LOCUS       NZ_JALMDK010000003     24014 bp    DNA     linear   CON 13-SEP-2024
DEFINITION  Crossiella sp. S99.2 NODE_3_length_988117_cov_87.532730, whole
            genome shotgun sequence.
ACCESSION   NZ_JALMDK010000003
VERSION     NZ_JALMDK010000003.1
KEYWORDS    WGS; RefSeq.
SOURCE      Crossiella sp. S99.2
  ORGANISM  Crossiella sp. S99.2
            Bacteria; Actinomycetota; Actinomycetes; Pseudonocardiales;
            Pseudonocardiaceae; Crossiella.
REFERENCE   1  (bases 1 to 988117)
  AUTHORS   Gonzalez-Pimentel,J.L.
  TITLE     From North to South: A Spanish map of bacteria producing bioactive
            compounds in show caves
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 988117)
  AUTHORS   Gonzalez-Pimentel,J.L.
  TITLE     Direct Submission
  JOURNAL   Submitted (18-APR-2022) Agroquimica, Microbiologia Ambiental y
            Conservacion de Suelos, Instituto de Recursos Naturales y
            Agrobiologia, Av. Reina Mercedes 10, Sevilla 41012, Spain
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: 2021
            Assembly Method                   :: SPAdes v. 3.14.1
            Genome Representation             :: Full
            Expected Final Version            :: No
            Genome Coverage                   :: 200x
            Sequencing Technology             :: Illumina NovaSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_023094165.1-RS_2024_09_13
            Annotation Date                   :: 09/13/2024 06:26:08
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.8
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 9,481
            CDSs (total)                      :: 9,422
            Genes (coding)                    :: 9,365
            CDSs (with protein)               :: 9,365
            Genes (RNA)                       :: 59
            rRNAs                             :: 2, 1 (5S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 1 (5S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 57
            CDSs (without protein)            :: 57
            Pseudo Genes (ambiguous residues) :: 0 of 57
            Pseudo Genes (frameshifted)       :: 8 of 57
            Pseudo Genes (incomplete)         :: 50 of 57
            Pseudo Genes (internal stop)      :: 4 of 57
            Pseudo Genes (multiple problems)  :: 4 of 57
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 12:32:50
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 949852
            Orig. end                         :: 973866
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            JALMDK010000003.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..24014
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene"
                     /region_number="7"
                     /rules="(PT_phytoene_like or phytoene_synt or Lycopene_cycl
                     or Lycopene_cycl_fung or T1TS or T1TS_KS or T2TS or TS_UbiA
                     or TS_Pyr4)"
                     /tool="antismash"
     cand_cluster    1..24014
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /kind="single"
                     /product="terpene"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..24014
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:14014](+)"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..14014
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
     misc_feature    465..479
                     /note="TFBS match to IolR, Regulator of the inositol
                     catabolism, confidence: medium, score: 19.79"
                     /tool="antismash"
     misc_feature    complement(995..1010)
                     /note="TFBS match to RutR, Regulator of the pyrimidine and
                     purine metabolism, confidence: weak, score: 19.86"
                     /tool="antismash"
     misc_feature    1443..1456
                     /note="TFBS match to LexA_variant_2, Repressor of DNA
                     damage response, confidence: weak, score: 17.87"
                     /tool="antismash"
     gene            complement(1964..2620)
                     /locus_tag="MZC64_RS15580"
                     /old_locus_tag="MZC64_15590"
     CDS             complement(1964..2620)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1195: IclR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020671788.1"
                     /locus_tag="MZC64_RS15580"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MZC64_15590"
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="WP_247756362.1"
                     /transl_table=11
                     /translation="MGRGVLEGAFLLLEEILDTEECGLSELAARTGLPKATVHRLLDQL
                     VRLGAVQRSEGRYRMGARMFRFGTGWRSGADLRAAALHPLRQLASALPGAGVSVAVPDG
                     EDTLILGALGGETDDVVPLRAGLKYPAEGLWRVLIRSAGEGDGVLRVPEATCAQELAGV
                     SAVVRTRSGEVCGAVSAWVLDQRRLPAMSAVVRHTAGLVSGQLARIRRPTWPLNS"
     gene            2756..3322
                     /locus_tag="MZC64_RS15585"
                     /old_locus_tag="MZC64_15595"
     CDS             2756..3322
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="MZC64_RS15585"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="MZC64_15595"
                     /product="hypothetical protein"
                     /protein_id="WP_247756361.1"
                     /transl_table=11
                     /translation="MRLARLGSLFMTAAAAVALLTGAAGAATAGPAAASHSDGFEGDPW
                     TRWEKGSEGDARAEGNYGQGTARTGRNNAFLWSAHGHSSVRLPINIASWPKSSCKASIW
                     GNPVADAAHPGPRGAQVELQVWDPNGWRLLGTTAPWLNDGSYQRVITPPLDLNGVNKVY
                     VQAIFGNNSGAGKFVRLDDMSFECS"
     gene            complement(3425..4105)
                     /locus_tag="MZC64_RS48675"
                     /old_locus_tag="MZC64_15600"
     CDS             complement(3425..4105)
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1016: LuxR family
                     DNA-binding response regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: protein motif:HMM:NF012422.5"
                     /locus_tag="MZC64_RS48675"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MZC64_15600"
                     /product="LuxR C-terminal-related transcriptional
                     regulator"
                     /protein_id="WP_247756360.1"
                     /transl_table=11
                     /translation="MATISRTVETTTGQPGLDRIAVAVHAADRRLADQLEPALAVPREL
                     CLLAASESALADVVLVISEMVTDSLVGELIAMSAAARRHGQCFVLVAGPLRERHLPRLF
                     GAGVVSILPYRDVTAHQVVRTVLASHSGQAVLPAGLTRWLVEETRFMRTNLLATQGVTA
                     GGLTVREVEVIRLIAQGEETAGIASRLSYSERTIKKIVKDLMSRLDLRNRAHAVSYALR
                     VGAI"
     misc_feature    complement(4132..4146)
                     /note="TFBS match to MexT, Global virulence regulator,
                     confidence: weak, score: 17.51"
                     /tool="antismash"
     gene            complement(4298..4927)
                     /locus_tag="MZC64_RS15595"
                     /old_locus_tag="MZC64_15605"
     CDS             complement(4298..4927)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1215: TetR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013672820.1"
                     /locus_tag="MZC64_RS15595"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MZC64_15605"
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="WP_247756358.1"
                     /transl_table=11
                     /translation="MGEPAGLRERKKQRTREAIAEAAIALFLDRGFDQVSVAEVAAAAE
                     VSKRTLFKYFPSKEDLVVQRFADHQDESARYVRARVAGESPLAALERGWLDALERQDPN
                     TGLCDLPEVVRFYRLITGTESLTARLRRYVEESAALLADALVAAGYPPRRARLVAVQAG
                     ALETLLMQENSVQIAAGRSAAEVYPEAVAALTEAFALLRTGAEPPR"
     gene            5014..6495
                     /locus_tag="MZC64_RS15600"
                     /old_locus_tag="MZC64_15610"
     CDS             5014..6495
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1050: monooxygenase FAD-binding"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020416946.1"
                     /locus_tag="MZC64_RS15600"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MZC64_15610"
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="WP_247756356.1"
                     /transl_table=11
                     /translation="MRTQVIVVGAGPTGLMLAHELVLAGVSTLVLERLTEPNPQSRAGS
                     LQPRTAEVLDLRGLLAPLLDGVPLTGLIGGHFAALPVPLDCTPWQTRYAAPVPVSQGRL
                     EGFLEQRVIAGGGTVRRGAEVVAVSQREDGVQVSTAAGDTLHADYVVACDGAHSTVRKH
                     LGMAFPGQPATVRSVVADVVLTDRPVGMREGGRHFSEMVRGANGYWTVLHPLGDGVYRF
                     IFGNFTEPSPPRDRPVTEAEARAALQAVYGPEVDLTEIRAASRFSDASRQLTDYRAGRV
                     FFAGDAAHIHLPVGGQGVNLGVQDAMNLGWKLAAQLTGRAAEGLLDTYQAERHPVAAGV
                     LANTQAQGVLLNPGSAADVAALRELMTGLLRLPEVNRHLSGMVSGLDIRYTVAETEDDL
                     IGRRMPDLDLVADGGADRVAALSHAGRGLLLRFDEGSPATVEGWTDRVDQVQAKAVAWR
                     GAVLVRPDGHVCWAGAGDSGLRAALTRWFGAPTER"
     gene            complement(6626..7282)
                     /locus_tag="MZC64_RS15605"
                     /old_locus_tag="MZC64_15615"
     CDS             complement(6626..7282)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009073371.1"
                     /locus_tag="MZC64_RS15605"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MZC64_15615"
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="WP_247756355.1"
                     /transl_table=11
                     /translation="MTDLIRRWQQGWSACRGWAPPVESHGALDFLLGQPDRHRELITLH
                     VDAVPDSVRPLADVVATQEKPTLLTVPTHHPDEVEQVLREAGLTLRAYREWIMTREVAT
                     HPQRPAPAGYTCQTTVTGRVISVEVRHESGDLAASGLAAVIGTDTVPDKIVTTDAHRRR
                     GLGSVVMGALMTEAANQGASTGILFASPDGERLYTALGWVTEATVVMATSPRHAA"
     misc_feature    7267..7281
                     /note="TFBS match to VqsM, Regulator of quorum-sensing
                     signalling systems, confidence: medium, score: 17.99"
                     /tool="antismash"
     misc_feature    complement(7332..7348)
                     /note="TFBS match to NuR, Nickel-responsive regulator,
                     confidence: weak, score: 23.65"
                     /tool="antismash"
     misc_feature    complement(7332..7348)
                     /note="TFBS match to HexR, Glucose-responsive regulator,
                     confidence: weak, score: 17.12"
                     /tool="antismash"
     gene            complement(7338..7550)
                     /locus_tag="MZC64_RS15610"
                     /old_locus_tag="MZC64_15620"
     CDS             complement(7338..7550)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="MZC64_RS15610"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="MZC64_15620"
                     /product="hypothetical protein"
                     /protein_id="WP_247756353.1"
                     /transl_table=11
                     /translation="MPEPTLTRELAKLTRDERVVRFSSLRVAALRATRAGRPDFEFRLR
                     AGCAESRIYRTTYLDRFFCGPLIAT"
     gene            complement(7668..9425)
                     /locus_tag="MZC64_RS15615"
                     /old_locus_tag="MZC64_15625"
     CDS             complement(7668..9425)
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1041:
                     transcriptional regulator, SARP family"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: protein motif:HMM:NF013124.5"
                     /locus_tag="MZC64_RS15615"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MZC64_15625"
                     /product="AfsR/SARP family transcriptional regulator"
                     /protein_id="WP_247756351.1"
                     /transl_table=11
                     /translation="MDIGPLKQRCLLGLLALQPDRVVTRDEIIDVLWGVNPPRTCAGLV
                     HSYVSRLRRGLQPGREGRARGSVITAVRDGYRMPVEAGQLDLLEFDELVHHAERAAEDA
                     GAALELFDSALHRWRGPVLVDLGSRLRQHPAAIALSQRRLAALLTYTDLSIALGRHEPA
                     VERLRPLAHDEPLHEGLHARLMLALAGCGRQAEALRLFTEIRARLAEELGVGPGAEIQE
                     AHLRVLRGELPLPPVTVSRATPRDPGAPVPTQLPSDTPGLAGRDRYLAQLDAFLAGADN
                     TGAGTVNAAAIVGAAGVGKTTLAVHWAHRASGRFPDGQLFVNLHGNAPVSASRVLARFL
                     RALGVPADEVPAEADEAAALYRTLLASRKVLVVLDNAAHPAQIRPLLPGSPSCFVVITS
                     RHRLGSLAASDGAHLLDLDVLSPVDSLRALARMLGPDRVRAEPKAAAELTRLCAHLPLA
                     LSAAAANLVNHPHHRIADYVLALHNGNRLAALEVDSDQHLSLRAAFDHSYGTLDLPTQR
                     LFRRLSLVHGGFSGETVAALIDGTSHDADHMLDRLAAQHLIRAAPAGSYTLDDLLRLYA
                     TERAQAEDA"
     misc_feature    9400..9409
                     /note="TFBS match to ToxT, Regulator of MSHA biosynthesis,
                     confidence: weak, score: 13.82"
                     /tool="antismash"
     misc_feature    complement(9591..9607)
                     /note="TFBS match to ZuR_variant_2, Zinc-responsive
                     repressor, confidence: weak, score: 16.41"
                     /tool="antismash"
     misc_feature    complement(9593..9605)
                     /note="TFBS match to MatP, Cell cycle regulator,
                     confidence: weak, score: 19.27"
                     /tool="antismash"
     misc_feature    9595..9605
                     /note="TFBS match to HypR, L-hydroxyproline utilization
                     repressor, confidence: weak, score: 19.14"
                     /tool="antismash"
     gene            10001..11695
                     /locus_tag="MZC64_RS15620"
                     /old_locus_tag="MZC64_15630"
     CDS             10001..11695
                     /GO_function="GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: T2TS"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF024640.5"
                     /locus_tag="MZC64_RS15620"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MZC64_15630"
                     /product="prenyltransferase/squalene oxidase
                     repeat-containing protein"
                     /protein_id="WP_247756349.1"
                     /sec_met_domain="T2TS (E-value: 2.5e-33, bitscore: 111.1,
                     seeds: 58, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNSTELTGRASAGVHKAVDHLYTRQRPDGAWTDRLSSSTVSTALG
                     LLALAKADRERYRERLDRGLAWLRAHQRADGGWSMADAHPPSSPGMTAFAIAACHELDP
                     EGNRERIAKGFAFIEANGTDAVIPGMRGPGPKTWPAAAPFALSLVGLRDITEQPTLPVE
                     VMLLPPKLRNKVSIGMPAVLALGLMQARVLPASPPRRLLQRLAQPRALAWLRAVMAPNG
                     GVEECPMLSALIFLGLQAADLGPDLQQGSLDYLLDTQREDGSWAIDRDLEIAVTCYAVH
                     ALAEHTDVAADPRLRPTRDWLLSTQWTEPFRPLKIPAGGWSWNVPSGWPESEDTAVVLS
                     TLGLLGLDREHPGVAAGLRWLRVRQNRNGSWSEWVRNSFILNDKPCTGVTAHVLMAMHQ
                     HNEPRSRWAPVDRALRWYQKDQLPDGSLPSLWFRDGTHGTAKVLETYAELGIPRDPVAQ
                     RAKQWLWDNQAPSGGWPLTVQTSAPGETAEETAWAVYSLLRAGESPWDPRVLRAVDWLL
                     ARQDEQGSWAPAPTGLYFEDLCYSDDLITHTYTLRALARWLRQAERA"
     gene            11692..12999
                     /locus_tag="MZC64_RS15625"
                     /old_locus_tag="MZC64_15635"
     CDS             11692..12999
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) p450"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1034: cytochrome P450"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF012296.5"
                     /locus_tag="MZC64_RS15625"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MZC64_15635"
                     /product="cytochrome P450"
                     /protein_id="WP_247756347.1"
                     /sec_met_domain="p450 (E-value: 1.5e-59, bitscore: 197.7,
                     seeds: 50, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTGLPPGPRTPVLAQTVLSAVRPLAFAESCRRKYGDLFTIKVFPV
                     GTVVCAADPAVIRRAVTAESSTLLAGDANRVMDFVVGPRSVLLLDGPEHVRCRQVLLPP
                     FRGPSVAAYQDTIAEITAEAVRDWPAGVPVRLMPRMQHLTLEIMMRVVFGITDLRRLAG
                     LRALVPQLLHMNPAVVLFPLLRKDWGRWSPGGKFARVRDAVDEILFAEIARRRREDTDS
                     TDVLSLLLRMRHADGQPATDEELRDNLITVLAVGHETTATTLSWAFERLVRHPESLARL
                     ESELDAGEYTYLDAVINETLRVRPVVGDIARILAAPATIGGYRLPAGIMLALSLGLLHS
                     SPERYPEPAAFRPERFLDQPPGPELFLPFGGGPHRCLGAAFAMTTMRTVIATVLARTRP
                     RAAAPGPERQRARGPVLAPARGAEVVLHRRTAFRTR"
     gene            13010..14014
                     /locus_tag="MZC64_RS15630"
                     /old_locus_tag="MZC64_15640"
     CDS             13010..14014
                     /EC_number="2.5.1.-"
                     /GO_function="GO:0004659 - prenyltransferase activity
                     [Evidence IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /GO_process="GO:0008299 - isoprenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: PT_FPPS_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1182: Polyprenyl synthetase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF012568.5"
                     /locus_tag="MZC64_RS15630"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MZC64_15640"
                     /product="polyprenyl synthetase family protein"
                     /protein_id="WP_247756346.1"
                     /sec_met_domain="PT_FPPS_like (E-value: 3.1e-53, bitscore:
                     176.5, seeds: 145, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MQSADPRPELVLAGLAEAAEEKLRTRWSRTSSLLSTMCHYALVPS
                     GKLFRPILLLESACAVGGSAEMVLPAAVGAECGHVASLIHDDIIDGDELRRGRRSVHSR
                     FGAGNAIVAGDALIFDLFAGLAECRWTGVPDSRVAAALEAVARCGLDLCRGQSMEEELC
                     RGLRFDLDSYLTMIRLKTAAFFQGACESGAILAGGTPEEVEALSRYALALGTAFQIQDD
                     ILGYTNTTEEMGKDNTSDSRNGRLTLPVILAYRNGGHPERRLLRQALTGEEDLGHRHEL
                     ILDILDRTGALAAASKMAWHYAEASGTALLRLPPSPSRDRLALFGQLAIDRDR"
     gene            complement(14142..15119)
                     /locus_tag="MZC64_RS15635"
                     /old_locus_tag="MZC64_15645"
     CDS             complement(14142..15119)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ubiA"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF013226.5"
                     /locus_tag="MZC64_RS15635"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MZC64_15645"
                     /product="UbiA family prenyltransferase"
                     /protein_id="WP_247756344.1"
                     /sec_met_domain="ubiA (E-value: 7.7e-25, bitscore: 83.5,
                     seeds: 9, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNARRVLLAHLEICRPDSMFYAGLVGLAGAVLAARLGQTDPETWR
                     LFAAWAAPTCGWIASLYGGDYFDRELDATAKPHRPIPSGRMSPRTAFTGMVLTIALGLV
                     FAIVLNPLNLVLGAIAVVSGISYSRTFKARGIAGNLMRGVPTALAFLVGTTASTAIPPW
                     ELLPLALAFWLHDSASNLVGALCDTDSDREGGYRTYPVRHGDAASLRLLTVLNGLWIAL
                     AVGWPLVLAGQLDLGWLWPFLALALPLCVLCQLRLTRAPRPIPRLAALKAHEILVGERL
                     ILATGFIAAAGRPALALAVLLPAALLTTVARAIMRQRDHPTLRR"
     gene            15146..16336
                     /locus_tag="MZC64_RS15640"
                     /old_locus_tag="MZC64_15650"
     CDS             15146..16336
                     /GO_function="GO:0071949 - FAD binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1087: hypothetical
                     protein"
                     /gene_kind="other"
                     /inference="COORDINATES: protein motif:HMM:NF013646.5"
                     /locus_tag="MZC64_RS15640"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MZC64_15650"
                     /product="FAD-dependent monooxygenase"
                     /protein_id="WP_247756342.1"
                     /transl_table=11
                     /translation="MTPLAVIAGAGVAGLTAAVALSQAGWRVRVFDRDPVLEPLGAGLG
                     LTPNALRALDVLGLGDAVRDRGAVQETGGIRRQDGRWLARSDLAFIRARFGDPVLGLHR
                     RDLITLLANALPEGTLRTGVTVTSATPGGHDRLSLVRTTLGELTAQLVVAADGIGSKLR
                     SALFPAHPGPVYAGYTSWRMVVPMPDYPVAATETWGRGTRFGVMHLPDGLLHLSANSVA
                     PPRQRARDERAEVLARFGNWHAPIPDLLAAVRPGEVLHHDVAELVRPLPTFHSGRIVLV
                     GDAAHAMTPNIGPACLAMEDAVTLGLLLPAARESELAAALAGYTAIRLPRAVALARRSR
                     RVGLAGQWTWPPAVAARNLGIRLGGLLPSSVTARALDGSVDWWPPARPPAARSARG"
     gene            complement(16257..17489)
                     /locus_tag="MZC64_RS15645"
                     /old_locus_tag="MZC64_15655"
     CDS             complement(16257..17489)
                     /GO_function="GO:0004497 - monooxygenase activity [Evidence
                     IEA]"
                     /GO_function="GO:0005506 - iron ion binding [Evidence IEA]"
                     /GO_function="GO:0016705 - oxidoreductase activity, acting
                     on paired donors, with incorporation or reduction of
                     molecular oxygen [Evidence IEA]"
                     /GO_function="GO:0020037 - heme binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) p450"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1007: cytochrome P450"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020640395.1"
                     /locus_tag="MZC64_RS15645"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MZC64_15655"
                     /product="cytochrome P450"
                     /protein_id="WP_247756340.1"
                     /sec_met_domain="p450 (E-value: 9.2e-24, bitscore: 79.7,
                     seeds: 50, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTADPATQARAFPFVVEGLRLDPLYDRLRREEPVLRVRLPFGEQA
                     WLVTRYQDAKFVLVDQRFSREAMHGRDVPRSMPYNSTTGIVTMDPPQHSRVRTLVARAF
                     TQRRAEALRPRTIEVAESLLDDLVAAGPVQDLVAGYSLPLTNTVISEVLGIPRDDQDQF
                     REWSDLALSSAVSPERSEEVAGQMWDYLEGLLRRRRTERTDDVLGAMVTKGEADLSEPE
                     LIMLAMTVLVAGYETTASHIPNFAFVLLTNQDLLDALRGDPELMPAAVEELLRWVPLEA
                     GAGLPRYATEDVEVGGVLIRAGEPVLVDPAAANHDPAAFGCPERVDFHRPENPHLAFSH
                     GPHHCLGASVARMVLQVALDRLLARLPELHLAVPADELVWKTQQLIRGLTALPVAWRAA
                     TSPPNHPAPAR"
     gene            complement(17486..18190)
                     /locus_tag="MZC64_RS15650"
                     /old_locus_tag="MZC64_15660"
     CDS             complement(17486..18190)
                     /EC_number="2.1.-.-"
                     /GO_function="GO:0008168 - methyltransferase activity
                     [Evidence IEA]"
                     /GO_function="GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF019846.5"
                     /locus_tag="MZC64_RS15650"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MZC64_15660"
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="WP_247756338.1"
                     /transl_table=11
                     /translation="MTDRYTYMAQYHELFALPYKEPTQRAVAKAVADCANGVLEMGAGT
                     GLVTETIADASAGEVFAVEPAAPMRAVLMSRLARRPDLQRRVTVMPMSALEVRLPVRVD
                     AVVLISMLLCFSPAERQKLWQVCADSLNPGGLLLQDRPEPSSAEAIPPAAGSLQVGRAR
                     YDIEYEGRPVREGVLRLSWSYRITVGDEPGIEEREEIDAYPVTESELDAELAAAGFDRA
                     DAPDDLLGWRLR"
     gene            complement(18183..20132)
                     /locus_tag="MZC64_RS15655"
                     /old_locus_tag="MZC64_15665"
     CDS             complement(18183..20132)
                     /GO_function="GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /GO_function="GO:0031419 - cobalamin binding [Evidence
                     IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /GO_function="GO:0051536 - iron-sulfur cluster binding
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF04055"
                     /gene_functions="other (smcogs) SMCOG1277: Radical SAM
                     domain protein"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007032956.1"
                     /locus_tag="MZC64_RS15655"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MZC64_15665"
                     /product="KedN5 family methylcobalamin-dependent radical
                     SAM C-methyltransferase"
                     /protein_id="WP_247756336.1"
                     /sec_met_domain="PF04055 (E-value: 2e-13, bitscore: 46.8,
                     seeds: 518, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTRTRVWLIQQGIWEMALESMPLAAGYLKATALQDERLAAAMDIR
                     IINFDGGKTLFGMASELFAEEAPDIIAFSVLGWNYRSFAALAETFKQINPDGWVVFGGN
                     HVANQAKRVFGMFPDVDIVVNGEGELTFCDILHAHLDGKARNELGGILGISFQSGYGGF
                     VTTEERPRIEDLDTIASPVLTGTLELTDDEGNFRYDVALMETNRGCPYRCSFCYWGGAV
                     GQRVRAFSRERLRQEVELFAKHKVHTIVMCDANFGMLPIDLEFVEDVIEIRQRLGFPKS
                     IETSWAKNKSKLFYQIVSAMKEAGLHSSFTLALQTLNPDALEGMQRRNMKVNDWESLAE
                     WLGKEGMACYAELIWGAPGETVESFMEGYDRLANHVSRVAVYPMLILPNTAYAEKRAEH
                     GLITVRGNNDDFMYLIAHNTMTPQDNRYMHRFIFFSRLVAENPVFRFLWGPLRELGGIT
                     QSETIRSLIDWFERSTHPAAEPFQHGLNSSFTDSDVLGPVVEYVYGTVEAKEELRRWWR
                     ESLLPRVPSEHATLLDTAFEYDLLTLPAYSSPGREPSPLYANETLPLVEVEGDLFHVRH
                     HITLACDVPAMCLALRRGESYAHTVGEQETSLYYKAGARNFVTSTNHEEIVYYMGRLAR
                     EMFSDNRRGVVSHD"
     gene            complement(20176..21333)
                     /locus_tag="MZC64_RS15660"
                     /old_locus_tag="MZC64_15670"
     CDS             complement(20176..21333)
                     /GO_function="GO:0004497 - monooxygenase activity [Evidence
                     IEA]"
                     /GO_function="GO:0005506 - iron ion binding [Evidence IEA]"
                     /GO_function="GO:0016705 - oxidoreductase activity, acting
                     on paired donors, with incorporation or reduction of
                     molecular oxygen [Evidence IEA]"
                     /GO_function="GO:0020037 - heme binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) p450"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1007: cytochrome P450"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF012296.5"
                     /locus_tag="MZC64_RS15660"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MZC64_15670"
                     /product="cytochrome P450"
                     /protein_id="WP_247756335.1"
                     /sec_met_domain="p450 (E-value: 5.8e-16, bitscore: 54.0,
                     seeds: 50, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MGAPPFPFARPSVTEPPVEYARLRAQEPVSRVTTNSGEPAWLVTR
                     YEDIRFVLSDLRFGVRAPGAAAATEDSLFQDPPGHTRLRRLVSKAFTVRGVEALRPKVQ
                     DLAKRLAGDLAAAGPPADLVEIFAFPMSIGVITELLGVPVVDQADFRRWSEAILSLDAF
                     SQEEVMAAGKSLDEYCAGLIADKQRNPGPDLLSDLISVREEDNDRLNERELLTMAESIL
                     IAGYVTAGNTIGLGALTLLTHPQDYLDLVEDPSLVPGAIEEILRYASEIGGLVRIAQED
                     VRIGEVLIKAGDTVIAPPACANRDEQRFPDSGRFDRTRPANLHLAFGHGVHHCLGAAVG
                     RLELQEAFTALTQTFPTLRLAVPVAELPQRAGLLDQGPSALPVAW"
     misc_feature    21345..21361
                     /note="TFBS match to ZuR_variant_2, Zinc-responsive
                     repressor, confidence: weak, score: 16.66"
                     /tool="antismash"
     gene            complement(21348..22538)
                     /locus_tag="MZC64_RS15665"
                     /old_locus_tag="MZC64_15675"
     CDS             complement(21348..22538)
                     /GO_function="GO:0004497 - monooxygenase activity [Evidence
                     IEA]"
                     /GO_function="GO:0005506 - iron ion binding [Evidence IEA]"
                     /GO_function="GO:0016705 - oxidoreductase activity, acting
                     on paired donors, with incorporation or reduction of
                     molecular oxygen [Evidence IEA]"
                     /GO_function="GO:0020037 - heme binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) p450"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1007: cytochrome P450"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF012296.5"
                     /locus_tag="MZC64_RS15665"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MZC64_15675"
                     /product="cytochrome P450"
                     /protein_id="WP_247756333.1"
                     /sec_met_domain="p450 (E-value: 1.9e-21, bitscore: 72.1,
                     seeds: 50, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSAPERAPAVSLPLAQPSITEPPADYARLQAENPVARVVTENGTH
                     AWMVTRYEDVRFVLADPRFSIRFAGAAGDNAEDGPEESLFQDPPGHSRLRRLVGRAFTA
                     RRMAELRPAVRRTAERLAEAMARDYPPAELVTDFAFPLSINVISELLGVPTPDRAEFRA
                     WSEAVVSMTAHTPEQIGAAWQNLNGYVAELIEAKRQEPGSDLMSALIEVRDTDDDRLST
                     GELRTMAVTLLVAGHVSTVNAITLGMLTLLTNRAQYDRLVADPGLIEGAVEEILRCQFG
                     KRGLMRIAKEDVPLGSALIRKGDTVFAELGAANCDAELFAEPARFDITRPDNPHLAFGH
                     GIHHCLGAALGRMELQVTLEVLSSAFPLLRTVLPVERIPMRTGLLDQSPAALLVTW"
     misc_feature    complement(23190..23205)
                     /note="TFBS match to AfsQ1, Two-component system AfsQ1-Q2,
                     activator of antibiotic production, confidence: medium,
                     score: 17.11"
                     /tool="antismash"
     misc_feature    23534..23552
                     /note="TFBS match to LexA_variant_3, Repressor of DNA
                     damage response, confidence: weak, score: 19.02"
                     /tool="antismash"
     misc_feature    complement(23535..23553)
                     /note="TFBS match to LexA_variant_3, Repressor of DNA
                     damage response, confidence: weak, score: 19.21"
                     /tool="antismash"
ORIGIN
        1 ggtgtgcaac gcggtctgtg cgccgcggcc gcggacggcg agcagttcct cggggctgtc
       61 gatctcctcc atgagttcgg cggcgtaggc gcgcagtagt tcgtgccagg tgtagccgcc
      121 ggggcggatc tcctcgacca ggtgggcggc ggcgagttcg cggaagagcg cgtgtgcctt
      181 ggggatcggc agtgcggcca gggtggcgcc gatgcggacc tccatgacct ggccggggaa
      241 ccaggacagc agccggaaca tccgggccgc ttcggggctg agtgcgcggt aggaccagga
      301 caggatggag cggatgtcgc tgcggctgtc cgggccggcg aaggcgtcca ggccgccgtc
      361 ggtggcgtcg agttcggcgg ccaggtcggc cagccggaag gaggggtagc tggcggcgcg
      421 ggcggcgacc agggccagcg ccagcggcaa gcgggcgcag gtgcggacta tgtgttgcac
      481 tgcttcgggt tcggcggcca cccggggttc gccgaggcgg cgggacagga agctggtggc
      541 ctcggtgtcg ctgagcagtt ccaggggcac ggtgtgcgcg ccggtgccgg cgaccaggcc
      601 ggaaaggttg ccgcggctgg tgatgatggc cagcgagcgg gagctgccgg gcagcagtgg
      661 cagcacctgg cgggtgtccc gggcgttgtc gagcaggatc aggcagccgc ggtcggcgag
      721 cacgctgcgg tacaacgcgg tgagcgtgtc caggcggctg ggcagttgct gggtgggcac
      781 gccgagggag tccagcagga accacagcgc ttccatcggg tcgacctcgg tgtcgccgtc
      841 ctcaaagccg cgcaggtcca ggtggagctg gccgtccggg aagtgcgggg ccagccggtg
      901 cgcggcgcgg acggcgaagg tggtcttgcc cagtccgggc atgccgtgca cgaccaccac
      961 ccccggcgcg tcggtggcat ccggccggac cgcgttgatc aggcggtcca gttccgcttc
     1021 acggccggtg aacacgggca ggtccaccgg cagctgggcc gggatcaggg tgggggcggc
     1081 gggttcggga gtcgcggcgg gcggcggcgg ggccagcagc accggatcgc cttccaggat
     1141 gcgctggtac agctcgcgca tggccggcgc cgggtccacg ccgagctgat cgccgagccg
     1201 gcggcgcagc cggtcgtaaa cgctcagtgc ctcggcctgg cggcccgcgc ggcacaggca
     1261 gagcatgagc agctcgtgca accgctcccg caggggttcg gccgccgcgg ccatggccag
     1321 tgggtccagc aggtcggggc tgcggccgag gtcgagttcg agcgcggcca gctcctccag
     1381 cacggccagc cgccgctgcc ccagcctgcc gcgttcggac tcggcgaact ccgaggtcag
     1441 gtcggacatg ggttcgccct gccactcggc cagggcctgg tgcagatggg tggccgcgcc
     1501 ctcccggtca cctcgggcct tggcctgctc ggcggcgcgc acataatcac ggaaccggcc
     1561 caggtccagg gtctgcggcg gcacctgcag cgcgtagccg ccggtggtgg agtgcaccac
     1621 ctgctcaccc tgttcttctt ccagcgcgcg gcgcaggcgg tgcacgtagg tgcggatggt
     1681 gccgcgggcg gcgcgcggca cgtccaggcc ccacagcgcg gcggccatct cgtcggtgga
     1741 gaccatccgg ctgcgggcga gcagcaggat ggccagtgcg gtgcgctgct gcggcgatcc
     1801 gaggccgacg gcggcaccgt tccgccaggc ccggaccggt cccagcacgg cgaacttcag
     1861 tccctgggtc aagggagccc ctctgtgtcc gagctacgaa ccgggggcca atcgtagtac
     1921 cagaatgggc cgatcagcct aatcggcgtg cggtgtccgc gctctaggag ttcagcggcc
     1981 aggtcggtcg ccggatccgg gcgagctgtc cgctgaccag acccgcggta tgccgcacca
     2041 ccgcgctcat ggcgggcagt cgccgctggt cgagcaccca ggcggacacc gctccgcaga
     2101 cttctcccga ccgcgtccgc acgaccgcgc tgactccggc cagctcctgc gcgcaggtgg
     2161 cctcgggcac gcgcagcacc ccgtccccct cgcccgccga ccggatcagc acccgccaga
     2221 ggccctccgc ggggtacttc agcccggcgc gcagtggcac cacgtcatcg gtctccccgc
     2281 ccaacgcacc gaggatcagg gtgtcctcac cgtccggcac tgccacgctc accccggcgc
     2341 cgggcagggc ggatgccaac tgccgcaacg ggtgcagcgc cgccgcgcgc aggtccgcac
     2401 cgctgcgcca gccggtgccg aagcggaaca tccgcgcgcc catccggtac cggccctcgc
     2461 tgcgctgcac cgcgcccagc cggacgagct ggtccagcag gcggtgcacg gtggccttgg
     2521 gcaacccggt ccgggcggcc agttcgctga gcccgcactc ctcggtgtcg aggatctcct
     2581 caagcaacaa gaacgcgcct tccagcacac cccggcccac attgcctccc tgactcggcg
     2641 gcgacgataa cagcggtcca ctcagcggac cgaattcttt tccagcggat tccgccggga
     2701 cattctgggt gagccgcaag gcagcagatt ttctcagcga aaaaggggaa atctcatgcg
     2761 tttggctcga ttgggttcgc tgttcatgac cgcggcagcc gccgtggcac tgctcaccgg
     2821 cgccgcgggc gcggccaccg ccggaccggc cgccgcgagt cactccgacg gcttcgaggg
     2881 cgacccgtgg acccggtggg agaagggctc ggaaggcgat gccagggccg agggcaacta
     2941 cggtcagggc acggcccgca ccggccgcaa caacgctttc ctgtggtcgg cgcacggcca
     3001 ttcctcggtc cggctgccca tcaacatcgc cagctggccc aagtccagct gcaaggccag
     3061 catctggggc aacccggtgg ccgacgccgc gcacccgggc ccccgtggcg cgcaggtcga
     3121 actccaggtc tgggacccca acggctggcg gctgctgggc accaccgcgc cctggctcaa
     3181 cgatggcagt taccagcgcg tcatcacgcc gccgctggac ctcaacggcg tgaacaaggt
     3241 ctacgtccag gccattttcg gcaacaactc gggcgccggg aaattcgtcc gactggatga
     3301 catgtcattc gagtgcagct gatttagccc cagggaatgc cctttcggcc gcgaaatgcg
     3361 ctcgaaaggg cattccgccg gtctggccgc gtgcaccagg gctgtgccgt ggtgcacgcg
     3421 gccctcagat cgcgccaacg cgcagcgcgt aggagacggc gtgcgcccgg ttgcgcaggt
     3481 cgagacggga catcaggtcc ttgacgattt ttttgatggt tcgttccgaa tagctgaggc
     3541 ggctggcgat tccagcggtt tcctcgccct gggcgatcag ccggatcacc tcgacctccc
     3601 ggacggtcag gccgcccgcg gtcactccct gggtggccag caggttggtc cgcatgaacc
     3661 gggtttcctc gaccagccag cgggtcaggc cggcgggcag caccgcctga ccgctgtggc
     3721 tggccagcac ggtccggaca acctggtggg cggtgacatc ccggtacggc aggatgctga
     3781 ccaccccggc gccgaagagc cgcggcaggt gacgttcccg cagcggaccc gcgaccagca
     3841 cgaagcactg gccgtggcgc cgcgcggccg ccgacatcgc gatcagctca ccaaccaggg
     3901 agtcggtgac catttcactg atgaccagca ccacatctgc gagagcgctc tcacttgccg
     3961 cgagaagaca cagttcgcgc ggcaccgcga gcgctggttc gagctggtcg gccagtcgcc
     4021 ggtcggccgc gtgcacggcc accgcgatcc ggtccagccc aggctgtcct gtcgtcgtct
     4081 cgactgtcct gctgatcgtg gccacgctca tcgatggtgc ccttctccat catcgacgct
     4141 cccgatagcg ccgtgggatc aggaaacccg gcacctgtca acagctcgtc gacaagtcgt
     4201 agacggtcac cgcgacagct gaaacagcag ctcagccacc taacgtgcgc cactgccgac
     4261 gggcccgacc tcggcgggcg ccgccgaggt cgggccacta tcggggcggt tcagcccccg
     4321 tacgcagcag cgcgaacgcc tcggtgagcg ccgccaccgc ctccggatac acctccgccg
     4381 ccgaccgtcc cgccgcgatc tggaccgagt tctcctgcat cagcaacgtt tccagggcac
     4441 cggcctgcac cgcgaccagt cgcgcgcgcc ggggcgggta gccggccgcc accaacgcgt
     4501 cggccagcag ggccgcggat tcctcgacgt agcggcgcaa ccgggcggtc aggctctcgg
     4561 tgccggtgat cagccggtag aaccggacca cctcgggcag gtcgcacagc ccggtgttcg
     4621 ggtcctggcg ctccagcgcg tccagccagc cccgctccag cgcggccagc ggcgactccc
     4681 ccgccacccg ggcccgcacg taccgcgccg actcgtcctg atggtcggcg aaacgctgta
     4741 cgaccaggtc ttccttgctc gggaagtact tgaacagggt gcgcttggag acctcggccg
     4801 ccgcggccac ctcggccacc gagacctggt cgaagccgcg atccaggaac agcgcgatgg
     4861 ccgcttccgc gatggcctcg cgggtccgct gcttcttccg ctcgcgcagc cctgctggtt
     4921 cgcccattgg cacatcctag ccaactcgtg cacccagggc ataagtacac ctggtatatc
     4981 ttgataccga gtggaccttt tgaagggagt gtcatgcgga ctcaggtgat cgtcgtgggc
     5041 gccggaccga ccgggctgat gctggcgcac gagctggtgc tggccggggt gtccacgctg
     5101 gtgctggaac gactgaccga gccgaacccc cagtccaggg cgggcagcct ccagccgcgc
     5161 accgccgagg tgctggacct gcgcggactg ctcgcgccac tgctggacgg ggtgccgctg
     5221 accggcttga tcggcggcca cttcgccgcg ctgccagtcc ccctggactg cacgccgtgg
     5281 cagacccgct acgccgcgcc ggtgccggtc tcccaggggc ggctggaggg tttcctggaa
     5341 cagcgggtga tcgcgggcgg cggcacggtg cggcgcggcg cggaagtggt cgcggtcagc
     5401 cagcgcgagg acggcgtgca ggtcagcacc gccgccgggg acaccctgca cgcggactac
     5461 gtggtggcct gcgacggcgc gcacagcacg gtgcgcaaac acctcggcat ggccttcccc
     5521 ggtcaacccg ccacggtccg ctcggtggtc gccgatgtcg tccttaccga ccggccggta
     5581 ggcatgcgcg aaggcggtcg ccacttcagc gagatggtcc gcggcgccaa cggctattgg
     5641 accgtgctgc accccctggg cgacggggtc taccggttca tcttcggcaa cttcaccgag
     5701 ccgagcccgc ccagggaccg accggtcacc gaggcggaag cgcgcgccgc actgcaggcg
     5761 gtgtacggac cggaggtgga cctgaccgag atccgcgctg cctcccgctt ctccgacgcc
     5821 tcccgccaac tgacggacta ccgcgccggc cgggtcttct tcgccggcga cgccgcgcac
     5881 atccacctcc cggtcggcgg ccagggcgtc aacctgggcg tccaggacgc gatgaacctg
     5941 ggctggaaac tcgccgccca gctgaccggt cgggcggccg aggggctgct ggacacctac
     6001 caggccgagc gtcacccggt cgcggccggc gtgctggcca acacccaggc ccagggcgtg
     6061 ctgctcaacc cgggcagcgc cgcggacgtg gcggcgttgc gcgaactgat gaccgggctg
     6121 ctgcggctgc ccgaggtcaa ccggcacctg tccggcatgg tctccggcct ggacatccgc
     6181 tacaccgtgg ccgagaccga ggacgacctg attggccgac ggatgccgga tctggacctg
     6241 gtggccgatg gtggggcgga ccgggttgcg gcgctgagtc acgcgggtcg cgggctgctg
     6301 ctgcggtttg acgaaggcag cccggccacg gttgagggct ggactgatcg ggttgatcag
     6361 gtgcaggcga aggccgttgc ctggcggggt gcggtgctgg tccggccgga tgggcacgtg
     6421 tgctgggcgg gcgccgggga cagtgggctg cgggccgcac tcacccgctg gttcggcgcg
     6481 ccgaccgaac ggtaggtcgg gcgacgtggg ctggctcgac gtcccgaccg aacggttggt
     6541 cgagacgcgg gacgcaggct ggtctcgcgc gcgccgaccg aacagttggt cggggcgcgc
     6601 gaccaggccg gggcgcggga ccgggtcagg ctgcgtggcg ggggctggtg gccatgacca
     6661 ctgttgcctc cgtgacccag cccagggcgg tgtagagccg ctcgccatcc gggctggcga
     6721 acaggatccc ggtgctggcg ccctggttcg ccgcctcggt catcagggcg cccatcacca
     6781 cgctgcccag gccgcggcgg cggtgtgcgt cggtggtcac gatcttgtcc gggacggtgt
     6841 ccgtgccgat cacggcggcc aggccgctgg cggcgaggtc cccggactcg tgccggacct
     6901 cgaccgagat cacccggccg gtcaccgtgg tctgacaggt gtatccggcg ggagcggggc
     6961 gttgtgggtg cgtggccact tccctggtca tgatccattc gcggtaggcc cgcagggtca
     7021 ggccggcctc gcgcagcacc tgttcgacct cgtcggggtg gtgcgtcggg acggtgagca
     7081 gggttggttt ttcttgggtg gcaacgacat cggccagcgg gcggactgag tcggggaccg
     7141 cgtcgacgtg cagggtgatc agttcgcggt ggcggtcggg ctggccgagc aggaagtcca
     7201 gggcgccgtg ggactccacc ggtggcgccc agccccggca tgcgctccag ccctgctgcc
     7261 agcggcggat cagatcggtc atgcggcgtg tcctctcggt tcaggcggac cctaaccgcg
     7321 catccgtgct gttgcaacta ggttgcaata agaggtccgc agaagaaccg gtcgaggtag
     7381 gtggtgcggt agatcctgga ctcggcgcag ccggcccgga gccggaactc gaaatccggc
     7441 cggccggccc gggtggcccg cagcgccgca acgcgcagcg aactgaatcg cacgacccgc
     7501 tcgtcccggg tcagcttcgc cagttcgcgg gtgagtgtgg gctccggcat cgaggcgcgc
     7561 tcgcgcaact cctcgaagga tcgccgtcct ccccgggagc gggcctgccc gtcaactcgg
     7621 caggtgtgcc cgcccccggt ggggaaccgt cccggcgcgc gccgggctca ggcgtcctcg
     7681 gcctgagcgc gttcggtggc gtagaggcgg agtagatcgt ccagggtgta gctgcccgcg
     7741 ggggcggctc ggatgaggtg ctgggcggcg aggcggtcga gcatgtggtc ggcgtcgtgg
     7801 gaggtgccgt cgatgagggc ggcgacggtt tcgccggaga aaccgccgtg caccaggctc
     7861 aagcggcgga acaggcgttg ggtgggcagg tccagggtgc cgtaggagtg atcgaaggcg
     7921 gcccgcaggg acaggtgctg gtcgctgtcg acttccaggg cggccaggcg gtttccgttg
     7981 tgcagggcca gaacatagtc ggcgatgcgg tggtgggggt ggttgaccag gttggcggcg
     8041 gcggcactga gcgcgagtgg gaggtgggcg cagaggcggg tgagttcggc cgctgccttg
     8101 ggttcggcgc ggacccggtc ggggccgagc atgcgggcca gggcccgcag ggagtcgacc
     8161 gggctgagca cgtccaggtc gagcaggtgg gcgccgtcgc tggcggccag gctgccgagg
     8221 cggtgtctgc tggtgatcac cacgaagcag ctcgggctgc ccggcagcag ggggcggatc
     8281 tgggcggggt gggcggcgtt gtccagtact accagcactt tgcggctggc cagcagggtg
     8341 cggtagaggg cggcggcctc atcggcctcg gccgggacct catcggcggg gacgccgagg
     8401 gcgcgcagga atcgggccag cacgcggctg gccgagaccg gggcgttgcc gtgcaggttg
     8461 acgaagagct ggccgtccgg gaagcgaccg ctggcccggt gtgcccagtg cacggccagg
     8521 gtggtcttgc cgaccccggc cgcgccgacg atggccgcgg cgttgaccgt gcccgcgccg
     8581 gtgttgtccg ccccggcgag gaaggcgtcc agctgggcca ggtaccggtc ccgtccggcc
     8641 aggcccgggg tgtcactggg cagctgggtg ggtaccgggg cgcccggatc ccttggtgtg
     8701 gcacgggaaa cggtgaccgg gggcagcggc agctcgccgc gcagcacccg caggtgcgcc
     8761 tcctggatct ccgcgccggg acccacgccc agttcctcgg ccagccgggc ccggatctcg
     8821 gtgaacagcc gcagcgcctc ggcctgcctg ccgcagccgg ccagggcgag catcagccgg
     8881 gcgtgcagcc cctcgtgcag tggttcgtcg tgcgccagtg ggcgcagccg ttccaccgcg
     8941 ggttcgtgcc tgcccagggc gatggacaga tcggtatagg tgagcagtgc ggccaggcgg
     9001 cgctgggaca gtgcgatcgc ggccggatgc tggcgcagcc gggatccgag atcgaccagc
     9061 accgggccgc gccagcggtg cagggccgag tcgaacagtt ccagcgccgc gcccgcgtcc
     9121 tcggcggcac gttcggcgtg gtgcaccagc tcgtcgaatt ccagcaggtc cagctgaccg
     9181 gcttccaccg gcatccggta gccgtcgcgg accgcggtga tcaccgatcc tctggcccgg
     9241 ccctcgcggc cgggttgcag gccgcgacgc agccgggaga cgtaggagtg caccagtccg
     9301 gcgcaggtgc gcggtgggtt gacgccccag aggacgtcga tgatctcgtc ccgggtgacc
     9361 acccgatcgg gttgcagggc cagcaggccc aacagacatc gttgtttgag cggaccgatg
     9421 tccacctggc ggtgtgcctg gtagacggtg agcgggccga ggatgttcag ccgtagcggt
     9481 tttcggccac gaggcggggt gccgccacgt ggccggacct gttctcgccg gaggctgacc
     9541 tcggctcgtc cgtcccgtag ttctccgtct gatctcctgc ttaacgaacc atgttccaat
     9601 gtcacgcccg cagcccccag ccctggcgtt atgtcctccg accaccgcac gacctcaaca
     9661 agtggccaat actgccagag cgcggacgca ttgactatgc tcgccgctga tctcagttag
     9721 ttgattgcat cgaaataatc cggttatcgt gatcttaagg ttcgcggccc gctgccctcc
     9781 accgcgtttg cactgctgca gccgggtgca gccgaatgca gaacctccgg caacacccca
     9841 ggtcagggcc tgttgcaggg aggcaggcag acgggtgacg ggctccagtt ccggtccagc
     9901 cgggcggcca ggcgatctcg gtacggtaat gaccgggctc cttacctgaa acatcggcaa
     9961 attggggtgg ccgcgcatgg tttttgtgaa cgagccagtt gtgaattcca cggagctgac
    10021 cgggcgcgcg agcgcgggcg tgcacaaggc cgtcgatcat ttgtatacgc ggcaacgccc
    10081 ggacggcgcc tggacggacc ggctttcctc ctccacggtc tccaccgcac tgggtttgct
    10141 ggccctggcc aaggccgacc gggaacgcta tcgggagcgc ctggatcggg gcctggcctg
    10201 gctgcgcgcc caccagcgcg ccgacggcgg ctggagcatg gccgacgcgc acccgccgag
    10261 cagtcccggc atgaccgcct tcgccatcgc cgcctgccac gagctggacc cggagggcaa
    10321 ccgcgagcga atcgccaagg ggttcgcctt catcgaggcc aacggcaccg acgcggtcat
    10381 ccccggcatg cgcggccccg gcccgaaaac ctggcccgcg gccgcgccgt tcgcgctgtc
    10441 gctggtggga ctgcgggaca tcaccgagca gccgacgctg ccggtggagg tgatgttgct
    10501 gccgcccaag ctgcgcaaca aggtctccat cggcatgccc gcggtgctcg ccctcggcct
    10561 gatgcaggcc agggtgctgc cggccagtcc cccacgacga ctgctgcaac gcctggccca
    10621 gccgcgagcg ctggcctggc tgcgggcggt gatggcgccc aacggcggcg tggaggagtg
    10681 cccgatgctc tccgcgctga tcttcctcgg gttgcaggcc gccgacctcg gccctgacct
    10741 gcaacagggt tcgctggact acctgctcga cacccagcgc gaggacggct cctgggccat
    10801 cgaccgcgac ctggagatcg cggtgacctg ctacgccgtg cacgcactgg ccgagcacac
    10861 cgacgtggcc gccgaccctc ggttgcggcc caccagggac tggctgctct ccacccagtg
    10921 gaccgagccg ttccgcccgt tgaagatccc ggcgggtggc tggtcctgga acgtgccctc
    10981 gggctggccg gaatccgagg acaccgcggt ggtcctgtcc accctcggcc tgctgggtct
    11041 ggaccgcgag caccccgggg tggcggccgg actgcgctgg ctgcgggtgc ggcagaaccg
    11101 caacggctcc tggtcggagt gggtgcggaa ttccttcatc ctcaacgaca aaccgtgcac
    11161 cggggtcacc gcgcacgtgc tgatggccat gcaccagcac aacgagccac gctcgcgctg
    11221 ggcgccggtc gatcgcgcgc tgcgctggta ccagaaggac cagttgccgg atggctcgct
    11281 gccctcgctg tggttccggg acggcacgca cggcactgcc aaggtgctgg agacctacgc
    11341 cgaactcggc atcccgcggg atccggtggc acagcgggcc aagcagtggc tgtgggacaa
    11401 ccaggcgcct tccggtggct ggccgctgac cgtgcagacc agtgcgccgg gtgagaccgc
    11461 cgaggagacc gcgtgggcgg tgtactcgct gctgcgggcc ggggaatcgc cgtgggaccc
    11521 gcgggtgctg cgcgcggtgg actggctgct ggcccggcag gacgagcagg gcagctgggc
    11581 gcccgcgccg accggactgt acttcgagga cctctgctac agcgacgacc tgatcaccca
    11641 cacctacacg ctgcgcgcgc tggcccggtg gctgcgccag gccgagcggg catgaccggg
    11701 ctcccgccgg gtccgcgcac gccggtgctc gcgcagaccg tgctctccgc ggtgcggcca
    11761 ctggccttcg ccgaatcctg ccgccgaaaa tacggggatc tgttcaccat caaggtcttc
    11821 ccggtcggca ccgtggtgtg cgcggccgat ccggcggtga tccggcgtgc ggtgaccgcg
    11881 gagtcctcca ccctgctggc cggggacgcc aaccgcgtca tggacttcgt ggtcgggccg
    11941 cggtcggtgc tgttgctgga cggaccggaa cacgtgcgct gccgccaggt gctgctgccg
    12001 ccctttcgcg gccccagcgt ggccgcctac caggacacca tcgccgagat caccgccgag
    12061 gcggtgcggg actggccggc cggggtgccg gtgcggttga tgccgcggat gcagcacctc
    12121 accctggaga tcatgatgcg ggtggtcttc ggcatcaccg atctgcgccg gctggccggg
    12181 ttgcgcgcac tggtgccgca gctgctgcac atgaacccgg cggtggtgct gttcccgttg
    12241 ctgcgcaagg actggggtcg gtggagccct ggcggcaagt tcgccagggt gcgggacgcg
    12301 gtggacgaga tcctcttcgc cgagatcgcc cggcgccgcc gcgaggacac cgacagcacc
    12361 gatgtgctct cgctgctgct gcggatgcgg cacgccgacg ggcagccggc caccgacgag
    12421 gagttgcggg acaacctgat caccgtgctc gcggtcggcc acgagaccac cgcgaccacg
    12481 ctgtcctggg ccttcgagcg tctggtccgg cacccggaat cgttggcccg cttggaaagc
    12541 gagctggacg ccggtgagta cacctacctg gacgcggtga tcaacgagac gctgcgggtg
    12601 cggccggtgg tcggggacat cgcccggatc ctggccgcac cggccaccat cggcggttac
    12661 cggctgcccg ccgggatcat gctcgcgctt tcccttggcc tgctgcactc cagcccggag
    12721 cgctaccccg aaccggcggc gttccggccg gaacgcttcc tcgatcagcc gccgggaccg
    12781 gagttgttcc tgcccttcgg cggcgggccg caccggtgcc tcggcgcggc cttcgccatg
    12841 accaccatgc gcacggtgat cgccaccgtg ctggcgcgga cccggccccg ggcggcggcc
    12901 ccgggaccgg aacggcagcg ggcccgtggc ccggtgctcg cgcccgcccg aggggcggag
    12961 gtggtcctgc accgccgcac ggctttccgg accaggtgag gagcacaaca tgcagtccgc
    13021 tgatccccga cccgagctgg tgctggccgg gctggccgag gccgccgaag agaagttgcg
    13081 cacccgctgg tcccgcacgt ccagcctgct cagcaccatg tgccactacg cgctggtgcc
    13141 ctcgggcaag ttgttccggc cgatcctgct gctggaatcc gcctgcgcgg tgggcggttc
    13201 ggccgagatg gtgctgccgg ccgcggtcgg cgcggagtgc gggcacgtgg ccagcctgat
    13261 ccacgacgac atcatcgacg gcgacgagct gcgccgcggc cgccggtcgg tgcacagccg
    13321 gttcggcgcg ggcaacgcga tcgtggccgg ggacgcgctg atcttcgacc tgttcgccgg
    13381 gctggccgaa tgccggtgga ccggggtgcc ggacagccgg gtggccgccg cgctggaggc
    13441 ggtggcgcgc tgcgggctgg acctctgccg ggggcagagc atggaggagg agctgtgccg
    13501 gggcctgcgc ttcgacctgg actcctacct gaccatgatc cggctcaaga cggccgcgtt
    13561 cttccagggc gcttgcgaga gcggcgcgat cctggccggg ggcacgccgg aggaggtgga
    13621 ggcgctgtcc cggtacgcgc tggcgctggg caccgcgttc cagatccagg acgacatcct
    13681 gggctacacc aacaccaccg aggaaatggg caaggacaac accagcgaca gccgcaacgg
    13741 caggctgacc ctgccggtga tcctggccta ccgcaacggc ggccaccccg agcgcaggct
    13801 gttgcggcag gccctcaccg gcgaggagga cctgggccac cggcacgaac tgatcctgga
    13861 catcctggac cgcaccggcg cgctggccgc ggcgagcaaa atggcctggc actacgccga
    13921 agcctccggc accgccctgc tccgcctgcc cccctccccc agccgcgacc gcctggccct
    13981 gttcggccag ctcgccatcg accgcgaccg ttaacccccc tccccgagtg tcggccgaag
    14041 tgggacaccg agttggccca accggtacgc ccacttcggc caacttggcg tacgagttgg
    14101 gccaactcgg cgtacgagaa cggccgacac tcggggtggg gtcagcggcg gagggtgggg
    14161 tggtcgcgtt ggcgcatgat cgcgcgggcc acggtggtga gcagggcggc ggggaggagg
    14221 acggcgagtg cgagggcggg gcggccggcg gcggcgatga agccggtggc caggatcagg
    14281 cgttcgccga ccaggatttc gtgggccttc aacgcggcca ggcgcgggat cgggcggggg
    14341 gcccgggtga ggcggagttg gcagagtacg cacaggggca gggccagggc caggaacggc
    14401 cagagccagc ccaggtccag ctgtccggcc agcaccagtg gccagccgac ggccagggcg
    14461 atccagagtc cattgaggac agtcagcaaa cgcagcgagg cggcgtcgcc gtggcgcacc
    14521 gggtaggtcc ggtagccgcc ttcgcggtcg ctgtcggtgt cgcagagcgc gccgaccagg
    14581 ttggaggccg aatcgtgcag ccagaacgcc agtgccagcg gcagcagctc ccacggtggt
    14641 atcgcggtgc tcgccgtggt gcccaccagg aaggccagtg cggtcggcac cccgcgcatc
    14701 aggttcccgg cgatgccacg ggctttgaag gtgcggctgt aggaaatgcc ggacaccacc
    14761 gcgatcgcgc cgagcaccag attgagcggg ttgagcacga tggcgaacac caggccgagc
    14821 gcgatggtga ggaccatgcc ggtgaacgcg gtgcgcgggc tcatccggcc ggacgggatg
    14881 gggcggtgtg gtttggcggt ggcgtccagt tcgcggtcga agtagtcgcc gccgtacagc
    14941 gacgcgatcc agccgcaggt gggcgcggcc caggcggcga acaaccgcca ggtctccggg
    15001 tcggtctggc caaggcgggc ggccagcacg gccccggcca ggccgaccag cccggcgtag
    15061 aacatcgagt cggggcggca gatctccagg tgggccagca ggacccgtcg ggcgttcaca
    15121 cggactccct tccaggacaa cggtcatgac cccgctcgcg gtgatcgccg gggccggggt
    15181 ggccggactc accgccgcgg tggcgctgag tcaggcgggc tggcgggtgc gggtcttcga
    15241 ccgcgacccg gtgctggaac cactgggcgc cgggctcggt ctgaccccga atgccttgcg
    15301 cgccttggat gtgctcggtc tgggtgacgc ggtgcgggac cggggtgcgg tgcaggagac
    15361 cggcggcatc cgccgtcagg acggtcgctg gctggcccgc tcggacctgg ccttcatccg
    15421 ggcccgcttc ggggacccgg tgctcggcct gcaccggcgg gacctgatca cgctgctggc
    15481 caacgcgctg cccgagggaa cactgcgcac cggggtcacc gtcacctcgg ccaccccggg
    15541 tggtcacgac cggctttcct tggtgcgcac cacactcggc gagctgaccg cgcagctggt
    15601 ggtggctgcc gacggcatcg ggtccaagct gcggagtgcg ctgttcccgg cgcatcccgg
    15661 gccggtctac gccggctaca ccagctggcg gatggtggtg ccgatgccgg actatccggt
    15721 ggcggccacc gagacctggg gccgcggcac ccgtttcggc gtgatgcacc tgcctgacgg
    15781 cctgctgcac ctgtccgcga actcggtcgc gccgccccgg caacgcgcca gggacgaacg
    15841 cgccgaggtg ctggcccgct tcgggaactg gcacgcgccg atcccggacc tgctggccgc
    15901 ggtgcgaccg ggtgaggtgc tgcaccacga tgtggccgag ctggtccgtc cacttccgac
    15961 attccacagt ggacggatcg tgctggtcgg tgacgccgcg catgccatga cccccaacat
    16021 cggaccggcc tgcctggcca tggaggacgc ggtgaccctc ggtctgttgc tgccagctgc
    16081 cagggaatca gagctggccg cggccctggc cgggtacacc gcgatccggc tgccgcgggc
    16141 ggtggcgctg gcccgccggt cccgccgggt ggggctggcc ggccagtgga cctggccgcc
    16201 ggcggtggcc gcgcgcaatc tgggcatccg gctcggcggg ctgctgccga gcagtgtcac
    16261 cgcgcgggcg ctggatggtt cggtggactg gtggccgccc gccaggccac cggcagcgcg
    16321 gtcagcccgc ggatgagctg ctgggtcttc cacaccagct cgtccgcggg caccgccagg
    16381 tgcaattcgg gcaggcgggc cagcagccgg tccagcgcga cctgcagcac catccgggcc
    16441 accgaggcgc ccaggcagtg gtgcgggccg tggctgaagg ccaggtgcgg gttctccgga
    16501 cggtggaagt ccacccgctc cggacagcca aacgccgccg gatcgtggtt ggccgcggcg
    16561 ggatccacca gcaccggttc accggcgcgg atgagcaccc cgcccacttc gacgtcctcg
    16621 gtggcgtacc ggggcagccc ggcgcctgct tccaggggca cccagcggag gagttcctcc
    16681 accgcggccg gcatcagttc cgggtcgccg cgcagggcgt cgagcaggtc ctggttggtg
    16741 agcagcacga aggcgaagtt ggggatgtgc gaggccgtgg tctcgtaccc ggcgaccagc
    16801 acggtcatcg ccagcatgat cagttccggc tcggaaaggt cggcctcgcc cttggtgacc
    16861 atcgcgccga gcacgtcgtc ggtgcgttcg gtgcggcggc ggcgcagcaa accctccaaa
    16921 tagtcccaca tctgcccggc gacctcctcg gatcgctcgg gactgaccgc tgaggacagg
    16981 gccaggtccg accattcgcg gaactggtcc tgatcatccc gcgggatgcc gagcacctcc
    17041 gagatcaccg tgttggtcag cggcagcgag taacccgcca ccaggtcctg caccggaccg
    17101 gcggcgacca ggtcgtccag gaggctctcg gcgacctcga tcgtcctggg gcgcaaggct
    17161 tccgcccggc gctgggtgaa ggcgcgggcg accagggtgc gtacccggct gtgctgcggc
    17221 gggtccatgg tcacgatgcc ggtggtggag ttgtagggca tggagcgcgg cacgtcccgg
    17281 ccgtgcatgg cctcccggga gaaccgctgg tcgaccagca cgaatttggc gtcctggtag
    17341 cgggtgacca gccaggcctg ttcgccgaag ggcaggcgca cccgcagcac cggttcctcc
    17401 cggcgcagcc ggtcatagag cgggtccagg cgcaggcctt ccacgacgaa ggggaaggcc
    17461 cgcgcctggg tggcgggatc ggcggtcatc gcaggcgcca gcccagcaga tcgtccggcg
    17521 cgtcggcccg gtcgaacccg gccgcggcca gttcggcgtc cagttccgat tcggtcaccg
    17581 ggtaggcgtc gatctcctcg cgttcctcga tccccggctc gtcgccgacg gtgatccggt
    17641 aggaccagct cagccgcagc acgccctcgc gcaccgggcg gccctcgtac tcgatgtcgt
    17701 agcgggcccg gccgacctgg aggctgcccg cggcgggcgg gatggcctcg gcggaggagg
    17761 gttcgggccg gtcctgcaac aacaatccgc cggggttgag cgaatccgcg cagacctgcc
    17821 agagtttctg ccgctctgcc ggggagaagc agagcagcat gctgatcagc actaccgcgt
    17881 ccacccgcac cggcaaccgc acttccagcg cgctcatcgg catgacggtg acccggcgct
    17941 gcagatcggg cctgcgggcc agccgggaca tcagcacggc gcgcatcggc gcggccggtt
    18001 cgaccgcgaa cacctcgccg gcactggcat cggcgatggt ctcggtgacc agtccggtgc
    18061 cggcgcccat ctccagcacg ccgttggcgc aatcggccac cgccttggcc accgcacgct
    18121 gggtgggttc cttgtacggc agggcgaaga gttcgtggta ctgggccata tacgtgtaac
    18181 ggtcagtcat gggataccac gcctctccgg ttgtcactga acatctcccg cgccagcctg
    18241 cccatgtagt agacgatctc ctcgtggttg gtggaggtca cgaagttgcg ggcgcccgcc
    18301 ttgtagtaca gcgaggtttc ctgctcgccc acggtgtgcg cgtaggactc gccgcggcgc
    18361 agcgccaggc acatcgcggg cacgtcacag gccagcgtga tgtgatggcg cacgtggaac
    18421 aggtcgcctt cgacctccac cagcggcagg gtttcgttgg cgtacaacgg cgagggctcc
    18481 cggccgggac tgctgtaggc gggcagggtg agcaggtcgt actcgaacgc ggtgtccagc
    18541 agggtcgcgt gctcgctcgg caccctcggc agcagcgact cgcgccacca gcggcgcagc
    18601 tcttccttgg cctccacggt gccgtagacg tactccacca ccgggccgag cacatcggag
    18661 tcggtgaagg agctgttcag cccgtgctgg aagggttcgg ccgccggatg ggtgctgcgc
    18721 tcgaaccagt cgatcagcga gcggatggtc tcggactggg tgatgccgcc gagttcgcgc
    18781 agcgggcccc acaggaagcg gaacaccggg ttctccgcga ccaggcggga gaagaagatg
    18841 aaccgatgca tgtaccggtt gtcctgcggg gtcatcgtgt tgtgcgcgat gaggtacatg
    18901 aagtcgtcgt tgttgccgcg cacggtgatc agcccgtgtt cggcccgttt ttccgcgtag
    18961 gcggtgttgg gcaggatcag catcgggtag accgcgaccc gggagacgtg gttggccagc
    19021 cggtcatagc cttccatgaa ggactcgacg gtctcccccg gcgcgcccca gatcagttcg
    19081 gcgtagcagg ccatgccttc cttgccgagc cattcggcca ggctctccca gtcgttgacc
    19141 ttcatgttgc gccgctgcat gccttctagg gcatcggggt tgagggtttg caacgccagg
    19201 gtgaaggagc tgtgcagccc ggcttccttc atggcgctga cgatctggta gaagagcttg
    19261 gacttgttct tggcccagga ggtctcgatg ctcttgggga aaccgagccg ttgccggatc
    19321 tcgatgacgt cctcgacgaa ttccaggtcg atgggcagca tgccgaagtt ggcgtcgcac
    19381 atgacgatgg tgtgcacctt gtgcttggcg aacagctcca cttcctggcg cagccgttcc
    19441 cgggagaagg cccgcacccg ctgcccgacc gcgccgcccc agtagcagaa ggagcagcgg
    19501 taggggcagc cgcggttggt ctccatcagc gccacgtcgt agcggaagtt gccctcgtcg
    19561 tcggtgagtt ccagggtgcc ggtgagcacc ggggaggcga tggtgtccag gtcctcgatg
    19621 cgcgggcgtt cctcggtggt gacgaatccg ccgtagccgg actggaagga gatgcccagg
    19681 atgccgccga gttcgttgcg ggccttgccg tccaggtgcg cgtgcaggat gtcgcagaag
    19741 gtcagctcgc cctcgccgtt gaccacgatg tccacgtccg ggaacatgcc gaagacccgt
    19801 ttggcctggt tggccacgtg gttgccgccg aagaccaccc agccgtccgg gttgatctgt
    19861 ttgaaggtct cggccagcgc ggcgaaggac cggtagttcc agcccagcac ggagaaggcg
    19921 atgatgtccg gcgcctcttc ggcgaagagt tcgctggcca tgccgaagag ggttttgccg
    19981 ccgtcgaagt tgatgatccg gatgtccatg gcggcggcca gccgctcgtc ctgcaacgcg
    20041 gtcgccttga ggtacccggc ggccagcggc atggattcca gggccatttc ccagattccc
    20101 tgctggatca gccacacccg tgtccgcgtc atgggctccg tcctcacctc agtgtccgaa
    20161 gtagacagtg cgtgctcacc aggcgaccgg cagcgcgctg gggccctggt cgagcaggcc
    20221 ggctcgttgc gggagttccg ccactggcac ggccagccgc agggtgggga aggtctgggt
    20281 cagcgcggtg aaggcttctt ggagttcgag ccgtccgacc gcggcgccca ggcagtggtg
    20341 cacgccgtgc ccgaaggcca ggtgcaggtt ggccgggcgg gtgcggtcga agcggccgga
    20401 gtccgggaat cgttgctcgt cccggttggc gcaggccggt ggcgcgatca cggtgtcccc
    20461 ggccttgatc agcacctcgc cgatccgcac gtcctcctgc gcgatccgca ccaggccgcc
    20521 gatttccgag gcgtagcgca ggatctcctc gatcgcgccg ggcaccagcg acgggtcctc
    20581 gaccaggtcg aggtagtcct gcgggtgggt gagcagggtg agcgcgccca gaccgatggt
    20641 gttgccagcg gtgacgtacc cggcgatcag gatgctctcc gccatggtga gcagttcccg
    20701 ttcgttgagc cggtcgttgt cctcttcccg caccgagatg aggtcgctca acaggtccgg
    20761 cccggggttg cgttgtttgt ccgcgatcag cccggcgcag tactcgtcca ggctcttgcc
    20821 cgcggccatc acctcctcct ggctgaacgc gtccagcgac aggatcgcct ccgaccagcg
    20881 ccggaagtcg gcctggtcga ccactggcac gccgagcagt tcggtgatca ccccgatgga
    20941 catcgggaag gcgaagatct ccaccaggtc cgcgggcggt ccggccgctg ccagatcccc
    21001 ggcgagtcgc ttggccaggt cctgcacctt ggggcgcaag gcttccaccc cgcgcacggt
    21061 gaacgccttg gacaccagcc gccgcaaccg ggtgtgtccc ggcgggtcct ggaacagcga
    21121 gtcctcggtg gccgcggccg cacccggcgc gcgcacgccg aagcgcagat ccgagagcac
    21181 aaaacggatg tcctcgtacc gggtgaccag ccaggccggt tccccggagt tggtggtgac
    21241 ccggctgacc ggctcctggg cccgcagccg cgcgtactcc accggcggtt cggtgacgga
    21301 cgggcgggcg aacgggaagg gcggtgcccc catcggcgtc tccttcgtta ccaggtcacg
    21361 agcagggcgg ctgggctctg gtcgagcagg ccggtgcgca tcgggatgcg ttccaccggc
    21421 agcacggtcc gcagcaacgg gaaggccgag ctgagcacct ccagggtgac ctggagttcc
    21481 atccggccca gcgcggcgcc caggcagtgg tggatgccgt ggccgaaggc caggtgcggg
    21541 ttgtccggcc gggtgatgtc gaagcgggcc ggttcggcga acagctccgc gtcacagttg
    21601 gccgcgccca gctcggcgaa gacggtgtcg cccttgcgga tcagcgccga acccagcggc
    21661 acgtcctcct tggcgatgcg catcaggccg cgtttgccga actggcagcg caggatctcc
    21721 tccaccgcgc cctcgatcag cccgggatcg gcgaccaggc ggtcgtactg ggcgcggttg
    21781 gtcagcaggg tgagcatgcc cagggtgatc gcgttgaccg tgctgacatg tccggccacc
    21841 agcagggtga ccgccatggt gcgcagttcc ccggtgctga gccggtcgtc gtcggtgtcc
    21901 cgcacctcga tcagcgcgct catcaggtcg ctgccgggtt cctggcgctt ggcctcgatg
    21961 agttcggcca cgtagccgtt gaggttctgc caggccgcgc cgatctgctc gggggtgtgc
    22021 gcggtcatgc tgaccacggc ttcggaccag gcgcggaact ccgcccggtc cggcgtgggc
    22081 acgccgagca gttcgctgat cacgttgatg gacaacggaa aggcgaagtc ggtgaccagt
    22141 tcggcaggcg ggtagtcccg cgccatcgcc tcggccagcc gttcggcggt acgccgcacc
    22201 gcgggtcgca gctcggccat ccggcgggcg gtgaaggccc ggccgaccag gcggcgcaac
    22261 cggctgtgcc ccggcggatc ctggaacagc gactcctccg gcccgtcctc ggcgttgtcc
    22321 ccggccgcgc cggcgaagcg gatgctgaag cggggatcgg cgagcacgaa ccggacgtcc
    22381 tcgtagcggg tcaccatcca ggcgtgcgtg ccgttctcgg tgaccaccct ggccaccggg
    22441 ttctccgcct gcagccgggc gtagtccgcc ggtggttcgg tgatcgaggg ctgggccagc
    22501 ggcagcgata ccgccggggc acgctcgggt gcgctcatcc acgtctcctc acaccgccgc
    22561 cggggatccg gaatcgagtc ctgacgctag agaaccgcgc tggtcatgcg gctgcaccgg
    22621 cactggagca gccgggggcc cgcgtccagt tctggtgcag tccggcgcca agcggacctc
    22681 cgtagggtcc gggaccgaca tcgccttggg ctctgtgccc agtggacgga ggcgcaccaa
    22741 gatgacgacc gtggcactgg tggagatcca ctcctggcac agcttcctac cgctggtctc
    22801 gggctacttg cagagttatg cccgccagga cgagacgatc gcggagcggt acgagttcga
    22861 gatcctgtcc cggcacactt ccgacggccg ggtcgccctg gtggccgagc tggccgcgct
    22921 ggacagcgac atctacgcgt tcagttgcta catctggaac ggcacgctgg tccgcgaggt
    22981 gctggaggac ctggtccggt tgcggcccaa cgcccagtac ctgctcggcg gcccgcaggt
    23041 gatgaaccac ggcgaggact acatcccggc cggggcgcac aacgtggcgg tgtgcaacgg
    23101 cgaaggcgag atcaccttcc tggagtacct gcgcgaactg gcgggcgata ccccggatct
    23161 gggccgggtg cccgggttga gcttccgccg ggacggccgg gtgaccacta ccctgcccgc
    23221 ggcccggatc aaggaactca ccgaggtgcc gagtccgttc gtggccaacc tgttcaccga
    23281 ttcgacctac cacgtggcgg tgctggagac caaccgcggc tgcccgttcc gctgcggatt
    23341 ctgctactgg ggcgcggcca ccaacgacaa ggtgcaccgc ttcgagatgg accgggtcaa
    23401 ggccgacatc gagtggatcg ccaagaacaa catctacgcg gtgatgatcg ccgacgccaa
    23461 ctggggcctg tccgcgcgcg atgtggagct gaccgagtac atcgtggagt gcaaggagaa
    23521 gtacggcttc ccgtactggg tgaccatcca atcggccaag aacagcccgg agcgggtgtc
    23581 caagatcgtg gacatcctgt tgcgcggcgg gctgatcacc cgccagccga tctccctgca
    23641 aagtgtcagc gacgaggcgc tcaccctgat cgagcgcaag aacatcaagc gggagaccta
    23701 ctccgaactc cagcgcgacc tgcgggcccg caacatcccc tccttcatcg agctgatctg
    23761 gccactgccc ggggaaaccc tggcgtccta tgtggacgga atcgtgcagc tgtgccgcac
    23821 cggcgcggac atgatcaacg tgtacccgca gctgttgctg cacaacacgc cgatctacga
    23881 acagcgggag atcttcggcg tggtcaccga gcgggtgccc aacccggtgg gcgaggccga
    23941 attggtggtg cgcaccaagt gggtcaaccg ggagcagtac gacgagggcg tgtggttctg
    24001 gtacgcgctg ctgt
//
