LOCUS       NZ_JAHXMW010000003     20873 bp    DNA     linear   CON 13-MAY-2024
DEFINITION  Paenibacillus silvae strain EYE_43 Seq_3, whole genome shotgun
            sequence.
ACCESSION   NZ_JAHXMW010000003
VERSION     NZ_JAHXMW010000003.1
KEYWORDS    WGS; RefSeq.
SOURCE      Paenibacillus silvae
  ORGANISM  Paenibacillus silvae
            Bacteria; Bacillota; Bacilli; Bacillales; Paenibacillaceae;
            Paenibacillus.
REFERENCE   1  (bases 1 to 560849)
  AUTHORS   Pu,J.
  TITLE     Study on the microbiota of ocular surface in healthy people
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 560849)
  AUTHORS   Pu,J.
  TITLE     Direct Submission
  JOURNAL   Submitted (30-JUN-2021) New Pathogen, China CDC, 155 Changbai Road
            Changping District, Beijing 102206, China
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: SPAdes v. 3.13.0
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 200x
            Sequencing Technology             :: Illumina
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_023149095.1-RS_2024_05_13
            Annotation Date                   :: 05/13/2024 05:30:36
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 6,071
            CDSs (total)                      :: 5,941
            Genes (coding)                    :: 5,912
            CDSs (with protein)               :: 5,912
            Genes (RNA)                       :: 130
            rRNAs                             :: 9, 12, 12 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 12, 12 (5S, 16S, 23S)
            tRNAs                             :: 93
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 29
            CDSs (without protein)            :: 29
            Pseudo Genes (ambiguous residues) :: 0 of 29
            Pseudo Genes (frameshifted)       :: 8 of 29
            Pseudo Genes (incomplete)         :: 20 of 29
            Pseudo Genes (internal stop)      :: 3 of 29
            Pseudo Genes (multiple problems)  :: 2 of 29
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 01:11:56
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 168034
            Orig. end                         :: 188907
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            JAHXMW010000003.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..20873
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene"
                     /region_number="1"
                     /rules="(PT_phytoene_like or phytoene_synt or Lycopene_cycl
                     or Lycopene_cycl_fung or T1TS or T1TS_KS or T2TS or TS_UbiA
                     or TS_Pyr4)"
                     /tool="antismash"
     cand_cluster    1..20873
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /kind="single"
                     /product="terpene"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..20873
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:10873](-)"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..10873)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
     misc_feature    complement(555..575)
                     /note="TFBS match to NrtR, NAD synthesis repressor,
                     confidence: weak, score: 23.96"
                     /tool="antismash"
     misc_feature    complement(592..606)
                     /note="TFBS match to MexT, Global virulence regulator,
                     confidence: strong, score: 20.76"
                     /tool="antismash"
     gene            complement(1180..1656)
                     /locus_tag="KZX51_RS12925"
                     /old_locus_tag="KZX51_12885"
     CDS             complement(1180..1656)
                     /GO_function="GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017691916.1"
                     /locus_tag="KZX51_RS12925"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KZX51_12885"
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="WP_248063091.1"
                     /transl_table=11
                     /translation="MELLPMNGEQFASFHSRSIADFAEEKVEAGTWAPEEAQERAEDSY
                     ERYLPEGLETPGAYVYNVVHPVDGIVGYIWFNVTENRRGKEAFLLDIVVEEAHRGKGYG
                     TEAMEALERTARRLGVDRIGLHVFGHNVRASSLYRKMGYEVTDLTMYKEIENRG"
     misc_feature    1723..1736
                     /note="TFBS match to ANR, Anaerobic transcriptional
                     regulator, confidence: weak, score: 20.06"
                     /tool="antismash"
     gene            complement(1863..2033)
                     /locus_tag="KZX51_RS12930"
                     /old_locus_tag="KZX51_12890"
     CDS             complement(1863..2033)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006207952.1"
                     /locus_tag="KZX51_RS12930"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KZX51_12890"
                     /product="aspartyl-phosphate phosphatase Spo0E family
                     protein"
                     /protein_id="WP_111269050.1"
                     /transl_table=11
                     /translation="MDRDELKLRIEEARVKLHRLKTEYGDLLHPKVIHQSMVLDELINR
                     YNHVKRVKPME"
     gene            complement(2282..3601)
                     /locus_tag="KZX51_RS12935"
                     /old_locus_tag="KZX51_12895"
     CDS             complement(2282..3601)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017691549.1"
                     /locus_tag="KZX51_RS12935"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KZX51_12895"
                     /product="transcriptional regulator"
                     /protein_id="WP_248170999.1"
                     /transl_table=11
                     /translation="MTIHRFSEISGVNSGTLSGTLKGLRPIGLNQLDRITAGMGLPEGH
                     LYELYIHEYLIDANLDWRRLRPFLYRCAELGHVSYMETAVRYVADHLSYVPMLFELAEQ
                     LYSEGKLEACIPLYRCVAESEKLQHSERLALSQYRLFSIGLSNDQSNNLTLATQFELFV
                     QRLDEPYQFDALNDLINVYASLRRWDKVKEFADQLQIKAFIQYEAKKTLREVETKTKKK
                     IVFYALYSYLALAEVSYQHGNYEETLQYVSKYADYSWIKDPTEEEKIVILQFQDWSEGN
                     NYYFRLLSGETELIQDYLKYISDRKKEVFPALCAIVTAANRYNINIDSVLDEYQSYLVY
                     EEQSSRLGKMSKQYTNDQYGILLAGLGTYYLRNNDYDRGVGYIRKGMEFAIENMNKDGL
                     LDCLGLFEDLQHYATGRGAKPSAEQLIEKIQRLYSPHVKA"
     misc_feature    3591..3604
                     /note="TFBS match to ArgR, Regulator of arginine
                     biosynthesis genes, confidence: weak, score: 16.99"
                     /tool="antismash"
     gene            complement(4213..5280)
                     /gene="fni"
                     /locus_tag="KZX51_RS12940"
                     /old_locus_tag="KZX51_12900"
     CDS             complement(4213..5280)
                     /EC_number="5.3.3.2"
                     /GO_function="GO:0004452 - isopentenyl-diphosphate
                     delta-isomerase activity [Evidence IEA]"
                     /GO_process="GO:0008299 - isoprenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="fni"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017691913.1"
                     /locus_tag="KZX51_RS12940"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KZX51_12900"
                     /product="type 2 isopentenyl-diphosphate Delta-isomerase"
                     /protein_id="WP_145404441.1"
                     /transl_table=11
                     /translation="MNEQERAGKRLLPEVATGERKLEHVRLCLEQNVAGEGITSGLEKF
                     AFRHHPLPELDFEEVCLDTSFLGKKMRTPLLISSMTGGSQTTGAINERLARVANARGWA
                     LGVGSIRAAVEQPELASTFDVRRWAPDIPVIANLGAVQLNYGFSTADFQRAVEIAGADL
                     LVLHLNTLQEVFQPEGNTNFSGLFQRIESLCRELEVPVGVKEVGFGIDGVTAQRLYEAG
                     VAFIDVAGAGGTSWVQVEKYRNNNPVRRAAAEAFADWGIPTAECIQDVRALNPDGALIG
                     SGGLHTGVDAAKALALGADLAGFGRSLLESAVTSDEALSERLEQVEFELRTVMFGIGAG
                     SIADVKQTERLVARR"
     gene            complement(5750..7270)
                     /gene="crtI"
                     /locus_tag="KZX51_RS12945"
                     /old_locus_tag="KZX51_12905"
     CDS             complement(5750..7270)
                     /EC_number="1.-.-.-"
                     /GO_function="GO:0016166 - phytoene dehydrogenase activity
                     [Evidence IEA]"
                     /GO_process="GO:0016117 - carotenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="crtI"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Pyr_redox_2"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) DAO"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1222: dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017691912.1"
                     /locus_tag="KZX51_RS12945"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KZX51_12905"
                     /product="phytoene desaturase family protein"
                     /protein_id="WP_145404786.1"
                     /sec_met_domain="Pyr_redox_2 (E-value: 6.2e-09, bitscore:
                     30.3, seeds: 64, tool: rule-based-clusters)"
                     /sec_met_domain="DAO (E-value: 2.6e-08, bitscore: 28.6,
                     seeds: 521, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MHNGHREAASVGNSKQDVIIIGAGFGGLSCAIRLASAGLRVTMLE
                     RQEHVGGKLQQIEQNGYHFDRGPSTITMPDAFRSVFDQAGVRMEDYVQLYELEPRTRNV
                     FADGTVVDLSRDRGWMKEQIAAYSPQDAMRYDAFMDESASLYMEANRHFLGKLLLKPSD
                     KYNLQMLRSLLRVRPAVKLDTLLRRYFSHPHTLAMFGRYATYVGSSPYLSPSIFAMMGH
                     VEAEVGIYGVKGGTYQLIEGMTRLAREKGVQIMTGIEVHQIVVRNGKVVGVDTDRGWME
                     ADRIVANGDVLSVNRLLLATEHRKRMNDARIAKYEPSISGFVTLAGVRRQYGQLLHHTV
                     FFPERYEPEFEHIFRDRMMPADPTIYICYSGYSESGMAPAGASNLFILVNAPYLSNAWK
                     WEEQQKCYGEFVLEQLESRGIGGLKQSDVLIRYTPQQIARDTLAHQGSIYGISSNSMKQ
                     TFMRPGNQSSDVQGLWYVGGTTHPGGGTPIVTLSGQLVGEQLAAEMGR"
     gene            complement(7336..8496)
                     /locus_tag="KZX51_RS12950"
                     /old_locus_tag="KZX51_12910"
     CDS             complement(7336..8496)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Glycos_transf_2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1123: polyprenol-monophosphomannose synthase ppm1"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017691911.1"
                     /locus_tag="KZX51_RS12950"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KZX51_12910"
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="WP_248063092.1"
                     /sec_met_domain="Glycos_transf_2 (E-value: 4.2e-25,
                     bitscore: 83.4, seeds: 256, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNEGVGTAEILWMCLVGWLLVQLLFAIWNAACLPQIRSFQRGSIQ
                     PPDLLVSVLIPARNERLHIEECLESVLASHTKGFLMEVLVLDDRSEDETASLVQAIADR
                     DSRVRLLHGTDLPAGWMGKSHACHRLVQEAQGEWFMFVDADVRVKPDAIRQMVAAGCAQ
                     GGGLVTGFPYQVARTWMEKLVVPMMMFTIISHLPIFMIRRSASPMFVAATGAFLLIHRT
                     SYEASGGHAAIQAHLVDDMSLAKAVKRAGHPVLLADVHDVTSTRMYQNGEEVWNGYKKN
                     MYEGMGRRDALLIGTMFMYFMMYIVPPLGLVIGLLTGNETSILYGFIGTLLGVAVKRVS
                     DHIGGQPWWLALFQPISMACVIAIGLASWQAGRSGKGYVWKGRRYS"
     gene            complement(8498..9265)
                     /locus_tag="KZX51_RS12955"
                     /old_locus_tag="KZX51_12915"
     CDS             complement(8498..9265)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017691910.1"
                     /locus_tag="KZX51_RS12955"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KZX51_12915"
                     /product="lysophospholipid acyltransferase family protein"
                     /protein_id="WP_248063093.1"
                     /transl_table=11
                     /translation="MIRAVKSKAFERIFTLYNHYYLLRRRFRSFTLLGSLDPQVPDGNG
                     RLLPTAPDQPIVYFMNHSSWWDGLLLYHAAKQTSRGDHYVMMEERQLRQYAFFRKLGAY
                     SINKDSSSGVRTSLQYTNELLAAGKRVWIFPQGEILHQEARPIQFRPGIGLVLRRFPQA
                     VAVPVTLCHGMVQHDLPEISMQAGSPIVGDWRAWKSEEIAERLGRVLEQQLDEHRAALI
                     RLGQGSLPDAYPLIRGTRSTSEKYDEARRRVNR"
     gene            complement(9234..10001)
                     /locus_tag="KZX51_RS12960"
                     /old_locus_tag="KZX51_12920"
     CDS             complement(9234..10001)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017691909.1"
                     /locus_tag="KZX51_RS12960"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KZX51_12920"
                     /product="carotenoid biosynthesis protein"
                     /protein_id="WP_248063094.1"
                     /transl_table=11
                     /translation="MIQWVYWVWYTIGAILMLTIGVPEVLSFSNGLFLVFYALYVLDLV
                     YQPSNRSALSDQSVKWLRPDLWIASLIIWLGGMGVEWIGVHTHWPFGEYAYSDFFGVHL
                     FSVPVTLGFAWIAVVGNSALISGGGSTWGGKLVRALKTGFWAIVLDLVLDPVAHARGFW
                     EWQSPGGFYGVPWTNYISWFIMGAFLSLFLPAVPNDRRSLLRAKWLYQLFILLFGVLAL
                     KEGITGSFIIAIAGVLLAEGSWLYDPRRKIQSV"
     gene            complement(10001..10873)
                     /locus_tag="KZX51_RS12965"
                     /old_locus_tag="KZX51_12925"
     CDS             complement(10001..10873)
                     /EC_number="2.5.1.-"
                     /GO_function="GO:0004659 - prenyltransferase activity
                     [Evidence IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /GO_process="GO:0008299 - isoprenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: phytoene_synt"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: PT_phytoene_like"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017691908.1"
                     /locus_tag="KZX51_RS12965"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KZX51_12925"
                     /product="phytoene/squalene synthase family protein"
                     /protein_id="WP_111269045.1"
                     /sec_met_domain="phytoene_synt (E-value: 1.3e-48, bitscore:
                     160.4, seeds: 8, tool: rule-based-clusters)"
                     /sec_met_domain="PT_phytoene_like (E-value: 1.5e-69,
                     bitscore: 229.3, seeds: 61, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNEAILSRCEELMQKGSSSFYQAFKGLPSPRREAVYVIYAFCRMI
                     DDSVDEPEQSTYTIHEIHDLFERLEEAEGHFIWPALRWLFSSFPHLDKGPFFRQMEGQL
                     SDLKKTHYDTMEELEHYCYLVAGTVGEMLLPVLRNDNGAEVAMNGIALGKGMQIVNIIR
                     DVGEDRARLRRYVPLEIMEKHGYSEQDWENGVVDERFVAIIHDMKSAALNWFRIGMDRL
                     DTYPVESAFSIELAAAFYSTILHAVERNDYDVYTKRAYVSDELKLEMLGAIVKRYPMLA
                     YQASRMAVS"
     gene            complement(10870..12333)
                     /gene="crtI"
                     /locus_tag="KZX51_RS12970"
                     /old_locus_tag="KZX51_12930"
     CDS             complement(10870..12333)
                     /EC_number="1.-.-.-"
                     /GO_function="GO:0016166 - phytoene dehydrogenase activity
                     [Evidence IEA]"
                     /GO_process="GO:0016117 - carotenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="crtI"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1222: dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017691907.1"
                     /locus_tag="KZX51_RS12970"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KZX51_12930"
                     /product="phytoene desaturase family protein"
                     /protein_id="WP_145404444.1"
                     /transl_table=11
                     /translation="MKRAAIVGAGIGGLTSALLLNRQGWDVTVYERGSRVGGRIAFEQE
                     GDYRIDQGPTIVLLPEMLLGILEEAGVDRSKIELLRCDPLYRVHYHSGRVMTKMTDRDQ
                     QTAEIERLFPGEGHGFNRFMKDMDTLFPAGRAAFLEQMFPRKRDFFTPSLMSLMGRLRA
                     HKSVRKAVGDYFEHEELLDAYSLQSLYIGGSPFGTPGIYSLLPYAEHEYGIWMVKGGYA
                     ALPAILEQELLSRGGRIKLQTEVTGLIIEGGVCTGIETADGAENVDAVIYNGDFPHVND
                     LLKQTPQAAGRRKAYRPSSGCVLVYAGVDKRWEDAVTHQFFLPPSLDGSLKEVFKQRRI
                     PAHPSFYVFNPVAVDDSAAPSGQSVLYFLIPVPDAEGVNWEEQSEALADRVLEEAEQRG
                     FPGLRAALQWKKVRTPADAARDGLYGGGSFGIAPVLFQSGVYRPQPKPFPQIRGLYAAG
                     ASVHPGGGVPIVMQGARMAVNQLMKEMGK"
     gene            complement(12330..13880)
                     /gene="crtI"
                     /locus_tag="KZX51_RS12975"
                     /old_locus_tag="KZX51_12935"
     CDS             complement(12330..13880)
                     /EC_number="1.-.-.-"
                     /GO_function="GO:0016166 - phytoene dehydrogenase activity
                     [Evidence IEA]"
                     /GO_process="GO:0016117 - carotenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="crtI"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1222: dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017691906.1"
                     /locus_tag="KZX51_RS12975"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KZX51_12935"
                     /product="phytoene desaturase family protein"
                     /protein_id="WP_145404445.1"
                     /transl_table=11
                     /translation="MIPNQQRKRAAVIGAGPGGLAAAMLLSGQGYEVDVYEKQPAIGGR
                     SSRLELGEYKFDRGATFLMMPQLIEEMFDVVGRKLSDYVDMKELTPLYALSFGDKVFKP
                     SRNREETAAQIKELFPGNEENYLRYMRDEEVKFGKVMPLLRRPFGKLTDYLRKDAITAL
                     PKLDINNTVYGILSRYFTDERLRWAFTFQSKYLGMSAWDCPGTFTILSFIEHQYGLFHP
                     IGGVNRVFQAMADVVEEYGGRIHTATPVKQVIVRNGRAEGVLLENGERIEADHVVVNAD
                     FAHAVNHLFEPGVLKKYTPEKMKRKKYSCSTAMLYLGVDGEIDLPHHSIYFPEDYRVNV
                     DEITKHKILSADPSLYVHNPSRLDPTLAPSGKSALYVLMPTPNLTGDIDWEAERSKVQE
                     AMLKRLEAIPELADIRGRIEECKLFTPLDWQNELDVYRGATFNMAHNLGQMMYLRPHNQ
                     FEELERVWLVGGGTHPGSGLPTIFESARISVRLIQEEDARRHTKPSSYVQTAEVGGHS"
     misc_feature    14024..14039
                     /note="TFBS match to RutR, Regulator of the pyrimidine and
                     purine metabolism, confidence: weak, score: 20.39"
                     /tool="antismash"
     gene            complement(14210..15121)
                     /locus_tag="KZX51_RS12980"
                     /old_locus_tag="KZX51_12940"
     CDS             complement(14210..15121)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017691905.1"
                     /locus_tag="KZX51_RS12980"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KZX51_12940"
                     /product="MerR family transcriptional regulator"
                     /protein_id="WP_145404446.1"
                     /transl_table=11
                     /translation="MYSIKQVAAMLGIQAVTLRAWENRYNAVTPERTESGYRMYTEEHV
                     ADLRWLKQQIDQHQTSISEAVRMLKEKKESRSKAVIPMPAAPPVPNAEEAYEHMTDQIY
                     DSLYHFQGERANGLIDFGFTMYGYDSMFYHVLVPILVRVGDAWEEGRATVAQEHFMTQL
                     ISQRFYQFFHLFPIYPHLPKVLAMCPEGEHHQVGLLLFSLFMRKNGAEVLYLGANTPED
                     GVFPIIREQKIKLVCLSITSSGLVDTCDRLIDRIREEFPHVRFVLGGKGFERAEHARYP
                     EWIMPEDSGDWQSWIEREYFTG"
     misc_feature    complement(15233..15248)
                     /note="TFBS match to CRP, Cyclic AMP receptor protein,
                     confidence: medium, score: 17.19"
                     /tool="antismash"
     gene            15324..16856
                     /locus_tag="KZX51_RS12985"
                     /old_locus_tag="KZX51_12945"
     CDS             15324..16856
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017691904.1"
                     /locus_tag="KZX51_RS12985"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KZX51_12945"
                     /product="phospholipase D family protein"
                     /protein_id="WP_145404447.1"
                     /transl_table=11
                     /translation="MVSSRRSISEQHSSQRKFPYIRTAIVLLILWLIAVMIYQTYKPLP
                     PGISYESSEYRVQNVQFLNDLTYPSSDGQMQHEQQIFQRMLQVVKDAEQFVVVDMFLYN
                     NYQHKGQHFPPVSQQFTDTLIAKKTNNPDMNIWFITDEVNTNYNAAPNPLLEQMKQAGI
                     HVVITNLDPLRDSTPVYSAVWRTFFQWFGQSGKGWIPNLMATDGPDVTLRSYLKLLNVK
                     ANHRKVVASEKTAIVSSGNIHDASAYHSNIGFEVTGPVIGDIIQAEQAVVDMSGGGQLP
                     VYDASAQTSSSSFSSDSSPFSEAAKESESEGPIRLRYLTEGKVNDALLYEINQTGKGDT
                     LWMGMFYIASPKVLEALLDASKRGTDIRLVLDPNENAFGQEKIGIPNRPVAAELHDKSS
                     GSIQVRWYNTTKEQYHTKMIYIAKATGDHIVIGGSTNFTPRNLNDYNLENDMWIAAPAD
                     AAFTIDVADYFKRIWVNEDATFTLNLEEFQENTTFLKGILYKLQLILGFTTF"
     misc_feature    17184..17202
                     /note="TFBS match to HgtR, Hydrogen-dependent regulator,
                     confidence: weak, score: 24.51"
                     /tool="antismash"
     gene            17305..17919
                     /locus_tag="KZX51_RS12990"
                     /old_locus_tag="KZX51_12950"
     CDS             17305..17919
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1057: TetR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017691903.1"
                     /locus_tag="KZX51_RS12990"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KZX51_12950"
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="WP_145404448.1"
                     /transl_table=11
                     /translation="MTAHSIRDAALYHFARDGYEGASLRAIADEVGIKKPSIYAHFSGK
                     EDLFMRTLEYAFDEVRRHTLEYFRDHTHLTLEERLRGLLTWFEQEYQDHASARLMLRNC
                     YYPPPDLYSQVMDLVYPFLDGMERALSRLLQRAIREGDVPPLPAEQAAIAFMTFLDGIT
                     VEIIYGSSRRYKRRMDAAWPVFWYGVRSLNEGALSAVPEGD"
     gene            17925..18281
                     /locus_tag="KZX51_RS12995"
                     /old_locus_tag="KZX51_12955"
     CDS             17925..18281
                     /GO_function="GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018670933.1"
                     /locus_tag="KZX51_RS12995"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KZX51_12955"
                     /product="multidrug efflux SMR transporter"
                     /protein_id="WP_145404449.1"
                     /transl_table=11
                     /translation="MNRNWLYVFIGGIIEIVWVSGLKHASNTWEWALTAAAIVISFALI
                     IAASKRLPVGTVYAVFTGIGTAGTVLTEMLLFGEPFRLAKILLIGLLLCGVVGLKLVTD
                     QQESKEPQVKGGAA"
     gene            18281..18595
                     /locus_tag="KZX51_RS13000"
                     /old_locus_tag="KZX51_12960"
     CDS             18281..18595
                     /GO_function="GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016822860.1"
                     /locus_tag="KZX51_RS13000"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KZX51_12960"
                     /product="multidrug efflux SMR transporter"
                     /protein_id="WP_111269038.1"
                     /transl_table=11
                     /translation="MAWLAIAGAGICEIFGVIGINGASSRKGWPYIVLMLVSFVFSFSL
                     LSYAMTAIPMGTAYAVWTGIGTVGSTVTGMLLFGERKEAKRLLFIAMILVAAVGLKLIT
                     "
     misc_feature    complement(18938..18952)
                     /note="TFBS match to IolR, Regulator of the inositol
                     catabolism, confidence: strong, score: 20.54"
                     /tool="antismash"
     misc_feature    complement(18939..18952)
                     /note="TFBS match to LexA_variant_2, Repressor of DNA
                     damage response, confidence: weak, score: 19.51"
                     /tool="antismash"
     misc_feature    complement(18980..18989)
                     /note="TFBS match to ToxT, Regulator of MSHA biosynthesis,
                     confidence: strong, score: 18.57"
                     /tool="antismash"
     misc_feature    complement(19801..19816)
                     /note="TFBS match to RutR, Regulator of the pyrimidine and
                     purine metabolism, confidence: weak, score: 20.23"
                     /tool="antismash"
     gene            19859..20806
                     /locus_tag="KZX51_RS13005"
                     /old_locus_tag="KZX51_12965"
     CDS             19859..20806
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1057: TetR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: protein motif:HMM:NF012655.4"
                     /locus_tag="KZX51_RS13005"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KZX51_12965"
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="WP_145404450.1"
                     /transl_table=11
                     /translation="MNPIHEMNEKRKLIITTALKLFSAKGSAATSMQEIAELCGMSKGS
                     LYLMFKSKEELEASTLEYCVYVLMDEMSQIEHETSLTSRERLHKQIEALLTHVAELKEF
                     LRVQMRSMMMDDEQQRKEKCTPQQRDIEIRTLHWFKSKLEDLYGPDIEPYTIDLIMLTH
                     GLFLSYVKIWFTEMPSLTVNKMASNLLQMMDYAAAGYLQQRPVPLFPLEQWPAWVAETQ
                     PDSAILRHPVHILKQMQDIASRELPAGQSRNDVLETIAILRQEIMEFSPRRAIILGMMR
                     NLEGIALLEPMHSELQHIMDTMYNRFIQADSSNT"
     misc_feature    complement(20829..20842)
                     /note="TFBS match to PsrA, Oleic acid responsive regulator,
                     confidence: weak, score: 19.95"
                     /tool="antismash"
ORIGIN
        1 tgtgtgaatg acacccgctg cgcctggtgc ttttgttcct ttacggatgg tccatgcacg
       61 aacctcttgt acacctgctg taaagtacgt gtacaggcca agcagcttgt aagccgcttt
      121 gatgagcagg ttcagaccgg attcctgaat acccagctct tccaggaaca tttgtttatc
      181 ttcgccttcc agctcggaga tttcttcctc aaccttcgcg ctgattggca ccacttctgc
      241 attttcagca gcagcgaact ctcttacttt ttgcacatat gcattgttcg ctacatcacc
      301 gatttcgtcc tcagccacgt tggcagcata cagaaccggc ttcagcgtaa gcaggtgcag
      361 atcacgtacg atcaggcgct cttcatccga cagctccatg ctgcgtgcag gcatatcttc
      421 ataaagaacc gctttgactt tctccaatac ttcaacttct tgagcagccg ttttgttgcc
      481 gcccttcatg tttttcttgg agcgttcgat ttttttctcc acactctcga tatcagccag
      541 aatcagctcc aggttaatcg tctggatgtc gctgatcgga tcgattttgc catcgacgtg
      601 ggtgatgttc tcatccacga agcagcgtac cacgtgtaca atcgcatcca cttcacggat
      661 gtgggcaagg aacttgttgc ccagaccttc acctttggaa gctccacgca ccagacctgc
      721 gatatctacg aattcaaatg cagttggcac tgtttttttc ggttcaacca gttctgtcaa
      781 tttgtccaaa cgctcgtccg gtacttcgac gatccccacg ttcgggtcaa tcgtacaaaa
      841 cggatagttc gcggactcgg cacctgcttg tgtaattgca ttaaacaatg tagatttacc
      901 aacgttcggc aaacctacga tcccagcttt caaagccatg tatatgacaa ctcctcattc
      961 attacttgtt cggtatggat aatcctaacc attatatatg acaaacccct aggcatcaag
     1021 gaacttcgcc gattcatcgg cagtcattct gatctgtaga tctccggttc ccgcgtccat
     1081 gtgagtatcc ccatcgggcc ataatgtttt aagtcgctca atcggcctga atgcatgatc
     1141 catttttata taggatttac aggattaaag cttagcgttt cagcccctgt tctcgatctc
     1201 tttatacatc gtcaaatccg tcacttcata acccattttg cgatacaggc tgcttgcccg
     1261 cacattatgt ccaaacacat gcagaccaat gcggtccacc ccaagacgac gcgctgtacg
     1321 ttcaagtgct tccattgcct cagtgccgta ccctttgccg cgatgtgctt cttccaccac
     1381 aatatccagc aaaaaggctt ctttcccgcg acgattttcc gtaacattaa accagatgta
     1441 cccgacaatg ccgtccaccg gatgcaccac attgtacacg tatgcccctg gcgtctccaa
     1501 accttccggc aaataacgct cataagagtc ctctgcccgt tcttgcgcct cctctggcgc
     1561 ccacgtgcct gcttccacct tttcctctgc aaaatctgca atcgaacgac tgtgaaaact
     1621 cgcaaattgc tccccgttca ttggcaacag ttccatgctg tattcctcct catctgggtg
     1681 tgatcactta ggtgtgatag gtatgtataa ttagacagct aattgatcct gatctattgt
     1741 accctaattg tactgtatcc tgtgatgatg taagttaggc acttctcttt tttccatgtc
     1801 tacttatgtt aaaatataag ggcgagcgac cggccaaagt ttctcgccca gaggtcgatg
     1861 ggttattcca tcggctttac ccttttaaca tgattatacc gattaatcag ctcgtccagc
     1921 accatggact ggtggatgac cttagggtga agaaggtcgc cgtactccgt ttttaatcga
     1981 tggagtttca ctcttgcttc ttcaattcgc agtttgagtt cgtcacgatc cataacaccc
     2041 ctccctgctt taccatttta gaacatcctg ctaattagta aaaattcaaa taatccccaa
     2101 cataggatcg caaaaaaaac accctttacc cgaaagacct ctgaacaatc tgtgacgatt
     2161 gtctattcaa aaagcatttc gaaagctgag gatgtatcca cgcgcaaact gcctctcttc
     2221 aactatgata acagcctgtc tatacttagg tggtgttata ctttaagttc tttacgattt
     2281 tttacgcttt aacatgtgga ctatataatc tctgaatttt ctcaataagc tgttctgcgc
     2341 ttggcttagc gccccgtccg gttgcatagt gctgcaaatc ctcaaataac cccaagcaat
     2401 ccagcagacc atccttattc atattttcaa ttgcaaattc catgccttta cggatatacc
     2461 ctacgcctct atcataatcg ttatttctta aatagtacgt acccagtcct gccagcaaaa
     2521 taccatattg atcattggtg tattgcttgc tcatttttcc caagcgactg ctctgttcct
     2581 cgtaaaccaa ataggactga tactcatcaa gaacagaatc aatattgata ttataccgat
     2641 tcgctgcggt cacaatcgcg catagtgcag ggaatacttc tttttttcga tcagagatat
     2701 actttaaata atcttgaatc aactctgtct cacctgacaa caatctaaaa tagtagttat
     2761 ttccttctga ccaatcctga aattgaagaa ttacgatttt ttcttcttcg gtaggatctt
     2821 tgatccagct gtagtcagcg tattttgaaa catattgaag cgtttcttca taatttccat
     2881 gttgataact gacctcggca agagcaaggt aagaatacaa agcataaaat acaatcttct
     2941 tcttggtttt agtctccact tctcttaatg ttttcttggc ctcatattga ataaaagctt
     3001 tgatctgtag ctgatcagca aactctttca ctttgtccca acggcgcaag gaagcgtaca
     3061 cattaattag atcgttcagt gcatcgaatt ggtaaggttc gtcaagacgt tgaacaaata
     3121 gctcgaattg tgtggctaat gtcagattgt tactctggtc attagaaagt ccgatggaaa
     3181 acaaacggta ctggcttaaa gccagacgct ccgaatgctg caatttctca ctctccgcaa
     3241 cacagcggta taaaggtatg cacgcctcca gcttcccctc gctatataac tgttcagcca
     3301 gctcaaacaa catgggaaca tacgagagat gatcagccac atatctgacc gcagtctcca
     3361 tataagagac atgacccaat tccgcacaac gatataaaaa gggcctcagt cttcgccaat
     3421 caagattggc atcaattaaa tattcgtgta tgtatagttc atataagtgg ccttcgggca
     3481 agcccattcc ggcagtaatc cgatccagct gattcaggcc tattggacga agtcctttca
     3541 atgtgccgct tagtgttccg gaattaacac ctgaaatctc cgaaaagcga tgtatggtca
     3601 ttcgattatt tttcaaataa cgttctaaat ggtcacatat tgtggctttt gaattcaaag
     3661 ggacaccgcc ttcccatgaa atgaagctcg atcaatgaaa tcatacaata tttatgtaat
     3721 tttcatcaat aattactttt gaattgttta ctataatata ccaaacaaaa acccgcccca
     3781 ttttagttgg ggcaggtctt tgtagaaaat tacaatccgt acgtttccat ctcgaattct
     3841 aacgattcct agagacgcta tttagcccat ttgagtcact ttgaaattct aacgatctcc
     3901 agaagcctta tttactccaa acaccccgat ttccaccgaa atttctgcgt ttttgcccaa
     3961 atagcgcttc tgtgaatcgt tagattttta aaagccgttt taagggtgaa ataaggttct
     4021 ctggattcgt tagcgctttt ggtagcatga tccaaccttt gtttctccac tcaagactcc
     4081 tcaacgttcg caatattcca ctgcttgcat tatgcttcgg caggccagct gcgcggcgcc
     4141 ctaccccagt catcttcatg ccccaatcgg caaggcgaca ccatcacaat acctcatctg
     4201 actcaaccaa cgttaccgcc gcgccaccag acgttctgtc tgcttcacat ctgcaatact
     4261 gcctgcaccg atgccaaaca taaccgtgcg cagctcgaat tcgacctgct ccagccgctc
     4321 ggatagtgct tcgtcggagg tgacggcgga ttcgagcagc gagcggccga agccggcaag
     4381 gtcggcaccc agagcgagcg ctttggcggc gtccacgccc gtgtgcagtc caccgctgcc
     4441 gatcagcgcc ccatctggat taagcgcgcg cacgtcctga atgcactcgg ctgtgggaat
     4501 gccccagtcg gcaaaagctt ccgctgccgc ccggcgtacc gggttattgt ttcggtactt
     4561 ctcaacctgt acccagcttg tcccacccgc gccagccaca tcgatgaatg ccacgcctgc
     4621 ttcgtacagg cgctgtgccg ttacaccatc gatgccaaaa ccaacctcct tgacgccgac
     4681 gggcacttcc agttcacggc acaggctctc gatccgctgg aacagaccgc tgaagttggt
     4741 attgccttcc ggctggaaca cctcctgcag cgtgttcaaa tgcagcacga gcagatccgc
     4801 gccagcgatc tccacggcac gctggaaatc agctgtgctg aagccatagt tcagctgaac
     4861 cgcgcccagg ttcgcgatga ccgggatgtc cggtgcccag cggcggacat cgaatgtgct
     4921 cgcgagctcc ggctgctcca cggcagcccg gatcgagcct accccgagcg cccagcctct
     4981 ggcgttcgct actcgtgcca ggcgctcatt gatagcgcca gtggtttggc ttccacccgt
     5041 catcgagctg atgagcaggg gtgtacgcat ttttttgcca agaaacgaag tgtccagaca
     5101 cacctcttca aagtccagct caggcagcgg gtgatgccga aatgcaaact tctccagccc
     5161 gctcgtaatg ccttctcctg ccacattctg ctccagacag aggcgcacgt gctccagctt
     5221 ccgttctccc gttgccactt cgggcagcag ccgtttgccg gctcgttctt gttcattcat
     5281 gatgagtcct cctatgtgag aatgatgtgt attggcagga atgacagcaa tttttgtttc
     5341 atatttcaag tttcgtgctt cacgtttcat gttgttccat gcttcatcgt ttcctgctgc
     5401 ctgccttatg gatacctgct ccgtatctct agttctatgt aaacaactct atccagtata
     5461 ccgttcctgt tcacctaatg aaaggatgct ccaaaacccc gcgatctcat caatgacctt
     5521 attggagtct cggagcagca gattacttca cttattggaa tctcgaagca cactggtcta
     5581 ccttactgga ctcctaggca ctctgctaac cagattggac ccctgaggtg ccccgcaatg
     5641 ccatacaaca atttcacagc atcctgatct gcctcatgga gtcccggagc acccatttct
     5701 tacggcatct actctacttg taactgcgca tgcacctgcc cgtctgctct tacctgccca
     5761 tctccgctgc aagctgctca cccacaagct gaccggataa cgtaacaatc ggggttccgc
     5821 cgccagggtg ggttgtgccg ccaacgtacc agagtccctg aacatcgctg ctctgattgc
     5881 ccggacgcat gaaagtctgc ttcattgaat tggatgaaat cccgtagatg gagccttgat
     5941 gagctaatgt atcacgtgcg atctgctgcg gtgtatatcg gatcaacaca tctgattgct
     6001 tcagcccgcc aatgccgcgt gactccagct gctccagcac aaactcgccg taacacttct
     6061 gctgctcctc ccatttccag gcgttcgaga gatatggcgc attcacaaga atgaacagat
     6121 tactcgctcc cgcaggagcc atgcctgatt cagaatatcc agagtaacag atatatatcg
     6181 ttggatcggc cggcatcatg cggtcacgaa aaatatgctc gaactccggc tcataccgct
     6241 ccgggaaaaa gacggtatga tgcagcagct gaccgtattg tctgcgcact ccggcaaggg
     6301 taacaaaacc ggagatggaa ggctcatact ttgcaatgcg ggcatcattc atacgtttcc
     6361 gatgctcggt tgcgagcagc agccggttca cactaagcac atcaccgttg gccacaattc
     6421 ggtcagcctc catccatccc cgatccgtat ccacgccaac gacctttccg ttccgaacga
     6481 caatctggtg cacctctata cccgtcataa tctgcacacc cttctccctt gcaagacggg
     6541 tcatgccttc gataagctga tacgttccgc cttttacccc gtagatgcct acttctgctt
     6601 caacatgacc catcattgca aaaatggagg gcgacagata cggcgatgat cctacatatg
     6661 tggcataccg cccaaacatc gcaagggtat gcggatggct gaaatacctg cgcagcagcg
     6721 tatccagctt gaccgcaggg cgcacccgga gcagactgcg cagcatttgc agattgtatt
     6781 tgtcggacgg tttcagcagc agcttaccaa gaaaatggcg attcgcctcc atatacaatg
     6841 acgcagattc atccataaac gcatcgtaac gcatggcatc ctgcggactg tatgcagcga
     6901 tctgctcctt catccagcca cgatctctcg acagatcaac gacagtgccg tctgcaaaca
     6961 cattccttgt ccgcggctcc agctcataca gctgcacgta atcctccatc cgcacgccag
     7021 cctgatcaaa caccgagcga aatgcatccg gcatcgtaat cgtgcttggg ccccggtcaa
     7081 agtgataccc gttctgctcg atttgctgca gcttgccacc cacatgctcc tgccgttcca
     7141 gcatcgttac acgcaaacca gccgaagcaa gacggatcgc acaggacagg cctccgaagc
     7201 ctgcaccgat aataatgacg tcctgttttg agttcccaac tgatgccgcc tctcggtgcc
     7261 cgttatgcat ttctactccc gatccttcat ctctcacatt tgcatttcca ttctcgttcc
     7321 cctgtgcatt gtgcatcagc tataccgcct gcctttccat acgtaccctt taccagatcg
     7381 tcccgcctgc catgaggcca gaccgatggc aatgacacaa gccatgctga tcggttgaaa
     7441 aagtgcgagc caccacggct gacctccgat atgatcggat actcgtttta cagccacgcc
     7501 aagcaacgtg cctataaatc cgtacagaat ggatgtctcg ttccccgtaa gcagtcctat
     7561 aaccagccct agcggcggca caatgtacat cataaaatac ataaacatcg taccaattaa
     7621 cagtgcatct ctccggccca tgccttcgta catgtttttt ttatacccgt tccatacctc
     7681 ttcaccgttc tgatacatac gtgtactcgt tacatcatgc acatccgcga gcaacacggg
     7741 atgcccggca cgtttgactg ctttggcaag actcatgtcg tccaccagat gtgcctgaat
     7801 ggcggcatga ccgccggatg cttcataact tgtgcgatgg ataagcaaaa aagcccccgt
     7861 agcggcaaca aacatcggac tggctgacct gcgtatcatg aaaataggca aatgactgat
     7921 gatcgtaaac atcatcattg gcacgaccag cttttccatc caggttcttg ccacctgata
     7981 ggggaacccc gtaaccagac cgccgccctg ggcacacccg gcagccacca tctgcctgat
     8041 tgcatccggc ttcacacgaa catcggcatc gacaaacata aaccattccc cctgcgcctc
     8101 ctgaaccaga cgatgacagg catgggattt gcccatccac cctgcaggaa ggtcggtccc
     8161 gtgcagcaat cgcacacgcg aatcccgatc agcaatcgcc tgaacgagtg aagcagtctc
     8221 atcttcagag cggtcgtcga gcaccaatac ttccatgaga aatcccttcg tatgactggc
     8281 aagcacactt tctagacatt cttcaatatg taagcgttca ttccttgcag gaatcagaac
     8341 ggagaccagc agatcgggtg gctgtatgct gcctctttgg aaagaacgta tttggggcag
     8401 acaggcggca ttccatattg caaacaacaa ttgcacgagc agccatccga ccagacacat
     8461 ccacagaatt tcagctgtac ccacaccttc attcatacta tcggttcacc cgccttcgtg
     8521 cctcatcgta tttttcactg gtagagcgtg tgccgcgaat caaggggtac gcgtccggca
     8581 gactcccttg cccaagtcgg atcaaagcag ccctgtgctc atccagctgt tgttccaata
     8641 ctcgccccag ccgctctgca atctcttcac tcttccacgc tctccaatct cccacgatag
     8701 gcgaacccgc ctgcatggag atttccggca aatcatgctg aaccatgcca tgacataacg
     8761 taactggcac ggcaacagcc tgcggaaaac ggcgcagcac aagtccaata cccgggcgaa
     8821 actgaatcgg ccgagcctcc tgatgcagaa tttcaccttg cgggaagatc cagacccttt
     8881 tgccagcagc cagcagctca ttcgtatatt gcaacgatgt ccgaacacca gatgaactgt
     8941 ccttgttgat ggaatacgcc ccgagcttgc gaaaaaaagc atattgccga agctgccgct
     9001 cttccatcat cacataatga tccccacgcg aggtttgctt cgccgcatga tacagcagca
     9061 atccgtccca ccatgagctg tggttcatga aataaactat cggctgatct ggtgccgtag
     9121 gcagcagcct gccgtttcca tcaggcacct gtggatcaag agagcccaaa agcgtaaacg
     9181 aacgaaaacg tctgcgcagc agataataat gattgtacag ggtgaatatc cgctcaaacg
     9241 ctttggattt tacggcgcgg atcatacaac cagctcccct cggcaagcag cacacctgca
     9301 atcgcgatga tgaagctgcc tgtgatgcct tccttcagcg ccagcacacc gaacaaaagg
     9361 atgaacagct gatacagcca tttcgctcgc aggagcgagc ggcgatcgtt aggcacagct
     9421 ggcaggaaga gcgaaagaaa tgcacccata atgaaccagc taatgtaatt cgtccatggt
     9481 actccataga atccgcctgg ggactgccat tcccagaacc ctctcgcatg agcaaccggg
     9541 tcaagtacca gatccagcac aatcgcccaa aagcctgtct tgagtgcacg taccagcttg
     9601 ccaccccagg tcgatccgcc accgctgatc agcgctgaat tgccaacaac ggcgatccat
     9661 gcgaacccaa gtgtcaccgg aacactgaac agatgcacgc caaagaagtc ggagtacgcg
     9721 tattcgccaa aaggccagtg ggtatgtaca ccgatccact ctacgcccat gcccccaagc
     9781 cagatgatca atgaagcaat ccagagatcg ggacgcagcc acttgactga ctggtcggac
     9841 agagcagatc ggttggatgg ctgatataca aggtcaagca cgtaaagtgc ataaaataca
     9901 aggaatagtc cgttagagaa ggataacacc tcgggaacac caatcgtaag catcaggatg
     9961 gctccaatgg tataccacac ccagtacacc cactggatca tcaggatacc gccattcggg
    10021 aagcttgata agccagcatc gggtaacgtt tcacaatcgc accgagcatc tccagtttca
    10081 attcgtcgct gacatacgcc cgtttcgtgt acacatcata gtcgttacgc tctacggcgt
    10141 gcagaatcgt ggaatagaat gctgccgcaa gctcgattga aaatgcactc tccaccggat
    10201 aggtgtccag acgatccatg ccgatgcgga accagttcag cgccgccgac ttcatatcat
    10261 ggataatcgc aacaaaccgc tcatccacca cgccgttctc ccaatcctgc tcggagtacc
    10321 cgtgcttctc cataatctcc agcggcacgt agcggcgtaa tcttgcccgg tcctcgccca
    10381 catcacgaat aatgttgacg atctgcatgc ctttaccgag tgctatcccg ttcatcgcca
    10441 cttctgcccc gttatcatta cgcagcacag gcagcagcat ctcgccgact gttccagcta
    10501 ccagataaca gtagtgctcc agctcctcca tcgtgtcgta atgggtcttc ttcaggtcac
    10561 ttaactggcc ttccatctga cggaaaaaag ggcctttgtc cagatgcggg aagctgctga
    10621 acaaccatct cagtgcaggc cagatgaaat gtccctctgc ctcctccaga cgctcaaaca
    10681 aatcatgaat ttcatgtatc gtatatgtcg attgctcggg ttcatccaca ctgtcgtcaa
    10741 tcatgcggca aaaggcatag atcacatata ccgcctcgcg gcgcggactt ggcagccctt
    10801 tgaaggcctg ataaaaagac gaggagccct tctgcatcaa ctcttcacat ctgctcaata
    10861 ttgcttcatt cattttccca tctccttcat gagttgattg acagccattc gtgcgccttg
    10921 cataacgata ggcacgccgc cacctggatg caccgatgca ccggcagcgt ataagcctct
    10981 gatctgcgga aacggcttgg gctgcggacg gtatacaccc gactgaaaca gcacaggtgc
    11041 aatgccaaag cttccaccgc catacagacc gtcacgcgct gcgtcagcag gggtccgtac
    11101 ctttttccac tgtaacgctg cacgaagtcc cgggaatccc cgctgctccg cctcctccag
    11161 cacacgatct gccagcgcct cgctctgctc ttcccagttc acgccttcag catccggcac
    11221 agggatgaga aaatacagca cactctgccc tgaaggagca gccgaatcat ccaccgcaac
    11281 cgggttgaac acatagaacg aaggatgtgc cggaatacgc cgctgcttga atacttcctt
    11341 gagacttcca tccagacttg gaggcaggaa aaactggtgt gtcaccgcat cctcccagcg
    11401 tttatctacc ccagcgtaga ccagcacaca accggaagaa ggacgatagg cctttcgtct
    11461 gccagctgct tgaggtgtct gcttcaatag atcgttcaca tgggggaaat ccccattata
    11521 gatcacagca tccacatttt ctgcgccatc tgccgtttct atacctgtgc acacgccacc
    11581 ttcgataatc aggccggtaa cttccgtctg cagcttgatt ctgccgccgc gcgagagcag
    11641 ctcctgttcc agaatagcgg gcaaagcggc ataaccgccc ttcaccatcc agatgccata
    11701 ctcgtgctcc gcatagggaa gcaaggaata gataccggga gtaccgaagg gtgatccgcc
    11761 gatatacagg ctttgcagcg aatacgcatc gagcagttct tcatgttcaa aataatcccc
    11821 taccgccttg cgcacacttt tgtgtgcccg cagtctgccc atgagggaca tgagcgaagg
    11881 ggtgaagaaa tcccttttgc gtggaaacat ctgttccaga aacgccgcgc gacctgcagg
    11941 aaacagggtg tccatatcct tcataaaccg gttgaatcca tggccctcgc cggggaacag
    12001 ccgttcaatc tctgccgttt gctgatcacg gtcggtcatc ttggtcatga ctcgtccgct
    12061 gtgatagtgc acccggtata aggggtcaca gcgcagaagc tcaatcttgg agcggtccac
    12121 acccgcctct tcgagaatgc ctaacagcat ctccggcagc agtacaatcg tcggaccctg
    12181 atcaatgcgg taatcgcctt cctgttcaaa agcaattcgt ccgcccacac gggaaccccg
    12241 ttcgtatacc gtaacatccc atccctgacg gttaagcagc agcgcggagg tcagcccgcc
    12301 aatccctgcc cccacaattg ccgcccgctt catgagtgcc ctccgacttc cgccgtctgc
    12361 acataggatg aaggcttggt atgtctgcgt gcatcctctt cctgaatgag tctgacactg
    12421 atgcgggccg attcaaaaat cgtcggtaaa ccgctgcccg gatgtgtacc tccacctacc
    12481 agccatacac gttccaattc ctcgaactgg ttatgcggcc tcaggtacat catctgaccc
    12541 agattatgag ccatgttgaa ggttgcaccg cggtatacat ccagctcatt ctgccaatcc
    12601 agcggcgtaa acagcttgca ttcttcaatg cggccacgga tatcagccag ctctggaatc
    12661 gcttcgagcc gcttcagcat cgcttcctgc actttcgatc gttcggcctc ccagtcaatg
    12721 tctcccgtga ggttcggggt tggcatcagc acataaagtg cagattttcc tgacggtgcg
    12781 agtgtcggat caagtctgga tgggttatga acatatagag acgggtctgc agacagtatt
    12841 ttgtgctttg taatctcgtc tacattaacc cggtaatcct ctggaaaata aatcgagtga
    12901 tgcggcaggt caatctcgcc atctacaccc agatagagca tggctgtgga gcaggaatat
    12961 tttttccgtt tcattttctc aggggtgtac ttcttcagta cgccaggttc aaacaaatgg
    13021 ttcactgcat gggcaaaatc ggcgttaaca acaacatgat cggcttcaat ccgttcgccg
    13081 ttctccagca gcacaccttc agcccggcca ttgcgaacga taacctgctt cacaggtgta
    13141 gcggtgtgaa tccgtccgcc atattcttca acgacatccg ccatggcctg gaatacacga
    13201 ttcacgccgc cgatcggatg aaacaatccg tattggtgct cgataaacga cagaatcgta
    13261 aacgtgcccg gacaatccca agcggacatg cccaaatatt tggactggaa tgtaaatgcc
    13321 cagcgcaggc gttcatcggt aaagtagcgg gaaagaatgc cgtaaaccgt attatttata
    13381 tcaagcttgg gtagtgcggt gatcgcatct ttgcgcaaat aatcggtcag cttgccaaac
    13441 ggacggcgga gcagcggcat cactttgcca aatttcactt cctcgtctcg catgtaccgt
    13501 agataattct cttcattacc aggaaaaagc tccttgatct gtgctgctgt ctcttcgcga
    13561 ttccgtgaag gcttgaatac cttgtctcca aagctcaaag cgtacagcgg ggtcagttcc
    13621 ttcatatcca cataatccga cagcttgcgt ccaaccacat cgaacatttc ttcaattaac
    13681 tgaggcatca tcagaaacgt agccccgcgg tcaaacttgt attcacccag ctccagacgg
    13741 gaagaacgtc ccccaatggc tggctgcttc tcgtaaacat cgacctcata tccctgacca
    13801 gacaataaca tggctgcggc aagcccgcct ggacctgcgc caatgacagc tgcacgcttg
    13861 cgttgttgat tcggtatcat gccactcacc tttctatgta ggggaacctc tagttctcaa
    13921 gcccctaacc tactattaaa ctgtgaagaa acacttcaat cggataaacc gaaaaacatt
    13981 atacaaatgt agtacaaata ttatacgaca agtaaaacat aaaatgaccg atgggtcaaa
    14041 ttaatgttct ttttcaatga ttacacagca aaaaacatcc cttgatcatt agatcaaagg
    14101 atgtccgcta tacatgaatc tattcttttc attttcgttt tatgttgaat gcgtgtagag
    14161 agtgtcccct gtctgttcgc cgggtgacag ctcgcggctg ttctgcaagc tatcctgtaa
    14221 aatactcgcg ttcaatccat gactgccagt ctcctgaatc ttcaggcata atccactccg
    14281 ggtatcgtgc atgctccgca cgttcgaacc ctttgccacc caggacaaat cgcacatgag
    14341 gaaactcctc gcgaatccgg tcgatcagcc gatcacaggt atccaccagt ccagagctgg
    14401 taatggacag acaaaccagc ttgatcttct gctcgcgaat aatcgggaac acaccgtcct
    14461 ccggtgtatt ggcgccaaga tacagcactt cagctccatt tttgcgcata aacaaagaaa
    14521 agagcagcaa accgacctga tggtgctccc cttccgggca catggccaga actttgggca
    14581 gatgcggata gatcgggaac agatggaaaa actgataaaa acgctgggag atcagctgcg
    14641 tcatgaaatg ctcctgtgct accgttgcac gcccttcctc ccatgcgtct ccgacccgga
    14701 ccaggatggg tacgagcaca tgatagaaca tgctgtcgta tccgtacatc gtgaatccaa
    14761 aatcaatcaa accgttggca cgctcgccct gaaaatgata aagagaatca taaatctgat
    14821 cggtcatatg ttcatatgcc tcttcagcat taggtactgg aggcgctgca ggcataggaa
    14881 taacagcttt agacctgctt tctttctttt ccttcaacat gcgtacggcc tcggagatgc
    14941 tggtctgatg ctgatcaatc tgctgcttca gccagcgcag gtcagcaaca tgctcttccg
    15001 tgtacatgcg gtaacccgac tctgtccgct caggggtgac tgcattatac cgattttccc
    15061 aagcccggag cgtgaccgcc tgaatgccaa gcatagcagc gacttgtttg atggagtaca
    15121 catgattacc tactttctct ccatgaacgt tctacaaaaa taatacactc attatacaca
    15181 acgactttgc acctgtcgat taacgcgctc catctcatcc tgctgcacct ctcgtgagca
    15241 ttcttacaca tctcctgcgt caacatcgtc atacgtgtgg taatatacgt cattcagcaa
    15301 gcaaagaagg gaggcatcca ccattggttt catcgcgccg cagcatctcg gagcagcatt
    15361 cttcacaacg caaattccct tacatacgaa cagctattgt gctgctcatt ctatggctca
    15421 ttgccgtgat gatctatcag acctacaagc cgctgccgcc aggtatttca tacgaaagtt
    15481 cggagtatcg ggtacagaac gtgcagtttc tgaacgatct gacctatcct tcctcggatg
    15541 ggcagatgca gcatgaacag cagattttcc agcgtatgct tcaggtcgtg aaggatgcgg
    15601 agcagtttgt cgtcgtagat atgtttctgt acaacaacta tcagcataag gggcagcatt
    15661 ttccaccagt cagccagcag ttcaccgata ccctcatcgc caaaaaaaca aacaatccgg
    15721 atatgaatat ctggttcatt accgatgaag tgaataccaa ctataacgct gcgcctaatc
    15781 cactgctgga gcagatgaaa caggcgggta tccatgtcgt catcacgaac cttgatccgc
    15841 tgcgcgattc tacaccggtg tattctgcgg tctggcgtac cttcttccaa tggttcggac
    15901 aatccgggaa aggctggatt ccaaatctga tggcaaccga tggcccggat gttacgctcc
    15961 gctcctatct taaactgctg aatgtgaagg ccaatcaccg caaagtggtt gccagcgaga
    16021 aaaccgccat cgtctcctca ggcaacattc acgatgccag cgcttatcat tccaacatcg
    16081 gtttcgaggt aaccggaccg gtcatcgggg atattattca agcggagcaa gccgttgtgg
    16141 atatgtctgg tgggggacag ctgcctgtat atgatgcttc agcgcagacc tcctcttcct
    16201 ctttctcttc tgactcctct ccattctccg aggcagcaaa ggaaagtgaa agtgaagggc
    16261 cgattcgtct gcgatatttg accgagggta aagtcaatga tgcgctgctc tatgagatca
    16321 atcagactgg caaaggcgat acgttatgga tgggcatgtt ctacatcgct tcacccaaag
    16381 tgctggaggc gttgctggat gcatcgaagc gaggcacaga cattcggctt gtgcttgatc
    16441 caaacgaaaa tgcgtttggt caagagaaga ttggcattcc caatcgccct gtagctgcgg
    16501 agctgcatga caaatccagt ggcagtattc aggttcgctg gtataacacc accaaggagc
    16561 agtaccatac caagatgatc tacattgcca aagcgactgg agatcatatc gtcataggcg
    16621 gttcaaccaa cttcactccc cggaatctga atgactacaa tctggagaat gatatgtgga
    16681 ttgccgcacc ggcagacgct gccttcacga ttgacgttgc tgattatttc aaacggatat
    16741 gggtgaacga ggatgcaacg tttacattga atctggagga gtttcaggag aacactactt
    16801 ttctgaaagg catcctgtac aaacttcagc ttattctagg ttttactaca ttttgagttg
    16861 tgcatttttg agcttagctt taatactcgc tttgagctgt gcattgttaa atgaagggtt
    16921 gtttcacgga cactccgatg acagaacaac ctgtctaaat tatttcagcc tcttatagtg
    16981 aattttgtat ataacatgta tcgacttcag aacacatcaa taacagtgac tttaggtcat
    17041 aacaataaca acaacttcag atcacaaaca gctacttcaa atcacaacag tagcagctac
    17101 ttctggtcaa aatattaata gcaacttcag gtcaaatcat taacaactcg tccaggtcaa
    17161 aacattaagc aaatacctta ttaaaaccgt atgtagtata catccgtctg ctttcttcaa
    17221 ttgcggcggg tgtatttttt atcttgacag aggatgaaat gtgtgaaaag atgttcccta
    17281 acgatcgtta ggaaggtgaa gacaatgact gctcattcca ttcgggatgc ggccctttat
    17341 cattttgcca gagacggcta tgaaggggct tcattaagag cgatagctga tgaggttgga
    17401 atcaagaaac cgtcgatata tgcgcatttc agcgggaaag aggacttgtt catgcgcacg
    17461 cttgagtatg catttgatga agtacggcgg cataccctgg agtatttccg cgaccatacc
    17521 cacctgacac tggaagagcg tctgcggggg ttactgacgt ggtttgagca ggagtatcag
    17581 gatcatgctt ctgccaggtt gatgctgcgt aactgttatt atccgccgcc tgatctgtac
    17641 agccaggtca tggatctggt gtatcctttt ctggacggca tggagcgtgc attgtcccgg
    17701 ctgttgcagc gagcgatccg cgaaggagat gttccgcctc ttcctgccga gcaggcagcg
    17761 attgcattta tgacctttct cgatggcatt acggtcgaga tcatatacgg aagctcgcgc
    17821 cgttacaagc gaagaatgga tgctgcatgg cctgtttttt ggtatggcgt aagaagtttg
    17881 aatgaagggg cactttctgc tgtgccagag ggagattgaa catcatgaat cgcaactggt
    17941 tatacgtttt tattggagga atcatcgaga ttgtctgggt cagcgggctc aaacatgcct
    18001 caaatacatg ggaatgggct ttgacagcag cagccattgt tatcagcttt gcgttaatca
    18061 tcgccgcttc caaaaggctg cccgttggta cggtctatgc tgtatttaca gggatcggga
    18121 ccgcaggaac ggtattgacc gagatgctgc tgtttggcga gccgtttcgt ctggctaaaa
    18181 tactgctgat tggactgctg ctctgcggtg tcgtcggatt aaagctcgtg acagatcaac
    18241 aggaaagcaa ggaaccacaa gttaaaggag gtgccgcata atggcttggc tcgcgattgc
    18301 tggcgcagga atctgtgaaa tttttggcgt catcggtatt aacggggctt cttctcgcaa
    18361 agggtggcca tacatcgttc tgatgctcgt atcctttgta ttcagcttct cgctgttatc
    18421 ctacgctatg acagccattc ctatgggcac agcctatgct gtatggacgg gaatcggtac
    18481 ggtgggaagc acggtgacag gcatgctgct gttcggtgaa cggaaggaag caaagcgact
    18541 gctgtttatc gccatgattt tggtggccgc tgtcggattg aagctgatta cgtaacagaa
    18601 aagcatgaaa ccaaacgatg gaaatctgaa ccactctcgg cggttttggt ggttttggtg
    18661 gttttggcgt tttttgtatg ctaacgattc cagggaacgc tatttgggtg atatgacacg
    18721 tttttaattt ctaacgattc caggagacct tatttgagag atccgtcaat aaaatcggtc
    18781 ctttttcttg ttttatagcg aaataaggtt tctgggaatc gttacatttt cagatggctc
    18841 taaatcatca atataagctc atctgaattc gttagaatat ctgggtgtgt gagaaataat
    18901 cttaaatact caagcacaac cactctgaat tctcggccgg aacatatctt ctatggtata
    18961 agtacatcat tttatgcctt caaaaaacac aatctcttcg cattcaaaca caaaacttta
    19021 tgcatccatg caacacaaac ggatatacat tcaagcaaaa ctttatgcat ccactcaata
    19081 caaacggtat acattcaagc aaaacttcaa gcccagcgct atacaatcgg tcaagcaaac
    19141 caatctaaat tttcaattac aacctctata aatcctcaac gtataccgac gccctcctca
    19201 tagattaagt cgcagtttgc gcactgcgtg cagctcccag cacgctgttg tggctgacca
    19261 ccctcgtcat gaagcaggag ttacagcggg aaggaaagtt acagtgttag gctaagtcac
    19321 aacataagga tgaagtaaca atcggacagt gtgacttgtg agaaagaaca tgagtagcta
    19381 ttcacatgag attaggacaa tgagagagtt atacagtatg ttacacagta agttacactc
    19441 taagttgtac agcaagttat acataaaagt gagtaaataa aacacatgat aaataagctc
    19501 gcctgataaa ctgtgccaga gttccagttc ctcccaacca atatcaaagg gcccatgtag
    19561 tcgagccttg cccctgatct attcgcctgt cctatctatt cccctagctc ttcaataaca
    19621 acccaagtac aagatacagc ttattcacag cctgtagaat gtactttctt gctattttca
    19681 tgctaggttt gcgaatgaga gcgcatggat actaattgtc ttcacctgca tctttccccg
    19741 catcagcccc tcaaaacata gagaatttgt aatctgttat tcacatcgtt tatactagtt
    19801 ttgaccacga agtcaattca agaactcaag agttcccaat gaggtgaatg tacccttaat
    19861 gaacccaatt catgagatga acgaaaagag aaagctgatc atcaccacag cgctcaagct
    19921 gttttctgcc aagggcagtg ccgctacctc catgcaggaa attgccgagt tatgcgggat
    19981 gtccaaaggc agcttgtatc tgatgttcaa atccaaggag gagctggagg ccagtacgct
    20041 ggagtattgt gtgtacgtac tgatggacga gatgtcccag atcgagcacg agaccagtct
    20101 gacctctcga gagcggctgc acaagcagat tgaagcgttg ctgacacatg tcgccgaatt
    20161 aaaggaattt ttacgtgtgc agatgcggag catgatgatg gatgatgagc agcagcgcaa
    20221 ggaaaaatgc actcctcagc aaagagatat cgagattcgc acactgcatt ggttcaaaag
    20281 caaactggag gacttgtacg gcccagatat tgagccttat accattgatc tcattatgct
    20341 gacgcatggg cttttcctgt cttatgtgaa aatctggttt accgagatgc cttcactgac
    20401 agtgaacaag atggcatcca acctcctgca gatgatggat tatgcagcag caggttatct
    20461 ccagcagcgt cccgtaccgt tatttccgct tgagcagtgg ccagcatggg ttgcggaaac
    20521 tcagccggac tcagcgatac tgcgccatcc cgtccatatt ttgaagcaga tgcaggacat
    20581 cgcatcccgg gagcttcccg cgggacaatc aaggaatgat gtccttgaga ccattgccat
    20641 actaagacaa gagattatgg agttttcccc gagacgagcc atcattctgg gtatgatgcg
    20701 caatctggaa gggatcgcgc tgcttgaacc tatgcactcc gagcttcagc acattatgga
    20761 taccatgtat aaccggttta tccaggctga ctcgtcaaac acataaacag gagacacaga
    20821 gaggagaaga aaccaacgta tgaaaggcat tattaacttt tcactgaaca aca
//
