LOCUS       NZ_CP096281            22214 bp    DNA     linear   CON 08-JUN-2024
DEFINITION  Streptomyces sp. WAC00303 chromosome.
ACCESSION   NZ_CP096281
VERSION     NZ_CP096281.1
KEYWORDS    RefSeq.
SOURCE      Streptomyces sp. WAC00303
  ORGANISM  Streptomyces sp. WAC00303
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1  (bases 1 to 8548838)
  AUTHORS   Meyer,K.J., Tan,S. and Nodwell,J.R.
  TITLE     Genome Sequence of WAC00303 Direct Submission
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 8548838)
  AUTHORS   Meyer,K.J., Tan,S. and Nodwell,J.R.
  TITLE     Direct Submission
  JOURNAL   Submitted (19-APR-2022) Biochemistry, University of Toronto, 1 Kings
            College Circle 5207, Toronto, ON M5S 1A8, Canada
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: 15-MAR-2022
            Assembly Method                   :: Flye v. 2.8.1
            Assembly Name                     :: WAC00303
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 58.0x
            Sequencing Technology :: Oxford Nanopore; Illumina NextSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_023210535.1-RS_2024_06_08
            Annotation Date                   :: 06/08/2024 05:21:48
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 7,823
            CDSs (total)                      :: 7,731
            Genes (coding)                    :: 7,293
            CDSs (with protein)               :: 7,293
            Genes (RNA)                       :: 92
            rRNAs                             :: 6, 6, 6 (5S, 16S, 23S)
            complete rRNAs                    :: 6, 6, 6 (5S, 16S, 23S)
            tRNAs                             :: 71
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 438
            CDSs (without protein)            :: 438
            Pseudo Genes (ambiguous residues) :: 0 of 438
            Pseudo Genes (frameshifted)       :: 228 of 438
            Pseudo Genes (incomplete)         :: 241 of 438
            Pseudo Genes (internal stop)      :: 26 of 438
            Pseudo Genes (multiple problems)  :: 54 of 438
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 18:23:54
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 84768
            Orig. end                         :: 106982
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP096281.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            Bacteria and source DNA available from Justin Nodwell, University
            of Toronto.
FEATURES             Location/Qualifiers
     region          1..22214
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene"
                     /region_number="2"
                     /rules="(PT_phytoene_like or phytoene_synt or Lycopene_cycl
                     or Lycopene_cycl_fung or T1TS or T1TS_KS or T2TS or TS_UbiA
                     or TS_Pyr4)"
                     /tool="antismash"
     cand_cluster    1..22214
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /kind="single"
                     /product="terpene"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..22214
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:12214](+)"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..12214
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
     misc_feature    complement(31..45)
                     /note="TFBS match to VqsM, Regulator of quorum-sensing
                     signalling systems, confidence: medium, score: 18.5"
                     /tool="antismash"
     gene            complement(242..1039)
                     /locus_tag="MWG59_RS00540"
                     /old_locus_tag="MWG59_00540"
     CDS             complement(242..1039)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019766343.1"
                     /locus_tag="MWG59_RS00540"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MWG59_00540"
                     /product="DUF4389 domain-containing protein"
                     /protein_id="WP_097937473.1"
                     /transl_table=11
                     /translation="MAEGQWSPGRKEADADEFRPVLDIVEPARQRRLTVLLRLLLLIPH
                     FIVLFVLHIAAFFTVVVGWFAALVLGRLPDPVFRFLTGVLGYDMRVSASDMLLIDRYPP
                     FALTPPADYPVQIEVRPTPLNRLAVLFRVFLMIPAAIVQSLAVYGWWALAFVWWLITLC
                     LGRMPRPLFEATAATLRYRMRFSAYVMMLTPAYPKGLFGDDDLAVAPERSRSATRPLVL
                     SSAAKWLVVLFLVLGLAGHVISSVTASTTDDIDDTYDTRLVGP"
     assembly_gap    1169..1178
                     /estimated_length=10
                     /gap_type="within scaffold"
                     /linkage_evidence="paired-ends"
     gene            complement(<1179..1828)
                     /locus_tag="MWG59_RS00545"
                     /old_locus_tag="MWG59_00545"
     CDS             complement(<1179..1828)
                     /GO_component="GO:0005576 - extracellular region [Evidence
                     IEA]"
                     /GO_process="GO:0046677 - response to antibiotic [Evidence
                     IEA]"
                     /GO_process="GO:0071555 - cell wall organization [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007458443.1"
                     /locus_tag="MWG59_RS00545"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MWG59_00545"
                     /product="VanZ family protein"
                     /protein_id="WP_248587139.1"
                     /transl_table=11
                     /translation="MLVRGAVLTVVLLGLVAFSVLLAKVTLTPSPASEDLVTANLRPGR
                     SLRQYAEDYTFLAACKQAGGNLLLGVPFGLLLPFFVPRRLRMIRTTLLTAVAMAVVELI
                     QGALVEGRAFDVDDVILNTAGALLGYFVLGRRISHRYYTYTDDSGSPGPSAEKPEVEPK
                     RAPGPAARAKAARTKTAPTKAARAKAAPTRTVRAKTAPTKAARTKTGQRDRSKP"
     gene            1975..2475
                     /locus_tag="MWG59_RS00550"
                     /old_locus_tag="MWG59_00550"
     CDS             1975..2475
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003971171.1"
                     /locus_tag="MWG59_RS00550"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MWG59_00550"
                     /product="tetratricopeptide repeat protein"
                     /protein_id="WP_248583858.1"
                     /transl_table=11
                     /translation="MSAHKKRNLLDEADRLRSEGRPEEARERLLALTAQYPDDAEVAYR
                     TAWIHDVLGLESEAVPYYERALAHPELSSEDRRGALLGLGSTYRILGRYGQAVETLRRG
                     VEEFPDDGSLRAFLAMALYNTDEHHEAMRLLLELTAATSQDPRVQQYRRAMEHYAKDLD
                     ETV"
     gene            2641..3324
                     /locus_tag="MWG59_RS00555"
                     /old_locus_tag="MWG59_00555"
     CDS             2641..3324
                     /GO_component="GO:0005886 - plasma membrane [Evidence IEA]"
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007458446.1"
                     /locus_tag="MWG59_RS00555"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MWG59_00555"
                     /product="YoaK family protein"
                     /protein_id="WP_097935257.1"
                     /transl_table=11
                     /translation="MPWHGEGALLLLSGASGAADAFVFLCVGQVFAGVMTGNLVLLGAS
                     AAGAGEDGVALKVAVALGAYFCGVAAGALLTGRRGPRVRVLLGAEVVLLGAAAALWGLE
                     LVTSYGDRLGVLALVAVAMGVQGRVRVTPTNYFTGTLTSLAGRVALRELRGGDGWVLGR
                     LAAVVAGAALAALAERWWSPGAALGAVVMAAGALVLETVPYRGGRPGPGKGKPRPDRGN
                     PAGAV"
     gene            complement(3548..3808)
                     /locus_tag="MWG59_RS00560"
                     /old_locus_tag="MWG59_00560"
     CDS             complement(3548..3808)
                     /GO_component="GO:0005840 - ribosome [Evidence IEA]"
                     /GO_function="GO:0003735 - structural constituent of
                     ribosome [Evidence IEA]"
                     /GO_process="GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015606682.1"
                     /locus_tag="MWG59_RS00560"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MWG59_00560"
                     /product="type B 50S ribosomal protein L31"
                     /protein_id="WP_248583859.1"
                     /transl_table=11
                     /translation="MKSRIHPVSRPVVFRDRAADAAFLTRSTADSGERVTWEDGNSYPV
                     IDVDTSSASHPFYTGGSQVLDTAGRVEQFRRRYGTGETAGS"
     gene            complement(3873..4037)
                     /gene="rpmG"
                     /locus_tag="MWG59_RS00565"
                     /old_locus_tag="MWG59_00565"
     CDS             complement(3873..4037)
                     /GO_component="GO:0005840 - ribosome [Evidence IEA]"
                     /GO_function="GO:0003735 - structural constituent of
                     ribosome [Evidence IEA]"
                     /GO_process="GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /gene="rpmG"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009192346.1"
                     /locus_tag="MWG59_RS00565"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MWG59_00565"
                     /product="50S ribosomal protein L33"
                     /protein_id="WP_032794160.1"
                     /transl_table=11
                     /translation="MARSETRPVVTLRSTVGTGRSYVTRKNRRNNPDRLELRKFDSAAG
                     RHVLFREVR"
     misc_feature    4081..4096
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: weak, score: 19.65"
                     /tool="antismash"
     misc_feature    4083..4097
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: weak, score: 19.29"
                     /tool="antismash"
     misc_feature    complement(4085..4096)
                     /note="TFBS match to CcpA, Catabolite control protein A,
                     confidence: weak, score: 15.7"
                     /tool="antismash"
     misc_feature    4179..4194
                     /note="TFBS match to LexA_variant_1, Repressor of DNA
                     damage response, confidence: weak, score: 20.2"
                     /tool="antismash"
     gene            4348..5775
                     /locus_tag="MWG59_RS00570"
                     /old_locus_tag="MWG59_00570"
     CDS             4348..5775
                     /GO_function="GO:0016791 - phosphatase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1054: hypothetical
                     protein"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018956434.1"
                     /locus_tag="MWG59_RS00570"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MWG59_00570"
                     /product="SpoIIE family protein phosphatase"
                     /protein_id="WP_248583860.1"
                     /transl_table=11
                     /translation="MPSPLFADRPAPQLPAHDAVDALIHRTRRLRGDVDAVRRDAVMFD
                     EDDPQLRWQRALCELAVQHLDNLDQHLGQLRAGLPDRCADDAPHAVGAPDDPRAGSLLN
                     RVGSAEWNLLTDESSWSEELYEIFGRPPGSTPLSLDDLPSVLLPEDQPVLTAMVTGCLV
                     DGRPMDGEFRIVRPDGRTRTLHMTGEPVLDAEGCTASMWAVLRDVSELRRSEQAVSRNR
                     ASVRREEHIERTEHRMAVELQEAVLPPWRGSLRLPSQGPGALDIAAHYLPSESSGLIGG
                     DWYDAMELPDGRTLLTVGDLTGHGIPATSAMAMMLGALRGMAVAGIEPGALMGHLNQVL
                     ETSIQPALGSALCCRFDPETSILSWAQAGHPAPLLFRHGSGRLLPPPDGMLLGATSNVV
                     FEQDEVRLYPGDVLVLHTDGLTRRGDRGAGPEALFALAPRFADARTAQECVRSVVEEFG
                     GAERLDDACVLVARIGA"
     gene            complement(5827..7317)
                     /locus_tag="MWG59_RS00575"
                     /old_locus_tag="MWG59_00575"
     CDS             complement(5827..7317)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015606686.1"
                     /locus_tag="MWG59_RS00575"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MWG59_00575"
                     /product="hypothetical protein"
                     /protein_id="WP_097935254.1"
                     /transl_table=11
                     /translation="MTGEPNTRLSDLFGLAGWSKGELARMVNRQAAAMGHPQLATDTSR
                     VRRWIDMGESPRDPVPEVLAALFTERLGRVVTIEDLGFGRRGRVGKRRDSGTEHNPDQL
                     PWAPERTAAVLTEFTGMDLMLNRRGLVGAGAALAAGSTIAGPMYDWLHSDPALAADAPR
                     TNDSLHADPAGLDRYEAAPVGSEEIEALEHSVEVFRAWDASRGGGLQRKAVVGQLNEVG
                     GMLAYRHPDHLQRRLWGVAANLAVLAGWMSHDVGLEPTAQKYFVIAAHAAREGGDRPRA
                     GEALSRAARQMVHLGRPDDALDLMKLAKSGSGDETLPRTQAMLRTIEAWAQASMGRGQA
                     MRRTLGEAEELFISDKSDVPAPSWMQMFDEADMHGMQALAFRTLAEHDQGAAIIAQRHA
                     KQALELRVNGRQRSKIFDYISLASACFIANDPDQADRYARLALVSMGETSSHRTWDRLR
                     EMYRLTGQFAGYAGIQDLREEIELSMPPSQKKAKGTQT"
     gene            7549..8685
                     /locus_tag="MWG59_RS00580"
                     /old_locus_tag="MWG59_00580"
     CDS             7549..8685
                     /EC_number="2.7.1.-"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_process="GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) APH"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010060711.1"
                     /locus_tag="MWG59_RS00580"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MWG59_00580"
                     /product="aminoglycoside phosphotransferase family protein"
                     /protein_id="WP_248583861.1"
                     /sec_met_domain="APH (E-value: 2.1e-16, bitscore: 59.4,
                     seeds: 156, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MYTASSSVSAPPRPLRPMGAGGGPYLAPHAGAPVQGPGRARRAAG
                     PGAGPLSGRIDLSGPQGAQVRMAIASVQRICPEFNPVQVLRRSGRSVLIVGTTGRATAV
                     AKCLLDHSPAWTERFRHEIAAYRAFVRHRPPVRAPRLIAADPENCTLVIERMPGRVAAL
                     TRHPVEAPPRADIRAALGAIARVNAWRPPPGLFEAPLDYASRIARYHELGLFTDRDLGD
                     LQKLLHGLAHAGGKQGMGQFCHGDALLSNILLSPTGPVLVDWEHAGWYLPGYDLATLWA
                     VLGDAPVARRQISQLAQARGPAARDAFLVNLMLVLTREIRNYETAVQRTMREAPATGAG
                     ADRPGALSSGEEQRLLLRRLHDDCAMARRAVRAAVGTR"
     misc_feature    7870..7872
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     assembly_gap    8784..8793
                     /estimated_length=10
                     /gap_type="within scaffold"
                     /linkage_evidence="paired-ends"
     gene            9163..9837
                     /locus_tag="MWG59_RS00585"
                     /old_locus_tag="MWG59_00585"
     CDS             9163..9837
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003971163.1"
                     /locus_tag="MWG59_RS00585"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MWG59_00585"
                     /product="transglycosylase SLT domain-containing protein"
                     /protein_id="WP_097935252.1"
                     /transl_table=11
                     /translation="MPRISTLRITRSHKIATAVLVAAGSVSAIAATGGTSEAQTTATRS
                     SISVEPVAAAGIPTAKDAAAKKAAQETAAKEAAAKKAVAARKATAEKDAAEARSEKQAA
                     NRSTERKAVTPKKFANNLDGWIRESLDIMKKKNIPGSYEGLHRNIMRESSGNPNAVNDW
                     DINAQNGIPSKGLLQVIQPTFDAYHVKGTPKKLTDPVANITAAANYAADRYGSIDNVDS
                     AY"
     misc_feature    complement(9885..9899)
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence: weak,
                     score: 17.2"
                     /tool="antismash"
     gene            10001..12214
                     /locus_tag="MWG59_RS00590"
                     /old_locus_tag="MWG59_00590"
     CDS             10001..12214
                     /EC_number="4.2.3.-"
                     /GO_function="GO:0010333 - terpene synthase activity
                     [Evidence IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /GO_process="GO:0046246 - terpene biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: T1TS"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1052: Terpene synthase/cyclase metal-binding domain
                     protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018956438.1"
                     /locus_tag="MWG59_RS00590"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MWG59_00590"
                     /product="terpene synthase family protein"
                     /protein_id="WP_248583862.1"
                     /sec_met_domain="T1TS (E-value: 6.2e-85, bitscore: 285.0,
                     seeds: 237, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAQPFSLPDFYVPYPARLNPHVEAARTHTRAWARSMGMLEGSGIW
                     EEKDLEAHDYALLCAYTHPDCSAEALSLVTDWYVWVFFFDDHFLELFKRTPDREGGKRY
                     LDRLPAFMPMERGAPTPDPENPVEAGLADLWARTVPSMSDAWRARFAEATENLLNESLW
                     ELANIHEGRIANPVEYIEMRRKVGGAPWSAGLVEYAANAEVPDSVADARPLRVLRDAFS
                     DGVHLRNDLFSYQREVEDEGENSNGVLVLEKFLGCSTQEAAEAVNDLLTSRLQQFENTA
                     LTELGPLCAEKSLDPTQTAAVLAYVKGLQDWQSGGHEWHMRSSRYMNGGGAGEAVAGFG
                     MSAASIRFTFRSETSRARSQSHVPYQHVGPSLLPSFDLPFGTTLSPHLEGARVRIVDWA
                     RRMGILEAQPGVPGSNIWDEERLVAIDLPLCAAGLDPDATPDELDLSSGWLAWGTYGDD
                     WFPVVHGRTRDLAGARLANERLSLFMPLDGEGTPEPVNALERSLGDLWRRTAAPMDAGG
                     RRTFRTSIESMTESWLWELANQAQNRIPDPVDYVEMRRATFGSDLTMSLCRLGHGRKVP
                     DEVYRSGPMRSLENAAADYACLMNDLFSYQKEIEYEGEVHNGVLVVQNFFGVDYPTGVA
                     IVHDLMNSRLRQFLHVAEVELPVLYDDFALDAEAREILAGYVQELKHWIAGILIWHRGC
                     RRYREEDLRRGHGTPWHISGPTGLGTSAAQVTRLMAQLAGSPV"
     gene            complement(12291..12848)
                     /locus_tag="MWG59_RS00595"
                     /old_locus_tag="MWG59_00595"
     CDS             complement(12291..12848)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1057: TetR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018956439.1"
                     /locus_tag="MWG59_RS00595"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MWG59_00595"
                     /product="TetR family transcriptional regulator"
                     /protein_id="WP_248583863.1"
                     /transl_table=11
                     /translation="MHAPQTDGRLLKGERRKEELIEATLQVVAREGVAGVSHRAVAREA
                     GLPATAAAYHFTSIDDLLTAALTRCMEQDAQRMLRLAEQADGGPEGVTALAELMEKVVK
                     GPGRLLAEYELYLLAARRPELRGPTRHWLEAISAYGHRYTDDPVRVRVLKGVIDGLLLQ
                     GLLTDTPPTAAEFEAVLRHVLL"
     gene            complement(12904..14163)
                     /locus_tag="MWG59_RS00600"
                     /old_locus_tag="MWG59_00600"
     CDS             complement(12904..14163)
                     /GO_function="GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1020: major
                     facilitator transporter"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007458464.1"
                     /locus_tag="MWG59_RS00600"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MWG59_00600"
                     /product="MFS transporter"
                     /protein_id="WP_097935249.1"
                     /transl_table=11
                     /translation="MANPYGVLFRTPGSRAFTAAGFVARMPLSMAGIGIIAMVSQMRGD
                     YGLAGAVSATFTLSMALCGPRISRAVDRRGQSRVLPPIAGLSVMALGALLLCARYDAPA
                     WTLFGCAAVAGAMPNMAAMVRARWTHALKGSDRLHTAYSLESVVDELTFVVGPALSVAL
                     CTALFPEAGPLVAGVLLVLGVLMFVPQKRTEPPVARPADGHPPTGSAIRSGALRLLALT
                     LVAGGAIVGTVDVVSVSFAEQQGSPAGAGIVLSVYAAGSAVAGLVFGTLRLRTPLPRLL
                     VLGTAGTALTTLPLLLVGDLVTLSAAVFLPGLFFAPTMIVVMGLVERTVPPAVLTEGMT
                     WAITGLSVGVASGAAVSGAIVDRFGPGGGFVVAVAAGATALLTALCARRPLERSLRERA
                     DRDAEGPAEEPAETPGRAAH"
     gene            complement(14378..14878)
                     /locus_tag="MWG59_RS00605"
                     /old_locus_tag="MWG59_00605"
     CDS             complement(14378..14878)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018550733.1"
                     /locus_tag="MWG59_RS00605"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MWG59_00605"
                     /product="hypothetical protein"
                     /protein_id="WP_003971159.1"
                     /transl_table=11
                     /translation="MSFLRRRSAATPAGPDFDVLAMDPGDWPGNLGAGLLPAPDGSCQG
                     VFLRYDLYGGRGPAMIIGNLPEGSPARETEEGQVPFEVAQLLLALENDEPIEVVSSEDV
                     PVMQGDNLLIVRRVKLSESRIACVQFDRSDGVLVTIASWDRPITDDLYTLLKPLPAELF
                     QQG"
     misc_feature    14881..14891
                     /note="TFBS match to HypR, L-hydroxyproline utilization
                     repressor, confidence: weak, score: 18.79"
                     /tool="antismash"
     gene            complement(14955..16121)
                     /locus_tag="MWG59_RS00610"
                     /old_locus_tag="MWG59_00610"
     CDS             complement(14955..16121)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003971158.1"
                     /locus_tag="MWG59_RS00610"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MWG59_00610"
                     /product="thiolase domain-containing protein"
                     /protein_id="WP_248583864.1"
                     /transl_table=11
                     /translation="MSKEPVAVVGIGQTKHVAARHDVSIAGLVREAAVRALEDAGLTWS
                     DIDAVVIGKAPDFFEGVMMPELYLADALGAVGKPMLRVHTAGSVGGSTALVAANLVAAR
                     VHRTVLTLAFEKQSESNAMWGLSLPVPFQQPLLAGAGGFFAPHVRAYMRRTGAPDAVGS
                     LVAYKDRRNALKNPYAHLHDHDITLEKVRAAPMLWDPIRYSETCPSSDGACAMILTDRE
                     GAARSPHPSAWVHGGAMRSEPTLFAGKDFVSPQAGKDCAADVYRQARITDPRREIDAVE
                     MYVPFSWYEPMWLENLGFADEGEGWKLTEAGVTELDGDLPVNPSGGVLSTNPIGASGMI
                     RFAEAALQVRGRAGEHQIDGATRALGHAYGGGAQFFAMWLVGAEPPPG"
     gene            complement(16114..17166)
                     /locus_tag="MWG59_RS00615"
                     /old_locus_tag="MWG59_00615"
     CDS             complement(16114..17166)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018515105.1"
                     /locus_tag="MWG59_RS00615"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MWG59_00615"
                     /product="thiolase domain-containing protein"
                     /protein_id="WP_098013889.1"
                     /transl_table=11
                     /translation="MRDVAIVAFAQTTHRRRTDELSEVDLLMPVLHEVLGATGLKANEI
                     GFTCSGSADYLAGRAFSFTMALDGVGAHPPISESHVEMDGAWALYEAWVKIQTGEADTA
                     LVYSYGKSSPGRVRDVLTRQLDPYYLAPLWPDSVALAALQAQALIDAGATDEGALAEVA
                     ARNRAAAADNPYAQLTGDVPAGDYLVHPLRTGDCPPIGDGAAAVVLAAGDTARALCARP
                     AWIRGIDHRIEAHALGVRDLTDSPSARLAAERAGVFERPVDTAELHAPFTSQEVILRKA
                     LGLGDEVRVNPSGGALAANPVMAAGLIRLGEAAARIHRGESDRALAHATSGPCLQQNLV
                     AVLEGESAHV"
     gene            complement(17167..18114)
                     /locus_tag="MWG59_RS00620"
                     /old_locus_tag="MWG59_00620"
     CDS             complement(17167..18114)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012382254.1"
                     /locus_tag="MWG59_RS00620"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MWG59_00620"
                     /product="OB-fold nucleic acid binding domain-containing
                     protein"
                     /protein_id="WP_248583865.1"
                     /transl_table=11
                     /translation="MSDVLSAPLVVEFPFTRSLGPVQSAFLTGLRERTVLGVRTEDGTV
                     LVPPVEYDPVTANEIRDLVEVAPTGTVTTWAWNPSPGRDQPLGTPFAWVLVRLDGAGTA
                     LLHALDAPGPDAVRTGMRVRIRWAATRTGAITDIACFEPYDGEPGASEPAPHTGEFAEP
                     VTGIVTPARLDYVHTPGRAQSAYLAALEGHRTVGERCPACRKVYVPPRGACPTCGVATA
                     EQVEVGPRGTVTTFCIVNIKAKNLDIEVPYVYAHIALDGADLALHGRIAGIPYDQVRMG
                     LRVEPVWVAGARHPDHYRPSGEPDADYDTYKELV"
     gene            complement(18159..18959)
                     /locus_tag="MWG59_RS00625"
                     /old_locus_tag="MWG59_00625"
     CDS             complement(18159..18959)
                     /NRPS_PKS="Domain: ECH (9-258). E-value: 2.4e-53. Score:
                     172.9. Matches aSDomain:
                     nrpspksdomains_MWG59_RS00625_ECH.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1023: enoyl-CoA hydratase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018956444.1"
                     /locus_tag="MWG59_RS00625"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MWG59_00625"
                     /product="crotonase/enoyl-CoA hydratase family protein"
                     /protein_id="WP_050361615.1"
                     /transl_table=11
                     /translation="MGGTEHLTVRREGATLVLTLNRPQARNALSLPMLVGLYDGWLAAD
                     ADDTVRSVVLTGAGGAFCAGMDLKALAGGGMEGEQYRERMTADPDLHWKAMLRHHRPRK
                     PVIAAVEGPCVAGGTEILQGTDIRIAGAGATFGLFEVRRGLFPIGGSTVRLPRQIPRTH
                     ALEMLLTGRPYTADEAAAIGLIGRVVPDGTALEEALVVAERVNACGPLAVEAVKASVYE
                     GAELTESEALAAELKRGWPVFATEDAKEGARAFAEKRPPVYRRA"
     aSDomain        complement(18186..18932)
                     /aSDomain="ECH"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_MWG59_RS00625_ECH.1"
                     /evalue="2.40E-53"
                     /label="MWG59_RS00625_ECH.1"
                     /locus_tag="MWG59_RS00625"
                     /protein_end="258"
                     /protein_start="9"
                     /score="172.9"
                     /tool="antismash"
                     /translation="RREGATLVLTLNRPQARNALSLPMLVGLYDGWLAADADDTVRSVV
                     LTGAGGAFCAGMDLKALAGGGMEGEQYRERMTADPDLHWKAMLRHHRPRKPVIAAVEGP
                     CVAGGTEILQGTDIRIAGAGATFGLFEVRRGLFPIGGSTVRLPRQIPRTHALEMLLTGR
                     PYTADEAAAIGLIGRVVPDGTALEEALVVAERVNACGPLAVEAVKASVYEGAELTESEA
                     LAAELKRGWPVFATEDAKEGARAFAEK"
     misc_feature    19013..19028
                     /note="TFBS match to ColR, Phenol-responsive regulator,
                     confidence: weak, score: 17.75"
                     /tool="antismash"
     misc_feature    19014..19030
                     /note="TFBS match to HexR, Glucose-responsive regulator,
                     confidence: weak, score: 16.71"
                     /tool="antismash"
     misc_feature    19018..19032
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence: weak,
                     score: 16.75"
                     /tool="antismash"
     misc_feature    complement(19035..19048)
                     /note="TFBS match to CatR, H2O2-responsive repressor,
                     confidence: weak, score: 17.99"
                     /tool="antismash"
     gene            19126..20748
                     /locus_tag="MWG59_RS00630"
                     /old_locus_tag="MWG59_00630"
     CDS             19126..20748
                     /NRPS_PKS="Domain: AMP-binding (8-438). E-value: 2.8e-65.
                     Score: 212.4. Matches aSDomain:
                     nrpspksdomains_MWG59_RS00630_AMP-binding.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) AMP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1002: AMP-dependent synthetase and ligase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007458480.1"
                     /locus_tag="MWG59_RS00630"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MWG59_00630"
                     /product="acyl-CoA synthetase"
                     /protein_id="WP_248583866.1"
                     /sec_met_domain="AMP-binding (E-value: 7.5e-69, bitscore:
                     231.1, seeds: 400, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEYNLADLFESVVDAVSDREALLYVDHPGTGAERRLTYAELDAAA
                     NRIAHHLIDAGIRPGEHLGLHLYNGVEYLQTVLGALKARIVPVNVNYRYVEEELVYLYR
                     DADLAALVFDGEFDERVATAAPQAPGLRHLVRVGPAPAAPPAVPVVPFTEAERSGGSGR
                     GFAPRSADDQFIIYTGGTTGMPKGVMWRQEDLFFSGLGGGAPTGEPVKAPQELAERVAA
                     GGDGITFFPTPPLMHGTSTLTAFIGFNFGQRVVVHRKFVPAEVLRTIEKEKVTSVSLVG
                     DAMLRPLIDCLNGPLRGTDCSSLFSVSSSGAIMSDSVRAEFQALVPTVMLLNNFGSSES
                     GFNGTATADSGPERGFRVQVNARTAVVDPVTYEPVAPGEPGRIAQRGHVPLGYYNDPAK
                     TADTFFRRGEERWVLLGDMATVDADGIVTVLGRGSQCINTGGEKVYPEEVEQALKSHPD
                     VYDALVAGVPDERWGNRVAAVVQLRQNIEALTLEAVQAHCRTRLAGYKIPRALVLADRI
                     QRSPSGKADYRWAKAVAAGADQG"
     aSDomain        19150..20439
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_MWG59_RS00630_AMP-binding.1"
                     /evalue="2.80E-65"
                     /label="MWG59_RS00630_AMP-binding.1"
                     /locus_tag="MWG59_RS00630"
                     /protein_end="438"
                     /protein_start="8"
                     /score="212.4"
                     /specificity="substrate consensus: X"
                     /tool="antismash"
                     /translation="FESVVDAVSDREALLYVDHPGTGAERRLTYAELDAAANRIAHHLI
                     DAGIRPGEHLGLHLYNGVEYLQTVLGALKARIVPVNVNYRYVEEELVYLYRDADLAALV
                     FDGEFDERVATAAPQAPGLRHLVRVGPAPAAPPAVPVVPFTEAERSGGSGRGFAPRSAD
                     DQFIIYTGGTTGMPKGVMWRQEDLFFSGLGGGAPTGEPVKAPQELAERVAAGGDGITFF
                     PTPPLMHGTSTLTAFIGFNFGQRVVVHRKFVPAEVLRTIEKEKVTSVSLVGDAMLRPLI
                     DCLNGPLRGTDCSSLFSVSSSGAIMSDSVRAEFQALVPTVMLLNNFGSSESGFNGTATA
                     DSGPERGFRVQVNARTAVVDPVTYEPVAPGEPGRIAQRGHVPLGYYNDPAKTADTFFRR
                     GEERWVLLGDMATVDADGIVTVLGRGSQCIN"
     CDS_motif       19645..19695
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_MWG59_RS00630_0001"
                     /evalue="3.00E-06"
                     /label="NRPS-A_a3"
                     /locus_tag="MWG59_RS00630"
                     /protein_end="190"
                     /protein_start="173"
                     /score="19.8"
                     /tool="antismash"
                     /translation="FIIYTGGTTGMPKGVMW"
     CDS_motif       20290..20337
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_MWG59_RS00630_0002"
                     /evalue="3.70E-04"
                     /label="NRPS-A_a6"
                     /locus_tag="MWG59_RS00630"
                     /protein_end="404"
                     /protein_start="388"
                     /score="13.0"
                     /tool="antismash"
                     /translation="VPLGYYNDPAKTADTF"
     misc_feature    complement(20805..20816)
                     /note="TFBS match to CcpA, Catabolite control protein A,
                     confidence: medium, score: 16.94"
                     /tool="antismash"
     gene            20838..21146
                     /locus_tag="MWG59_RS00635"
                     /old_locus_tag="MWG59_00635"
     CDS             20838..21146
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005322088.1"
                     /locus_tag="MWG59_RS00635"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MWG59_00635"
                     /product="PadR family transcriptional regulator"
                     /protein_id="WP_097934254.1"
                     /transl_table=11
                     /translation="MREFQRGAVRLHILHHAAEEEIHGAWMTEELASHGYRISPGTLYP
                     TLHRLEADGLLVSEQRVVDGRTRRVYWATEAGKKALDEDRRALRELAREVLGGDGAP"
ORIGIN
        1 aggtgatcct cgacgcgccg gcctccgcgg tggccggcca catccgcgac gggagcgtcg
       61 aggagtacgg cccggaccgc tgccgcgtgg tcctgggcgc ctggtcctgg gccggcctcg
      121 ccgccgaact cggcaggttc gacgtggaca tcgaggtcgt cgggcccgac gggctcaggg
      181 atgccttcgc ccggttggcc cgccgctttg ccgccgctgc gggggcgggg cccggcggct
      241 ctcagggacc gacgagccgc gtgtcgtagg tgtcgtcgat gtcgtcggtc gtcgatgcgg
      301 tcacggacga gatgacgtga cccgccaggc ccagcaccag gaacagcacc acgagccatt
      361 tcgcggcgct gctcaggacc agcgggcggg tggcggaacg cgaccgctcc ggggccacgg
      421 cgaggtcgtc gtcgccgaac aggcccttgg ggtaggcggg ggtgagcatc atgacgtacg
      481 cggagaaccg catccggtag cgcagggtgg ccgccgtcgc ctcgaacagc ggccggggca
      541 tccggccgag acacagcgtg atcagccacc agacgaaggc cagcgcccac cacccgtaca
      601 cggcgagact ctgcacgatc gccgccggga tcatcaggaa gacgcggaac agcaccgcga
      661 gccggttgag cggggtgggc cgcacctcga tctgcaccgg atagtcggcc ggcggggtca
      721 gggcgaaggg cgggtagcgg tcgatgagca gcatgtcgct cgccgagacg cgcatgtcgt
      781 agccgaggac gccggtcagg aagcggaaga cggggtcggg cagccgtccc agcaccagcg
      841 ccgcgaacca tcccacgaca acggtgaaga acgccgcgat gtgcaggacg aacagcacga
      901 tgaagtgcgg gatcagcagc aggagtcgca ggaggacggt cagccggcgc tgacgggccg
      961 gttcgacgat gtccaggacg ggcctgaact cgtccgcgtc cgcctccttg cggcccgggc
     1021 tccactggcc ttcggccatg tcgctcctcc tcggcagggg atccgggcgc catccgcgcg
     1081 caggacgtgt ccccaccgtg cgtccgctcc gggccgcccg caaacggccc ggcccgaacg
     1141 ggtgcccctg ctcagcgccc gcggaggcnn nnnnnnnngg cttcgaccgg tcccgttgtc
     1201 cggtcttcgt acgggcggcc ttcgtagggg cggttttggc acggaccgtc ctagtagggg
     1261 cggccttggc gcgggccgcc ttcgtaggag cggtctttgt acgggccgcc ttggcacggg
     1321 cggccggccc cggcgcacgc ttcggctcga cctcgggctt ctccgccgac gggccggggg
     1381 agcctgagtc gtcggtgtag gtgtagtagc ggtggctgat ccggcggccc agcacgaagt
     1441 accccagcag cgcgcccgcc gtgttgagga tgacgtcgtc gacgtcgaag gcgcgcccct
     1501 cgaccagggc cccctggatc agttcgacga cggccatggc gacggcggtc agcagcgtcg
     1561 tccggatcat gcgcaggcgg cgtggcacga agaacggcag caggagtccg aacggcacgc
     1621 cgagcagcag gttcccgccc gcctgcttgc acgcggcgag gaaggtgtag tcctcggcgt
     1681 actggcgcag cgagcggccg gggcggagat tcgcggtgac gaggtcctcg gatgccggtg
     1741 acggcgtgag cgtcaccttg gccaggagga cggagaacgc cacgagtccc agcagcacca
     1801 ccgtcaggac cgccccgcgc accagcacac gtacccatgt cccccggtct gtacggggat
     1861 tcgcctctgc tgtcatggcc gacgggtgcc cgcccggccg gaacacacac ctggacggcc
     1921 ccgtggagcg aaaatctcat gttgccgtcc gcacccgcct gcgacgatgt gcgcatgagc
     1981 gcacacaaga agaggaacct gctggacgag gccgaccggt tgcgttcgga gggccggccc
     2041 gaggaggctc gcgaacggct cctcgccctg accgcccagt accccgacga cgcggaggtg
     2101 gcctaccgga cggcgtggat ccatgacgtg ctgggcctgg agtcggaggc cgtgccgtac
     2161 tacgagcgcg ctctggcgca tccggaactc tcttcggagg accggcgggg ggcgctcctg
     2221 gggctgggca gtacgtaccg gatcctcggg cggtacgggc aggcggtgga gacgctgcgc
     2281 cgaggcgtcg aggagttccc ggacgacggt tcgctccggg cgttcctggc gatggcgctg
     2341 tacaacaccg acgagcacca cgaggcgatg cgcctgttgc tggagttgac ggccgcgacc
     2401 agccaggacc cgcgcgtcca gcagtaccga cgggcgatgg agcactatgc gaaggacctc
     2461 gacgagaccg tgtgacccgt gcgggccggg gcggtcgccc gcggcgcgcc gtatcgcggc
     2521 ggacgcgccg gtccgggagc ggtggatgcc gagaatgctc gggtgcccac cgctcccccg
     2581 gcgcccccgc cgcccccgtc tccctctccc tcctcctccg gcgcctcccg ggccggtgat
     2641 gtgccgtggc acggcgaggg ggcgctgctt ctgctgtccg gggcctccgg cgcggcggac
     2701 gcgttcgtct tcctgtgtgt ggggcaggtc ttcgccgggg tgatgacggg gaacctggtg
     2761 ctgctcgggg cttcggccgc cggtgcgggc gaggacggcg tggcgctgaa ggtggctgtc
     2821 gctctggggg cgtacttctg cggggtggcg gcgggcgcgc tgttgaccgg gcggcgaggt
     2881 ccccgggtcc gggtgctgct gggggcggag gtcgtcctgc tgggggcggc ggccgcgctg
     2941 tgggggctgg agctggtcac gtcgtacggc gaccggctcg gggtgctggc tctggtggcg
     3001 gtcgcgatgg gcgttcaggg gcgcgtccgg gtgacgccga cgaactattt caccgggacg
     3061 ctgacctcgc tcgcgggtcg cgtggcgctg cgggagctgc gcggcgggga cggctgggtg
     3121 ctggggcggc tggccgcggt ggtggccggg gcggcgctcg cggcactggc cgagcggtgg
     3181 tggagtccgg gggccgcgct gggcgcggtg gtgatggccg cgggtgctct ggtgctggag
     3241 acggtcccgt accggggcgg ccggccgggg ccgggcaagg ggaagccccg gccggatcgg
     3301 gggaatccag ccggggcggt ctgagtgcgg gcgtgaaggg cggtcgcctc tcggcggagg
     3361 gctccacggg gcttcggcgg tgcgatcttc cccatgggct acaggtgagg cccggggacg
     3421 ctgtccccct cactcccacg tatagatgaa cgataaacca tcctgggccg ttcccgggaa
     3481 tccgcccccg cggatgtgat ccacggcacg gagtcccggg cttcctccct ggtcaggact
     3541 cgctcggtca gctcccggcc gtctcgccgg tgccgtaacg gcgccggaac tgttcgacgc
     3601 ggcccgccgt gtcgagcacc tggctgccgc cggtgtagaa cgggtggctc gccgacgagg
     3661 tgtccacatc gatgacgggg tagctgttgc cgtcctccca cgtcacacgc tcgccggagt
     3721 cggcggtcga gcgggtcagg aaggcggcgt cggccgcgcg gtcgcggaag accacgggac
     3781 gggacacggg gtggattcgg gacttcatcg atgcgttcct tcctcaccgc gggcagcggt
     3841 gacgtacatg gggacaggtc tcttccgggc ggtcagcgga cctcgcggaa caggacgtgc
     3901 cggccggcgg cggagtcgaa cttgcggagc tccagccggt cggggttgtt gcggcggttc
     3961 ttgcgtgtca cataactccg gcccgttccg acggtggacc ggagggtgac gaccggcctg
     4021 gtctcgctgc gtgccatggg cgcctcccga tgcctctgcc gaccccgctc ccgtatcggg
     4081 aatgggattc gttttcgttc tggtgaggta acgcgagccg ccccctcggc attcccgccc
     4141 cacaacgcac cccgaatcgc agagtcaact cgccccaaac gtaagcctgt tcggataccc
     4201 accgccccgg agagccgctg gcacatgcca gacgcaagaa cgcatcgagt gttgccaaat
     4261 cccttacgac ctgccgtggc ctgtgcgaca gtcggtagcg gtccaccctt cagaaccggc
     4321 taggccgcgc ctgtatcgga gtacgagatg ccgtcccccc tcttcgcgga ccgccccgca
     4381 ccacagcttc ccgcgcatga cgccgtcgac gccctgatcc accggacgcg tcggctgcgc
     4441 ggggatgtgg acgccgtgcg gcgggacgcg gtcatgttcg acgaggacga cccccagctg
     4501 cgttggcagc gcgccctgtg cgagctggcg gtgcagcacc tggacaacct cgaccagcac
     4561 ctgggccagc tccgggcggg tctgccggac cggtgcgccg acgacgcccc ccatgctgtc
     4621 ggggccccgg acgacccgag ggccggttcc ctgctgaacc gggtgggcag cgccgagtgg
     4681 aacctcctca ccgacgagtc cagctggtcc gaggagctgt acgagatctt cggcaggccg
     4741 cccgggtcca cacccctctc cctcgacgac ctgccgtccg tgctgctgcc cgaggaccag
     4801 ccggtgctga ccgccatggt gacgggctgc ctcgtcgacg gccggccgat ggacggcgag
     4861 ttccgcatcg tgcgtcccga cggccgcacg cgcaccctgc acatgacggg cgagccggtc
     4921 ctcgacgccg agggctgcac cgcctccatg tgggcggtcc tgcgggacgt cagcgagctg
     4981 cggcgcagcg agcaggccgt gagcagaaac cgcgcgtcgg tacggcgcga ggagcacatc
     5041 gagcgcaccg agcaccgcat ggccgtggag ctccaggaag ccgtccttcc cccgtggcgc
     5101 ggatcgctgc ggctcccgtc acagggcccc ggcgccctgg acatcgccgc gcactacctc
     5161 ccttccgagt cgagcggcct catcggcggc gactggtacg acgcgatgga actgccggac
     5221 gggcgcaccc tgctcaccgt cggcgacctc accgggcacg gcattcccgc cacctcggcg
     5281 atggcgatga tgctgggcgc actgcgcggc atggcagtcg ccggcatcga gccgggcgcg
     5341 ctgatgggac acctcaacca ggtgctcgaa acgtcgatac agcccgcgct gggcagcgcc
     5401 ctgtgctgcc gcttcgaccc cgaaacctcc atcctgtcct gggcgcaggc cggacacccc
     5461 gcaccgctgc tcttccgcca cggttcgggg cggctgctgc ccccgccgga cgggatgctg
     5521 ctcggcgcca cgtccaacgt ggtcttcgag caggacgagg tacggctgta ccccggtgac
     5581 gtgctcgttc tgcacaccga cggcctgacc cgacgcggcg accggggtgc gggcccggag
     5641 gcgctgttcg ccctcgcccc ccggttcgcg gacgcccgta cggcacagga gtgcgtacgg
     5701 agcgtcgtcg aggagttcgg cggggccgag cgcctggacg acgcgtgcgt gctggtcgcc
     5761 cgcatcgggg catgaggaag cgcggacgta tcagggcgtg acggagcgcg gagcggcgct
     5821 gccgggtcag gtctgcgtgc ccttggcctt cttctggctc ggcggcatcg agagctcgat
     5881 ctcctcgcgc aggtcctgga tccccgcgta tccggcgaac tgcccggtga gccggtacat
     5941 ttcgcggagc cggtcccagg tgcggtgcga ggaggtctcc cccatcgaca ccagcgcgag
     6001 ccgggcgtac cggtcggcct gatcggggtc gttggcgatg aagcaggccg aggccagcga
     6061 gatgtagtcg aagatcttcg accgctggcg cccgttgacc cgcagctcca gcgcctgctt
     6121 ggcatggcgc tgggcgatga tcgcggcgcc ctggtcgtgc tcggccaggg tccggaaggc
     6181 cagcgcctgc atgccgtgca tatcggcctc gtcgaacatc tgcatccaac tgggcgccgg
     6241 aacatcgctc ttgtccgaga tgaagagctc ctcggcctcg ccgagggtgc gccgcatggc
     6301 ctgcccccgg cccatcgacg cctgtgccca ggcctcgatg gtgcgcagca tcgcctgcgt
     6361 acgcggcagg gtctcgtcgc cggagccgga cttggcgagc ttcatcaggt cgagtgcgtc
     6421 gtcggggcgg cccaggtgca ccatctggcg tgccgcccgg gagagcgcct ctccggcgcg
     6481 cggccggtcg ccgccctcgc gggccgcgtg ggcggcgatg acgaagtact tctgggcggt
     6541 gggttcgagg ccgacgtcgt gggacatcca gcccgccagg acggcgaggt tggcggcgac
     6601 gccccacagg cggcgctgga gatggtctgg gtggcggtag gcgagcatgc cgcccacctc
     6661 gttgagctgg cccacgaccg ccttgcgctg gagtccgccg ccccgggacg cgtcccaggc
     6721 gcggaacacc tcgaccgaat gctccagggc ctcgatctcc tcggagccga ccggcgccgc
     6781 ctcgtaccgg tcgagaccgg ctggatcggc gtgcagggaa tcgttggtac gtggagcgtc
     6841 ggccgccaga gcggggtcgc tgtgcagcca gtcgtacatg gggccggcga tggttgagcc
     6901 ggcggcgagc gcggcgcccg cacccaccaa gccgcgtcgg ttgagcatga ggtccattcc
     6961 cgtgaattcg gtgaggaccg ctgccgtccg ttcgggcgcc cacggcaatt gatcgggatt
     7021 gtgttccgtc ccggagtcac gccgcttccc cacacgcccg cgtcggccga acccgaggtc
     7081 ctcgatggtc acgacacggc cgagacgctc ggtgaacaga gccgccagca cttcgggcac
     7141 gggatcacgg ggggattccc ccatgtcgat ccagcgcctg acgcgcgagg tgtcggtggc
     7201 cagctgcggg tggcccatgg ccgccgcctg ccggttcacc attctcgcga gttcgccctt
     7261 ggaccagccg gccaggccga acaggtcaga aaggcgggtg ttgggttctc cggtcactac
     7321 aagcccccag gttctcggct gacttgacac taaccccctg tcagatgcgc tgtgactatt
     7381 cgccagggtt cgccagggtc cgccagatgg tctgccaccc gcgctccggt gtcaggtagg
     7441 aaagcgccac cccgcccggc agccctaggt actccccagg gtgccgaacg gccgtcggcc
     7501 gggttggcgc acgtaacttg tcggcgcacg aagggatctg tctcgcccat gtacacagca
     7561 tcgtcctccg tgtccgcccc gccccgtccg ctccgcccga tgggcgcggg cggcgggccc
     7621 tatctcgctc ctcacgccgg cgcaccggtg cagggtccgg gccgggcccg acgggccgcg
     7681 ggaccgggcg ccggaccgct cagcggaagg atcgacctgt ccgggcccca gggcgcgcag
     7741 gtgcggatgg ccatcgcctc cgtgcagcgc atctgccccg agttcaaccc ggtccaggta
     7801 ctgcgccgca gcggccgttc ggtcctgatc gtcggaacga ccgggcgggc caccgccgtc
     7861 gcgaagtgtt tactggacca ctcgccggcg tggaccgaac ggttccggca cgaaatagcg
     7921 gcgtaccgcg cgttcgtccg gcaccgcccc cctgttcggg cgccccggct gatcgcggcg
     7981 gatccggaga actgcacgct ggtgatcgag cggatgcccg gccgggtcgc cgccctcacc
     8041 cggcacccgg tggaggcgcc gccgcgggcc gacatccggg ccgcgctcgg agccatcgcc
     8101 cgggtgaacg cctggcgacc gccgcccgga ctgttcgagg ctccgctcga ttacgcgtcg
     8161 cggatcgcgc gctaccacga gctcggtctg ttcaccgacc gtgacctcgg tgacctgcag
     8221 aagctcctgc acggtctggc ccacgcgggc ggcaagcagg gcatggggca gttctgccac
     8281 ggggacgccc tgctctccaa catcctgctg tcgccgaccg gaccggtgct cgtcgactgg
     8341 gagcacgccg ggtggtatct cccggggtac gacctggcga cgctgtgggc ggtgctgggc
     8401 gacgccccgg tggcgcgacg ccagatcagc cagctcgccc aggcgagggg gccggccgca
     8461 cgggacgcgt tcctggtgaa cctgatgctg gtgctgaccc gcgagatccg caattacgag
     8521 acggcggtcc agcgcacgat gcgcgaggcg cccgcgacgg gggcgggggc cgaccggccc
     8581 ggcgctctct cctcgggcga ggagcagcga ctgctgctgc ggaggctgca cgacgactgc
     8641 gccatggcgc ggcgggcggt gcgggccgcg gtcggtaccc gctgagaccg gacgacggag
     8701 cggggatacg ccccgcctgc cgagaaccac agtgaccaga ccactgtgaa gaagaagcgg
     8761 gggggggggg gggggggggg gggnnnnnnn nnncagcgcg ctgttgtgcg ttccgggccg
     8821 tatctccccg tgaccgcgcg ttgaccctgt gccgccccgg ggtcgcccgc gggtgaggcc
     8881 cgccacgaga cccacgtcac ctacgacctg cggtagtagg cgcgagccct cccggacggc
     8941 gtaacgaacc gcccatatgg ctcataaatt ggcatctcac gatgaagagt agtaaaggcg
     9001 gtcattgctt cctatgtcgg cgagcgctaa ccatggatcc cggcaggcac cgagttcgag
     9061 cccgcgtcga tcgccctccg gcgaccgcgg cccggaccat ccggttcccg ccgacgcggc
     9121 gcgaaggccg cgaagcccgt cccccatagg aagagctcac gcatgccccg catctccacc
     9181 ctgcgcatca cccgctcgca caagatcgcc accgccgtgc tcgtcgcggc cggttccgtc
     9241 agcgccatag ccgccaccgg cggcacgagc gaagcgcaga ccacggcgac ccggtcctcc
     9301 atctccgtgg agccggtcgc cgccgcaggc atccccacgg cgaaggacgc ggcggccaag
     9361 aaggccgctc aggagaccgc cgccaaggaa gccgccgcga agaaggccgt ggccgcccgc
     9421 aaggccaccg cggagaagga cgccgcagag gcgcgctccg agaagcaggc cgccaaccgc
     9481 tccaccgagc gcaaggcggt cacgcccaag aagttcgcga acaacctcga cggctggatc
     9541 cgcgagtcgc tcgacatcat gaagaagaag aacatccccg gctcctacga ggggctgcac
     9601 cgcaacatca tgcgcgagtc cagcggcaac ccgaacgcgg tcaacgactg ggacatcaac
     9661 gcgcagaacg gcattccctc caaggggctc ctccaggtga tccagcccac cttcgacgcc
     9721 taccacgtca agggcacccc gaagaagctc accgacccgg tcgccaacat caccgccgcc
     9781 gccaactacg ccgcggaccg gtacggctcg atcgacaacg tcgactccgc ctactgagcg
     9841 accgacttcc gaacgaccgc cttccgagcg cgcaccaacg ccgcgattat gtgactaatc
     9901 gccgccgtgc gtgctccgta tggccgaagg gtagtgctgc gcggacacca tcggtccgcg
     9961 cgtttccccg cgcggaggct tctggaaagg cccgacgcac atggcacagc ccttctcact
    10021 gccggacttc tatgttccgt atccggcgcg gctcaaccct catgtggagg cggcacgcac
    10081 gcacacccgc gcgtgggccc gctccatggg gatgctggag ggatccggca tctgggagga
    10141 gaaggacctg gaggcgcacg actacgccct cctgtgcgcc tacacccacc ccgactgctc
    10201 ggccgaggca ctctccctgg tcaccgactg gtacgtgtgg gtcttcttct tcgacgacca
    10261 cttcctggaa ctgttcaagc gcacgcccga ccgggagggc ggcaagcggt atctggaccg
    10321 cctgccggcc ttcatgccga tggagcgcgg cgccccgacg ccggatccgg agaacccggt
    10381 cgaggcgggg ctcgccgatc tgtgggcgcg cacggtcccc tcgatgtcgg acgcctggcg
    10441 ggcccggttc gcggaggcga cggagaacct cctcaacgag tccctgtggg agctcgccaa
    10501 tatccacgag ggccgcatcg ccaaccccgt cgagtacatc gagatgcgcc gcaaggtggg
    10561 cggcgcgccc tggtccgcgg gtctggtgga gtacgcggcg aacgccgagg tgcccgattc
    10621 ggttgccgac gcccgcccgc tgcgggtgct ccgggacgcg ttctccgacg gggtgcatct
    10681 gcgcaacgac ctcttctcct accagcgtga ggtggaggac gagggggaga acagcaacgg
    10741 cgtactggtg ctggagaagt tcctcggctg ctccacgcag gaggccgccg aggcggtcaa
    10801 cgacctgctg acctcacggc tccagcagtt cgagaacacc gcgctgaccg aactcggccc
    10861 gctctgcgcc gagaagagcc tggacccgac gcagaccgcc gccgtgctgg cgtacgtcaa
    10921 ggggctccag gactggcagt ccggcggcca cgaatggcac atgcgctcca gccgctacat
    10981 gaacggcggc ggcgcgggcg aggccgtggc cggcttcggc atgtccgccg cctccatcag
    11041 gttcacgttc cgctcggaga cctcgcgggc ccgaagccag agccatgtcc cgtaccagca
    11101 cgtgggcccc tcgctgctgc cgagcttcga cctgccgttc gggacgacgc tgagcccgca
    11161 tctggagggg gcgcgggtcc ggatcgtcga ctgggcgcgg cggatgggca tcctggaggc
    11221 gcagccgggt gtgcctggtt cgaacatctg ggacgaggaa cggctcgtcg cgatcgacct
    11281 gccgctgtgc gcggcgggcc tggatccgga cgcgaccccg gacgagctgg acctgtcctc
    11341 ggggtggctg gcctggggga cgtacgggga cgactggttc ccggtcgtgc acgggcggac
    11401 ccgggacctg gcgggggcgc ggctggccaa cgagcggctc tcgctgttca tgccgctgga
    11461 cggcgagggg acgccggagc cggtgaacgc cctggagcgg agcctgggcg acctgtggcg
    11521 caggacggcc gcaccgatgg acgcgggcgg ccggcgtacc ttccggacct cgatcgagtc
    11581 catgaccgag agttggctgt gggagctggc gaaccaggcg cagaaccgta tccccgaccc
    11641 ggtggactac gtggagatgc ggcgggcgac gttcggttcg gacctgacga tgagcctgtg
    11701 ccggctcggg cacggcagga aggtcccgga cgaggtctac cgcagcggtc cgatgcgttc
    11761 cctggagaac gcggcggcgg actacgcgtg cctgatgaac gatctgttct cgtaccagaa
    11821 ggagatcgag tacgagggcg aggtccacaa cggcgtcctg gtcgtgcaga acttcttcgg
    11881 cgtcgactat ccgacgggcg tggcgatcgt gcacgacctg atgaactcgc ggctgcggca
    11941 gttcctgcat gttgccgagg tcgaactccc ggtgctgtac gacgacttcg ccctggacgc
    12001 cgaggcgcgg gagatcctgg cgggatatgt gcaggagctc aagcactgga tcgcggggat
    12061 tctgatctgg caccggggct gccggcgcta ccgtgaggag gacctgcggc gcggccacgg
    12121 cacgccctgg cacatcagcg gccccacggg cctcggcacg tcggcggcgc aggtgacccg
    12181 gttgatggcc caactggcgg gaagcccggt gtagttcgcg gggtcgcggc ccgtcgtccg
    12241 gaggaactgc acggcgggcc gcgaccggtg gcggaccggc cgggcagtgc tcagagcagt
    12301 acgtgccgga gcaccgcctc gaactccgcc gccgtcggcg gggtgtcggt cagcagcccc
    12361 tggagcagca ggccgtcgat gacgcccttg agcacccgca cccggaccgg gtcgtcggtg
    12421 tagcggtggc cgtacgccga gatggcctcc agccagtgcc gggtggggcc gcgcagctcc
    12481 gggcggcggg ccgcgagcag gtacagctcg tactccgcga gcagccgtcc gggacccttg
    12541 acgaccttct ccatcagctc cgccagcgcg gtgacgccct cggggccgcc gtcggcctgc
    12601 tcggccagcc ggagcatgcg ttgcgcgtcc tgttccatgc agcgggtgag cgcggcggtg
    12661 agcaggtcgt cgatgctcgt gaagtggtag gcggcggcgg tggcgggcag gcccgcctcg
    12721 cgggcgaccg cccggtggct gacgccggcg actccttccc gggcgaccac ctggagcgtg
    12781 gcctcgatga gttcctcctt ccgtcgctcg cccttgagca gacgtccgtc ggtctgtggt
    12841 gcgtgcacgg tgcctccggg cgtcgtggtg ggtggggcgg cgggtgcgct tcggcgccgt
    12901 ccgtcagtgt gcggcccttc cgggggtctc ggccggttcc tcggccggtc cctcggcgtc
    12961 gcggtccgcc cgctcccgga gactccgctc cagcggacgc cgggcgcaca atgctgtcag
    13021 cagagcggtc gcgcccgcgg ctacggcgac gacgaagccg ccgccggggc cgaagcggtc
    13081 gacgatcgct cccgacaccg cggcgccgga cgcgacgccc acgctgaggc cggtgatggc
    13141 ccaggtcatg ccctcggtga gtacggcggg cggcaccgtc ctctccacca gccccatcac
    13201 cacgatcatg gtaggcgcga agaagagtcc cgggaggaag acggcggcgg acagcgtgac
    13261 gaggtccccg acgagcagca gggggagggt cgtgagcgcc gttccggcgg tgccgaggac
    13321 gagcagccgg ggcagcggtg tcctgagcct gagcgtcccg aagaccagac cggcgacggc
    13381 ggatccggcc gcgtagaccg agaggacgat tcccgcaccg gcgggtgatc cctgctgttc
    13441 ggcgaacgag acgctcacga cgtcgacggt gccgacgatg gcgccgccgg ccacgagcgt
    13501 gagggccagc aggcggagcg ctccgctgcg gatcgccgag ccggtgggcg ggtgcccgtc
    13561 ggccggccgg gccaccggag gttcggtgcg cttctgcggg acgaacatga ggacgccgag
    13621 caccagcagc accccggcga ccagcggccc ggcctcgggg aagagtgcgg tgcacagggc
    13681 caccgagagt gcggggccca cgacgaaggt gagttcgtcg acgaccgatt cgagcgagta
    13741 ggcggtgtgc agccggtcgg agcccttgag ggcgtgggtc cagcgggccc tcaccatcgc
    13801 cgccatgttc ggcatcgcgc cggccaccgc cgcgcagccg aacagggtcc aggcgggggc
    13861 gtcgtaccgg gcacagagca gcagcgcgcc gagcgccatc acgctcagcc cggcaatggg
    13921 cggcagcacc cggctctggc cccggcggtc gaccgcccgg gagatccgcg gaccgcagag
    13981 ggccatggac agggtgaagg tggcggagac ggctccggcg aggccgtagt caccgcgcat
    14041 ctgggacacc atcgcgatga tgccgatgcc cgccatggac aggggcatgc gggcgacgaa
    14101 cccggcggcg gtgaaagccc tcgatccggg cgtccggaac aggacgccat aggggttggc
    14161 catgcgcgga cctccggagc agacgtacgg gcgacccttc gcatggcgcg gtcgccaacc
    14221 ttgaacgatc gcttcaattt gaacggtcgt ttcgttttct accctagccc gccgcccgga
    14281 ccgccgccga cccgggcgcg gggaatggcc ggatcccctc cccggacaac ggaaaaggcc
    14341 gcccggacgg atccgggcgg ccttgcgcag ggacgtttca gccctgctgg aacagctctg
    14401 cgggcagggg cttgagcagg gtgtacaggt cgtcggtgat cggccggtcc cagctggcga
    14461 tggtcacgag gacaccgtcg ctgcgatcga actggacgca ggcgatacgg ctctcggaga
    14521 gcttgacgcg gcggacgatc agcagattgt cgccctgcat gacggggacg tcctcggagc
    14581 tgacgacctc gatcggctcg tcgttctcca gggcgaggag cagttgggcc acctcgaagg
    14641 ggacctggcc ctcctcggtc tcgcgggcgg gcgagccttc cggcagattg ccgatgatca
    14701 tcgccgggcc ccggccgccg tacaggtcgt aacggaggaa gacgccctga cagctgccgt
    14761 cgggggcggg gagcagaccg gcgccgaggt tgccgggcca gtccccgggg tccatggcca
    14821 ggacgtcgaa gtccgggccc gcgggtgttg cggcgctacg gcggcggagg aaggacatgc
    14881 tgccatgtta cgtgtcccgg ctcacgttgc ggagccgggc ccgggccccg tgggaccggg
    14941 ccggccgcat tccctcagcc gggcggcggc tccgctccga cgagccacat ggcgaagaac
    15001 tgcgcccctc cgccgtaggc gtggccgagc gccctggtgg ccccgtcgat ctggtgctcc
    15061 ccggcccgcc cccgtacctg cagggccgcc tcggcgaagc ggatcatgcc ggacgcgccg
    15121 atggggttgg tggacagcac accgcccgag gggttgacgg ggaggtcgcc gtcgagttcg
    15181 gtgacgccgg cctcggtgag cttccagccc tcgccctcgt cggcgaagcc gaggttctcc
    15241 agccacatcg gctcgtacca ggagaacggc acgtacatct cgacggcgtc gatctcccgg
    15301 cgcgggtcgg tgatccgggc ctgccggtag acgtcggccg cgcagtcctt gcctgcctgc
    15361 ggggagacga agtccttgcc cgcgaacagg gtcggctcgc tccgcatcgc cccgccgtgg
    15421 acccaggcgg acgggtgggg cgagcgggcc gcgccctccc ggtcggtgag gatcatggcg
    15481 caggccccgt cggaggaggg gcaggtctcg gagtagcgga tcgggtccca gagcatgggg
    15541 gcggcccgga ccttctccag ggtgatgtcg tggtcgtgga ggtgcgcgta ggggttcttc
    15601 agcgcgttgc ggcggtcctt gtacgcgacg agcgatccga ccgcgtcggg cgctccggtg
    15661 cgcctcatgt acgcccgcac gtgcggggcg aagaaacctc ccgctccggc cagcagcggc
    15721 tgctggaagg ggacgggcag ggagagcccc cacatggcgt tggactcgga ctgcttctcg
    15781 aaggcgaggg tgaggacggt ccggtgcact cgggcggcga cgaggttggc ggcgaccagc
    15841 gcggtcgatc cgccgaccga gcccgccgtg tggacgcgca gcatcggctt gccgacggcg
    15901 ccgagggcgt cggcgaggta gagctccggc atcatgacgc cctcgaagaa gtcgggcgcc
    15961 ttgccgatca cgacggcgtc gatgtcgctc caggtcagcc cggcgtcctc cagtgcccgg
    16021 acggcggcct cgcggaccag tccggcgatg gacacgtcgt gccgggcggc gacgtgcttg
    16081 gtctggccga tgccgacgac ggcgacgggc tccttagaca tgggcactct ccccttccag
    16141 gacggcgacc aggttctgtt gcaggcaagg gccggaggtg gcgtgcgcga gcgcccggtc
    16201 ggactcgccc cggtggatgc gggcggcggc ctcgccgagc cggatcagcc cggcggccat
    16261 cacggggttg gcggcgagcg caccgcccga agggttgacg cggacctcgt cgccgagacc
    16321 gagcgccttg cgcaggatga cctcctggga ggtgaacggg gcgtgcaact ctgctgtgtc
    16381 gaccggccgt tcgaagactc cggcgcgctc tgcggcgagc cgcgcggagg ggctgtcggt
    16441 gaggtcgcgg acgccgaggg cgtgcgcctc gatccggtgg tcgatgcccc ggatccaggc
    16501 gggccgcgcg cacagggcgc gggcggtgtc cccggcggcg aggaccacgg cggcggcgcc
    16561 gtcgccgatg ggcgggcagt cgccggtgcg cagggggtgc accaggtaat cgcccgcggg
    16621 gacgtcgccg gtgagctggg cgtacgggtt gtcggcggcg gctgcgcggt tgcgggcggc
    16681 gacctcggcg agggctcctt cgtcggtggc gcccgcgtcg atgagggcct gcgcctggag
    16741 ggccgcgagc gccaccgagt ccggccagag cggggcgagg tagtaggggt cgagctggcg
    16801 ggtgaggacg tcgcgcaccc ggccgggcga ggacttgccg taggagtaga cgagcgcggt
    16861 gtccgcctcg ccggtctgga tcttcaccca cgcctcgtac agcgcccagg ccccgtccat
    16921 ctcgacgtgg gactcggaga tgggcggatg cgcgccgacg ccgtcgagcg ccatggtgaa
    16981 ggagaaggcc cgccccgcga ggtagtcggc ggagccggag caggtgaacc cgatctcgtt
    17041 cgccttgagg ccggtcgcgc ccaggacctc gtggaggacg ggcatcagca ggtcgacctc
    17101 ggacagttcg tcggtgcgcc ggcggtgcgt ggtctgggcg aaggcgacga tggccacatc
    17161 ccgcatctac accagctcct tgtacgtgtc gtagtcggcg tcgggctcgc cggagggccg
    17221 gtagtggtcc gggtggcggg ctcccgccac ccagacgggc tcgacgcgca gccccatgcg
    17281 cacctggtcg tacgggattc cggcgatgcg tccgtggagg gccaggtcgg cgccgtcgag
    17341 ggcgatgtgg gcgtatacgt acgggacttc gatgtcgagg ttcttcgctt tgatgttgac
    17401 gatgcagaac gtggtgaccg tgccgcgcgg gccgacctcg acctgctcgg cggtggcgac
    17461 cccacaggtg gggcaggctc cgcgcggcgg gacgtagacc ttgcggcagg cggggcagcg
    17521 ttcgccgacg gtgcggtggc cttcgagggc ggcgaggtag gcgctctggg cgcggcccgg
    17581 ggtgtggacg tagtcgaggc gggccggggt gacgatgccg gtgacgggtt cggcgaactc
    17641 ccctgtgtgc ggtgccggtt cggaggcgcc gggctcgccg tcgtacggct cgaagcaggc
    17701 gatgtcggtg atggctccgg tgcgcgtagc ggcccagcgg atgcggacgc gcattccggt
    17761 ccgcacggcg tccgggccgg gcgcgtcgag cgcgtgcagg agtgcggtgc cggccccgtc
    17821 gaggcggaca agcacccagg cgaagggggt gccgagtggc tggtcgcggc ctggggacgg
    17881 gttccaggcc caggtggtga cggtgccggt gggggcgacc tcgacgaggt cgcggatctc
    17941 gttcgcggtg acggggtcgt actccacggg aggcacgagc accgtgccgt cctccgtgcg
    18001 gacgccgagg acggtgcgtt cgcgcagtcc ggtgaggaag gcgctctgga cggggccgag
    18061 cgagcgggtg aaggggaatt cgaccaccag cggggcgctg aggacgtcgg acatggctac
    18121 agcctccttg aatcggggct caggggcagg ctcggcgctc aggcgcgccg gtagacgggc
    18181 ggtcgcttct cggcgaaggc ccgcgcaccc tccttggcgt cctcggtggc gaatacgggc
    18241 cagccgcgct tgagttcggc ggccagcgcc tcgctctccg tcagctccgc accctcgtag
    18301 accgaggcct tgacggcctc gacggcgagc ggcccgcagg cgttgacccg ctcggcgacg
    18361 acgagggcct cctccagcgc ggttccgtcg ggcacgaccc tgccgatgag cccgatggcg
    18421 gcggcctcgt cggcggtgta cgggcggccg gtgagaagca tttcgagggc gtgggtgcgg
    18481 gggatctgac ggggcagccg gaccgtggag ccgccgatcg ggaagaggcc ccggcggacc
    18541 tcgaagagcc cgaaggtggc tcccgctccg gcgatgcgga tgtcggtgcc ctgcaggatc
    18601 tcggtaccgc ccgcgacaca ggggccctcc acggcggcga tcaccggttt gcgcggccgg
    18661 tggtggcgca gcatcgcctt ccagtggagg tcggggtcgg ccgtcatccg ctcccggtac
    18721 tgctccccct ccattcctcc gcccgccagg gccttgaggt ccatgccggc gcagaacgcg
    18781 ccgccggctc cggtcaggac gacggagcgg accgtgtcgt ccgcgtcggc cgcgagccag
    18841 ccgtcgtaca gaccgacgag catcggcagc gagagcgcgt tcctggcctg tggtctgttc
    18901 aaggtgagta ccagcgtggc gccttcgcgc cgcacggtga ggtgttccgt accgcccatg
    18961 accgactcct gtctccagac ctggaacagg ttgcaggagg agggggcgca gttcaatagt
    19021 tttctgacag ctcgtcagat tctttcgacg ccaccccttc ccacttgtgc cgcccggcgc
    19081 tctaatgacg gccgagtcgc cagtcacccg gggtcaggag gaacggtgga gtacaacctt
    19141 gccgacctgt tcgagtcggt cgtcgacgcg gtgtccgacc gcgaggcgct cctgtacgtc
    19201 gaccatcccg gtacgggcgc ggagcggcgg ctcacgtacg cggagctgga cgcagccgcc
    19261 aaccggatcg cccaccatct gatcgacgcg gggatccgcc cgggcgagca cctggggctg
    19321 cacctctaca acggggtcga atatctccag acggtcctgg gggccctcaa ggcgcggatc
    19381 gtcccggtta acgtcaacta ccgctacgtc gaagaggagt tggtctatct ctaccgggac
    19441 gcggacctgg cggcgctggt cttcgacggc gagttcgacg agcgggtcgc gacggccgcc
    19501 ccgcaggccc cgggcctgcg ccatctggtg cgggtggggc ccgcacccgc cgctcccccg
    19561 gccgtgccgg tcgtgccgtt caccgaagcg gagaggtcgg gcgggtccgg gcggggcttc
    19621 gccccccgct ccgccgacga ccagttcatc atctacaccg gcggcacgac cggcatgccg
    19681 aagggcgtga tgtggcgcca ggaggacctg ttcttctcgg gcctgggcgg tggagcaccg
    19741 accggcgagc cggtgaaggc cccgcaggag ctggcggagc gggtcgccgc gggcggggac
    19801 gggatcacct tcttccccac cccgccgctg atgcacggga cctccacgct gaccgcgttc
    19861 atcggcttca acttcggcca acgtgtcgtc gtgcaccgca agttcgtgcc tgccgaggtg
    19921 ctgcggacga tcgagaagga gaaggtcacc agtgtgtcgc tggtcggcga cgcgatgctg
    19981 cgcccgctga tcgactgcct gaacgggccg ctgcgcggga cggactgttc gtcgctgttc
    20041 tccgtctcca gctccggggc gatcatgtcg gactcggtgc gggcggagtt ccaggcgctc
    20101 gtgccgaccg tgatgctgtt gaacaacttc ggctcctcgg agtccggttt caacggcacg
    20161 gcgacggccg attcgggccc ggagcgtggc ttccgggtcc aggtcaacgc ccgtacggcc
    20221 gtggtggatc cggtgacgta cgagccggtg gcccccggcg agccgggccg tatcgcccag
    20281 cgcggtcatg tcccgctcgg ctactacaac gacccggcca agaccgccga caccttcttc
    20341 cgcaggggcg aggagcggtg ggtgctgctg ggcgacatgg cgaccgtgga cgcggacggg
    20401 atcgtcaccg tgctcggccg gggctcccag tgcatcaaca ccgggggcga gaaggtgtat
    20461 ccggaggagg tcgagcaggc gctcaagtcc cacccggacg tgtacgacgc gctcgtcgcg
    20521 ggcgtacccg acgagcgctg gggcaaccgc gtcgccgccg tggtccaact gcggcagaac
    20581 attgaggcgt tgacgctgga ggcggtgcag gcgcactgcc ggaccaggct cgccggctac
    20641 aagatccccc gcgcgctggt actcgccgac cggatccagc gctcgccgag cggcaaggcg
    20701 gactaccggt gggcgaaagc ggtggcggcg ggggccgacc agggctgagg ggtgcgcccg
    20761 ggggccgcgt gggtgtgagt gtcgcccccg taggatcggg taccgatatc ggtttcgtca
    20821 ctgccggagg tgtccaggtg cgggagttcc agcggggtgc ggtgcggctg cacatcctgc
    20881 accacgcggc cgaggaggag atccacgggg cgtggatgac cgaggagctg gcgtcccacg
    20941 gctatcggat cagccccggc accctgtacc cgacgctgca ccggctggag gcggacgggc
    21001 tgttggtctc cgagcagcgg gtggtcgacg gacgcacccg gcgtgtctac tgggcgaccg
    21061 aggccgggaa gaaggccctg gacgaggacc gtcgggcact cagggagctg gcgcgcgagg
    21121 tgctgggcgg cgacggggca ccgtagcgcc cggccggtcg gcgtgttcct cggcagcctg
    21181 gcgatgtccc gtctccgccg cgccggccgg ccgggcaggg cgaccgtctg accgtcggtc
    21241 acgccctgtg tgcggccacc gcgcgccgga ccccgtaggc ggcggcgccg agggccagga
    21301 ccgaggcgcc ccagatcacc gaggacaccg ggagggcgaa cgccagaacg aggcagccgg
    21361 ccagcccgag gacagggatc gccctggccg ggcggccctc gtccggggtc agggtccagg
    21421 cggaggcgtt ggcgatggcg tagtacgcca ggacgccgaa ggaggagaac ccgatcgccc
    21481 cgcgcacgtc cccggccgcg acgaccacgg ccaccacagc gcccaccagg agctcggcac
    21541 ggtgcggcac cttgaacttc cggtggaccg cggccagacc gcggggcagg tgccggtcac
    21601 gggccatggc caaagctgtg cgcgagacgc ccagaatcag tgcgagcagc gagccgagcg
    21661 cggccaccgc cccaccgacg cgcaccaccg gcaccagcca gtcggcacct gccgcccggg
    21721 ccgcgtcgga caggggcgcg gcggcccgcg ccagcccctg cgggcccagg acgctcagca
    21781 cggcgaccgc gacgacggcg tagacgacca gggtgatacc gagcgcgatc gagatgcccc
    21841 gggggatggt gcgccgcggg tcacggacct cctcgccgag agtggcgatg cgcgcgtatc
    21901 cggcgaaggc gaagaacagc aggcccgccg cctggagcac cccgccgaag gtcgcgtcgt
    21961 ccccgacggc gagccgggcc gcactcgacg cggaagaggt gagggaggcg accaccacga
    22021 aggccagcac cgccaggacc acggccacca ccacccgggt cagcatcgcc gacttccgca
    22081 ccccggcgta gttcaccgcg gtcagcgcca ccaccgccgc gaccgcgacg gcgtgctcct
    22141 ggccgggcca tgcgtacgag cccaccgtga gcgccatggc cgcacaggaa gcggtcttgc
    22201 ccaccacgaa ggcc
//
