LOCUS       NZ_JALDUX010000010     14765 bp    DNA     linear   CON 12-MAY-2024
DEFINITION  Streptococcus mitis strain S25 NODE_10_length_14765_cov_135.556577,
            whole genome shotgun sequence.
ACCESSION   NZ_JALDUX010000010
VERSION     NZ_JALDUX010000010.1
KEYWORDS    WGS; RefSeq.
SOURCE      Streptococcus mitis
  ORGANISM  Streptococcus mitis
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 14765)
  AUTHORS   Palmer,K., Luke,J. and Madison,Y.
  TITLE     Whole genome sequencing of viridans group streptococci associated
            with infective endocarditis and the human mouth
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 14765)
  AUTHORS   Palmer,K., Luke,J. and Madison,Y.
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAR-2022) Biological Sciences, The University of Texas
            at Dallas, 800 W Campbell Rd, BSB 12, Richardson, TX 75080, USA
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: SPAdes v. 3.13
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 209x
            Sequencing Technology             :: Illumina NextSeq 500
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_023109755.1-RS_2024_05_12
            Annotation Date                   :: 05/12/2024 04:19:48
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 1,953
            CDSs (total)                      :: 1,906
            Genes (coding)                    :: 1,839
            CDSs (with protein)               :: 1,839
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 23 of 67
            Pseudo Genes (incomplete)         :: 45 of 67
            Pseudo Genes (internal stop)      :: 16 of 67
            Pseudo Genes (multiple problems)  :: 16 of 67
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 14:27:13
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 0
            Orig. end                         :: 14765
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            JALDUX010000010.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     gene            <1..725
                     /locus_tag="M1F92_RS09515"
     source          1..14765
                     /country="USA: Texas"
                     /db_xref="taxon:28037"
                     /host="Homo sapiens"
                     /isolation_source="Endocarditis"
                     /mol_type="genomic DNA"
                     /organism="Streptococcus mitis"
                     /strain="S25"
                     /submitter_seqid="NODE_10_length_14765_cov_135.556577"
     region          1..14765
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="lanthipeptide-class-ii"
                     /region_number="1"
                     /rules="cds(LANC_like and DUF4135)"
                     /tool="antismash"
     cand_cluster    1..14765
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="cds(LANC_like and DUF4135)"
                     /kind="single"
                     /product="lanthipeptide-class-ii"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..14765
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="True"
                     /core_location="[3527:6518](+)"
                     /cutoff="20000"
                     /detection_rule="cds(LANC_like and DUF4135)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-ii"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      3528..6518
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="cds(LANC_like and DUF4135)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-ii"
                     /protocluster_number="1"
     CDS             <5..725
                     /codon_start=3
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260374.1"
                     /locus_tag="M1F92_RS09515"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="helical hairpin domain-containing protein"
                     /protein_id="WP_247933247.1"
                     /transl_table=11
                     /translation="TVREFEVELAENQIEKLVDEGIYIKMSFGINQSGLIFIPNYQLDI
                     LEEENQTKYKIFIRETTSYFVYNKEHSDKNQYVKGRTLIRQLTNDSRVIPYRRPTVKSL
                     QEKITEINLFIELTEVDKKYQDIKDELVKEIAEIDIKLNQINEKIANLNKMAEVLINLK
                     SEDVSSRKLARYDFSKLNLTESTSLEQVTEEIRALQEELGHHIGEYERLIKRLETFVKM
                     LNTGKGVNQKFDMEISLQ"
     CDS             complement(832..984)
                     /gene="allorf_00832_00984"
                     /locus_tag="allorf_00832_00984"
                     /protein_id="allorf_00832_00984"
                     /tool="antismash"
                     /transl_table=1
                     /translation="MIIDKNNNAAMRFCIFLPFLTSLNNRLLANSKIMTSWAPHSLSFL
                     SGSLN"
     CDS_motif       complement(955..984)
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence: MIIDKNNNAA"
                     /locus_tag="allorf_00832_00984_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       complement(832..954)
                     /prepeptide="core"
                     /locus_tag="allorf_00832_00984_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class II"
                     /score="-5.60"
                     /molecular_weight="4367.1"
                     /monoisotopic_mass="4364.3"
                     /core_sequence="MRFCIFLPFLTSLNNRLLANSKIMTSWAPHSLSFLSGSLN"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MIIDKNNNAA"
                     /leader_location="[954:984](-)"
                     /alternative_weights="4385.2"
                     /alternative_weights="4403.2"
                     /alternative_weights="4421.2"
                     /alternative_weights="4439.2"
                     /alternative_weights="4457.2"
                     /alternative_weights="4475.3"
                     /alternative_weights="4493.3"
                     /alternative_weights="4511.3"
     gene            <1014..1547
                     /locus_tag="M1F92_RS09520"
                     /pseudo=""
     CDS             <1014..1547
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017768984.1"
                     /locus_tag="M1F92_RS09520"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /product="helical hairpin domain-containing protein"
                     /pseudo=""
                     /transl_table=11
                     /translation="VWIKESSDLNRYMRGRELIRQLTHDSTHIPRRRRPTIANLKEKIA
                     EVNLLIELDFNNQSYQ"
     gene            complement(1652..2515)
                     /locus_tag="M1F92_RS09525"
     CDS             complement(1652..2515)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001093609.1"
                     /locus_tag="M1F92_RS09525"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="WP_247933248.1"
                     /transl_table=11
                     /translation="MNILSEKFRTKRKELGLSQQTLAEGICEQSQISKIERGRFIPSAD
                     LLFKLSQRLEVPLDYFFNEQIEVKSNLSNFKNLSSRLLEDRNYKDLEYLYKIELERNNF
                     LTLEDKMYLEWIKAIIDFYQYDHKYEAISYLENILSKVSSNTLIYLKVMNTLSNFYSLV
                     DREQEYEANYFHLMELYQTKNLDYQEFLFGYIRVRYNYAHYLVSKAKHNEAIQEALETI
                     ELCKKRQTSYQLAPLLILVGNAGEQFLDKEQVKNYYIEARELCKIYNNPLMLMKIENYL
                     KELDTF"
     gene            2708..2887
                     /locus_tag="M1F92_RS09750"
     CDS             2708..2887
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF040904.1"
                     /locus_tag="M1F92_RS09750"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="PhrA family quorum-sensing system peptide"
                     /protein_id="WP_033607253.1"
                     /transl_table=11
                     /translation="MRKKRGINQLMAFLLLGSIAFSNVFFYRQPNPKDTSAFSYEVRIG
                     VQNKSSGLDVGKAD"
     misc_feature    complement(2710..2725)
                     /note="TFBS match to ColR, Phenol-responsive regulator,
                     confidence: medium, score: 24.81"
                     /tool="antismash"
     gene            2990..3214
                     /gene="pneA1"
                     /locus_tag="M1F92_RS09530"
     CDS             2990..3214
                     /codon_start=1
                     /gene="pneA1"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000181087.1"
                     /locus_tag="M1F92_RS09530"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="mersacidin family lantibiotic"
                     /protein_id="WP_247933249.1"
                     /transl_table=11
                     /translation="MTNFNSNEKFCGKSLKSLSADEMSLIYGASDGAEPRWTPTPLILK
                     SAAASSKVCISALVSGIGGLVSYNNDCLG"
     CDS_motif       2990..3076
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence: MTNFNSNEKFCGKSLKSLSADEMSLIYGA"
                     /locus_tag="M1F92_RS09530_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       3077..3214
                     /prepeptide="core"
                     /locus_tag="M1F92_RS09530_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class II"
                     /score="-0.40"
                     /molecular_weight="4357.9"
                     /monoisotopic_mass="4355.3"
                     /core_sequence="SDGAEPRWTPTPLILKSAAASSKVCISALVSGIGGLVSYNNDC
                     LG"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MTNFNSNEKFCGKSLKSLSADEMSLIYGA"
                     /leader_location="[2989:3076](+)"
                     /alternative_weights="4375.9"
                     /alternative_weights="4394.0"
                     /alternative_weights="4412.0"
                     /alternative_weights="4430.0"
                     /alternative_weights="4448.0"
                     /alternative_weights="4466.0"
                     /alternative_weights="4484.1"
     gene            3221..3409
                     /gene="pneA2"
                     /locus_tag="M1F92_RS09535"
     CDS             3221..3409
                     /codon_start=1
                     /gene="pneA2"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000786759.1"
                     /locus_tag="M1F92_RS09535"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="two-peptide bacteriocin subunit PneA2"
                     /protein_id="WP_000786759.1"
                     /transl_table=11
                     /translation="MKNDFVIGKSLKELSLEEMQLVYGGTDGADPRSTIICSATLSFIA
                     SYLGSAQTRCGKDNKKK"
     CDS_motif       3221..3295
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence: MKNDFVIGKSLKELSLEEMQLVYGG"
                     /locus_tag="M1F92_RS09535_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       3296..3409
                     /prepeptide="core"
                     /locus_tag="M1F92_RS09535_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class II"
                     /score="-1.30"
                     /molecular_weight="3743.2"
                     /monoisotopic_mass="3741.0"
                     /core_sequence="TDGADPRSTIICSATLSFIASYLGSAQTRCGKDNKKK"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MKNDFVIGKSLKELSLEEMQLVYGG"
                     /leader_location="[3220:3295](+)"
                     /alternative_weights="3761.2"
                     /alternative_weights="3779.2"
                     /alternative_weights="3797.3"
                     /alternative_weights="3815.3"
                     /alternative_weights="3833.3"
                     /alternative_weights="3851.3"
                     /alternative_weights="3869.3"
     gene            3528..6518
                     /gene="lanM"
                     /locus_tag="M1F92_RS09540"
     CDS             3528..6518
                     /GO_process="GO:0009403 - toxin biosynthetic process
                     [Evidence IEA]"
                     /GO_process="GO:0018193 - peptidyl-amino acid modification
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="lanM"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-ii: LANC_like"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-ii: DUF4135"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1070: lanthionine synthetase C family protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000875571.1"
                     /locus_tag="M1F92_RS09540"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="type 2 lanthipeptide synthetase LanM"
                     /protein_id="WP_247933250.1"
                     /sec_met_domain="DUF4135 (E-value: 7.2e-92, bitscore:
                     298.0, seeds: 79, tool: rule-based-clusters)"
                     /sec_met_domain="LANC_like (E-value: 1.2e-52, bitscore:
                     168.5, seeds: 47, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKYKIKNVHKTLFIKERYQILSERNDNSLNNFSLNNWRSTMSIIS
                     EKTFEEMLKLNNYNKKIFSNTVNYDYTEEQIRLYSEYAENSEWYKFAEGSFEIFRKHPQ
                     RINFKKDFSRILEPFIINLLKLINNYLDNKEYEWVDKNGNILSSLVFYLEDLIYPWIVK
                     PLVLEINSLREKGLLEGESEQQRYKYFITLLDKEEHLLNFYNKYPVLLRQISESCLRFY
                     TYFIEILSNLENDFSVLEEEFGLRGKLNDIKFGKGDTHSEGKTVLILFFDDAKIVYKPK
                     NLIINNSLNTIAEYIRKVDEKIRIRIPRTIAYSDHSYEEFIDYLPLEQKKKLPEYYYNF
                     GVLLAFIYLFNGSDIHFENLISYGDMPVVIDFETMLQQPLFDDKTAQSLLDILFHRVTR
                     TLLLPTEGVKREDGLDVEMSALTGSFKKDAFNGQVLINLNTDKVKFDIGKIDFEGGKNL
                     PIRDGDIDFDKYIKDFKRGFRDFYLIFEELNKTEEFKMLLKANLYGLKTRVLFRDTNSY
                     ASVLSFLYHPDFYEEMLDREKALENLWSNKFSNQGIVASECEQMRLLDIPIFYTDTHFN
                     EIYDDFGNHFISLHQFSGYDYFMKYLPNNNLEDLEKQLDIIEIYFPSFNQRKKGYKLNI
                     SNRKKLQNESLLTILHNEVENIADSLVINNIYDEYPIWSIPVNFKDSKWCLEQTGNDMY
                     RGRAGILLFMYYVKLLKDKSSYTQLYNKMLSAIPPSVSLSKTTFGLTGDLGYFIVLSII
                     EDYDTNTLACLNYIKSVLTELEKTNFASVSNKSDYINGLLPLINTLIRYYRRGIERERV
                     LRLVLSLGDTLYNDVSERDNSNFGYSFGHGLSGVIFTLKNIYKETRLKKYKELILQLVP
                     REKVQIHSLKWCSGEFGTLVNYPQSVPEEIVASLDNDTFCHGSMAIINFYIDFMKEMDT
                     SMELESLLCSVIMNKSKEGEYRIVQTSNFPDFSLYTGVTGIAYTFLRYIALNQNDKKIV
                     IPSLLEI"
     gene            6696..7400
                     /locus_tag="M1F92_RS09545"
     CDS             6696..7400
                     /GO_function="GO:0009055 - electron transfer activity
                     [Evidence IEA]"
                     /GO_function="GO:0010181 - FMN binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001033172.1"
                     /locus_tag="M1F92_RS09545"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="flavodoxin family protein"
                     /protein_id="WP_033607257.1"
                     /transl_table=11
                     /translation="MNKIFIYAGVRNRNSKTLEYTKRLSSIISSRNNVDISFRTPFNSE
                     LEISNSDSEELFQKGIDRQSDADDGGIIKKELLDSDIIIISSPVYLQNVSVDTKNFIER
                     IGGWSHLFRLAGKFVVTLDVSESNGSDNVSEYLRDIFSYMGGQILHQVSITNSLKDIAE
                     AQLMEATYKIEDVLEGKIKYKTTDYQERAYQTLKLILENYDSEHFEKIYWEKKCLFEAN
                     SLEEWYYVKNIK"
     gene            7381..8310
                     /locus_tag="M1F92_RS09550"
     CDS             7381..8310
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_M50"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000912951.1"
                     /locus_tag="M1F92_RS09550"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="M50 family metallopeptidase"
                     /protein_id="WP_033607259.1"
                     /sec_met_domain="Peptidase_M50 (E-value: 1e-09, bitscore:
                     27.6, seeds: 56, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLKILNNSVIYLCLAPLLFLLLIFFPNDSLIYFFRLILITLISIT
                     LHELGHFLVGRCLSYKLEMLATPFFFYFRKKMYFKFPVLLAFGYCQMSNRNITNEKNSD
                     RNLVFYFFGGGGANLIVAILALLGFVPYTSEFFILNIILFIVTVCLPIDGTDGNAIREI
                     VLYSKDSKTYQRFFANSLYNNPYITIDDFAKLTSKEKSFFSKFEKCLINLYFEVKGEGS
                     AFTIANHEVFDSNIQENIIHEYYKLLHKSSDWIIPQNLSLEEVVFTLSNYIYSKNNKYL
                     EKIKYLKKLVDFRQEEIIDFILNKEEVL"
     gene            8307..10415
                     /locus_tag="M1F92_RS09555"
     CDS             8307..10415
                     /GO_component="GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0008233 - peptidase activity [Evidence
                     IEA]"
                     /GO_function="GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_C39"
                     /gene_functions="transport (smcogs) SMCOG1288: ABC
                     transporter related protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000701297.1"
                     /locus_tag="M1F92_RS09555"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="peptidase domain-containing ABC transporter"
                     /protein_id="WP_000701298.1"
                     /sec_met_domain="Peptidase_C39 (E-value: 2.7e-39, bitscore:
                     123.7, seeds: 36, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKIPMIYQMENSECGLACCAMILNYFKYEISLNELREIYPSSRSG
                     YSLLSISKVLGDFNISSHAFKASVRDLKPLSFPLICFWESSHFIILEKISKNKFYILDP
                     AKGRQRMSISEFERHYSNIILTFKKLDSFMSRKDNKKSPVLKYFFKYRNKLGILFFVTA
                     LLYVIQSLVPIANRYIIDTNFKDDSYSSRMLFTILFIFTVSFSLMYLLRQIYVASLKYI
                     MDKEISYDFMKHLIYLPYSFYEKRTLGDILFRANSIVYIREILSNNFIAAILDLLMIVV
                     YAVVLFSFSKYMVIFLISLSLALSIVMYPIIKISKNLIDKNIKEKVNVQNITSEVISKN
                     SDIKLTGEEEFWINKWDNFNTKQLIIGRKLDIHLSIVSSITNVLQIILPVLTLIVGVNI
                     KTFEQLTLGQIVAISTVSPYFISPIISLSDNYIQLMLLKGYFLRIEDVFNTKSELIPER
                     VSQDIKFDKKIELKDIWYKYGLFDDYVLKGINVTIKKGETVAIVGESGSGKSTLAKILL
                     GLLEPNIGSIEVDGVEKEEIGQTLYRKIFGAVLQNSTLSYGTLRENLTFGHFVSDEELM
                     TNLNSIGLSNVVKSLPLGLETIIAEEGNNFSGGQQQMILLARCLLSKPSVVVLDEATSS
                     LDNLSQQITTSYLSEIGTTKILIAHRLDTIKSADKILVMHNGEIVEIGTHRELLELGGI
                     YKQLYSNN"
     gene            10439..12178
                     /locus_tag="M1F92_RS09560"
     CDS             10439..12178
                     /GO_function="GO:0008236 - serine-type peptidase activity
                     [Evidence IEA]"
                     /GO_process="GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_S8"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1075: alkaline serine protease, subtilase family"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000699970.1"
                     /locus_tag="M1F92_RS09560"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="S8 family serine peptidase"
                     /protein_id="WP_247933251.1"
                     /sec_met_domain="Peptidase_S8 (E-value: 2.9e-40, bitscore:
                     128.0, seeds: 43, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKIMKKKYWTLAILFFCLFNNSVTAQEIPKNLDGNITHTQTSESF
                     SESDEKQVDYSNKNQEEVDQNKFRIQIDKTELFVTTDKHLEKNCCKLELEPQINNDIVN
                     SESNNLLGEDNLDNKIKENVSHLDNRGGNIEHDKDNLESSIVRKYEWDIDKVTGGGESY
                     KLYSKSNSKVSIAILDSGVDLQNTGLLKNLSNHSKNYVPNKGYLGKEEGEEGIISDIQD
                     RLGHGTAVVAQIVGDDNINGVNPHVNINVYRIFGKSSASPDWIVKAIFDAVDDGNDIIN
                     LSTGQYLMIDGEYEDGTNDFETFLKYKKAIDYANQKGVIIVAALGNDSLNVSNQSDLLK
                     LISSRKKVRKPGLVVDVPSYFSSTISVGGIDRLGNLSDFSNRGDSDAIYAPAGSTLSLS
                     ELGLNNFINAEKYKEDWIFSATLGGYTYLYGNSFAAPKVSGAIAMIIDKYKLKAQPYNY
                     MFVKKILEETLPVKNGIKVLNIPNVLKYDLNMLQSEYKNEQSWDSFIDNVNLIELEKRI
                     QTTIEIKQINTRNIITIAREEYSQNYLPNTSENTYNSLQVSLVGVLLLFISMVNILWAQ
                     KSK"
     gene            complement(12292..13558)
                     /locus_tag="M1F92_RS09565"
                     /pseudo=""
     CDS             complement(12292..13558)
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1206: transposase"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000436304.1"
                     /locus_tag="M1F92_RS09565"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /product="transposase"
                     /pseudo=""
                     /transl_table=11
                     /translation="MEQLHFITKLLDIKDPNIQIIDVINRDTHKEIITKLDYDAPSCPC
                     CGSLMKKYDFQKTAKIPYLETTGMPTRILLKKRRFKCYQCSKTAVAETSLVKKNHQIPR
                     IINQKIAQKLIGKTSMTDIAHQLSISTSTVIRKLNDFRFKHDFSRLPKIMSWDEYAFTK
                     GKMSFIAQDFDNLNIITVLEGRTQAVIRNHFLRYDRAFRCKVKIITMDMFNPYYVLAKQ
                     LCFLISRLRLKQSTGLFYSNI"
     misc_feature    complement(14092..14108)
                     /note="TFBS match to GnfM, Regulator of nitrogen-fixation
                     genes, confidence: medium, score: 21.63"
                     /tool="antismash"
ORIGIN
        1 ataccgttcg tgaatttgaa gtggaacttg cagagaacca aatagagaag ctagttgatg
       61 agggcattta tatcaaaatg tcttttggta ttaatcagag tggtctcatt ttcattccaa
      121 attatcaatt agatattctg gaagaagaga atcaaacaaa atataaaatc tttatacgtg
      181 agacaacctc atactttgta tataacaaag aacattcgga taagaatcag tatgtcaaag
      241 gacgaacatt gataagacag ctaaccaacg atagtcgagt aataccatac agaagaccta
      301 cagttaagag tctacaggaa aagattactg agattaacct cttcattgaa ttaactgaag
      361 tagataagaa ataccaagac attaaagacg agttagtaaa agaaatagca gagatagata
      421 taaaactaaa tcaaattaat gaaaaaatcg ccaacttaaa taagatggcg gaagtgctta
      481 tcaatttgaa gagtgaggat gtgagcagtc gaaagcttgc aagatatgac ttttcaaaac
      541 tgaacttgac agaatcaact tcattagaac aagtgactga agaaataaga gcattgcaag
      601 aggaactagg tcaccatatt ggtgagtatg agagactcat aaaaagatta gaaacatttg
      661 taaaaatgtt gaatactggt aaaggcgtta atcaaaaatt tgatatggag atttcattac
      721 agtaatagaa atgctggcaa tgtaactatc tcgacatttt aaatttattt tatagatatt
      781 taatgacaaa taatatgctt attctcgtca atttataatg ataatgctga attaattcag
      841 actgccagag agaaaggaca gcgagtgagg tgcccatgag gtcattatct ttgagtttgc
      901 caataatcta ttgtttagag atgtcaaaaa cggtaagaat atgcaaaacc tcatcgcagc
      961 attattattc ttatcaataa tcatcagcca taaattattt tcatcaatta attgtttgga
     1021 taaaagaaag ttcagacctc aatcgttaca tgagagggcg tgaactaatc cgtcaactta
     1081 ctcacgacag cacgcatatc cctagacgta ggcgaccaac cattgccaac ctcaaagaga
     1141 aaatcgcgga ggtgaatctt cttatcgaat tagactttaa caatcagtct taccagtaaa
     1201 tcaaagatga gttaatcaag gaaatcgccc agctggattt gaccattaca gatttgcagg
     1261 ataaactagc tcatcttaat aaggtagcag aagtactaat taatctcaat aattctggcc
     1321 cagaaaatag aagattggca aaatatgatt atgctaagat gaacatgacg tcagccatta
     1381 aaatggagca ggtggagaaa gagattgaag aaaatcaaaa atccatgatg aaatcgatag
     1441 atgattacga atataagatt aggagactgg agaattttat caacatactt gataacacag
     1501 ggcgtcaaaa tatcaccaat ttagaacacg aaaataaatc aatctagttg tttgagatac
     1561 cacagaaaaa ttataagact gatagtatta atttcactat cagtcttaca ggttatttaa
     1621 ggttcaggta gaactccaat atcaagataa attaaaaagt atctaattcc tttaaataat
     1681 tttctatctt cataagcatt aaaggattat tatagatctt gcataattcc cttgcttcta
     1741 tataataatt tttgacttgt tctttatcta gaaattgttc tccagcattt ccgacgagta
     1801 tgagtagggg agctaattgg tagcttgttt gtcgcttttt acagagttca atcgtttcaa
     1861 gagcttcttg gatagcttcg ttatgttttg cctttgacac taaatagtga gcgtagttgt
     1921 aacgaactct gatgtaacca aataaaaact cttgataatc cagatttttt gtctgataca
     1981 actccattaa gtgaaagtag tttgcttcat attcttgttc acggtccact aaggaataga
     2041 aattagatag agtattcatt acctttaagt aaatcagagt atttgaggat acttttgata
     2101 atatattttc caaataagaa atagcctcat acttgtggtc atattgatag aagtcaataa
     2161 tagcttttat ccattcaaga tacatcttgt cttctagtgt tagaaaattg tttcgctcta
     2221 actctatctt ataaagatat tctaaatctt tataatttct atcttctagt agacgagaag
     2281 ataaattctt gaagttagat aggttagatt ttacttcaat ttgttcattg aaaaagtaat
     2341 ccaacgggac ctcaagtcgt tgagagagtt tgaacaaaag gtctgcggag ggaataaaac
     2401 gccctctctc aatcttgctg atctgacttt gttcacaaat tccttctgca agagtttgtt
     2461 gggaaagtcc cagttctttt cttttagttc tgaatttttc ggagagtata ttcattaaaa
     2521 aacagtaatc ctttcaactt atttaagtta attataattt ttttagttca aaatagcaat
     2581 tattaagatc tatttattct ttttaggaat ataaaagaaa aaaattccaa aaataaataa
     2641 aaactcttga ctttatgaga tatatcagtt aaaataaagt caaggaaaaa gaaagggctt
     2701 tcattacatg agaaaaaaac gtggaattaa tcagttgatg gcattcttat tgttaggttc
     2761 tatcgcattt agcaacgtct ttttttacag acaaccgaat ccgaaagata cttcagcctt
     2821 ctcttatgaa gtgaggatag gagtacaaaa taaatccagt ggtcttgatg taggtaaggc
     2881 agattaaaac ccggtatttt gcacgagaat gatagagtta taatttatct aaaaaaacaa
     2941 aaaatataga gcaacttatt taacttttta taaggaggag ttattactta tgaccaactt
     3001 taattcaaac gaaaaatttt gtggaaaaag tttaaaatca ttgtctgctg atgaaatgag
     3061 tttaatatat ggtgcatctg atggtgcaga gccacgttgg acgcctactc ctttaatttt
     3121 gaaatcagct gcagctagct cgaaagtatg tattagtgca cttgtttctg gtattggggg
     3181 gctagttagc tacaataatg attgtttggg gtaaattaaa atgaaaaatg attttgtaat
     3241 cggaaagagt ttgaaagaat tatcccttga agaaatgcaa ttggtttatg gtggcacaga
     3301 tggtgctgac cctagatcaa caattatatg ttctgctaca ttaagtttta ttgcatcata
     3361 tttgggttca gctcagactc gttgtggcaa agataacaag aaaaaataaa atattcaatt
     3421 ttaaaaaata aaagttgctc tttattttcc tctctcgtaa ctaataattt tgagagaggt
     3481 tttttattaa aaaacaatag taagtcgtat aggttggagg taagtaaatg aaatataaaa
     3541 ttaaaaatgt gcataaaaca ttgtttatta aggaaagata tcaaatatta tctgaacgaa
     3601 atgataattc cttaaataac ttttcattaa ataattggcg ttctacaatg tcaattattt
     3661 ctgaaaaaac ttttgaagaa atgttgaaat taaataatta caataaaaaa atattttcta
     3721 acactgtgaa ctatgattat actgaggaac agataagact atattcagaa tatgctgaaa
     3781 attcggaatg gtataaattt gcggagggtt catttgaaat atttagaaaa catccccaaa
     3841 gaattaattt taagaaagat ttttctagaa ttttggaacc ctttattatt aatttgctta
     3901 aattaatcaa taattatcta gataataaag aatacgagtg ggttgacaag aatggaaata
     3961 ttctttcctc tctagtattt tatttagaag atttaatcta tccttggatt gttaaacctt
     4021 tggttttaga gataaattca ttgcgtgaaa aaggtttgct tgaaggggaa tcggagcagc
     4081 aacggtacaa atattttata acattgcttg acaaggaaga gcatctatta aatttttata
     4141 acaaatatcc cgttttattg aggcaaatat cggagtcttg tcttcggttc tatacttatt
     4201 ttatagaaat tttatcaaat ttagaaaatg attttagtgt attagaagaa gaatttgggc
     4261 taagggggaa attaaatgat ataaaatttg gaaagggtga tacacacagc gaaggaaaaa
     4321 cggttttgat actcttcttt gatgacgcga aaattgttta caagcctaaa aatttaataa
     4381 tcaataactc actaaatact attgctgagt atatccgaaa ggttgatgaa aaaattagga
     4441 taagaatacc tcgaactatt gcttattcgg atcacagcta tgaagaattt attgattatc
     4501 tacctctaga gcaaaagaaa aaattacctg aatattatta taatttcggt gtgcttttag
     4561 catttatata tttatttaat gggagtgata tacattttga aaatttgatt tcctatggag
     4621 atatgcctgt agtaatagac tttgaaacaa tgttacagca acctctattt gatgataaaa
     4681 ctgctcagag tttgctggat attctgtttc acagggtgac tcgaactttg cttcttccaa
     4741 cagagggagt gaaaagggag gatggtcttg atgttgagat gagtgctctt acaggaagtt
     4801 ttaagaagga tgcttttaat ggtcaagttt taattaattt aaatactgat aaggtaaagt
     4861 ttgatattgg gaaaattgat tttgaaggtg ggaaaaacct ccctattcgg gatggtgata
     4921 tagattttga taagtatata aaagatttca aaagaggttt tagggatttt tatctgatat
     4981 ttgaagagtt aaataaaaca gaagaattta aaatgctatt aaaagcaaac ttgtatggtt
     5041 taaagacaag ggtacttttt agagatacaa atagctatgc ttcagtacta tcttttttat
     5101 atcatcctga tttttatgaa gaaatgttag atagagaaaa agcattggaa aatctctgga
     5161 gcaataagtt ttctaatcaa ggtattgtag caagtgaatg tgaacaaatg aggttattag
     5221 atattccgat tttttataca gatacacatt tcaacgaaat ctacgatgat tttggaaatc
     5281 attttatttc cctacatcaa ttttctggat atgactattt tatgaaatat ttacctaaca
     5341 ataatttgga agatttagaa aagcaacttg atatcattga aatttatttt ccaagcttta
     5401 atcagcgaaa aaaaggatac aaattaaaca tatctaatag aaaaaaactc caaaatgaaa
     5461 gtttacttac aattctgcat aatgaagtag agaatattgc agactctttg gttattaata
     5521 atatttatga cgaatatcca atttggagta tacctgttaa ttttaaagat tcaaaatggt
     5581 gtcttgaaca aacgggtaat gatatgtata gggggagagc tggaatacta ctgtttatgt
     5641 actatgtaaa attattgaaa gataaatcat catatactca actgtacaat aaaatgttat
     5701 ctgcaattcc gccatctgtt tctttatcta agaccacatt tggtttaact ggtgatctag
     5761 gatatttcat tgttctatcc attatagagg attacgatac aaatactctc gcatgcttaa
     5821 attatataaa gagtgtttta actgagcttg aaaagactaa ttttgcaagt gtttcaaaca
     5881 agtctgacta tattaatggt cttctacctt taattaatac actgataaga tattatagga
     5941 gaggaataga gagggaacgt gttctaaggc tagtattaag tttaggtgat acgctatata
     6001 atgatgtaag cgagagagat aatagtaatt ttggatatag ttttggtcat ggactatcag
     6061 gtgtaatttt tacattgaaa aatatttata aagagacaag acttaaaaaa tataaagaat
     6121 taattttaca actagttcct agggagaaag tccaaattca ttctttgaag tggtgtagtg
     6181 gagaatttgg gacattagtt aattatcccc aaagtgttcc agaggaaatt gtagctagtt
     6241 tagataatga tacattttgc catggaagta tggccataat aaatttttac atcgacttca
     6301 tgaaagaaat ggacactagt atggaattgg agtctttatt gtgtagtgtt ataatgaata
     6361 aatcaaaaga aggagagtat cgtatcgtcc aaacaagcaa ttttccagat ttttctttgt
     6421 atacaggtgt cactggtatt gcttatactt ttttaaggta tatcgcactg aatcagaatg
     6481 ataaaaagat agttatcccc tcattacttg aaatctagct taatttatag ttttgtttct
     6541 aaaattgagg tgttcactta ttaagtaata taaaaatacc aagattgact agtttaatac
     6601 aaaacatatg taataatgtg agccaacaaa agtctgtttt tgaaccatac tatcttgaaa
     6661 aatctactaa attcaaattg agaggatgaa ttaaaatgaa taaaatattt atatatgcag
     6721 gagtgcgaaa tcgtaactct aagactttag agtatactaa gagactttca agtatcattt
     6781 ctagtagaaa taatgttgat atatctttca ggacaccttt caattcagag ctagaaatat
     6841 ctaattctga ttcagaagag ttgtttcaga aaggaattga taggcaaagt gatgctgatg
     6901 atggaggcat tataaaaaaa gagttattag actctgatat tataattatc tcttctcctg
     6961 tatatttaca aaacgtatct gtggacacta aaaactttat tgaaaggatt ggggggtgga
     7021 gtcatctttt tcgattagct ggaaagtttg ttgtaacatt agatgtttct gagagtaacg
     7081 gctctgataa tgtgtcagaa tatcttagag atatattttc atatatggga ggacagatct
     7141 tacaccaagt ttcaattacc aattcactca aagatattgc agaggctcag ttgatggagg
     7201 caacttataa aattgaagat gtacttgaag ggaaaattaa gtacaaaaca acggattatc
     7261 aagaaagagc ttaccagaca ttaaaattaa ttttagaaaa ttatgattcc gaacattttg
     7321 agaagatata ttgggagaaa aaatgccttt ttgaagctaa tagtttagag gaatggtatt
     7381 atgttaaaaa tattaaataa ctctgtcata tatttatgtt tggcgccgtt attattccta
     7441 ttattgatat tttttccaaa tgattcatta atctattttt ttcgattgat tttaattacg
     7501 ttaatatcaa ttacattaca tgaactaggt cattttttag tgggaagatg tttatcttat
     7561 aaactagaga tgcttgctac tccctttttc ttctatttta gaaaaaaaat gtatttcaaa
     7621 tttccagtgt tattagcatt cggttattgt caaatgagta atagaaacat tactaatgaa
     7681 aaaaatagtg ataggaattt ggtgttctac ttctttgggg gaggtggagc taacctaatt
     7741 gtcgcaatat tagcactttt gggatttgtg ccgtacacat cagaattttt tattttgaat
     7801 ataattcttt ttatagtcac ggtatgttta ccaattgatg gaacagatgg caatgctatt
     7861 agagagatag ttttgtattc aaaagattca aaaacatatc agagattctt tgcgaacagt
     7921 ctctataata atccttatat aacaatcgac gattttgcaa aattaacctc taaagaaaaa
     7981 tctttttttt caaaatttga aaaatgtttg ataaaccttt actttgaagt gaaaggtgaa
     8041 gggtcagcat ttacaattgc taatcatgaa gtttttgatt caaatattca ggaaaatatt
     8101 atccatgagt actataaatt actacataaa tcttctgatt ggattattcc acagaactta
     8161 tctttagaag aagttgtttt taccttgtca aactatattt actcgaaaaa taataaatat
     8221 ttagaaaaga ttaagtatct aaagaaatta gtagatttta gacaagaaga aattatcgac
     8281 tttattttga acaaggagga agtattgtga aaattccaat gatatatcaa atggaaaatt
     8341 cagaatgtgg attagcatgc tgtgccatga tattgaacta ttttaaatat gagatttctt
     8401 taaatgaact acgtgaaatc tacccatcat ccagatctgg atattctctc ctatctataa
     8461 gtaaagtttt aggagatttt aatataagtt ctcatgcttt taaagcttcg gtaagagatt
     8521 taaaaccgct cagtttccca ctcatttgct tctgggagag ttctcatttt attattcttg
     8581 aaaaaattag taaaaacaag ttttatattt tagatcctgc aaaaggcagg cagagaatgt
     8641 caataagtga atttgaaagg cattattcaa atatcatttt aacatttaaa aagttagata
     8701 gctttatgtc tcgtaaagat aataagaagt cgcctgtttt aaagtatttt tttaagtata
     8761 ggaataagct agggatttta ttttttgtaa cagcattatt gtatgtaata caatcattag
     8821 tacctatagc taatagatac ataattgaca cgaatttcaa ggacgattcg tattcgtcta
     8881 gaatgttatt tactatatta tttatattta ctgtttcatt ctcactaatg tatttattaa
     8941 gacagatata tgttgcatcc ttaaaatata taatggataa agagattagc tatgatttta
     9001 tgaaacattt gatatattta ccttacagtt tttatgaaaa acgtacttta ggggatatac
     9061 tttttagagc taactctatt gtttatataa gagaaatact atcaaataat tttatagcag
     9121 ctatacttga tttgttaatg attgtggttt atgctgtggt tttatttagc ttttctaagt
     9181 acatggtgat ctttttaata tcactaagtc tagctctatc tattgtaatg tatccaatca
     9241 taaaaatctc aaaaaattta attgataaaa atataaaaga aaaggttaat gttcaaaata
     9301 ttacttccga agtaatttct aaaaatagtg atattaagct aactggagaa gaggaatttt
     9361 ggattaacaa atgggataat tttaatacaa aacagctcat cataggtcga aaacttgata
     9421 tacatttatc aattgttagt agtataacga atgttttaca aattattctc cctgttttga
     9481 cccttattgt aggtgtaaat ataaaaacat tcgaacaatt gacgttagga caaattgtag
     9541 caataagtac agtctcacca tactttattt ctcctataat ttctttaagt gataactata
     9601 tacaattaat gttattaaag ggatattttt taagaataga ggatgtgttt aatactaaat
     9661 ccgaattaat tccagaaaga gtcagtcaag atataaaatt tgataaaaaa atagaattaa
     9721 aagatatttg gtataaatat ggattatttg atgattatgt tttgaaagga ataaatgtta
     9781 ctattaaaaa aggagaaact gttgctattg ttggagaatc aggttcaggt aagagtacat
     9841 tagctaaaat tttattaggt ttattagaac ctaatattgg ttcaatagaa gttgatggag
     9901 tagaaaaaga agaaattggt caaacattgt atagaaagat ttttggagca gtgttacaaa
     9961 attcaaccct aagttatggt accttaagag agaatttgac atttggacac tttgtttcag
    10021 atgaagaatt aatgacaaat ctaaattcaa ttggtcttag caatgtagtt aagtctttac
    10081 ctcttggatt agagacaatc atcgctgaag aaggtaataa cttttctgga gggcagcagc
    10141 aaatgatact tttagctcgt tgtcttttgt cgaaaccttc ggtagttgtt ttggacgaag
    10201 caacaagtag tttagataat ttatctcaac aaattacaac ttcttactta agtgaaatcg
    10261 gtaccactaa gattttaatt gcccatcgac tagatactat caagtctgca gataagatct
    10321 tagtaatgca taatggtgaa attgtagaga ttgggaccca tagagaactt cttgaactag
    10381 gaggcattta taagcaattg tattcaaata attagttttt gattaaaagg gtaaatttat
    10441 gaagattatg aaaaaaaaat attggacttt agcgatatta ttcttttgtt tgttcaataa
    10501 ttctgttact gctcaagaaa tacctaaaaa tcttgatggc aatataactc acactcagac
    10561 tagcgaaagt ttttctgaat ctgatgaaaa acaggttgac tattctaata aaaatcaaga
    10621 agaagtagac caaaataaat ttcgtattca aatcgataag acagaattat ttgtaacaac
    10681 agataaacat ttagaaaaaa actgttgtaa attggaactt gaaccacaaa taaataacga
    10741 tattgttaac tctgaaagta ataatttact aggcgaagat aatttagata ataaaattaa
    10801 ggaaaatgtt tctcatctag ataatagagg aggaaatata gagcatgaca aagataactt
    10861 agaatcgtcg attgtaagaa aatatgaatg ggatatagat aaagttactg gtggaggcga
    10921 aagttataaa ttatattcta aaagtaattc taaagtttca attgctattt tagattcagg
    10981 agtcgattta caaaatactg gattactgaa aaatctttca aatcactcaa aaaactatgt
    11041 ccccaataaa ggatatttag gaaaagagga gggagaggaa ggaataatat cagatattca
    11101 agatagatta ggtcatggta cggctgttgt agctcaaatt gtaggggatg acaatattaa
    11161 tggagtaaat cctcacgtta atattaacgt ctatagaata tttggtaagt cgtcagctag
    11221 tccagattgg attgtaaaag caatttttga tgctgtagat gatggcaatg atattatcaa
    11281 tcttagtact ggacaatatt taatgattga tggagaatat gaggatggaa cgaatgattt
    11341 tgaaacattt ttgaagtata aaaaggctat tgattacgcg aatcaaaaag gagtaattat
    11401 agtagctgca ttagggaatg actcgctaaa tgtatcaaat cagtcagatt tattgaaact
    11461 tattagttca cgcaaaaaag taagaaaacc tggattagta gttgatgttc caagttattt
    11521 ctcatctaca atttcggtcg gaggcataga tcgcttaggt aatttatcag attttagcaa
    11581 tagaggggat tctgatgcaa tatatgcacc tgcaggctca acattgtctc tttcagaatt
    11641 aggacttaat aactttatta atgcagaaaa atataaagaa gattggattt tttcggcaac
    11701 actaggagga tatacgtatc tttatggaaa ctcatttgct gctcctaaag tttctggtgc
    11761 gattgcaatg attattgata aatacaaatt aaaagctcaa ccatataatt atatgtttgt
    11821 aaaaaaaatt ctggaagaaa cattaccagt aaaaaatggt ataaaagtgt taaatatacc
    11881 aaacgtattg aaatatgatt tgaatatgct acaatcagaa tataaaaatg aacaaagttg
    11941 ggatagtttc atagataatg ttaatttaat tgagttggaa aagagaattc aaactactat
    12001 tgaaattaaa caaataaaca cacgtaatat tattactatt gcccgagaag agtactctca
    12061 aaattattta cctaacactt cagaaaatac atataattca ttacaagtca gtttagttgg
    12121 agtattacta ctttttataa gtatggtaaa tattttatgg gctcaaaaaa gtaaatgaaa
    12181 ataaaatttg gagctttctg aaaaagtaag tcctacagtt caactaaaat gagtcaaaag
    12241 aggaatctat ctcataagtc tctttgtcaa ctgtagtggg ttgaagaaaa gctaagacct
    12301 agaaaggaca aatttcgtcc tttctttttt gatgttcaga gcgataaaaa ttcgtttttt
    12361 gaagttttca aagtttcgaa aaccaaagtc atttcgcttg ataagttcga taagattatt
    12421 ggtcgtttcc aatttggcgt tagaataggg tagtagaagg tcattgacaa tcttctcttt
    12481 atctttcaga aattttttaa agacagtctg aaatagagga tgaacctgct ttagattgtc
    12541 ctcaatgagt tcaaagaatt tctctggttc cttattttga aagtgaaaaa gcaagagctg
    12601 atacagctga tagtggtgtt ttaagtcttc tgaacagctc aaaagcttgt ctaggatttt
    12661 ttattggtta agtgcatacg aaaagtagaa cgataagaac atttatcgct gagtttccga
    12721 ctatcttgtt gaatgatctt ccggtagcgc ttgatagcct tgtattcatg ggattttcga
    12781 tccaattgat tcatgatttg ggtacgcaca cgactcatag cacggcttag atgttagagt
    12841 aaaacagtcc agtggactgt tttagcctga gcctagaaat tagaaagcaa agctgtttag
    12901 ccaagacata ataaggatta aacatatcca tagtaatgat tttcacctta catcgaaatg
    12961 ctctatcgta gcgaagaaag tgatttcgga tgacagcttg tgtcctgcct tcaagaacag
    13021 tgatgatgtt gagattatca aaatcttgtg caatgaaact catctttccc ttggtaaagg
    13081 cgtactcgtc ccaggacata atctttggta gacgagaaaa atcatgctta aaacggaagt
    13141 cattgagctt gcgaataaca gttgaggttg agatggaaag ttgatgagca atgtcggtca
    13201 tagaagtctt tccaatcaac ttttgagcaa tcttttgatt gatgatacga gggatttggt
    13261 gatttttctt gacgagggaa gtttcagcga cagccgtttt tgagcactga tagcacttaa
    13321 aacgccgttt tttaaggaga attctagtag gcataccagt tgtctcaagg taaggaattt
    13381 tcgccgtttt ttgaaagtca tatttcttca ttagacttcc acaacaaggg caagatgggg
    13441 catcgtagtc tagtttagtg atgatttctt tgtgggtatc cctattaatg acatcaataa
    13501 tttgtatatt agggtcttta atgtctagta attttgtgat aaaatgtaat tgttccatat
    13561 gaatctttct aatgagttgt tttgtcgctt tttattatag gtcatatggg acttttttct
    13621 ataacaaaat aggctcaata atattcatag gggatttacc cactacatat attatagagc
    13681 ctttaatcct ttcaagctgt ttgagtcaac tcaagcagct ttttcgagta cttataccca
    13741 ttaatttttc taggctttcg ttaaatattt ttgtactatc ctctataaaa tcttatttca
    13801 attctttgag tgaatttgct tttgaaatga agtcacgtaa aggagtgatg aagttctcat
    13861 cgaatgtatg accataggat gaataggtac gggcaaaata aatttttaat acctcctatt
    13921 taatcgagta aagaaaactc gatttcatta tcagtagtaa tgatttgatt acataccgtt
    13981 tcttgcgtta tgacacatct tgattgacat attctacctt cttatctaag agtttacttg
    14041 agatagcata gcaagtttgt cactctcctg agatcagaat agaaggttca ctgaccgtat
    14101 tttaagcaat aacagaatct agttcacaat atcagaaacg tatccaatta ttaatttctt
    14161 ctgctccatc ataaattttt atctcctagt tgtttttagg agatatagtc ttagtagatt
    14221 tattaaaaag ttgtacaaca ctgggtaatt caataaactt ttcttgatgc atatagttat
    14281 aaaacatctt ggttaaagaa acaactgaat caaaatgttg gaatttataa gtgtgaacga
    14341 aagttttcaa actatctccc cttggttttt ctttcatcgc ttatgtgaat tctgtcagaa
    14401 agtcaggcta aatcttattt agtttataag taatagctaa cttctataga atgataatgc
    14461 aaattctaga ttggatttgc ataatactgt tatcagtata tcttctatca attgatttgt
    14521 ttcacctgtg ttacagaatc ttgattagtt ttacaagtaa aaatagaacg gtttctatcc
    14581 taacgacgag cagtctaagc tgtttttttc ctttgtttaa ataaaactaa aatttagtat
    14641 tgttcagctt ctgagaagtg cttgtatgat tgatttgtga acatttttct ataattttgt
    14701 aatatttttg agactataat atatcagata aacatgtctt ttgtgtttca ctttatttta
    14761 aaata
//
