LOCUS       NZ_JALNTO010000004     12184 bp    DNA     linear   CON 06-NOV-2024
DEFINITION  Bacillus sp. 2CMS4F NODE_4_length_225136_cov_450.157981, whole
            genome shotgun sequence.
ACCESSION   NZ_JALNTO010000004
VERSION     NZ_JALNTO010000004.1
KEYWORDS    WGS; RefSeq.
SOURCE      Bacillus sp. 2CMS4F
  ORGANISM  Bacillus sp. 2CMS4F
            Bacteria; Bacillati; Bacillota; Bacilli; Bacillales; Bacillaceae;
            Bacillus.
REFERENCE   1  (bases 1 to 225136)
  AUTHORS   Gonzalez-Pimentel,J.L.
  TITLE     Bacteria from caves and mines of Spain and Portugal
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 225136)
  AUTHORS   Gonzalez-Pimentel,J.L.
  TITLE     Direct Submission
  JOURNAL   Submitted (25-MAR-2022) Agroquimica, Microbiologia Ambiental y
            Conservacion de Suelos, Instituto de Recursos Naturales y
            Agrobiologia, Av. Reina Mercedes 10, Sevilla 41012, Spain
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: 2021
            Assembly Method                   :: SPAdes v. 3.14.1
            Genome Representation             :: Full
            Expected Final Version            :: No
            Genome Coverage                   :: 200x
            Sequencing Technology             :: Illumina NovaSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_023161785.1-RS_2024_11_06
            Annotation Date                   :: 11/06/2024 09:34:24
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.8
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 4,305
            CDSs (total)                      :: 4,253
            Genes (coding)                    :: 4,106
            CDSs (with protein)               :: 4,106
            Genes (RNA)                       :: 52
            rRNAs                             :: 1, 3, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 3 (16S)
            tRNAs                             :: 42
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 147
            CDSs (without protein)            :: 147
            Pseudo Genes (ambiguous residues) :: 0 of 147
            Pseudo Genes (frameshifted)       :: 92 of 147
            Pseudo Genes (incomplete)         :: 86 of 147
            Pseudo Genes (internal stop)      :: 17 of 147
            Pseudo Genes (multiple problems)  :: 44 of 147
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 16:12:11
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 70493
            Orig. end                         :: 82677
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            JALNTO010000004.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..12184
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="RiPP-like"
                     /region_number="1"
                     /rules="(strepbact or Antimicrobial14 or Bacteriocin_IId or
                     BacteriocIIc_cy or Bacteriocin_II or Bacteriocin_IIi or
                     Lactococcin or Antimicrobial17 or Lactococcin_972 or
                     Bacteriocin_IIc or LcnG-beta or Cloacin or Linocin_M18 or
                     TIGR03651 or TIGR03693 or TIGR03601 or TIGR03795 or
                     TIGR03975 or DUF692 or TIGR01193 or (YcaO or TIGR03604))"
                     /tool="antismash"
     cand_cluster    1..12184
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193 or (YcaO or
                     TIGR03604))"
                     /kind="single"
                     /product="RiPP-like"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..12184
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[5000:7184](-)"
                     /cutoff="20000"
                     /detection_rule="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193 or (YcaO or
                     TIGR03604))"
                     /neighbourhood="5000"
                     /product="RiPP-like"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(5001..7184)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193 or (YcaO or
                     TIGR03604))"
                     /neighbourhood="5000"
                     /product="RiPP-like"
                     /protocluster_number="1"
     gene            38..463
                     /locus_tag="MTN95_RS08570"
                     /old_locus_tag="MTN95_08570"
     CDS             38..463
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003242533.1"
                     /locus_tag="MTN95_RS08570"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MTN95_08570"
                     /product="DUF5391 family protein"
                     /protein_id="WP_105954694.1"
                     /transl_table=11
                     /translation="MSRKNSVVIMTAISGFLFCVMIAAASLSPLADTGSSANQFNSIGM
                     WSAIGMILVFYLIPILIYMLGVDAMRFVMAALCGMGLLIHLSTAAIVLMVSIFGDHPLS
                     DVTTVMGLCLASAAVNIIWFFAAFRSAPKKPVTRDFT"
     gene            complement(586..1923)
                     /locus_tag="MTN95_RS08575"
                     /old_locus_tag="MTN95_08575"
     CDS             complement(586..1923)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Aldedh"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1017: aldehyde dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391865.2"
                     /locus_tag="MTN95_RS08575"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MTN95_08575"
                     /product="aldehyde dehydrogenase family protein"
                     /protein_id="WP_105954580.1"
                     /sec_met_domain="Aldedh (E-value: 8.1e-99, bitscore: 325.0,
                     seeds: 89, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEQQVKDDIQRVFQLQKKQQKVLRASTAEQRKEKLQRFLNSVIAH
                     EEEIIEAIRKDVRKPYHEVKKAEIEGTKKAIRDNMNNLETWMAPKEVGSSLSSDANGIL
                     MYEPKGVTLILGPWNYPFMLTMAPLAASIAAGNSAIVKLSDFTMNTSNIAAKVIRDAFD
                     EKEVAIFEGEVEVATELLDQPFDHIFFTGSTNVGKIVMTAAAKHLASVTLELGGKSPTI
                     IDSEYDLLDAAKKIAVGKFVNAGQTCIAPDYIFIKKDVQDKFAGILQTIVNAGFMEDDY
                     TPDRNKFTQIVNDRNFNRVKALYDDAIEKGAEVVFGGVFDASDRTISPTVLKNVTPDMK
                     IMQEEIFAPILPMMNYEDIDEVIDYVNDRDKPLALYVFSHNQDLIDNVLQHTTSGNAAI
                     NDVVVHFSDVNLPFGGVNTSGIGSYHGVYGFKEFSHEKGVFIQAAK"
     gene            2065..3207
                     /locus_tag="MTN95_RS08580"
                     /old_locus_tag="MTN95_08580"
     CDS             2065..3207
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1215: TetR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391864.1"
                     /locus_tag="MTN95_RS08580"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MTN95_08580"
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="WP_248337785.1"
                     /transl_table=11
                     /translation="MAESAEAQVKQALLALLEERDIQHITMKEIAEKAKVSRGTLYLYY
                     EDKFSIIEDVIEDMKEGLGEALYDAFKHMDTLHLNKKRHTVHPTLSFVHEHRSFFGTMM
                     NREHFHRFFKDVFQQDVLLAPVNVNLTPIEQEIYGHYRALYTYAIILYWLNEDADASPE
                     AISQKVWELVSQKRFYWLFGQAPSRERQEDKQIDRRVVRTREALQKALLDVLAEKKDYA
                     AITISDITRKSNIRRATFYDHYASKEELLQTMIQQSCTEMIDHLTIASSPNELSLKEAE
                     EALAGLLSALDRMPIVHLLNRDWGVPHVIPEMLQALESFYLHQQTNIPAEKKLYAYYVS
                     AMIIGLILYRLEEGKVHAPEVLAREFLQFLDVKKYKVVLL"
     gene            complement(3531..5000)
                     /locus_tag="MTN95_RS08585"
                     /old_locus_tag="MTN95_08585"
     CDS             complement(3531..5000)
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1029: RND family
                     efflux transporter MFP subunit"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014481437.1"
                     /locus_tag="MTN95_RS08585"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MTN95_08585"
                     /product="HlyD family efflux transporter periplasmic
                     adaptor subunit"
                     /protein_id="WP_248337787.1"
                     /transl_table=11
                     /translation="MKRNFFNLNDLRDSREFYESKPKPIGVFFTYILIALLIACIVFSF
                     YGKKEVILKTTADIQYTKPNSNVTNEVAGKVKTVDIKQVDKVKKGDTLLTLDNTEIQAQ
                     KKAVKEDIKDLKEQAALNKTLKKSIENDKNLFSENDHWGYQDQYLSYEKQSNLLESSKE
                     NAKTQQKKLKKQKKSIKNSLDKTKNKVKLKLQRISDLQDSIKNNKSFAKQDDKYNSYYN
                     SYQTNKQNVEQQLDDLQKMKDELDKNSFSQQKENLNGQLESLKQDMLVKLSEEKDELNQ
                     SLDEINSSMKSDDSDSDSDNSEETNYKLSIEQLKTNLLNQTSQKQTDLQTTLKSKEDDL
                     KMLDLQLEKYKIKATSDGYVNVLTNISPGDNLQAGTAILTIVPDKEKLRANIYIPSHEI
                     TNINEKDEVRFHIENTNQTIKGVIIKISPDSISDQNGQKFYIAESTIESKEIVKDNGTK
                     IHLKNGMQTDVSIIVDSKRYIDYFLDVLHLR"
     gene            complement(5001..7184)
                     /locus_tag="MTN95_RS08590"
                     /old_locus_tag="MTN95_08590"
     CDS             complement(5001..7184)
                     /GO_component="GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0008233 - peptidase activity [Evidence
                     IEA]"
                     /GO_function="GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RiPP-like: TIGR01193"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_C39"
                     /gene_functions="transport (smcogs) SMCOG1288: ABC
                     transporter related protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014481436.1"
                     /locus_tag="MTN95_RS08590"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MTN95_08590"
                     /product="peptidase domain-containing ABC transporter"
                     /protein_id="WP_105954577.1"
                     /sec_met_domain="Peptidase_C39 (E-value: 4.6e-44, bitscore:
                     143.3, seeds: 36, tool: rule-based-clusters)"
                     /sec_met_domain="TIGR01193 (E-value: 1.3e-237, bitscore:
                     784.5, seeds: 5, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MFFNRYHCVRQLDQKDCGAACLSTIAKHYGSKLSLAYIRDIAGTD
                     TQGTSALGMVKAAEQLGFSAKAVRAEHTAFDQSITLPAIAHIIIDQQLLHYVVIHKISK
                     DKIIIADPGKGLVTYQKDDFFKIWTGILILLAPTETYKKQTETSNISADIFRLILQQKS
                     LIIHTFLASFIITVFGILGTFYFQTIIDQILPNGLSNTLHILSIGLLIMYLFKVFLIGF
                     RQYLMILLGQKLSISIMFGYFQHVLTLPMKFFSNRKVGEIISRFTDANKVIDAVVSASL
                     SVILDTIMLIMVGIFLYLQNTTLFLITLAFIPFYILTVWIFIKPYENINNTEMENNAQL
                     TSKIVETLNGIETVKAYNAEYMMSFETEKRFVKYLRSAFKHGVIDNLQGSIKMFLDLAS
                     GALILWIGSTQVMKGTLTIGQLITYNALLTYFLNPLQNIIGLQSKLQSASVASKRLGEI
                     LKLEPELIEKEARITSTSSITGPLSFKKINFRYGTRRLILKDITLHIQKGEKVAFVGES
                     GSGKSTLTKLLMKFYTAESGEVLINGYHINDIHTNALRESISYIPQESHFIQGSILENL
                     LLGNSGSFTFEEIIEVCKQTKVHDFINDLPMRYDTLVEENGSNLSGGQKQRLAIARALL
                     RKPNILIMDESTSNLDTTTEQGISKMIYDQTVDVTTIIIAHRLSTIMNCDKIFVMENGE
                     IIEYGNHNDLLKKKGKYYELWENQMPSREMVTI"
     misc_feature    complement(7385..7400)
                     /note="TFBS match to ColR, Phenol-responsive regulator,
                     confidence: weak, score: 22.73"
                     /tool="antismash"
     gene            7598..7816
                     /locus_tag="MTN95_RS08595"
                     /old_locus_tag="MTN95_08595"
     CDS             7598..7816
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018664240.1"
                     /locus_tag="MTN95_RS08595"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MTN95_08595"
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="WP_105954576.1"
                     /transl_table=11
                     /translation="MNNNLKLERTRANLTQEQLAEKIGVTRQTIGLIEKGKYNPSLQLC
                     LKICIELKVTLNDVFWTYNREEETNEG"
     gene            7806..8231
                     /locus_tag="MTN95_RS08600"
                     /old_locus_tag="MTN95_08600"
     CDS             7806..8231
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF042802.3"
                     /locus_tag="MTN95_RS08600"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MTN95_08600"
                     /product="DUF6773 family protein"
                     /protein_id="WP_095431017.1"
                     /transl_table=11
                     /translation="MKDERISHIENKIGHESFLLVIALVFVSFILSIMFKMPSTLMTII
                     ILFVGSGYYGLRAMSKGILRVNLKKKKKSSYFLLIVFTFILYMATSVLFKIITFPFTTK
                     EFLFQILMYILWLIPFSLIMYTTYKFSNRQQKKELEN"
     misc_feature    complement(8232..8250)
                     /note="TFBS match to DmdR1, Iron(II)-dependent repressor,
                     confidence: medium, score: 26.61"
                     /tool="antismash"
     misc_feature    8260..8278
                     /note="TFBS match to DmdR1, Iron(II)-dependent repressor,
                     confidence: weak, score: 24.61"
                     /tool="antismash"
     gene            8424..8654
                     /locus_tag="MTN95_RS08605"
                     /old_locus_tag="MTN95_08605"
     CDS             8424..8654
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="MTN95_RS08605"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="MTN95_08605"
                     /product="hypothetical protein"
                     /protein_id="WP_024123461.1"
                     /transl_table=11
                     /translation="MNAKSIKDVELQALTLEEAEQIDGGSYAKYLGSAVVTGAGAGVVG
                     GVPGVILGAHAGAIAGSVGYLGGSLIAGKWL"
     gene            8671..8895
                     /locus_tag="MTN95_RS08610"
                     /old_locus_tag="MTN95_08610"
     CDS             8671..8895
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="MTN95_RS08610"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="MTN95_08610"
                     /product="Blp family class II bacteriocin"
                     /protein_id="WP_024123460.1"
                     /transl_table=11
                     /translation="MENNNRLSELNVKEMEQIDGGGWRSALGGAFSGALVGASTVGVGG
                     AAVGGPVGGAGGAITGGIVGGIVGGINAW"
     gene            complement(9043..9864)
                     /locus_tag="MTN95_RS08615"
                     /old_locus_tag="MTN95_08615"
     CDS             complement(9043..9864)
                     /NRPS_PKS="Domain: PKS_KR (7-160). E-value: 2.7e-10. Score:
                     32.4. Matches aSDomain:
                     nrpspksdomains_MTN95_RS08615_PKS_KR.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) adh_short"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) adh_short_C2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1001: short-chain dehydrogenase/reductase SDR"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391863.2"
                     /locus_tag="MTN95_RS08615"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MTN95_08615"
                     /product="SDR family oxidoreductase"
                     /protein_id="WP_248337789.1"
                     /sec_met_domain="adh_short (E-value: 2.2e-34, bitscore:
                     112.8, seeds: 230, tool: rule-based-clusters)"
                     /sec_met_domain="adh_short_C2 (E-value: 2.6e-39, bitscore:
                     129.4, seeds: 47, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MGRLDNKTAVITGAATGIGQATAEVFANEGARVIVGDMNEDQMKE
                     TVEAIRQNGGQAEAFHLDVSDEENVKQFADQLKDAYGTIDILFNNAGVDQEGGKVHEYP
                     VDLFDRIIAVDLRGTFLCSKYLIPLMLEKGGSIINTSSMSGRAADLDRSGYNAAKGGIT
                     NLTRAMAIDYARSGIRVNSISPGTIETPLIDKLAGTKEQEMGKKFREANKWITPLGRLG
                     KPKEMATVALFLASDDSSYVTGEDITADGGIMAYTWPGKMLIDEKWKEETK"
     aSDomain        complement(9385..9843)
                     /aSDomain="PKS_KR"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_MTN95_RS08615_PKS_KR.1"
                     /evalue="2.70E-10"
                     /label="MTN95_RS08615_PKS_KR.1"
                     /locus_tag="MTN95_RS08615"
                     /protein_end="160"
                     /protein_start="7"
                     /score="32.4"
                     /specificity="KR activity: inactive"
                     /specificity="KR stereochemistry: C1"
                     /tool="antismash"
                     /translation="TAVITGAATGIGQATAEVFANEGARVIVGDMNEDQMKETVEAIRQ
                     NGGQAEAFHLDVSDEENVKQFADQLKDAYGTIDILFNNAGVDQEGGKVHEYPVDLFDRI
                     IAVDLRGTFLCSKYLIPLMLEKGGSIINTSSMSGRAADLDRSGYNAAKG"
     CDS_motif       complement(9760..9837)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_MTN95_RS08615_0001"
                     /evalue="1.30E-05"
                     /label="PKSI-KR_m1"
                     /locus_tag="MTN95_RS08615"
                     /protein_end="35"
                     /protein_start="9"
                     /score="17.8"
                     /tool="antismash"
                     /translation="VITGAATGIGQATAEVFANEGARVIV"
     gene            9983..10234
                     /locus_tag="MTN95_RS08620"
                     /old_locus_tag="MTN95_08620"
     CDS             9983..10234
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391862.1"
                     /locus_tag="MTN95_RS08620"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MTN95_08620"
                     /product="hypothetical protein"
                     /protein_id="WP_024123458.1"
                     /transl_table=11
                     /translation="MKIQHKKELKFYCLITIPAAFAVLTVISFLLQEITFPVTASAFLN
                     ASWHNLLFLIPFCLFFYPVHIWMKREFSRWNDAGQKRG"
     misc_feature    11474..11489
                     /note="TFBS match to ClgR, Caseinolytic protease gene
                     regulator, confidence: weak, score: 20.91"
                     /tool="antismash"
     misc_feature    complement(12048..12063)
                     /note="TFBS match to AfsQ1, Two-component system AfsQ1-Q2,
                     activator of antibiotic production, confidence: weak,
                     score: 16.72"
                     /tool="antismash"
ORIGIN
        1 aggttaatat ttctatttta ggaggtgtca attgatcatg tccagaaaaa atagcgtggt
       61 gatcatgact gcgatttctg ggttcctttt ttgcgtgatg attgctgcgg cttcactttc
      121 tccgctggca gacacggggt cctcagccaa tcagttcaac tctatcggta tgtggtcggc
      181 aattggtatg atacttgttt tctatctcat tccaatcctc atttacatgc tgggtgtgga
      241 tgcaatgaga tttgtgatgg cggcgctttg cggcatgggt ttgctgattc acttatctac
      301 tgccgccatt gtgctgatgg tcagtatatt cggtgaccat ccgctctctg atgtaaccac
      361 tgtgatgggg ctctgtctcg cttcagcggc tgtaaacatc atttggtttt ttgcagcgtt
      421 tcgttctgcg ccaaagaaac ctgtcacaag ggattttaca tagttttcta ttttgtgtta
      481 atgcatgatt tttctgtgaa ctacatttat ttactgttat gaaactttgt cggcgatgat
      541 agaaaaagag aacctgcaag atgatgcaga ttctctaaat catgtttatt tagctgcttg
      601 aataaacaca cctttttcat gagaaaactc tttaaatccg tataccccat ggtaagagcc
      661 gattccgctt gtatttacgc cgccgaatgg caggttgacg tcactgaaat gaacgacgac
      721 atcattgatc gctgcatttc ctgatgtggt gtgctgaagg acgttgtcaa tcaggtcttg
      781 gttgtggctg aatacataaa gcgctagcgg tttatcgcgg tcatttacgt aatcaatgac
      841 ctcatcgatg tcttcatagt tcatcatcgg caggatcggt gcaaagattt cttcctgcat
      901 gattttcata tctggcgtaa cgtttttcaa aacggttggc gagatcgtac ggtcgcttgc
      961 atcaaatacg ccgccgaaca cgacttccgc gcctttctcg atggcatcat cgtataacgc
     1021 tttgacgcgg ttaaagttgc ggtcattgac aatttgcgta aatttgtttc gatccggcgt
     1081 gtaatcatct tccataaatc ctgcgttgac aatggtttgt aaaatgcctg cgaacttgtc
     1141 ctgcacgtct tttttaatga agatataatc cggtgcgatg caggtttggc cggcatttac
     1201 gaacttgccg acagcaattt ttttcgctgc gtccaataag tcgtattcac tgtcgatgat
     1261 ggtcggactc ttgccgccaa gctcaagcgt gacagatgcc aagtgtttgg cggcggctgt
     1321 catgacgatt tttccgacat ttgtgcttcc ggtgaagaaa atgtggtcga acggctgatc
     1381 aagaagctca gtggccactt caacctctcc ttcaaaaatg gcaacttctt tttcgtcaaa
     1441 agcatctcgg atgacttttg cagcaatgtt gctcgtgttc attgtaaagt ctgacagctt
     1501 cacaatggcg ctgtttcctg cagcgataga agcggcaagc ggcgccatcg tcagcataaa
     1561 cgggtagttc cacggaccga gtataagcgt gacgccttta ggctcgtaca taaggattcc
     1621 gttggcatca gagcttaagg atgaaccgac ttctttgggt gccatccatg tttccaggtt
     1681 gttcatatta tctctgatcg ctttttttgt accctcgatt tccgcttttt tgacctcgtg
     1741 atatggcttc cgcacgtctt tgcggatcgc ttcgatgatt tcctcttcat gtgcaatgac
     1801 ggaattcaaa aagcgctgaa gcttttcttt acgctgttcc gctgttgaag cgcgcagcac
     1861 tttttgctgt tttttctgaa gctggaagac gcgctgaatg tcgtctttta cttgctgttc
     1921 cattgtaaaa tccccctcat ttgctttctg cttatctcgg aactattata aagtggtatc
     1981 ttttctataa gaaagacaac ggagaatcat ctatacgtta ccgtacatat atcgaatatg
     2041 tgtctaatga ctgggggtgt ttttgtggcg gaatctgctg aagctcaagt gaaacaggcg
     2101 ctgctggctt tattggaaga aagagatatt caacacatca caatgaaaga aatcgctgaa
     2161 aaggccaaag tgagccgcgg gacgctctac ctttattatg aagacaagtt ctccattatt
     2221 gaggatgtga tcgaagacat gaaggaaggg ctgggcgaag cgctctatga cgccttcaag
     2281 catatggaca cactccattt aaataaaaaa cggcacactg tgcatccgac tctgtccttt
     2341 gtccacgagc atcgatcctt ttttggcacg atgatgaaca gagaacattt tcatcgtttt
     2401 tttaaggatg tgtttcagca ggatgttttg ctggctccgg tcaatgtgaa tctgacgccg
     2461 attgaacagg agatttacgg acattaccgg gctttgtaca cgtacgcgat tatcctttat
     2521 tggctgaatg aggatgcgga cgcgtctccg gaagccatca gccaaaaagt ttgggagctc
     2581 gtttctcaaa agcggtttta ttggctgttt ggacaggctc cgtcaaggga gcggcaggag
     2641 gacaagcaaa tcgacaggcg tgtggttcga acgagagaag cgctgcagaa ggctttgctg
     2701 gacgtattgg cagagaaaaa agactacgcg gccatcacga tttctgacat tacccggaaa
     2761 agcaatatcc gccgcgcaac cttttatgat cactatgcca gcaaagagga attgctgcag
     2821 accatgattc agcaatcatg tacggagatg atagatcacc tgacgattgc ctcaagtccg
     2881 aatgagcttt ccttaaaaga agcggaggag gcgctcgccg gcctgctttc tgcattagac
     2941 cgcatgccta ttgtccattt gctcaatcgg gactggggtg ttcctcatgt gatacccgag
     3001 atgctccaag cgttggaatc attttatctg catcagcaaa ctaatattcc tgcggagaaa
     3061 aagctttatg cctattatgt atcggcgatg attatcgggc tgatattgta tcggctcgag
     3121 gaagggaagg tgcatgcgcc ggaagtgctg gcgagggagt ttttgcagtt tttggatgtg
     3181 aagaagtata aggtggtatt gctttgaagt gcccggagac ttgatccggg ctttgggtcg
     3241 ttatgatact tggtcttttg attttcttta ttttaaggtg agattgagaa atagaagaga
     3301 caaaagaata aaaacaatat tcaccatcca agacttccag cttacagtgg ggggccaata
     3361 ttgtattgaa gagaaggcga acgattgaag agaataaaaa gagtaaaaat aacagtttgt
     3421 tttgagacat gattctatac gtcctatacc tttcttataa aaaataaaat gcctcaaagc
     3481 agattctcat ctgcttttga gacatatatg cacatttctc taaatggaaa ttaacgtaag
     3541 tgtaatacat ctaaaaaata atcaatatat ctttttgaat caacgataat tgatacatct
     3601 gtctgcatgc cattttttaa atgtattttt gttccgttat ctttaacaat ttctttgctt
     3661 tctatcgtgc tttcagcaat ataaaatttt tgcccatttt gatcactaat actgtctgga
     3721 cttattttga taatgacacc tttaatggtt tgatttgtat tttcaatatg gaatcttact
     3781 tcatcttttt cattaatatt tgtgatctca tgactcggaa tataaatgtt agctctaagc
     3841 ttctctttat cagggacaat agtcaaaata gcagtgcctg cttgtaaatt gtcacctgga
     3901 gatatatttg ttagtacatt aacatagccg tcactagttg cttttatttt atatttttct
     3961 aattgtaaat ctagcatctt tagatcatct tcttttgatt taagagtggt ctgaagatct
     4021 gtttgctttt gagatgtttg atttagcaag tttgttttaa gctgttcaat ggaaagctta
     4081 taatttgttt cctctgagtt atcggaatca ctgtcagaat cgtcactttt cattgaactg
     4141 ttaatctcat caagtgattg atttaattcg tctttttctt cacttagttt tactagcata
     4201 tcttgtttta aactttcaag ctgtccgttt agattctctt tctgctgtga gaaactgttt
     4261 ttatcgagct catctttcat cttctgtaga tcatcaagct gctgctctac attttgtttg
     4321 ttagtttgat aactattata gtaagaattg tacttatcat cctgtttggc aaaggattta
     4381 ttgtttttaa tggagtcttg caggtcagaa attctttgaa gctttagttt cactttgttt
     4441 tttgtcttat ccagactatt ttttatgctt tttttctgct tcttaagttt tttctgctga
     4501 gtttttgcat tttcttttga tgactctaac aaattacttt gtttttcata tgagagatat
     4561 tgatcttgat aaccccaatg atcgttctcg ctgaataaat ttttgtcatt ttcaatactt
     4621 ttttttagag ttttgtttaa cgcagcttgt tcttttaaat ctttgatatc ttctttaaca
     4681 gcttttttct gcgcttggat ttcagtattg tctagagtta atagagtatc tccctttttc
     4741 accttatcaa cctgtttaat atcaactgtt tttactttgc cggctacttc gtttgttacg
     4801 ttgctgttag gcttggtata ttggatgtca gctgtcgttt ttagaattac ttctttcttt
     4861 ccatagaaac taaaaacaat acatgcaata agtaaagcta tcagtatata tgtaaagaaa
     4921 acaccaattg gtttgggttt tgattcgtag aattctctgc tatccctcaa atcatttaaa
     4981 ttgaaaaagt tacgtttcat ctaaattgtc accatctctc tcgatggcat ttggttctcc
     5041 cacaactcat agtacttgcc ttttttcttc aataaatcat tgtggttccc atactctatg
     5101 atttctccat tttccatgac aaatattttg tcgcaattca taattgtact caaacgatga
     5161 gcaattataa tcgtagttac atcaacagtc tgatcgtata tcatctttga tattccctgt
     5221 tcggttgtcg tatcgagatt gctagttgat tcatccatta tgagaatgtt aggttttctt
     5281 aataatgctc tggcaattgc gagtctttgc ttctggcctc cagataaatt agacccgttt
     5341 tcttctacaa gagtatcgta tctcattggt aaatcattga taaaatcatg tactttagtt
     5401 tgtttacata cttctataat ctcttcaaag gtaaaacttc ctgagttccc aagcaaaagg
     5461 ttttcaagaa ttgatccttg tataaaatga gattcttgag gtatataact tatgctttct
     5521 cttaacgcgt tggtgtgaat atcatttata tgataaccat tgattaaaac ctcacctgat
     5581 tcagctgtat aaaatttcat taaaagctta gtcaaagtag attttcctga accgctttct
     5641 ccaacaaagg caactttctc tcctttttga atatgcagtg taatatcttt taagatgagc
     5701 cttcgagttc cgtatcgaaa attgattttt ttaaaagaaa gcggacctgt aattgacgac
     5761 gtcgatgtta ttcgcgcctc tttctctatt aattcgggtt ctagctttag aatttctccg
     5821 agccttttgg acgcaacaga tgctgactga agcttagatt gtaggccgat gatgttttgt
     5881 aaaggattta agaagtaggt taataaggca ttatatgtaa taagctgacc aatagtaagg
     5941 gtgcctttca tgacttgagt tgatccgatc cacagtatca atgcaccgct tgctaaatcc
     6001 aaaaacattt ttatggaacc ctgaaggtta tcaataactc cgtgtttaaa agctgatcgt
     6061 aagtatttca caaatctttt ttctgtttca aatgacatca tatattccgc attgtatgct
     6121 ttaacagttt cgatgccgtt aagcgtctca acaatctttg aagtcagctg cgcattgttt
     6181 tccatttctg tgttatttat attttcgtag ggttttataa aaatccaaac cgtcaaaata
     6241 taaaaaggta tgaaagccaa tgtgatgaga aataaagtag tattctgcag atataagaaa
     6301 ataccaacca taataagcat aatggtatcg agtatgaccg aaagcgatgc actgacaaca
     6361 gcatcgatca ctttattagc atcagtaaat ctggatataa tttcgccgac ttttctattg
     6421 ctgaaaaatt tcattggcaa agtaagcaca tgttgaaagt atccaaacat gatggagata
     6481 cttaattttt gacctaggag aatcattagg tattgcctaa aacctattaa gaaaacctta
     6541 aataaataca taatcaaaag gccgattgaa agaatatgta atgtgttact taatccatta
     6601 ggtaggattt gatcgatgat cgtctgaaag taaaaagtac cgaggatccc gaagacggta
     6661 ataataaagg atgctaaaaa cgtatgtata atcaacgatt tttgctgaag aatcaacctg
     6721 aaaatatcgg cacttatatt acttgtctcg gtctgttttt tataagtctc agtaggtgct
     6781 aaaagtatta agatgcctgt ccaaatctta aaaaaatcat ctttttgata tgtaacgagc
     6841 ccttttccag gatccgcaat gataatttta tctttactaa ttttatgtat aacaacgtaa
     6901 tgcaataatt gttgatctat aataatatgt gcaattgctg gaagagtaat ggactgatca
     6961 aaagctgtat gctctgcacg cacagctttt gctgaaaacc ccaactgttc ggcggctttt
     7021 accattccaa gagcactagt accttgtgta tcagttccag caatgtcacg tatataagct
     7081 agagagagct ttgagccata atgttttgca attgttgata ggcaggctgc tccacaatct
     7141 ttttgatcaa gttgtcgtac acaatgatat ctattaaaaa acatatacta ctctccataa
     7201 tgaaggtcat tttttagaat atatataata atataaagaa tagacatcat tttattacat
     7261 tttcatggtt tgtcaacctt tttaaggtaa atatttattg ttatttagag cttttggcac
     7321 gtttatataa tataaatgcg taattgatat agataagata taaagcaaga ttaaatacac
     7381 ctaagtgaaa aaaataagaa agagatatac aaaataaacc ccctgcgatt ataaagatat
     7441 agaacaattt cattttacca actcctataa atgttaaatt cattgtaaga tataatagac
     7501 taaatgtaaa atatatatgg ataaatgcaa tatatagttt gcatggtttt tttatatatg
     7561 atatgctaca gataaataaa ccaatggaga cttgccaatg aataataatt tgaagttgga
     7621 aagaacaaga gcgaatttaa cacaggaaca acttgccgaa aaaattggag tgacaagaca
     7681 gacgattgga ttaattgaaa aagggaagta taatccttct ttacaattat gtttgaaaat
     7741 ttgtatagaa ttgaaagtta ctctgaatga tgtattttgg acgtataaca gggaggaaga
     7801 aactaatgaa ggatgagaga ataagtcata ttgaaaataa aataggtcat gaaagctttc
     7861 ttttagtaat tgctttggtt tttgtctctt ttatactttc gattatgttt aaaatgccga
     7921 gcacgttaat gacaattatc atattgtttg ttggaagcgg atattatgga ttaagagcta
     7981 tgtcaaaagg cattttaaga gtaaatctga aaaagaagaa gaagagttcg tactttcttt
     8041 taattgtttt tacttttatt ctgtatatgg caacgtcggt attatttaaa atcattacat
     8101 tcccttttac aactaaagaa ttcttattcc aaattcttat gtatatttta tggctaattc
     8161 cttttagtct catcatgtat actacatata aattttcaaa caggcagcag aaaaaagaat
     8221 tagagaatta attaagagag cttaacctaa ataactgaat taggttaagc tctcttttac
     8281 tatatataaa ttgatcgata ggttatagat gattttatgg aaaaaactat tgatttagga
     8341 tttattatgt aatattataa ttcccatggt aaatttatac tagttattat tatttacctg
     8401 aataactttg aggaggaata ttgatgaacg caaaaagcat aaaagacgtt gaacttcagg
     8461 cattgactct tgaagaagct gaacaaattg atggaggaag ttatgctaaa tatcttggca
     8521 gtgcagtagt tacaggtgcc ggcgcaggtg tagtcggagg agttccaggt gttattcttg
     8581 gtgcccatgc aggtgcaatt gcagggtcag ttggttattt aggcgggtca ttaatcgcag
     8641 gaaaatggct ttaaggaggg aatagcataa atggaaaata ataatcgtct ttcagaattg
     8701 aatgtaaaag aaatggaaca aattgatggc ggaggctgga gaagtgccct tggcggagct
     8761 ttttcaggtg cattagtcgg tgcttcaaca gtaggcgtcg gtggagcagc tgttggcgga
     8821 cccgttggtg gtgccggcgg agcaattact ggcggcatag ttggcggtat agttggcgga
     8881 ataaacgctt ggtaataaaa atacataaag aactagtttg aacattatgt aacaagaccg
     8941 gaaagagtat atcttttctc ggtcttgtta tatttgtatt tatatataca taatgttttg
     9001 tagcgtctat ttattataaa ttcttttaac tgactatctc agttattttg tttcttcctt
     9061 ccatttctca tcaatcaaca tcttgccagg ccatgtatac gccatgatgc cgccgtctgc
     9121 ggtgatgtct tcgcctgtga cgtatgagct gtcgtcagat gcgaggaaca gcgccaccgt
     9181 cgccatttcc ttcggtttgc cgagacggcc gagcggcgtg atccatttgt tggcttcgcg
     9241 gaatttcttg cccatttcct gttccttggt gccagctaat ttgtcaataa gcggcgtttc
     9301 aatcgtaccc ggtgagatgg aattgacccg gatgccgctt cttgcgtaat caattgccat
     9361 cgctcttgtc aggtttgtga ttccgccttt tgcggcgtta tagccggagc ggtcaaggtc
     9421 tgcagccctg cctgacatgg aggaggtgtt gatgatggag cctccctttt cgagcataag
     9481 cggaatcaga tatttgctgc aaagaaacgt gccgcgcaga tcgactgcga taatgcggtc
     9541 aaacagatct acgggatatt cgtgcacttt tccgccttcc tgatcgacgc cggcgttgtt
     9601 aaagagaata tcaatcgttc cgtacgcgtc tttgagttga tcagcaaatt gcttcacgtt
     9661 ttcttcatct gacacatcaa ggtgaaaagc ctcagcttgt cctccgtttt gtctgatcgc
     9721 ttcgactgtc tctttcattt gatcttcatt catatcgccg acaatcacac gcgcgccttc
     9781 attggcaaaa acctctgccg ttgcttgtcc aatgcctgtc gcagcgcctg tgatcacagc
     9841 ggttttgtta tcaagtcttc ccataacacg aatcctcctt tttctagttg tcttcccgct
     9901 gtgtgcagtg ataaacatgt gagaaaagta atacctgtat atgttaaaat gaactagaaa
     9961 ttgttgggag gttttatgtg ttttgaagat acagcataag aaggaactca aattttattg
    10021 tctcattacg attccggctg cgtttgctgt gctgactgtc atctcttttt tattgcaaga
    10081 gattacgttt ccggttacag ctagcgcatt tctgaatgct tcatggcata atctattgtt
    10141 tctgataccg ttctgtttgt ttttctatcc ggtgcatatt tggatgaagc gggagtttag
    10201 ccgatggaat gatgcaggac aaaagagagg atgatcctct ctttttcgta tctgaatgtc
    10261 tagaaaaaat agtgaaaaca cacccaacta atgttaaatt tacatatata tgcatctatc
    10321 aatctttgat gaaaaccgta ttgacatgag tcgtcattta tgataaatag atgctgaaaa
    10381 gagtttacat aacatcacaa agcatgaaaa aggagcgagc tgaatggcca aaaaagagtt
    10441 taaagcagag tccaaacgac tgctggatat gatgattaac tccatttaca ctcaaaaaga
    10501 aatctttctt cgcgagttaa tttccaatgc gagtgacgcg attgacaaaa tctattacaa
    10561 ggcgctgacg gatgatgcgc taaccttcga taaagacaat tactacataa aagtcgcggc
    10621 tgacaaaggc gcgagaacac tgaccattac ggatacaggg attggaatga caaaggacga
    10681 gcttgaacag cacctcggta cgattgcgaa aagcggctct cttgcgttta aaaaagaaaa
    10741 cgaactgaag gacggccatg acatcatcgg gcaattcggt gtcggatttt atgcggcgtt
    10801 tatggttgcc gatgtggtga ccgttatcag taaggcgctc ggcagcgaag aagcgtataa
    10861 atgggaatct gctggcgcag acggctatac aattgagccc tgtgaaaagg attctgtcgg
    10921 cacagacatt atcctgaaga tcaaagagaa cacggaagat gagagctatg atgagttttt
    10981 agaagaatat cgtttaaaag cgatcatcaa aaagtactct gacttcattc gctacccgat
    11041 caaaatggat acaacggtta ataagccgaa ggaaggcagc gacaatgaat ttgaagaggt
    11101 gcaggaggaa cagacggtta acagcatggt gccgatctgg agaaaaaaca agagcgagct
    11161 gacagatgag gactatgaaa cgttctattc tgaaaagcat tacggatttg ataaaccgct
    11221 cactcatgtc catatcagtg ttgacggtgc cgtgcgctac aacgccattt tatttattcc
    11281 tgaaaacatg ccgtttgact attattctaa ggaatatgag aaaggcttgg agctctattc
    11341 caacggcgtg ctcatcatga acaaatgcgc ggatctgctt ccggaccact tcagttttgt
    11401 gaagggtatg gttgattctg aggacctgtc gctgaacatt tccagagaaa tgctgcagca
    11461 tgaccgccag ctgaagctga ttgcgaaaaa catcagcaaa aagatcaaaa gcgagctgca
    11521 gagcctgctg aaaaaagaca gagaaaaata tgagaccttc tacaaatcgt tcggcagaca
    11581 gctgaagttc ggcgtgtaca atgattttgg cgcgaataaa gatcaattga aggatctctt
    11641 attattctac tcttccaaag agaaaaaact ggtcagcctg gacgagtacg tatccagaat
    11701 gcctgaagag cagaaatata tttactacgc gaccggtgat tcatatgatc gcattgaaaa
    11761 actgccgcaa acggaaatgg tagcggacaa aggctatgaa attctttact ttacagagga
    11821 catcgatgaa tttgcgatca aaatgctcgc ttcatatcaa gaaaaagagt tcaaatctgt
    11881 ttcaagcggc gatcttggca tcgattcaga agaggatcaa aagcagtctg aagaagagga
    11941 aagcaagtac aaggatctgt ttgaggaaat gaaaaatatt ctgtctgaca aagtgaaaaa
    12001 cgtcagagta tcgaaacgcc tcaaatctca tccggtctgc cttgcagctg acggtgaagt
    12061 gacaatcgag atggaaaaaa tcttaaatgc gatgccggac agccaaaatg taaaagcgga
    12121 caaagtgctg gaaatcaatc cgaatcacga ggtattcaac acgctgcaga acgctttcga
    12181 acaa
//
