LOCUS       NZ_CP096019            23138 bp    DNA     circular CON 29-JUL-2024
DEFINITION  Halocatena salina strain AD-1 chromosome, complete genome.
ACCESSION   NZ_CP096019
VERSION     NZ_CP096019.1
KEYWORDS    RefSeq.
SOURCE      Halocatena salina
  ORGANISM  Halocatena salina
            Archaea; Euryarchaeota; Stenosarchaea group; Halobacteria;
            Halobacteriales; Haloarculaceae; Halocatena.
REFERENCE   1  (bases 1 to 2527185)
  AUTHORS   Cui,H.-L.
  TITLE     Halocatena sp. nov., isolated from a salt lake
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 2527185)
  AUTHORS   Cui,H.-L.
  TITLE     Direct Submission
  JOURNAL   Submitted (18-APR-2022) School of Food and Biological Engineering,
            Jiangsu University, 301 Xuefu Road, Zhenjiang, Jiangsu 212013, China
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: HGAP v. 4
            Genome Representation             :: Full
            Expected Final Version            :: No
            Genome Coverage                   :: 477.0x
            Sequencing Technology             :: PacBio
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_023115355.1-RS_2024_07_29
            Annotation Date                   :: 07/29/2024 05:02:11
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,906
            CDSs (total)                      :: 3,855
            Genes (coding)                    :: 3,749
            CDSs (with protein)               :: 3,749
            Genes (RNA)                       :: 51
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 46
            ncRNAs                            :: 2
            Pseudo Genes (total)              :: 106
            CDSs (without protein)            :: 106
            Pseudo Genes (ambiguous residues) :: 0 of 106
            Pseudo Genes (frameshifted)       :: 56 of 106
            Pseudo Genes (incomplete)         :: 70 of 106
            Pseudo Genes (internal stop)      :: 28 of 106
            Pseudo Genes (multiple problems)  :: 39 of 106
            CRISPR Arrays                     :: 10
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 13:29:52
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 1441976
            Orig. end                         :: 1465114
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP096019.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..23138
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="lanthipeptide-class-ii"
                     /region_number="5"
                     /rules="cds(LANC_like and DUF4135)"
                     /tool="antismash"
     cand_cluster    1..23138
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="cds(LANC_like and DUF4135)"
                     /kind="single"
                     /product="lanthipeptide-class-ii"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..23138
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:13138](+)"
                     /cutoff="20000"
                     /detection_rule="cds(LANC_like and DUF4135)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-ii"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..13138
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="cds(LANC_like and DUF4135)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-ii"
                     /protocluster_number="1"
     gene            complement(168..695)
                     /db_xref="GeneID:71927859"
                     /gene="msrA"
                     /locus_tag="MW046_RS07390"
                     /old_locus_tag="MW046_07390"
     CDS             complement(168..695)
                     /EC_number="1.8.4.11"
                     /GO_function="GO:0008113 - peptide-methionine (S)-S-oxide
                     reductase activity [Evidence IEA]"
                     /GO_function="GO:0033744 -
                     L-methionine:thioredoxin-disulfide S-oxidoreductase
                     activity [Evidence IEA]"
                     /GO_process="GO:0006979 - response to oxidative stress
                     [Evidence IEA]"
                     /GO_process="GO:0030091 - protein repair [Evidence IEA]"
                     /codon_start=1
                     /db_xref="GeneID:71927859"
                     /gene="msrA"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020222471.1"
                     /locus_tag="MW046_RS07390"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MW046_07390"
                     /product="peptide-methionine (S)-S-oxide reductase MsrA"
                     /protein_id="WP_247992492.1"
                     /transl_table=11
                     /translation="MTDDATFGGGCFWCTEAAMKVLDGVESVTSGYAGGHVDDPTYEAV
                     CSGETGHAEVVQVEYDPSVRSYDELLEAFFRTHDPTQRNRQGPDVGTQYRSIVLYHDEQ
                     QRTTASAYIDALDAEYDDDVVTELEPLEQFWPAEEYHQDYFEKNPTDAYCQAHAQPKVE
                     KVRRQFETNVQH"
     gene            complement(740..1585)
                     /db_xref="GeneID:71927860"
                     /locus_tag="MW046_RS07395"
                     /old_locus_tag="MW046_07395"
     CDS             complement(740..1585)
                     /codon_start=1
                     /db_xref="GeneID:71927860"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1039: aldo/keto reductase family oxidoreductase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009377765.1"
                     /locus_tag="MW046_RS07395"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MW046_07395"
                     /product="aldo/keto reductase"
                     /protein_id="WP_247992493.1"
                     /transl_table=11
                     /translation="MADTTPTTFDIGGELTVNRLGFGAMRLTGEAIIGPPTDENAAKAV
                     LRRAIDLGIDLIDTADSYGPGVSERLIRETLHPFPEELVIATKGGLLRNRDGDWRPCGD
                     PDYLRNAVLCSRDRLGVETIDLYQYHRPDPEVPFEDSITALAELRDDGVIDHLGLSNVT
                     VEQIDRARDITEIATVQNKYNVTTRDDEDVLEACEEADIGFIPWAPMDAGSIGENADAL
                     RTVADEHDATPQQIALAWLLHHSPVILPIPGTASVDHLEENVAAAEIDLTDAQLRQLRE
                     "
     gene            complement(1644..2426)
                     /db_xref="GeneID:71927861"
                     /locus_tag="MW046_RS07400"
                     /old_locus_tag="MW046_07400"
     CDS             complement(1644..2426)
                     /codon_start=1
                     /db_xref="GeneID:71927861"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="MW046_RS07400"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="MW046_07400"
                     /product="hypothetical protein"
                     /protein_id="WP_247992494.1"
                     /transl_table=11
                     /translation="MTVPSSESDSLLTDRGRALCDRLTEELYTTDDSPYAEWKQLTALH
                     GFGWSVGSGNRVAGRLPARLDGEPIVRGPHDYVLKIEFDVNPDTPRTEMGNWVEAMIWE
                     QAEERGVSGLFAPVIDHAEDYRWLVMEEVETIGYDYPERAVDHSQTRQQEEYERRVSTF
                     EKRLDDAGLGLGLDGAGQIGVSRSGSIVALDYEHVTDESDVDQPAWIGSYNRYRGERLT
                     AEDVAQLGSRRERLRRITTGANGSVTGYEIRARLNEWR"
     CDS             2741..2938
                     /gene="allorf_1444717_1444914"
                     /locus_tag="allorf_1444717_1444914"
                     /protein_id="allorf_1444717_1444914"
                     /tool="antismash"
                     /transl_table=1
                     /translation="MIGSRGSTMSVINRISDAFFDKEHDQGPYACQSCDRRFSLQYQVC
                     PECGGYAIERVDWSEHIQNK"
     CDS_motif       2741..2830
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence: MIGSRGSTMSVINRISDAFFDKEHDQGPYA"
                     /locus_tag="allorf_1444717_1444914_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       2831..2938
                     /prepeptide="core"
                     /locus_tag="allorf_1444717_1444914_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class II"
                     /score="-4.20"
                     /molecular_weight="4095.5"
                     /monoisotopic_mass="4092.9"
                     /core_sequence="CQSCDRRFSLQYQVCPECGGYAIERVDWSEHIQNK"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MIGSRGSTMSVINRISDAFFDKEHDQGPYA"
                     /leader_location="[2740:2830](+)"
     gene            3036..3197
                     /db_xref="GeneID:71927862"
                     /locus_tag="MW046_RS07405"
                     /old_locus_tag="MW046_07405"
     CDS             3036..3197
                     /codon_start=1
                     /db_xref="GeneID:71927862"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006064735.1"
                     /locus_tag="MW046_RS07405"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MW046_07405"
                     /product="hypothetical protein"
                     /protein_id="WP_247992495.1"
                     /transl_table=11
                     /translation="MVEEPMLKGMPRCLNCGFEAPHDGGEWNSAQVPPLGDLMRCPECG
                     STNILGRW"
     CDS_motif       3036..3065
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence: MVEEPMLKGM"
                     /locus_tag="MW046_RS07405_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       3066..3197
                     /prepeptide="core"
                     /locus_tag="MW046_RS07405_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class II"
                     /score="-5.00"
                     /molecular_weight="4631.2"
                     /monoisotopic_mass="4628.1"
                     /core_sequence="PRCLNCGFEAPHDGGEWNSAQVPPLGDLMRCPECGSTNILGRW
                     "
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MVEEPMLKGM"
                     /leader_location="[3035:3065](+)"
     gene            complement(3318..4061)
                     /db_xref="GeneID:71927863"
                     /locus_tag="MW046_RS07410"
                     /old_locus_tag="MW046_07410"
     CDS             complement(3318..4061)
                     /codon_start=1
                     /db_xref="GeneID:71927863"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010903677.1"
                     /locus_tag="MW046_RS07410"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MW046_07410"
                     /product="DNA polymerase sliding clamp"
                     /protein_id="WP_247992496.1"
                     /transl_table=11
                     /translation="MFTAIVSSGTLLAALDSVSVLVDECKIRLDEEGATIRAVDPANAG
                     MVNLRLDTSAFESYETDGETIGVNLTRLEDIAGMANADDLIHLELDETTRKLHIQIDGL
                     EYTLALIDPDSIRQEPDLPDLDLSATIGIEGRDIDRAVTAADMVSDHIALGVDADEEYF
                     YVDAEGDTDDVHFELDRDELIMLSAGDAHSLFSLDYLKEMNKAIPNDAEVSVELGEEFP
                     VNLHFDIAAGDGSVTFVLAPRIQGN"
     gene            complement(4181..5155)
                     /db_xref="GeneID:71927864"
                     /locus_tag="MW046_RS07415"
                     /old_locus_tag="MW046_07415"
     CDS             complement(4181..5155)
                     /GO_function="GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /codon_start=1
                     /db_xref="GeneID:71927864"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1010: NAD-dependent epimerase/dehydratase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014039840.1"
                     /locus_tag="MW046_RS07415"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MW046_07415"
                     /product="NAD-dependent epimerase/dehydratase family
                     protein"
                     /protein_id="WP_247994741.1"
                     /transl_table=11
                     /translation="MDTALIIGGTRFIGRHTVREFRNHGYDVAIFNRGRHDSSFARDDV
                     VHVTGDRMDDDALDRARRQIDPDVVADCVAYHPANVQSATEIFADTDAYVYVSSGAAYG
                     TEVIPKREEETPLCACSPEQATDDSWETYGPRKADGDRAVFAAGDRGVRAMSVRPPIVY
                     GPHDYTDRFAYWIDRVHAYDRIIVPHSALRHLVYVGDVASAIRTIAERGDAGTAYNVGT
                     HTLPVLTEWIELIADALGTSAEPIEMSERELATTPLDPSDFPLYRDYPHVLDTHKLESI
                     GWEATPIPETVTTTVDHVVSTVQTVERGPDRAEERSVLETISS"
     gene            5233..5907
                     /db_xref="GeneID:71927865"
                     /locus_tag="MW046_RS07420"
                     /old_locus_tag="MW046_07420"
     CDS             5233..5907
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0008817 - corrinoid adenosyltransferase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /db_xref="GeneID:71927865"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006431390.1"
                     /locus_tag="MW046_RS07420"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MW046_07420"
                     /product="cob(I)yrinic acid a,c-diamide
                     adenosyltransferase"
                     /protein_id="WP_247992497.1"
                     /transl_table=11
                     /translation="MADDPASHTPGKGKTPTAQPIEAGSPEAFGFVQAWWGDGKGKTTA
                     ALGMGLRAVGHGYRVHLLQFMKGGASSVESVRGEYNAIATLPGFSYENLGHYGWHALND
                     GTDDHDHEKKAIAGYERATQLIEAIHEANLTEPLELDAPPEQGVHMLVLDELLYATERG
                     LIPPTDVVDLIETKPDDLELVLTGGHERPEFLEAHADLITHVDKDIHPFDSGQRSRQGT
                     EY"
     gene            6083..7591
                     /db_xref="GeneID:71927866"
                     /locus_tag="MW046_RS07425"
                     /old_locus_tag="MW046_07425"
     CDS             6083..7591
                     /GO_function="GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /GO_process="GO:0009236 - cobalamin biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /db_xref="GeneID:71927866"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015762810.1"
                     /locus_tag="MW046_RS07425"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MW046_07425"
                     /product="cobyric acid synthase"
                     /protein_id="WP_247992498.1"
                     /transl_table=11
                     /translation="MTHTLLVAGTASHVGKTTVVAGLCRLFASLDTPVAPYKAQNMSNN
                     ARVVPTPSGETGEIGVSQYIQARAGDVHPTTDVNPVLLKPRGDGDSQVVINGQAVGHYE
                     AREYYAEHWDRARSMARASWERLAEEYEYVIAEGAGSIAEINLHHRDLANVETARFADA
                     DILLVGDIERGGVFGSLLGTLSLLPDDLRARVVGCLITKFRGDRSLLTPGIEAFERRTG
                     VPVLGVLPYDDPGLPEEDSVALPPETERATIGGDDGVPETESVTIAVPRLPRISNFTDL
                     TPLERTPGVRVMYLPLSAGKQLTDADAVVVPGTKNTVDDCLALRSNGFDASLRAFDGPI
                     VGICGGYQLLGERLTNAAVEATGSVDVVEGVGVLPTETRFSTEKHVEPVSRTIHGCGPL
                     DGATGTVTGYEIHMGETKLLSPVDQPFDGTGAATDRVLGTYVHGLFENRPVREAFLDSV
                     FAHAGLVRPEADESARRVDLEAAYDRAADLIREHVDLEPLGLPT"
     gene            complement(7617..8363)
                     /db_xref="GeneID:71927867"
                     /locus_tag="MW046_RS07430"
                     /old_locus_tag="MW046_07430"
     CDS             complement(7617..8363)
                     /EC_number="2.3.1.-"
                     /GO_function="GO:0016747 - acyltransferase activity,
                     transferring groups other than amino-acyl groups [Evidence
                     IEA]"
                     /codon_start=1
                     /db_xref="GeneID:71927867"
                     /inference="COORDINATES: protein motif:HMM:NF025054.4"
                     /locus_tag="MW046_RS07430"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MW046_07430"
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="WP_247992499.1"
                     /transl_table=11
                     /translation="MNVRNATEADATRIYDIARQSIQASYAVSPTAIDVIIEEWFGVET
                     IEDRLDESVIGVAETDDSVVGFAEGTLADDTGELRWLHVHPEERGQKAGTELFEWMRET
                     LHDRGATAVHVRILASNSEGDSFAERFGYERIDQQDTEFGGDDWREHIYAPTAKEAEET
                     DPAEPQNVPSTIDAEGDERFVADDTIPGDAAPFHPVYNDDTYDEQYGFYCSNCGSAVEA
                     ADELDRIKCTECGNVHRPDDWDGAYL"
     gene            complement(8420..9253)
                     /db_xref="GeneID:71927868"
                     /locus_tag="MW046_RS07435"
                     /old_locus_tag="MW046_07435"
     CDS             complement(8420..9253)
                     /codon_start=1
                     /db_xref="GeneID:71927868"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006665092.1"
                     /locus_tag="MW046_RS07435"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MW046_07435"
                     /product="phosphosulfolactate synthase"
                     /protein_id="WP_247992500.1"
                     /transl_table=11
                     /translation="MPVDNRAFEFLRVNDRPDKPREKGITEIRGPYYDPMGPRELRDIL
                     ETMGHYVDIYKFSGGSFALMPEEAVVELIETCHEFDVEVSTGGFIEHVLVADNAHVEDY
                     VAKAGELGFDIVEISSGFLAIDVDDVVALTELVVDHGLKAKPEINVQFGAGGASSEEEL
                     LEETQQDPALAIEEGRRHLDAGAYKLMVEAEGITENVTDWRTDVAYQIATELGLENCVF
                     EAPGPEMFEWYIKNFGPNVNMFIDNSQIVECECLRSGLWGKKSTWGRVTSYDREE"
     CDS             complement(9289..9507)
                     /gene="allorf_1451265_1451483"
                     /locus_tag="allorf_1451265_1451483"
                     /protein_id="allorf_1451265_1451483"
                     /tool="antismash"
                     /transl_table=1
                     /translation="MRVIGFSSMGSRITLSDVRRGSLWFSLSATSNTSPFSSSNNVERL
                     RIVCGLCLPRRFRSSYAEEVSCLRTPG"
     CDS_motif       complement(9358..9507)
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence:
                     MRVIGFSSMGSRITLSDVRRGSLWFSLSATSNTSPFSSSNNVERLRIVCG"
                     /locus_tag="allorf_1451265_1451483_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       complement(9289..9357)
                     /prepeptide="core"
                     /locus_tag="allorf_1451265_1451483_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class II"
                     /score="-6.80"
                     /molecular_weight="2468.8"
                     /monoisotopic_mass="2467.3"
                     /core_sequence="LCLPRRFRSSYAEEVSCLRTPG"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MRVIGFSSMGSRITLSDVRRGSLWFSLSATSNTSPFSSSNN
                     VERLRIVCG"
                     /leader_location="[9357:9507](-)"
                     /alternative_weights="2486.9"
                     /alternative_weights="2504.9"
     gene            complement(9520..9666)
                     /db_xref="GeneID:71927869"
                     /locus_tag="MW046_RS07440"
                     /old_locus_tag="MW046_07440"
     CDS             complement(9520..9666)
                     /codon_start=1
                     /db_xref="GeneID:71927869"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="MW046_RS07440"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="MW046_07440"
                     /product="hypothetical protein"
                     /protein_id="WP_247992501.1"
                     /transl_table=11
                     /translation="MSVAIDTEVDVDKDAYDEQFDDNHTVHDQKVSTCTYLPNGVGMCH
                     TCG"
     gene            10001..13138
                     /db_xref="GeneID:71927870"
                     /locus_tag="MW046_RS07445"
                     /old_locus_tag="MW046_07445"
     CDS             10001..13138
                     /codon_start=1
                     /db_xref="GeneID:71927870"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-ii: DUF4135"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-ii: LANC_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1070: lanthionine synthetase C family protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004057361.1"
                     /locus_tag="MW046_RS07445"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MW046_07445"
                     /product="type 2 lanthipeptide synthetase LanM family
                     protein"
                     /protein_id="WP_368411313.1"
                     /sec_met_domain="DUF4135 (E-value: 3.6e-77, bitscore:
                     257.3, seeds: 79, tool: rule-based-clusters)"
                     /sec_met_domain="LANC_like (E-value: 7.1e-57, bitscore:
                     190.0, seeds: 47, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MVEHLSSEDRRTIAGRARTIHERLNGPSNEPGGEPPIDPDEIVAE
                     WTELFPDEESFTERLEHEGLTEAAVYEQLSATRWPEETPTPEWIDELESLIDHIKQFDP
                     DGRRAISSEIPFVDLLIAVADYGWAQLADEIRPPNGVPKLEEWLLARLGRLCVRALYVE
                     FKAFIEYHDPELAATDPEDVAEPGTAYYDRFIEAMFDDGFRKLCLEYPVLARFIVRQIE
                     QWVTTVTAICRRLRADRGMLDDRFAIDGEITAIDPLADDAHAGGQVPVRVSFESGSVIY
                     KPRSVDAGRLLYTVLDRLGSHLSTLEMTAPTYLSRDGYGWMETIDYREPSDTAAVDSYY
                     KRVGMLLCVAYVLDLPDCQFENLMVSGDQPTIVDAETIFHPYIDPVAAAYTTEVDAAIS
                     DSILRTGLLPWAIGDIGDEDNDLKKPLLAAGVGSSSETIEVSEISKPTVTAVNTDVMTI
                     TGEAPTVDRTTNTLSKDGTDHPPEEHIDTIVDGFQRTYDVIRELHENGRFRSEIVDPEL
                     IAGVENRLVFRSTDIYYSILRLSVARDPLRDGGRLSVEFERLAAWFFNDRIESDRYWGL
                     YDAERRSLRQRDVPRFTGRPGGTALYHDGTPTGLDADLSGYERCQQRLDAMGSADLQTQ
                     TWLIRRCIDDSFPARETPSSPLELTDERLQEEAIRYGDQVIDAAMETTVGHRWVSFIGG
                     ELPQLCVSPADNTLYDGRGGIGLAAAAIYDRTGHDRFRDVAIEALDLVAADHGESPTEF
                     GGIKGTGSIVYTLSVAASLLDRPEYRDRAAEYARAMTSTQLEGRPFDLVDGTAGMLLAL
                     LAHYERYGGTAIRDRAIDCGQRLLDGRVSVDGHRVWTTNDGDAMAGFAHGVSGIAYALA
                     RLAAVVGDDRYGSAAREALAYESTLYVPKRSNYAISSEPDRFQDQWCHGRTGCALARLG
                     IGVQLGDDELVTEANELLSATVEAEFSQYDQLCCGNLGRTVTLLEAARHTDRAETDARV
                     IAGQCLAREQQTGALSMLGNGEPVHNPTFFHGSSGAAYTILRLRDPEALPCVLLLE"
     gene            13143..13799
                     /db_xref="GeneID:71927871"
                     /locus_tag="MW046_RS07450"
                     /old_locus_tag="MW046_07450"
     CDS             13143..13799
                     /codon_start=1
                     /db_xref="GeneID:71927871"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007538896.1"
                     /locus_tag="MW046_RS07450"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MW046_07450"
                     /product="hypothetical protein"
                     /protein_id="WP_247992503.1"
                     /transl_table=11
                     /translation="MTEQLKIIFEVASAAGEERLIREYISPAFSRLEQRDDAHWPMFNR
                     YAQDPSVETGEVVLIVFGAVESIVGDERPRWIDLVDDGVLLDWQLETTGVETDTLDEQE
                     RFRYRLRTAASRMSLEFFGTFDPLPESVHELDTEGRSIGWELCLHHIINQLGYQANCGE
                     EEIDLLFRGLVSRLYAMAIAPEYGPEFAENKIEELTTELESLPPELQRFQDAHQP"
     gene            complement(13840..15198)
                     /db_xref="GeneID:71927872"
                     /locus_tag="MW046_RS07455"
                     /old_locus_tag="MW046_07455"
     CDS             complement(13840..15198)
                     /codon_start=1
                     /db_xref="GeneID:71927872"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007690138.1"
                     /locus_tag="MW046_RS07455"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MW046_07455"
                     /product="MmgE/PrpD family protein"
                     /protein_id="WP_247992504.1"
                     /transl_table=11
                     /translation="MTTTAELADFALSVSYEELSEDVCEELKKRVLDSIGIAVGALGAD
                     ATDSVRATCTELESDGPCRLWGSDRTASPVGAAMYNTALTRYLDYMDSFLAPGETPHPS
                     DNIGSVIACAEAGDRTGRELLAGIGVAYEVQGELAWNAPVRDRGYDHVTHTVVSAATGA
                     GVVRGLDREQLRNAIGIAGTAHNALRVTRTGGINEWKGIASANAARNAVYSVMLADHGM
                     EGPTNLFEGQKGWKQIISGEFDVSLDSNCERVFDTMTKRYVAETYAQSAVEAIIELAEI
                     HDIDPETVESIHLDTFAGAKLIIGGGEGSRYEVESKAQADHSLPYMLAAALIDRQLTND
                     AYDPERINRDDVQTLLRTVTVEEDEEFTERFERGEMPARVTVEFDDGTTHRAETDDFSG
                     HPNNPMSWNQIEDKFTTMTDDRYDRSRQQEIIDTVRTLDEHDVDDLTRLLDVS"
     gene            complement(15285..15725)
                     /db_xref="GeneID:71927873"
                     /locus_tag="MW046_RS07460"
                     /old_locus_tag="MW046_07460"
     CDS             complement(15285..15725)
                     /codon_start=1
                     /db_xref="GeneID:71927873"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004216253.1"
                     /locus_tag="MW046_RS07460"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MW046_07460"
                     /product="PIN domain-containing protein"
                     /protein_id="WP_247992505.1"
                     /transl_table=11
                     /translation="MSTSYVFDTEAIIAYLYKEPGHETISSLLDTVFTGNGEGVLSETN
                     ASEVFYLVARFEGTAEETPTTDSLRLADRDIRALNRRGLAIESADWRLTGEIKADGSLS
                     IADATAVALAHEQNATLVIGADDDFDALPVDVACKRFRTEGV"
     gene            complement(15722..16018)
                     /db_xref="GeneID:71927874"
                     /locus_tag="MW046_RS07465"
                     /old_locus_tag="MW046_07465"
     CDS             complement(15722..16018)
                     /codon_start=1
                     /db_xref="GeneID:71927874"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004216254.1"
                     /locus_tag="MW046_RS07465"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MW046_07465"
                     /product="AbrB/MazE/SpoVT family DNA-binding
                     domain-containing protein"
                     /protein_id="WP_247992506.1"
                     /transl_table=11
                     /translation="MACNTNDPTVVRVSQKGQATIPKPLREKFGIETPGEVFVYEEGNR
                     IILEPVPTPNDLHGIHASDHSSGDVLDRVREITDEEQRHEEERAERLHPSGDE"
     gene            complement(16135..17502)
                     /db_xref="GeneID:71927875"
                     /locus_tag="MW046_RS07470"
                     /old_locus_tag="MW046_07470"
     CDS             complement(16135..17502)
                     /EC_number="3.13.2.1"
                     /GO_function="GO:0004013 - adenosylhomocysteinase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /db_xref="GeneID:71927875"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) 2-Hacid_dh_C"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008013314.1"
                     /locus_tag="MW046_RS07470"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MW046_07470"
                     /product="adenosylhomocysteinase"
                     /protein_id="WP_247992507.1"
                     /sec_met_domain="2-Hacid_dh_C (E-value: 1.9e-10, bitscore:
                     37.6, seeds: 135, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSATYSRITEQLDDHEAAVESGRQKIDWASQHMPICSTLREEFEA
                     SQPFEDQRIGMAMHVEAKTAVLVETLAAGGAEIAITGCNPLSTHDDVSAALDAQQNITS
                     YAKRDLPEEDYYAAIEAVIDIEPTITVDDGGDLVFRIHEEHPELIDGIIGGCEETTTGV
                     NRLRAMDEDGALDYPVFAVNDTPMKRLFDNVHGTGESSLANIAMTTNLSFAGKTVVVAG
                     YGDCGRGVAKKASGQNAHVIVCEVDPRRALEAHMEGYDVMSMRDAAPKGDVFLTATGNT
                     DVITREHFERMSDGVVLANAGHFDVEVNLEDLSELSTSVTEVRDGVQEYELPDGRRLNV
                     LAEGRLVNLAGPRALGHPAEVMDQSFGVQAVCVRELVGAHETGLPDRLLTAIRDRFGRA
                     NGSRAVANHGYEDGVHEVPDVLDREVASIKLDAENITIDELTEEQQEYVSSWQHGT"
     CDS             17632..17760
                     /gene="allorf_1459608_1459736"
                     /locus_tag="allorf_1459608_1459736"
                     /protein_id="allorf_1459608_1459736"
                     /tool="antismash"
                     /transl_table=1
                     /translation="MNWNQTVLLAALCGLRLVGFKPSSDLSTPTHVRVQQNGDGGI"
     CDS_motif       17632..17664
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence: MNWNQTVLLAA"
                     /locus_tag="allorf_1459608_1459736_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       17665..17760
                     /prepeptide="core"
                     /locus_tag="allorf_1459608_1459736_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class II"
                     /score="-5.30"
                     /molecular_weight="3162.6"
                     /monoisotopic_mass="3160.7"
                     /core_sequence="LCGLRLVGFKPSSDLSTPTHVRVQQNGDGGI"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MNWNQTVLLAA"
                     /leader_location="[17631:17664](+)"
                     /alternative_weights="3180.6"
                     /alternative_weights="3198.6"
                     /alternative_weights="3216.6"
                     /alternative_weights="3234.6"
     tRNA            complement(join(17742..17777,17973..18010))
                     /anticodon=(pos:complement(1459950..1459952),aa:Trp,
                     seq:cca)
                     /db_xref="GeneID:71927876"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /locus_tag="MW046_RS07475"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /old_locus_tag="MW046_07475"
                     /product="tRNA-Trp"
     gene            complement(17742..18010)
                     /db_xref="GeneID:71927876"
                     /locus_tag="MW046_RS07475"
                     /old_locus_tag="MW046_07475"
     gene            complement(18088..18321)
                     /db_xref="GeneID:71927877"
                     /locus_tag="MW046_RS07480"
                     /old_locus_tag="MW046_07480"
     CDS             complement(18088..18321)
                     /codon_start=1
                     /db_xref="GeneID:71927877"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011323400.1"
                     /locus_tag="MW046_RS07480"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MW046_07480"
                     /product="DUF5795 family protein"
                     /protein_id="WP_247992508.1"
                     /transl_table=11
                     /translation="MTKKENRVVQGRMVTPESLAERIEDDSVMDAESISDTDRECPDCG
                     GPVVSVGYMPSVMEFVTGYKCQDCDWKATDRE"
     CDS_motif       complement(18229..18321)
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence: MTKKENRVVQGRMVTPESLAERIEDDSVMDA"
                     /locus_tag="MW046_RS07480_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       complement(18088..18228)
                     /prepeptide="core"
                     /locus_tag="MW046_RS07480_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class II"
                     /score="-4.80"
                     /molecular_weight="4981.5"
                     /monoisotopic_mass="4978.2"
                     /core_sequence="ESISDTDRECPDCGGPVVSVGYMPSVMEFVTGYKCQDCDWKAT
                     DRE"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MTKKENRVVQGRMVTPESLAERIEDDSVMDA"
                     /leader_location="[18228:18321](-)"
                     /alternative_weights="4999.5"
                     /alternative_weights="5017.5"
                     /alternative_weights="5035.5"
     gene            18458..19159
                     /db_xref="GeneID:71927878"
                     /locus_tag="MW046_RS07485"
                     /old_locus_tag="MW046_07485"
     CDS             18458..19159
                     /codon_start=1
                     /db_xref="GeneID:71927878"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="MW046_RS07485"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="MW046_07485"
                     /product="hypothetical protein"
                     /protein_id="WP_247992509.1"
                     /transl_table=11
                     /translation="MTNWFPSREWLAAYRDRLNENETYEEQSEGWGVDFDGGFVFEITE
                     LPVAETTIGELPPELSDAFRERLESVSESRIEELIEAAPHELTERMSDVTTDSQRERFV
                     TALFETEIENAPTVTWPDLNTEMPDDLENLLDQLERYVHEDTVYASLDLHDGECRTAEV
                     LETPPEGGTGFVLTAPYSKWTELIEGADVIEAVMSQDMNLDGDITSVIIYPEAAQEMGD
                     TAGRMETTFLF"
     gene            19320..20366
                     /db_xref="GeneID:71927879"
                     /locus_tag="MW046_RS07490"
                     /old_locus_tag="MW046_07490"
     CDS             19320..20366
                     /codon_start=1
                     /db_xref="GeneID:71927879"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006108331.1"
                     /locus_tag="MW046_RS07490"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MW046_07490"
                     /product="ribonucleotide-diphosphate reductase subunit
                     beta"
                     /protein_id="WP_247992510.1"
                     /transl_table=11
                     /translation="MSQVLQSQYSGQRVDTGSKWYTLFQKGVELGTWNVEKLFEEIGFE
                     QDRESWQRLSQNERDQIRYLISGFLDGEREVAGDAATNLQRIMGAPCLDGNTEKEMYMT
                     MLTLTEHKHTQFLDVYMQEVMDDRDNYNDLDPRRGARIPVVQATGLGEVFEHQGLLTAK
                     AANTLDPVDIAKAATNYHLNVEGILARVGASAISRFPERADFPLLNYAFKFVSTDEGRH
                     ITHGIELLKELIEKEEAGDPQFQGVKQGIIETLYQDVPYMADFGYMFTDALDDPLELDF
                     NEVLMRGGNLIDGMYNETLGLDVDYMEVLNVVRDRYLEINEWDIKQRVHEQEQHYQRKR
                     GVAADGGI"
     gene            20368..20655
                     /db_xref="GeneID:71927880"
                     /locus_tag="MW046_RS07495"
                     /old_locus_tag="MW046_07495"
     CDS             20368..20655
                     /codon_start=1
                     /db_xref="GeneID:71927880"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007737145.1"
                     /locus_tag="MW046_RS07495"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MW046_07495"
                     /product="hypothetical protein"
                     /protein_id="WP_247992511.1"
                     /transl_table=11
                     /translation="MALDRELRELARGAEFTATDEEVDQAIEDAAEELGEPPEQVRENV
                     AYIMDSTFEEEGVSTSFNEMVSGTSLEDDVSSTGDPRLEALEMYKLRQRI"
     gene            20662..20979
                     /db_xref="GeneID:71927881"
                     /locus_tag="MW046_RS07500"
                     /old_locus_tag="MW046_07500"
     CDS             20662..20979
                     /GO_function="GO:0051536 - iron-sulfur cluster binding
                     [Evidence IEA]"
                     /codon_start=1
                     /db_xref="GeneID:71927881"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006824767.1"
                     /locus_tag="MW046_RS07500"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MW046_07500"
                     /product="2Fe-2S iron-sulfur cluster-binding protein"
                     /protein_id="WP_247992512.1"
                     /transl_table=11
                     /translation="MSTDYEVTFEFEGDTTTVTVPDDEYILDAGHEAGLDLPFSCRNGN
                     CTSCVGKLLDGDVDQSDGLALEADQKEDGYALLCSSYPRSDCHIEAGDGVQQELLGLDM
                     L"
     gene            complement(21004..22278)
                     /db_xref="GeneID:71927882"
                     /locus_tag="MW046_RS07505"
                     /old_locus_tag="MW046_07505"
     CDS             complement(21004..22278)
                     /codon_start=1
                     /db_xref="GeneID:71927882"
                     /inference="COORDINATES: protein motif:HMM:NF024753.4"
                     /locus_tag="MW046_RS07505"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MW046_07505"
                     /product="PQQ-binding-like beta-propeller repeat protein"
                     /protein_id="WP_247992513.1"
                     /transl_table=11
                     /translation="MKERVPMSGRRSFLKSVVVGSVGFGVVGYGSDRVTAASSQHSEGV
                     WSQFKADAGQSARLPAGAGPTGDIQEAWTVSHDRIHDGVAVVDQTVYVGGKTLVALNTQ
                     DGTVQWSFEPDLPDIDDPGEPLIPDVGSPAVVDGTVYANVWFGPYDGGTYDTAFIAVDA
                     DTGERRWRIDTGGASSRAFASPTVTDDTVLTTMPQGEGYGSSRMVTALGLDGTLRWQTW
                     IEEMYSGSLPVSENRVYVPTASGVRTLDLETGSTVWTALPQVQFQPAAAPLVSDGTLFV
                     AETADPGVTFIALDAATGNEHWRTAYAPDARYSTGIGTVDDERVYLQLGAIDDDVIALD
                     RADGSERWRAAIDQPDTKRVPTDGVARVGDLLYVGGAAIDPTDGSTVWKHPLPVAGYGR
                     ELSAVAGGRVYVGGQGLTALTGTTE"
     CDS             22823..22909
                     /gene="allorf_1464799_1464885"
                     /locus_tag="allorf_1464799_1464885"
                     /protein_id="allorf_1464799_1464885"
                     /tool="antismash"
                     /transl_table=1
                     /translation="MWMSAVISIGTGRLEEKRRIEKACTWET"
     CDS_motif       22823..22891
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence: MWMSAVISIGTGRLEEKRRIEKA"
                     /locus_tag="allorf_1464799_1464885_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       22892..22909
                     /prepeptide="core"
                     /locus_tag="allorf_1464799_1464885_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class II"
                     /score="-7.20"
                     /molecular_weight="602.6"
                     /monoisotopic_mass="602.2"
                     /core_sequence="CTWET"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MWMSAVISIGTGRLEEKRRIEKA"
                     /leader_location="[22822:22891](+)"
                     /alternative_weights="620.7"
ORIGIN
        1 cgatcccctt ggtcccgaac ggctggcccg tctgcatggt caatgcacac cggatcagtc
       61 acaccgtggg cgcgcccgag ccgatctccg gacctgtgca gggtatttat ctctcgaaac
      121 accacgctcg tccgcagaca acgggggacg gatcgaaaac ggaacgatca gtgttgtacg
      181 ttcgtctcga actgtcgtct gactttctcc actttcggct gtgcgtgcgc ctgacagtag
      241 gcgtcggtgg gattcttctc gaaatagtcc tgatggtact cttcagccgg ccagaactgt
      301 tcgagtggtt ccagttcggt cactacgtcg tcgtcgtact cggcgtcgag cgcatcgatg
      361 tacgccgacg ccgtcgtccg ctgttgttcg tcgtgataca gtacgatcga tcgatactgg
      421 gtgccgacat ccggtccctg ccggttgcgc tgggtcggat cgtgcgtccg aaagaacgcc
      481 tcaagcagct cgtcatacga ccgtacgctc ggatcgtatt cgacctgtac gacctcggcg
      541 tggccagtct cgccggaaca gactgcctcg taggtgggat cgtccacgtg tccgccggcg
      601 taacccgacg tgaccgactc gacgccgtca aggactttca tcgcggcctc agtacaccaa
      661 aaacagccgc caccgaacgt tgcatcgtcg gtcatacttc acgtacggca ccgaacggta
      721 tgtatgtggc gcgcgggtgt cactcacgca actgtcgcag ttgtgcgtcc gtcagatcga
      781 tctccgcagc ggcaacgttc tcttcgagat gatcgacgct cgcagtgccg gggatcggaa
      841 ggatcaccgg cgaatgatgg agtaaccacg cgagcgcgat ctgttgtggt gtcgcgtcgt
      901 gttcatcggc caccgttcgg agcgcgtcgg cgttctcgcc gatcgatcca gcgtccatgg
      961 gtgcccacgg aatgaatccg atgtccgcct cctcacaggc ttcgagtacg tcttcgtcgt
     1021 cgcgcgtcgt aacgttgtac ttgttttgga cggttgcgat ctccgtgatg tctctcgctc
     1081 ggtcgatctg ttcgacagtg acgttgctca atccgagatg gtcgatcacg ccgtcatcgc
     1141 gtagttcagc gagtgccgtg atcgaatcct caaaaggtac ctccggatcc ggtcggtggt
     1201 actgatacag gtcgatcgtc tcgacgccga gacggtcacg gctacacaac accgcgtttc
     1261 ggaggtagtc cggatcacca cagggacgcc agtcgccgtc tcggttccgg aggagaccgc
     1321 ccttcgtggc gatcacaagc tcctcgggga agggatggag cgtctcgcgg atgagccgct
     1381 cactcacgcc cggcccatac gaatcagccg tatcgatgag gtcgatgccg agatcgatcg
     1441 cgcgccgaag caccgccttg gcggcgtttt cgtccgttgg cggcccgatg atcgcctccc
     1501 cggtgagtcg catcgcaccg aaaccgagcc ggttgacagt cagttcccca ccgatgtcga
     1561 acgtcgttgg agtggtatca gccataccct gaacaacgac ggactcgaag taagaggttg
     1621 tgacgtcgaa tcgaacgaca ggttcaccgc cactcgttga gtcgcgctcg gatttcgtat
     1681 cccgtgaccg atccgttggc cccggtcgtg atccgtcgca accgctctcg tcggctcccg
     1741 agttgggcga cgtcctcggc ggtgagacgc tcccctcggt agcggttgta gctgccgatc
     1801 cacgcgggct gatcgacgtc gctctcgtcg gtgacgtgtt cataatcgag tgctacgatg
     1861 gatcccgacc gcgaaacgcc gatctgtccc gctccatcga gtccgagtcc taatccagcg
     1921 tcgtcgagtc gtttctcgaa cgtcgaaacg cggcgttcgt actcctcctg ttggcgcgtc
     1981 tgggagtgat ccactgctct ctccgggtaa tcataaccga tcgtttcgac ctcctccatc
     2041 acgagccacc gatagtcttc ggcgtgatcg ataacgggcg cgaacagccc cgatacaccc
     2101 cgttcttcgg cctgttccca gatcatcgct tcgacccagt ttcccatctc cgtgcgagga
     2161 gtgtcggggt tcacgtcgaa ttcgatcttg aggacgtagt cgtgaggtcc acgaacgatc
     2221 ggctcaccgt ccaaccgagc cggcagccgc ccagcaaccc ggttgcccga gccgacgctc
     2281 catccgaacc cgtggagcgc cgtgagctgc ttccactccg cgtacggact gtcgtccgtg
     2341 gtgtacagct cctcggtgag gcgatcgcac agtgctcgtc cacgatccgt gagcagcgag
     2401 tccgattccg acgatggcac tgtcatcggt ctgagtcccg tacacgtcct gttgaccatt
     2461 catcgtatca atgaatcggt ttacgagcgg taacagctcc gggtccaaca gagccgtcgc
     2521 ggtcattgtc gttggattca acagtatccc gtcgatttcc cgatgcggct tggagagttc
     2581 atcgagggcc ttgaacgcat cacatggcgg gtgttgacaa cgaataccac cagattcctc
     2641 cggattggct gcgagtcgct cggcagaagg cttataccac caccattcct atcgttaggt
     2701 acggtcatcg ggatagtatt tacagtaaac gaactatcac gtgatcggat caaggggatc
     2761 cactatgagc gttatcaacc ggatcagtga tgcttttttt gacaaagagc acgatcaggg
     2821 tccctacgcc tgtcagagct gcgatcgtcg gttttcactt caataccagg tttgtcccga
     2881 gtgtgggggc tacgcgatcg aacgcgtcga ttggtcggag catattcaaa ataaatgatc
     2941 gcttcccgcc ggttcgatcc tatcgtccgg tcgggtatcg gattcggcca tgagcggtgg
     3001 aaacgattat gacgattgct gtggtatagg aaaacatggt ggaggaaccc atgctgaaag
     3061 ggatgccgcg atgtctcaac tgcggctttg aagccccaca cgatggtgga gaatggaact
     3121 ccgcccaggt acccccactc ggtgatctca tgcgctgccc cgaatgtggt agcaccaaca
     3181 ttctcgggcg ctggtgatcg ccggaagagc gttatcgatc cgtaggcaca gctgttatac
     3241 tcgttctcgc aggccccaaa caccgtgaga ccgtgagttc aatcgccgtt tgctgccgta
     3301 atcctacgac agcgtcttca attgccttgg atgcggggcg cgagcacgaa ggtgacagac
     3361 ccgtctccgg cagcgatatc gaaatggaga ttgacaggga actcctcgcc gagctcgacg
     3421 ctcacttcgg cgtcgttcgg gatcgccttg ttcatctctt tgaggtaatc gaggctgaac
     3481 aacgagtggg cgtccccggc agagagcatg atgagttcat cacggtcgag ttcgaaatgc
     3541 acgtcgtcag tgtcgccttc cgcatcgaca tagaagtact cctcatcggc gtcaacgccg
     3601 agcgcgatgt ggtcggacac catatcggcg gctgttaccg cccggtcgat gtcccgtcct
     3661 tcgatgccga tcgtagcaga cagatcgagg tctggaagat ctggctcctg tcggatggag
     3721 tcgggatcga tgagcgccag cgtgtactcc agtccatcga tctggatgtg aagctttcgc
     3781 gtcgtctcat cgagttccaa gtggatcaga tcatccgcgt tggccatgcc agcgatgtcc
     3841 tcgagtcggg tgaggttgac cccgatcgtc tctccatccg tctcgtagga ttcgaacgca
     3901 ctcgtatcga gccggaggtt taccatccca gcgttggcgg gatcgaccgc ccgaatggta
     3961 gcgccctcct cgtcgagtcg gatcttacac tcatcaacca acacgctcac cgagtcgagt
     4021 gctgccaaca gcgtccccga actcacgata gccgtgaaca tggatggcga ttctcctcga
     4081 cgggttaaaa aacgattcat tcatccaatt cagggtggct gaccgacgtc ccgacagtca
     4141 acgatccacc tcacccgggg gctacccaga ccagtccacg ttaggaagag atcgtttcga
     4201 gtacactgcg ctcctcggct cggtcgggac ctcgttcgac cgtctgtaca gtggagacaa
     4261 cgtgatcgac agtggttgtg accgtctctg gaatcggtgt cgcctcccag ccgatcgatt
     4321 cgagtttgtg agtgtcgaga acgtgagggt agtcgcgata cagcgggaaa tcagagggat
     4381 cgaggggggt agtggcgagt tcgcgctcgc tcatttcgat cggttctgcg ctcgtcccga
     4441 gcgcgtcagc gatcagttcg atccactccg tgagcacagg gagcgtgtgg gttccaacgt
     4501 tgtacgcggt accagcatcg ccgcgttcgg cgatcgttct gatggcgctg gccacatcgc
     4561 ctacgtacac gagatgacgc agtgcgctgt ggggaacgat gatgcggtcg tacgcatgga
     4621 cccgatcgat ccagtacgca aagcggtcgg tgtagtcgtg tggaccgtac acgatcggcg
     4681 gccggacgct catcgcacgg acgccccggt cgccagcggc aaagacggcc cgatccccgt
     4741 ctgccttccg cggaccgtac gtttcccagg agtcgtcagt cgcctgttcg gggctgcacg
     4801 cacacaaagg ggtttcttct tcccgttttg ggatcacttc cgttccgtag gccgcgccgc
     4861 tggaaacgta cacgtacgcg tcggtgtcgg cgaagatctc cgtcgcggac tgaacgtttg
     4921 cgggatgata ggccacacag tcggcaacga catcgggatc gatctgtctg cgtgcgcggt
     4981 cgagcgcgtc gtcgtccatc cgatcgccgg tgacgtgaac gacgtcatcc cgagcaaacg
     5041 aactgtcgtg gcgtccccgg ttgaagatcg caacatcgta tccgtggttc cgaaactcac
     5101 ggacagtgtg ccgaccgatg aatcgcgtcc caccgatgat gagggctgtg tccatgttct
     5161 ccgtattacc gcccatccaa tggatgtact ggtgtgcggt acacatttct ttgatcacta
     5221 ctgactacga ccatggccga cgatccagcg tcacacaccc ctgggaaagg aaaaacaccg
     5281 acggcacagc cgatcgaagc cgggagtccc gaggcgttcg ggttcgttca agcgtggtgg
     5341 ggagatggaa aaggcaaaac gactgccgcg ctcgggatgg gactgcgcgc cgtcggccac
     5401 ggctaccgag ttcaccttct ccagttcatg aaaggcggcg cgtccagcgt cgagtccgtt
     5461 cgtggcgagt acaacgctat cgcaacactg ccggggttta gctacgaaaa cctcggccat
     5521 tacggctggc acgcgctgaa cgacggtacc gatgaccacg atcacgagaa aaaggccatc
     5581 gctggctacg aacgcgcaac gcagctgatc gaggcgatcc acgaagccaa cctcaccgaa
     5641 ccgctcgaac tcgacgctcc accggaacag ggcgtccaca tgctcgtgct cgacgaactg
     5701 ctgtacgcca cagaacgagg gctcatcccg ccaacagacg tagtagatct catcgaaacc
     5761 aaacccgacg atctcgagct cgtgctcacc ggtggccacg agcgacccga gttcctcgaa
     5821 gcccacgcgg acctgatcac ccacgtcgat aaagacatcc acccatttga ttcaggacaa
     5881 agatccagac aaggaactga atactaataa ataaatttgt ataatacagt cccaaattta
     5941 tatactacac ataacgattg gatagaaaac gaaacattaa ttgtggcagc gttaacgaat
     6001 tgcggtggag gacaaggcgg cgcacgctcc ctttgttcct ctcgcgcccg gctagggtac
     6061 ggagcgacac acgctcaacc ccatgactca cacgctcctc gtcgcgggaa cagcgagcca
     6121 cgtcggaaaa acgactgtcg tggcagggct ttgtcgcctg ttcgcatccc tcgacacccc
     6181 tgtcgctccg tacaaagccc aaaacatgtc gaacaatgcc cgtgtagtcc cgacaccgtc
     6241 gggagagacg ggagagatcg gcgtttctca gtatattcaa gcgcgcgcag gcgacgtaca
     6301 cccgacgact gacgtgaatc ccgtgttgtt aaagccacgc ggagacggtg attcgcaggt
     6361 agtgatcaac ggacaggcag tcggtcatta tgaggcgcgc gagtattacg ccgagcactg
     6421 ggaccgtgct cgttcgatgg cacgagcgtc gtgggaacgg ttggctgaag agtacgagta
     6481 cgttatcgcg gaaggagcgg gatcgatcgc ggagatcaac ctccatcacc gtgatctcgc
     6541 gaacgtcgaa accgctcggt tcgcggacgc cgacatcctg ctcgtcgggg atatcgaacg
     6601 cggtggcgtc ttcggaagtc tcctcggaac gctgtcgctg ttgcccgacg atcttcgagc
     6661 acgtgtcgtt ggctgtctta tcacgaagtt ccgtggggat cgctcgctgc tcacccccgg
     6721 tatcgaagcg ttcgaacgac gaacgggagt tcccgttctc ggcgtgcttc cctacgacga
     6781 tccggggctt cccgaggagg acagcgtggc cttaccccca gaaaccgagc gcgctacgat
     6841 cgggggtgac gacggcgtcc cggagacgga atcggtcacg atcgccgttc cccgcctccc
     6901 acggatctcg aacttcaccg accttacacc gttagagcgc acaccgggcg ttcgggtgat
     6961 gtaccttccg ctctcggcgg gcaaacagct cacagatgcc gacgcggtcg tcgttccggg
     7021 gaccaaaaat acagtcgatg actgtctcgc gctccggtcg aacgggttcg acgcgtcgct
     7081 gcgcgcgttc gatgggccga tcgtcgggat ttgtggcgga tatcagctac tcggcgagcg
     7141 gctcacgaac gccgcggtcg aagcgaccgg ttccgtcgac gtggtcgaag gtgtcggggt
     7201 gcttcccacc gaaacacgct tttcgaccga gaaacacgtc gagccagtga gtcggacgat
     7261 ccacggctgt ggcccgctcg acggagccac cgggactgtc accgggtacg agatccacat
     7321 gggagagacg aagctgcttt cccccgtcga tcagccgttc gacggaacag gagcagcgac
     7381 cgatcgggtg cttggaacgt acgtgcacgg actgttcgag aaccggccgg tacgggaggc
     7441 gtttctcgac agcgtgttcg cccacgccgg actcgttcgg cccgaagccg atgaatcggc
     7501 gagaagagta gatctggagg cggcttacga ccgggcagca gatctcatcc gcgagcacgt
     7561 cgatctcgaa ccgctcggcc ttcctacctg agggtggaac ggcagtgtgt taacgactac
     7621 agatacgcac cgtcccagtc gtccggtcgg tggacgtttc cacattccgt acatttgatc
     7681 cgatccagct catcggccgc ttcgactgcc gaaccacagt tcgaacagta gaagccgtac
     7741 tgttcgtcgt aggtatcgtc gttgtacacc ggatggaagg gtgcagcatc gcccgggatc
     7801 gtgtcgtctg cgacgaatcg ttcgtcgccc tctgcgtcga tcgtcgaagg cacattctga
     7861 ggttcggctg gatccgtctc ctccgcctct ttggcggtcg gtgcgtagat gtgctctcgc
     7921 cagtcatcgc caccgaattc ggtgtcttgc tggtcgattc gttcgtagcc gaatcgttcg
     7981 gcaaagctgt cgccctcgga gttgctggcg agaattcgaa cgtgtacagc ggtcgctcct
     8041 cgatcgtgga gcgtttcgcg catccattcg aacagctccg tccccgcttt ctgcccgcgc
     8101 tcttcgggat gaacgtggag ccaccgcagt tcccccgtat cgtccgcgag ggtcccctcc
     8161 gcaaacccga cgacggagtc atcggtctcg gcaacgccga tcacgctctc atcgagtcga
     8221 tcctctatgg tttctacacc gaaccattcc tcaatgatga cgtcgattgc ggtgggactg
     8281 accgcgtacg acgcctgtat cgactggcgc gcgatatcgt aaatcctcgt ggcgtctgcc
     8341 tcggttgcgt tgcggacgtt catagtgaat gttgggtggt aacgggaata aaacgtgaac
     8401 tcggtctggc tctcgatggt tactcctctc tgtcgtagga cgtgacgcgt ccccacgtcg
     8461 attttttgcc ccacagtccg gatcgaagac actcacactc gacgatctgg gagttgtcga
     8521 tgaacatgtt cacgttcggg ccgaagtttt tgatgtacca ttcgaacatc tcgggaccgg
     8581 gcgcttcgaa cacgcagttt tcgagtccta gttcggtggc gatctgatag gcgacatcgg
     8641 tccgccaatc ggtcacgttc tcagtgatgc cttcggcttc gaccatcagc ttgtacgcgc
     8701 ctgcatcgag gtgacgacgc ccttcttcga tcgccagcgc gggatcctgc tgggtctctt
     8761 ctaacagctc ttcctcgcta gacgcaccgc cagcaccgaa ctgaacgttg atctcaggtt
     8821 tggccttcag tccgtgatcg acgaccagtt cggtgagtgc gaccacgtcg tcgacgtcga
     8881 tggcgaggaa acccgaggag atttccacga tgtcaaagcc tagctcccct gctttcgcaa
     8941 catagtcttc gacatgggcg ttgtccgcga cgagtacgtg ctcgataaac ccacctgtcg
     9001 agacttcgac gtcgaactcg tggcacgttt cgatcagctc gaccaccgcc tcttcgggca
     9061 tcaacgcgaa cgacccacca gagaacttgt agatgtccac gtagtgcccc atcgtttcga
     9121 gaatgtcgcg tagttcgcgc ggtcccatcg gatcgtagta gggaccacgg atctccgtga
     9181 tgcctttctc ccggggcttg tcaggacggt cgttcacccg gagaaattcg aacgctcggt
     9241 tgtctactgg catgccagca gtagacacag ttcccatcca cttatcggtt aaccgggagt
     9301 acgcaagcaa gaaacctcct ctgcataact cgaacgaaat cgtcttggca aacacaagcc
     9361 acaaacgatc cgaagccgct cgacgttgtt ggacgacgag aacggagacg tgttcgatgt
     9421 ggcactcagc gagaaccaca gtgatccccg gcgaacgtcc gacaacgtga tcctggatcc
     9481 catcgacgag aacccgatca ctctcataga atcactgaat tatccacatg tgtgacacat
     9541 accgaccccg ttagggaggt aggtacaggt actcactttc tgatcgtgaa cagtgtggtt
     9601 gtcatcgaac tgttcgtcgt acgcgtcctt gtcaacgtca acctcagtgt cgattgcgac
     9661 cgacatacat gatacattat gggataatgt attaaacctt ctgctatatt tgcatgatgc
     9721 aaaaataata aatatattga ttttcggcta tgatagggta aaatcagagg acgagaaata
     9781 gattggactc gaccactacg accaaatttt accccagtgg cagggcagct ttcctttttc
     9841 tctgtaaatt ttaccagaac atttaataat aagggatagg attggaggat atgttagtat
     9901 atattgacat agtaagagga catcgcacga gtcagcaaga gcacaggcag caagagcaca
     9961 ggcagcacgg taccgatttc gatggaagag accgataagc atggtggaac atctttcatc
    10021 cgaggaccgg cggacgatcg ctggacgggc ccgcacgata cacgaacgat tgaacggacc
    10081 ctcgaacgag ccgggaggag agccaccgat cgaccccgac gagatcgtgg cggagtggac
    10141 cgaactgttt ccagacgagg agtcgtttac cgagcgcctc gaacacgagg gactcaccga
    10201 agcggctgta tacgagcagc tgtcggcgac tcggtggcca gaagagacac cgactccgga
    10261 gtggatcgac gaactcgaat cgctcatcga tcacatcaaa cagttcgatc ccgacggtcg
    10321 acgcgctatt tccagtgaga tcccgttcgt ggatctgttg atcgcagttg ctgactacgg
    10381 ctgggcacaa ctcgccgatg agattcgacc accaaacggg gtaccgaagc tggaagaatg
    10441 gctgctcgcc cgtctcgggc ggctctgcgt tcgagccctg tacgtcgagt tcaaagcctt
    10501 catcgagtat cacgatccgg aactcgcggc aaccgatccc gaggacgttg ccgagccggg
    10561 gacagcgtac tacgatcggt tcatcgaggc gatgtttgac gacgggtttc ggaaactctg
    10621 tctcgaatat ccggttcttg cccggtttat cgttcggcag atcgagcagt gggtgacgac
    10681 cgttacggcg atctgtcgac ggcttcgagc cgatcgtggg atgctcgacg accgctttgc
    10741 gatcgatggt gagataacgg ccatcgatcc gttggccgat gatgcacacg cagggggtca
    10801 agtccccgtt cgcgtctcgt tcgaatccgg gtcggtcatt tacaagccac gatcggtcga
    10861 cgctggacgt ctcctgtaca ctgttctcga ccgactcggt tcacacctct caaccctcga
    10921 aatgaccgca cccacatatc tatcacgcga tggatatggg tggatggaaa cgatcgacta
    10981 ccgtgaaccg tcggacacag ccgctgttga cagctattac aaacgtgtcg ggatgttact
    11041 ctgtgtggca tacgttctcg atctcccaga ttgtcagttc gaaaatctga tggtgagtgg
    11101 cgatcagccg acgatcgtcg acgcggagac gattttccac ccctacatcg atcccgttgc
    11161 ggccgcttac acgacagagg ttgacgcagc catctcggac tcgatcctcc gtacagggct
    11221 actaccgtgg gcaatcggtg atatcggcga tgaggacaac gatctcaaaa aaccactttt
    11281 ggccgcaggc gttgggagta gcagcgagac gatagaagta tcggagatat cgaaaccgac
    11341 cgttacggca gtcaatacgg acgtaatgac gataacgggc gaagcgccaa ccgtcgatcg
    11401 gaccacgaac acgctgagca aagacggcac ggaccaccct ccagaagagc acatcgacac
    11461 gatcgtcgat ggatttcagc ggacgtacga cgtgatccgg gaactccacg agaacggacg
    11521 attccgttcg gagatcgtcg atccggagct gatcgctggg gtcgaaaacc gacttgtctt
    11581 tcgatcgaca gacatctact attcgatcct ccgcttgagc gttgcacgag atccgctccg
    11641 ggatggagga cgtctctcag tcgagttcga gcgacttgcg gcatggtttt tcaacgaccg
    11701 gatcgaatcc gatcggtatt gggggctgta cgacgccgaa cgtcggtcgc ttcgccagcg
    11761 ggatgtgccc cggttcaccg gccggcccgg tgggacggcg ttgtatcacg acggaacacc
    11821 cacgggtctc gatgccgatc tgtcggggta tgagcggtgt caacagcggc tcgatgccat
    11881 gggtagcgcc gacctacaaa cacaaacgtg gctcatccga cggtgtatcg acgattcgtt
    11941 cccggcacga gagaccccgt catctcccct cgagttgacc gacgaacggc ttcaagaaga
    12001 agcgatcaga tacggcgatc aggtgatcga tgcggcgatg gaaacgacgg tcggtcacag
    12061 atgggtatca tttatcggcg gggaactgcc acagctctgt gtctcaccag cagacaacac
    12121 gctgtacgat ggacggggcg gaattggact cgctgcagcg gcgatatacg atcgcaccgg
    12181 tcacgatcga ttccgcgatg tggcgatcga ggcgttggat ttagttgccg cagatcacgg
    12241 tgaatcgccg acggagttcg gcgggatcaa gggaaccggc tcaatcgtgt acacgctttc
    12301 ggtcgctgcc agtctcctcg atcggccgga ataccgggat cgtgctgcgg agtacgctcg
    12361 tgccatgacg agcacacaac tggaaggtcg accgttcgat ctggtcgatg gaactgcggg
    12421 aatgttactc gcgctgcttg cccactacga acggtacggg gggactgcga tccgtgatcg
    12481 agcgatcgac tgtggacaac gactcctcga tgggcgcgtt tcggtcgacg gccatcgcgt
    12541 gtggacgaca aacgacggtg atgcgatggc cgggtttgcc catggcgtca gcgggatcgc
    12601 atacgccctt gcacggctgg ctgcagtggt cggcgacgac cgctatggga gtgcagcacg
    12661 cgaggcactc gcgtacgaat caacgctgta tgttcccaag cgatcgaact acgcgatctc
    12721 ctccgaaccg gaccgatttc aagaccagtg gtgtcacggg cggactggct gtgcgcttgc
    12781 tcgactcggt atcggcgtgc aactcggaga cgacgagctg gttacagagg caaacgaact
    12841 gttatcggcg accgtcgagg ccgagttcag ccagtacgat cagctctgct gtggcaatct
    12901 cggacggacg gtaacactac tggaggcggc acgtcacacc gaccgagccg agaccgatgc
    12961 acgcgtcatc gctggtcagt gtcttgcacg cgaacaacag acaggagcat tgtcgatgtt
    13021 aggaaacggc gaaccagttc acaatccgac ctttttccac gggagtagcg gggctgccta
    13081 caccatactt cggctccgtg atcccgaggc gctcccgtgt gtgctactac tcgaatagaa
    13141 acatgactga acaactaaaa atcatcttcg aagtcgcttc cgccgctggt gaagaacggc
    13201 tgatacggga gtacatctct cccgcgttct cccggctgga acagcgcgat gatgcccact
    13261 ggccgatgtt taatcggtac gcccaagatc cctccgtcga gacgggcgaa gtagtactga
    13321 tcgttttcgg agctgtcgaa tcgatcgtcg gtgacgaacg cccccgatgg atcgatctcg
    13381 tcgacgatgg tgtactactc gactggcaat tagaaacgac aggtgtcgag accgatacgc
    13441 tcgacgaaca ggaacggttc cggtaccgtc tacgaaccgc agcaagccga atgagtctcg
    13501 aatttttcgg gacgttcgat ccgctccctg aatccgttca tgaactcgac accgagggac
    13561 gatcgatcgg ctgggagctg tgtcttcatc atatcatcaa tcaactcgga taccaagcaa
    13621 actgcggtga agaggagatc gatctcctct tccgagggct ggtcagccgg ttgtacgcga
    13681 tggcgatcgc gccggaatat ggccccgagt tcgcagagaa taaaatcgaa gagctgacaa
    13741 cagaactcga atcactgccg ccggagctac agcggtttca ggacgcccac cagccgtgag
    13801 tcagtatgtg gatggtcgat acgtcgccca caagggccat cacgatacgt ccaacaaccg
    13861 ggtgagatcg tccacgtcgt gttcgtcgag cgtacgcacg gtgtcgatga tctcctgctg
    13921 gcgagatcgg tcgtaccgat cgtcggtcat ggtggtgaat ttgtcttcga tctggttcca
    13981 cgacatgggg ttgttcggat ggccgctgaa atcatccgtt tcggcccggt gcgtggtgcc
    14041 atcatcgaat tctacggtga ctcgggcagg catctccccg cgctcgaagc gctctgtgaa
    14101 ctcctcgtct tcctcgaccg tcacggttcg caacagcgtt tggacgtcgt cacggttgat
    14161 tcgctcggga tcgtaggcgt cgttggtcag ctgccgatcg atgagcgctg cggcgagcat
    14221 gtacggcagc gagtggtcgg cttgggcttt cgattcgacc tcatagcgcg aaccttcacc
    14281 gccgccaatg atgagcttcg cgccagcgaa cgtgtcgagg tggattgact cgaccgtttc
    14341 cgggtcgatg tcgtggatct cagcgagttc gatgatcgct tcgacggcgg attgagcgta
    14401 cgtttccgcc acgtagcgtt tggtcatggt gtcgaagacg cgttcgcagt tcgagtcgag
    14461 agatacgtcg aattcgccgc taatgatctg cttccacccc ttttggccct cgaacaggtt
    14521 cgtcggaccc tccatcccgt gatccgcgag catcaccgaa tacaccgcgt tccgagcggc
    14581 gttcgcgctg gcgatccctt tccattcgtt gatgccgccg gttctggtga cccgaagcgc
    14641 gttgtgtgca gtaccagcga ttccgatggc gttgcgcagc tgttcccggt cgagaccgcg
    14701 aaccacgccc gcacccgtgg ccgccgacac caccgtgtgg gtcacatggt cgtagccacg
    14761 gtcccggaca ggggcgttcc acgccagttc gccctgcacc tcgtaggcaa caccgatgcc
    14821 cgcgagcagt tcacggccgg ttcgatcgcc agcttcggcg cacgcgatca cgctcccgat
    14881 gttgtcgctg ggatggggtg tttctcccgg cgcgagaaac gaatccatgt aatcgagata
    14941 ccgagtgagc gcggtgttgt acatcgcggc cccgaccggg gaggcagtac ggtcacttcc
    15001 ccacagccgg cacggcccat ccgattccag ttcggtgcag gtcgcccgca cgctgtcggt
    15061 tgcgtcggcc cccaacgcac caaccgcgat cccgatcgaa tcgagcacgc gctttttcag
    15121 ctcctcgcac acgtcttcag acagctcctc gtagctgact gacaacgcaa aatcagcgag
    15181 ttccgcggtt gtcgtcatac acgatacgtc tcttgggtgt cggataagcc cgtggccggc
    15241 atactcacag gtggctctga gccggggccg acaaccgaac agtatcaaac accctcagtc
    15301 cgaaatcgct tgcacgccac atcaaccggg agtgcatcga aatcgtcgtc cgcgccgatg
    15361 acgagcgtcg cgttctgttc atgagcaagc gcgacagcgg tggcatcagc gatcgaaagg
    15421 cttccatcgg ctttgatttc acctgtgagc cgccaatcag ccgactcgat agcgagtcca
    15481 cgccggttga gagcacgaat atcccggtcg gccagccgga gcgagtccgt tgtcggtgtc
    15541 tcctcggccg tgccctcaaa gcgagcaacg agataaaaga cctcgctcgc attcgtctca
    15601 ctaagtacac cctccccgtt cccagtaaag acggtatcga gaagggagga gatcgtttcg
    15661 tgaccaggtt ccttgtacaa gtatgcgatg atcgcttcgg tgtcgaagac gtagctcgta
    15721 ctcattcgtc cccagaagga tgcaatcgct cggcccgctc ctcttcgtgg cgttgttctt
    15781 cgtcggttat ctcacgcacc cgatcgagga catcaccgga ggaatgatca ctggcgtgaa
    15841 taccgtgaag atcgttgggc gttggaactg gctcaaggat gatgcgattg ccctcctcgt
    15901 agacgaacac ctcgcccggc gtctcgattc cgaacttttc ccgcaatggc tttggaatcg
    15961 tcgcctgccc tttttgggat actcgtacaa cagttggatc gtttgtatta caggccatcc
    16021 atagttgtat ctaaagacgc tatcattact aaacgttccg ccacccacca cgcttcaacg
    16081 gctcttgcgg ataccaatag taacgacagc gaatatttga caagcgatcc gaagtcacgt
    16141 cccgtgttgc cagctactca cgtactcctg ttgctcctcg gtgagctcgt cgatggtgat
    16201 gttttcggcg tcgagtttga tgctggcgac ctctcggtcg agcacgtcgg gcacctcgtg
    16261 aacgccgtct tcgtagccgt ggttggcgac ggcccgcgag ccgttagcgc gtccgaaccg
    16321 atcccggatc gccgtcaaca gccggtctgg aagcccggtt tcgtgtgcac cgacgagttc
    16381 tcggacacaa accgcttgca caccgaaact ctgatccatc acctcggccg gatgaccgag
    16441 cgcgcgggga ccagcgagat tgacgagccg accctccgcg agcacgttca accggcggcc
    16501 gtccggtagc tcgtactcct gaaccccatc tcggacttcg gttaccgagg tggacagctc
    16561 ggaaagatcc tcgaggttca cttccacgtc gaaatggccc gcattggcga gcacgacgcc
    16621 gtcactcatc cgttcgaagt gctcgcgcgt gatgacgtcc gtgttgcctg ttgcagtgag
    16681 gaacacgtcg cctttgggtg cagcgtcacg catcgacatg acgtcgtatc cttccatgtg
    16741 cgcttcgagt gcgcggcgag gatcgacctc acagacgatg acgtgtgcgt tctgtcccga
    16801 agcttttttg gcaactcctc ggccacagtc gccgtatccc gcgacgacga cggttttccc
    16861 ggcaaacgag aggttagtag tcatggcgat gttcgccagc gaggactctc ctgtgccgtg
    16921 aacgttgtcg aacagccgtt tcatcggcgt gtcgttcacc gcgaacactg gatagtcgag
    16981 cgcgccatcc tcatccatcg cgcgcagccg attgacaccc gtcgtcgtct cctcacaacc
    17041 accgatgatt ccatcgatca gttccggatg ctcctcatgg atgcggaaca ccagatcgcc
    17101 gccgtcgtcg acggtgatcg ttggttcgat gtcgatgacg gcctcgatgg ctgcataata
    17161 gtcctcctcg gggagatcgc gtttcgcgta ggaagtaatg ttttgttggg catcaagcgc
    17221 ggcactcacg tcgtcgtggg tcgacagcgg gttacacccc gtgatggcga tctccgcacc
    17281 gcccgcagcg agcgtttcga cgagtacggc cgtttttgcc tcgacgtgca tcgccatccc
    17341 gatgcgctgg tcctcgaagg gctgggaggc ttcgaactcc tctcgaagcg tcgaacagat
    17401 gggcatgtgc tgactcgccc agtcgatctt ctggcgtccg gactcgacgg ccgcttcgtg
    17461 atcgtcgagc tgctcggtga ttcgggaata cgtcgcgctc attggtgggc gttgactgag
    17521 cggtgggaaa acggtatcga agcgtggata agcacagctc ggtttatggg atagtcgaga
    17581 tctcagtaca cccactcacg ttcgagtaca acaaaatggg gacggaggga tttgaactgg
    17641 aaccagacgg tcctgctcgc tgcgctgtgc gggctgcgac tggtagggtt caaaccctcc
    17701 tcagatctca gtacacccac tcacgttcga gtacaacaaa atggggacgg agggatttga
    17761 acccccgatc gactgatatc tccggtttcg cctcggtact ccagagggtc gtcatcgcgg
    17821 gcggtgatca gccccccgct cggtatatca gttctggagt gtcgtcaccg gccttcggcc
    17881 ggttgcttgc ggaacgttgt tccgctctat caccggacta cgtccgattg cttgaggcac
    17941 ggagtgcctc tctgtcaccg ggcgtgtgac ctctggagtc agtcgccatg cctggcttgg
    18001 ccacgtcccc gtacccccaa gaaaggccat cttccctaaa gcggtttcgg ttcagtaggt
    18061 gagcgttcga tctcggctcg aacgtcgtca ctcccggtcg gtcgctttcc aatcgcagtc
    18121 ctggcatttg tagccagtca cgaactccat cacagacggc atgtatccaa ccgaaacgac
    18181 gggaccgcca cagtccgggc actcccggtc agtatccgaa atggattcgg catccatcac
    18241 tgagtcgtcc tcgatgcgtt cggcgagcga ttccggtgtc accatccgtc cttgcacgac
    18301 gcggttttct ttcttggtca taccaacagt gttcgaacca ctgaaactaa accgtgttcg
    18361 tctcaccgcc gatcgcatgc accgaagaac ggaacccaaa taaatcacca gccatccaag
    18421 cccgtatcct catgcgagtc gctcacagag cacgcccatg acgaactggt ttccatcgcg
    18481 cgaatggcta gcagcctacc gggatcgact gaacgaaaac gaaacgtacg aggaacaaag
    18541 cgaaggatgg ggtgtcgatt tcgacggcgg cttcgtcttc gagatcactg aactcccggt
    18601 cgcggagacc accatcggtg agttgccacc ggagctgtcg gatgcgttcc gtgagcggct
    18661 cgaatccgtc tccgaatccc ggatcgagga actcatcgag gcggcacctc acgaactcac
    18721 cgaacggatg agcgacgtga cgaccgatag ccaacgagag cgattcgtga ccgcgttgtt
    18781 cgagaccgaa atcgagaatg caccgaccgt aacgtggccc gacctcaata cggagatgcc
    18841 cgacgatctc gaaaatctcc tcgatcagct ggaacggtac gtccatgagg atactgtgta
    18901 tgcctcgctc gacctccacg atggcgagtg ccgcacagca gaagtgctcg aaacgcctcc
    18961 cgaggggggt accgggttcg tcctcaccgc tccatacagc aagtggaccg aactcatcga
    19021 aggagcagat gtgatcgagg cggtcatgtc acaggatatg aatctcgacg gggatatcac
    19081 cagcgtcatt atttatcccg aagccgcaca ggagatgggc gacaccgccg gcagaatgga
    19141 aacgacgttc ctgttttgaa aatatttgga aaatgaattg ttatttgaga aaccgattcc
    19201 ctcgatatgg tatctaatgt ttttctaaat taataataga agtgcatcca taacagttta
    19261 aattaccccg tatgcgcggc cgaaccctga tacggatttg acgacgaata gtggagtgta
    19321 tgtcacaggt gctccaatca caatactcgg gccaacgggt ggacaccggg agcaagtggt
    19381 acacactgtt tcagaagggg gtcgaacttg ggacgtggaa cgtcgaaaag ctgttcgagg
    19441 agatcgggtt cgaacaagat cgagaatcct ggcaacggtt gtctcaaaac gagcgagatc
    19501 agattcggta tttgatttcg ggatttttag acggtgagcg cgaggtcgcg ggcgacgcag
    19561 cgacgaacct ccagcgcatc atgggcgcgc cgtgtttgga tggaaacacg gaaaaggaga
    19621 tgtacatgac gatgctcacg ctgaccgagc acaaacacac ccagtttctc gacgtgtaca
    19681 tgcaggaggt gatggacgac cgagacaatt acaacgatct cgatccccgt cgtggcgcgc
    19741 ggattccggt cgtgcaggcg acgggactcg gagaggtgtt cgaacatcaa ggtctgttga
    19801 cggcaaaagc cgcgaacact ctagatcccg tggacatcgc caaggccgcg acgaactacc
    19861 acctgaacgt agaggggatc ctcgcccgtg tgggggcaag cgcgatcagt cggttccccg
    19921 aacgggccga tttcccgctg ttgaactacg cgttcaagtt tgtcagcacg gatgagggac
    19981 gccacatcac ccacgggatc gaactgctaa aagaactcat cgagaaagag gaggctggcg
    20041 acccacagtt ccaaggggta aaacaaggta tcatcgaaac gctgtaccaa gacgtgccgt
    20101 acatggccga tttcggctac atgttcaccg acgcactaga cgatccgctc gaactcgatt
    20161 tcaacgaggt gttgatgcgc ggaggaaacc tcatcgacgg catgtacaac gagacgctcg
    20221 gactcgacgt cgactacatg gaggttctca acgtggtccg cgaccgatat ctggagatca
    20281 acgagtggga tatcaaacag cgggtccacg aacaggaaca gcattaccaa cgaaagcgcg
    20341 gcgtcgccgc cgacgggggg atctgagatg gcactcgaca gggagctcag ggagctcgct
    20401 cgcggcgcgg agttcactgc gaccgacgag gaggtcgatc aggcgatcga ggacgctgcc
    20461 gaggagttgg gcgaacctcc cgagcaagtc cgtgagaacg tcgcatacat catggattcg
    20521 acgttcgaag aggaaggcgt gagcacctcg ttcaacgaga tggtgagcgg tacgagcctc
    20581 gaggatgatg tttcgagcac cggcgacccg cgcctcgaag cgctcgaaat gtacaagctc
    20641 cgacagcgga tctaacgaaa cgtgagcacc gactacgagg tcaccttcga gttcgagggg
    20701 gacacgacca cagtgacggt tccagacgac gagtacatcc tcgacgcggg tcacgaggcg
    20761 ggtctcgatc ttcccttttc ctgtcgtaac gggaactgta cgagctgtgt cggaaagctg
    20821 ctcgatggcg atgtcgacca gagtgacgga ctggcgctcg aagccgacca gaaagaagac
    20881 gggtatgccc tactgtgtag ttcataccct cgttcagact gtcacatcga agccggtgac
    20941 ggtgtccaac aggaactgct cggtctcgat atgttatgag tcagggccgt tagatccgga
    21001 tgattactcg gtggttcccg taagcgcggt gagtccctgt ccgccgacgt acacacgtcc
    21061 gccagcgacg gcactcagtt cccgaccgta gccagcgacc gggagggggt gtttccacac
    21121 ggtggatccg tcggtcggat cgatcgctgc tccgccgacg tacaggagat caccaacccg
    21181 tgccacgcca tcggttggga cgcgctttgt gtcgggctgg tcgatcgctg cccgccagcg
    21241 ctcgctgccg tccgctcgat caagcgcgat gacgtcgtcg tcgatcgccc ccagctggag
    21301 atacacccgt tcgtcgtcga ccgtcccgat tcccgtcgag tagcgagcat ccggtgcgta
    21361 tgcggtacgc cagtgttcgt taccggtcgc tgcgtcgagt gcgatgaacg tcacccccgg
    21421 atcggccgtc tcggcaacga acaacgttcc gtccgaaacg agtggcgcgg cagcaggctg
    21481 gaactgtacc tgtgggagtg ccgtccagac ggtactcccg gtctctagat cgagcgttcg
    21541 gacaccgctc gctgtcggca cgtacacacg gttctcagag accgggagcg atcccgagta
    21601 catctcctcg atccacgtct gccagcgcag ggtgccatcg agaccgagag cggtgaccat
    21661 ccgactactg ccgtacccct caccttgggg catcgtcgtc agaacggtgt cgtcagtgac
    21721 cgtcggcgaa gcaaacgctc gagaggaagc cccgccggta tcaattcgcc aacggcgctc
    21781 acccgtgtcc gcatcgaccg cgatgaacgc cgtgtcgtac gttccgccat cgtagggacc
    21841 gaaccaaacg tttgcgtaga cggtgccgtc gaccacggcc ggggaaccga catcgggtat
    21901 cagcggctcg ccgggatcgt cgatatccgg aaggtccggc tcgaacgacc actgaacagt
    21961 accgtcctgt gtgttcagtg caacgagagt ctttccaccg acgtacaccg tttggtcgac
    22021 gaccgccaca ccgtcgtgaa tgcgatcgtg agacaccgtc cacgcctctt ggatatcacc
    22081 ggtaggaccc gcgccagccg ggagacgagc cgattggccc gcatcggcct tgaactgcga
    22141 ccacacgccc tccgaatgct gactcgaagc cgctgtcacc cgatccgatc cgtacccgac
    22201 gacaccgaac ccaaccgagc cgacgacaac actcttgaga aacgaacgac gaccggacat
    22261 cggtactcgc tctttcattt caaatacaaa aaagatagta cattacaaat gttttctggc
    22321 catttcaggc acggaaagac agatcgaaga tgaaagggtt cgtgccgaac cacgaacggc
    22381 tctgtgctgt gtccgttaga cggttaagaa aaaacgagcc aaccagccag accaatcggt
    22441 gacccagagg gacaaatgag acgacactgg tgtacggtct gacgataacg gctgggacgc
    22501 cgctggtctg tacgaaaccc gtggttgaat cggtgaccac gggtatgtga caacgctggt
    22561 cggactatgc cagatgggac gccgggggat tgcttcgatt ggatgaaacc ttcacgtcac
    22621 gttgtggtat atccgacgtc cacatgatat tcagtgccac acaggtatga gtcttgtgcc
    22681 ccataagttc atatgcagaa ttagacatat tttatatcca ccacaattgt attcacgtgt
    22741 taggagatag aattcaatgt aaggttgctc gaaataactg agatcgcgat tataggatca
    22801 ctaccatcac agctacggtc tgttgtggat gtcggcagtc atctccatcg gaactggacg
    22861 gttagaagag aaaagaagga ttgaaaaggc gtgtacatgg gaaacgtgag gcgttacgtt
    22921 gctgtgttgc caactctact ggatcgggga gcagtacacg gtatcgtgat cccgaggttc
    22981 cagttgaaat gcagggaaag aaatgaacta actctgatac gtcgacacca gtctatcatc
    23041 acgccatgtg tatgtcgtgt gaataggtaa cactgattta tcgcgccaga ccatagtcgt
    23101 cgtatgatag ttgttgaatt ccgaatgaat tcaccgat
//
