LOCUS       NZ_CP096281            31373 bp    DNA     linear   CON 08-JUN-2024
DEFINITION  Streptomyces sp. WAC00303 chromosome.
ACCESSION   NZ_CP096281
VERSION     NZ_CP096281.1
KEYWORDS    RefSeq.
SOURCE      Streptomyces sp. WAC00303
  ORGANISM  Streptomyces sp. WAC00303
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1  (bases 1 to 8548838)
  AUTHORS   Meyer,K.J., Tan,S. and Nodwell,J.R.
  TITLE     Genome Sequence of WAC00303 Direct Submission
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 8548838)
  AUTHORS   Meyer,K.J., Tan,S. and Nodwell,J.R.
  TITLE     Direct Submission
  JOURNAL   Submitted (19-APR-2022) Biochemistry, University of Toronto, 1 Kings
            College Circle 5207, Toronto, ON M5S 1A8, Canada
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: 15-MAR-2022
            Assembly Method                   :: Flye v. 2.8.1
            Assembly Name                     :: WAC00303
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 58.0x
            Sequencing Technology :: Oxford Nanopore; Illumina NextSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_023210535.1-RS_2024_06_08
            Annotation Date                   :: 06/08/2024 05:21:48
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 7,823
            CDSs (total)                      :: 7,731
            Genes (coding)                    :: 7,293
            CDSs (with protein)               :: 7,293
            Genes (RNA)                       :: 92
            rRNAs                             :: 6, 6, 6 (5S, 16S, 23S)
            complete rRNAs                    :: 6, 6, 6 (5S, 16S, 23S)
            tRNAs                             :: 71
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 438
            CDSs (without protein)            :: 438
            Pseudo Genes (ambiguous residues) :: 0 of 438
            Pseudo Genes (frameshifted)       :: 228 of 438
            Pseudo Genes (incomplete)         :: 241 of 438
            Pseudo Genes (internal stop)      :: 26 of 438
            Pseudo Genes (multiple problems)  :: 54 of 438
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 18:23:54
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 2543034
            Orig. end                         :: 2574407
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP096281.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            Bacteria and source DNA available from Justin Nodwell, University
            of Toronto.
FEATURES             Location/Qualifiers
     region          1..31373
                     /candidate_cluster_numbers="1"
                     /candidate_cluster_numbers="2"
                     /candidate_cluster_numbers="3"
                     /contig_edge="False"
                     /product="lanthipeptide-class-ii"
                     /product="lanthipeptide-class-iii"
                     /region_number="9"
                     /rules="cds(LANC_like and DUF4135)"
                     /rules="(micKC and not PKS_KS)"
                     /tool="antismash"
     cand_cluster    1..31373
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="cds(LANC_like and DUF4135)"
                     /detection_rules="(micKC and not PKS_KS)"
                     /kind="neighbouring"
                     /product="lanthipeptide-class-ii"
                     /product="lanthipeptide-class-iii"
                     /protoclusters="1"
                     /protoclusters="2"
                     /tool="antismash"
     cand_cluster    1..23321
                     /candidate_cluster_number="2"
                     /contig_edge="False"
                     /detection_rules="cds(LANC_like and DUF4135)"
                     /kind="single"
                     /product="lanthipeptide-class-ii"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..23321
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:13321](+)"
                     /cutoff="20000"
                     /detection_rule="cds(LANC_like and DUF4135)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-ii"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..13321
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="cds(LANC_like and DUF4135)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-ii"
                     /protocluster_number="1"
     gene            complement(900..1547)
                     /locus_tag="MWG59_RS11805"
                     /old_locus_tag="MWG59_11805"
     CDS             complement(900..1547)
                     /GO_function="GO:0042834 - peptidoglycan binding [Evidence
                     IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006124625.1"
                     /locus_tag="MWG59_RS11805"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MWG59_11805"
                     /product="peptidoglycan recognition family protein"
                     /protein_id="WP_097934455.1"
                     /transl_table=11
                     /translation="MNLPQPSRRHVLLAGAGGLAAAALPGTAHALDVVEPDIDSTSQWK
                     ARPPQGPIDLVGKRPTMIVVHHTVSANTSDVSRAQAHSHAHWVQDLHMDKNGWTDTGYH
                     FLVSRGGWITEGRHQSLSTLRGGRDFVMGAHTSGQNGAGIGIANEGAYHDGAQPPRAQW
                     EVLVALCAYTCHQYGIAPSRIYGHKDFGDTLCPGVLHDKLPQLRSEVAASTG"
     misc_feature    complement(1476..1478)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     CDS             1564..1701
                     /gene="allorf_2544598_2544735"
                     /locus_tag="allorf_2544598_2544735"
                     /protein_id="allorf_2544598_2544735"
                     /tool="antismash"
                     /transl_table=1
                     /translation="MVVPGLPDSDSDNGGDSDNGGGCGRWRRYGRAGAVLTRPPRVRGR
                     "
     CDS_motif       1564..1626
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence: MVVPGLPDSDSDNGGDSDNGG"
                     /locus_tag="allorf_2544598_2544735_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       1627..1701
                     /prepeptide="core"
                     /locus_tag="allorf_2544598_2544735_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class II"
                     /score="-6.40"
                     /molecular_weight="2736.2"
                     /monoisotopic_mass="2734.5"
                     /core_sequence="GCGRWRRYGRAGAVLTRPPRVRGR"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MVVPGLPDSDSDNGGDSDNGG"
                     /leader_location="[1563:1626](+)"
     misc_feature    complement(1607..1619)
                     /note="TFBS match to MatP, Cell cycle regulator,
                     confidence: weak, score: 18.96"
                     /tool="antismash"
     gene            complement(1698..2579)
                     /locus_tag="MWG59_RS11810"
                     /old_locus_tag="MWG59_11810"
     CDS             complement(1698..2579)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003952140.1"
                     /locus_tag="MWG59_RS11810"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MWG59_11810"
                     /product="lysozyme"
                     /protein_id="WP_248584799.1"
                     /transl_table=11
                     /translation="MPAYRSPSRRLRRSRGALLAGALASTAALILTGTGTAVAAPPAPD
                     EPVRSGHAWMGAGTRIEQGPASSAAGGVTPMDTSGVQGIDVSHWQGAINWGSVKAAGID
                     FAYMKATEGTTYKDSRFSANYTGSYNAGLIRGAYHFARPDVSNGATQANYFASGGGGWS
                     KDGKTLPGVLDIEHNPYGAMCYGLSTTQMRTWINDFYNTYKARTTRDVVIYTTASWWNT
                     CTGSWTGMATKSPLWVAHWGTSSPNIPSGFPTWTIWQYSATGRVAGVSGDVDRNKFNGS
                     FARLQALANNTV"
     CDS             complement(2646..2786)
                     /gene="allorf_2545680_2545820"
                     /locus_tag="allorf_2545680_2545820"
                     /protein_id="allorf_2545680_2545820"
                     /tool="antismash"
                     /transl_table=1
                     /translation="MGRDRVPGTFRSENFRRSDTFSQVGCGGTGLDRRASLRLPRSVRY
                     S"
     CDS_motif       complement(2760..2786)
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence: MGRDRVPGT"
                     /locus_tag="allorf_2545680_2545820_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       complement(2646..2759)
                     /prepeptide="core"
                     /locus_tag="allorf_2545680_2545820_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class II"
                     /score="-5.30"
                     /molecular_weight="4091.5"
                     /monoisotopic_mass="4089.1"
                     /core_sequence="FRSENFRRSDTFSQVGCGGTGLDRRASLRLPRSVRYS"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MGRDRVPGT"
                     /leader_location="[2759:2786](-)"
                     /alternative_weights="4109.5"
                     /alternative_weights="4127.5"
                     /alternative_weights="4145.6"
                     /alternative_weights="4163.6"
                     /alternative_weights="4181.6"
                     /alternative_weights="4199.6"
                     /alternative_weights="4217.6"
     misc_feature    complement(2687..2702)
                     /note="TFBS match to DasR, N-acetylglucosamine dependent
                     repressor, confidence: medium, score: 23.02"
                     /tool="antismash"
     CDS             complement(2693..2851)
                     /gene="allorf_2545727_2545885"
                     /locus_tag="allorf_2545727_2545885"
                     /protein_id="allorf_2545727_2545885"
                     /tool="antismash"
                     /transl_table=1
                     /translation="MSTGGKVLSGGRSPLLRTFVRPWAGIGCRGPSGVKIFAVPTRSRR
                     WGAAAQV"
     CDS_motif       complement(2819..2851)
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence: MSTGGKVLSGG"
                     /locus_tag="allorf_2545727_2545885_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       complement(2693..2818)
                     /prepeptide="core"
                     /locus_tag="allorf_2545727_2545885_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class II"
                     /score="-5.40"
                     /molecular_weight="4389.1"
                     /monoisotopic_mass="4386.5"
                     /core_sequence="RSPLLRTFVRPWAGIGCRGPSGVKIFAVPTRSRRWGAAAQV"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MSTGGKVLSGG"
                     /leader_location="[2818:2851](-)"
                     /alternative_weights="4407.1"
                     /alternative_weights="4425.2"
                     /alternative_weights="4443.2"
                     /alternative_weights="4461.2"
     gene            2871..3578
                     /locus_tag="MWG59_RS11815"
                     /old_locus_tag="MWG59_11815"
     CDS             2871..3578
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018511335.1"
                     /locus_tag="MWG59_RS11815"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MWG59_11815"
                     /product="VOC family protein"
                     /protein_id="WP_248584800.1"
                     /transl_table=11
                     /translation="MIETTIPMLPCRTSLIETTVDFYTALGFATTYLQKSPYAYAVVER
                     GAVELQLYGMKEYDPASSHSGCYVLTDDVDGLHAAFRAGLKEAYGRVPARGLPRIGPLK
                     DMSYGVRQFLVTDPTGNTIRIGQPISEDQNHRPAPKETFARALHMADLFADSKQDLPGA
                     AKIIDRVLGLTDEHPTPAQKLRLLVLRGDIAQRMGDAEKAGVLLEEAAAVRLGPEEREA
                     AADTLARLADLRG"
     gene            complement(3629..4183)
                     /locus_tag="MWG59_RS11820"
                     /old_locus_tag="MWG59_11820"
     CDS             complement(3629..4183)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018959320.1"
                     /locus_tag="MWG59_RS11820"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MWG59_11820"
                     /product="DinB family protein"
                     /protein_id="WP_248584801.1"
                     /transl_table=11
                     /translation="MTESTVEAWPEPPLAGTEAAAVLGALERQRATLAWKCSGLDAAGL
                     RATVGASTVTLGGLLKHLAHVEDSHFARLWLGVPVGAPWDAVDWDSDPDWAYRSAAQDT
                     PGQLRTLWQESAARSRATVDAALRAGGGLDRLGAHVTRSGERPNLRRILLDLIEEYARH
                     VGHADLIRESVDGLTGEDPPR"
     gene            complement(4386..5222)
                     /locus_tag="MWG59_RS11825"
                     /old_locus_tag="MWG59_11825"
     CDS             complement(4386..5222)
                     /GO_function="GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018552741.1"
                     /locus_tag="MWG59_RS11825"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MWG59_11825"
                     /product="sugar phosphate isomerase/epimerase family
                     protein"
                     /protein_id="WP_097934459.1"
                     /transl_table=11
                     /translation="MTDGRLSRLSLNQETIKQWSLPELTEGCVKAGIGMVGLWRDPVQA
                     YGVERTARLLADAGLTVTSLCRGGFFTALDPAARARALDDNRAAIDEAAALSTDTLVLV
                     SGGLPPGSRDLYGARERVAEALAELAPYAATRGVRLAIEPLHPMYASDRCVVSTLGQAL
                     DIAERFPADQVGVVVDTYHLWWDDRAPAQIARAGAGGRIHSFQLADWITPLPAGVLLGR
                     GQLGDGSVDFREFRRLVEAAGFDGPIEVEIFNEALWARDGAEALAEVAERYVQHAC"
     gene            complement(5219..6367)
                     /locus_tag="MWG59_RS11830"
                     /old_locus_tag="MWG59_11830"
     CDS             complement(5219..6367)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003969064.1"
                     /locus_tag="MWG59_RS11830"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MWG59_11830"
                     /product="dihydrodipicolinate synthase family protein"
                     /protein_id="WP_097934460.1"
                     /transl_table=11
                     /translation="MTIHLPQGPYTPRATPLDLAPGAAAPTSRTVFSAAHVVADPYADI
                     GPDDPAAVDWESTLAFRRHLWAHGLGVAEAMDTAQRGMGLDWAGAAELIRRSAAEAKAV
                     GGRIACGVGTDQLPGGGTPTLAEVTAAYEEQLALAEENGVQPILMASRALVRAARGPED
                     YLATYAHLLRQASEPVILHWLGPMFDPALEGYWGSADLDDATDTFLKVIAEHPDKVDGI
                     KISLLDAAREIDVRRRLPGGVRCYTGDDFNYPELIAGDERGFSHALLGIFDPLGPLAAH
                     AVRVLDTGDVDGFRALLDPTVELSRHLFRSPTRFYKTGVVFLAWLSGHQDHFTMVGGLQ
                     SARSLPHLAKAYELADRLGLFPDPDLAEHRMRSLLAVHGGTR"
     gene            complement(6408..7559)
                     /locus_tag="MWG59_RS11835"
                     /old_locus_tag="MWG59_11835"
     CDS             complement(6408..7559)
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /GO_function="GO:0016651 - oxidoreductase activity, acting
                     on NAD(P)H [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) GFO_IDH_MocA"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) GFO_IDH_MocA_C3"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1079: oxidoreductase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005317389.1"
                     /locus_tag="MWG59_RS11835"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MWG59_11835"
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="WP_248584802.1"
                     /sec_met_domain="GFO_IDH_MocA (E-value: 2.6e-10, bitscore:
                     39.8, seeds: 39, tool: rule-based-clusters)"
                     /sec_met_domain="GFO_IDH_MocA_C3 (E-value: 4.9e-26,
                     bitscore: 90.0, seeds: 4226, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTRRTVRIAMNGVTGRMGYRQHLVRSILAIREQGGLDLGDGEVLW
                     PEPVLVGRRAHALEELAERHGLTEWSTDLDAVLADDTIDIYFDAQVTSARVEAIKKAIA
                     AGKHVYTEKPTATDVEGALDLARLARDAGIKHGVVQDKIFLPGLLKLKRLIDGGFFGEI
                     LSVRGEFGYWVFEGDWQEAQRPSWNYRAEDGGGIVVDMFPHWEYVLHELFGQVTSVTAH
                     VQTHVPQRWDERGKPYEATADDAAYGIFQLAGGAVAQINSSWTVRVNRDELVEFQVDGT
                     HGSAVAGLRNCRVQHRSSTPKPVWNPDLPVTESFRDQWQEVPDNQQFDNGFKAQWELFL
                     RHVALDEPYGWDLLAGARGVQLAELGLKSSAEGRRFDIPELTL"
     misc_feature    complement(7571..7591)
                     /note="TFBS match to MntR, Manganese transport regulator,
                     confidence: weak, score: 18.75"
                     /tool="antismash"
     misc_feature    7583..7594
                     /note="TFBS match to CcpA, Catabolite control protein A,
                     confidence: weak, score: 15.83"
                     /tool="antismash"
     gene            7669..8769
                     /locus_tag="MWG59_RS11840"
                     /old_locus_tag="MWG59_11840"
     CDS             7669..8769
                     /GO_function="GO:0000976 - transcription cis-regulatory
                     region binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_function="GO:0043565 - sequence-specific DNA binding
                     [Evidence IEA]"
                     /GO_process="GO:0006351 - DNA-templated transcription
                     [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /GO_process="GO:0045892 - negative regulation of
                     DNA-templated transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1078: LacI family
                     transcription regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012380887.1"
                     /locus_tag="MWG59_RS11840"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MWG59_11840"
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="WP_097934462.1"
                     /transl_table=11
                     /translation="MTVTLADVAARARVSPATVSRVLNGNYPVAASTRERVLRAVDDLD
                     YVLNGPASSLAAATSDLVGILVNDIADPFFGIMAGAAQTQIGGPGDGSGRAGGEKLAVI
                     CNTGGSPERELTYLTLLQRQRAAAVVLTGGAVEDPAHRAAMSAKLTKLADAGTRIVFCG
                     RPPLPEGDALVAALAFDNRGGGRRLAEHLISLGHRRIGYVAGPPERTTTRHRLEGHREA
                     LRAAGLDAAPDEADGGRGSDDQDRLTVHGPYDRRSGYEATLELLRRAPDVTAIVAANDT
                     VALGACAAVRDQGMRIPQDISVAGFDDLPFSVDAVPALTTVRLPLFEAGARAGRLAMGK
                     ENPPPGGIATIAAELMIRGSTAAPRG"
     cand_cluster    8695..31373
                     /candidate_cluster_number="3"
                     /contig_edge="False"
                     /detection_rules="(micKC and not PKS_KS)"
                     /kind="single"
                     /product="lanthipeptide-class-iii"
                     /protoclusters="2"
                     /tool="antismash"
     protocluster    8695..31373
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[18694:21373](-)"
                     /cutoff="20000"
                     /detection_rule="(micKC and not PKS_KS)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-iii"
                     /protocluster_number="2"
                     /tool="antismash"
     proto_core      complement(18695..21373)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(micKC and not PKS_KS)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-iii"
                     /protocluster_number="2"
     gene            complement(8825..9169)
                     /locus_tag="MWG59_RS11845"
                     /old_locus_tag="MWG59_11845"
     CDS             complement(8825..9169)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003969060.1"
                     /locus_tag="MWG59_RS11845"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MWG59_11845"
                     /product="hypothetical protein"
                     /protein_id="WP_248584803.1"
                     /transl_table=11
                     /translation="MTEPTHHSTYNGPVFNQTGAQNIGINNGYVGAAQDPELHAAVREL
                     TARLRELTAHLTPDQARTVEETLPVLALDREAMTERGLTLARLGQLTTAVGPVAQPVAD
                     ALGRLLGLLG"
     gene            complement(9166..9756)
                     /locus_tag="MWG59_RS11850"
                     /old_locus_tag="MWG59_11850"
     CDS             complement(9166..9756)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018554547.1"
                     /locus_tag="MWG59_RS11850"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MWG59_11850"
                     /product="DUF6232 family protein"
                     /protein_id="WP_248584804.1"
                     /transl_table=11
                     /translation="MDSTGNFGQPTTPPTGPPSSPPPSSPPPDPPAGPPSQPPPLPPLP
                     RPGGVLEIAVKRRMLWIGSAALPLHNLTRVEAIKIKPDRNVLRFLLGLGLVAFVYSVTD
                     WAPVLVLLIVLVVYFVKALIAPETPVLVVETAGSSRVLVTLPSVDELRTIAGRIVHAID
                     HPEAEFTAYVHQLNNYNGPVFNQNGGQNTGIRL"
     gene            10001..13321
                     /locus_tag="MWG59_RS11855"
                     /old_locus_tag="MWG59_11855"
     CDS             10001..13321
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-ii: DUF4135"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-ii: LANC_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1070: lanthionine synthetase C family protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007450767.1"
                     /locus_tag="MWG59_RS11855"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MWG59_11855"
                     /product="type 2 lanthipeptide synthetase LanM family
                     protein"
                     /protein_id="WP_248584805.1"
                     /sec_met_domain="DUF4135 (E-value: 1.4e-103, bitscore:
                     345.8, seeds: 79, tool: rule-based-clusters)"
                     /sec_met_domain="LANC_like (E-value: 9e-24, bitscore: 82.7,
                     seeds: 47, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAEKDLIDRGTARRPAPAVSVVSAPASSVASGTPGTSGTSGTSGT
                     AAIVAFGGAAGEPWWLPGVVGGSDSGEPGWAVFAREAVASAPRDVVVADRAYPGLSGFG
                     PVVAPFVEAATRRLRDALADDGPAVNGTVGGRATNGPAADGSSAVLADFRRQLTRRLSR
                     IAGRTLVTELHEARRLGRLRGEGSEERFRDFVRRTARRDGLALLVTGYPVLARLLATAC
                     LNAGDAFAEMAARLAADRHLLAPSGVLGDRAGSPESGLGGNAGPGALTGVEAGAGDSHR
                     GGRSVMLLRFADGARLVYKPRPLAAHRHFNTLAEWFGSLPGAPELRVLRVLDRGDYGWA
                     EFVEERPCSSAAETRQFYRRQGALLALLHTLDGTDLHHENLIACGPHPVLVDVETLFHP
                     PLGPARSTDPAARALHDSVHRVGLLPQLLVGDTTALDMSAIGGGRAASSPIETADWAEA
                     GTDRMRLVRRAGRFTESANRPRLGGVAAAPSAYTDALCGGFRAGYTAISDHRAELLGED
                     GLLRLFARDEVRVVPRPTWTYTTLLDESTHPDLMRDATERHQVLSLLRTPLLGVPALPG
                     VEDEEVAELWCGDVPVFGTRPGSTELWSGTGRTVPGAAPDRPSYDTARDRSPHDLAAGD
                     AVGPTGLARVEAKVRAMDTVDRQDQERIIRAAMVSTSPEPPHRAGPGGRSRSAATAPEP
                     EQLLSAARSVGDQLVSLAYRHESRTNWIGLELLGERYWRLTPMAADLAGGYTGPALFLA
                     QLAALTGASRYAEAAREALAPVPGLLDALHGRADELGSLGSGAFAGLGGIAYALTEVGT
                     LLGDRDVLDLAGPAVRLSCAASAAEDGYGVRGGAAGGLVSLLAVHRATGRPEAWRGAER
                     CAERIAAAPLPGSGGFADGAAGIGWALLRFAGAGGDARHRIAGLEALRRATAGAAHVTT
                     AATAGAPDGTTAGTTAGAPHGATAGTTREAGAGAAAGPAWCGGVAGIALAVADSPDALA
                     DPELSGWLAARSGELAGIGPLADDSLCHGESGLLELLGHGSLPAARPAWMRRAGTLLAS
                     ADRAGPQCGTPGRVPHPGLLTGLSGIGHGLLRAGFPDRIGSALLLRSSPAPLTEPRLS"
     gene            13379..13576
                     /locus_tag="MWG59_RS11860"
                     /old_locus_tag="MWG59_11860"
     CDS             13379..13576
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010056547.1"
                     /locus_tag="MWG59_RS11860"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MWG59_11860"
                     /product="hypothetical protein"
                     /protein_id="WP_050360846.1"
                     /transl_table=11
                     /translation="MKQFGESALQASGEIAHEGTPEHPAGQISLGSTGGLGARSRLLSA
                     SEGESGYSHDLPWTTMTAPW"
     misc_feature    complement(13598..13613)
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: weak, score: 18.14"
                     /tool="antismash"
     gene            13656..16577
                     /locus_tag="MWG59_RS11865"
                     /old_locus_tag="MWG59_11865"
     CDS             13656..16577
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1149: LuxR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006124639.1"
                     /locus_tag="MWG59_RS11865"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MWG59_11865"
                     /product="AAA family ATPase"
                     /protein_id="WP_097937111.1"
                     /transl_table=11
                     /translation="MRATSPVIVGRDEEIGLLSSALDAVQRRSGRALFLVGEAGIGKSR
                     LVGECAYRAYGLGMPVLRGRATSTGLVVPFRPLAEALASRFRAAGTPTDPELAPYHPAL
                     ARLVPEWRRGGSPGYPETVVELAEALLRLLSVLGREAGCAILLEDLHDCDTETVAVVEY
                     VIDNLADLPILFLGTLRPEPGAALDLVRSTERRHAATVRELGPLRDDRVRALTGACLEA
                     RPEEIPESVHRRLAERAAGNPYLLEVLLADLLDTGRLRRTDDGWVAAEQPGGSVPSDIV
                     RSWARRLERLDEPVRDLLLASATLGSQFSVTVLQTVTGFEDRALFTHLRSAVEAGVIAP
                     DGAAPDRYTFRHSLTAEALISSLAPAERASLARRAAGAIEHSGQPLDEDGRQLVASLQL
                     AAGNRAGAARQFAEAGRRMLASGAHGSAVVLLERAHPLAAETDRAAVAESLAVARAEGG
                     DLDAALALADALPPVPARSEAAARRGLIHIELAWAAVMAERTADAALQVEAARVLLGPS
                     PPPGRRAALVVVDGYLALLPGHGQKPRDPADSERVVREAAETAEAEGLPVVACQAWQLL
                     ALLRREEGFDAADAALERMLSISTEHALPVWRVEALVRLGANAFMRTGDAARLLSARAA
                     ATELGALLLTRTVDGLLAMNAVMCARWEEAQEIIDRSAEASARVGDRSAHRYLLLAGAT
                     MAAHRGRRREMDRALAAFRRAGGEQSLLVPLRSGLCRAFGALLEEDRERAAAGLDEALA
                     WEADHPSYYYLSGRYGLRPLLRVLAGEADRAELAEARAAPGGALAWNRQFLELADAVLL
                     GREGDPSGAARLMASFDVRSAPFPVARHLGLRLVADAARADGWGEPVAWLRSAEEYFYG
                     AGVQAVASACRAALRQAGASVGQHRGGWDRIPSPLRTSGVTPREYEVFVLLPERPGNQQ
                     IARRLSISPRTVEKHMASLLSKTGRADRAALCEFAAECAVEPA"
     misc_feature    14550..14552
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            16764..18626
                     /locus_tag="MWG59_RS11870"
                     /old_locus_tag="MWG59_11870"
     CDS             16764..18626
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1041:
                     transcriptional regulator, SARP family"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015608633.1"
                     /locus_tag="MWG59_RS11870"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MWG59_11870"
                     /product="AfsR/SARP family transcriptional regulator"
                     /protein_id="WP_097937112.1"
                     /transl_table=11
                     /translation="MTRPPVRTAPPGAVYFSLLGPLTARLDGHELPLGPRKQRLVLATL
                     LSRPNTPVPVEVLTDAVWPDDPPRTARKNLQVYVSAARTLLGPAGHEGRDRVVHGCGGY
                     LLRIAEGELDTLRFGSLARAGRAAAGRGDLAGAARLLREALDLWEGPPLNDLRDSAGVA
                     EEAGRLEARCLTVYEDWAETEIELGRPAVAVDGLRDLVERHPLRERLRAAWMNSLHQSG
                     RQAEALAVYDDYRQLMARELGLEPSPAMTALYRSMLGRGREARRPAPAREAVSPAAPPS
                     CTAAFTGRPGELRDLLEVLGCGEERVVVVSGPAGAGKSALALRAAHLLADRFPDGRVRV
                     RVRREDGTTRSRAEILAELGRLCGVAGNAASPGNTASPEGGAGGDRAATAALADAWQEW
                     QARHRALVVLDDVPDEASVRGLLSRSGKCSVLITARGQLAGLAPVHRIALPALADGEAL
                     ELLGKLIGAGRLRADPGAALRIVRACGGLPLAVEVSGMRLAVLRHLPLAEYADRLDDPS
                     AALDELVAGDVSVRHRIASGWQDLADGDRWVLGRLAGLAEDGGFTLDRATEALGCGERA
                     AIRAVESLIDAGAVTSPAGEVTAHAALYEVPRLLGLYAHEREGV"
     gene            complement(18695..21373)
                     /gene="lanKC"
                     /locus_tag="MWG59_RS11875"
                     /old_locus_tag="MWG59_11875"
     CDS             complement(18695..21373)
                     /GO_function="GO:0004672 - protein kinase activity
                     [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_process="GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /GO_process="GO:0006468 - protein phosphorylation [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="lanKC"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-iii: micKC"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Pkinase"
                     /gene_functions="regulatory (smcogs) SMCOG1030:
                     serine/threonine protein kinase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007450771.1"
                     /locus_tag="MWG59_RS11875"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MWG59_11875"
                     /product="class III lanthionine synthetase LanKC"
                     /protein_id="WP_248584806.1"
                     /sec_met_domain="micKC (E-value: 2.5e-210, bitscore: 699.5,
                     seeds: 18, tool: rule-based-clusters)"
                     /sec_met_domain="Pkinase (E-value: 1.9e-08, bitscore: 32.8,
                     seeds: 54, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPGLHQTQLYCLADRRYYETPARLQDESTRYPLDSDPPGEGWRRI
                     AGGLWTSLLPEDREPAGQGWKIHVSTVPEEAEETLLDTARICRAHGVPFKFLRSERALL
                     LMSGKYMSRAGAGKFITVYPPDETVFLRVLEELTRALAGRRGPYILSDLRIGDAPVYVR
                     YGAFVSRWCLDEDGERVLALRHPSGELVPDERGVVFRVPPWVTVPDALRPHLAARAAAG
                     DAAFPYDVSESLQFSNAGGIYLARHRETGRQVVLREARPHSGLDEAGDDAVTRLHREHR
                     ALTALAGLDCVPEVYGVRTVWEHHFLIEEHIEGATLLEEIVGRFALLHSTGTATELAPY
                     IAWVESVTERLTEALAAVHGRGLRFGDLHPSNIIIRPDGRVALIDFEYATALDDRDTPV
                     AGAPGLQAPAGTVGAEADAYALWATWLYMLMPIMEMAGHDRAKALTLERWARRRYGLDA
                     GAGPRRPSALRAAESTDGHERETAALLDGPEPDWAGLRERLLRGIHAGATPERTDRLFP
                     GDPEVFSTGGSDVAHGAAGVLHALHRTGAPVPRVWTDWLVDTARRRDPAAPGGLYGGLP
                     GTAVVLSALGRREEGRELYERSAAAPPSASADLMNGRAGIALAALRLARPDRAGDGSPD
                     AKIDHDLVDAAARTAHDLDRLVRGESVPGLRAPASAGLLRGLSGAALLHLELHALTGDE
                     QFLAAAGRALEAEAAHCVTMPDGTVQVKDGRRHFLYLDQGSGGFALVAQAFLARRDSPE
                     PVQRRPRFAPSGHTSADAALAALLPGVAKGCAFEFVREPGLFTGRAGLMAVAGALSPDG
                     RRAPGVLASVRNLSWHLVADEDRLFVPGAGLMRCSADLATGAAGLLMSLHFLSGATTGT
                     DGRDGRDGSGETDLLELLTLG"
     gene            complement(21385..22677)
                     /locus_tag="MWG59_RS11880"
                     /old_locus_tag="MWG59_11880"
     CDS             complement(21385..22677)
                     /GO_function="GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1020: major
                     facilitator transporter"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003969052.1"
                     /locus_tag="MWG59_RS11880"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MWG59_11880"
                     /product="MFS transporter"
                     /protein_id="WP_050360848.1"
                     /transl_table=11
                     /translation="MAEPLRSNRDFRLLWLSGLFAALGGQMSAIALPLLILKETGSAVQ
                     AGAVGTVAVCAVLITMLPGGVMADRVERRRLMRLCDVGSLAAVTALALAVWNGHAPMAL
                     VLLVATSGAVLNSVYAPAAFGLMRAVVPPDQMSTATARLQARTSTARLVGPLVGGALFG
                     VHQALPFTAQFLGLFLSTVCVALVRTRSAARTRAGSVFSRRELTAGLSFLWQLPYLRTV
                     LLVFGLGMNFSFGALTFSALAVFSDSGRSGLGGGFVITCVSAGALAGALIAPRFAAERH
                     VRTLIVITCWSCVGTAAVLAWLSSPLVAGLLCALCMCLSTVASIGFLSTLLVVTPEDRI
                     GRVQSAAGFLSSIVQPFGPLAGGFLLATLDSSAAFGVIGCVLAVSAAVVTLAPSVRAGA
                     AAAREKPEPAGTVSTRPATAPAPDAAGPGAP"
     misc_feature    22662..22676
                     /note="TFBS match to VqsM, Regulator of quorum-sensing
                     signalling systems, confidence: strong, score: 19.35"
                     /tool="antismash"
     assembly_gap    22721..22730
                     /estimated_length=10
                     /gap_type="within scaffold"
                     /linkage_evidence="paired-ends"
     gene            complement(22829..22984)
                     /locus_tag="MWG59_RS11885"
                     /old_locus_tag="MWG59_11885"
     CDS             complement(22829..22984)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="MWG59_RS11885"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="MWG59_11885"
                     /product="hypothetical protein"
                     /protein_id="WP_164219961.1"
                     /transl_table=11
                     /translation="MSENTKPAAGDAEETPEVEAHSVLDLQETANNHDIIQPPGNCVST
                     VSLVLG"
     gene            23307..24431
                     /locus_tag="MWG59_RS11890"
                     /old_locus_tag="MWG59_11890"
     CDS             23307..24431
                     /GO_function="GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /GO_function="GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA]"
                     /GO_function="GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007450777.1"
                     /locus_tag="MWG59_RS11890"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MWG59_11890"
                     /product="radical SAM protein"
                     /protein_id="WP_248584807.1"
                     /transl_table=11
                     /translation="MELAELVARRPFPAAGLLLGLTRRCPLRCAHCSTGSDLFTREEPD
                     GGQLERFVASFSEENRPDVVMLTGGEPLLLPALAERLSTLARSAGSRTALLSGMFFARS
                     ASRRGRRGAAIPPAILRAIRSVDHFSASLDVHHEREVPRADVFRALHRIRDEGVAVSFH
                     LTGTGASDPYLADITRAVEKEFGGRVPCLVNEVRPFGRAASWARPARTGPDPAAASPCS
                     MAAWPVVAFDGRVLACCNQDTVDRRPVPAHLDLGHIGVDDWATVRRRALESPVLRMLRT
                     VGPTHLAARYGSGPGTGSYCDGCRALDGDEAAAAGARAVAGGAAGALLDLTAAVRGSRE
                     GAQGVVRRHGCAAYAPLVVTGGPRLPETEAQDLR"
     gene            24428..25183
                     /locus_tag="MWG59_RS11895"
                     /old_locus_tag="MWG59_11895"
     CDS             24428..25183
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007450779.1"
                     /locus_tag="MWG59_RS11895"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MWG59_11895"
                     /product="iron-containing redox enzyme family protein"
                     /protein_id="WP_248584808.1"
                     /transl_table=11
                     /translation="MSATTGAVSLGTTGASARLRVKLLLLEPEFRDATHHMWRAEGLLP
                     RYRTYLCTMHTVIRASVPLMELALDRARVRAASGDPLAAPLAAYLEEHIREEEGHDAWL
                     LEDLRAAGGDPEDALGPLPSPLVASLVGPQYYWIEHHHPVALLGYIAVLEGYAPAPGLT
                     GRIARLTGLPAAALRTVREHSVIDTEHLDELYALLDRLPLGRGPEAAVAVSALHSLDAL
                     TQLFVRLGRSAPAPSLRGAGPVPPMGVTP"
     gene            25180..25398
                     /locus_tag="MWG59_RS11900"
                     /old_locus_tag="MWG59_11900"
     CDS             25180..25398
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018959336.1"
                     /locus_tag="MWG59_RS11900"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MWG59_11900"
                     /product="aroma-sacti cluster domain-containing protein"
                     /protein_id="WP_069756450.1"
                     /transl_table=11
                     /translation="MTGPPENGRRPVLPDALYEAGFPVDLLTEEQREVLSGLTPEELAV
                     LLDVKGRLDAVGPEVQAHGEIAGGALF"
     assembly_gap    25477..25486
                     /estimated_length=10
                     /gap_type="within scaffold"
                     /linkage_evidence="paired-ends"
     gene            25627..28921
                     /locus_tag="MWG59_RS39180"
                     /pseudo=""
     CDS             25627..28921
                     /GO_process="GO:0009190 - cyclic nucleotide biosynthetic
                     process [Evidence IEA]"
                     /GO_process="GO:0035556 - intracellular signal transduction
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1149: LuxR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012380877.1"
                     /locus_tag="MWG59_RS39180"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /product="adenylate/guanylate cyclase domain-containing
                     protein"
                     /pseudo=""
                     /transl_table=11
                     /translation="MNCSSCQQDLPPTARFCSSCGTPCATTGPAGAGPAQAAPAGDERK
                     PVTVLFCDLVGSTALSGVLDPETLRTVTLRYFEAMSAEIVARGGTPEKFIGDAVMAVFG
                     VPVVRDDDARRALAAALGMRRALARLNEELDATLGIELTTRIGVNTGQVVAGSDTTARQ
                     ALVSGETVNIAARLEQNAGPGEILIGPETLLAAGPTVRAEPTGPLRLKGKRDSVEAHRL
                     LALGADDPELLRRFDVPFVGRATERQALDAALERAARGDRAGLLRVTGEAGIGKTRLVR
                     EWLALRSASGALVYGAGRCRSYGDHGTLAPLADAVRSLVAAGSAPTPGPGYGHASGPAD
                     DAKDAVGGLGVDDTMALLSGGLLRDGTPNAPFEDMCAALTAVLERAALVRPVVLVLDDW
                     HAAAPLLVRTVRRLADGSGCAGVLLLCAGRPDGPDEGDGPIGGDEPIGGAGQLQLTGLP
                     PDEAARLAAGLAGPDGGPAPVDDRLLARAGGNPLYLEQLLVGDRADPAAASRPGEPVAA
                     EEDLPPTLQALLGARIGALARAERGVVDLAAVIGREFTAPELVRLELSVRAGEGHDAGQ
                     LAGATGAAGAAPEHRRYVEEALAVLGRRRLVESGPSDDREAAAYRFSSGLVHEVAYASL
                     SKRAKAERHAWAAELPSVLRSGDGAVGGHLERAYRYRAELGLLDDPARRLRERAAAALG
                     RAGAQAAARSDLHWAHGLLERAVDLCPGDPAATRRLGEVRVALGHAGEGAELLRRVRDS
                     GADAVEAAHARLALAVLDPGGPGPGPAAVARTVLPVFEAAGDSTGRARAHLRLAQQFQR
                     SGRHEEAERDQARALEHAVLAGAEPERAGALGAIGVSLWRGPVPVPAAVIRCRALLAAH
                     GAGSAHGPGHPQLPAGGAVRAPEPARRGVPLPGRGGTAGREAGVRGGGGVPSGVPGDGG
                     GAARQRRNGPGPARPGGRGGPAHGCGRDADGGGTGRGPAGAGRGPGGPGCRPAGGRRRH
                     IGAEPGGRGGSGGAAGPAGGAGPPGGGGGTRGPGGPGLAAHRLPAGAGDGRAGPGAGAR
                     RPGPVAGGRGLGPVGRGALHGQGASAGGAPGLRLPRESAPAHGHDEGEEL"
     gene            28925..29851
                     /locus_tag="MWG59_RS11915"
                     /old_locus_tag="MWG59_11915"
     CDS             28925..29851
                     /GO_function="GO:0008236 - serine-type peptidase activity
                     [Evidence IEA]"
                     /GO_process="GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_S8"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1075: alkaline serine protease, subtilase family"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006124651.1"
                     /locus_tag="MWG59_RS11915"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MWG59_11915"
                     /product="S8 family serine peptidase"
                     /protein_id="WP_176739560.1"
                     /sec_met_domain="Peptidase_S8 (E-value: 3.2e-21, bitscore:
                     74.7, seeds: 43, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTTTEPERTGPGEPRPAPGARRAPGQGLTWSLRGRGPEDVPVLAD
                     PGPPLGRPAGPATGRGVRVCVVDSGVERDHPLIGPLAGSWVVVKDAESGGITVEPTTTG
                     DTCGHGTACAGIVRRTAPECEIHSVRVLGERFSGTGDVLMAGLRWAVEQGFDVINLSLS
                     TTRTRFAQELHSLADSAYFARTVIVASAHNTPVESFPWRFASVISVGSHQEDDPELHLY
                     NPDPPVEFFGPGQNVTVPWLGGRTIRTTGNSFATPYVAGLCARVLSAHPRMTAFQLKNA
                     LYLSAANVRHAPRPSTAAGDIRDDSEN"
     gene            29835..30458
                     /locus_tag="MWG59_RS11920"
                     /old_locus_tag="MWG59_11920"
     CDS             29835..30458
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018959339.1"
                     /locus_tag="MWG59_RS11920"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MWG59_11920"
                     /product="GAF domain-containing protein"
                     /protein_id="WP_097935711.1"
                     /transl_table=11
                     /translation="MTPRTDSAPSLSPTAAAPDADAPRSELLQSVVDVARAIFGAEASS
                     VFLLDEEADELVFQAVSGQGEEFLVGRRFPAGRGIAGWVATSGEPMVVDDLSADPAFDR
                     SLAESTAYVPNSLMAAPLISDSRILGVLEVLDPSPQARSGVRELDLLAMFARQAAAALR
                     VITPERVREAEQRAASGAGVLEGARREDALKLLGSLERLLRGTG"
     gene            30535..31323
                     /locus_tag="MWG59_RS11925"
                     /old_locus_tag="MWG59_11925"
     CDS             30535..31323
                     /GO_function="GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018959340.1"
                     /locus_tag="MWG59_RS11925"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MWG59_11925"
                     /product="sugar phosphate isomerase/epimerase family
                     protein"
                     /protein_id="WP_097935709.1"
                     /transl_table=11
                     /translation="MKLAFSTLGVPGTPVSEVVRLAAGNGYRGVELRVHPEEPVHLGLS
                     SLERADVVEEFKAGGVEILALAGYVRAAAEGDDEPVLAELSELVKLARDLGASYVRVFP
                     GGGDQEQAEADATAARRLGAAAPAAADMGVSILLETHDSHRAGLDAARVVAAVGHPRVG
                     AIWDVLHTWLAGEEPAASHAVLAPHLGYVQVKDVASADDLTPVALGSGVVPLADCLDGL
                     DPDTWVCWEYEKRWHPGAPELPGLLGAGREHLLRLGAPKQ"
ORIGIN
        1 gcgcgcatgc cgggcgtgga cgcggccgtg ggtctgctga acacccaggt gctggtgccg
       61 gtgggctccg gggagttcag ctcgctccag ggcgcggcgg cacagggtgt caccggtacc
      121 ggtgcggagc tggcgaaggt gcaggacctg gacgtacgcg aggggagcct ggaccggctc
      181 ggcgaggggc gcgtcgccat cgaccggacc ctggcggact cggcggacgt cggcgtcggt
      241 gaccggctcc cgctccacct ccccgacggt acgaagagcg cccccgaggt cgtcgcggtg
      301 tacgggcgcg gcctcggcct ggccacggtg accctggacc gggcgtccct ggccggacac
      361 gtctcgtccg gcttcgacag cacgctgctg gtgcggggcg gatccgggcg gtcgctcgcc
      421 gccctgggcg aggtcaccga cgcctccggc ttcgcagcgg agcggagcct ggacgcgaag
      481 ctgggcgcgt ggtccaacaa cacgatggcc ggggtcctcg gcggcttcgc cgcgatcgcc
      541 gccgtcaaca ccctggtgat gacggtcctc gaccgccgcc gcgaactggg caccctgcgc
      601 ctggtcggct cgacccggcg ccaggtgctg gggatgctcc gctgggagag cctgctggtg
      661 tcggcggtcg gtgtggtcct cggctccgcg atcgccgcgg ccaccctggt cccgatgatg
      721 cgcggcacga ccggcgagtc gccgtacgtg ccaccgctgc tctacggctc gttcgtgtct
      781 acggctcgtt cgtggccgcc gccggtggac tggccctgct cgcggtcacg ctgccgggac
      841 gggcggcgct gcggcggtgg tcatagggcc ggccggggtg ccgggcgccg ccctcgcgct
      901 cagcccgtgc tcgccgcgac ctcgctgcgc agttgcggca gcttgtcgtg cagcacgccc
      961 gggcagaggg tgtcgccgaa gtccttgtgc ccgtagatgc ggctcggcgc gatgccgtac
     1021 tggtggcagg tgtacgcgca gagcgccacc aggacctccc actgggcacg cggcggttgc
     1081 gctccgtcgt ggtacgcgcc ctcgttggcg atgccgatgc ccgccccgtt ctggccggag
     1141 gtgtgcgcgc ccatgacgaa gtcccggccg ccccgcagtg tgctgaggct ctggtggcgg
     1201 ccctcggtga tccagccgcc ccggctgacg aggaagtggt agccggtgtc ggtccatccg
     1261 ttcttgtcca tgtgcaggtc ctggacccag tgggcgtggc tgtgggcctg ggcacgggag
     1321 acgtcggagg tgttggcgct gaccgtgtgg tgcacgacga tcatggtggg ccgcttcccc
     1381 accaggtcga tcgggccctg cggcggacgg gctttccact gggacgtgct gtcgatgtcc
     1441 ggttcgacga cgtcgagggc gtgggccgta cccggtaagg cggctgccgc gaggccgccg
     1501 gcaccggcga gcaggacgtg acggcgggac ggctgaggaa ggttcacggc ggactcctgg
     1561 cgtgtggtcg ttccgggcct gccggacagc gacagtgaca acggtggtga cagtgacaac
     1621 ggcggtggct gtggcaggtg gcggcggtac ggccgggcgg gggctgtact cacccggccg
     1681 ccgcgagtgc ggggccgcta aaccgtgttg ttggcgaggg cctggagccg ggcgaagctg
     1741 ccgttgaact tgttacggtc cacgtcaccg gagactccgg cgacccgccc cgtggccgag
     1801 tactgccaga tcgtccaggt ggggaagccg ctggggatgt tcgggctact ggtgccccaa
     1861 tgagccaccc agagaggcga cttggtcgcc ataccggtcc agctgccggt gcaggtgttc
     1921 caccagctgg ccgtcgtgta gatcacgacg tcccgggtgg tgcgcgcctt gtacgtgttg
     1981 tagaagtcgt tgatccacgt gcgcatctgg gtcgtggaga ggccgtagca catggcgccg
     2041 tacgggttgt gctcgatgtc cagcaccccg gggagggtct tgccgtcctt ggaccatcct
     2101 ccgccgccgc tcgcgaagta gttcgcctgc gtcgccccgt tggagacgtc ggggcgggcg
     2161 aagtggtagg cgccccggat caggccggcg ttgtaggagc cggtgtagtt ggcgctgaag
     2221 cggctgtcct tgtaggtcgt gccctcggtg gccttcatgt aggcgaagtc gatgccagcg
     2281 gccttcaccg agccccagtt gatcgcaccc tgccagtggg agacgtcgat gccctggacg
     2341 ccgctggtgt ccatcggtgt cacgccgccc gccgccgagg acgcgggacc ctgctcgatg
     2401 cgggtccccg cccccatcca cgcatgtccg gaccggaccg gctcatcggg tgcgggcggc
     2461 gcggcgacgg ccgtgcccgt gccggtcagg atcagggcag cggtactggc gagcgcccct
     2521 gccagcaggg ctcctcggga tctcctgagt cggcgggacg gagaacggta cgcgggcata
     2581 gccacctccg ggcacgttga cgggaagaga tccatggcat ccgattaccg gacgccatgg
     2641 acatgtcatg agtaacgcac ggagcggggg aggcgtaaag aggctctacg gtctagacct
     2701 gtgccgccgc accccacctg cgagaacgtg tcggaacggc gaaaattttc actcctgaag
     2761 gtccccggca cccgatcccg gcccatgggc gcacgaaggt acgcaagagc ggcgaccggc
     2821 cgccggacaa caccttgccc ccagtactca aatttgacta cgctgcccgc atgatcgaga
     2881 cgaccatccc gatgctgccc tgccgtacct cgctgatcga gaccaccgtc gacttctaca
     2941 ccgccctcgg cttcgcgacg acgtacctgc agaagagccc gtacgcgtac gcggtcgtcg
     3001 agcggggagc ggtcgaactc cagctgtacg gcatgaagga gtacgacccg gcgtcctccc
     3061 actccgggtg ctacgtcctc accgatgacg tggacggcct gcacgcggcg ttccgggcgg
     3121 gcctcaagga ggcctacggg cgcgtcccgg cacgggggct gccgcgcatc ggtccgttga
     3181 aggacatgtc gtacggggtg cggcagttcc tggtgaccga cccgaccggg aacacgatcc
     3241 ggatcgggca gccgatcagc gaggaccaga accaccggcc cgcgcccaag gagaccttcg
     3301 cccgcgccct gcacatggcg gacctcttcg cggactccaa gcaggatctg ccgggcgcgg
     3361 cgaagatcat cgaccgggtg ctggggctga cggacgagca cccgactccg gcgcagaagc
     3421 tgcgccttct cgtcctgcgc ggggacatcg cacagcgcat gggtgacgcg gagaaggccg
     3481 gcgtgctgct ggaagaggcc gcggcggtcc ggctcgggcc cgaggagagg gaagccgccg
     3541 cggacacgct ggccaggctc gcggacctgc ggggctgatc agccgaaggg ggcgccggtg
     3601 acccaccccc gctgggcccg gccccggttc acctcggggg gtcctcgccc gtcaggccgt
     3661 cgacggactc ccggatgagg tcggcgtggc cgacgtggcg ggcgtactcc tcgatgagat
     3721 ccaggaggat gcggcggagg ttcgggcgtt cgccgctacg ggtgacgtgg gcgccgagcc
     3781 ggtccagccc gccgcccgcg cggagcgccg cgtcgaccgt ggcccgggag cgggccgccg
     3841 attcctgcca gagggtgcgc agttgcccgg gggtgtcctg ggcggcggag cgataggccc
     3901 agtcggggtc actgtcccag tccaccgcgt cccagggggc gccgaccgga acaccgagcc
     3961 acagacgggc gaagtggctg tcctcgacgt gcgccaggtg cttgagcaga ccgcccaggg
     4021 tgacggtgga cgcgccgacg gtggcccgca gtccggcggc gtccaggccg gagcacttcc
     4081 aggcgagcgt ggcccgctgg cgctccagcg cgccgaggac ggctgccgcc tcggtaccgg
     4141 cgaggggagg ttcgggccag gcttccactg tgctctccgt catggcggac acggtagcgg
     4201 agccggaaca gcggaatggg gcccggcctc gcggccggac ccccctcgct ttcccctccc
     4261 gtcgggcctt cccgttcccc ccggacccct ccccggaagt acccgacgcc atgtgtgaca
     4321 cgggagggta cgcaaaggtt gcagcccttt acgatctctt tgccatcggg gcggcgcagg
     4381 ggctctcagc aggcatgttg cacatagcgc tccgccactt ccgccagtgc ctccgccccg
     4441 tcgcgggccc acagcgcctc gttgaagatc tccacctcga tcgggccgtc gaagccggcg
     4501 gcctccacga gacggcggaa ctcacggaag tccacgcttc cgtcgcccag ttggccccgg
     4561 cccagcagga cgcccgccgg gagcggggtg atccagtcgg ccagctggaa ggagtggatg
     4621 cggccgcccg cacccgcgcg ggcgatctgg gcgggcgccc ggtcgtccca ccagaggtgg
     4681 taggtgtcga cgaccacccc gacctggtcg gccgggaagc gttccgcgat gtccagggcc
     4741 tggccgagcg tggagacgac gcagcggtcg gacgcgtaca tcgggtgcag cggctcgatg
     4801 gccaggcgta cgccgcgcgt cgccgcgtac ggggccagct ccgccagcgc ctcggcgacc
     4861 cgctcccggg ccccgtacag atcgcggctg ccgggcggga ggccgccgga gaccaggacc
     4921 agggtgtcgg tggacagggc cgccgcctcg tcgatcgccg cccggttgtc gtccagggcg
     4981 cgggcgcgtg ccgcggggtc gagtgcggtg aagaagccgc cccggcagag actggtgacg
     5041 gtgagcccgg catccgccag gagcctggcc gtgcgctcga cgccgtacgc ctgcaccggg
     5101 tcccgccaca gacccaccat gccgatgccc gccttgacgc agccctcggt cagctcgggc
     5161 agcgaccact gcttgatggt ctcctggttg agcgagaggc gggagagccg gccgtcggtc
     5221 atcgtgtgcc tccgtggacc gcgagcagtg agcgcatacg gtgttccgcc aggtccgggt
     5281 ccgggaacag gcccaggcgg tccgccagtt cgtacgcctt cgccagatgc gggagcgagc
     5341 gtgccgactg gagcccgccc accatcgtga agtggtcctg gtggccggag agccaggcca
     5401 ggaacaccac gcccgtcttg tagaagcggg tcggcgaccg gaagagatgg cgggagagct
     5461 cgaccgtggg gtccaggagc gcccggaagc cgtccacgtc tcccgtgtcc agcacccgta
     5521 ccgcgtgcgc cgccagcggt cccagcgggt cgaagatgcc caacagggcg tggctgaagc
     5581 cgcgttcgtc gcccgcgatg agttccgggt agttgaagtc gtcgcccgtg tagcagcgca
     5641 ccccgcccgg gaggcggcgg cggacgtcga tctcgcgggc cgcgtccagg agggagatct
     5701 tgatgccgtc gaccttgtcg gggtgttcgg cgatgacctt gaggaaggtg tccgtggcgt
     5761 cgtcgaggtc ggcgctgccc cagtagccct ccagggccgg gtcgaacatc gggcccagcc
     5821 agtgcaggat caccggctcc gacgcctggc gcaggagatg ggcgtacgtg gcgaggtagt
     5881 cctccgggcc gcgcgcggcg cggaccagcg cgcgggaggc catgaggatc ggctggacgc
     5941 cgttctcctc ggccagggcc agctgctcct cgtacgccgc cgtgacctcg gccagggtgg
     6001 gcgtcccgcc gccgggcagc tggtcggtgc ccacgccgca ggcgatcctg ccgcccaccg
     6061 ccttcgcctc ggcggcggag cggcggatca gttcggcggc gcccgcccag tccaggccca
     6121 tgccgcgctg cgcggtgtcc atggcctccg cgacgcccag gccgtgcgcc cacaggtggc
     6181 ggcggaaggc gagcgtggac tcccagtcga cggccgccgg gtcgtccgga ccgatgtccg
     6241 cgtacgggtc cgcgaccacg tgcgccgccg agaagaccgt acgggaggtg ggggccgccg
     6301 ctccgggagc gaggtcgagc ggtgtcgcgc ggggcgtgta ggggccctgc gggaggtgga
     6361 tcgtcatgtc agcggccccc gccggtgccg cgcaccggtc gtgcgggtca cagggtcagc
     6421 tccgggatgt cgaagcggcg gccctcggcg gacgacttca gtcccagctc ggccagttgg
     6481 acgccccggg cgccggccag caggtcccag ccgtacggct cgtccagggc cacatggcgc
     6541 aggaacagct cccactgcgc cttgaagccg ttgtcgaact gctggttgtc cggcacctcc
     6601 tgccactggt cgcggaagga ctcggtgacc gggaggtccg ggttccagac cggcttgggg
     6661 gtcgacgagc ggtgctgcac ccggcagttg cgcagaccgg cgacggcgga gccgtgggtg
     6721 ccgtcgacct ggaactcgac cagttcatcg cggttgaccc ggaccgtcca ggaggagttg
     6781 atctgcgcga ccgccccgcc cgccagttgg aagatgccgt acgcggcgtc gtcggcggtc
     6841 gcctcgtacg gcttgccccg ctcgtcccag cgctgcggaa catgcgtctg cacatgggcc
     6901 gttacggagg tgacctggcc gaacagctcg tggagcacgt actcccagtg cgggaacatg
     6961 tcgacgacga tgccgccgcc gtcctccgcg cggtagttcc acgacgggcg ctgggcctcc
     7021 tgccagtcgc cctcgaagac ccagtagccg aactcaccgc gcacggacag gatctcgccg
     7081 aagaagccgc cgtcgatcag gcgcttcagc ttcagcaggc ccggcaggaa gatcttgtcc
     7141 tggacgacgc cgtgcttgat gcccgcgtcc cgggcgagcc gggccaggtc gagggccccc
     7201 tcgacgtccg tggcggtcgg cttctcggtg tagacgtgct tgcccgccgc gatcgccttc
     7261 ttgatcgcct ccacccgggc cgaggtgacc tgggcgtcga agtagatgtc gatcgtgtcg
     7321 tccgcgagga ccgcgtccag gtcggtcgac cactcggtca ggccgtggcg ctcggcgagt
     7381 tcctccaggg cgtgggcacg gcggccgacg agcacgggct cgggccacag cacctcgccg
     7441 tcgccgagat ccaggcctcc ctgctcacgg atcgcgagga tcgagcgcac caggtgctgc
     7501 cggtatccca tgcgccccgt gacgccgttc atggcgatgc gcactgtcct gcgtgtcacg
     7561 aaggtccctc catacagccg tagcaagcgc tttctatcag agatgacgct agcctgccga
     7621 cagcggccgg acaagagggg gccgcacgtg atctcacgga ggacagcgat gacagtcacc
     7681 ctggcggatg tggcggcccg cgcccgggtg tccccggcca ccgtctcgcg tgtgctgaac
     7741 ggcaactacc cggtggcggc gtcgacccgg gagcgggtcc tgcgcgcggt ggacgacctg
     7801 gactatgtgc tcaacgggcc cgcgagctcg ctcgcggcgg ccacctccga cctggtcggc
     7861 atcctggtca acgacatcgc cgacccgttc ttcgggatca tggcgggggc ggcccagacg
     7921 cagatcggcg gccccgggga cggttccgga cgggcgggcg gcgagaagct ggccgtcatc
     7981 tgcaacaccg gcggctcccc ggagcgcgaa ctgacctacc tcaccctcct ccagcgccag
     8041 cgcgccgccg cggtcgtcct caccggcggc gcggtcgagg atccggcgca ccgggccgcg
     8101 atgtccgcga agctgacgaa gctcgcggac gcgggcaccc ggatcgtctt ctgcgggcgg
     8161 cccccgctgc ccgaggggga cgcactcgtc gccgcgctcg cgttcgacaa ccggggcggc
     8221 ggacgccggc tcgccgagca tctgatctcg ctcggccacc gcaggatcgg ttacgtcgcc
     8281 gggcccccgg agcgcaccac cacccggcac cggctggagg gccaccggga ggcgctgcgc
     8341 gcggccggcc tggacgccgc cccggacgag gccgacgggg gccggggctc ggacgatcag
     8401 gaccggctca ccgtgcacgg gccctacgac cggcgctccg gctacgaggc caccctcgaa
     8461 ctcctgcgca gggcaccgga cgtgaccgcg atcgtggccg ccaacgacac cgtggcgctg
     8521 ggcgcctgcg cggccgtacg ggaccagggg atgcggatcc cccaggacat ctcggtcgcg
     8581 ggcttcgacg acctgccgtt ctcggtggac gcggtgccgg ccctcacgac ggtgcggctg
     8641 ccgctcttcg aggcgggcgc ccgggcgggg cggctcgcga tgggcaagga gaacccgccg
     8701 cccggcggga tcgcgaccat cgcggccgag ctgatgatcc gggggtccac ggcggcgccg
     8761 cgcgggtgag ccggcccggg gatgccccct tgccccctgg gcccgtcggc cccgacggga
     8821 ggccctagcc gagcagtccg agcagccgtc ccagcgcgtc cgcgacgggc tgggccaccg
     8881 ggccgaccgc ggtggtgagc tgcccgagcc gtgccagggt gaggccgcgc tcggtcatgg
     8941 cctcgcggtc cagggcgagc acgggcaggg tctcctcgac cgtgcgggcc tggtccgggg
     9001 tgaggtgggc ggtgagctcg cggagccggg cggtcaactc ccgcacagcc gcgtggagtt
     9061 cggggtcctg ggcggcgccc acgtagccgt tgttgatgcc gatgttctgg gcgccggtct
     9121 ggttgaagac ggggccgttg taggtcgagt ggtgcgtcgg ttcggtcaca gcctgatccc
     9181 cgtgttctga ccaccgttct ggttgaagac ggggccgttg tagttgttca gctggtgcac
     9241 gtaggccgtg aactcggcct ccgggtggtc gatcgcgtgg actatccgcc cggcgatggt
     9301 ccgcagctcg tccacgctcg gcagcgtcac gagtacgcgg gagctgccgg ccgtctccac
     9361 gaccaggacc ggcgtctccg gtgcgattag cgccttgacg aaatagacga ccagaacgat
     9421 cagcaggacg agaaccggag cccagtcggt caccgagtag acgaaggcca ccagccccag
     9481 gcccagcagg aagcggagga cgttgcggtc cggcttgatc ttgatggcct cgacccgggt
     9541 gaggttgtgc agcggcaggg ccgccgagcc gatccagagc atccggcgct tgaccgcgat
     9601 ctccaggacg cctcccggac gcggcagcgg cggtagcggc ggcggctgcg agggaggccc
     9661 ggccggagga tccggcggtg gcgaggacgg cggtggtgag gacggcggtc cggtcggtgg
     9721 cgtcgttggc tgcccgaagt tccccgtgct gtccatgcgt tcccccgtgc actcgtcact
     9781 cacccccgca tgcgcgggag ccccattaag catcagcccg gctccgagcg gcaggcgaga
     9841 aaccgccaat cctcgctcca cggctacgcg ttaccggcgt ctgcgcgccg gggcgcgaaa
     9901 gatgggggcg actcccccat gcgcccgcac ccgctccccc gccacgatgg acgcgggcgg
     9961 cccgaccggg gcccgcccgg gaccggggag gtgcggagcg atggcggaga aggatctgat
    10021 cgacagaggg acggcccgtc gtcccgcccc tgctgtctcc gtcgtgtccg cgcccgcctc
    10081 ctccgtcgcg tccggcacgc ccggcacgtc cggcacgtcc ggcacgtccg gcaccgccgc
    10141 catcgtcgcc ttcgggggtg cggccgggga gccgtggtgg cttccggggg tcgtcggcgg
    10201 cagcgattcc ggcgaacccg gctgggcggt cttcgcccgg gaggccgtcg cctcggcgcc
    10261 gcgtgacgtg gtggtcgccg accgggccta ccccgggctc agcggcttcg ggccggtcgt
    10321 cgcaccgttc gtcgaggcgg cgacgcggcg gctccgggac gcactcgcgg acgacggccc
    10381 ggcggtcaac ggcacggtgg gcggacgggc gacaaacggc ccggcggcag acggctcctc
    10441 ggccgtcctg gcggacttcc ggcggcagct gacgcgtcga ctgtcccgga tcgctgggcg
    10501 caccctcgtc acggaactgc acgaggcccg gcggctgggc cggttgcgcg gcgaggggtc
    10561 cgaggagcgc ttccgggact tcgtccggcg gaccgcccgc cgcgacggcc tcgccctgct
    10621 cgtcaccggc taccccgtgc tggcccgcct cctcgcgacg gcctgcctga acgcggggga
    10681 cgcgttcgcg gagatggccg cgcggctcgc cgccgaccgg catctgctgg ccccgtcggg
    10741 ggtgctcggc gaccgggccg gttccccgga gagcgggctc ggcgggaacg cggggcccgg
    10801 ggcgctcacc ggcgtcgagg ccggggcggg cgacagccat cgcgggggcc ggtcggtcat
    10861 gctgctgcgg ttcgccgacg gcgcccggct cgtctacaag ccgcgtccgc tcgcggcgca
    10921 ccggcacttc aacaccctgg ccgagtggtt cggttcgctg cccggagccc cggaactgcg
    10981 ggtcctgcgg gtcctggacc ggggggacta cggctgggcc gagttcgtcg aggagcggcc
    11041 ctgctcctcg gcggcggaga cccggcagtt ctaccggcgc cagggtgcac tgctggccct
    11101 gctgcacacc ctggacggta cggatctgca ccacgagaac ctgatcgcct gcggcccgca
    11161 tccggtcctg gtcgacgtgg agaccctgtt ccacccgccg ctggggcccg cgaggtccac
    11221 cgatccggcc gcccgggccc tgcacgactc ggtccaccgg gtgggcctcc tgccgcagtt
    11281 gctcgtcggg gacacgaccg cgctcgacat gtccgccatc ggcgggggcc gggccgcgtc
    11341 gtcgccgatc gagaccgccg actgggcgga ggccggcacc gaccggatgc ggctggtgcg
    11401 gcgggcgggc cggttcaccg agtccgccaa ccggccccgg ctgggcggag tggcagcggc
    11461 tccctccgcg tacaccgacg ccctgtgcgg cggtttccgc gccggttaca ccgcgatcag
    11521 cgatcaccgc gccgaactcc tcggtgagga cgggctgttg cggctcttcg ctcgggacga
    11581 agtgcgcgtc gtgccccggc cgacctggac atacacgacg ctgctggacg agtcgaccca
    11641 ccccgacctc atgcgggacg ccaccgaacg gcaccaggtg ctctcgctgc tgcgaacccc
    11701 gctcctgggc gtgcccgcgc tgcccggcgt ggaggacgag gaggtcgcgg agctgtggtg
    11761 cggcgacgtg ccggtgttcg gcacccggcc gggctccacg gagttgtgga gcggcaccgg
    11821 ccgtacggtt ccgggggcgg cccccgaccg gccctcgtac gacaccgcac gcgatcggtc
    11881 cccgcacgac ctggccgccg gcgacgccgt cggccccacc gggctggcgc gcgtggaggc
    11941 gaaggtgcgt gcgatggaca ccgtggaccg ccaggatcag gaacggatca tccgggccgc
    12001 catggtgagc acctcgcccg agccgccgca ccgggcgggt ccgggcggcc ggtcgcggag
    12061 tgcggcgacc gcgccggagc ccgagcaact gctctccgcc gcacggtcgg tgggcgacca
    12121 gctcgtctcc ctcgcctacc ggcacgagag ccgcaccaac tggatcgggc ttgagctgct
    12181 cggcgagcgc tactggcggc tcacgccgat ggcggcggac ctcgcgggcg gttacaccgg
    12241 gcccgcgctc ttcctggcgc aactggccgc gctcaccggc gcctcccggt acgcggaggc
    12301 ggcgcgcgag gcgctcgccc cggtcccggg gctgctggac gcgctgcacg ggcgggccga
    12361 cgaactcggg tccctgggct ccggcgcctt cgcgggtctc ggcggcatcg cgtacgcgct
    12421 gaccgaggtg ggcacgctcc tgggcgaccg ggatgtgctg gacctggcgg gtccggccgt
    12481 ccggttgagc tgcgcggcga gcgcggccga ggacgggtac ggggtgcgcg gcggggcggc
    12541 gggcgggctc gtctcgctgc tcgcggtgca ccgcgcgacc ggccgcccgg aggcttggcg
    12601 tggcgccgag cgctgcgccg agcggatcgc cgccgccccg ctccccggct ccgggggctt
    12661 cgccgacggg gcggcgggga tcggctgggc gctgctgcgc ttcgccgggg cagggggcga
    12721 cgcccgccac cggatcgccg ggctggaggc cctgcgccgg gcgacggccg gagcggccca
    12781 tgtaaccacc gccgccaccg ccggagcgcc ggacggaacg accgccggaa ccaccgccgg
    12841 agcgccgcac ggagcgaccg ccgggacgac ccgcgaagcg ggagccggag cggccgccgg
    12901 gccggcctgg tgcggcgggg tggccggcat cgcgctggct gtcgcggaca gccccgacgc
    12961 gctggcggac ccggagctgt ccggctggct cgcggcgcgc tccggcgagc tggcgggcat
    13021 cggtccgctc gccgacgaca gcctgtgcca cggggagtcg gggctgctcg aactcctcgg
    13081 ccacggctcg ctgcccgccg cacggcccgc gtggatgcgc cgggccggga cgctgctggc
    13141 ctcggcggac cgggcgggac cgcagtgcgg gacgcccggc cgcgtaccgc acccggggct
    13201 gctcaccggg ctctcgggga tcgggcacgg gctgctgagg gccgggttcc ccgaccggat
    13261 cgggtccgcc ctgctcctgc gttcctcccc ggctcccctg accgaaccac ggctttcctg
    13321 accgaaccac ggctttgacg acgaccatca ccaccaccac ccagaggatg aggcagagat
    13381 gaagcagttc ggcgaatcgg ccctgcaggc gtccggcgag atcgcgcacg aggggacgcc
    13441 cgagcacccg gccgggcaga tctccctggg gtccaccgga ggcctcggtg cgcgcagcag
    13501 acttctcagc gcctcggagg gcgagagcgg ctacagccac gacctgccgt ggaccaccat
    13561 gacggccccg tggtgaccgg ttcctgccaa ctcaaccgca aataagcctc attggcccgc
    13621 tgccgtagga gttgcggctc cagtaacctg cggccatgcg agccacttcg ccggtcatcg
    13681 tcgggcggga cgaggagatc ggactgctga gcagcgccct ggacgccgta caacggcgtt
    13741 cggggcgcgc gctgttcctc gtcggggaag ccggtatcgg caagtcccgg ctggtgggcg
    13801 agtgcgccta ccgggcgtac gggctcggta tgccggtgct gcgcggccgg gccacctcga
    13861 ccgggctcgt cgtccccttc cgcccgctcg cggaggcgct ggcctcccgg ttccgggccg
    13921 cgggcacgcc gaccgatccc gagctcgcgc cctaccatcc ggcgctggcc cggctggtcc
    13981 cggagtggcg caggggcggg tcccccggct atcccgagac ggtcgtggag ctggccgagg
    14041 cgctgctgcg gctgctgtcc gtgctgggcc gggaggcggg ctgcgcgatc ctgctggagg
    14101 atctgcacga ctgcgacacg gagaccgtcg cggtcgtcga gtacgtcatc gacaacctgg
    14161 ccgatctgcc catcctgttc ctgggcaccc tgcgtccgga gccgggggcc gccctggacc
    14221 tcgtgcgctc caccgaacgc cggcacgccg cgaccgtacg ggagctgggc ccgctccgcg
    14281 acgaccgggt gcgggcgctg acgggcgcgt gtctggaggc gcggccggag gagatacccg
    14341 agtcggtgca ccggcggctg gccgaacgcg ccgcgggtaa cccgtacttg ctggaagtgc
    14401 tgctggcgga cctgctggac accggccggc tccggcggac ggacgacggg tgggtggcgg
    14461 cggagcagcc gggcggttcg gttccctcgg acatcgtccg cagctgggcc cgcaggctgg
    14521 agcggctgga cgagccggtg cgggacctct tactggcgtc ggcgaccctg ggcagccagt
    14581 tctcggtgac cgtgctccag accgtcaccg ggttcgagga ccgggccctg ttcacgcatc
    14641 tgcggtcggc ggtggaggcc ggtgtcatcg ccccggacgg cgccgccccc gaccgctaca
    14701 ccttccgtca ctcgctcacc gccgaggccc tgatctcctc gctggctccg gccgagcgcg
    14761 cctcgctcgc ccgccgcgcc gccggggcca tcgaacactc cgggcagccg ctggacgagg
    14821 acggccgtca gctcgtggcc tcgctgcaac tggccgcggg caaccgggcg ggggcggccc
    14881 gccagttcgc ggaggcggga agacggatgc tcgcttcggg ggcgcacggc tccgccgtgg
    14941 tgctgctgga gcgggcgcac ccgctggccg ccgagaccga ccgggccgcc gtcgccgagt
    15001 cgttggcggt cgcccgtgcc gagggcggcg atctggacgc cgccctggcg ctggctgacg
    15061 cgctgccgcc ggttccggca cgttccgagg ccgccgcccg gcgcggcctg atccatatcg
    15121 aactcgcctg ggctgcggtc atggccgagc gcaccgccga cgcggcgctc caggtggaag
    15181 cggcccgtgt cctgctcggc ccgtcgccgc cgccgggccg ccgggccgcg ctcgtggtgg
    15241 tcgacgggta tctggcgctg cttcccgggc acgggcagaa gccccgggat ccggcggatt
    15301 ccgagcgggt cgttcgggag gccgcggaga ccgccgaggc cgaggggctg cccgtggtgg
    15361 cctgccaggc ctggcagttg ctggcgctgc tgcggcgcga ggagggcttc gacgcggcgg
    15421 acgccgcact ggagcggatg ctgtcgatct ccaccgaaca cgccctgccg gtctggcggg
    15481 tggaggcgct ggtgcggctc ggggcgaacg ccttcatgcg gaccggggac gccgcccggc
    15541 tgctctccgc gcgggcggcg gccaccgagc tgggcgcgct gctgctgacc cgtacggtcg
    15601 acgggctgct cgcgatgaac gcggtgatgt gcgcccggtg ggaggaggcg caggagatca
    15661 tcgaccgctc ggcggaggcc agcgcccggg tcggtgaccg gtccgcccac cgctatctgc
    15721 tgctggccgg ggcgacgatg gccgcgcacc gggggcggcg gcgggagatg gaccgggcgc
    15781 tggccgcgtt ccggcgggcc gggggcgagc agtcgctgct ggtgccgctc cggtcggggc
    15841 tgtgccgggc gttcggggcg ctcctggagg aggaccggga gcgggcggcg gcgggtctgg
    15901 acgaggcgct ggcctgggag gcggaccacc cgagctacta ctacctgagc gggcggtacg
    15961 ggctgcgccc gctgctgcgg gtgctggccg gcgaggcgga ccgggcggag ctggcggagg
    16021 cgcgggcggc tcccgggggc gctctcgcct ggaaccggca gttcctggag ctggccgacg
    16081 cggtgctgct gggccgggag ggggacccat ctggggccgc ccggctgatg gcgtccttcg
    16141 atgtgcggtc cgcgcccttc ccggtcgccc gccacttggg cctgcggctg gtcgcggacg
    16201 cggcccgggc ggacgggtgg ggcgagccgg tggcgtggct gcggtccgcc gaggagtact
    16261 tctacggggc cggggtgcag gcggtcgcct ccgcgtgccg ggcggcgctg cggcaggccg
    16321 gggcgagtgt ggggcagcac cggggcggct gggaccggat cccgtcgccg ctgcggacga
    16381 gcggggtgac gccgcgcgag tacgaggtgt tcgtcctgct gcccgagcgg cccgggaacc
    16441 agcagatcgc ccggcggctg tccatctcgc cccgcacggt ggagaagcac atggccagtc
    16501 tgctgagcaa gaccgggcgt gcggaccggg ccgcgctgtg cgagttcgcc gccgagtgcg
    16561 ccgtcgaacc ggcctgatga gggcccgtcg tgggcccgtc gtgggggccg gggcgggcaa
    16621 catgggggca gcgggccgtt tcggtcgggt gtccgggcgg aaaatgcgtg cggggccccg
    16681 atgtgcgggg gccggggcgg cagcaggatc ggggcgtgcg tacggcccag accgccgccc
    16741 gtccccgttc cggaggcccg ctgatgaccc gacctcccgt ccgcaccgct cccccgggtg
    16801 cggtgtactt ctccctgctc ggcccgctca ccgcccggct ggacggccat gagctgccgc
    16861 tcggcccgcg gaagcagcgc ctcgtcctcg ccacgctgct gtcccgcccc aacacccccg
    16921 taccggtgga ggtcctgacc gacgcggtgt ggccggacga tccgccgcgt accgcccgca
    16981 agaacctcca ggtgtacgtc agtgccgccc gcacccttct ggggccggcc gggcacgagg
    17041 gccgggaccg ggtggtgcac ggctgcggcg gctatctgct gcggatcgcc gagggcgagc
    17101 tggacaccct gcgcttcggg tcgctggccc gcgcggggcg ggcggcagcc gggcggggtg
    17161 atctggccgg tgcggcccgg ctgctgcgcg aggcgctgga cctgtgggag gggccgccgc
    17221 tgaacgacct gcgggactcc gccggggtcg ccgaggaggc ggggcggctg gaggcccgat
    17281 gtctgaccgt ctacgaggac tgggcggaga ccgagatcga gctgggccgg cccgccgtcg
    17341 cggtggacgg gctgcgggac ctggtggagc ggcatccgct gcgggagcgg ctccgggccg
    17401 cgtggatgaa ctccctgcac cagtcgggcc ggcaggccga ggcgctggcg gtgtacgacg
    17461 actaccggca gctgatggcg cgcgagctgg ggctggagcc gagcccggcg atgacggcgc
    17521 tgtaccgctc gatgctgggg cgtgggcgcg aggcccggcg gcccgccccc gcccgggagg
    17581 cggtgagtcc ggcggcgccg ccctcctgca ccgcggcctt caccgggcgc cccggggaac
    17641 tgcgtgacct gctggaggtg ctgggctgcg gcgaggagcg cgtggtggtc gtctcggggc
    17701 cggccggggc ggggaagtcg gcgctggcgc tgcgggcggc gcatctgctc gccgaccgct
    17761 tccccgacgg ccgggtccgg gtccgggtgc gccgggagga cggtacgacg cgcagccggg
    17821 cggagatcct ggcggagctg ggacggctgt gcggggtggc gggcaacgcc gcttccccgg
    17881 ggaacacggc ttccccggag ggcggggcgg gcggtgaccg cgcggcgacg gcggccctcg
    17941 cggacgcctg gcaggagtgg caggcccggc accgggcgct ggtcgtcctg gacgacgtgc
    18001 cggacgaggc gtccgtacgg gggctgctgt cccggtcggg gaagtgttcc gtactgatca
    18061 ccgcccgggg gcagttggcc gggctcgccc cggtccaccg gatcgcgctg ccggcgttgg
    18121 cggacggtga ggcgctggag ctgctgggga agctgatcgg ggcggggcgg ctgcgggcgg
    18181 acccgggggc ggcgttgcgg atcgtccggg cgtgcggggg gctgccgctg gcggtggagg
    18241 tgagcgggat gcggctggcg gtgctgcggc acctgccgct ggcggagtac gcggaccggc
    18301 tcgacgaccc gtcggccgcg ctggacgaac tggtcgccgg ggacgtatcc gtacggcacc
    18361 ggatcgcgtc cggctggcag gacctggcgg acggcgaccg gtgggtgctg gggcggctgg
    18421 cggggctcgc cgaggacggg ggcttcaccc tggaccgggc cacggaggcg ctgggctgcg
    18481 gtgagcgggc ggcgatccgg gcggtcgagt cgctgatcga cgcgggtgcg gtgacctcgc
    18541 ccgccgggga ggtcaccgcg cacgccgcgc tgtacgaggt gccgcggctg ctcggcctgt
    18601 acgcccacga gcgcgaaggc gtgtgagggg accggttccg cgcggaaggg ccccggggct
    18661 gtggcagccc cggggccctt ccgcgcgcgg tcgctcagcc cagggtgagc agctccagca
    18721 gatcggtctc cccggacccg tcgcgcccgt cgcgcccgtc ggtcccggta gttgcgccgg
    18781 agaggaagtg cagggacatc agcagccccg ccgctccggt ggccaggtcg gcggagcagc
    18841 gcatcagccc cgcccccggg acgaacagcc ggtcctcgtc ggcgaccagg tgccaggaca
    18901 ggttgcgtac ggaggcgagg accccggggg ccctgcggcc gtccggcgac agggcgcccg
    18961 ccacggccat gagccccgcc cggccggtga acaggcccgg ctcgcggacg aattcgaagg
    19021 cacagccctt ggccaccccg ggcagcaggg cggcgagtgc cgcgtcggcc gaggtgtgcc
    19081 cggacggggc gaacctcggc cgacgctgca ctggctccgg ggagtcgcgg cgggccagaa
    19141 aagcctgggc caccagggcg aaaccgccgc tcccctggtc caggtagagg aagtgccggc
    19201 ggccgtcctt cacctggacg gtgccgtccg gcatggtcac gcagtgggcc gcctccgcct
    19261 ccagggcccg gccggcggcc gccaggaact gttcgtcgcc ggtcagggcg tgcagttcga
    19321 ggtggagcag ggccgcaccg ctcagcccgc gcagcagccc cgccgacgcg ggcgcgcgca
    19381 gccccggcac ggactcgccc cgcaccagcc ggtccaggtc gtgggcggtg cgggccgcgg
    19441 cgtcgacgag gtcgtggtcg atcttggcgt cgggcgaccc gtcccccgcg cggtccggcc
    19501 gggccaggcg cagcgcggcg agcgcgatgc ccgcgcggcc gttcatcagg tcggccgagg
    19561 cggacggggg cgcggcggcg gaccgttcgt agagttcccg gccctcctcc cggcggccca
    19621 gcgcggacag caccaccgcc gtgcccggca acccgccgta gaggccgccc ggcgccgcgg
    19681 ggtcccggcg ccgggccgtg tcgacgagcc agtcggtcca gacgcgcggc accggggccc
    19741 cggtgcggtg cagggcgtgg agcaccccgg ccgccccgtg cgcgacgtcg ctgccaccgg
    19801 tcgagaagac ctcggggtcc ccggggaaga ggcggtcggt gcgctcgggc gtcgcccccg
    19861 cgtggatgcc ccgcagcagc ctctcccgca gcccggccca gtccggctcg ggaccgtcga
    19921 gcagcgcggc ggtctccctc tcgtggccgt cggtgctctc ggcggcccgc agcgccgagg
    19981 gccggcgcgg tcccgctccg gcgtccaggc cgtacctccg gcgggcccac cgttccaggg
    20041 tcagtgcctt ggcccggtcg tggccggcca tctccatgat gggcatcagc atgtagagcc
    20101 aggtcgccca gagggcgtag gcgtcggcct ccgcgccgac ggtcccggcg ggcgcctgga
    20161 gccccggggc tcccgccacc ggggtgtccc ggtcgtccag ggccgtggcg tactcgaagt
    20221 cgatcagggc cacgcggccg tcgggacgga tgatgatgtt ggaggggtgg aggtcgccga
    20281 agcgcagacc gcgcccgtgg acggcggcca gcgcctcggt cagccgctcg gtgaccgact
    20341 ccacccaggc gatgtacggg gcgagttcgg tggcggtgcc ggtgctgtgg agcagggcga
    20401 agcggccgac gatctcctcc aggagggtgg ccccctcgat gtgctcctcg atcaggaagt
    20461 ggtgctccca cacggtccgt acgccgtaca cctcgggaac gcagtccagc ccggccagcg
    20521 cggtcagggc ccggtgctcg cggtgcagtc gcgtcaccgc gtcgtcgccc gcctcgtcca
    20581 gcccgctgtg cggccgggcc tcgcggagca ccacctgccg gccggtctcc cggtgccggg
    20641 ccaggtagat gccgcccgcg ttggagaact ggagggactc ggagacgtcg taggggaagg
    20701 cggcgtcccc ggcggcggcg cgggccgcca gatgcgggcg cagcgcgtcg ggcacggtga
    20761 cccacggcgg tacccggaac accaccccgc gctcgtcggg caccagttcg cccgaggggt
    20821 ggcgcagggc cagcacccgt tcgccgtcct cgtcgaggca ccagcgggag acgaacgccc
    20881 cgtaccggac gtacaccggg gcgtcgccga tccgcaggtc gctgaggatg tacgggccgc
    20941 ggcggccggc gagggcgcgg gtcaactcct ccagcacccg caggaagacc gtctcgtccg
    21001 gcgggtagac cgtgatgaac ttcccggcgc ccgcacggga catgtacttg ccggacatca
    21061 gcaggagcgc ccgctcgctg cggaggaact tgaacggcac cccgtgggcc cggcagatcc
    21121 gggcggtgtc gagcagggtc tcctcggcct cctccgggac ggtggagacg tggatcttcc
    21181 agccctgccc ggccggttcg cggtcctcgg ggagcaggga ggtccacaga ccgccggcga
    21241 tccggcgcca gccctcgccc ggcggatcgg agtccagcgg gtagcgggtg ctctcgtcct
    21301 ggagccgggc gggggtctcg tagtacctgc gatcggcgag gcagtagagc tgggtctggt
    21361 ggagaccggg cacggggttc ctcctcaggg tgcgccggga cccgcggcgt cgggggccgg
    21421 ggcggtcgcc gggcgggtgg agacggttcc ggccggttcc ggcttctccc gggcggcggc
    21481 ggccccggcg cggacggagg gggcgagcgt cacgacggcg gccgagacgg ccagcacgca
    21541 gccgatcacg ccgaaggcgg cgctgctgtc cagtgtggcg agcaggaagc cgccggcgag
    21601 cgggccgaac ggctggacga tcgaggagag gaagcccgcg gcgctctgca cccgcccgat
    21661 ccggtcctcg ggagtgacga ccagcagggt cgagaggaag ccgatgctgg cgaccgtcga
    21721 gaggcacata cagagcgcgc agagcagtcc ggccaccagc gggctgctga gccaggccag
    21781 caccgcggcc gtccccacgc agctccagca ggtgatgacg atgagcgtcc ggacatggcg
    21841 ctccgccgcg aaccggggtg cgatcagcgc gccggcgagg gcgcccgccg agacgcaggt
    21901 gatgacgaag ccgccgccga gcccggagcg cccgctgtcg gagaagacgg cgagcgccga
    21961 gaaggtgagg gcgccgaagg agaagttcat gcccagcccg aagacgagca acaccgtccg
    22021 cagataggga agttgccaca ggaaggagag tcctgcggtg agttcccggc ggctgaacac
    22081 cgaacctgcc ctggtcctgg ccgccgagcg ggtccgcacg agcgccacac agacggtgga
    22141 gaggaacagc ccgaggaact gggcggtgaa gggcagggcc tggtgcacgc cgaacagcgc
    22201 gcctccgacg agcgggccga ccagccgggc cgtggaggtg cgcgcctgga gccgggcggt
    22261 cgccgtgctc atctggtccg gcggcacgac cgcgcgcatc agaccgaagg cggcgggggc
    22321 gtagacgctg ttcagtacgg cgccggaggt cgcgaccagc aggacgaggg ccatcggggc
    22381 gtgcccgttc cacacggcga gggcgagagc ggtgacggcc gccaggctgc ccacgtcgca
    22441 cagtcgcatc agccggcgac gttcgacccg gtcggccatg accccgcccg gcagcatcgt
    22501 gatcagcacg gcgcagacgg ccaccgttcc cacagcgccg gcctgcacgg cggagccggt
    22561 ctccttgagg atcagcaggg gcagcgcgat ggcgctcatc tggccgccca gagcggcgaa
    22621 gaggccgctc aaccagagca gccggaaatc acggttggaa cggagcggct cggccatcgg
    22681 ggctcccgtg gttcgtggtg gtcggctgtg cgggacgggg nnnnnnnnnn ccccggctgc
    22741 ggccgacgcc acggctgcgg ggcacgggcc ccgtcggacg tggccaagga ctcgcggaac
    22801 agtccttacg gccgcacggt ccgtccggtc agccgaggac gaggctcacg gtgctgacgc
    22861 agttgccggg gggctggatg atgtcgtggt tgttggccgt ctcctggagg tccagaacgg
    22921 agtgcgcctc gacctcgggg gtctcctcgg cgtcgccggc ggcgggcttg gtgttctcgg
    22981 acatggtggt ctccatccac tcgtcacagc ggggccgggt tccgtcgggg atcgcccctc
    23041 ggttgtccgg tgcggcaggc cgttgcctgc cgttgccgag aaagttagga agccgggcct
    23101 ggcgatcgct tcggcggcgg tatggctccg gtatcgggcc agttggcggc gtacggagcc
    23161 cggcccgagg gccccggcgg cggcccgggg acctgccccg acctgggccc ataccgccac
    23221 cgaagcacct tcggaccgtc cgcgaaccgc cgcgccggag cctgggtacg cgcccgacgc
    23281 gcccagcccc gaaggaggcg gcccgcatgg aactcgccga actcgtcgca cggcggccct
    23341 tcccggccgc cggtctgctc ctcggcctca cccggcgctg ccccctgcgc tgcgcgcact
    23401 gctcgaccgg gtcggacctg ttcacccggg aggagccgga cggcggtcaa ctggagcgct
    23461 tcgtcgcctc gttcagcgag gagaaccggc ccgacgtcgt catgctcacc ggcggggaac
    23521 cgctgctgct gcccgcgctc gccgaacggc tgagcacact ggcgcgcagc gccgggtccc
    23581 gtaccgctct gctcagcggc atgttcttcg cccggtccgc gagcaggcgc ggccgaagag
    23641 gcgctgcgat tcctcccgcg atcctgcgcg cgatccgctc cgtcgaccac ttctcggcct
    23701 ccctcgacgt ccaccacgag cgcgaggtcc cgcgcgccga cgtgttccgc gccctgcacc
    23761 ggatccggga cgagggcgtg gccgtgagct tccacctcac cgggaccggc gcgtccgacc
    23821 cgtatctcgc cgacatcacc cgggcggtgg agaaggagtt cggcggccgg gtcccttgcc
    23881 tggtcaacga ggtgcggccg ttcggccggg ccgcctcgtg ggccaggccc gcccgcaccg
    23941 gccccgatcc ggcggcggcg tcgccgtgct cgatggccgc ctggccggtg gtcgccttcg
    24001 acggccgggt gctggcctgc tgcaaccagg acacggtcga ccggcggccc gtaccggccc
    24061 atctggacct cgggcacatc ggcgtcgacg actgggcgac cgtacgccgc cgggcactgg
    24121 agtccccggt gctgcgcatg ctccgcacgg tcgggcccac gcatctggcc gcccggtacg
    24181 gctccggccc cgggacgggc tcctactgcg acggctgccg ggcgctcgac ggcgacgagg
    24241 cggcggcggc cggggcccgt gccgtggcgg gcggggcggc cggagcgctg ctggacctga
    24301 cggccgcggt gcgcggctcc cgggaggggg cgcagggcgt cgtgcgccgc cacggctgcg
    24361 cggcgtacgc gccgctggtc gtcacgggcg ggccgcggct gccggagacc gaagcgcagg
    24421 acctccgatg agcgcgacga ccggcgccgt gtcgctcggc accacggggg cctccgcacg
    24481 tctgcgggtc aaactcctcc tgctggagcc ggagttccgg gacgccaccc accacatgtg
    24541 gcgcgccgaa gggctgttgc cgcgctaccg gacgtatctg tgcaccatgc acaccgtcat
    24601 ccgcgcctcc gtcccgctga tggagctggc cctcgaccgc gcccgcgtcc gggccgcgtc
    24661 cggcgatccg ctggccgcgc cgctcgccgc gtacctggag gagcacatcc gggaggagga
    24721 gggtcatgac gcctggctgc tggaagacct ccgggcggcg ggcggcgacc ccgaggacgc
    24781 gctcggcccg ctgccctctc ccctggtcgc ctcgctcgtc gggccccagt actactggat
    24841 cgagcaccac cacccggtcg ccctgctcgg ctacatcgcc gtactggagg gctacgcgcc
    24901 cgcccccggt ctcaccggcc gtatcgcccg gctgaccgga ctgcccgccg ccgcgctgcg
    24961 gaccgtacgg gagcactcgg tgatcgacac ggagcacctg gacgagctgt acgcgctgct
    25021 ggaccggctg ccgctcggcc gggggccgga agcggccgtg gcggtcagcg cgctgcactc
    25081 cctcgacgcg ctcacccagc tgttcgtccg gctcgggcgc tccgcaccgg cgccgtcgct
    25141 gcggggagcc ggacctgtcc caccgatggg agtcacacca tgaccggacc acccgagaac
    25201 ggccgacggc cggtgctgcc cgacgcgttg tacgaggcgg gtttccccgt cgacctgctc
    25261 accgaggagc agcgcgaggt gctgagcggg ctcaccccgg aggaactggc ggtgctgctg
    25321 gacgtcaagg gccggctgga cgccgtgggg ccggaggtcc aggcgcacgg cgagatcgcc
    25381 ggcggcgccc tgttctgacc ggcggttggt gaccgatcgc cgccagggcc tgtcgtcgca
    25441 ctgccgtcgt cgcccgaagg gcggccggca gacggcnnnn nnnnnngcag acggcagtgc
    25501 gacgacaggc ccttcggtcc cggcgccggg ttcaccgccg ccgggcccgt gcacgccggg
    25561 cccctcgccc ggtgaccccg cccgacaccc cctgaccgca cggcccccgg gagagaagga
    25621 cccgccatga actgctcctc gtgccagcag gatctgccgc cgacggcccg gttctgttcg
    25681 tcctgcggga cgccgtgcgc gaccaccggg cccgccgggg ccggacccgc ccaggccgca
    25741 cccgccggtg acgaacgcaa gccggtgacc gtgctgttct gcgatctcgt cgggtccacc
    25801 gcgctgtcgg gggtgctgga cccggagacg ctgcgcacgg tgaccctgcg ctacttcgag
    25861 gcgatgagcg cggagatcgt ggcacggggc ggcaccccgg agaagttcat cggggacgcg
    25921 gtgatggccg tgttcggcgt accggtggtc cgtgacgacg acgcccgccg ggcgctggcc
    25981 gcggcgctcg ggatgcgccg ggcgctggcc cggctgaacg aggagctgga cgccaccctg
    26041 ggcatcgagc tgaccacccg gatcggtgtc aacaccggtc aggtggtggc gggttcggac
    26101 acgaccgccc ggcaggccct ggtctccggg gagaccgtca acatcgccgc ccggctggag
    26161 cagaacgcgg gccccggcga gatcctgatc ggaccggaaa ccctgctcgc cgccggcccg
    26221 acggtgaggg ccgaacccac cgggccgctg cggctgaagg gcaagcggga cagtgtggag
    26281 gcccaccggc tgctggcgct gggcgccgac gaccccgaac tgctgcgccg cttcgacgtc
    26341 cccttcgtcg gccgcgccac cgaacggcag gcgctggacg ccgccctgga gcgggccgcc
    26401 cgcggcgatc gggccgggct gctgcgggtc accggggagg cgggcatcgg caagacccgg
    26461 ctggtacggg agtggttggc gctgcggtcg gcgtccgggg cgctcgtgta cggcgcggga
    26521 cggtgccgca gttacgggga ccacggcacg ctcgccccgc tggccgacgc ggtgcgttcg
    26581 ctggtggcgg ccgggagcgc gcccacgccc ggacccgggt acgggcatgc gtccggccct
    26641 gcggacgacg cgaaggacgc ggtcggcggt ctcggggtcg acgacacgat ggctctgctg
    26701 tccgggggtc tgctgcgcga cggcacgccg aacgcaccct tcgaggacat gtgcgcggcc
    26761 ctgacggcgg tcctggagcg ggccgccctg gtccgcccgg tcgtcctggt gctggacgac
    26821 tggcacgcgg cggccccgct gctggtccgc acggtgcgca ggctggcgga cggctcgggg
    26881 tgcgcggggg tgctgctgct ctgcgccggg cggccggacg ggccggacga gggggacggg
    26941 cccatcggcg gtgacgagcc catcggtggt gcggggcaac tccagctcac cggcctgccg
    27001 cccgatgagg cggcgcggct ggccgccggt ctcgccggtc cggacggcgg gcccgccccg
    27061 gtggacgacc ggctcctggc gcgggccggg ggcaacccgc tctacctgga acagctcctg
    27121 gtcggcgacc gggcggaccc ggcggccgcc tcccgtccgg gggaacccgt cgccgccgag
    27181 gaggatctgc cgcccacgct ccaggctctg ctgggtgcgc gcatcggggc cctggccagg
    27241 gcggagcgcg gggtggtgga cctggccgcg gtgatcggcc gggagttcac cgcgccggaa
    27301 ctggtccggc tggagctgtc cgtacgggcc ggggagggcc acgacgccgg gcagctcgcc
    27361 ggtgcgaccg gtgcggccgg ggcggccccg gagcaccggc gttacgtcga ggaggcgttg
    27421 gcggtgctgg gccgtcgccg tctggtggag tcggggccgt cggatgaccg ggaggcggcg
    27481 gcgtaccggt tcagcagcgg actggtgcac gaggtcgcgt acgcgtcgct gtccaagcgg
    27541 gccaaggcgg aacgccatgc ctgggcggcg gagctgccca gcgtgctgcg gagcggcgac
    27601 ggcgcggtcg gcggccatct ggagcgcgcc taccgctacc gcgcggagct gggcctgctg
    27661 gacgatccgg cccggcggct gcgcgaacgg gccgccgccg cgctgggccg cgccggggcg
    27721 caggccgccg cccggtccga cctgcactgg gcgcacggcc tgctggagcg ggcggtggac
    27781 ctgtgccccg gggatccggc ggcgacgcgg cggctcggcg aggttcgggt ggcgctgggc
    27841 cacgccgggg agggggccga actgctgcgc cgggtaaggg actcgggggc cgacgcggtg
    27901 gaggccgcgc atgcccgcct cgcgctcgcg gtgctggatc cgggcggccc ggggcccggc
    27961 cccgccgccg tggcccggac cgtgctcccg gtgttcgagg cggccgggga ctcgaccggc
    28021 cgggcgcggg cccatctgcg gctcgcccag cagttccagc ggtccgggcg gcacgaggag
    28081 gcggagcggg accaggcacg ggccctggag cacgcggtgc tggccggtgc ggagccggaa
    28141 cgggccgggg cgctcggcgc gatcggcgtc tccctgtggc gcgggccggt tccggtgccg
    28201 gccgcggtga tccgctgccg ggcgctgctg gcggcgcacg gggcgggctc agcccacggt
    28261 ccgggtcacc ctcaactgcc cgctggcggt gctgtacgcg ctccagagcc ggcccgacga
    28321 ggcgtaccac tgcctggccg aggcggaacg gctggccggg aagctggggt tcgcggaggc
    28381 ggaggtgttc cttccggtgt tccgggcgac ggtggaggcg ctgctcggca acggcgcaac
    28441 ggccctggac ctgctcggcc gggcggacgc ggcggcccgg cgcacgggtg cggccgggat
    28501 gcggacggcg gtggcactgg acgcggcccg gctggagctg gacgcgggcc gggaggaccg
    28561 ggctgccgcc cggctggcgg gcgtcggcga cacatcgggg ctgagccggg cggacgcggt
    28621 ggatctggcg gggctgcggg cccggctggc ggtgcgggac cgcccggagg aggcggcgga
    28681 acacgcggac cgggcggtcc gggcctcgct gctcacagac tccccgctgg tgcaggcgac
    28741 ggccgagctg gaccgggcgc aggcgctcgc cgccctgggc cggtggccgg aggccggggt
    28801 ctcggcccgg tcggccgggg cgcacttcac gggcaagggg catctgccgg gggtgcgccg
    28861 ggtctccggc ttcctcgcga atccgccccg gcccatggcc acgacgaggg agaggagctg
    28921 accgatgacg accacggaac cggaacggac ggggccggga gagccgcggc ctgccccggg
    28981 ggcacgcagg gccccggggc aggggctgac ctggagtctg cgcgggcgcg gcccggagga
    29041 cgtaccggtg ctggcggacc ccgggccacc gctcggccgc ccggcagggc ccgccaccgg
    29101 gcgcggcgta cgggtgtgcg tggtggattc gggtgtggag cgggaccatc cgctgatcgg
    29161 cccgctggcc ggttcctggg tggtcgtcaa ggacgcggag agcggcggga tcacggtcga
    29221 gccgacgacc accggggaca cctgcgggca cggcaccgcg tgcgcgggca tcgtccgccg
    29281 gaccgccccg gagtgcgaga tccacagtgt gcgggtgctc ggggagcggt tctccggcac
    29341 cggcgacgtc ctgatggccg ggctgcgctg ggcggtggag cagggcttcg acgtgatcaa
    29401 cctcagtctg tcgaccaccc gcacccggtt cgcgcaggag ctgcacagcc tggccgacag
    29461 cgcctacttc gcccgtacgg tgatcgtcgc ctcggcccac aacaccccgg tggagagctt
    29521 tccgtggcgg ttcgcctcgg tgatctcggt cggcagccac caggaggacg accccgaact
    29581 gcacctgtac aacccggatc ccccggtgga gttcttcggt cccggccaga acgtgaccgt
    29641 gccgtggctg ggcggccgga cgatccgcac cacggggaac agcttcgcca cgccgtacgt
    29701 cgccgggctc tgcgcccgcg tcctgtccgc gcatccccgg atgacggcct tccagctcaa
    29761 gaacgccctc tatctgtcag cggccaatgt gcgccacgcg ccgcgtcctt ccactgcggc
    29821 aggagatatc cgtgatgact ccgagaactg attccgcccc gtccctctcc cccaccgccg
    29881 ccgccccgga cgccgacgcg ccgcgcagcg agctgctcca gtcggtcgtc gatgtggccc
    29941 gcgccatctt cggggccgag gccagttcgg tcttcctgct cgacgaggag gcggacgagc
    30001 tggtcttcca ggccgtgtcc gggcagggcg aggagttcct cgtgggccgc cggttcccgg
    30061 ccggtcgcgg gatcgccggg tgggtggcga cctccggcga accgatggtg gtggacgacc
    30121 tgagcgccga tccggccttc gaccgctcgc tggccgagtc gaccgcgtac gtgccgaact
    30181 ccctgatggc ggccccgctc atcagcgact cccggatcct cggcgtgctg gaggtactgg
    30241 acccctcccc gcaggcccgg tcgggcgtcc gggagctgga cctgctcgcg atgttcgccc
    30301 ggcaggccgc cgccgccctg cgggtgatca ccccggagcg ggtgcgggag gccgagcagc
    30361 gcgcggcgtc cggcgcgggc gtgctggagg gtgcgcggcg cgaggacgcg ctgaagctgc
    30421 tgggtagcct ggagcgactg ctgcggggaa ccggctgagg aggccggcgt ccgggagtga
    30481 ccaccggccc ggcgggcagg agcggggcga cggcactagg gaaggacacg caccatgaag
    30541 ctcgcattct ccaccctcgg cgtgccggga acgccggtct ccgaggtcgt ccggctcgcg
    30601 gccgggaacg gctaccgggg ggtggagctg cgcgtccacc ccgaggagcc ggtgcacctg
    30661 gggctctcgt cgctggaacg ggccgatgtg gtcgaggagt tcaaggccgg cggggtggag
    30721 atcctggctc tcgccgggta tgtgagggcg gctgccgagg gggacgacga accggtcctg
    30781 gcggagctgt ccgagctggt gaagctggcc cgggacctgg gcgcgtccta cgtccgggtc
    30841 ttccccggcg gcggcgacca ggagcaggcg gaggccgacg cgacggccgc ccggcgactc
    30901 ggagcggccg caccggccgc cgccgacatg ggcgtgagca tcctgctgga gacccatgac
    30961 tcgcaccggg cgggcctcga cgccgcccgg gtcgtcgccg cggtcgggca tccccgggtc
    31021 ggcgcgatct gggacgtgct gcacacctgg ctcgccggtg aggagccggc cgccagccat
    31081 gcggtgctcg ccccgcacct gggatacgtc caggtgaagg acgtcgcatc ggcggacgac
    31141 ctcacgccgg tggcgctggg ctccggggtg gttccgctgg cggactgcct ggacgggctc
    31201 gatccggata cgtgggtgtg ctgggagtac gagaagcgct ggcacccggg ggcacccgag
    31261 ctgccgggtc tgctgggcgc ggggcgcgag cacctgctgc ggctcggggc gccgaagcag
    31321 tagcggcggg gcggtacggg ggcgcggggg ccggtgcgag gcggtgtccc cgc
//
