LOCUS       NZ_CP096281            22649 bp    DNA     linear   CON 08-JUN-2024
DEFINITION  Streptomyces sp. WAC00303 chromosome.
ACCESSION   NZ_CP096281
VERSION     NZ_CP096281.1
KEYWORDS    RefSeq.
SOURCE      Streptomyces sp. WAC00303
  ORGANISM  Streptomyces sp. WAC00303
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1  (bases 1 to 8548838)
  AUTHORS   Meyer,K.J., Tan,S. and Nodwell,J.R.
  TITLE     Genome Sequence of WAC00303 Direct Submission
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 8548838)
  AUTHORS   Meyer,K.J., Tan,S. and Nodwell,J.R.
  TITLE     Direct Submission
  JOURNAL   Submitted (19-APR-2022) Biochemistry, University of Toronto, 1 Kings
            College Circle 5207, Toronto, ON M5S 1A8, Canada
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: 15-MAR-2022
            Assembly Method                   :: Flye v. 2.8.1
            Assembly Name                     :: WAC00303
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 58.0x
            Sequencing Technology :: Oxford Nanopore; Illumina NextSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_023210535.1-RS_2024_06_08
            Annotation Date                   :: 06/08/2024 05:21:48
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 7,823
            CDSs (total)                      :: 7,731
            Genes (coding)                    :: 7,293
            CDSs (with protein)               :: 7,293
            Genes (RNA)                       :: 92
            rRNAs                             :: 6, 6, 6 (5S, 16S, 23S)
            complete rRNAs                    :: 6, 6, 6 (5S, 16S, 23S)
            tRNAs                             :: 71
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 438
            CDSs (without protein)            :: 438
            Pseudo Genes (ambiguous residues) :: 0 of 438
            Pseudo Genes (frameshifted)       :: 228 of 438
            Pseudo Genes (incomplete)         :: 241 of 438
            Pseudo Genes (internal stop)      :: 26 of 438
            Pseudo Genes (multiple problems)  :: 54 of 438
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 18:23:54
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 5516281
            Orig. end                         :: 5538930
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP096281.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            Bacteria and source DNA available from Justin Nodwell, University
            of Toronto.
FEATURES             Location/Qualifiers
     region          1..22649
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="lanthipeptide-class-iii"
                     /region_number="17"
                     /rules="(micKC and not PKS_KS)"
                     /tool="antismash"
     cand_cluster    1..22649
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(micKC and not PKS_KS)"
                     /kind="single"
                     /product="lanthipeptide-class-iii"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..22649
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:12649](+)"
                     /cutoff="20000"
                     /detection_rule="(micKC and not PKS_KS)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-iii"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..12649
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(micKC and not PKS_KS)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-iii"
                     /protocluster_number="1"
     misc_feature    complement(107..120)
                     /note="TFBS match to ANR, Anaerobic transcriptional
                     regulator, confidence: weak, score: 18.47"
                     /tool="antismash"
     misc_feature    complement(410..423)
                     /note="TFBS match to ANR, Anaerobic transcriptional
                     regulator, confidence: weak, score: 17.99"
                     /tool="antismash"
     misc_feature    complement(831..845)
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence: weak,
                     score: 19.57"
                     /tool="antismash"
     misc_feature    832..845
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 14.69"
                     /tool="antismash"
     gene            985..>1725
                     /locus_tag="MWG59_RS25640"
                     /old_locus_tag="MWG59_25640"
     CDS             985..>1725
                     /GO_function="GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /GO_process="GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Alpha-amylase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007455451.1"
                     /locus_tag="MWG59_RS25640"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MWG59_25640"
                     /product="alpha-amylase family glycosyl hydrolase"
                     /protein_id="WP_248585956.1"
                     /sec_met_domain="Alpha-amylase (E-value: 1.5e-18, bitscore:
                     66.3, seeds: 31, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSSRAARATLAGLLAAGGLTVLAPWTSQATPPGEKTVTATLFEWK
                     YDAVATACTDTLGPAGYGYVEVSPATEHIQGDQWWTSYQPVSYRIAGRLGDRDSFAAMV
                     ESCHAAGVQVVADAVINHMAAGSGTGTGGTSYTKYDYPGTFQDQDFHTCRKDIANYGDR
                     GDVQNCELVGLADLDTGSDAVRTTIAAYLSDLRSLGVDGFRIDAAKHMSADDVAAIKGK
                     TGDPGFWVTEVIHGGGEAVQPEEYT"
     assembly_gap    1726..1735
                     /estimated_length=10
                     /gap_type="within scaffold"
                     /linkage_evidence="paired-ends"
     gene            <1736..2429
                     /locus_tag="MWG59_RS25645"
                     /old_locus_tag="MWG59_25645"
     CDS             <1738..2429
                     /codon_start=2
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018510174.1"
                     /locus_tag="MWG59_RS25645"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MWG59_25645"
                     /product="hypothetical protein"
                     /protein_id="WP_248585957.1"
                     /transl_table=11
                     /translation="TLDSQETVRGAAGSDYNPVSVIGSLFGGERPADPVIPVDEEKLGV
                     ALTDLAGVSGSSNDGTIRFEPNKAVAVPGKPGKTLDAGQSLISVRDAYRAQVQTGQARL
                     VELPVTTSEPTITKTELDRAMKEFAEPAMSGLITIKAGPKEIQFGPARSLPQILSMKPV
                     DGRLVDVYDKQAIDKLLDGVFDGIMAVKGDGKKYQVGADDVAQAMKTALAGKTPAERTV
                     TIDLTGQG"
     misc_feature    complement(2563..2577)
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence: weak,
                     score: 19.57"
                     /tool="antismash"
     misc_feature    2564..2577
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 14.69"
                     /tool="antismash"
     gene            2716..4092
                     /locus_tag="MWG59_RS25650"
                     /old_locus_tag="MWG59_25650"
     CDS             2716..4092
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Alpha-amylase"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Alpha-amylase_C"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1257: Alpha-glucosidase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007455451.1"
                     /locus_tag="MWG59_RS25650"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MWG59_25650"
                     /product="alpha-amylase family protein"
                     /protein_id="WP_248585958.1"
                     /sec_met_domain="Alpha-amylase (E-value: 8.2e-22, bitscore:
                     77.0, seeds: 31, tool: rule-based-clusters)"
                     /sec_met_domain="Alpha-amylase_C (E-value: 2.2e-11,
                     bitscore: 42.8, seeds: 246, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSSRAARATLAGLLAAGGLTVLAPWTSQATPPGEKTVTATLFEWK
                     YDAVATACTDTLGPAGYGYVEVSPATEHIQGDQWWTSYQPVSYRIAGRLGDRDSFAAMV
                     ESCHAAGVQVVADAVINHMAAGSGTGTGGTSYTKYDYPGTFQDQDFHTCRKDIANYGDR
                     GDVQNCELVGLADLDTGSDAVRTTIAAYLSDLRSLGVDGFRIDAAKHMSADDVAAIKGK
                     TGDPGFWVTEVIHGGGEAVQPEEYTSIGDVDEFRYGGHLKSAFQGGGLPGLKSIADGKL
                     AGASARTFVDNWDTERNGSTLTHKDGAAYTLANVFMLASPYGSPNVFSGYTWTDKDAGP
                     PNGGAADCGSGAWTCTHAQQAVTGMVGFHNAVAGAELTDWWDDGSSALAFARAGKGFVA
                     VNNGDAELNRTFTTTLPAGTYCNVVAAAPDSCDGNGTTVADDGTATITVPARGAVALHT
                     "
     assembly_gap    4121..4130
                     /estimated_length=10
                     /gap_type="within scaffold"
                     /linkage_evidence="paired-ends"
     gene            complement(4162..5934)
                     /locus_tag="MWG59_RS25655"
                     /old_locus_tag="MWG59_25655"
     CDS             complement(4162..5934)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012379170.1"
                     /locus_tag="MWG59_RS25655"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MWG59_25655"
                     /product="coagulation factor 5/8 type domain-containing
                     protein"
                     /protein_id="WP_248585959.1"
                     /transl_table=11
                     /translation="MLPPTAPRTRLRTRALGFAALAVAMLMSVPTAQTAFGEEVQAVPG
                     GGDLGPNVHVFDPSTPDIQGKVDEIFKKQESAQFGTDRYALMFKPGTYDDINAQIGFYT
                     QIAGLGLNPNDTTFNGDVTVDAGWFDGNATQNFWRSAENLTLTPVSGTNRWAVSQAAPF
                     RRMHVKGGLNLAPDGYGWASGGYIADSKIDGQVGPYSQQQWYTRDSSVGGWGNGVWNMT
                     FSGVEGAPANSFPEPPYTTLDTTPISREKPFLYLDGDDYKVFVPEKRENARGISWGNGT
                     PAGESIPLDQFYVVKEGADAATINAAVEQGLHLLFTPGVYHIDETINIDRADTVALGLG
                     LATIIPDNGVTAIKVGDVSGVKLAGLLVDAGPVNSETLIEVGPENASADHSANPTSLQD
                     VFVRIGGAGPGKATTSIVVNSDDTIIDHTWVWRADHGEGWGWEANRADYGVRVNGDDVL
                     ATGLFVEHFNKYDVEWYGERGRTIFFQNEKAYDAPNQAAIQNGDTKGYAAYRVDDSVEQ
                     HEGWGMGSYCCYNVDPTIVQEHGFKAPVKPGVKFHSLIVVSLGGNGQYEHVINDVGSPT
                     SGPDTIPSQVVNFP"
     misc_feature    6022..6039
                     /note="TFBS match to ArcA, Repressor of carbon oxidation,
                     confidence: weak, score: 14.51"
                     /tool="antismash"
     misc_feature    6093..6111
                     /note="TFBS match to LexA_variant_3, Repressor of DNA
                     damage response, confidence: weak, score: 19.2"
                     /tool="antismash"
     gene            6236..6739
                     /locus_tag="MWG59_RS25660"
                     /old_locus_tag="MWG59_25660"
     CDS             6236..6739
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007446870.1"
                     /locus_tag="MWG59_RS25660"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MWG59_25660"
                     /product="DUF4265 domain-containing protein"
                     /protein_id="WP_248585960.1"
                     /transl_table=11
                     /translation="MSSPAGPERPPREAGQIKVWFRFVPREGWLPYDTEGLWATRLGPD
                     TARVDNVPFLQDGVAEGETVRFRTDDEGVHWAVGRVADSGNCTVRVLPSPDGPLGRDPR
                     AVHERLAVFGLTGEVFSAEFPLVALTVPGGADLRGVKALLARGRDEGWWHFEVSCVTDA
                     WRAA"
     gene            complement(6882..7466)
                     /locus_tag="MWG59_RS25665"
                     /old_locus_tag="MWG59_25665"
     CDS             complement(6882..7466)
                     /EC_number="2.3.1.-"
                     /GO_function="GO:0016407 - acetyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Mac"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1156: Chloramphenicol acetyltransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018956278.1"
                     /locus_tag="MWG59_RS25665"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MWG59_25665"
                     /product="sugar O-acetyltransferase"
                     /protein_id="WP_248585961.1"
                     /sec_met_domain="Mac (E-value: 5.6e-15, bitscore: 54.1,
                     seeds: 568, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSDNARPSQKEAMLSGELYIADDPELAAEAQHAAVLSERFNATSA
                     ADPEARRAALAELLGELGEGVEVRPPLRVDYGYQTTIGPRTFINFGAVLLDVARIAIGA
                     DVQMGPNVQLLTPTHPIDPEPRRAKWEAAQPITIGDNVWLGGGAIVCPGVTIGENTVVG
                     AGAVVTKDLPANVVAVGNPARVIRKIGETEA"
     gene            complement(7463..8701)
                     /locus_tag="MWG59_RS25670"
                     /old_locus_tag="MWG59_25670"
     CDS             complement(7463..8701)
                     /GO_function="GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1020: major
                     facilitator transporter"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018956279.1"
                     /locus_tag="MWG59_RS25670"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MWG59_25670"
                     /product="MFS transporter"
                     /protein_id="WP_097935361.1"
                     /transl_table=11
                     /translation="MRTYRELFRTPEFTPFFAAVSVQTAAQTATGLALGTLVYTRTGSP
                     LLSALAMFGPSLAQVAGALTLLSAADRLPPRAALAALALLSAGAACVQAVPGLPLWAAF
                     AVLLVVGAASSPGGGVRYGLLNEIVPPGGFLLGRSVLNMTGGAMQICGFAVGGLLVTVF
                     STRGTLLIGAGLYVVAAAVTRFGLTARPPRATGRPSVRETRRTNALLWSSTPRRYVFLA
                     LWVPNGLVVGAESLYVAYAPGHAGLLFAGGALGMLAGDTLVGRFVTARWRARLGAPLRL
                     LLAAPYLLFALRPELPLALAAVVLASVGFAASLLLQERLMALTPQELSGQALGLSSSGM
                     LAMQGVGAAVAGGIAQLTSPATGMVAVAGLSVAVTLALAPGLRDRSGGVGGRLPVADGS
                     PRASRTPRTEETT"
     gene            8813..9790
                     /locus_tag="MWG59_RS25675"
                     /old_locus_tag="MWG59_25675"
     CDS             8813..9790
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015611151.1"
                     /locus_tag="MWG59_RS25675"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MWG59_25675"
                     /product="winged helix-turn-helix domain-containing
                     protein"
                     /protein_id="WP_248585962.1"
                     /transl_table=11
                     /translation="MGWWQVGADTLANSRFVVSPLAEAVASLLVLERVTAAHPGERAWL
                     ETHLPAYRRWKADDPVSALVIGAALAPRWIADFIVPVPDPAPPGQAPPSFADELTPVRA
                     TPPDRARADLAEAVRGPLPAALDRDDLARRAADALEWVWTHTVLPDWPRRRRILEADVM
                     ARSAQLGRGGWVDALNGMRPGIRWLGDSRLQINTHDNPPRELDGVQLLFVPVTPYQSWV
                     CWDIPRRYGLVYPCSGALAEAGRIPVPAALGALIGPARAAVLLLLASPLSTTQLVALTG
                     QGLGSVGRHLRILLEAGLVRRRRAGRSVLYFRTEAGDVLVHGAG"
     misc_feature    9942..9962
                     /note="TFBS match to NrtR, NAD synthesis repressor,
                     confidence: weak, score: 18.6"
                     /tool="antismash"
     misc_feature    complement(9953..9965)
                     /note="TFBS match to MatP, Cell cycle regulator,
                     confidence: weak, score: 19.27"
                     /tool="antismash"
     gene            10001..12649
                     /gene="lanKC"
                     /locus_tag="MWG59_RS25680"
                     /old_locus_tag="MWG59_25680"
     CDS             10001..12649
                     /GO_function="GO:0004672 - protein kinase activity
                     [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_process="GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /GO_process="GO:0006468 - protein phosphorylation [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="lanKC"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-iii: micKC"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Pkinase"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) LANC_like"
                     /gene_functions="regulatory (smcogs) SMCOG1030:
                     serine/threonine protein kinase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007446862.1"
                     /locus_tag="MWG59_RS25680"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MWG59_25680"
                     /product="class III lanthionine synthetase LanKC"
                     /protein_id="WP_248585963.1"
                     /sec_met_domain="micKC (E-value: 5.4e-233, bitscore: 774.5,
                     seeds: 18, tool: rule-based-clusters)"
                     /sec_met_domain="Pkinase (E-value: 1e-11, bitscore: 43.6,
                     seeds: 54, tool: rule-based-clusters)"
                     /sec_met_domain="LANC_like (E-value: 1.6e-07, bitscore:
                     29.3, seeds: 47, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNPEYAAYCQADRRFYDAPHRSPGPGGAADEERSFYAPLRGAVPD
                     GWTRSRRGDWLAYSPDGLRLPPQGWKIHVSAALDNAASVLERVVAHCLEHRLAFKCVPN
                     AGLLALRNAKYADRAGSGKFITVYPPSDEAFPEVCTALTHLLEGEHGPYILSDLRCGNG
                     PVHTRYGAFAARFCSGPDGRPVPAVADPQGRLVPDDRGPSFRVPSWVTPPGFLMPHLEA
                     RAAVGLADLPYTVEKALHFSNGGGVYLGRDTRTGEQVVLKEARPYAGLAADGADAVARL
                     ERERAALEQLDGLDCVPAVRDVLEVGDHHFLVLQYIPGTTLNTVFARRFPLARQHPSPE
                     LLAEHAAWAAELYGQVERAVEAVHDRGIVISDLHMSNVMVDEENGRIVLLDFEAASPAA
                     ERRRQIVANPAFVAPPDRRGADIDRYALACLRLALYLPLTTLFGIDRTKAAGLARDIAR
                     VFPVTEETLRPAVAEILRDTGEPARRVAPASLRAPSPAPVPDPGDWPRSRDALVRAITA
                     SCTPEREDRCFPGDIAQFATATGGQSFAYGAAGVLYALHETGAPPCEEAEDWLLRHAKD
                     PASGSPLGFYDGLTGIAWTLHRIGRTAEAADLLRIILDQPLQGLAPGLHNGYAGIGLAL
                     DDLARTASATDAPALSAAAARCTALAVRALVDGPPSPRTGLLHGASGIALLLVRRYATT
                     GDAALLDLAATALRRDLERCRAGDDGELLVVEGKRLMPYLGSGSAGIAAVIDAYLAHRP
                     DPALEAAGRALLPAALSAFYVQPGLLRGSAGLLMHLAATPLCDEAGRQRAVARHTDLLG
                     SHALAYGDGLAFPGEQLMRLSMDLATGTAGALLALGAALGGSTGLPFLPAAPAAPPGRA
                     SGPTDRPRQGS"
     gene            12695..12826
                     /locus_tag="MWG59_RS25685"
                     /old_locus_tag="MWG59_25685"
     CDS             12695..12826
                     /codon_start=1
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015611153.1"
                     /locus_tag="MWG59_RS25685"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MWG59_25685"
                     /product="SapB/AmfS family lanthipeptide"
                     /protein_id="WP_003966507.1"
                     /transl_table=11
                     /translation="MALLDLQAMDTPAEDSFGELATGSQVSLLVCEYSSLSVVLCTP"
     CDS_motif       12695..12760
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence: MALLDLQAMDTPAEDSFGELAT"
                     /locus_tag="MWG59_RS25685_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       12761..12826
                     /prepeptide="core"
                     /locus_tag="MWG59_RS25685_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class III"
                     /score="31.80"
                     /molecular_weight="2076.4"
                     /monoisotopic_mass="2075.1"
                     /core_sequence="GSQVSLLVCEYSSLSVVLCTP"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MALLDLQAMDTPAEDSFGELAT"
                     /leader_location="[12694:12760](+)"
                     /alternative_weights="2094.4"
                     /alternative_weights="2112.4"
                     /alternative_weights="2130.5"
                     /alternative_weights="2148.5"
     assembly_gap    12851..12860
                     /estimated_length=10
                     /gap_type="within scaffold"
                     /linkage_evidence="paired-ends"
     gene            12897..14666
                     /locus_tag="MWG59_RS25690"
                     /old_locus_tag="MWG59_25690"
     CDS             12897..14666
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1288: ABC
                     transporter related protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007446857.1"
                     /locus_tag="MWG59_RS25690"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MWG59_25690"
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_248587307.1"
                     /transl_table=11
                     /translation="MRLHPRPGTESGTRRLARQYPAALLGLLLCSTGGALAALALPAAL
                     GHTVDRLVAGGPVPWSLLLLCAALTLAETGFDAAAAVTGTSTTARLTASLRTRTAARVL
                     AAEPRRALALPTGDLTARLTARTADAASAPVTAAGAVSGVLLPLGALVGLLLIDVWTAA
                     ALLLGAPLLVALLRAFTRRTADAGADYQRAQSLIAHRLTEALDGADTIRAARTGAHEHR
                     RVLEPLTALAEHGRRTWAVYGRAVGRSGLLLPLLMLLVLAVAGLRLHAGAIGVGDLVAA
                     SRYASLAVGIGALTGALGALARSRAAARSLEPLLNLAPFPHRGLGPVPDAPGHLELRDV
                     GVEQDGGPLLTGVHLTVPGGTSLAVVGRSGSGKSVLAAVAGRLLDPDTGSVLLDGVPMD
                     GMEPARLRREVAYAFARPALPGTTVEDTIAYGPWTASPEAVRDAARAARADGFLALLPY
                     GYATPVADAPLSGGERQRLGLARAFAHPGRLMILDDALSSLDTVTEHHVRRALDERAGH
                     CTRVIVAHRLSSAARADRVAWLEDGRIRATGRHDELWSDPDYRAVFRTDVPAEGSVPAS
                     RTPVTPAAGAETR"
     gene            14885..16735
                     /locus_tag="MWG59_RS25695"
                     /old_locus_tag="MWG59_25695"
     CDS             14885..16735
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1288: ABC
                     transporter related protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010061641.1"
                     /locus_tag="MWG59_RS25695"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MWG59_25695"
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_248587308.1"
                     /transl_table=11
                     /translation="MRRVGREARPFLRARTGVVLRLAGWSLLEFAQTFLGGFGVARALD
                     DGFLAGRPPTGLLWLAVAAVAVLPSVPAARGVFGRLADLVEPLRDGLVRRAVSRALSGA
                     LDRSGDVSTRSLSQVTHQSEIARDGWAGLVLTLRSFVFTAAGAVTGLLALSPALLLIVL
                     PPLVLGSALFLGTLPPMAARQRDYLAADEAYAAHAGWLAASVRDIAAAGAAERTVAESR
                     ALAEAQLAASRSLARWSGVRVLALAVCGRFPPLLLLLGAPWLLRNGLTPGALVGALTYL
                     TQALAPAVQALMTMLGTVGGRLVVVLDRFTDAPPPPAEDPPPSRDAAPPPRGTPVAELH
                     EVSFAYGPGAHPVLDGLSLTIGAGEHLAVVGPSGSGKSTLAAVLAGTERPTGGAVRWRG
                     RPVRPADATSVRVLLPQHAYVFSGSLRDNLRYHHPDARDREIAAMADALGLEALLSRLG
                     SLDAAVEPDRLSQGERQLVALGRAYLAAPPLLILDEATSRLDPAAETRAELAFGALPGA
                     LVVVAHRLSSARRAGRILVMDGPRTQCGTPDELLRSCALYRDLAGLWEPEDAGEPGETR
                     ESEEPGEQDEAGEPEEPGGAVGIGRGKGRAIRSTPPPSPV"
     gene            complement(16704..17309)
                     /locus_tag="MWG59_RS25700"
                     /old_locus_tag="MWG59_25700"
     CDS             complement(16704..17309)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1016: LuxR family
                     DNA-binding response regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006127364.1"
                     /locus_tag="MWG59_RS25700"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MWG59_25700"
                     /product="response regulator transcription factor"
                     /protein_id="WP_050360577.1"
                     /transl_table=11
                     /translation="MTTVLLVHTVPLWRASLASLLGTGRGIEVRTAEHGAIRAALSGPC
                     PDVLLTDLECPGALDVLDEVKTMTAPHGGPCPLAVLTRSDRPSGLRRAFEAGALGYIDK
                     YRPVDDLSEVMHKLADGGRHIDESLAFSLLQVADMPLSPRELSVLSMAEGGDTVAGIAG
                     RLHLTPGTVRNYLAAAIRKSGARNRLDAIRRAKEAGWI"
     misc_feature    complement(16887..16889)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     misc_feature    17384..17401
                     /note="TFBS match to HipB, Bacterial antitoxin HipB,
                     confidence: weak, score: 23.05"
                     /tool="antismash"
     misc_feature    complement(17396..17409)
                     /note="TFBS match to ArgR, Regulator of arginine
                     biosynthesis genes, confidence: weak, score: 16.91"
                     /tool="antismash"
     gene            complement(17580..18461)
                     /locus_tag="MWG59_RS25705"
                     /old_locus_tag="MWG59_25705"
     CDS             complement(17580..18461)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018956285.1"
                     /locus_tag="MWG59_RS25705"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MWG59_25705"
                     /product="transglutaminase-like domain-containing protein"
                     /protein_id="WP_097935365.1"
                     /transl_table=11
                     /translation="MSALDSGTAERRRQFAEEARSERPDLALLCLLLGAEAGPVGPAEV
                     RPVTPGEAVPDAYGIDAAQIELDRLAGLLPYGSRSPAAWASALAELLGGRCGFGGSSVD
                     YQRLDSSLLQQVLRRRRGLPILLSVVWIEVARRAGAPVYGVALPGHFVVGFGDREHPVL
                     ADPFAGGAPLTGQDAELLVTGATGAALEPSMMTPARPLEIVLRILNNVRAWAAARPERT
                     DVALWAVELSLLLPSHPARLRFERAQLLVQRGEFLRGAAEMEEYAEILDGIEPTTAENI
                     RRKAHAARALLN"
     gene            complement(18538..19557)
                     /locus_tag="MWG59_RS25710"
                     /old_locus_tag="MWG59_25710"
     CDS             complement(18538..19557)
                     /GO_function="GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010061638.1"
                     /locus_tag="MWG59_RS25710"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MWG59_25710"
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="WP_248585964.1"
                     /transl_table=11
                     /translation="MEFTIGGRLEVRITPADVGKRVSVRRRTDGGGTGAEFTDVVGVLT
                     SWDNGVLSITRKSGESVHIVESSVVAGKVVPAAPARRRGPAASFGELASVTARAWQPVE
                     SEALGDWRLRAAGGFTRRANSALPLGDPGLPVGEALGRVRDWYEERGLPAYVQTATGAE
                     GAQELLCAELERHGWRREVSAEVRIAALAPVGDLEADVRAVRLTREPDAAWLARYQRFS
                     TPGPHVLRVLGSGPSVWFATVPVDTGGADADPDAPPAAIGRCVVDGRWAGFMAVEVAPE
                     QRRRGLATTVMAALARRALDEGASAAWLQVEEDNEGARALYDGMGFAAHHRYHHYRSA"
     gene            19675..19995
                     /gene="fdxA"
                     /locus_tag="MWG59_RS25715"
                     /old_locus_tag="MWG59_25715"
     CDS             19675..19995
                     /GO_function="GO:0009055 - electron transfer activity
                     [Evidence IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="fdxA"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004950253.1"
                     /locus_tag="MWG59_RS25715"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MWG59_25715"
                     /product="ferredoxin"
                     /protein_id="WP_007446848.1"
                     /transl_table=11
                     /translation="MTYVIAQPCVDVKDKACIEECPVDCIYEGQRSLYIHPDECVDCGA
                     CEPVCPVEAIFYEDDTPEEWKDYYKANVEFFDDLGSPGGASKLGLIERDHAFIAGLPPQ
                     NQ"
     gene            20164..21258
                     /locus_tag="MWG59_RS25720"
                     /old_locus_tag="MWG59_25720"
     CDS             20164..21258
                     /EC_number="2.6.1.17"
                     /EC_number="2.6.1.79"
                     /NRPS_PKS="Domain: Aminotran_1_2 (29-363). E-value:
                     5.3e-45. Score: 146.0. Matches aSDomain:
                     nrpspksdomains_MWG59_RS25720_Aminotran_1_2.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Aminotran_1_2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1019: aminotransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010984558.1"
                     /locus_tag="MWG59_RS25720"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MWG59_25720"
                     /product="bifunctional succinyldiaminopimelate
                     transaminase/glutamate-prephenate aminotransferase"
                     /protein_id="WP_097935367.1"
                     /sec_met_domain="Aminotran_1_2 (E-value: 6.6e-43, bitscore:
                     146.1, seeds: 48, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSAVSSRLPVFPWDKLAPYKSTAQAHPDGIVDLSVGTPVDPVPEL
                     IQRALVAAADSPGYPTVWGTEALRDALTGWVERRLGAVGVTHANVLPVVGSKELVAWLP
                     TQLGLGAGDKVAYPRLAYPTYEVGARLCGAEPVVYDDPTELDPTGLKLLWLNSPSNPTG
                     KVLSKDELTRIVAWAREHGVLVFSDECYLELGWDAEPVSVLHPDVCGGHYDGIVAVHSL
                     SKRSNLAGYRAAFIAGDAAVLGELLLIRKHGGMMTPAPVQAAAVAALGDDVHVSEQRAR
                     YADRRLALRAALEAHGFRIEHSEASLYLWATRDEPCWETVAYLAQLGILVAPGDFYGPA
                     GARFVRVAFTATDERVAAAVKRLS"
     aSDomain        20251..21252
                     /aSDomain="Aminotran_1_2"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_MWG59_RS25720_Aminotran_1_2.1"
                     /evalue="5.30E-45"
                     /label="MWG59_RS25720_Aminotran_1_2.1"
                     /locus_tag="MWG59_RS25720"
                     /protein_end="363"
                     /protein_start="29"
                     /score="146.0"
                     /tool="antismash"
                     /translation="IVDLSVGTPVDPVPELIQRALVAAADSPGYPTVWGTEALRDALTG
                     WVERRLGAVGVTHANVLPVVGSKELVAWLPTQLGLGAGDKVAYPRLAYPTYEVGARLCG
                     AEPVVYDDPTELDPTGLKLLWLNSPSNPTGKVLSKDELTRIVAWAREHGVLVFSDECYL
                     ELGWDAEPVSVLHPDVCGGHYDGIVAVHSLSKRSNLAGYRAAFIAGDAAVLGELLLIRK
                     HGGMMTPAPVQAAAVAALGDDVHVSEQRARYADRRLALRAALEAHGFRIEHSEASLYLW
                     ATRDEPCWETVAYLAQLGILVAPGDFYGPAGARFVRVAFTATDERVAAAVKRL"
     gene            complement(21354..21837)
                     /locus_tag="MWG59_RS25725"
                     /old_locus_tag="MWG59_25725"
                     /pseudo=""
     CDS             complement(21354..21837)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007446843.1"
                     /locus_tag="MWG59_RS25725"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /old_locus_tag="MWG59_25725"
                     /product="ATP-binding protein"
                     /pseudo=""
                     /transl_table=11
                     /translation="MSLPLTRRIARAALLIAAGAAPVVGAAGAASAADLPATPDLGGLT
                     ALDGAGLGNTVDSAVQQGTQAVSDTGGRLVGTALPAAGKTVGKSAGVAVPAAQETMRPG
                     RGQRGPGRGRRGRGSRRRPADRRARRRSPHGRARRRPAHRLPDQGRPPAGRSADRRL"
     misc_feature    21947..21962
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: weak, score: 17.37"
                     /tool="antismash"
     misc_feature    complement(22009..22023)
                     /note="TFBS match to IolR, Regulator of the inositol
                     catabolism, confidence: medium, score: 18.11"
                     /tool="antismash"
ORIGIN
        1 tctcaccctg gacagtcagg agaccgtgcg cggcgcggcg ggcagcgact acaaccccgt
       61 ctcggtgatc ggttcgctgt tcggcgggga acgtcccgcc gacccggtga tcccggtcga
      121 cgaggagaag ctcggtgtgg cgctgaccga tctggcgggc gtctccggct cgtccaacga
      181 cggcacgatc cgcttcgagc cgaacaaggc cgtggcggtg ccgggcaagc cgggcaagac
      241 gctggacgcc ggccagtccc tgatctcggt ccgggacgcc taccgcgccc aggtgcagac
      301 cgggcaggcc cggctggtcg aactccccgt caccaccagc gagcccacca tcaccaagac
      361 cgaactggac cgggcgatga aggagttcgc cgagcccgcg atgtccggcc tgatcaccat
      421 caaggccggt cccaaggaga tccagttcgg cccggcccgg tcgctgccgc agatcctctc
      481 catgaagccc gtggacggcc gactggtcga cgtctacgac aagcaggcga tcgacaagct
      541 cctggacggc gtcttcgacg gcatcatggc ggtcaagggc gacggcaaga agtaccaggt
      601 cggcgcggac gacgtggccc aggcgatgaa gaccgccctg gccgggaaga cccccgccga
      661 gcgcacggtc accatcgacc tgaccggcca gggctgacgc ccggaccgga cagcagctcc
      721 acccctccgc ccccgcccgg gaacgtatcc ggccgggggc ggagccgtcg gcgggcgggt
      781 tccgcgccgg ttccgggcgg ggcttctccc caacttcccc atctcgtaag aactttcaga
      841 aacaacctgg aaaccgttgc agacgtcttg acgtgtccat ccccgaacgg caggctccga
      901 actcccccca cggcagccag gcgcgtggct gcccacgccg ggcaacgggc gaacgccccg
      961 tacccgcgac cgaaggagcc gcaattgagt tcccgcgccg cacgcgcaac cctggcgggc
     1021 ctgctcgccg ccggtggcct cacggtcctc gccccctgga cctcccaggc gaccccaccg
     1081 ggcgagaaga ccgtcaccgc caccctcttc gagtggaagt acgacgcggt ggccaccgcc
     1141 tgcaccgaca ccctgggccc ggccggctac ggctacgtcg aggtctcgcc cgccaccgag
     1201 cacatccagg gcgaccagtg gtggacctcg taccagccgg tcagctaccg gatcgcgggc
     1261 cgtctcggtg accgggactc cttcgccgcg atggtggaga gctgccacgc ggccggggtc
     1321 caggtcgtgg cggacgccgt gatcaaccac atggccgccg gctccggcac cgggacgggc
     1381 ggcacgtcgt acaccaagta cgactacccc ggcacgttcc aggaccagga cttccacacc
     1441 tgccgcaagg acatcgcgaa ctacggcgac cgcggagacg tccagaactg cgaactggtc
     1501 ggcctcgcgg acctggacac cggcagcgac gccgtacgca cgacgatcgc cgcctacctc
     1561 tccgacctcc gctccctggg cgtcgacggc ttccgcatcg acgccgccaa gcacatgtcc
     1621 gccgacgacg tcgccgcgat caaggggaag acgggggacc cggggttctg ggtcaccgag
     1681 gtcatccacg gcgggggaga ggcggtccag ccggaggagt acaccnnnnn nnnnncaccc
     1741 tggacagtca ggagaccgtg cgcggcgcgg cgggcagcga ctacaacccc gtctcggtga
     1801 tcggttcgct gttcggcggg gaacgtcccg ccgacccggt gatcccggtc gacgaggaga
     1861 agctcggtgt ggcgctgacc gatctggcgg gcgtctccgg ctcgtccaac gacggcacga
     1921 tccgcttcga gccgaacaag gccgtggcgg tgccgggcaa gccgggcaag acgctggacg
     1981 ccggccagtc cctgatctcg gtccgggacg cctaccgcgc ccaggtgcag accgggcagg
     2041 cccggctggt cgaactcccc gtcaccacca gcgagcccac catcaccaag accgaactgg
     2101 accgggcgat gaaggagttc gccgagcccg cgatgtccgg cctgatcacc atcaaggccg
     2161 gtcccaagga gatccagttc ggcccggccc ggtcgctgcc gcagatcctc tccatgaagc
     2221 ccgtggacgg ccgactggtc gacgtctacg acaagcaggc gatcgacaag ctcctggacg
     2281 gcgtcttcga cggcatcatg gcggtcaagg gcgacggcaa gaagtaccag gtcggcgcgg
     2341 acgacgtggc ccaggcgatg aagaccgccc tggccgggaa gacccccgcc gagcgcacgg
     2401 tcaccatcga cctgaccggc cagggctgac gcccggaccg gacagcagct ccacccctcc
     2461 gcccccgccc gggaacgtat ccggccgggg gcggagccgt cggcgggcgg gttccgcgcc
     2521 ggttccgggc ggggcttctc cccaacttcc ccatctcgta agaactttca gaaacaacct
     2581 ggaaaccgtt gcagacgtct tgacgtgtcc atccccgaac ggcaggctcc gaactccccc
     2641 acggcagcca ggcgcgtggc tgcccacgcc gggcaacggg cgaacgcccc gtacccgcga
     2701 ccgaaggagc cgcaattgag ttcccgcgcc gcacgcgcaa ccctggcggg cctgctcgcc
     2761 gccggtggcc tcacggtcct cgccccctgg acctcccagg cgaccccacc gggcgagaag
     2821 accgtcaccg ccaccctctt cgagtggaag tacgacgcgg tggccaccgc ctgcaccgac
     2881 accctgggcc cggccggcta cggctacgtc gaggtctcgc ccgccaccga gcacatccag
     2941 ggcgaccagt ggtggacctc gtaccagccg gtcagctacc ggatcgcggg ccgtctcggt
     3001 gaccgggact ccttcgccgc gatggtggag agctgccacg cggccggggt ccaggtcgtg
     3061 gcggacgccg tgatcaacca catggccgcc ggctccggca ccgggacggg cggcacgtcg
     3121 tacaccaagt acgactaccc cggcacgttc caggaccagg acttccacac ctgccgcaag
     3181 gacatcgcga actacggcga ccgcggagac gtccagaact gcgaactggt cggcctcgcg
     3241 gacctggaca ccggcagcga cgccgtacgc acgacgatcg ccgcctacct ctccgacctc
     3301 cgctccctgg gcgtcgacgg cttccgcatc gacgccgcca agcacatgtc cgccgacgac
     3361 gtcgccgcga tcaaggggaa gacgggggac ccggggttct gggtcaccga ggtcatccac
     3421 ggcgggggag aggcggtcca gccggaggag tacacctcga tcggggacgt cgacgagttc
     3481 cgttacggcg gccacctcaa gtccgccttc cagggcggcg gcctgcccgg cctgaagtcg
     3541 atcgccgacg gcaaactggc cggcgcctcc gcccgtacgt tcgtcgacaa ctgggacacc
     3601 gagcgcaacg gctccaccct cacccacaag gacggcgccg cctacaccct ggccaacgtc
     3661 ttcatgctgg cctcgcccta cggctccccg aacgtcttct ccggctacac ctggaccgac
     3721 aaggacgccg gcccgccgaa cggcggcgcg gccgactgcg gctccggcgc gtggacctgc
     3781 acgcacgccc agcaggcggt caccggcatg gtcggcttcc acaacgccgt cgcgggcgcg
     3841 gagctgaccg actggtggga cgacggctcc tccgccctcg ccttcgcccg cgcgggcaag
     3901 ggcttcgtcg ccgtcaacaa cggcgacgcg gagctgaacc gcaccttcac gacgacgctg
     3961 ccggcgggca catactgcaa tgtggtcgcc gccgcccccg actcctgcga cggcaacggg
     4021 accacggtcg cggacgacgg cacggcgacg atcacggtcc cggcgcgcgg agcggtggcg
     4081 ctgcacacct gagggctgtc tcgtggacag cggagcgggg nnnnnnnnnn ccccgctccc
     4141 gtacgactcc cgcgtcgggg gctacgggaa gttcacgacc tgggagggga tcgtgtccgg
     4201 gccggacgtg ggggatccga cgtcgttgat gacgtgctcg tactggccgt tgccgccgag
     4261 cgagacgacg atcaggctgt ggaacttcac gccgggcttc accggtgcct tgaagccgtg
     4321 ttcctgcacg atggtcgggt cgacgttgta gcagcagtag ctgcccatgc cccagccctc
     4381 gtgctgttcg accgagtcgt cgacgcggta ggcggcgtag cccttggtgt cgccgttctg
     4441 gatggcggcc tggttcgggg cgtcgtaggc cttctcgttc tggaagaaga tcgtgcggcc
     4501 gcgttcgccg taccactcca cgtcgtactt gttgaagtgc tcgacgaaca ggccggtggc
     4561 caggacgtcg tcgccgttga cgcggacgcc gtagtcggcc cggttggcct cccagcccca
     4621 gccctcaccg tggtcggcac gccacaccca ggtgtggtcg atgatcgtgt cgtcgctgtt
     4681 gacgacgatg ctggtggtcg ccttgccggg acccgcgccg ccgatccgta cgaacacgtc
     4741 ctggagcgag gtcgggttcg ccgagtggtc cgccgaggcg ttctcggggc cgacctcgat
     4801 cagggtctcc gagttcaccg gacccgcgtc gaccaggagg cccgcgagct tcacaccgga
     4861 cacgtcaccg accttgatcg cggtcacccc gttgtccggg atgatcgtgg ccaggccgag
     4921 gccgagggcc acggtgtccg cgcggtcgat gttgatcgtc tcgtcgatgt ggtagacgcc
     4981 gggcgtgaac agcaggtgca ggccctgctc cacggccgcg ttgatggtgg cggcgtccgc
     5041 cccctccttc acgacgtaga actggtccag cggaatcgac tcgcccgccg gcgttccgtt
     5101 gccccaggag atgccgcgcg cgttctcgcg cttctccggg acgaagacct tgtagtcgtc
     5161 gccgtcgagg tagaggaacg gcttctcgcg ggagatgggc gtggtgtcca gggtggtgta
     5221 cggcggctcc gggaagctgt tggccggggc gccctcgaca cccgagaacg tcatgttcca
     5281 gacgccgttg ccccagccgc ccaccgagct gtcgcgggtg taccactgct gctgggagta
     5341 cgggccgacc tggccgtcga tcttgctgtc ggcgatgtag ccgccgctgg cccagccgta
     5401 cccgtcgggg gcgaggttga gtccgccctt gacgtgcatc cggcggaacg gggccgcctg
     5461 ggagaccgcc cagcggttgg tgccggagac cggggtgagg gtcaggttct ccgccgaacg
     5521 ccagaagttc tgcgtcgcgt tgccgtcgaa ccagcccgcg tccacggtca catcaccgtt
     5581 gaacgtggtg tcgttcgggt tcagcccgag acccgcgatc tgcgtgtaga aaccgatctg
     5641 cgcgttgatg tcgtcgtacg tgcccggctt gaacatcagc gcgtagcggt cggtgccgaa
     5701 ctgcgcggac tcctgcttct tgaagatctc gtcgaccttg ccctggatgt cgggcgtgga
     5761 cgggtcgaag acatggacgt tggggccgag gtcgccgccg cccggcaccg cctggacctc
     5821 ctcgccgaag gcggtctgtg cggtgggtac ggacatgagc atcgccacgg cgagcgcggc
     5881 gaatccgagg gcccgggtgc ggaggcgggt gcgtggtgcg gtggggggga gcatgcatga
     5941 ggtacgtctc ctgggtcgtg gtacgtgtgc acgacgagcg gacgggagag ctttgggggg
     6001 aggctgcggg agagcgctct ctcgtaacgg tgatgtttcc cccgtgggcc tgtacgcgtc
     6061 aagaggtgtg catcaggagc ctcaggagat gccactggat ccaacaactg gcgtcaggtg
     6121 ttggggaatt ggcggttgcg gcgtggtggg gcggcctctg gcttcagaag ctgacgtcgt
     6181 gcctggtcgt ggcggtggac aggcgggcgc gccgggcgcg ggggaccatg gggccatgag
     6241 ttcccccgcc ggtccggaac gcccgccccg cgaagccggt cagatcaagg tctggttccg
     6301 cttcgtcccg cgcgagggct ggctgcccta cgacaccgag gggttgtggg cgacgcggct
     6361 cggcccggac accgcgcggg tggacaacgt gcccttcctc caggacgggg tcgccgaggg
     6421 cgagaccgta cggttccgca cggacgacga aggggtccac tgggccgtcg gccgcgtggc
     6481 cgactcgggc aactgcaccg tacgggtgct gccgtcgccg gacggaccgc tcgggcgcga
     6541 cccccgggcc gtgcacgagc ggctcgccgt cttcgggctc acgggcgagg tcttcagcgc
     6601 ggagttcccg ctggtcgccc tgaccgtgcc gggcggcgcg gacctgcgcg gggtcaaggc
     6661 gctgctcgcc cgcggccggg acgagggctg gtggcacttc gaggtctcgt gcgtcaccga
     6721 cgcctggcgg gccgcgtagc gcgcggggcg ctgggcgggg cggggcggcc cgcgccaaac
     6781 cggagtgccg cggtcggcgg gctgcccgca cccgaggcgc tgcgcccggc gggctgcagg
     6841 aaacccgggt gccgcgccga cgggccgcgg acctcggggt gtcacgcctc cgtctcgccg
     6901 atcttccgga tcacccgggc cggattgccg accgccacca cgttcgccgg caggtccttc
     6961 gtgacgaccg cccccgcccc gaccaccgtg ttctcgccga tggtcacccc ggggcagacg
     7021 atcgccccgc cgcccagcca gacgttgtcg ccgatggtga tcggctgcgc ggcctcccac
     7081 ttggcgcggc gcggctcggg gtcgatcggg tgggtcgggg tgagcagctg gacgttcggg
     7141 cccatctgga cgtccgcgcc gatggcgatg cgggcgacgt ccaggaggac cgcgccgaag
     7201 ttgatgaagg tccgggggcc gatggtcgtc tggtagccgt agtcgacccg cagcggcggc
     7261 cgcacctcca cgccctcgcc cagctcgccg aggagttcgg ccagggcggc acgccgggcc
     7321 tcggggtcgg cggccgaggt ggcgttgaaa cgctcgctga gcacggccgc gtgctgcgcc
     7381 tccgccgcca gttcggggtc gtcggcgatg tagagctcgc cggagagcat ggcttccttc
     7441 tggctgggcc tggcgttgtc gctcatgtgg tctcttccgt gcggggtgta cgggacgctc
     7501 gtggtgatcc gtccgccacc ggcagtctgc ccccgacgcc cccggaccgg tcacgcagtc
     7561 ccggggccag cgccagtgtc accgccaccg agagcccggc gaccgccacc atgcccgtgg
     7621 ccggggaggt cagctgggcg ataccgcccg ccacggccgc ccccacaccc tgcatcgcga
     7681 gcatccccga ggagctgagc ccgagcgcct ggccgctcag ctcctgcggg gtgagggcca
     7741 tcagccgttc ctggagcagc agactcgcgg cgaagcccac gctcgccagg acgaccgccg
     7801 ccagcgcgag gggcagctcc gggcgcagtg cgaagagcag atagggcgcg gcgagcagca
     7861 gccggagcgg ggccccgagc cgcgcccgcc accgtgccgt gacgaaccgc ccgaccagtg
     7921 tgtccccggc cagcatgccc agggccccgc cggcgaagag gagcccggcg tgcccgggcg
     7981 cgtacgcgac gtacagggac tcggccccga cgacgagccc gttgggcacc cacagcgcca
     8041 ggaacacgta ccggcgcggc gtggacgacc agagcagcgc gttcgtccgc cgggtctcgc
     8101 ggaccgacgg gcggccggtg gcccggggcg gccgggcggt cagcccgaac cgggtcacgg
     8161 ccgccgcgac gacgtacagc cccgccccga tcagcagcgt gccgcgcgtc gagaacaccg
     8221 tcaccagcag cccgcccacc gcgaacccgc agatctgcat cgcgccgccg gtcatgttca
     8281 gcacggagcg gcccagcagg aatcccccgg gcggaacgat ctcgttgagc agcccgtacc
     8341 gtacgccccc gcccggcgac gaggccgcgc ccaccaccag caggacggcg aacgcggccc
     8401 acagcggcag cccgggaacg gcctggacgc aggcggcccc cgcggagagc agcgccaggg
     8461 cggccagcgc ggcgcgcggc ggcagccggt ccgccgccga cagcagggtg agcgccccgg
     8521 ccacctgggc cagcgacggg ccgaacatcg ccagggccga cagcaggggc gagcccgtcc
     8581 gcgtgtacac gagggtgccc agtgccaggc cggtcgcggt ctgggcggcc gtctggacgg
     8641 agacggcggc gaagaagggg gtgaactccg gggtccggaa cagttcgcgg taggtgcgca
     8701 tgggtggagt ctccggacgc cgtcgccggg aacgttactg tttcgcacgg acgcgaaagc
     8761 cccggggcag gcagggacag gcacggtcgg agaacgggag gggtgggggt gcgtgggctg
     8821 gtggcaggtc ggtgcggaca cgctcgcgaa cagccggttc gtcgtctcgc cgctcgcgga
     8881 ggccgtggcg agcctgctgg tcctggagcg ggtcaccgcc gcgcacccgg gtgagcgcgc
     8941 ctggctggag acccacctgc ccgcgtaccg gcggtggaag gccgacgacc cggtctccgc
     9001 gctggtgatc ggcgccgccc tcgcgccccg gtggatcgcc gacttcatcg tccccgtgcc
     9061 ggaccccgcc ccgcccggcc aggccccgcc ctccttcgcc gacgagctga cgcctgtccg
     9121 ggccaccccg cccgaccggg cccgcgccga cctggccgag gcggtgcgcg gtccgttgcc
     9181 cgccgcgctg gaccgggacg acctggcccg gcgtgccgcc gacgccctgg agtgggtctg
     9241 gacgcacacc gtgctgcccg actggccgag gcggcggcgg atcctggagg ccgatgtcat
     9301 ggcccggtcc gcccagttgg ggcgcggtgg ctgggtcgac gcgctgaacg gcatgcgccc
     9361 cggcatccgt tggctgggcg acagccggct ccagatcaac acccacgaca acccgccccg
     9421 cgaactggac ggcgtccagc tgctgttcgt ccccgtgacc ccgtaccagt cctgggtctg
     9481 ctgggacatc ccgcgccggt acgggctggt gtacccgtgc tccggcgcgc tcgccgaggc
     9541 cgggcgcatt cccgtgcccg ccgccctggg ggcgctgatc ggcccggcac gggcggccgt
     9601 cctgctgctg ctcgcctccc cgctgagcac gacgcagctc gtcgcgctga ccggccaggg
     9661 gctgggctcg gtgggccgtc atctgcggat cctcctggag gccggcctgg tccgccgccg
     9721 gcgcgcgggc cgctccgtgc tctatttccg tacggaggcg ggggacgtcc tggtgcacgg
     9781 cgcgggctga gacaggcgtg agagcgcccc gcgcgcgccc ccgcacgccc ccggcccgca
     9841 cccgtccagg gctgggcggc aagcggatac ccatcagtac gcggtgcgct ccgcatggtt
     9901 ggcgcgcatg tacgagtcgt gacaacagtg actatgggca ccgctcgtcg ttgtgacaat
     9961 ttctctctcg ccacgaaaga accgagcgag gggaccgtgc gtgaatccgg agtacgccgc
    10021 gtactgccag gcggaccgcc gcttctacga cgcaccccac cgttcccccg gaccgggcgg
    10081 agccgccgac gaggagcgct cgttctatgc gccgctccgt ggcgccgtac ccgacggctg
    10141 gacccgctcc cggcgcggcg actggctcgc gtacagcccc gacgggctgc gactgccgcc
    10201 ccagggctgg aagatccacg tctcggccgc cctcgacaac gcggcctccg tgctggagcg
    10261 ggtcgtcgcc cactgcctgg aacaccggct ggccttcaag tgcgtgccga acgccgggct
    10321 gttggccctg cgcaacgcca agtacgcgga ccgggcgggc agcgggaagt tcatcaccgt
    10381 ctacccgccg tccgacgagg cgttccccga ggtgtgcacc gccctgaccc acctgctgga
    10441 gggcgagcac ggcccgtaca tcctgagcga ccttcggtgc gggaacgggc ccgtgcacac
    10501 ccggtacggg gcgttcgccg cccgcttctg ctccggcccg gacgggcggc ccgtgcccgc
    10561 cgtcgccgat ccgcagggcc ggctcgtccc ggacgaccgg ggcccgtcct tccgcgtccc
    10621 ctcctgggtg accccgcccg gcttcctgat gccgcacctc gaagcccgtg ccgccgtggg
    10681 cctggccgac ctcccgtaca ccgtggagaa ggcgctgcac ttctccaacg gcggcggggt
    10741 ctacctcggc cgcgacaccc gcaccggcga gcaggtcgtc ctcaaggagg cgcggccgta
    10801 cgccggtctg gccgccgacg gggcggacgc cgtggcccgg ctggagcgcg aacgggccgc
    10861 cctggagcaa ctggacggac tggactgcgt accggccgtc cgggacgtgc tcgaggtcgg
    10921 cgaccaccac ttcctggtcc tccagtacat ccccggcacc accctcaaca ccgtcttcgc
    10981 ccgccgcttc ccgctcgccc ggcagcaccc gtcacccgaa ctgctcgccg aacacgcggc
    11041 ctgggcggcg gagttgtacg ggcaggtcga gcgcgccgtc gaggcggtgc acgaccgggg
    11101 catcgtcatc agcgacctgc acatgagcaa tgtgatggtc gacgaggaga acgggcgcat
    11161 cgtcctgctc gacttcgagg cggcctcccc ggccgccgaa cgccgccgcc agatcgtcgc
    11221 caacccggcc ttcgtcgccc cgcccgaccg gcgcggcgcc gacatcgacc gctacgcgct
    11281 cgcctgcctg cggctcgccc tgtacctgcc gctcaccacg ctgttcggca tcgaccgcac
    11341 caaggccgcc ggcctcgccc gggacatcgc ccgcgtcttc ccggtcaccg aggagacgct
    11401 gcggcccgcg gtcgcggaga tcctgcgcga cacgggtgag cccgcccgcc gggtcgctcc
    11461 cgcctccctt cgagctccct ctcccgctcc cgtgcccgac cccggggact ggccgcgcag
    11521 ccgtgacgcg ctggtccggg ccatcaccgc ctcctgcaca ccggagcgcg aggaccgctg
    11581 cttccccggg gacatcgccc agttcgccac ggccaccggc ggccagtcct tcgcgtacgg
    11641 ggcggccgga gtgctctacg ccctccacga gacgggcgcc ccgccgtgcg aggaggccga
    11701 ggactggctc ctgcggcacg ccaaggaccc ggcgtccggc agccccctcg gcttctacga
    11761 cgggctcacc ggcatcgcct ggaccctgca ccggatcggc cgcaccgccg aggccgccga
    11821 cctcctccgg atcatcctcg accagcccct gcagggcctc gcgcccggcc tccacaacgg
    11881 gtacgcgggc atcggcctcg ctctcgacga cctggcccgc accgcctccg ccaccgacgc
    11941 cccggcgctg tccgcagcgg ccgcccgctg taccgccctc gccgtccgcg cgctcgtcga
    12001 cggcccgccg tcgccccgca ccggactgct gcacggcgcg agcggcatcg ccctgctgct
    12061 ggtgcgccgg tacgcgacca ccggcgacgc cgccctgctc gacctggcgg ccaccgccct
    12121 gcgccgcgac ctggaacgct gcagggccgg ggacgacggc gaactcctcg tcgtcgaggg
    12181 caagcggctg atgccgtacc tcggttcggg cagcgccggc atcgcggccg tcatcgacgc
    12241 ctatctggcc caccgcccgg accccgcgct cgaagctgcg ggccgtgccc tcctgccggc
    12301 cgcgctctcc gccttctacg tccagcccgg actgctccgg ggctcggccg gactcctcat
    12361 gcacctcgcc gccactccgc tgtgcgacga ggccggccgg cagcgcgccg tcgcccgcca
    12421 caccgacctg ctgggcagcc acgccctggc gtacggagac ggactcgcct tcccgggcga
    12481 gcagttgatg cgcctgtcga tggacctggc caccgggacc gccggcgctc tcctcgccct
    12541 gggcgccgcg ctcggcggct ccaccggact tcccttcctg cccgccgctc cggcggcgcc
    12601 tcccggccgc gcgagcggcc ccacggaccg gccccgccag gggtcgtagc aacacaccgt
    12661 tcagcaccac caacgtcccc gaaaggacat catcatggcg cttctcgacc ttcaggcgat
    12721 ggacaccccg gccgaggact ccttcggcga gctcgccacg ggcagccagg tctcgctgct
    12781 ggtctgtgag tacagctccc tcagcgtggt cctctgcacc ccgtgacccg caccggccgg
    12841 cccatcggtg nnnnnnnnnn ccggccacgt gcccccaggg gcagaaaggc caccccgtgc
    12901 ggctgcaccc acgcccgggc acggaatccg gcacccggcg gctcgcccgg cagtacccgg
    12961 cggccctcct cgggctcctc ctctgctcca ccggcggggc gctcgccgcc ctcgccctgc
    13021 ccgccgccct cggccacacc gtcgaccggc tcgtcgccgg cggccccgtg ccctggtccc
    13081 tgctgctgct ctgcgccgcc ctgaccctcg ccgagaccgg gttcgacgcg gcggccgccg
    13141 tgaccggcac gagcaccacc gcccggctca ccgcgtccct gcgcacccgc accgccgccc
    13201 gggtcctggc cgccgaaccc cgccgcgccc ttgccctgcc caccggcgac ctcaccgccc
    13261 ggctcaccgc ccgcaccgcc gacgccgcgt ccgcgcccgt caccgccgcc ggagccgtct
    13321 ccggcgtcct gctcccgctc ggcgcgctcg tcggcctcct cctcatcgac gtctggacgg
    13381 ccgccgccct cctcctcggc gcccccctcc tcgtcgcact gctgcgcgcc ttcacccgcc
    13441 ggaccgccga cgccggggcc gactaccagc gtgcccagtc gctcatcgcc caccggctca
    13501 ccgaggccct cgacggcgcc gacaccatcc gcgccgcccg caccggcgca cacgagcacc
    13561 gccgtgtcct ggaacccctg accgccctcg ccgaacacgg caggcgcacc tgggccgtgt
    13621 acgggcgggc cgtcggccgc agcggcctcc tgctgcccct gctcatgctg ctcgtcctcg
    13681 cggtcgccgg actacggctc cacgcgggcg cgatcggcgt cggcgacctg gtcgccgcct
    13741 cccgctacgc gagcctcgcc gtcggcatcg gcgccctgac cggcgcgctc ggcgccctcg
    13801 cccgcagccg cgccgccgcc cggagcctgg agcccctcct gaacctcgca ccgttcccgc
    13861 accgcggtct gggcccggtg cccgacgccc ccggacacct cgaactccgg gacgtcggcg
    13921 tcgaacagga cggcggcccg ctgctgaccg gcgtccacct gaccgtcccc ggcggcacct
    13981 ccctggccgt cgtcgggcgc tccggctccg gcaagtcggt gctcgccgcg gtcgccgggc
    14041 gactgctcga cccggacacc ggcagcgtgc tgctggacgg cgtcccgatg gacggcatgg
    14101 aaccggcccg gctgcgccgc gaggtggcgt acgccttcgc ccgcccggcc ctccccggca
    14161 ccaccgtcga ggacacgatc gcctacgggc cctggaccgc gtcgcccgaa gccgtacgcg
    14221 acgccgcccg cgccgcccgc gccgacgggt tcctcgcgct gctcccgtac ggctacgcga
    14281 ctccggtcgc cgacgccccg ctctccggcg gcgaacgcca acgcctcggc ctggcacgcg
    14341 cgttcgccca ccccggccgc ctgatgatcc tcgacgacgc gctgtccagc ctcgacaccg
    14401 tgaccgagca ccacgtccga cgcgccctcg acgagcgggc cggacactgc acccgggtca
    14461 tcgtcgccca ccggctgtcc tcggccgcgc gggcggaccg ggtcgcctgg ctggaggacg
    14521 gccggatccg cgcgacgggc cgccacgacg aactctggtc ggacccggac taccgggcgg
    14581 tcttccgcac ggacgtaccc gccgagggct ccgtgcccgc gagccgtacg cccgtcacgc
    14641 cggccgccgg agcggagacc cggtgaaggc cgacggggca cgcccccggc gcgaggagca
    14701 gcacgaggct ccccccgggc gcgacgggca ggacagggcg cactcccagc gcgacgccca
    14761 gcttgaggcg ccctcccggc gcgacgccca gcggcgcggc gcactcccca ggcgcgaagc
    14821 gcggcacggg gcagaccccc ggcgcgatgc ccagcttgag gctcaccctc ggcgcgacac
    14881 ctcgctgcgc cgggtcggcc gcgaggcccg gcccttcctg cgggcccgga ccggcgtggt
    14941 cctgcggctg gccggctggt ccctgctgga gttcgcccag accttcctcg gcgggttcgg
    15001 ggtagcccgc gcgctcgacg acggcttcct cgccggacgt ccgccgaccg gtctcctctg
    15061 gctggccgtc gccgcggtcg ccgtgctgcc ctccgtgccc gccgcccgcg gagtgttcgg
    15121 ccggctcgcg gacctcgtgg agccgctgcg cgacggactg gtccggcgcg ccgtgtcccg
    15181 ggcgctgtcc ggcgcgctcg accgctccgg cgacgtcagc acccggtccc tgtcacaggt
    15241 cactcatcag agtgagatcg cccgggacgg ctgggccgga ctcgtcctga cgctgcgctc
    15301 gttcgtgttc acggcggccg gggccgtcac cggcctgctg gccctgtcgc ccgccctcct
    15361 cctgatcgtg ctgcccccac tggtcctggg gtccgccctg ttcctcggca cgctgccgcc
    15421 gatggccgcc cgccagcgcg actacctcgc cgccgacgag gcgtacgccg cccacgcggg
    15481 ctggctcgcc gcctccgtac gcgacatcgc cgccgcggga gccgccgagc ggacggtggc
    15541 cgagtcccgg gcgctcgccg aggcgcagct cgccgcctcc cgctcactgg cccgctggtc
    15601 gggcgtacgg gtgctggccc tcgccgtctg cggccggttc cccccactcc tgctgctcct
    15661 gggagcgccc tggctgctgc ggaacgggct cacgccgggc gcgctggtcg gcgcgctgac
    15721 ctacctcacc caggcgctcg cccccgccgt ccaggcgctg atgaccatgc tgggcaccgt
    15781 cgggggccgg ctcgtcgtgg tcctggaccg gttcaccgac gcgccgcccc cgcccgccga
    15841 ggacccgccg ccctcccggg acgccgcccc gccgccgcgc ggaaccccgg tcgccgagct
    15901 ccacgaggtc agcttcgcgt acgggccggg cgcccacccc gtcctggacg ggctctccct
    15961 gacgatcggg gcgggggagc acctcgcggt cgtcggcccg agcggcagcg gcaagtcgac
    16021 cctggccgcc gtcctcgccg ggaccgagcg gcccaccggg ggagcggtgc ggtggcgggg
    16081 gcgcccggtg cgcccggccg acgccacctc cgtacgcgtc ctgctgcccc agcacgccta
    16141 cgtgttcagc ggctcgctgc gggacaacct ccgctatcac caccccgacg cccgcgaccg
    16201 ggagatcgcg gccatggcgg acgcgctcgg cctggaagcg ctgctctccc gcctcggttc
    16261 cctcgacgcg gccgtcgaac cggaccggct ctcccagggc gaacggcagc tggtcgccct
    16321 gggccgggcc tatctcgccg ccccgccgct gctgatcctc gacgaggcga ccagccggct
    16381 cgacccggcc gccgagaccc gcgccgagct ggcgttcggg gccctgccgg gtgcgctggt
    16441 cgtcgtcgcg caccggctca gctcggcccg ccgcgccggg cggatcctgg tgatggacgg
    16501 cccgcgcacc cagtgcggca cccccgacga actcctgcgc tcctgcgccc tctaccggga
    16561 cctggccggc ctctgggagc cggaggacgc cggggagccg ggcgaaacga gggagtcgga
    16621 ggagccgggc gagcaggacg aagcggggga gccggaggag ccgggcgggg ccgtcggcat
    16681 cgggcggggg aaagggcgcg ccatcagatc caccccgcct ccttcgcccg tctgatcgcg
    16741 tccagccgat tgcgcgcccc ggacttccgt atggcggcgg ccagataatt gcggaccgta
    16801 cccggcgtca ggtgcagccg accggcaatc ccggccacgg tgtcaccccc ttcggccatc
    16861 gagagcacac tcaattcccg cggggataac ggcatgtcgg ccacctggag gaggctgaag
    16921 gccagcgact cgtcgatatg ccgccccccg tccgccagct tgtgcatcac ctcggaaagg
    16981 tcgtccaccg ggcggtactt gtcgatgtag ccgagcgccc ccgcctcgaa cgcccgccgc
    17041 aggccgctcg gccgatcgct gcgggtgagc acggcgagcg gacacggtcc gccgtgcggc
    17101 gcggtcatcg tcttcacctc gtcgaggacg tccagcgcgc ccggacattc gaggtcggtg
    17161 aggagcacat cgggacacgg cccgctcaac gcggcacgta tcgcaccgtg ttcggcggtg
    17221 cggacctcta tcccccgccc cgtgccgagg agcgacgcca gcgatgcgcg ccacaacggc
    17281 acggtgtgga ccagcagcac ggttgtcatc agtctgccct cagcttttct cttccggccc
    17341 gcccaacgcg gaatgcgacg ggctgtacgc atccggtgac gggtatccag ttgagcgcat
    17401 gggcattcgc gtacgtcgac aaacgggccg aataccgcgc ccgttgggcg cggaaggggg
    17461 cgttcggatg taaatcggga gcgcacatcg cccacggacc catccgtctc gccaccgcag
    17521 gggcgtccgg agggccgggg cggggctgga gtccgcgcat tccccgccgg actgccggat
    17581 cagttcagca gggcgcgcgc ggcgtgggcc ttgcgccgga tgttctcggc cgtagtcggc
    17641 tcgattccgt cgaggatctc cgcatattcc tccatctccg ccgccccgcg caggaattca
    17701 ccgcgctgga cgaggagctg ggcgcgctcg aagcggagcc tggccggatg cgagggcagg
    17761 agcagcgaca gctccaccgc ccacagggcc acgtccgtgc gctcgggccg ggcagccgcc
    17821 cacgcccgga cgttgttcag gatccgcagc acgatctcca gcggccgcgc gggcgtcatc
    17881 atcgacggct caagggccgc cccggtcgcc cccgtgacca gcagctccgc gtcctgaccg
    17941 gtcagcggcg cgcccccggc gaacggatcg gccagcaccg ggtgctcccg atcgccgaaa
    18001 ccgaccacga agtggccggg cagcgccacc ccgtacaccg gtgcgcccgc cctcctggcg
    18061 acctcgatcc agacgaccga caacaggatc ggcaggcccc ggcggcgccg cagcacctgc
    18121 tggaggagtg aggagtccaa ccgctggtag tcgacggagg atccaccgaa cccgcagcgc
    18181 ccgcccagca gttcggccag cgccgaggcc caggcggcgg gggagcggga gccgtacggc
    18241 agcagtcccg ccagccggtc cagctcgatc tgcgcggcgt cgatgccgta cgcgtcgggg
    18301 acggcctccc ccggagtcac cgggcggact tcggccgggc ccaccggtcc ggcctccgcg
    18361 cccagcagca gacacaggag ggcgaggtcc ggccgctcgg accgggcctc ctcggcgaac
    18421 tgccgccgcc gctcggccgt tccggaatcc agcgcgctca tatgcgaccc atgtccctgt
    18481 ccctgctcct gtgcgtcgat ccaccggagg gcccggagcg ggggcctccg gtgcccgtca
    18541 cgccgagcgg tagtggtggt agcggtggtg ggccgcgaag cccatgccgt cgtacagcgc
    18601 ccgcgccccc tcattgtcct cctcgacctg gagccaggcc gccgaggcgc cctcgtccag
    18661 cgcccggcgc gccagcgcgg ccatcaccgt ggtggcgagg ccgcgcctcc gctgctccgg
    18721 agcgacctcg acggccatga accccgccca ccgcccgtcc acgacacacc gcccgatcgc
    18781 ggccggcggg gcgtccggat ccgcgtccgc gcccccggtg tccaccggca ccgtggcgaa
    18841 ccagaccgaa gggccgctgc ccagcacccg cagcacatgg gggccggggg tggagaagcg
    18901 ctggtagcgg gcgagccagg ccgcgtccgg ttcgcgggtc aggcggaccg cccgcacatc
    18961 cgcctccagg tcaccgaccg gcgccagcgc ggcgatccgc acctccgccg agacctcgcg
    19021 ccgccagccg tgccgctcca actccgcgca cagcagctcc tgcgcgccct cggccccggt
    19081 cgccgtctgg acgtacgcgg gcaggccccg ctcctcgtac cagtcccgga cccgtccgag
    19141 cgcctcgccg accggcagcc ccggatcgcc gagcggcagc gcggagttgg cgcgccgcgt
    19201 gaagcccccg gcggcgcgca gccgccagtc gcccagcgct tcgctctcca cgggctgcca
    19261 ggcgcgcgcg gtgacggagg ccagttcccc gaaggaggcg gcggggccac gacggcgggc
    19321 cggagcggcg gggacgacct tgcccgcgac cacggaggat tccacgatgt ggacggattc
    19381 cccgctcttt cgtgtgatcg agagcacacc gttgtcccat gatgtgagca ccccgaccac
    19441 atcggtgaac tccgcgcccg tgcccccacc gtccgtccgg cgtcgaacgg acacgcgttt
    19501 gcccacgtca gcgggtgtga tgcggacttc cagccgtccg ccgatggtga attccacagc
    19561 tctgtccgcc cctcctgttc ggatcgtgcc cgagaacgga gatactagag gcgggcatcg
    19621 acgacgccgc gctcccgcgc gagagccaac gccctaccga ggaggaacga cagcgtgacc
    19681 tacgtcatcg cgcagccttg tgtcgacgtg aaggacaagg cctgcatcga agagtgcccc
    19741 gtcgactgca tctacgaggg ccagcggtcc ttgtacatcc acccggacga atgcgtcgac
    19801 tgcggagcct gtgagccggt ctgcccggtc gaggcgatct tctacgagga cgacactccg
    19861 gaggagtgga aggactacta caaggcgaac gtcgagttct tcgacgacct cggctcgccg
    19921 ggcggtgctt ccaagctcgg tctcatcgag cgcgaccacg cgttcatcgc cggactgccg
    19981 ccgcagaacc agtaagcggc ggcaccacgc gcgcggcccg gtcccgtacg gcttgtcacc
    20041 gtgcggggcc gaggcgtttc cccgtgcggc cgggctccgt caccggatcc cggtcccgca
    20101 gggatccgtc accgcgcgtc cgatccgccg cccgaacgag aacacccgag aaagcagagc
    20161 gccgtgtccg cagtctcctc ccgcctcccg gtcttcccct gggacaagct cgcgccctac
    20221 aagtcgacgg cccaggccca cccggacggc atcgtggacc tgtccgtcgg caccccggtc
    20281 gacccggtcc ccgagctcat ccagcgggcg ctcgtcgccg ccgcggacag ccccggctac
    20341 ccgacggtgt ggggtaccga agccctgcgg gacgcgctca ccggctgggt ggagcggcgc
    20401 ctcggcgcgg tcggcgtgac ccacgccaac gtgctgccgg tcgtcggctc caaggagctg
    20461 gtggcctggc tgccgacgca gctcgggctc ggcgcgggcg acaaggtggc ctacccccgg
    20521 ctcgcctacc cgacgtacga ggtcggcgcc cggctctgcg gcgcggagcc cgtcgtctac
    20581 gacgacccga ccgagctgga cccgacgggt ctgaagctgc tctggctcaa ctcgccctcc
    20641 aatccgaccg gcaaggtgct gtccaaggac gagctgaccc ggatcgtcgc ctgggcgcgc
    20701 gagcacggcg tgctggtctt cagcgacgag tgctacctgg agctgggctg ggacgccgag
    20761 ccggtatcgg tgctccaccc cgacgtctgc ggcggtcact acgacggcat cgtcgccgtc
    20821 cactcgctct ccaagcgctc caacctggcc ggataccggg ccgcgttcat cgcgggtgac
    20881 gcggccgtcc tgggcgagct gctgctcatc cgcaagcacg gcgggatgat gacgcccgcc
    20941 cccgtccagg ccgccgccgt cgccgcgctc ggcgacgacg tgcacgtgtc cgagcagcgc
    21001 gcccgctacg cggaccggcg cctcgccctg cgcgcggcgc tggaggcgca cggcttccgg
    21061 atcgagcaca gcgaggcgag cctctacctg tgggcgaccc gcgacgagcc gtgctgggag
    21121 accgtggcgt acctcgcgca gctgggcatc ctggtggcgc ccggcgactt ctacggcccg
    21181 gcgggcgcac gtttcgtccg ggtggcgttc accgcgaccg acgagcgggt ggccgcggcg
    21241 gtcaagcgcc tgtcctgaac agggccgccg ccacgacggc gacatgacgc gccgagggcc
    21301 tcgggagtgc gcactcccga ggccctcggc gcgttggtcg gtaccgcggt ggatcagccg
    21361 ccgatcggca gaccgcccag cgggaggccg cccttggtca gggagtcggt gggcaggccg
    21421 ccgccgagcg cgtccgtggg gagaccgccg ccgagcgcgt cggtcggcag gccgccgccg
    21481 gctgcctcgg ccacgccgcc cacggcctgg cccgcgttgc ccgcggcctg gccgcatggt
    21541 ctcctgggcg gccgggacgg ccaccccggc ggacttgccg acggtcttgc ccgcggccgg
    21601 gagcgccgtg ccgacgagcc ggccgccggt gtcgcttacc gcctgggtgc cctgctggac
    21661 ggcgctgtcc acggtgttgc cgagaccggc gccgtccagc gcggtcagcc cgccgaggtc
    21721 cggggtcgcc gggagatctg cggcgcttgc ggcgccggcc gcaccgacca cgggggctgc
    21781 gcctgcggcg atcagcagcg cggcacgagc gatccgacgg gtcaggggga gggacatgat
    21841 gctccttcag cgggttgtgc acgaatctgt ctgtccggtg atcggacgca ctgacaaccg
    21901 cttcggggga gggggaggtt gcggtgggca aaggtaaaga ctgagtaatg cgtccgatta
    21961 tccgcagcgg aagaacccgg gcaaacattc cataccgccg tggtccgatg aaccgtcact
    22021 tcccttgggc ggcaagggaa tcggagcagg tccgcgaagg tgcgaggagt cgcgcggaaa
    22081 acatccgggg acatggcccc caaggtccgt acgggtgacg gggcgtacta ctgaacgacc
    22141 tggatcctga ccgccgtcgt gcccgtttcc ttatccttcg cacgttccgt ccgccagccg
    22201 gtaccggcgt cccagacccg gtccgcgtag ctcacgcgct cgatccgcag ggcctcggac
    22261 tgtgccacgg cccagtgcgc cagctcccag ccgcgctgcg cggccttgtc ctccgactgc
    22321 gccgcggccg ccggaacggg caccgagacg gtcgacgcgg cggacgcgcc cgcggccacc
    22381 gcgtcgggca ggacgccctt gccgaaggcc cgcaccagct cggcccgcac ctgggcggag
    22441 tcgcccggac cgtccgccgt ggccgtcgac ggggtgcagt tcagtgcggc cggcctgcgc
    22501 ccggtcagcg cggcggccag cagcgcggcg tccggctcgt gcttcgcgta cgcctgcggg
    22561 aacccgctcc gctgcacacg ctgcgctgca acggtcagcg gcagccgcga gtagcccgga
    22621 acctcggcga gatggtcgta gaactcacc
//
