccag cccatcggca
     5641 ccctgtccgg cggcgagcgc cagtgcgtgg ccatcgcccg cgccgtctac ttcggtgcga
     5701 aggtcctggt cctggacgag ccgaccgccg cactcggcgt caagcagtcc ggtgtggtcc
     5761 tcaagtacgt ggcggccgcc cgcgacgccg gcctcggcgt ggtcctcatc acgcacaacc
     5821 cgcaccacgc ccacctcgtc ggcgaccgct tcatcctcct caagcgcggc gcgatgtccg
     5881 gcagccacac caaggacgac gtcacgctgg acgagctgac tcggcagatg gcgggcggca
     5941 gcgagctgga ggagctcagc cacgagctgg aacgcacccc gacccccacc ctcccgggcg
     6001 cccacggcac gaaggacgag actccctgag cggcgaccgc cccggcgcgg ccgaccccgc
     6061 ccaccggccc cccggggccg ggcagtggca gaatcgagcc cggcgggcgc cgtccgccac
     6121 cggccgcgac agcggcccgg ccccccagac cccgcaggga cgatgagcac gtaccgcgac
     6181 ttcgcacacc gcggctccgc ccgcgccacc gtcctcaaga ccgtcggcac caaggaacgc
     6241 cgctcgcacc tcaccgcccc ccgggtcccc acggtcggga tcgacatcgg cggcaccaag
     6301 gtgatggcgg gcgtcgtgga cgccgacggc aacatcctgg aacagctccg caccgagacg
     6361 cccgacaagt ccaagagccc caaggtcgtc gaggacacca tcgtcgaact ggtcctggac
     6421 ctctccgacc gccacgacgt ccacgcggtg ggcatcggcg cggcgggctg ggtggacgcc
     6481 gaccgctcca aggtcctgtt cgccccgcac ctcgcctggc gcgacgaacc cctgcgcgac
     6541 gccatcgcct cccgcctcgt cgtccccgtc atggtcgaca acgacgccaa cacggcggcc
     6601 tgggcggaat ggcgcttcgg tgcgggccgc ggcgaggacc acctcgtcat gatcaccctc
     6661 ggtacgggca tcggcggcgc gatcctggag gacggccagg tcaagcgcgg caagtacggc
     6721 gtggccggtg agttcggcca catgcaggtc gtgccttccg gccaccgctg cccctgcggc
     6781 aaccggggct gctgggagca gtacagctcc ggcaacgccc tggtccgcga ggccagggaa
     6841 ctggccgccg ccgactcccc ggtcgcgcac tacctgctgg accgggtgaa gggccacatc
     6901 cccgacatca ccggtccgct catcaccgaa ctggcccgcg agggcgatgc gatgtgcatc
     6961 gaactcctcc aggacatcgg ccagtggctc ggcgtgggca tcgccaatct ggccgccgcg
     7021 ctcgacccct cctgcttcgt catcggaggc ggtgtcagtg cagccgacga ccttctgatc
     7081 aaccccgcca gggacgcctt caagcgtcac ctcaccggcc gcggctaccg ccccgaggcc
     7141 cggatcgcga aggcgcagct cggccccgag gcgggtatgg tcggcgccgc ggacctggcc
     7201 aggctggtcg cccgccgatt ccgccgggcc aaccggcggc gcgtcgagcg gtacgagcgg
     7261 tacgcccaga tctacgacca ggcggcgagc accatccgca acacgcggtc cacccgtacc
     7321 gctgactgaa ccacagccgc cctttccggc gtccaccctt cagtacgccg tcaccgcagc
     7381 accttaggga ccacctgatc atgatcgcag ccgagcaccc cgtggtgccg caccagtcgg
     7441 aatccccggg cgacggcgag ggcaagccgc ccgaggaccg gcggcatgtg ttcaagcggc
     7501 gtttcatcac cgcgacgatc atcgtgctgc tgatcggcat cccggccggc tacctgctga
     7561 tctcggccgg tcagagccgc cgctcgggcc aggacaagga ggccgaggcg gccgcccagg
     7621 ggctccgcga gggctggccc tccaagatgc agcgccggat cttcgagatc ccgatccccg
     7681 gcaacgggca gggcgtccag tactacgaga ccaacaactg gaaggccagc cggatgtacg
     7741 cgaagttccg gacgacctcc gccggtctcg accgcttcct gaccggggtg ggcaccggac
     7801 gcgcggcgct ggagcccgac acgatcgaca tcagcccccg ggacatcaag atcaccggct
     7861 ggtccttcgc cccgggcgag gaatgggcca gcaccacgca caagaacaag aagccgcgcc
     7921 cgacccagaa catcacggtc aacatgaccg acccggccag cccggtcgtt tacgtcgtct
     7981 cggcggcgac cccctgaccg ggaccctctg agcacatcga cccggcaccg ggtgcgccgc
     8041 gccgccaccg agcgcgtcga cccggtggcg ccgcgtgcgt gtcggccccg gcggtgatcc
     8101 accgccgggg ccgcagtgtg tccgcgtgct gtcgtgttcg cgggcgctct accgtgtccc
     8161 gcgcgtcatc ctcgccgtcg gcctgccccg accggccgga ttgcatcgcg cctccgcggc
     8221 ttcgatcccg tgcgggcccg gaaggatgcc gaacaccctg ctccgatgac ggccgaaatc
     8281 cgtccgcgca ggggcaaaca tcctgcgggc gcgatcatcg tatcgagcta atgtcagcgg
     8341 atttccttgg tccggaggcc ggaggggacc ctagtgttcc cctggatctg atctggaggg
     8401 attctccttc atatcgccct tttgcctcac tttttcatcc tttcgtaggt tcgcgtccgc
     8461 tatgcgcgtt cccgctccga ccaaggagag cctgcccgat gactgttgac tcgagctcgg
     8521 aagcgcggct ggaagtgccc cgccagtcca gcctggggac ggccgccgcc cgcaacctcg
     8581 ccagcacgac gaagtccgcc ccgcagatgc aggagatcac ctcccgttgg ctgctgcgga
     8641 tgcttccctg ggtcgagacc aagggcggcg cctaccgggt caaccggcgg ctcaccttca
     8701 ccgtgggcga cgggcgggtg gagttcgtcc aggacggggc cgcggtccgg gtcatccccc
     8761 aggagctggg cgaactggcc ctgctgcggg acttcgacga cgccgaggtg ctgacggcca
     8821 tcgccgaccg gtgcgtccag cgtgatttcc gggccgggga gacgctggtg gagcggggca
     8881 cggccgcgga ccagctccat ctgatcgcgc acggccggat cggccagacc tccgccggca
     8941 gctacggcga cgaggtcacc ctggacgtcc ttgcggacgg cgaccgcttc ggcgagcacg
     9001 ccctgctgga cgacgacgcc cggtggacgc agaccgccac cgccgagacc gcgggcacgc
     9061 tgctcaccct gtcccgcgcc gacttcgcgg ccgtcgtggc gaactcgccg gacctccggg
     9121 cccacctcgc cgagttcacc gcgcgctccg ggcagcggca gaaccaccgt ggtgaggcgg
     9181 agatcgcgat gtcggccggc cacgtcggcg agcacgatct gcccggagcg ttcgccgact
     9241 acgaactgaa gccgcgcgag tacgaactct cggtcgccca gaccatcctg cgggtccaca
     9301 ccagggtcgc cgacctctac aacggcccga tgaaccagac cgaggaacag ctcaggctca
     9361 ccatcgaggc gctgcgggag cgccaggagc acgagctgat caacaaccgg gagttcggcc
     9421 tgctccacaa cgccgacttc aagcagcgcg tccagacgca ttccggcccg ccgaccccgg
     9481 acgacctgga cgagctgctc tgccgccgcc ggggcaccaa gttcttcctc gcgcaccccc
     9541 ggacgatcgc ggcgatgggg cgcgagttca acgcgcgcgg cctctacccg gaccacaccg
     9601 acctcggtgg ccagcaggtt cccgcctggc gcggtgtgcc gatcctgccc tgcggcaaga
     9661 tccccatcac cccggagagg accagctcga tcctcgccat gcgtaccggc gaggagaacc
     9721 agggcgtcat cggtctccgg cagaccggcc tgccggacga gtacgaaccg ggcctctcgg
     9781 tccgcttcat gggcatcgac gagaaggcga tcatctccta cctcgtcagc acgtactact
     9841 ccgccgcgat cctcgtgccc gacgcggtcg gcgtcctgga gaacgtgcag atcgccaact
     9901 ggcccaggta gtggtcgcgg cccacgcggc ccggccccgc gaagcgggcc gcctgcccgg
     9961 acgccgtaga acacccgccc cccaccaagg agagccacgc atgcccgtgc ccgagctgcc
    10021 acctccgcag tcgagcctgc cggaggtcgt cacccgcttc ggggcgaccg tgctcggcgc
    10081 ggtcgcggct cgcgcccatg acaccgatgc cgtcggcgga ccgaccggcg gacgccccct
    10141 gccgggccag cccgccgggc tgtccttcgg cccgccggcc accgccttac cgccgaccgc
    10201 cgtaccggtg accgatgcgc ccgggcaggg cgtcgggctg gagcggctgc tgcgcgggcc
    10261 ccacgggctg ggcacggccg ggctgcggct gacgccccgc gaggaacgtc ccgtaacgcc
    10321 ggccccccgg gaaggccggc cgatcccggg cctgtaccac catccggtcc ccgagcccga
    10381 cgaggcgcgc gtcgacgagg tcagccggag gatcaaggcc tgggcgctgg acgaggtctc
    10441 tctgtacccc gaggagtggg aggagcagtt cgacggcttc tccgtgggcc gctacatggt
    10501 cggatgccat ccggacgcgc ccaccgtcga ccacctgatg ctcgccaccc gtctgatggt
    10561 cgccgagaac gcggtggacg actgctactg cgaggaccac ggcgggtcac ccatcggcct
    10621 gggcgagcgg cttctgctcg cgcacaccgc gctcgacccc ctgtacaccg tgcgcgagta
    10681 ccagccggag tgggcggact cgctccacgc ggacgccccc cggcgcgcct accgctccgc
    10741 catggactac ttcgtccgcg cggccgggcc ctcccaggcg gaccggctcc gccacgacat
    10801 ggcgcgactg cacctcgggt atctcgccga agcgtcctgg gcacaacagg accaggtccc
    10861 tgaggtctgg gagtacctgg cgatgcgcca gttcaacaac ttccggccct gccccaccat
    10921 caccgacacc gtcggcggtt acgagctccc ggcggacctg cacgcccggg ccgacatgca
    10981 gaaggtcatc gctctggcct ccaacgccac gacgatcgtg aacgacctct actcgtacac
    11041 caaggagctc gacgccccgg gccggcacct gaacctgccc gtcgtgatcg ccgaacgcga
    11101 ggggctgtcc gaccaggacg cctacctcaa gtcggtcgag gtccacaacg agctgatgca
    11161 cgacttcgag accgaggccg cggcgctggc cgccgcctgc cccgtcccgg ccgtgcagcg
    11221 cttcctgcgg ggcgtcgccg cctgggtcga cggcaatcac cactggcacc aatcgaacac
    11281 ctaccgctac agcctgcccg acttctggta ggccccgaca tccggcaaga gatgggaacc
    11341 atctgtgacc agcgctgaac tcaccaccgc ccccaccctg cgtatccccg gccccgcgac
    11401 gccctaccag ggagacatcg cccgctactg ggacggggag gcccggcccg tgaacctacg
    11461 cctcggcgat gtcgacggtc tctaccacca ccactacggc atcggtgagg tcgacaccgc
    11521 ttcgctcggc aaccccgagg acagcgagag cgagaagaag ctgatcaccg agctccaccg
    11581 gctggagtcg gcccaggccg agttccttct ggggcacctc ggtgacatcg ggcgcgacga
    11641 cacgctggtg gacgcgggct gcggccgggg tggctcgatg gtgatggcgc accagcgctt
    11701 cggctgttcc gtggaaggcg tgacgctgtc ggccaagcag gccgacttcg ccaatgggcg
    11761 cgccgcggaa ctgggaatcg gcgaccacgt ccgcgcccgc gtctgcaaca tgctctccac
    11821 gcccttcgcg accggttccg ccgcggcgtc gtggaacaac gagtcgagca tgtacgtgga
    11881 cctggacgac ctcttcgccg agcactcccg cgtcctgaag gtcggcggtc gctacgtgac
    11941 catcaccggc tgctggaacc cgcgctacgg ccagccctcg aagtgggtct cgcagatcaa
    12001 cgcgcacttc gagtgcaaca tccactcgcg ccgggagtac ctgcgcgcca tggccgacaa
    12061 ccgcctggtg ccgcaggccg tcatcgacct cacccccgac accctgccct actgggagct
    12121 gcgcgccacg tcctcgctgg tcacggggat cgaggacgcg ttcatcaact cctaccggga
    12181 cgggtccttc cagtacctcc tcatcgcggc cgaccgcgtc tgacggcgcc cggtccannn
    12241 nnnnnnngca ccggggacac cctcggtgcc ggccggccat ctcggcgttc ggcatgagcc
    12301 ggtacggccg cggggttagt ttggagggag gcggtccgat cgggtggaag cggccggacg
    12361 catcgcggtt caccggggcg gcgcgacggc cttgtggagc gagaaggaac tgtgatgaga
    12421 gaccgagtca ccgaagcggt cccggcactg gtggcggcgg cggtcgccgc gccgtccatg
    12481 cacaacgccc agccgtggag attcgtccac cacacgaaca ccggcgtcct ctcgctctac
    12541 ggcgatccgg agcgtgctct gccggtcggc gaccccgagc accggggcat gcatctcgga
    12601 tgcgggggcg cgctgttcaa tctgcgggtg gccgccgctc agcagggctg ggacgcggtc
    12661 gccgaggtgt tcccggaccg ccgggatccc tggcgtctgg tcgatgtcac gctggaggag
    12721 cccggcaccg tgcccttcga ccgggggctg gcggacctct tccccgctgt ggaggcccgg
    12781 cgcaccaacc gctccccgtt ctccgacgag cagatcccgc cggagatagt cgacgagctg
    12841 tgcgcggccg cgctcctgga aggggcccgg ctcgccgttc ccagcgactg gcacgccgat
    12901 gacctcgtcg acctcgtgca cgacgcggag ctccacgagg ccgccagcga tctcatgcgg
    12961 gcggagatca tcgcctggac gcgcacgggg agggcggggg aggggccggc ggccgaggga
    13021 gtgccctcct acgcgttcgg tccgcgccag cacgacgtga aggtgcccgt gcgggacttc
    13081 gggctgcctc gggacacgca gcgtgccacg gccacattcg aggagcgccc tcagctggcg
    13141 gtgctcggca cggagacgga tgaccccgcc gactggctcc gggcagggca ggccatggag
    13201 cggatcctgc tcgtggcgac gcgggacggc ctggcgacct cgatgatgtc gcagccgctg
    13261 gaatggccgg agctgagggc gatggcccgt gatcccgcat ccaggatggg cttcgtccat
    13321 atggtcttcc gcctcggcta cggacccccg gcggcgccca ccccgcgcag accggtcgcc
    13381 gatgtgctca ccgtcgtgtg acgcaccggt gcgtgcccgg ccgcaccacc gcactcccgc
    13441 cccgttccct ccccgccggg acggccggct ccccgtcgct tcgacggcct gagttggggc
    13501 agacggtcgc gggatgagag ggtcgagcgg gtgagcgagc cacggaacac cctcaagtac
    13561 tgcgtcgacg gcccggaaga ggctccggtc ctggtcatag gcccctcgct gggtactaca
    13621 tggcacatgt gggaccgcca gatacccgag ctgtcccagc actggcgggt cttccgctac
    13681 gacctgcccg gccacggcgg cgcgcccgcc cacgcctcgg cctccgtcac cgatctggcc
    13741 gaccggctga tcacgacgct ggacgggctc ggcatccaga ggttcggcta cgcgggctgc
    13801 tcgatcggcg gggcgatcgg cgcggacctg gcactgagac atccgcaccg ggtggcctcg
    13861 ctggcgctcg tcgcctcctc gccccggttc ggcacggccg acgagttccg ccagcgcggc
    13921 gtgatcgtcc gtaccaacgg tctggagccg atggcccgca ccgcgccgga gcgctggttc
    13981 acccccggct tcgccgccgc gcagcccgcc atcgtcgagt gggccgtgca gatggtccgc
    14041 accacggatc ccgggtgcta catcgccgcc tgcgaggcgc tcgcggcgtt cgacatccgc
    14101 ggcgccctgg gccggatcgg cgcgcccacc ctggtgctgg tcggggcgga ggaccaggtc
    14161 accgggcccg ccgaggcccg cacgctggtc gccgggatac cggacgcccg cctggcgctc
    14221 gtccccgggg cctcgcacct cgcgccggtc gagcagcccg ccgccgtcag cgacctgctg
    14281 ctgatgcact tctccacctc ctggcagcag gacacgtcgg ccgcgatccc cgtactgccg
    14341 atcgtccccg ggcccgcgaa gcccgccgcc ccgttcgccc cggtggccga gatcgccccg
    14401 gccgccccga cgcccgagac ctccgctgcg acgccggacg cccggcacga gcagggtacg
    14461 aaggtacgcc gggaggtgct gggcgacgcc catgtcgacg cggtgaacgc ctccgccgac
    14521 ggattcaccg aggacttcca ggagctggtc acccggtacg cctggggcga ggtctggagc
    14581 cgggacggac tcgaccgccg cacccgcagc tgcatcacgc tcaccgcgct cgtcgcctcc
    14641 ggccacctgg agggcctcgc cgcgcacacc cgggccgccc tgcgcaacgg cctgacgccc
    14701 gccgagatca aggaagtcct gctccagacc gccgtctact gcggactccc ggccgccggg
    14761 gccgccttcg ccgtcgcgca gcaggtgatc caggaggaaa ccacgccgcc cgcgtagcag
    14821 gatggggcca tgaacgcatc gcccggggct ctcaccctca ccaagaagac ccactcctgc
    14881 gtccggatcg agaaggaggg gcgggtcctg gtcatcgacc ccggcggctt ctccgaggac
    14941 gacgcggcgc tcggcgccga tgtcgtcctg gtgacgcacg agcacccgga ccacttcaac
    15001 gaggcacggc tgcgggtggg cctggaggcg aacccggcgg ccgagatctg gacgctgcgc
    15061 agcgtggccg agcagctctc ggcggccttt cccgggcgtg tgcacaccgt gggcgagggg
    15121 gacgcgttct ccgccgccgg attcgacgtc accgtgcacg gcgagctgca cgcggtgatc
    15181 cacccggaca tcccgaggat caccaacgtc ggtttcctcg tcgacggttc ggtcttccac
    15241 cccggcgacg cgctcaccgt ccccgaccgc cccgtcgaca ccctcctgct gccggtgatg
    15301 gcgccctgga gcaagatctc cgaggtcatc gactacgtgc gcgaggtcca gccgcgacgc
    15361 gccatcgacg tccacgacgc cctgctgacc gatctggcac ggccgatcta cgacaaccag
    15421 atcggggccc tgggcggcgc ggaccacggc cggctggccc cgggcggtgt caccgagctg
    15481 tgagcccacc ggcgactgtc agtgggagcc gctaggttgg ctgccatgcg catcgccacc
    15541 tataacgtca attcgatcac cgcccggctg ccgaggcttc tggcctggct ggagagcagc
    15601 ggcaccgatg tgctgtgcat ccaggagacc aagtgcacgg cggagcagtt ccccaccgcc
    15661 gccctcgccg agctgggtta cgagtccgcg gtcaacgcca ccggccggtg gaacggggtc
    15721 gcgctgctct cccgcgtcgg cctctccgac gtcgtcaccg ggctgcccga cggcccggac
    15781 tacgacgggg tgcaggagcc gcgcgcgatc tcggcgacgt gcggcccgct gcgcctctgg
    15841 tcggtgtacg tgcccaacgg ccgcgaggtc gagcacgagc actacgcgta caagctgcgc
    15901 tggctggagg ccctgcggaa ggccgtggcg gcggacgccg cgaaggcact gccgttcgcg
    15961 gtcctcggcg acttcaatgt ggccccgacg gacgaggacg tctgggaccc ggcgctgttc
    16021 gccggcgcca cgcatgtgac gcccgccgag cgcgccgccc tcacggccct ggaggcggag
    16081 ggcctgagcg aggtcctgcc ccgccccctc aagtacgacc gcgcctacac cttctgggac
    16141 taccgcgagc tgaggttccc caagaacaag ggcatgcgga tcgacctcac cttcggcaac
    16201 gccccgttcg ccgccgccgt caaggacagc tacgtcgacc gcgaggagcg caagggcaag
    16261 ggcgcgtcgg accacgcccc ggtggtcgtc gacctcgacc tctgaggcgc gatccacggg
    16321 ggcggaggcc gcggcgcgct gacaacccga ggttgacgcc cattgggtgt caacctacgg
    16381 ttgacgcatg acgcagcctc ttcccgccgc accgtccgtg cgcctcgacg acctgatcga
    16441 ggccatcaag aagtccaaca ccgatgccct ggagcagctc tccggcgcgg tcatcgccgc
    16501 cgaccacctc ggcgacgtcg ccgaccatct gatcggccac ttcgtggacc aggcgcgccg
    16561 ctccggcgcc tcctggacgg acatcggccg gagcatgggg gtcacccgcc aggcggccca
    16621 gaagcgcttc gtgcccaaga agggtgacgg cgcctccgac ctggacccga gccagggctt
    16681 cggccgcttc acccagcgcg cccgcaacgt cgtcatggcc gcccacaacg aggcccaggc
    16741 cgcccggcac gccgagatcc tcccggccca cctggtgctc ggcctgctcg ccgagcccga
    16801 atccatcgcg gccggggtcc tcctcggccc ggaggtcacc gcggacgccc tccgtacggc
    16861 ggcgaccgcc gcgctgccgg cggcagccga agaggtgccc gagctgatcc cgtacgacgc
    16921 ggactcccgc aaggtcctgg agctgacctt ccgcgaggcg ctgcggctcg ggcacaacta
    16981 cgtcggcacc gagcacatcc tgctggccct gctggagttc gagggcggat ccggcgtgct
    17041 gagcggcctc ggcgtggaga aggacgccgc ctcggcggcc gtcgaggcgg cggtgaccga
    17101 agcggccgcc gccctgtggc agcagaagtc ctgaccggac agcctccggg gcgcggacgg
    17161 caggttctca gtgcaccgag aacccgccgt ccacgaacac cgactgcccg gtgacgtacg
    17221 cnnnnnnnnn ncagctacgt cgaccgcgag gagcgcaagg gcaagggcgc gtcggaccac
    17281 gccccggtgg tcgtcgacct cgacctctga ggcgcgatcc acgggggcgg aggccgcggc
    17341 gcgctgacaa cccgaggttg acgcccattg ggtgtcaacc tacggttgac gcatgacgca
    17401 gcctcttccc gccgcaccgt ccgtgcgcct cgacgacctg atcgaggcca tcaagaagtc
    17461 caacaccgat gccctggagc agctctccgg cgcggtcatc gccgccgacc acctcggcga
    17521 cgtcgccgac catctgatcg gccacttcgt ggaccaggcg cgccgctccg gcgcctcctg
    17581 gacggacatc ggccggagca tgggggtcac ccgccaggcg gcccagaagc gcttcgtgcc
    17641 caagaagggt gacggcgcct ccgacctgga cccgagccag ggcttcggcc gcttcaccca
    17701 gcgcgcccgc aacgtcgtca tggccgccca caacgaggcc caggccgccc ggcacgccga
    17761 gatcctcccg gcccacctgg tgctcggcct gctcgccgag cccgaatcca tcgcggccgg
    17821 ggtcctcctc ggcccggagg tcaccgcgga cgccctccgt acggcggcga ccgccgcgct
    17881 gccggcggca gccgaagagg tgcccgagct gatcccgtac gacgcggact cccgcaaggt
    17941 cctggagctg accttccgcg aggcgctgcg gctcgggcac aactacgtcg gcaccgagca
    18001 catcctgctg gccctgctgg agttcgaggg cggatccggc gtgctgagcg gcctcggcgt
    18061 ggagaaggac gccgcctcgg cggccgtcga ggcggcggtg accgaagcgg ccgccgccct
    18121 gtggcagcag aagtcctgac cggacagcct ccggggcgcg gacggcaggt tctcagtgca
    18181 ccgagaaccc gccgtccacg aacaccgact gcccggtgac gtacgccgag gagcgccccg
    18241 ccaggaacac cgcggccccc gcgaagtcct ccacgaggcc gttgcggccg accagggtcc
    18301 gggcggcgag cgacgccacc ttctccgggt ccgaggcgag gctccggttc agcggcgtca
    18361 gcacgaaccc gggcaccagg gtgttcacgg tgacgccgtg cggggaccac gcctcggcct
    18421 gggagcgggc cagggactcc aggccgccct tggacacccc gtacgcgccg ctgtccacga
    18481 aggcccggtg cgcctgctgc gaggtgacgt ggatgatccg cccgtagccg cgctcggcca
    18541 tgccgggccc gaagcgctgc cccaacagga acggcgcctt caggttcacc gccatcgtgg
    18601 tgtcccagac gtcctcgccg agctcggcca tcggcgggcg cagattgatc ccggcgcagt
    18661 tcaccaggat gtccggctcc ccgaacgcct gggcggcccc gtccgctccc gcgcgtactc
    18721 cctcggcggt gctcaggtcc gcgctcaccc aggcggcccg gcagccctcg gcggtcagct
    18781 cgtccacggt cgccctcagc tcggcctccc ggcgggccac cacgacgacg cccgcgccgg
    18841 cccgggccag ggcgccggtg atcgcccggc cgatgcctga gctgccgccg gtgaccaccg
    18901 ccacccggcc ttccagcgag aacagttccg aaacgtaagc gtgtgcactc atgtgcgcac
    18961 tttagatatc tgctcggatc cccggccgag gtggggtggg ggatcggtga acgccgcgcg
    19021 ccctgtggtg cggaacctgg ccgggatggg accctagtgg tatgaacatc cctttcttgg
    19081 acaactggcg taagcgtcag ggtggtacgc gttcaggcgc actcgccgcc gccgtcgagg
    19141 cagaccccga cggcgtggcc gaactgctcg ccgaatgcga actgctgcgg gtccgggcgg
    19201 ggcagcacgg actcgaactc gacgacacac ccgcctcgtt ggccgcgctc gaccagctgc
    19261 cgccccgctg gcgcgacgac cccgaggagc ttccctggct cggcaacgac gccggtctct
    19321 acctcggcac cgtgatcgtg cggaccgtcc cgggtgcggc gtgggacgtc tggccgagcg
    19381 gtcagcccgt ggtgcggctg gagtccgggc gggagatcga cgtcgtcgcg gccggtctcg
    19441 actgggcgat ggcgggcagc cccgagctct cccaggtcta cgcggagtcc gccgagaact
    19501 gagccggcgc ccggccgggg gcccgctctc ctcagctaat ccagttaaaa agccttttgc
    19561 gccatttacg cgtgtcgggt gcgaagtccc ttttcgggat ggatagtttg cgctgacctc
    19621 gacacagcga caagtgggta gggcagcgca tggccgtcga tccgttgatc gaactgcggg
    19681 acgtcaacaa acacttcggg gagttgcacg tacttcagga catcaatctc accgtcggcc
    19741 gcggggaggt ggtggtggtc atcggcccct ccggctcggg gaaatccacc ctgtgccggg
    19801 cgatcaaccg gctggagacg atcgagtccg gcagcatcat gatcgacggc agaccccttc
    19861 ccgaggaagg caagggactg gcccagctcc gtgccgaagt cggcatggtc ttccagtcgt
    19921 tcaacctctt cgcccacaag accgtgctgg acaacgtctc gctggcacag ctcaaggtcc
    19981 gcaagcgcaa gaaggacgag gccgaccggc gctcgggcga actgctggag cgggtcggcc
    20041 tggccgccca cgccgacaag ttccccgccc agctctccgg cggtcagcag cagcgcgtgg
    20101 ccatcgcccg tgccctggcc atggatccca aggcgctcct cttcgacgag cccacctcgg
    20161 cgctcgaccc ggagatgatc aacgaggtgc tggaggtcat gcagcagctc gcccgggacg
    20221 gcatgaccat ggtcgtggtc acccacgaga tgggcttcgc gcgctccgcg gccaaccgcg
    20281 tggtgttcat gtccgacggc tgcgtcgtcg aggaccgcac cccggaggac ttcttcacga
    20341 acccttcgag cgaccgcgcc aaggacttcc tgtccaagat cctcaagcac tgaggggagg
    20401 cttccatgtt ccgcacgagg aacacgcgta cgggcagggc cgccgccctg gtggccggtc
    20461 tcctgctcgc cgcactcgcc gcgggctgcg gcaaggacgg cagcccgccg gtcaagggcc
    20521 ccaaggccga ggccctgccg gtgtaccagg tcgacaccgg cttcgaactg cccgactccc
    20581 gcacctggac caaggcgaag aagcgcggct atctggtggt cggcgccaag gaggaccagc
    20641 cgtacctggg ggagaaggac ccggcgagcg ggatctactc cgggttcgac atcgagatcg
    20701 cccggatgat gtcggcctcg ctcggcttcg acccgaagac gatccgcttc cgcacgatcg
    20761 cctccgccaa ccgcgagacg gccctgcaga acggccagat cgactactac gtcggcacct
    20821 acaccatcaa cgacatgcgc aagaagctcg tcggcttcgc cggtccgtac tacatggcgg
    20881 gccagggcct gctggtgcgt accgacgaga acgacatcaa cgggccccag gacctggcgg
    20941 gcaagaccgt ctgctcggcg gccggctcca cgccctacca gcgcatcgcc gccgactatc
    21001 ccaaggcgac gctcgtcgcg tacgacacgt actcgatctg cgtcgacaac ctcctcacct
    21061 tccaggtcga cgccgtcacc accgacgacg cgatcctgct gggcttcgcg gccaaggcgc
    21121 ccgacgagat gaaggtcgtc ggcaagccct tctccgagga gccgtacggc atcggcgtac
    21181 cgcgcaacga caacgcgctg cgcaacgcgc tcaacgacgc gctggaggcc aacgagaaga
    21241 acggcaactg gaagaaggcg tacgaagcga cgctggggct ctccggagcg cccgcgccga
    21301 ccccgccgcc c
//
