LOCUS       NZ_JALMDK010000009     22576 bp    DNA     linear   CON 13-SEP-2024
DEFINITION  Crossiella sp. S99.2 NODE_9_length_405922_cov_169.235131, whole
            genome shotgun sequence.
ACCESSION   NZ_JALMDK010000009
VERSION     NZ_JALMDK010000009.1
KEYWORDS    WGS; RefSeq.
SOURCE      Crossiella sp. S99.2
  ORGANISM  Crossiella sp. S99.2
            Bacteria; Actinomycetota; Actinomycetes; Pseudonocardiales;
            Pseudonocardiaceae; Crossiella.
REFERENCE   1  (bases 1 to 405922)
  AUTHORS   Gonzalez-Pimentel,J.L.
  TITLE     From North to South: A Spanish map of bacteria producing bioactive
            compounds in show caves
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 405922)
  AUTHORS   Gonzalez-Pimentel,J.L.
  TITLE     Direct Submission
  JOURNAL   Submitted (18-APR-2022) Agroquimica, Microbiologia Ambiental y
            Conservacion de Suelos, Instituto de Recursos Naturales y
            Agrobiologia, Av. Reina Mercedes 10, Sevilla 41012, Spain
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: 2021
            Assembly Method                   :: SPAdes v. 3.14.1
            Genome Representation             :: Full
            Expected Final Version            :: No
            Genome Coverage                   :: 200x
            Sequencing Technology             :: Illumina NovaSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_023094165.1-RS_2024_09_13
            Annotation Date                   :: 09/13/2024 06:26:08
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.8
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 9,481
            CDSs (total)                      :: 9,422
            Genes (coding)                    :: 9,365
            CDSs (with protein)               :: 9,365
            Genes (RNA)                       :: 59
            rRNAs                             :: 2, 1 (5S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 1 (5S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 57
            CDSs (without protein)            :: 57
            Pseudo Genes (ambiguous residues) :: 0 of 57
            Pseudo Genes (frameshifted)       :: 8 of 57
            Pseudo Genes (incomplete)         :: 50 of 57
            Pseudo Genes (internal stop)      :: 4 of 57
            Pseudo Genes (multiple problems)  :: 4 of 57
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 12:32:50
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 308282
            Orig. end                         :: 330858
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            JALMDK010000009.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..22576
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="lassopeptide"
                     /region_number="1"
                     /rules="(PF13471 and Asn_synthase or micJ25 or mcjC)"
                     /tool="antismash"
     cand_cluster    1..22576
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PF13471 and Asn_synthase or micJ25 or
                     mcjC)"
                     /kind="single"
                     /product="lassopeptide"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..22576
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:12576](-)"
                     /cutoff="10000"
                     /detection_rule="(PF13471 and Asn_synthase or micJ25 or
                     mcjC)"
                     /neighbourhood="10000"
                     /product="lassopeptide"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..12576)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="(PF13471 and Asn_synthase or micJ25 or
                     mcjC)"
                     /neighbourhood="10000"
                     /product="lassopeptide"
                     /protocluster_number="1"
     gene            153..1376
                     /gene="dxr"
                     /locus_tag="MZC64_RS32135"
                     /old_locus_tag="MZC64_32150"
     CDS             153..1376
                     /EC_number="1.1.1.267"
                     /GO_component="GO:0005737 - cytoplasm [Evidence IEA]"
                     /GO_function="GO:0030604 - 1-deoxy-D-xylulose-5-phosphate
                     reductoisomerase activity [Evidence IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /GO_process="GO:0008299 - isoprenoid biosynthetic process
                     [Evidence IEA]"
                     /GO_process="GO:0019288 - isopentenyl diphosphate
                     biosynthetic process, methylerythritol 4-phosphate pathway
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="dxr"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010306071.1"
                     /locus_tag="MZC64_RS32135"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MZC64_32150"
                     /product="1-deoxy-D-xylulose-5-phosphate reductoisomerase"
                     /protein_id="WP_247760500.1"
                     /transl_table=11
                     /translation="MPTSESQRSVILLGSTGSIGTQTLDVIRRHPDRFRVAGLAAGGSD
                     AATVAAQALEFEVPVVALARATAVEDLQLALYAEAQQRGFERGELRLPRILAGPGSMVE
                     LIKGNPADVVLNAMPGSQGLAPTLAALESGAVLALANKESLVAGGPLVTKLAKPGQIVP
                     VDSEHSALAQCLRGGRASEVAKLVLTASGGPFRGRTREQMAQVTLEQAMAHPNWSMGPV
                     ITINSATMINKGLELIEAQLLYGVPYDQIDVVVHPQSIVHSMVTFSDGSTLAQASPPDM
                     RLPIALSLAWPDRLTDVAPACDFSLAQSWTFEPVDDSAFPAVALARAAGTAGGCMPALY
                     NAANEEAVAAFRAGGLGFLDIVDTVARVVDEGNQWSAEPSTVDEVLAAEEWARTRAKEL
                     LGVPATAE"
     gene            1398..2681
                     /locus_tag="MZC64_RS32140"
                     /old_locus_tag="MZC64_32155"
     CDS             1398..2681
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_M50"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009943691.1"
                     /locus_tag="MZC64_RS32140"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MZC64_32155"
                     /product="RIP metalloprotease"
                     /protein_id="WP_247760499.1"
                     /sec_met_domain="Peptidase_M50 (E-value: 2.7e-49, bitscore:
                     162.2, seeds: 56, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MMFVLGVLILVFGILFSIAWHELGHLSTAKLFGVKVTQYMVGFGR
                     TLWSKKVGETEYGIKALPFGGYIRMIGMLPPVGGGKLGRSRSTGMFSSMVDDARSASAE
                     EVRPEDGDRQFYQRKPWKRIIVMFAGPFMNLILAAVLFSIALMGFGKLLPTTTVASVSK
                     CVLPASQQNAKECPADAPAAPAGAAGFQPGDKILSFNGKPAESWDAVRLEIRAAGGKTI
                     PVVVERGGQQLTLNPKLIATEMPDLDDEKKNVTVGFLGLSPTAEVQTMGVTGVVHEIGG
                     LLGKAAAAIVQLPQRVPALVSAVFGGERDRNSPVGIVGVARIGGEIAAADIPANLRISA
                     MINILAALNLSLFLFNMLPMLPLDGGHIAGALYESVRRGFAKLRRRPDPGPFDVAKLMP
                     LAYAVSLVIIAYGALVLVADIINPVRLG"
     misc_feature    2870..2886
                     /note="TFBS match to ZuR_variant_2, Zinc-responsive
                     repressor, confidence: weak, score: 19.52"
                     /tool="antismash"
     misc_feature    2942..2955
                     /note="TFBS match to BldD, Development and antibiotic
                     global regulator, confidence: weak, score: 18.63"
                     /tool="antismash"
     gene            3079..4239
                     /gene="ispG"
                     /gene_synonym="gcpE"
                     /locus_tag="MZC64_RS32145"
                     /old_locus_tag="MZC64_32160"
     CDS             3079..4239
                     /EC_number="1.17.7.1"
                     /GO_function="GO:0046429 - 4-hydroxy-3-methylbut-2-en-1-yl
                     diphosphate synthase activity (ferredoxin) [Evidence IEA]"
                     /GO_process="GO:0044237 - cellular metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="ispG"
                     /gene_synonym="gcpE"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006237349.1"
                     /locus_tag="MZC64_RS32145"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MZC64_32160"
                     /product="flavodoxin-dependent
                     (E)-4-hydroxy-3-methylbut-2-enyl-diphosphate synthase"
                     /protein_id="WP_247760498.1"
                     /transl_table=11
                     /translation="MTVDGVMLGIPAMPPPVLTERRKTRQLQVGKVGVGSDHPVSIQSM
                     TTTLTSDVNSTLQQIAELTASGCDIVRVACPSQDDADALPAIAKKSGIPVIADIHFQPK
                     YVFAAIDAGCAAVRVNPGNIKKFDDKVGDIAKAAKDAGIPIRIGVNAGSLDPRLLAKYG
                     KATPEALVESALWEASLFAEHDYHDIKISVKHNDPVVMVRAYELLAEQCDYPLHLGVTE
                     AGPTFQGTIKSAVAFGALLSRGIGDTIRVSLSAPPVEEIKVGTQILQSLNLRPRKLEIV
                     SCPSCGRAQVDVYTLAEQVTAGLEGMEVPLRVAVMGCVVNGPGEAREADLGVASGNGKG
                     QIFVKGKVIKTVPESQIVETLIEEAMRIAEDMEPVEGAAPVVTAAG"
     gene            4361..5197
                     /locus_tag="MZC64_RS32150"
                     /old_locus_tag="MZC64_32165"
     CDS             4361..5197
                     /GO_function="GO:0016747 - acyltransferase activity,
                     transferring groups other than amino-acyl groups [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007032841.1"
                     /locus_tag="MZC64_RS32150"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MZC64_32165"
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="WP_247760497.1"
                     /transl_table=11
                     /translation="MLKLAGARLLEERDLRAVRAALDADPVAACMVASRVEIAGCDPWR
                     LGGELWGFGGRLDGLCFSGANLVPLAGDLPAIKAFADRALRRRRGCSSLVGPAEQVMPL
                     WEELNPEWGPAREVREDQPLMAMAGAPVIAPDPLVRPVRPDELDRYLPAAVAMFIEEVG
                     IDPRADDGGVSYRARVAELVAGGRAFARFEDGEVVFKAEIGAMSARVGQIQGVWVHPDK
                     RGRGLGTTGTAAVADRLVRGLGRIASLYVNAYNAPARAAYQRIGFNQVGQFSTILF"
     misc_feature    4580..4582
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     misc_feature    complement(5215..5229)
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence: weak,
                     score: 16.53"
                     /tool="antismash"
     gene            5510..6685
                     /locus_tag="MZC64_RS32155"
                     /old_locus_tag="MZC64_32170"
     CDS             5510..6685
                     /GO_function="GO:0000155 - phosphorelay sensor kinase
                     activity [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1048: sensor
                     histidine kinase"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: protein motif:HMM:NF019350.5"
                     /locus_tag="MZC64_RS32155"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MZC64_32170"
                     /product="sensor histidine kinase"
                     /protein_id="WP_247760891.1"
                     /transl_table=11
                     /translation="MIRSVLRWALALQPQVADSIVAAAVTGVALLLVHRDPPFGVGPLT
                     EVTVGLVVLSVMPNAFRRLAPVPVLLLTSAGFSVYVVCGYPDVISPFGVWLALYTVAVH
                     RPARLSVPVILTVIPLMVVVLALARDSWVTLLQGMLHASVAWLLGASRHSLTQRNRQLA
                     ELAVEMHADRERQAQRAVTEERVRIARELHDVVAHHMSVISVQAGLARYVFDTDPATAS
                     TALGTIADTSREALDEMRRVLAVLRLPADDDAPEPEFDPQPGLDQIETLLERVRAAGVS
                     AELVVTGLRRSLPPGPDLCAYRVVQESLTNVIKHALPASATVHLEYRPRELTVRIADDG
                     DGAAAVASGSPGHGLAGMRERARLYEGSLSAGVRAHGGFEVELRLPLTPLE"
     gene            6703..7386
                     /locus_tag="MZC64_RS32160"
                     /old_locus_tag="MZC64_32175"
     CDS             6703..7386
                     /GO_process="GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1016: LuxR family
                     DNA-binding response regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018680400.1"
                     /locus_tag="MZC64_RS32160"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MZC64_32175"
                     /product="response regulator"
                     /protein_id="WP_374205810.1"
                     /transl_table=11
                     /translation="MRCAVTTTVLVVDDQVLVRAGFVALITAAPGLEVVGEAANGQEAI
                     ELTAAATPDVVLMDLRMPGMSGAAATGRILAEQSGPKPKVLVLTTFDLDEYVYAALRAG
                     ASGFLLKDTPPERLLAAIHTIAGGDMLFSPNITRKLVESYAHRGAQSWEPIPELSPLTS
                     REVEVLRLVGRGLTNGGIAEELAVSEATVKTHLNRAMAKLNLSSRAQAVVVAYETGLVT
                     PGQRR"
     gene            7436..9247
                     /locus_tag="MZC64_RS32165"
                     /old_locus_tag="MZC64_32180"
     CDS             7436..9247
                     /GO_function="GO:0008658 - penicillin binding [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009943695.1"
                     /locus_tag="MZC64_RS32165"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MZC64_32180"
                     /product="penicillin-binding transpeptidase
                     domain-containing protein"
                     /protein_id="WP_247760495.1"
                     /transl_table=11
                     /translation="MSAHRVVSVTASLLLVLPVAGCGLFGAEPKPEDSAKTFLSAFAGG
                     DTTTAANSTDEPKPAKELLDRVRAALKPTAVSTTVQQTLVAADDSTTASATYDVKWDLG
                     AGRTWAYQGKLELRRTEKTWRVHWAPNVIHPKLQPQQTLALREQQPQLAPILDRDGGAL
                     LNPEKVVAVLLDRKAAGDLPKAAGALAAAVSRFDKSITQQSVTDGANKVPEGQAYTVVS
                     LRDADYQQVKGAIYDLPGVRFSSQSRLLPPAGKEFASQVLPGVRKTVEDQVAGTAGWRV
                     VTLNAGGTEVEALQEQQAQPAKAVTLTLSRGVQAAAEDALEPIKNQAMLVAFQPSTGDV
                     LAVAQNAEADKGGSLALTGNYPPGSTFKVVTAAAALQAGAATPDTVLPCPGTWTLQGRK
                     IPNNDEFDLGNVPLHQAFAASCNTTFAELASKLPADSLTNAAKQFGVGVDFDLAGVRTL
                     TGKVPPAEPVVERAEDGFGQGKVVTTPFGMALVAATAARGAMPTPNLLRGTETKVVGGL
                     PAPPPAIADQLRPMMREVVLSGTAKKLNRLGEVHGKTGTAQFGDGTHSHGWFIGFRGDL
                     AFAVLVVDAGASGPAVDAAARFLGAVR"
     gene            complement(10001..10747)
                     /locus_tag="MZC64_RS32170"
                     /old_locus_tag="MZC64_32185"
     CDS             complement(10001..10747)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lassopeptide: PF13471"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF033537.1"
                     /locus_tag="MZC64_RS32170"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MZC64_32185"
                     /product="lasso peptide biosynthesis B2 protein"
                     /protein_id="WP_247760494.1"
                     /sec_met_domain="PF13471 (E-value: 1.1e-18, bitscore: 61.9,
                     seeds: 84, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTRSGATHLCVPRHIRITSSASGATFALNLRSGHWYVLNHLATTL
                     WQEILRTGDSDRAADTLANQHPRLTPEEFRRNARLLFTDLTEQGLLSLRSGVPTAEHLP
                     MIAQSKPLGSMAAAAARPSRWMLFLAHIGLLAAFCLLRLPFHLTFRIVGALTSRWCARA
                     TSQSEALVTVAAVEAAADRYPGRAACLERSLGCVITAALSRQGLRWVIGVAEDPCRFHA
                     WVETDGIAVTRSPAPHIDTFTRVLST"
     gene            complement(10744..12576)
                     /locus_tag="MZC64_RS32175"
                     /old_locus_tag="MZC64_32190"
     CDS             complement(10744..12576)
                     /GO_function="GO:0004066 - asparagine synthase
                     (glutamine-hydrolyzing) activity [Evidence IEA]"
                     /GO_process="GO:0006529 - asparagine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lassopeptide: Asn_synthase"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1177: asparagine synthase (glutamine-hydrolyzing)"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF012936.5"
                     /locus_tag="MZC64_RS32175"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MZC64_32190"
                     /product="asparagine synthase-related protein"
                     /protein_id="WP_247760493.1"
                     /sec_met_domain="Asn_synthase (E-value: 4.1e-24, bitscore:
                     80.4, seeds: 78, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MASMSMGGHAPCVLGSFPAAPGSVTGTAPIGATPVWPGLSAAVTW
                     GSWRPREFLALTCPEARLLLIGHCTADDARLRADLDTAVRRDRLELLTRWPGSFLAIVL
                     TAEKLVAFVDLAGQYPLYYHPGERLVFGTSPLPTAVASGVKLKADPLVTSAEIFCGAVP
                     MLTHGATPVHGLHRLEAGEALQVTAAGAVSRWTYADLSPDRRLAPRAGAVALRESLEIA
                     VSSRTAIEQVSTDFSGGLDSTSIAFLAARHLSAPLTAFVYHYPDAPADDLCHAVRNAGL
                     NSTIRLEIVPGTSASLPYRNLGAPPPTGLPDFAAATHERNHLRLRAVAATGGRVHLGGE
                     GADALVVAPPSYLGDLASAGRLRQLLADSGAWARLRNESPARVLSRAIRLSRTPMHRAL
                     RGYARRLGRSDAHHPSWVDAISWWPPPGLESSWLTTGARRALVEFVHDHADHAVQVVQN
                     GGVADFTARHDLRRSGAVQQQLSEMARPYEVWPQAPFLDNDVIRACTALPAYRRATGTV
                     FKPLIRAAMRDVVPSAALDRGSKGNYLGEDYRGVRAEAAGLRKRLAESPLADMGLIEPG
                     SIVQSIDRAVMGIGTPFPALNRLIAYDLWLRSLM"
     misc_feature    complement(11932..11934)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     misc_feature    complement(12561..12575)
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: weak, score: 17.49"
                     /tool="antismash"
     misc_feature    12766..12780
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: weak, score: 17.37"
                     /tool="antismash"
     misc_feature    complement(12879..12895)
                     /note="TFBS match to GnfM, Regulator of nitrogen-fixation
                     genes, confidence: weak, score: 20.23"
                     /tool="antismash"
     gene            complement(12969..14168)
                     /locus_tag="MZC64_RS32180"
                     /old_locus_tag="MZC64_32195"
     CDS             complement(12969..14168)
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1108: ROK family
                     protein"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015102841.1"
                     /locus_tag="MZC64_RS32180"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MZC64_32195"
                     /product="ROK family transcriptional regulator"
                     /protein_id="WP_247760492.1"
                     /transl_table=11
                     /translation="MGDARAILDLPSQGSDSKLKKMIIEIMVKPDRQADLARRTDLSAA
                     SVSAAIKELTNKGLVETEKGSGSSGKSRGGKVQLRQLRGVVVGVDLGFNHISVVARPVT
                     SSFDQVVQRRETPGMNRGLRLLLPDVLNLIQDAVEETGQKMTDVVTTGLAVPRMVDPLT
                     GTFTPPVLAPWRAEDRPAQELSAKLGVPVAMDNDANLGALAEQTYGSDEAIEHVAYVKA
                     STGVGVGIMIGSILLRGQRGMAGELGHLTIEPDGEMCLCGGRGCLDTIVGAESLVAKAK
                     QAQRGSSRDIPSTLSALVHNAQNGDAVCGRILNDAGRVLGFALAQLCNLINPRHIILGG
                     ELAEAGHLVLDTCRQELTRYALTGTVHQDGDFELRTSALSPFAEAQGALILGLQSRSSK
                     "
     misc_feature    complement(14200..14214)
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: weak, score: 17.44"
                     /tool="antismash"
     gene            14461..15318
                     /gene="map"
                     /locus_tag="MZC64_RS32185"
                     /old_locus_tag="MZC64_32200"
     CDS             14461..15318
                     /EC_number="3.4.11.18"
                     /GO_function="GO:0070006 - metalloaminopeptidase activity
                     [Evidence IEA]"
                     /GO_process="GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /gene="map"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1172: methionine aminopeptidase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009074619.1"
                     /locus_tag="MZC64_RS32185"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MZC64_32200"
                     /product="type I methionyl aminopeptidase"
                     /protein_id="WP_247760491.1"
                     /transl_table=11
                     /translation="MPVRAPLKPGQLSPRRPVPAHIDRPEYVDKPAPQRNTDPWVQPPE
                     IIEAMRVAGRLAAQALAEAGKVCVPGATTDEVDAVVHEFLCDNGAYPSTLGYRNYPKSC
                     CTSLNEVICHGIPDTTVIEDGDIVNVDVTAFIGGVHGDTNGTFLAGNVAEEAQLLVERT
                     REATHRAIKAVKPGRQINVIGRVIEAYANRFGYGVVRDFTGHGIGRSFHSGLVVLHYDE
                     PSMDTVLEPGMTFTIEPMITLGTIDYDMWADGWTVTTKDKKFTAQFEHTVLVTTDGVEI
                     LTLP"
     gene            15315..16853
                     /locus_tag="MZC64_RS32190"
                     /old_locus_tag="MZC64_32205"
     CDS             15315..16853
                     /GO_function="GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /GO_process="GO:0009236 - cobalamin biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015104401.1"
                     /locus_tag="MZC64_RS32190"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MZC64_32205"
                     /product="cobyric acid synthase"
                     /protein_id="WP_247760490.1"
                     /transl_table=11
                     /translation="MTGGGLLIAGTTSDAGKSVLVAGLCRWLARRGVRVAPFKAQNMSN
                     NSVVTADGGEIGRAQAVQAAAAGLAPSVRFNPVLLKPGSDRSSQVVLLGKVIGEVTALS
                     YRERKTHLAATVLATLDGLRAEYEAVICEGAGSPTEINLRANDIANMGLARAANLPVLV
                     VGDIDRGGVFAHLFGTLALLDPADQALVSGFVINKFRGDPALLDPGLRQLTALTGRPVH
                     GVLPWREELWLDAEDSLSYAADGVVGRPAAPVGEQWLRVAVPRLPRISNATDVEALAGE
                     PGVSVRFVTEPSRLADADLVVLPGSKSTVADLDWLRRTGLAAAITRHAAAGLPVTGICG
                     GYQMLAATLHDPVESRAGTVDGLGLLDLDIEFHPDKTLANPAGAALGHPVRGYEIHHGR
                     PARRAEHLAPLITLPDGTGEGALHGPIAGTHWHGLFENDGFRRDFLTWAATRAGRTGFT
                     PAPDTDFAAARAAQLDLLGDLVADHLDTDAVQRLLESGAPRGLPAIPPGAPPSC"
     gene            16996..17475
                     /locus_tag="MZC64_RS32195"
                     /old_locus_tag="MZC64_32210"
     CDS             16996..17475
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF039955.4"
                     /locus_tag="MZC64_RS32195"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MZC64_32210"
                     /product="DUF5994 family protein"
                     /protein_id="WP_247760489.1"
                     /transl_table=11
                     /translation="MTDMTSGSTQRQDFQPPAAGAVQHEPRVQVKPVDASPGFLDGGWW
                     PNSMDLGRALPALLSALRERLGPVSRVTYHLEHWLPAPRRLTVGGRVVRLEGYRSPDPR
                     TITVTGQSGQRLVLLVVPPETTESEARRVLDLTAGADNRDSAASLLGVISPAEQD"
     gene            complement(17503..18300)
                     /locus_tag="MZC64_RS32200"
                     /old_locus_tag="MZC64_32215"
     CDS             complement(17503..18300)
                     /EC_number="3.1.-.-"
                     /GO_component="GO:0005829 - cytosol [Evidence IEA]"
                     /GO_function="GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF013866.5"
                     /locus_tag="MZC64_RS32200"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MZC64_32215"
                     /product="dienelactone hydrolase family protein"
                     /protein_id="WP_247760488.1"
                     /transl_table=11
                     /translation="MTAGAPETDLTGWRRAPFTAAGSTYDCFEKGSGPGVVVLPEIPGM
                     TPSVLGFADHLVDNGFTVLIVSAFGTPGAPESTRTGLPVAAKACVSAEFRAFATNAKRP
                     FSDYLRAVARDLNERTPGPGVGVIGMCFTGGFALAAAVDEVVLAPVGSQPSLPLPLGAR
                     RKADPGMSEAELSRIAARTVESGLCLMGLRFSADRLVPGERFRTLTDRLGEAFRVVELD
                     SRPGNADGFKSNAHSVLTREVREGNAAMAARDQVVAFLHERLG"
     misc_feature    18352..18367
                     /note="TFBS match to CopR, Copper-responsive regulator,
                     confidence: weak, score: 17.49"
                     /tool="antismash"
     misc_feature    complement(18515..18525)
                     /note="TFBS match to HypR, L-hydroxyproline utilization
                     repressor, confidence: weak, score: 18.94"
                     /tool="antismash"
     misc_feature    complement(19292..19305)
                     /note="TFBS match to ANR, Anaerobic transcriptional
                     regulator, confidence: weak, score: 19.57"
                     /tool="antismash"
     misc_feature    19446..19460
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: weak, score: 18.26"
                     /tool="antismash"
     misc_feature    20630..20643
                     /note="TFBS match to ANR, Anaerobic transcriptional
                     regulator, confidence: weak, score: 18.47"
                     /tool="antismash"
     misc_feature    complement(21228..21242)
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: weak, score: 17.8"
                     /tool="antismash"
     misc_feature    complement(21939..21954)
                     /note="TFBS match to RutR, Regulator of the pyrimidine and
                     purine metabolism, confidence: weak, score: 19.79"
                     /tool="antismash"
     misc_feature    complement(22128..22142)
                     /note="TFBS match to VqsM, Regulator of quorum-sensing
                     signalling systems, confidence: medium, score: 17.8"
                     /tool="antismash"
     misc_feature    complement(22181..22198)
                     /note="TFBS match to HipB, Bacterial antitoxin HipB,
                     confidence: weak, score: 19.59"
                     /tool="antismash"
ORIGIN
        1 tgcgcactga cagagttacc cggcgcttcg gcgttcacac cctgttgctg atcactcgtc
       61 tgagcgccga tgcccgagga tggctgcatg gtcctgccgc gtgcggcggg ccgcattccg
      121 gatcagggag aatgaccgtg atggagtacc gaatgcccac ttccgagtca cagcgttccg
      181 tcattctgct cggctcgacc gggtcgatcg gcacccagac gctggatgtc atccgtcggc
      241 acccggaccg cttccgggtg gccgggctcg ccgcgggcgg cagcgacgcc gccacggtgg
      301 ccgcgcaggc gctggagttc gaggtgcccg tggtcgcgct ggcgcgggcg actgccgtgg
      361 aggacctgca gctcgcgctg tacgccgagg cgcagcagcg cgggttcgag cgcggtgagc
      421 tgcggctgcc gcggatcctg gccgggccgg gctcgatggt cgagctgatc aagggcaacc
      481 cggcggacgt ggtgctcaac gcgatgcccg gctcgcaggg cctggccccg acgctggccg
      541 cgctggaaag cggcgcggtg ctcgcgctgg ccaacaagga atcgctggtc gcgggcggtc
      601 cgctggtcac caagctggcc aagccgggcc agatcgtgcc ggtggactcc gagcactccg
      661 cgctcgccca gtgcctgcgc ggcggacgcg ccagcgaggt cgccaagctg gtgctgaccg
      721 cctccggtgg ccccttccgc ggtcgcacca gggagcagat ggcccaggtc acgctggaac
      781 aggcgatggc gcacccgaac tggtcgatgg gcccagtgat caccatcaac tcggccacca
      841 tgatcaacaa ggggctggag ctgatcgagg cccagctgct ctacggcgtg ccgtacgacc
      901 agatcgacgt cgtcgtgcac ccgcagtcca tcgtgcactc gatggtcacc ttcagcgacg
      961 gctccaccct ggcccaggcc agcccgccgg acatgcggct gcccatcgcg ctgtccctgg
     1021 cctggccgga ccggctcacc gacgtggccc cagcctgtga cttcagcctc gcccagtcct
     1081 ggaccttcga gccggtggac gactccgcgt tccccgcggt ggcgctggcc agggccgcgg
     1141 gcacggccgg tggctgcatg cccgcgctgt acaacgcggc caacgaggag gcggtcgccg
     1201 ccttccgtgc cggtggcctc ggtttcctgg acattgtgga cacggtcgcc cgggttgtgg
     1261 atgagggcaa ccagtggtcc gccgaaccgt ctaccgttga cgaggtgctg gcagcggagg
     1321 agtgggcccg gacccgggcc aaggaactcc tcggcgtgcc cgccacggcc gagtaagcag
     1381 aacgaggagc cacctagatg atgttcgtgc tgggcgtcct gatcctggtg ttcgggatcc
     1441 tgttctccat cgcctggcac gagctgggcc acctcagcac ggccaagctg ttcggcgtca
     1501 aggtcaccca gtacatggtg ggcttcgggc gcacgctgtg gtcgaagaag gtcggcgaga
     1561 ccgagtacgg catcaaggcg ctgcccttcg gcggctacat ccggatgatc gggatgttgc
     1621 cgccggtggg cggcggcaag ctgggccgca gccgcagcac cggcatgttc tcctcgatgg
     1681 tcgacgacgc gcgcagcgcc tcggccgagg aggtccgccc ggaagacggt gaccgccagt
     1741 tctaccagcg gaaaccgtgg aagcggatca tcgtcatgtt cgccggaccg ttcatgaacc
     1801 tgatcctggc cgcggtgctg ttctccatcg cgctgatggg cttcggcaag ctgctgccga
     1861 ccaccacggt ggccagtgtg agcaagtgcg tgctgccggc cagccagcag aacgccaagg
     1921 aatgcccggc cgacgccccg gccgccccgg cgggtgcggc cggtttccag cccggcgaca
     1981 agatcctcag cttcaacggc aagcccgcgg agagctggga cgcggtccgg ctggagatcc
     2041 gggcggcggg cggcaagacg attccggtgg tggtcgagcg cggcgggcag cagctcacgc
     2101 tgaacccgaa gctgatcgcc accgagatgc cggacctgga cgacgagaag aagaacgtca
     2161 ccgtcggctt cctgggactc tcgcccaccg ccgaggtgca gaccatgggc gtcaccggcg
     2221 tggtgcacga gatcggcggc ctgctcggca aggcggccgc cgccatcgtg cagctgccgc
     2281 agcgggtccc ggccctggtc agcgcggtct tcggcggtga acgggaccgc aactccccgg
     2341 tcggcatcgt cggtgtggcc cgcatcggcg gcgagatcgc ggccgccgac atcccggcca
     2401 acctgcggat cagcgccatg atcaacatcc tggccgcgct gaacctgtcc ctgttcctgt
     2461 tcaacatgct gccgatgctc ccgctggacg gcggccacat cgccggcgcg ctgtacgagt
     2521 ccgtccgccg cggcttcgcc aaactccgcc gccgccccga cccgggcccc ttcgacgtcg
     2581 ccaagctgat gccgctggcc tacgccgtct cgctggtgat catcgcctac ggcgccctgg
     2641 tcctggtcgc cgacatcatc aaccccgtcc gcctcggctg acccgtcgac ttggcccaac
     2701 tcgtacgccc ggttgggcca agtgggcgta ccgcttggcc caactcggcg gggcgccgag
     2761 cctgacctgc gccggatcgc tcgctgacct gccgcgcacg tgacgctcgc ccctgccccg
     2821 cgaagatcat ggttcggcca agtacccttg cggtgaagtc aaccggcagt tgtgatcaca
     2881 tcccatacag cctttcggga aagacagaat cgatccaact cacagtttgg gcggcagact
     2941 tgtgactctg cgtagatgca tgcgcggtga atctcgttac acttccgtcc gtggggtggt
     3001 ctacctgacc ccaagggaga acttccctgt cgcgtaaagt agtcaatacc ggccgaccct
     3061 atggggagtt gaacaaagat gaccgttgac ggtgtcatgc tcggcattcc ggcgatgcct
     3121 ccgcctgtgc tgaccgagcg ccgcaagacc cgtcagctcc aggtgggcaa ggtgggtgtg
     3181 ggttccgacc accccgtgtc catccaatcc atgaccacca cgctgacctc tgacgtcaac
     3241 tcgaccctgc agcagatcgc cgaactgacc gcttcgggct gcgacatcgt gcgggtcgcc
     3301 tgcccgtccc aggacgacgc ggacgcgctc ccggcgatcg cgaagaagtc cggtattccg
     3361 gtgatcgcgg atatccattt ccagccgaag tacgtattcg ccgccattga cgccggctgc
     3421 gccgcggtcc gggtcaatcc gggcaacatc aagaagttcg acgacaaggt cggggacatc
     3481 gccaaggcgg caaaggacgc gggcatcccg atccggatcg gcgtcaacgc cgggtcgctg
     3541 gacccgcgcc tgctggccaa gtacggcaag gccacgccgg aggcgctggt ggagtcggcc
     3601 ctctgggagg cctcgctctt cgccgaacac gactaccacg acatcaagat ctcggtgaag
     3661 cacaacgacc cggtcgtcat ggtccgggcc tacgagctgc tggccgagca gtgcgactac
     3721 ccgctgcacc tgggcgtcac cgaggcgggc ccgactttcc agggcaccat caagtccgcg
     3781 gtggccttcg gcgcgctgct ctcccgcggc atcggcgaca ccatccgggt ctcgctctcc
     3841 gccccgccgg tggaggagat caaggtcggc acccagatcc tgcagtcgct caacctgcgc
     3901 ccgcgcaagc tggagatcgt ctcctgcccc tcctgcggcc gcgcccaggt cgacgtctac
     3961 accctggccg agcaggtcac cgccggtctg gagggcatgg aggtgccgct gcgggtggcg
     4021 gtcatgggct gtgtcgtgaa cggccccggt gaggcccgcg aggccgacct gggggtcgcc
     4081 tccggcaacg gcaagggcca gatcttcgtc aagggcaagg tcatcaagac cgtgccggag
     4141 tcgcagatcg tggagaccct gatcgaagag gccatgcgga tcgccgagga catggagccc
     4201 gtcgagggcg ccgctcccgt ggtgaccgcc gcgggctgac ccaaggtcaa ccgccaatcg
     4261 gcgagtccgt catcccccgg tgaactttct gtgaaccggg ggatgacgac cattgggtga
     4321 tggtgtgccc tccgccggtt gtgtttggca gacttgcggg gtgctgaagc ttgccggggc
     4381 tcggctgctc gaggaacgcg atctgcgagc ggtacgggct gccctcgacg ccgaccccgt
     4441 ggcagcgtgc atggtcgcct cccgggtgga gatcgccggt tgtgatccct ggcggctggg
     4501 cggtgaactc tggggcttcg gcggcaggct ggacggtctc tgcttctccg gcgccaacct
     4561 ggtgccgctg gccggtgact tacccgcgat caaggcattc gccgaccgcg cgctgcgccg
     4621 tcgccgcggc tgctcctcac tggtcggacc ggccgagcag gtcatgccgc tgtgggaaga
     4681 gctgaacccg gagtggggcc cggcccgcga ggtgcgcgag gaccagccgc tgatggccat
     4741 ggcaggcgcc ccggtgatcg cgcccgaccc gctggtgcgc ccggtccggc cggatgagct
     4801 ggaccgctac ctgcccgccg cggtggccat gttcatcgaa gaggtcggca tcgaccccag
     4861 ggccgacgac ggtggcgtga gctaccgggc cagggtcgcc gaactggtcg cgggcgggcg
     4921 cgcgttcgcc cggttcgagg acggcgaggt cgtgttcaag gccgagatcg gcgccatgtc
     4981 cgcgcgggtc ggccagatcc agggtgtctg ggtgcacccg gacaagcggg gcaggggact
     5041 gggcaccacc ggcaccgccg cggtggccga ccggctggtc cgcggcctcg gccggatcgc
     5101 cagcctctac gtcaacgcct acaacgcccc ggcccgcgcg gcctaccagc ggatcggctt
     5161 caaccaggtc gggcagttca gcacgatcct gttctgaaca gttgtaatga cacaactgtg
     5221 ctgaaaaaag aaggcaatcg tcccggccgg gctccgagtc ggggcccatc cgtactcgac
     5281 ccggccggga cgactacccg agctggtggt cccaccaacc cccaggcggc aggaacaccg
     5341 gcaatcaagc tatgccctgt gcggagcgtg gtcgtcgcac tcccaaccga cttttcccac
     5401 caactcgggt ggtagcccgg cccggttctg caacttttgc ggtatgccgg atgccatgcg
     5461 caagtacggc gcgacacgct ccggcgcgca ctaccgttgg tccgtgcgca tgatcagatc
     5521 ggtactgcgc tgggccctgg cgctccagcc gcaggtcgcc gactcgatcg tggccgccgc
     5581 cgtcaccggt gtcgccctgc tgttggtcca tcgggacccc ccgttcggcg taggtccgct
     5641 gaccgaggtc accgtcggac tggtcgtgct gtcggtgatg cccaacgcct tccgcaggct
     5701 cgccccggtc ccggtgctgc tgctgaccag cgccggtttc tcggtctacg tggtctgcgg
     5761 gtaccccgat gtgatcagtc cgttcggggt gtggctggcc ctctacacgg tggccgtgca
     5821 ccgcccggcc cggttgtccg tgccggtgat cctgaccgtg atcccgctga tggtggtggt
     5881 gctcgcgctg gccagggact cctgggtcac cctgttgcag gggatgttgc acgccagcgt
     5941 ggcctggttg ctcggcgcga gcaggcacag cctgacccag cgcaaccggc agctggccga
     6001 gctggccgtg gagatgcacg ccgaccggga gcggcaggcc cagcgcgcgg tcaccgagga
     6061 acgggtgcgc atcgcccgcg aactgcacga cgtggtcgcg caccacatgt cggtgatctc
     6121 ggtgcaggcc gggctggccc gctacgtctt cgacaccgac ccggccaccg cgagcaccgc
     6181 gctgggcacc atcgccgaca ccagccggga ggccctggac gagatgcgcc gggtactggc
     6241 cgtgctgcgg ttgcccgccg acgacgacgc gccggaaccg gagttcgacc cgcagcccgg
     6301 cctggaccag atcgagaccc tgctggagcg ggtgcgtgcc gccggggtgt cggccgaact
     6361 ggtggtcacc ggcctgcgcc gctcgctgcc gcccggcccg gacctgtgcg cctaccgggt
     6421 ggtgcaggaa tcgctgacca acgtcatcaa gcacgccctg cccgcctcgg ccaccgtgca
     6481 cctggagtac cggccgcggg agctgaccgt gcggatcgcc gacgacggcg acggtgcggc
     6541 ggccgtcgcg tcggggtcgc cgggccatgg ccttgccgga atgcgggaac gggcccggct
     6601 ctacgaaggt agcctctccg ctggcgtgcg cgcgcacggc gggttcgagg tggagctgcg
     6661 actgccgctc acgccgctgg agtagccacc ggggcgactg ggatgaggtg cgcagtgacg
     6721 accaccgtcc tcgtcgtgga cgaccaggtg ctggtgcgcg ccggtttcgt cgccctgatc
     6781 accgccgccc ccggactgga ggtggtcggc gaggcggcca acggccagga ggcgatcgag
     6841 ctgaccgccg cggccacccc cgacgtggtg ctgatggacc tgcgcatgcc agggatgagc
     6901 ggggccgccg ccaccgggcg gatcctggcc gagcagtcgg ggcccaagcc gaaggtgctg
     6961 gtgctgacca ccttcgacct ggacgagtac gtctacgccg cgctgcgcgc cggggcgtcg
     7021 ggcttcctgc tcaaggacac cccgccggaa cgcctgctcg ccgccatcca caccatcgcg
     7081 ggcggggaca tgctgttctc gcccaacatc acccgcaaat tggtcgagtc ctacgcccac
     7141 cgcggcgccc agagctggga gccgatcccc gagctgtccc cgctgaccag ccgcgaggtc
     7201 gaggtgctgc gcctggtcgg gcgcgggctg accaacggcg gcatcgccga ggaactcgcg
     7261 gtcagcgagg ccaccgtgaa gacccacctc aaccgggcga tggccaagct caacctgtcc
     7321 agccgggccc aggccgtggt ggtcgcctac gagaccggat tggtcacccc aggtcagcgg
     7381 cgctgagggc gggcttcatc ctgggcagac acgggtgcgc ggcatactgg ccgccgtgtc
     7441 cgctcaccgg gtcgtcagcg tcaccgcctc gctcctcctc gtgctcccgg tcgccggttg
     7501 cggcctgttc ggcgccgaac ccaaacccga ggactcggcc aagaccttcc tgtccgcctt
     7561 cgccggtggc gacaccacca ccgccgcgaa cagcacggac gagcccaaac cggccaagga
     7621 actgctggac cgggtgcgcg ccgcgctgaa gccgaccgcg gtcagcacca ccgtgcagca
     7681 gacgctggta gccgcggacg actccaccac ggcgagtgcc acttacgacg tgaaatggga
     7741 tctcggcgcc ggtcgcacct gggcctacca gggcaaactg gagctgcgcc gcaccgagaa
     7801 gacctggcgg gtgcactggg cgcccaacgt gatccacccg aagctgcaac cgcagcagac
     7861 cctcgcgctg cgcgagcagc agccgcagct ggcgccgatc ctggaccggg acggcggcgc
     7921 gctgctcaac ccggagaagg tcgtcgcggt gctgctggac cgcaaggccg ccggtgacct
     7981 gcccaaggcc gcgggcgcgc tggccgccgc ggtgtcccgc ttcgacaagt cgatcaccca
     8041 gcagagcgtg accgacggcg cgaacaaggt gccggagggc caggcctaca ccgtggtcag
     8101 cctgcgcgac gcggactacc agcaggtcaa gggcgccatc tacgacctgc caggggtccg
     8161 cttcagcagc cagtcgcggc tgctgccccc cgcgggcaag gagttcgcct cccaggtgct
     8221 gcccggggtg cgcaagacgg tggaggacca ggtcgcgggc accgcgggct ggcgggtggt
     8281 caccctcaac gcgggcggca ccgaggtcga ggccctgcag gagcagcagg cccagccggc
     8341 caaggcggtc accctgacgc tgagccgggg cgtgcaggcc gcggccgagg acgcgctgga
     8401 gccgatcaag aaccaggcca tgctggtcgc cttccagccc tccaccggcg atgtgctcgc
     8461 ggtggcccag aacgccgagg cggacaaggg cggctcgctg gcgctgaccg gcaactaccc
     8521 gccgggctcc accttcaagg tggtcaccgc ggcggccgcg ttgcaggcgg gggcggccac
     8581 cccggacacg gtgctgccct gccccggcac ctggaccctg cagggccgca agatccccaa
     8641 caacgacgag ttcgacctgg gcaacgtgcc gctgcaccag gcattcgccg cctcctgcaa
     8701 caccaccttc gccgaactgg ccagcaaact gccggccgac tcgctgacca acgcggccaa
     8761 gcagttcggc gtcggcgtgg acttcgacct ggccggggtg cgcaccctga ccggcaaggt
     8821 cccgccggcc gagccggtgg tggagcgggc cgaggacggc ttcggccagg gcaaggtggt
     8881 caccaccccg ttcggcatgg ccctggtcgc ggccaccgcg gcccgcggcg ccatgcccac
     8941 cccgaacctg ctgcgcggca ccgagaccaa ggtggtcggc ggcctgcccg ccccgccgcc
     9001 cgcgatcgcc gaccagctcc ggccgatgat gcgcgaggtc gtcctcagcg gcaccgcgaa
     9061 gaagctgaac cggctcggcg aggtgcacgg caagaccggc accgcgcagt tcggcgacgg
     9121 cacccactcg cacggctggt tcatcggctt ccgcggtgac ctggccttcg cggtgctggt
     9181 ggtggacgcg ggcgcgtccg gcccggcggt ggacgcggcg gcccgattcc tgggcgcggt
     9241 gcgctagcca cgccaactcc gccttcggcc ggacgaacgt tcgactgttg ggccacttgg
     9301 gtgaacttgg gattctgacg gatatccatc cgattgaccc ttgcgggcgc ttctcatggc
     9361 ttctgcttct tgtgtgtgat gacgaggcgg gcattcgggt tggtgccttc gtcaaaacag
     9421 cggttccgcg gctcgctggc catgcctgac gtgtcggtgg cgtccacctg ccgaggtgca
     9481 ggtgtcgacg gtcacggtgg gcggggagca ggccgccggt ggcgcgatca atacggcttg
     9541 gtgtgcgagg actggcatgc tggggttcga gctgatcgcg gcgcgggttg aggtggcgtc
     9601 aatttccttc agtctgaaat tgggtagagc cggaaattga cgtgcggcta ctttcgtgaa
     9661 cctgtgaaat cacgtgtttc cgcgtagctg gggcgagttg accccggttg tgttgtctgt
     9721 gagcggagcg cacagtggca ccacgtcgac cagtcagcga ggagtcccgg aatgaaaaat
     9781 cgaaatgcgg cagacctgga aattcaagtg aagttctccg ccggtcgagc ctggcggaaa
     9841 tgtgttccgg ccgtgcgtcg agggctgttg cccgcggtgt gcgtcctgta cgtcctgttc
     9901 ggggacttcg gagtctcggt cgagttccta gtcaaatagg acaacagtgc gcgggtgctg
     9961 cggccagctc ctttgggggc tcggtcgcag catttttttg tcaggtcgag agaactcggg
    10021 tgaaggtgtc gatgtgcggc gccggtgagc gcgtaaccgc gatgccgtca gtttccaccc
    10081 aggcgtggaa acggcatggg tcctcggcga ccccgatgac ccagcgcagt ccttgccggg
    10141 acagtgccgc cgtgatgacg cagcccagcg accgttccag gcaggcggcc cggccggggt
    10201 accggtcagc tgccgcctcc accgccgcga ccgtcaccag ggcttctgac tgggacgtgg
    10261 cgcgtgcgca ccacctgctg gtaagggcac cgacgatccg gaaggtcagg tggaacggga
    10321 gccgcaacag gcagaacgcc gcgaggagtc cgatatgcgc taggaacagc atccaccggg
    10381 acggcctcgc cgccgcggct gccatggacc cgagcggctt gctctgggcg atcatgggca
    10441 ggtgttccgc agtgggcacg ccgctccgga gtgagaggag gccctgttcg gtcaggtcgg
    10501 tgaacaggag ccgggcattg cgccggaatt cctccggagt gaggcgcgga tgctggttcg
    10561 ccagggtatc ggcggctcga tcgctgtcac ctgtgcgcag tatttcctgc cacagtgtgg
    10621 tggccaagtg attcagcacg taccaatgcc cggacctcag gttgagtgcg aatgtcgcgc
    10681 cactggcact gctggtgatg cgtatatggc ggggaacgca gagatgcgtt gcgccggatc
    10741 gggtcacatc aagctcctga gccagaggtc gtaggcgatc agtcgattca gcgccggaaa
    10801 gggcgtgccg atccccataa ccgcccgatc gatcgattgg acgattgatc ccggctcgat
    10861 caatcccata tccgcgagcg gggactcggc gagtcgtttt cgcagtccgg cggcctcggc
    10921 tcgtacgccc cggtagtcct cgcccaggta gttgcccttg gaaccgcgat ccagcgcggc
    10981 cgagggcacc acgtcgcgca ttgctgcgcg gatcaagggc ttgaacaccg ttccggtcgc
    11041 gcgccggtac gcgggcaacg cggtgcaggc gcggatgacg tcattgtcca ggaacggcgc
    11101 ctggggccac acctcgtacg gacgggccat ttcgctcagc tgctgttgga ctgccccgga
    11161 ccgccgcagg tcgtgccgcg cggtgaagtc ggcgactcca ccgttctgca cgacctgcac
    11221 cgcgtggtcc gcgtgatcat gcacgaactc caccagcgcg cggcgcgcgc cggtggtgag
    11281 ccatgaggac tccagacctg gcggaggcca ccaggagatc gcgtccaccc agctcgggtg
    11341 gtgggcatcc gagcggccca gccggcgggc gtacccgcgt agtgctcggt gcatcggcgt
    11401 cctcgacaac cggatcgccc gggacaacac ccgagccggg gattcgttcc gcagccgggc
    11461 ccacgcgccc gaatccgcga gcaactggcg cagccgtccc gcgctggcga gatcgcccag
    11521 ataggagggt ggcgcgacca ccagcgcatc ggccccctcc ccgccgaggt gcaccctccc
    11581 gccggtggcc gccaccgccc gtaggcggag gtggtttcgt tcgtgcgtgg ccgccgcgaa
    11641 gtcaggcagt ccggtggggg gcggcgcgcc gagattccgg tacggcaggc tcgcgctcgt
    11701 tcccggcacg atttccaggc ggatcgtcga gttcaggccc gcgttgcgca ccgcgtggca
    11761 gaggtcgtca gcaggcgcgt cgggatagtg gtagacgaaa gcggtcaacg gggccgacaa
    11821 gtgccgggcc gcgagaaagg cgatcgaggt ggagtccagt ccgccactga agtcggtgct
    11881 cacctgttcg atcgcggtcc ggctcgagac ggcgatctcc agcgactcgc gtaacgccac
    11941 cgctcccgca cgcggtgcga gccgccgatc cggcgagaga tccgcatagg tccagcgcga
    12001 gaccgctccg gcggccgtca cctggagcgc ttcgcccgcc tccagccggt gcagcccatg
    12061 aaccggtgtc gcgccatgcg tgagcatcgg caccgcaccg cagaagatct ccgcgctggt
    12121 gacgagcgga tcggccttga gtttgacgcc cgaagccacc gcggtgggca acgggctcgt
    12181 gccgaagacc agccgctcgc ctgggtggta gtacaacggg tactggccgg cgagatcgac
    12241 gaacgcgacg agtttctccg cggtgagcac gatcgcgagg aagctgcccg gccaccgggt
    12301 gaggagttcc aaccgatccc tccgcacggc tgtgtccagg tcggcgcgta gccgggcgtc
    12361 gtcagcggtg cagtgcccga tgagcagcaa gcgcgcctcg gggcaggtga gtgcgaggaa
    12421 ctcacggggg cgccagctac cccaggtgac cgcggcggac agacctggcc agaccggtgt
    12481 cgcgccgatc ggggctgtcc cggtgacgct gcccggtgcc gcggggaaag agcccagaac
    12541 gcacggtgcg tggccgccca tggacatgga tgccatgaat ctgttaccag tagtattgcg
    12601 agtttgcgtc cgcgtttccg ctggacgaac tgcccagcgt tatgtgccgg acatggccga
    12661 gatcgatcac cagtggcagt tcgctgtgtt gctcggtttc gttcgtcgca gtgttcgctg
    12721 ttggccgatc cggtgttgtg tcctgtctcg cgcgagcttg ccggaagaat ctcatgatca
    12781 taccttcgat cggagcgtgc tggaattcgc tggcggcacc atgtgagcag atttgcctgg
    12841 ttgttggcaa gtccggccgg cgggtggccc cgatcgagtg gcgagctttt cggcagatct
    12901 acgatgcaat tgatgagacc gatttttcgg tatgaacggt catggtcgaa tccggtccac
    12961 cggaacgttc attttgacga tctggactgg agtccgagta tgagcgcgcc ctgagcctcg
    13021 gcgaacgggc tcaacgcgct ggtgcgcagc tcgaaatcac cgtcctggtg caccgtgccc
    13081 gtgagggcgt accgcgtcag ttcctggcgg caggtgtcca gcaccaggtg tcccgcctcc
    13141 gcgagttcgc cgccgaggat gatgtgccgc gggttgatga ggttgcacag ctgggccagc
    13201 gcgaagccga gcacccggcc ggcgtcgttg aggatgcggc cgcacacggc gtcaccgttc
    13261 tgcgcgttgt gcacgagtgc gctcagggtg gacgggatgt cccgcgagct gccccgctga
    13321 gcctgcttgg ccttagccac gagcgattcg gcgcccacga tggtgtccag acaaccgcgt
    13381 ccgccgcaca ggcacatctc gccatcgggc tcgatggtca ggtgtccgag ttcgccggcc
    13441 atgccgcgct gcccgcgcag gaggatcgag ccgatcatga tgcccacgcc gacgccggtg
    13501 gacgccttca cgtaggcgac atgctcgata gcctcgtcgg agccgtatgt ctgctcggcc
    13561 agcgcgccga gattcgcgtc gttgtccatg gccacgggca ccccgagctt cgcgctgagt
    13621 tcctgcgctg gccggtcctc cgcccgccac ggcgcgagca cgggaggggt gaacgtgccg
    13681 gtcagcggat cgaccatccg aggtacggcc aagccggtgg tcaccacgtc cgtcatcttc
    13741 tggccggtct cctcgaccgc gtcctggatg aggttcagca catcgggcag cagcaggcgc
    13801 agaccccggt tcatgccggg cgtctccctg cgctggacca cctggtcgaa cgaactggtc
    13861 accggcctgg ccaccaccga gatgtggttg aaccccagat ccaccccgac cacgacaccg
    13921 cgtagctgcc gcagctggac ttttccgcca cgcgacttgc ctgaacttcc actccctttt
    13981 tcggtctcca ccaggccctt gttggtcaac tcctttatcg ccgcggaaac agaagccgcc
    14041 gacaagtcgg ttcgccgggc gaggtctgcc tgccggtcag gcttgaccat gatttcgatg
    14101 atcatctttt tgagtttcga atcactgcct tgagagggga gatcaagtat tgcgcgtgcg
    14161 tcgcccatgg cgccgacctc tccgcaaaat tgcggttcct gaaattgatc tcgatgcccg
    14221 aaggctagca tcgaatcgtt caatctgaag agcgtcaccg ttcagatgtc tgcctgatgc
    14281 gggatcgacg tctggtggct aacggaaggc ggtcctaggg agatcggttg aattctaccc
    14341 ggatggccga atccggagag aggagattgc cgatcggccg gggttcggct gaggcgacct
    14401 ccggtcccgg accggccggt ccggtccgcg cgcgaagccc ggcgtcgtag gctggagggc
    14461 atgcccgtcc gtgccccact gaagcccggc cagctctcgc cgcggcgtcc cgtgcccgct
    14521 cacatcgatc gtcccgagta cgtggacaag ccggcgcccc agcgcaacac cgatccgtgg
    14581 gtgcagccgc cggagatcat cgaggccatg cgggtggccg ggcggctcgc ggcgcaggca
    14641 ctggccgagg cgggcaaggt gtgcgtgccg ggcgcgacca ccgacgaggt cgacgcggtg
    14701 gtgcacgagt tcctctgcga caacggggcc tacccgtcca cgctgggcta ccggaactac
    14761 ccgaagtcct gctgcacctc gctcaacgag gtcatctgcc acggcatccc ggacaccacg
    14821 gtgatcgagg acggggacat cgtcaacgtc gacgtcaccg cgttcatcgg cggcgtgcac
    14881 ggcgacacca acggcacctt cctggcaggc aacgtcgccg aagaggccca gttgctggtc
    14941 gagcggacca gggaggccac ccaccgggcg atcaaggcgg tcaagccggg ccgccagatc
    15001 aacgtgatcg gccgggtcat cgaggcctac gccaaccggt tcggctacgg cgtggtgcgc
    15061 gacttcaccg ggcacggcat cggccgctcc ttccacagcg gcctggtcgt gctgcactac
    15121 gacgagccca gcatggacac cgtgctggag ccgggcatga ccttcaccat cgagccgatg
    15181 atcaccctgg gcaccatcga ctacgacatg tgggccgacg gctggacggt gaccaccaag
    15241 gacaagaagt tcaccgcgca gttcgagcac accgtgctgg tcaccaccga cggtgtcgag
    15301 atcctgaccc tgccttgacc ggcggtggcc tgctgatcgc gggcaccacc tccgacgcgg
    15361 gcaagagcgt gctcgtcgcc gggctgtgcc gctggctggc ccggcgcggg gtgcgggtgg
    15421 cgccgttcaa ggcgcagaac atgtccaaca actcggtggt caccgccgac ggcggcgaga
    15481 tcggccgggc ccaggcggtg caggccgccg cggccgggct ggcgccctcg gtgcggttca
    15541 acccggtgct gctcaaaccg ggcagcgacc gcagttcgca ggtggtgttg ctgggcaagg
    15601 tgatcggcga ggtcaccgcg ctgtcctacc gcgagcgcaa gacacacctg gccgccaccg
    15661 tgctggccac cctggacggc ctgcgcgccg agtacgaggc ggtgatctgc gagggcgccg
    15721 ggtcgccgac cgagatcaac ctgcgcgcca acgacatcgc caacatgggc ctggcccgtg
    15781 cggcgaacct gccggtgctg gtggtcggcg acatcgaccg cggcggcgtc ttcgcgcacc
    15841 tgttcggcac cctggccctg ctcgacccgg cggaccaggc cctggtcagc ggcttcgtca
    15901 tcaacaagtt ccgcggcgac cccgccctgc tggacccggg tctgcgccag ctcaccgcgc
    15961 tcaccggccg cccggtgcac ggtgtgctgc cctggcggga ggagctgtgg ctggacgccg
    16021 aggactcgct ctcctacgcc gccgacgggg tggtcggccg tccggccgcg ccggtcggcg
    16081 agcagtggct gcgcgtcgcc gtgccgcgcc tgccccggat ctccaacgcc accgacgtcg
    16141 aggcgctggc cggtgaaccc ggtgtctcgg tccgcttcgt caccgagccc tcccgcctgg
    16201 ccgacgccga cctggtcgtc ctgcccggct ccaagtccac cgtcgccgac ctggactggc
    16261 tgcgccgcac cggcctggcc gcggccatca cccggcacgc ggccgccggc ctgccggtca
    16321 ccggcatctg cggcggctac cagatgctgg ccgccacctt gcacgatccg gtcgagtcca
    16381 gggcgggcac cgtcgacggc ctcggcctgc tcgacctgga catcgagttc cacccggaca
    16441 aaaccctggc caacccggcc ggcgccgcgc tcgggcaccc ggtgcgcggc tacgagatcc
    16501 accacggccg cccggcccgc cgcgccgagc acctcgcccc gctgatcacc ctgcccgacg
    16561 gcacggggga gggcgcgctg cacggaccga tcgcgggcac gcactggcac ggcctgttcg
    16621 agaacgacgg gttccgccgc gacttcctga cctgggccgc gaccagggca ggccgcaccg
    16681 gcttcacccc ggccccggac accgatttcg ccgccgcccg cgccgcccag ctggacctgc
    16741 tgggcgacct ggtcgccgac cacctggaca ccgacgcggt gcaacgcctg ctggaatccg
    16801 gcgcaccgcg aggactcccg gccatcccac ccggcgcacc gcccagttgc tgacccgaag
    16861 gcgcgagcga gcgccccggc ttcgcccgcc gggggcgtag agtgcgggta ccggaggcag
    16921 gccgaattca gcgctctcgc tgagcaaacc tcgggcgtac gccgaacccg gcgcctgagc
    16981 gctgccggag atgggatgac cgacatgacg tcgggatcca cgcaacgcca ggacttccag
    17041 ccccccgccg ccggcgccgt ccagcacgag ccacgagtcc aggtgaagcc ggtggacgcg
    17101 agtcccggtt tcctcgacgg cggctggtgg cccaacagca tggacctcgg ccgggccctg
    17161 cccgcactgc tgtccgcgct gcgggaacgg ctcggaccgg tcagccgggt cacctaccac
    17221 ctggagcact ggctgcccgc gccccggcgg ctcaccgtcg gcggccgggt ggtgcggctg
    17281 gagggctatc gctcgcccga tccgcgcacc atcacggtga ccggccagtc cgggcaacgg
    17341 cttgtgctgc tggtggtgcc gccggagacg accgagtccg aggcccgccg cgtgctggac
    17401 ctgacggccg gggcggacaa ccgggacagc gccgcgagcc tgctcggggt gatcagcccg
    17461 gcggagcagg actgaccacc gccgcgcggg gacggcccgg ggtcagccca gtcgctcgtg
    17521 caggaacgcc accacctggt ctctggccgc catcgcggcg ttgccttccc gcacttccct
    17581 ggtcagcacc gaatgcgcgt tcgacttgaa cccgtccgcg ttgcccggcc gcgagtccag
    17641 ttccaccacc cggaacgcct cgcccagccg gtcggtcaac gtccggaacc gctcgcccgg
    17701 gaccagccgg tccgcgctga accgcaaccc catcaggcac agcccggact ccaccgtgcg
    17761 cgccgcgatc cgggacagtt ccgcctccga catgcccgga tccgccttgc gccgggcccc
    17821 cagcggcagc ggcagtgacg gctgactgcc caccggggcc agcaccacct catccaccgc
    17881 cgcggccagc gcgaaaccgc cggtgaagca catgccgatc acgccgacgc cgggtcctgg
    17941 ggtgcgctcg ttcaggtccc gcgcgaccgc gcgcaggtag tcgctgaacg gccgtttcgc
    18001 gttggtggcg aaggcccgga actccgcgga cacacacgcc ttggccgcca ccggcagccc
    18061 ggtgcgggtg ctctccggcg cgcccggcgt gccgaaggcg gacacgatca gcacggtgaa
    18121 cccgttgtcc accaggtgat cggcgaagcc cagcaccgag ggcgtcatgc cggggatctc
    18181 cggcagcacc accacaccgg ggccgctgcc cttctcgaag cagtcatagg tggaaccggc
    18241 cgcggtgaac ggcgcgcgcc gccacccggt caggtccgtc tcgggcgccc cggcggtcat
    18301 ggcaactcct cggtgtggtc ggacccggct tggccgcagt ctggccagct tgatcacggt
    18361 tgtacaccag cggcggggcg gccgttcgcg cacaccgcgg gcacccccgc tgctccattc
    18421 ggcggtttgc tgtcacgttc cagaaccaag ccccgccgag ccgttgacgc ggccgtagcc
    18481 cgtctgtaac tcttgcctcc cgccgcgcaa aaatctgaca ttgcaccggt aattccgtac
    18541 agagtcccgt gaattcctgc gcaacgccgc gcatgacctc ctccctggct gccctgccgt
    18601 ggggatgaga aacaagagga ccgcaatgag agtgcagcgc tccctgtccc gacccgtcgc
    18661 cttcctagcc acgttgtgcc tggtcatcct gggtggtccc gtagtggcca ccgccgcccc
    18721 cgcaacggat ctcgcggtcc ggcagccggt ggcggccagc agcgccgagg ccgcgcacac
    18781 cgcccgcgcc ctcaccgacg gcgaccaggg cacctactgg cagagcgcgg gcgccgcgct
    18841 cccgcagtgg gcccaggtgg acctcggcgg tgcgtcggtg atcgaccagg tcaagctgaa
    18901 actgcccgcg ggctgggcga aacgcaccca gcgactggcc gtgcagggca gcagggacgg
    18961 ggtcggcttc gacaccctgc tcacctcccg ggcgcacacc ttcgacccgg ccgccggcaa
    19021 cacggtgagc atcgacctgc ccgcgaccac cacccgctac ctgcgcctgg aggtcagcgc
    19081 gaactccggc gaccgggccg cgcagctggc cgaggtcgag gtccgccggg ccacaccgtc
    19141 cacagtggac atcgcagcgg cggccacctt caccgcgagc agccagaacc agaactacac
    19201 cgcggccaac gcgggcgacg gtaatccggg cagctactgg gaaagcgtca acaacgcctt
    19261 cccacaatgg atccaggccg atctgggcgc ctcgatcagc gtcaaccggc tggtgctcaa
    19321 gctcccggcg aactgggaga cccgcgcgca gaccctcacc gtgcgcggca gcgagaacgg
    19381 cgacaccttc accgaactgc tcgccggccg ggcgcacacc ttcagcccgc aggcacagaa
    19441 cacggtgacc atcaccttca acgccaccac cacccggtac ctgcggctgg agatcaccgc
    19501 gaacaccgcc tggcccgccg cgcagctggc cgagttcgag atctacggcc ccaccaccgg
    19561 cgacacccag gcccccaccg cgcccggcgg gctcgcgcac acccagcccg gcgtggacca
    19621 gatccggctg acctggaccg cggccaccga caacgtgggc gtcaccggct acgacatcta
    19681 cgccaacaac accctgcgca gcagcgtggc cgggaacgtg ctgacctaca ccgacaccca
    19741 gccggtgaac gcgaccgtca cctaccacgt gcgggcgcgc gacgccgccg gcaacgcctc
    19801 acccaacagc aacacggtca cccgcaccgg ctcggacgcg ggcaccaacc tggcccaggg
    19861 caagccgatc accgcctcct cgcacgtgca caccttcgtc gcgggcaacg ccaacgacaa
    19921 cgacgtgcgc acctactggg agggcggcgc cggctacccg aacacactca ccgtgtcgtt
    19981 gggcgccaac gccgacctca gctcggtggt gctcaagctc gaccccagca ccgcctgggg
    20041 ccgccgcacc cagaccctgg aagtccttgg ccgggaccaa agtggcggtg cgttcacctc
    20101 gctcgccgcc tccgctcagc acgtcttcga ccccgcagcc ggcaacacgg tgaccatcgg
    20161 ggcccgcggc cgggccgcgg acatccagct ccgcttcacc ggcaacaccg gcgcgcccgc
    20221 cggtcaggtg gccgaattcc aggtgctcgg cgtgcccgcg ccgaacccga acctgaccgt
    20281 caccggcagc tcctggaccc cggccacccc ggtggaaacc gatccggtgc gcctgagcgc
    20341 caccgtgcgc aacgcgggca gcgccgccgc gggcgccacc agcgtcggct tctacctggg
    20401 cgacaccaag gtcggcaccg ccgccgtggg cgcactggcc gcgggggcga gcagcaccgt
    20461 caccgccgac ctcggtccgc gcgacgcggg cagctacccg gtgaccgcca aggtcgacga
    20521 ggacaacaag gtcctcgaac agaacgagac cgacaacagc cacaccaacg ccagccacct
    20581 agtagtgaac ccggtgtcca gctcggacct ggtcgccgcc gcggtgagct ggaccccgaa
    20641 caacccgtcc cccggcgccg cggtgaactt cgcggtgtcc atccgcaacc agggcagcat
    20701 cgcctcggcc gcgggcgcgc acggcatcac gctgaacgtg ctggacgcca acgggaccgt
    20761 ggtgcgcacg ctcaccggca cgcacaacgg cgtcatcacc ccggacagca ccaccgcccc
    20821 ggtgaacctg ggcagctggc cgtccgcggc cggacggcac tcggtccggg tcgtgctcgc
    20881 cgatgacgcg aacgagctgc cggtcaagcg cgccaacaac accagcaccc aggccctgtt
    20941 cgtcggccgc ggcgcgaaca tgccgtatga catgtatgag gccgaggacg cggtcaccgg
    21001 cggcggcgcg tccgtggtcg gcccgaaccg caccatcggc gacctcgccg gcgaggcatc
    21061 cggccgccgc gcggtcaccc tcaacagcac cggcagcttc gtcgagttca ccaccagggc
    21121 cgccaccaac accctggtga ctcgcttctc catcccggac tccgccggtg gtggcggtat
    21181 cgacgccacg ctcaacgtct acgtcaacgg ccagccacac cagccgctga acctgacctc
    21241 caagtactcc tggctctacg gcgcggaggc cagccccggc aactcgccgg gcgcgggcgc
    21301 gccccggcac atctacgacg aggcgcacct caagctcagc ggcaccatcc cggccggcag
    21361 caagatcagg ctgcagaagg acagcggcaa cagcaccaac tacgcgatcg acttcatcaa
    21421 caccgagcag gtcgcgccga tcgccaaccc ggacccggcc aagtacaccg tgcccaccgg
    21481 gtttggccac caggacgtgc agaacgcgct ggacaaggtc cggatggaca ccacagggaa
    21541 tctcgtcggg gtgtacctgc ccgccggtga ctaccagacc agcagcaagt tccaggtcta
    21601 cggcaaggcg gtcaaggtca ccggcgccgg accctggttc accaggttcc acgcaccctc
    21661 cactcaggac aacaccgata tcggcttccg cgccgagggc accgcgggcg gctcctcctt
    21721 cgccaacttc gcctacctcg gcaactacac ctcgcggatc gacggtcccg gcaaggtgtt
    21781 cgacttcagc aatgtcgccg acatcgtcat cgacaacatc tggaacgagc acatggtgtg
    21841 cctgtactgg ggcgccaaca ccgaccggat caccatcaag aactcccgga tccggaacat
    21901 gttcgccgac gcgatcaaca tgaccaacgg cagcaccgac aaccacgtgg tcaacaacga
    21961 ttcccgggcc agcggcgacg acagcttcgc gttgttctcc gcgatcgacg ccggtggcgc
    22021 ggacatcaag aacaacgtct acgagaacct gacctccacg ctgacctggc gggcggccgg
    22081 catcgcggtc tacggcggct acgacaacgt cttccgcaac atctacgtgg ccgacaccct
    22141 cgtttactcc gggatcacca tctcctcgct ggacttcggc tatccgatga acgggttcgg
    22201 gccgggaccg acgaagttcg agaacatctc catcgtccgg gcgggcggcc acttctggaa
    22261 cggccaaacc ttccccggca tctgggtgtt ctccgcctcc aaggtcttcc gcaacatccg
    22321 ggtgtccgat gtggacatca tcgacccgac ctacagcggg atcatgttcc agaccaagta
    22381 caccggcagc tccccggaga acccgatcac cgacacggtg ttcaccaacg tctccatctc
    22441 cggggcgcgc aagagcggtg acgccttcga cgccaagtcc ggcttcgccc tgtgggccaa
    22501 cgagctgccc gaacccggtc agggtccggc ggtcggctcg gtcaccttca ccaacctgcg
    22561 gctgtccggc aaccac
//
