LOCUS       NZ_CP095550            20915 bp    DNA     circular CON 11-MAY-2024
DEFINITION  Metabacillus endolithicus strain KCTC 33579 chromosome.
ACCESSION   NZ_CP095550
VERSION     NZ_CP095550.1
KEYWORDS    RefSeq.
SOURCE      Metabacillus endolithicus
  ORGANISM  Metabacillus endolithicus
            Bacteria; Bacillota; Bacilli; Bacillales; Bacillaceae; Metabacillus.
REFERENCE   1  (bases 1 to 5052055)
  AUTHORS   Lee,K. and Son,H.
  TITLE     Metabacillus endolithicus type strain genome analysis
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 5052055)
  AUTHORS   Lee,K. and Son,H.
  TITLE     Direct Submission
  JOURNAL   Submitted (11-APR-2022) Bio Health Science, Changwon National
            University, Changwondaero, Changwon, Gyeongnam 51140, South Korea
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: Miniasm v. 0.3
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 69.5x
            Sequencing Technology             :: Oxford Nanopore MinION
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_023078335.1-RS_2024_05_11
            Annotation Date                   :: 05/11/2024 05:30:11
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 5,521
            CDSs (total)                      :: 5,322
            Genes (coding)                    :: 4,799
            CDSs (with protein)               :: 4,799
            Genes (RNA)                       :: 199
            rRNAs                             :: 16, 15, 15 (5S, 16S, 23S)
            complete rRNAs                    :: 16, 15, 15 (5S, 16S, 23S)
            tRNAs                             :: 146
            ncRNAs                            :: 7
            Pseudo Genes (total)              :: 524
            CDSs (without protein)            :: 523
            Pseudo Genes (ambiguous residues) :: 0 of 524
            Pseudo Genes (frameshifted)       :: 474 of 524
            Pseudo Genes (incomplete)         :: 58 of 524
            Pseudo Genes (internal stop)      :: 17 of 524
            Pseudo Genes (multiple problems)  :: 23 of 524
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 08:11:14
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 1581870
            Orig. end                         :: 1602785
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP095550.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..20915
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene-precursor"
                     /region_number="8"
                     /rules="(PT_FPPS_like and not PT_HPP)"
                     /tool="antismash"
     cand_cluster    1..20915
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_FPPS_like and not PT_HPP)"
                     /kind="single"
                     /product="terpene-precursor"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..20915
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:10915](-)"
                     /cutoff="10000"
                     /detection_rule="(PT_FPPS_like and not PT_HPP)"
                     /neighbourhood="10000"
                     /product="terpene-precursor"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..10915)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="(PT_FPPS_like and not PT_HPP)"
                     /neighbourhood="10000"
                     /product="terpene-precursor"
                     /protocluster_number="1"
     misc_feature    374..388
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence:
                     medium, score: 22.68"
                     /tool="antismash"
     gene            complement(524..751)
                     /locus_tag="MVE64_RS08515"
                     /old_locus_tag="MVE64_08515"
     CDS             complement(524..751)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="MVE64_RS08515"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="MVE64_08515"
                     /product="hypothetical protein"
                     /protein_id="WP_247345521.1"
                     /transl_table=11
                     /translation="MHKTKIFVAGCLFSSLFSSAWYINERVKREYVETIAFEDSDIQLT
                     NTETPIELLTEEANVFEKFRPREYVRVVLR"
     gene            950..3355
                     /locus_tag="MVE64_RS08520"
                     /old_locus_tag="MVE64_08520"
     CDS             950..3355
                     /GO_function="GO:0051139 - metal cation:proton antiporter
                     activity [Evidence IEA]"
                     /GO_process="GO:0098662 - inorganic cation transmembrane
                     transport [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010676393.1"
                     /locus_tag="MVE64_RS08520"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MVE64_08520"
                     /product="Na+/H+ antiporter subunit A"
                     /protein_id="WP_247345523.1"
                     /transl_table=11
                     /translation="MTLLHVAILSPFLLAILIPFLYKYFRNIHTGWFVLGLPILLFVYF
                     IQFLDSTMHGDQISYTANWIPSLGINFTAYIDGLGLLFALLISGIGALVVLYSIYYLSK
                     EKEQLNTFYVYLLMFMGAMLGVVLSDNLIVLYTFWEFTSLSSFLLIGYWYHREKSRYGA
                     QKSMLITIFGGLLMLGGFIMLYMMTGTYSIREIVGQVPEISQHELFVPALILILFGAFT
                     KSAQFPFYIWLPDAMEAPTPVSAYLHSATMVKAGIYLVARFSPVFSGTPEWFWIVSSFG
                     IFTMFWGSFNAVKQTDLKGILAFSTVSQLGMIMSMLGVGSAALALESIDDSYYTVATLA
                     AIFHLINHATFKGSLFMVVGIIDHETGTRDIRKLGGLMSLMPITFTISIIGAFSMAGLP
                     PFNGFLSKEMFFTSMIRVMEMDVFNIETIGLLFPIIAWVGSIFTFIYSMVLVFKTFTGK
                     YQPEKLKKKPHEAPIGMLISPIILASLVVIFFFFPNILAYTIIEPAMASIIPGLLGDEG
                     HFHVHIYPWHGFTVELFMTIGVIALGIIGYLSLTKWRSVYRLVPEKLTLNKGYDAALHQ
                     LDRSSFRLTRFYMTGFIRDYLAYIFTFFILILGTALVATGGFTFSLAGTAPIGVYEAVL
                     AFVMVVGTVTVLFSKSRLTAIIALGSVGYSLSLFFVLFRAPDLALTQLCVETVSVALFL
                     LCFYHLPEFKKKEKKLHFKLTNLLISLGVGTIVTLIALSANSQRVSETISTYFIENSYK
                     LAGGKNMVNVILVDFRGFDTLFEIAVLGIAALGIFGMIRLKVRREEKG"
     gene            3364..3786
                     /locus_tag="MVE64_RS08525"
                     /old_locus_tag="MVE64_08525"
     CDS             3364..3786
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013085301.1"
                     /locus_tag="MVE64_RS08525"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MVE64_08525"
                     /product="Na(+)/H(+) antiporter subunit B"
                     /protein_id="WP_247347005.1"
                     /transl_table=11
                     /translation="MKTNDIIFQTVTKIVVFIIIIYSLHLFFSGHYTPGGGFIGGLMTA
                     SALVLLLLAFDIKTVVNTLQVDYLKLTATGLLIAVLTGIGSFFFNVPFLTHTFSYVQLP
                     LLGKTSLATAVLFDLGVYLVVIGVTMTIIQTIGETE"
     gene            3786..4127
                     /locus_tag="MVE64_RS08530"
                     /old_locus_tag="MVE64_08530"
     CDS             3786..4127
                     /GO_function="GO:0008324 - monoatomic cation transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_process="GO:0006812 - monoatomic cation transport
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391040.2"
                     /locus_tag="MVE64_RS08530"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MVE64_08530"
                     /product="Na(+)/H(+) antiporter subunit C"
                     /protein_id="WP_098795579.1"
                     /transl_table=11
                     /translation="MEILMSIVVGIIITAAVYLMLSKSLLRIIIGTGLLSHGAHLLILT
                     MGGLKKGAAPLLGEHAEVYVDPLPQALILTAIVISFGVTSFFLVLAYRSYQELGTDDMD
                     QLRGNDQYE"
     gene            4120..5598
                     /locus_tag="MVE64_RS08535"
                     /old_locus_tag="MVE64_08535"
     CDS             4120..5598
                     /GO_function="GO:0008137 - NADH dehydrogenase (ubiquinone)
                     activity [Evidence IEA]"
                     /GO_function="GO:0015297 - antiporter activity [Evidence
                     IEA]"
                     /GO_process="GO:0042773 - ATP synthesis coupled electron
                     transport [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019715549.1"
                     /locus_tag="MVE64_RS08535"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MVE64_08535"
                     /product="Na+/H+ antiporter subunit D"
                     /protein_id="WP_247345526.1"
                     /transl_table=11
                     /translation="MNNLIILPIVIPFLMGILLIFFNKHITVQKWLSAVASFLSVIASI
                     VIVQTVHTNGIQTLEIGNWAPPYGIVLVADMYASLLVLTTSIIGFTSLLFAFSSVTSDR
                     EKFYFYPGVQFLLLGVTGAFLTGDIFNLFVFFEVMLMSSYLLIVLGSSKNQLRESIKYI
                     LVNVISSALFVIAVAYLYAVTGTLNMADLSVRIADMGQSGLLTVIAILFLVIFGLKGAI
                     FPLYFWLPASYQAPPAVVTALFGALLTKVGVYSITRVYSVIFYHEPSFTHQILAWLSAL
                     TIVFGVIGAIAYWDIKKIVIYNIITAVGVILFGIAANTPNSVEGSIYYLVHDMIVKGAL
                     FFLVGAIIAITGTSNLRKFSGLIASHPFLGWMFLIATLALAGIPPLSGFIGKLKIIQGG
                     FEAGEYTIAFVVLLSSLLVLYSVMKIFIHGFWGEPNKIPVNKEATKGLILPIVILLVLS
                     IAYGFGVESLSPYISQAADTLLDPSIYIQAVLKE"
     gene            5604..6080
                     /locus_tag="MVE64_RS08540"
                     /old_locus_tag="MVE64_08540"
     CDS             5604..6080
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003184840.1"
                     /locus_tag="MVE64_RS08540"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MVE64_08540"
                     /product="Na+/H+ antiporter subunit E"
                     /protein_id="WP_247345528.1"
                     /transl_table=11
                     /translation="MAFQILLNFILGFLWMFLSNDYSSLAFAKGYFFGILILFVLRRFF
                     QHRFYFYNVIAIIKLLYIFLVELVKSNISVLKVILSPKLNLRPGIFALETELEKEWEIT
                     ILSNLITLTPGTLVLEVSEDNKTLYIHAMDIDDVEQAKLDIKNTFEKAIKEVSR"
     gene            6080..6364
                     /locus_tag="MVE64_RS08545"
                     /old_locus_tag="MVE64_08545"
     CDS             6080..6364
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007408673.1"
                     /locus_tag="MVE64_RS08545"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MVE64_08545"
                     /product="Na(+)/H(+) antiporter subunit F1"
                     /protein_id="WP_121663279.1"
                     /transl_table=11
                     /translation="MFKLVMTISLIIVAISTLLYVYRLVKGPSTPDRVIALDAIGINLI
                     AITAIISVVLNTSAFVEVILLLGILAFIGTVAFSKYLEKGEIIENDRDQ"
     gene            6348..6706
                     /gene="mnhG"
                     /locus_tag="MVE64_RS08550"
                     /old_locus_tag="MVE64_08550"
                     /pseudo=""
     CDS             6348..6706
                     /GO_function="GO:0051139 - metal cation:proton antiporter
                     activity [Evidence IEA]"
                     /GO_process="GO:0098662 - inorganic cation transmembrane
                     transport [Evidence IEA]"
                     /GO_process="GO:1902600 - proton transmembrane transport
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="mnhG"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015736053.1"
                     /locus_tag="MVE64_RS08550"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /old_locus_tag="MVE64_08550"
                     /product="monovalent cation/H(+) antiporter subunit G"
                     /pseudo=""
                     /transl_table=11
                     /translation="MIEISKFIVGYLILQGSLLSLIAAIGVVRLPDPYTRNHAASKSAT
                     LGIISILLEIYLCIIYSLIIMQIPECF"
     gene            complement(6804..7196)
                     /locus_tag="MVE64_RS08555"
                     /old_locus_tag="MVE64_08555"
     CDS             complement(6804..7196)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1144: thioesterase superfamily protein"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002015864.1"
                     /locus_tag="MVE64_RS08555"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MVE64_08555"
                     /product="hotdog fold thioesterase"
                     /protein_id="WP_247345531.1"
                     /transl_table=11
                     /translation="MDFNVKNTLMETLGIEVTTVTPECVIATMPVDHRTHQPFGLLHGG
                     ASVALAETVASIGAYNLVDHETEICVGLEINANHIRGKKSGVVTAYAKPAHRGKTTMVW
                     EIKIVDEDEELICLSRCTMAILKKQK"
     misc_feature    7169..7184
                     /note="TFBS match to ColR, Phenol-responsive regulator,
                     confidence: medium, score: 22.93"
                     /tool="antismash"
     gene            complement(7654..9954)
                     /locus_tag="MVE64_RS08560"
                     /old_locus_tag="MVE64_08560"
     CDS             complement(7654..9954)
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0000155 - phosphorelay sensor kinase
                     activity [Evidence IEA]"
                     /GO_function="GO:0046983 - protein dimerization activity
                     [Evidence IEA]"
                     /GO_process="GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1048: sensor
                     histidine kinase"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006638894.1"
                     /locus_tag="MVE64_RS08560"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MVE64_08560"
                     /product="histidine kinase"
                     /protein_id="WP_247345534.1"
                     /transl_table=11
                     /translation="MRLTFNRMLQLLVILSIIFVLYIIILNYKYPYVGARIIETNNEEM
                     LISEIEPKTWAEKVGIHVGDKIVEINNKDPQLHNPAVSHGLLEQINSVKVLKTNGITKE
                     YIVPSTLFSNQVLFMIIIPLTVLALCLFSIYFINKSNKETNQRSAHLLILFLLIVAMAY
                     LSASGSSRGDLLSRYVNIALFTLVPVSYLHFIYQYFKELGKELFRFSYIIFGYMLVFIN
                     ILAELVHNFWGMTIISNKLLTLVSFLILLILTFSLKFSGLRKIRYSEQAYLVKILIVTN
                     VLAFTPFLLFYVIPYVIFQKYVFSPIFLSAFLLLIPFSLVYQFLVTKIYDIEFLLGRLK
                     YYSILAIIPTLIMVMIMFTLKESNPTFYSVQLFVYIYLAMVFIFYVKEVLDDRFRLKRF
                     SEKYNYQDSIFKYTQSIRKASNLEQVIAELKQVIVDVLHVSKAYFIELDKVKNITSVDP
                     LAKEPNYRSYLKEIKEASNEIGKIVEIDKGFVINIGVTDNKSYVLVCLSILNTPKLTRD
                     EVSWLKTLSFYTNVSLENFLKIDELMQHLQKVETETEGGKPDWLNKILFSIEEKQRSHL
                     AKEIHDSVLQDLVSLKRQCELAMSEEDADVLKKQLQSINSSMTKVIKETRETCQELRPQ
                     LLYDLGLVKALNKLIMQYQDIVSFDIRLNTGNINASLDLDTQLNIYRIVQELLINAHKH
                     SEATNVVIILVFIKDKIVLHYEDDGIGFNYEEIGDQKERTGLSGISERVKALKGSFLIE
                     TSRENGLKIDIEI"
     gene            complement(10001..10915)
                     /locus_tag="MVE64_RS08565"
                     /old_locus_tag="MVE64_08565"
     CDS             complement(10001..10915)
                     /EC_number="2.5.1.-"
                     /GO_function="GO:0004659 - prenyltransferase activity
                     [Evidence IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /GO_process="GO:0008299 - isoprenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene-precursor: PT_FPPS_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1182: Polyprenyl synthetase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF012568.4"
                     /locus_tag="MVE64_RS08565"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MVE64_08565"
                     /product="polyprenyl synthetase family protein"
                     /protein_id="WP_247345536.1"
                     /sec_met_domain="PT_FPPS_like (E-value: 7.3e-20, bitscore:
                     69.4, seeds: 145, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MVDNEHIKQQMIQIIESQVKESELQHLVVSFIKEKDNFHFAHLAI
                     LHYDAFEGKNAEIVRLAAAIQLLILSFDMLDDLEDLDNMEEPWMKINSSIALNAATLIY
                     TLSHKVILSLSSPYKIQILDSFTRFSLQAMEGQHLDLENSLFSEDECIKMMKYKSGSLI
                     ALASVSGMLLAGANEEKVEAYSYQIGIAAQIENDFRDLFNPNKNDISAQKKSLGFLYLQ
                     KKCNEHALEIIEGFKSEKTVEAYFGSYKKFSNKLLNSGTVHYLNVMKQIAVNKAAKLIN
                     ELPIKQDQIERLKAVLLSSKEQF"
     gene            complement(11056..11196)
                     /locus_tag="MVE64_RS08570"
                     /old_locus_tag="MVE64_08570"
     CDS             complement(11056..11196)
                     /GO_process="GO:1900192 - positive regulation of
                     single-species biofilm formation [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016886113.1"
                     /locus_tag="MVE64_RS08570"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MVE64_08570"
                     /product="DegQ family regulator"
                     /protein_id="WP_098795571.1"
                     /transl_table=11
                     /translation="MNQQKIDEMTQLLLKIEQELKESKESLQLINKSIDKYDKFAFLNV
                     S"
     gene            complement(11588..11812)
                     /locus_tag="MVE64_RS08575"
                     /old_locus_tag="MVE64_08575"
     CDS             complement(11588..11812)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="MVE64_RS08575"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="MVE64_08575"
                     /product="hypothetical protein"
                     /protein_id="WP_247345539.1"
                     /transl_table=11
                     /translation="MMVQPTFYVLDDKMVAVFSVLKDNCKVTMECLYSKTGIEDYTIEY
                     HGPQEMKSQLIQLAVSEAENIFTKTILTV"
     gene            complement(12007..13227)
                     /locus_tag="MVE64_RS08580"
                     /old_locus_tag="MVE64_08580"
     CDS             complement(12007..13227)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391052.1"
                     /locus_tag="MVE64_RS08580"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MVE64_08580"
                     /product="HDOD domain-containing protein"
                     /protein_id="WP_247345541.1"
                     /transl_table=11
                     /translation="MEVFVARQPIFNIKEEVFAYELLYRGSKENIFPDIDGDLATTEVI
                     INSFLNIGIHDLSEGKRCFVNFTDSLLKSRVPTFFNPSSIVVEILENVEISEELILSCK
                     ELKELGYTIALDDFYVQEQSSLLPRLLPYVDIIKVDFLHTSKSEQKDMVERYRPHNIEL
                     LAEKVETRDDFLFAKKTGYTYFQGYFFSKPHIVSSYDVPSYLKTYYHILSEIAKTEPNI
                     DKIASEIEHDISMSYKLLKLINSPAFRPVNKIESIKQAIVLLGLNELKKWIYVISLKNI
                     NYPKDINMQEVIKLSLVRGKLCEQIAIYLGMGQSAPFMLTGMFSLIDTLMHRNIQDVLK
                     DLPLSDDIQDALLGKENDLYHVLLWAESIEKSTWDIEDLKIPKEEINRIYLSSIEWATN
                     LMELDEK"
     gene            13704..15146
                     /gene="hpaB"
                     /locus_tag="MVE64_RS08585"
                     /old_locus_tag="MVE64_08585"
     CDS             13704..15146
                     /EC_number="1.14.14.9"
                     /codon_start=1
                     /gene="hpaB"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007084455.1"
                     /locus_tag="MVE64_RS08585"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MVE64_08585"
                     /product="4-hydroxyphenylacetate 3-monooxygenase, oxygenase
                     component"
                     /protein_id="WP_247345543.1"
                     /transl_table=11
                     /translation="MPAINGEKYLERMDQLHPDVWMKGEKISGKLSQHPVYKGAMQSKA
                     SLYDTQVHPDFIKKMTFTSPTSNERVGLSFLQPRTKEDLEARRYMIKTWAKKTAGMMGR
                     TPDYLNTALMTFAASATILREQGDEFCKNLLNIYEDAREKDLSFTHSFINPQVNRSTNY
                     HELSSQPIAAKIIKKTSDGLILKGARMLATQGGMTDEVFILPTGQTDDYAFCFSIPTDA
                     DGIKFICRESFYQDDSQFNYPLSSRFDEMDTMIVFNNVVVPWERVIFYHRNDLAHQLFA
                     RSSFTPQALHQVIIRQITKTEFLIGLAQKMVTVLNVTEYHHIQEKISEMIIGLETMKAL
                     LDRSELEAKEDEWGTMVPYVHSLFVASNIFPKLYPRMIEIIQLIGAGGMVAIPSEEDFA
                     SSLVSEIDHFCQGYACDAETKAKLFRLAWDLTMSSFGTRQTQYERYFFGDPKRLTSTLY
                     QGYPREEYIRDVESFLEQNREA"
     gene            complement(15160..15408)
                     /locus_tag="MVE64_RS08590"
                     /old_locus_tag="MVE64_08590"
     CDS             complement(15160..15408)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019259338.1"
                     /locus_tag="MVE64_RS08590"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MVE64_08590"
                     /product="YueH family protein"
                     /protein_id="WP_247345545.1"
                     /transl_table=11
                     /translation="MKIRKANVKNGEEFITNVYIYENKKQEFSMIAIPEIEWSTTVSYE
                     EGREELRVRLQSSLSKRVEADTAGELAGKIGHWVGEM"
     gene            complement(15555..15776)
                     /locus_tag="MVE64_RS08595"
                     /old_locus_tag="MVE64_08595"
     CDS             complement(15555..15776)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003211468.1"
                     /locus_tag="MVE64_RS08595"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MVE64_08595"
                     /product="spore germination protein"
                     /protein_id="WP_247345548.1"
                     /transl_table=11
                     /translation="MPALVGPIKLNRIGDAAVFKVGDTFSLSPKSQNESSVGAGALNTG
                     DFIEIENVFTITNFEDSDIVDQPNTFNF"
     gene            complement(15859..16968)
                     /locus_tag="MVE64_RS08600"
                     /old_locus_tag="MVE64_08600"
     CDS             complement(15859..16968)
                     /GO_function="GO:0015562 - efflux transmembrane transporter
                     activity [Evidence IEA]"
                     /GO_process="GO:1905887 - autoinducer AI-2 transmembrane
                     transport [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003184877.1"
                     /locus_tag="MVE64_RS08600"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MVE64_08600"
                     /product="AI-2E family transporter"
                     /protein_id="WP_247345551.1"
                     /transl_table=11
                     /translation="MFRSKVHFWTLQILLMLLIVFVGTRVSFLFEPIIVFASTLFFPIL
                     IAGILFFIFNPLVKLLEKGKVPRTLAILIPYIVFIGVVSGIVSFIGPIVTEQITDLVNN
                     FPSYVNEFTQFIINMSQTHWFTWVMEQDYVSFKQIEDTLTGYAKSLPENITTSFTAVLG
                     VVTNITLTIITVPFILFYMLKDGHKLPSTAVKVLPSTYRHEGLKILQDLYETLAAYIQG
                     QLIVSIAVGIGCFIGYTIIGLDYALVLGIVVAVANIIPYLGPFIGAAPAVIIALLDSPT
                     KALLAALVVTIVQQLDGNFLSPLIIGKRLNTHPLTIILLLIGAGSFGGIIGMILAVPTY
                     AVLKAVVLNVIRLIKLRSKYKEELKNAKV"
     gene            complement(17219..18568)
                     /locus_tag="MVE64_RS08605"
                     /old_locus_tag="MVE64_08605"
     CDS             complement(17219..18568)
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1273: hypothetical
                     protein"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009795114.1"
                     /locus_tag="MVE64_RS08605"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MVE64_08605"
                     /product="hemolysin family protein"
                     /protein_id="WP_247345553.1"
                     /transl_table=11
                     /translation="MDIVNLIIVAILIAITAFFVASEFAIVKLRSSRIDQLIAEGNKSA
                     LAAKRVTSNLDEYLSACQLGITITALGLGWLGEPTMESILHPLLVSFNVNESIISVLTF
                     VIAFLVVTYLHVVIGELAPKTVAIQKAEFITLLFARPLIFFYRVMFPFIWILNGSANLL
                     VRMFGLKPASEHEIAHTEEELRIILSESYKSGEINQSEFKYVNRIFEFDDRIAKEIMVP
                     RTEIVTTSVEKSFQENLDIMRNEKFTRYPVVNGDKDHILGMVNIKEIFTDLYYLTPEGR
                     KNTFIQKYIRPVIQVIESIPIHDLLIKMQKERVHMAILMDEYGGTAGLVTVEDIIEEIV
                     GDIRDEFDQDEVPNIQKRGEKHFVVDGKVLIYEINNMLGLSIDDEDIDTLGGWILTQNM
                     ESKQGDKILYEGFEFHILDTEGHLIRSVEIKMASQHEIEEKTLQLLEAEE"
     gene            complement(18673..19356)
                     /locus_tag="MVE64_RS08610"
                     /old_locus_tag="MVE64_08610"
     CDS             complement(18673..19356)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003250270.1"
                     /locus_tag="MVE64_RS08610"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MVE64_08610"
                     /product="zinc metallopeptidase"
                     /protein_id="WP_247345554.1"
                     /transl_table=11
                     /translation="MFFHPMDFLIFAALGLSIWAQFKVKGNFKKWSDVAVSSHKTGAEV
                     ARHILDQNGLYQVKVEPVRGTLTDHYDPLSRVVRLSEPVYYGHSIASVSVAAHEVGHAI
                     QHQQSYGALVLRHKMFPVVNLTSGVAPFLLIGGFLLGQLNLIGLGIILFSFAVAFQLIT
                     LPVEFNASSRAKNLMVSEGIISNNEEHGVNKVLGAAALTYVAGALMALFELLKFVMIFV
                     QGDEE"
     gene            complement(19407..19832)
                     /locus_tag="MVE64_RS08615"
                     /old_locus_tag="MVE64_08615"
     CDS             complement(19407..19832)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1171:
                     transcriptional regulator, MerR family"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: protein motif:HMM:NF024803.4"
                     /locus_tag="MVE64_RS08615"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MVE64_08615"
                     /product="MerR family transcriptional regulator"
                     /protein_id="WP_247345557.1"
                     /transl_table=11
                     /translation="MLYKIGELAKEANVSKRTIDYYTQIGLLNVETISESKYRLYSEKA
                     IEDIRFIEACKELHMSLKDIKERLELKRLDKQCDEKQKQCLKHAEILASHMKQLEQEIK
                     ELKPIFDKLNEDSQMEISNQISSQSKALLKTLHLLLQ"
     misc_feature    19961..19973
                     /note="TFBS match to LuxO, Repressor of luminescence,
                     confidence: weak, score: 20.68"
                     /tool="antismash"
     gene            complement(20027..20245)
                     /locus_tag="MVE64_RS08620"
                     /old_locus_tag="MVE64_08620"
     CDS             complement(20027..20245)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003213721.1"
                     /locus_tag="MVE64_RS08620"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MVE64_08620"
                     /product="YuzF family protein"
                     /protein_id="WP_098795598.1"
                     /transl_table=11
                     /translation="MHSHGGPEMVTLVEPYVYQTLQTLVGKFAVIQTTRDSLRGKVMDV
                     KPDHVVVRVGDSTFFVRCQQIVSVMPD"
     misc_feature    20296..20310
                     /note="TFBS match to NrdR, Represses ribonucleotide
                     reductase encoding genes, confidence: weak, score: 19.4"
                     /tool="antismash"
     gene            complement(20334..20864)
                     /locus_tag="MVE64_RS08625"
                     /old_locus_tag="MVE64_08625"
     CDS             complement(20334..20864)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003184886.1"
                     /locus_tag="MVE64_RS08625"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MVE64_08625"
                     /product="HD domain-containing protein"
                     /protein_id="WP_247345559.1"
                     /transl_table=11
                     /translation="MRRVSITDVFTHPIAQKYLNRSGVSHAITVAQYAVQLAIKHDVNP
                     DIAAKAGLLHDIGHYEWYTNGEWDYEAYRKNDIHAIKGAERAHKLLIRLGEDRKYAKEV
                     ALAILLHTDSYLPENSIDKNTLQRIVRKADEMDEEPFGKHHYRKISYEDAIKQIERLDQ
                     EIEHFLTEYRKTV"
ORIGIN
        1 aaagaaatat tccgatgatt gcataaggat actgaacagc tgcaagagaa agtgccccac
       61 caattaaata aatggaagaa cctcctctaa ttttagtcaa attttcgcct gctacatctt
      121 ttgaaaaaaa caaaagcgaa agctcagtca ccgtgtttgc aattagcttt aatgctgaaa
      181 acagcataaa aaacagaaga gaaaaaacaa taaataacgc aagcttgatc ccactattag
      241 agaagaattc cagcattccg tcataaatac caaaaacctg caaaaaatcg attacaatca
      301 tgactgtaac gatcgataac gaagcactaa ataataagat tgtaatgaga ggaaaataac
      361 tagtaaagta tgtatttttc ataaaatcag tttccttgct aaataattca gtttccatcc
      421 tattatgaat tagcaaattc gctttgacaa gacttcatgt aaataaatag aaattcatct
      481 ttctatttac taaaaaacag gatgcctact aatccacacc ctgttaacga agtacaacgc
      541 gtacatattc acgcggtcga aacttttcaa aaacattcgc ttcctctgtt aacaattcaa
      601 tgggtgtttc agtatttgtt aattgaatgt ctgagtcttc aaatgcaatc gtttcgacat
      661 attctctttt tactctttca tttatatacc aagcactgct aaacaaggat gaaaacaaac
      721 accctgcgac aaaaatcttt gttttgtgca tggaatcacc tcaaacctta ggatgttctt
      781 aaggtcttta taatatacaa gtaggcagaa atttgttatc atttttatgt tcatatgaac
      841 ttgaaatgag caatatttga tataatttca tagtgctcca caatctggaa cataataaat
      901 cagtaatact gagccagatt tgttcttaat actataagga ggttaaaaga tgacattatt
      961 acatgtggca attttatcac catttttact tgccatactt attccattcc tgtataagta
     1021 ctttcgtaac attcatacag gctggtttgt actaggatta ccgatcctgc tctttgttta
     1081 ttttatacaa tttctagatt ctacgatgca tggtgatcaa atcagttaca ccgcaaattg
     1141 gataccttct cttggtatta actttactgc atacatagat ggtcttggac tgttatttgc
     1201 attattgatt tcaggaatcg gtgccctagt tgtcctatat tcgatctatt acctatcaaa
     1261 agagaaagaa caattaaaca ccttctatgt gtatttacta atgtttatgg gtgccatgct
     1321 cggtgttgtt ttatctgaca acctgatcgt cctatatacc ttttgggaat tcacatcact
     1381 ttcatctttc ttgttaatcg gttattggta tcaccgagaa aaatcacgtt acggtgcaca
     1441 gaagtctatg cttatcacta tatttggcgg acttctcatg cttggtggtt ttatcatgct
     1501 ctatatgatg actggtacct acagcattcg agaaattgtt ggtcaagttc cggaaatatc
     1561 acagcatgaa ctttttgtac ctgcccttat tttaattttg tttggagcct ttacaaaatc
     1621 agcgcagttt ccgttttata tttggttacc agacgcaatg gaagcaccaa caccagttag
     1681 tgcatatctc cactcagcaa ccatggttaa agctgggatt tatctagtag cacgcttcag
     1741 tcctgtattt tccgggacac ctgaatggtt ttggattgtt tcatcattcg gtattttcac
     1801 gatgttctgg ggatcattca atgcagtgaa gcagactgat ttaaaaggga tacttgcatt
     1861 ctcaacagtc agtcaattag gaatgattat gtcaatgctc ggtgttggtt ccgctgcact
     1921 agctctagag tctattgatg atagctacta tacagttgcg acgcttgctg ctattttcca
     1981 tctaataaac catgctactt ttaaaggaag cttgtttatg gtggttggaa ttattgacca
     2041 tgaaacagga acacgtgata tcaggaagct tggcggtctt atgagtttga tgccaattac
     2101 gttcacgata tcaattattg gagccttttc aatggcagga ttgcctcctt ttaatggttt
     2161 tcttagtaaa gagatgttct ttactagtat gatccgtgta atggaaatgg atgttttcaa
     2221 tattgaaaca attggtctat tattcccgat tatcgcctgg gttggtagta ttttcacctt
     2281 tatttacagc atggtattag tgtttaaaac cttcacaggg aaatatcaac ctgaaaagct
     2341 taagaagaag ccacatgaag caccaattgg aatgctcatt tcaccgatta tattggcttc
     2401 acttgtcgtt attttctttt tcttcccgaa cattttagct tatacaatta ttgaaccagc
     2461 gatggcttca atcattccgg gattactagg tgatgaagga cattttcatg ttcatatcta
     2521 tccttggcat gggtttactg ttgaattatt catgacaata ggtgttattg cattaggtat
     2581 tatcggatac ttatctctta caaaatggag atctgtttat cgtttagttc ctgaaaagct
     2641 aacgctaaat aaaggatatg atgctgcatt acatcaactt gatcgatcat cattccgttt
     2701 aactagattt tatatgactg gatttatccg tgattatctg gcgtatattt ttaccttctt
     2761 tattctgatt ctaggaactg cattggttgc aaccggagga tttacattct ccttggcagg
     2821 aactgctccg attggtgttt atgaggcagt tttagctttt gttatggtag ttggaacagt
     2881 gactgtttta ttttctaaat cccgtttgac tgccattatt gctctaggat cagttggata
     2941 ctcattatca ctctttttcg tcctatttcg ggcgcctgac ctagctttaa cgcaattatg
     3001 tgtggaaaca gtatcagtag ctttattcct actttgtttc taccatttac cggaatttaa
     3061 aaagaaagaa aaaaagcttc actttaaatt aacaaatctg cttatatctc taggtgttgg
     3121 tacgatcgtt acacttattg ctttatctgc caatagccaa cgtgtatctg aaacaatttc
     3181 aacttatttc attgaaaaca gctataagct ggcgggtgga aaaaatatgg ttaacgtcat
     3241 tcttgtagac tttagaggct ttgatacatt atttgaaata gctgttttag ggattgctgc
     3301 actaggaatt tttggtatga ttcgcttaaa agtcagaagg gaggaaaaag ggtgaaaaaa
     3361 gatataaaaa caaatgatat catctttcaa actgttacta agattgttgt gtttattatc
     3421 attatctatt cattacacct tttcttttct ggacactata caccaggtgg aggttttatt
     3481 ggcggactaa tgactgcttc ggcactcgtc ttactgttat tagcctttga tataaaaaca
     3541 gttgtcaata ccctacaggt tgattatctg aagttaacgg caactggttt attaattgct
     3601 gtattaacag gaatcggttc atttttcttc aatgtaccgt tcctaacaca tacatttagc
     3661 tatgtacagt tacctctgct agggaaaaca tccttagcta cagcggtatt atttgattta
     3721 ggggtttacc tcgttgttat cggtgtaacg atgaccatta ttcaaacgat tggagagacg
     3781 gaataatgga gattttaatg tctattgttg tcgggatcat tattacggct gcggtttatt
     3841 taatgttatc caaaagttta ttacgaatta tcattggtac tggtttgcta agtcatggtg
     3901 cacatttact catcttaacg atgggaggac taaaaaaagg tgctgctcca ttgcttggtg
     3961 agcatgcaga agtctacgtt gatccacttc cacaagcttt aattttaact gcaattgtta
     4021 ttagctttgg agtcacatcc tttttccttg ttcttgccta ccgttcatac caagagcttg
     4081 ggactgatga tatggatcaa ctaaggggaa atgatcaata tgaataactt aattatcttg
     4141 ccaattgtta tcccattttt aatgggaata ctcttaatct ttttcaacaa acatattact
     4201 gttcaaaaat ggctaagtgc tgttgcttca ttcttaagtg ttattgcttc cattgtgatc
     4261 gttcagactg ttcatacaaa cggcattcag acactggaga tcggaaattg ggcaccacct
     4321 tatggaatcg tacttgttgc cgatatgtat gctagcttgt tagtgttaac aacaagtata
     4381 atcggcttta catcgttatt gtttgctttc tcatccgtaa catcagatcg ggaaaagttt
     4441 tacttttatc caggagttca atttttactt ttaggtgtaa ctggagcttt tctaacaggt
     4501 gatattttta atctctttgt attttttgaa gtcatgctta tgtcttctta cttgttgatt
     4561 gtattaggaa gctccaaaaa tcagcttcgc gagtcaatta aatacatctt agtcaatgtt
     4621 atttcttctg cactttttgt cattgcggta gcgtatctat atgcagtaac aggaacatta
     4681 aatatggcag acttaagtgt aagaatagca gatatggggc aatccgggtt attaacagtc
     4741 atcgccatcc tctttctagt catctttggc ttgaagggtg cgattttccc gttgtacttt
     4801 tggcttcctg cctcctacca ggcaccacct gctgttgtta cagcattgtt cggcgcttta
     4861 ttaacaaaag ttggggttta ttccattacg cgtgtgtatt ccgttatttt ctatcacgag
     4921 ccatctttta cacaccaaat actcgcttgg ctttcagcac taacaattgt ttttggtgtt
     4981 attggagcaa ttgcctattg ggatattaaa aagattgtca tctataacat tattactgca
     5041 gttggtgtta ttttatttgg aatcgcagca aacactccaa attcagtaga aggctctatt
     5101 tattatttag ttcatgacat gattgttaaa ggagcattat tcttcttagt tggtgcaatt
     5161 attgcgataa caggcactag taatttacgt aaatttagcg gattgattgc tagccaccca
     5221 tttcttggat ggatgttctt aattgccact ttagctttag caggaattcc accacttagc
     5281 ggctttatcg gaaagctgaa aattattcag ggcggctttg aagctggtga atacacaatt
     5341 gctttcgttg tactgctttc aagtttgtta gtactatact ctgtaatgaa gatattcatc
     5401 catggttttt ggggagagcc aaataaaatc cctgttaata aagaggctac aaaggggtta
     5461 atactcccaa tagtcatctt gcttgtattg tcaattgctt atggttttgg ggttgaatca
     5521 ctatcacctt atatatcaca ggctgccgat actctgcttg atccatcaat ctatattcaa
     5581 gccgtattga aggagtagat catatggcat ttcaaatttt acttaacttt attttagggt
     5641 tcttatggat gtttctttcg aatgattatt cttccttagc ttttgctaaa ggatactttt
     5701 tcgggatatt aattcttttt gttctaagac gcttttttca acacagattt tatttttata
     5761 acgtgattgc gattattaag cttctctata ttttcttagt agagcttgtt aaatccaata
     5821 tctctgtatt aaaagtcatt ctatctccca agcttaattt aagacctgga atttttgctc
     5881 ttgaaacaga gctcgaaaaa gagtgggaaa ttacgattct atccaatctc attacattaa
     5941 caccgggaac tctcgtactt gaagtttctg aagataataa aacattatat attcatgcaa
     6001 tggatattga tgacgtcgaa caagcaaaac ttgatataaa aaatacattt gaaaaagcaa
     6061 tcaaggaggt gagccgttaa tgtttaagtt agtcatgacc atttcactca ttatagtagc
     6121 aatctcgacg cttttatatg tctatcgact tgtaaaagga ccatcaacac ctgatcgtgt
     6181 tattgcacta gatgcaatcg gtataaactt aattgcaata acggcgatta tctccgttgt
     6241 actaaataca agtgcatttg ttgaggttat tcttttatta ggaatattag cttttattgg
     6301 tactgttgcc ttttctaaat acctggagaa aggagagatc attgaaaatg atcgagatca
     6361 gtaaatttat tgttggctat cttattctcc aaggttcgtt actaagctta attgcagcaa
     6421 ttggtgttgt tcggttgcca gatccatata cacgtaacca tgcagcatca aagagtgcca
     6481 ctttaggaat cattagtata ctgctcgaaa tttatttatg tattatttac tcattgatca
     6541 tcatgcaaat tccagagtgc ttttagggat tatctttgtc tttatcacag cgcctgttgc
     6601 aggacatcta ataagtaggg cagcatataa tattggtgtt ccattgtggg agaaaagtgt
     6661 tcaagatgat ttagctaaag caagaaaaca tgaaaaaagt agatgagcgt tgctcatcta
     6721 cttttttata ctctaattaa ctgataccct cttgctttgc gcattcatga tcaaagcata
     6781 tcattcttta ataaaagatt tcctcatttt tgtttcttca aaattgccat tgtacatctg
     6841 gacaagcata tcagctcttc atcttcatct acgatcttta tttcccatac cattgttgtt
     6901 ttcccacgat gtgcaggttt agcatatgct gtgactacac ctgatttttt cccacgaata
     6961 tgatttgcgt ttatctctag acctacacat atttctgttt catgatcaac tagattgtaa
     7021 gcgccaatac ttgctacagt ttctgcaaga gcaactgatg ctccaccatg aagtaatccg
     7081 aatggttggt gtgtacgatg atctactggc attgtggcaa tcacacattc aggtgtaaca
     7141 gtggttactt ctattcctaa agtctccatt aatgtatttt tcacattaaa atccattatg
     7201 acccgaccct tcacatagtc tattactctt aataatttac cttgtttact ataaacaatt
     7261 gtaaatatag tctatcataa ggagattctt gaagcgaaaa ataatagatc aaaacatcac
     7321 ttaatggctt taaagaattt aagtgtgaat atttacagaa gtcgaagatg aaataaactt
     7381 caggcttaga tgatagctaa aatccttact atttccttag aacaaacaca acaaaaataa
     7441 aataaacaaa caataaaagt aatgttggaa gtacagccat aatatccatt ataacctcct
     7501 catttaggaa acgctttcct gattcctaaa aggatataat taacatctta atggataaat
     7561 atcatggcta tattgaggat ttgtttagtt tttgtaaaat taaagaaaac aggaaatgta
     7621 cttgaaatag aatagacctg gcattcacca agtctatatt tcaatatcta tttttaatcc
     7681 attttctctt gatgtttcaa ttaagaacga tccttttaaa gctttgaccc gttcacttat
     7741 accagaaagg cctgttcttt ctttttgatc acctatttct tcataattaa aaccaatacc
     7801 atcgtcctcg taatggagaa caatcttatc ttttataaaa acaagaataa tcacaacatt
     7861 tgttgcttct gaatgtttat gagcatttat aagcaattcc tgtacaattc gataaatgtt
     7921 taattgagta tcaagatcca aagaagcatt tatatttcca gtattaagtc ggatgtcaaa
     7981 gcttacaatg tcttgatatt gcataatgag cttatttaat gccttaacta agcctaaatc
     8041 ataaagtaac tgtggtcgca gttcttgaca tgtttctctt gtttctttaa taaccttcgt
     8101 catactgctg tttatgcttt gcagctgttt tttaagaaca tcagcatctt cttctgacat
     8161 tgccaattca cattgccttt ttaaagaaac caagtcttga agaacagagt catgtatttc
     8221 cttagctaaa tgagatcgtt gcttttcttc tatagaaaac aaaatcttat tcagccaatc
     8281 tggttttcct ccctctgtct ctgtctcaac cttttgtaag tgttgcatta gttcatcaat
     8341 tttcaaaaag ttttctaatg aaacatttgt gtaaaacgaa agagttttta accatgacac
     8401 ctcatcacga gttaatttag gtgtgtttag tatagacaag catactaata catagctctt
     8461 gttgtcagtt acacctatat taataacaaa acctttatct atttcaacaa tcttaccaat
     8521 ttcatttgaa gcttctttaa tttcttttaa ataagatcta taatttggtt cctttgctaa
     8581 gggatcaaca gaagtaatat tctttacctt atcaagctcg ataaaatatg ccttgctaac
     8641 atggagtaca tccacaatta cttgctttaa ttctgcaata acctgttcca aattacttgc
     8701 ttttcgtatg ctttgagtat acttaaaaat gctgtcctga taattatact tttcggaaaa
     8761 ccgctttaat ctaaaacgat catctaaaac ttccttcaca taaaaaatga acaccatagc
     8821 taagtaaata taaacaaaaa gttgaacaga ataaaaagtt ggattgcttt cttttaaagt
     8881 gaacataatc ataaccataa tcagagttgg aattatggca agtattgaat aatatttaag
     8941 tcttcctaac aagaattcta tatcgtatat cttcgttacc aaaaattgat aaactaatga
     9001 aaagggaatt aagagtaaaa aagcagataa aaatattggc gaaaatacat acttttgaaa
     9061 aattacatac ggaatgacat agaacaaaag aaaaggtgta aaagctaaaa catttgttac
     9121 aattaatatt ttgactaaat atgcttgttc tgaatatcta atctttctta aacctgaaaa
     9181 ctttaaacta aaagttaaaa taagtaaaat aagaaatgac actagtgtaa gcaacttgtt
     9241 acttattatg gtcattcccc aaaaattatg aactaattca gccaaaatat tgataaatac
     9301 gagcatataa ccaaatataa tataagaaaa tctgaaaagt tcttttccta attctttaaa
     9361 atattgatag ataaagtgta aatagcttac tggaactaat gtaaataagg ctatattcac
     9421 gtatctactt agtaaatctc cccttgaaga accacttgca ctaagataag ccatggctac
     9481 tattaataaa aatagtatta ataaatgagc agaccgttga tttgtctctt tgtttgattt
     9541 attaataaaa taaatactaa acaagcataa ggcaagaact gttaaaggga tgattatcat
     9601 aaacaaaacc tgattactga ataaagttga tggaacaata tattctttag ttattccatt
     9661 tgttttaagt accttaactg agtttatctg ttcaaggaga ccatgactaa cagctggatt
     9721 atgaagctgt ggatctttgt tatttatttc aacgatctta tccccaacat gaatacccac
     9781 tttttctgcc caggtttttg gctcaatttc agaaatcagc atttcttcgt tatttgtttc
     9841 aattattcta gctccaacat atgggtattt ataatttaaa attataatat aaagaacaaa
     9901 aataatactt aatatgacta atagttggag catcctatta aaggtaagac gcatctaaat
     9961 tataatcacc tttcaacata aattatgata ttaatatcgt tcaaaattgt tctttactac
    10021 ttaatagaac agcttttaat ctctcaattt ggtcttgttt aattggtaat tcatttatta
    10081 attttgctgc tttatttaca gctatttgct tcatgacatt taaataatgc acagttccgg
    10141 aatttaagag tttgttacta aattttttat aactcccaaa gtaggcttcg actgtttttt
    10201 cacttttaaa gccttcaata atctccaaag catgttcatt acactttttt tgaaggtaaa
    10261 gaaagcctaa tgattttttt tgtgctgaaa tgtcgttttt atttggatta aataaatctc
    10321 taaagtcatt ttcaatttgt gcagcaattc caatttgata cgaatatgcc tcaacttttt
    10381 cttcatttgc accagctaaa agcatgccac ttacagatgc taatgcaatt aaagaacctg
    10441 acttatactt catcattttg atacattcat cttcactaaa taaagagttt tccaaatcaa
    10501 gatgctgccc ttccattgct tggagagaaa acctagtaaa tgaatcaagt atttgaattt
    10561 tatatggaga agataatgat aatatcactt tatgacttaa cgtataaatc aacgttgccg
    10621 catttaaagc aatagaagag ttaattttca tccaaggctc ttccatatta tctaagtctt
    10681 caagatcatc caacatatca aaagataaga ttaataattg aatagcagca gccagcctca
    10741 ctatttctgc attctttccc tcgaatgcat cataatgtaa tatggccaaa tgagcaaaat
    10801 gaaagttgtc tttttcctta ataaaagaaa caacaagatg ctgtaattcg ctctctttta
    10861 cttgcgattc aatgatttga atcatttgtt gtttaatatg ttcattatca accatctttt
    10921 ggccaaccac ctgtctagct ttatatgact acatgctgag atctctttcc gaataaatca
    10981 atcatcttcc attctcaact aaccgccaaa ttatgtcaat aaaaaacaaa agaaacttgg
    11041 ttttatccaa gtttcttaag atacatttaa aaatgcaaat ttatcatatt tatcgatact
    11101 tttatttata agctgcagcg attcttttga ttcttttaac tcttgttcta tctttaataa
    11161 aagctgtgtc atttcatcaa tcttttgttg attcacagtt tcacactccc tatttgttgg
    11221 taagcgaatg taaggccaac ctagtctgct ttctataagt taaattctaa tctaaataag
    11281 gtattttttc accgaaaata attcttatga ctcaatgcgt gatgccgcaa gtcaaacgca
    11341 atagttcaaa ttatatattt cttcgtctta ccgacttttt ttatttttgt ttctacctta
    11401 agtcctaaca aataaacatt tcgtctgtca ttttgttttt atgggtatat ggtaagcctc
    11461 tattttcata ttttgagcaa aaatagtcca ttccattgcg ctccattatc ggtaattaaa
    11521 aaaccagatg aaaagttttt ttaacagcct aaaaaagaga cctatttcaa atagatctct
    11581 acctaactta aacagtcaat atagtctttg taaaaatgtt ttctgcctct gaaacagcta
    11641 gttgaattaa ctgagatttc atttcttgag gaccatgata ctctatcgtg taatcctcaa
    11701 ttcctgtttt tgaatacaaa cactccattg tcaccttgca attgtccttt aacaccgaaa
    11761 aaaccgcaac catcttgtca tctaacacat aaaatgttgg ctgcaccatc atcgtgtcta
    11821 caagcctcct tagaataaag agaattttga ggacttgtca taggatgtgt acactcttat
    11881 ctttaacatt ctctgtttga tgacagtttc cttcaactat ttacaaatta ttattgaaca
    11941 tcgaaaaaaa taaagtgcag gtaaagtacc cacactcgtt cccgtaataa taaatgttta
    12001 attctcctac ttttcatcta attccataag gtttgttgcc cattcaatag aagataaata
    12061 aatgcggtta atctcttctt ttggtatttt caaatcttct atatcccaag ttgatttttc
    12121 aatactttcg gcccaaagta acacgtgata taaatcgttt tctttcccga gcaaagcatc
    12181 ttgaatatca tcggataatg gtaggtcctt taacacatcc tggatatttc gatgcatcaa
    12241 tgtatcaatt aatgaaaaca ttcctgttaa catgaaaggt gctgactgac ccatccctag
    12301 ataaatggca atctgttcac ataacttccc acgaactaag gataacttaa ttacttcttg
    12361 catattaata tcttttgggt aatttatatt ttttaatgaa ataacataaa tccatttttt
    12421 aagttcattt aatccaagta ggacaattgc ctgtttgata gattcaattt tattaacagg
    12481 tctaaaagcc ggtgaattaa ttaattttaa cagcttatat gacatagaga tatcatgctc
    12541 aatttcggag gcaattttat caatattggg ttctgtcttc gctatttctg aaagtatatg
    12601 ataatacgtt tttagataag aaggaacatc ataacttgaa acaatatgtg gtttgctaaa
    12661 aaaataaccc tgaaaatatg tatatcccgt tttctttgca aataaaaaat catctcttgt
    12721 ttccactttt tctgctaaaa gttctatatt atgaggacga taccgttcaa ccatgtcttt
    12781 ttgttcactt ttggatgtat gtagaaagtc cactttaatg atatcaacat aaggtaataa
    12841 tctcggtaat aaggatgatt gctcttggac ataaaaatca tcaagcgcaa ttgtataacc
    12901 taattctttt aactctttac atgaaagaat cagttcttca cttatttcaa cattctctaa
    12961 tatttctaca acaatagatg agggattaaa aaatgttggt actcgggatt ttagcagact
    13021 atctgtaaag ttgacaaaac aacgtttgcc ttctgataaa tcatgaatac caatatttaa
    13081 aaaactatta ataatgactt ctgttgtagc aaggtctcca tcaatatctg gaaatatatt
    13141 ttccttactt cctctatata aaagttcata tgcaaaaact tcttctttta tattaaatat
    13201 tggctgccgt gcaacaaaaa cctccatgct ttgacccccg atacaaaaaa taaccaataa
    13261 tttcaattta ttctatttta ctacatttat cttaataata aatcatattt tggttattta
    13321 ctaacaattg tgggtccata gtattataaa tgactcaaaa aactcagcgt tattttcatc
    13381 catccgaaaa atgataacca taatggtaca ctcagcaatg tggcccaagc cattccttta
    13441 aaaaaatttt cttcatgcat agtgttcaca ccccttataa agatctgtag tcattatttt
    13501 ttccatggta ttatttatta aacataaagt aagcgcttac agtcagattt ttcttattac
    13561 tacttacaat attcatccat agacagcatc attcctctct atatcattct tctttttcca
    13621 acatcgtttt catcctatgt atcttctcac ctcactaccc atcctttcat atagtaatga
    13681 catataggta gggagtgaaa ataatgcctg caattaatgg tgaaaaatat ttagagcgca
    13741 tggatcagct acatcctgat gtatggatga agggggaaaa aatttcaggg aagctctcac
    13801 agcacccagt ctataaaggt gccatgcaat caaaggcatc tctgtatgac actcaagttc
    13861 atcctgattt cataaaaaaa atgaccttta catctcctac atcaaatgaa cgtgtaggac
    13921 tatctttttt gcaacccaga acgaaagaag acctagaagc aagaagatat atgattaaaa
    13981 cttgggccaa aaaaacagca ggaatgatgg gacgtacacc agattactta aacacagcat
    14041 taatgacgtt cgctgcttca gctactattc tacgtgaaca aggtgatgag ttttgtaaaa
    14101 atctactgaa tatttatgag gatgccagag aaaaagatct ttccttcaca cacagtttta
    14161 tcaatccaca agtaaatcgt tcaacaaatt atcatgagtt atcttcacaa ccaattgctg
    14221 caaaaataat aaagaaaaca tcagatggac ttatactaaa aggggcaagg atgttagcaa
    14281 cacaaggagg tatgactgat gaggtattca tcttacctac aggtcaaacc gatgattatg
    14341 ccttttgttt tagtattcct acagatgcag atggaattaa atttatctgc cgtgaatcct
    14401 tttatcaaga cgactctcaa tttaactatc cactttcttc tcgtttcgat gaaatggaca
    14461 cgatgattgt ctttaataat gtagtagtgc cttgggaaag agttattttt tatcaccgta
    14521 atgatcttgc acatcagctt tttgcaagaa gtagctttac accacaagca ttgcaccagg
    14581 tcattattag acaaattaca aaaacagagt tcttaattgg tcttgcacaa aaaatggtta
    14641 ctgttttaaa cgtaacagag tatcatcata tacaagaaaa aattagtgaa atgattattg
    14701 ggttagaaac aatgaaggct cttttagatc gttcagagct tgaagcaaag gaagacgaat
    14761 gggggacaat ggttccatat gttcactctt tatttgttgc atcaaatatt ttcccaaagc
    14821 tttaccctcg aatgattgaa atcattcaat taataggtgc cgggggaatg gtagctatac
    14881 cttcagaaga ggattttgct tccagcttag ttagtgaaat tgatcatttc tgtcaaggat
    14941 atgcatgtga tgctgaaaca aaagcgaagc tctttcgcct tgcatgggat cttacgatga
    15001 gcagctttgg aacacgacaa acacaatatg aacggtattt ttttggtgat cccaagaggc
    15061 taacatcaac tctttatcag gggtaccctc gtgaagaata cattcgtgat gttgaaagtt
    15121 ttttagagca aaatagagag gcttaacgac aaagcctctt tacatttccc ctacccaatg
    15181 tcctattttt cctgcgagct caccagcagt atcagcttcc actcttttcg ataaagatga
    15241 ttgaaggcga actctaagtt cttctcttcc ctcttcatag ctaacagtcg tagaccactc
    15301 aatttccggg atggcaatca tactgaattc ttgtttttta ttttcataaa tataaacgtt
    15361 tgttatgaat tcttctccat ttttcacatt tgcttttcta attttcacta ttcttcatcc
    15421 tttcagcagt ctctgccatt attataaatc atgtttcttt caatttcagc attcactacc
    15481 ccaaacaaca aacaaaagaa ctgatttagt aggaacctaa atcagttctt ttggatgata
    15541 actcttaaca caacttaaaa gttaaaagtg tttggttgat ccacaatatc actatcttca
    15601 aaatttgtga tcgtaaacac gttttcaatt tcgataaaat cgcctgtatt tagtgcccct
    15661 gcaccaacag atgactcatt ttgactttta ggtgacaaac taaacgtatc acccacttta
    15721 aaaacagctg catctcctat cctattaagc ttgataggtc caactaatgc cggcataccc
    15781 ttcctccctt atcacataca tgtaaagtta attgttcaac atcatatgaa aaagagaaaa
    15841 aagggttctc gcctaacttt atactttagc attctttagc tcttctttat atttagatct
    15901 taatttgatt aatcgaataa catttaaaac aacagctttt aacacggcat acgttggaac
    15961 agcaagaatc attccaatga ttcctccaaa gctaccagct cctattaaaa gtaaaataat
    16021 tgttaaagga tgtgtgttca aacgcttccc gataattaac ggagaaagga aattcccatc
    16081 aagctgttgt acaatcgtta ccactaaagc agcaagcaat gcttttgtcg gcgaatctaa
    16141 taaagcaata atgacggctg gagcagcacc gataaacggc cccaaataag gaattatatt
    16201 agctaccgcg acaacaattc cgagaacaag tgcataatca agtcctatta tagtataacc
    16261 tatgaagcat ccaatcccca cagcaatgga cactattaac tgtccttgta tgtaagctgc
    16321 taacgtttca tataaatctt gtaaaatctt caatccttca tgacgatatg ttgatggtaa
    16381 aacctttact gccgtagaag ggagcttatg accatctttt aacatgtaaa aaagaataaa
    16441 tggaactgta ataatcgtta aggtaatgtt tgttacaaca ccaagcacag ctgtgaagct
    16501 tgttgtaata ttttccggca ggctcttcgc ataaccagtc aatgtatctt ctatttgctt
    16561 aaatgacaca taatcctgct ccatgaccca tgtaaaccag tgagtttgag acatattaat
    16621 aataaattgt gtaaactcgt ttacgtatga agggaaatta ttcactaaat ctgttatttg
    16681 ttctgtaaca atcggtccaa taaatgaaac aatccctgaa acgacaccaa taaatacaat
    16741 atatggaatc aggatagcca gtgtacgagg aacctttcct ttttcaagta acttcactaa
    16801 tggattaaaa atgaagaata gaattcccgc aataagaatt gggaaaaaca aagttgatgc
    16861 aaaaacaata atgggttcaa acaaaaagga aacccttgtt cctacaaaaa caattaataa
    16921 cattaataaa atttgcaatg tccaaaaatg aacttttgat ctaaacactc tacttcctcc
    16981 agtttctata gacctcatct atttttcagt atagtcatct ataaccttcc ttaagcaact
    17041 taaacatttg tatctaacag tatatacgac tattcctcga aattgtttca aaataattca
    17101 aattttcata tactacaaat gtacatgatt tactagatct ttaccaatct tttctttacg
    17161 taaacagctt aacctaaaga aagccagccc tgttgtcgga ctgactttag tgttgaaatt
    17221 attcttcagc ttccaataat tgaagtgttt tttcttctat ttcatgctga gaagccattt
    17281 tgatttctac agaacgaatc aggtgacctt ccgtatctag aatatgaaac tcaaatcctt
    17341 catacagtat tttatctccc tgtttacttt ccatgttctg agtcagaatc catcctccaa
    17401 gagtatcaat atcttcatca tcaatactta agcctaacat attattaatt tcgtagatta
    17461 acacctttcc atcgacaaca aaatgttttt ctccacgctt ttgaatgtta ggaacctcat
    17521 cctgatcaaa ctcatcacgt atatctccaa caatttcttc aataatatct tcaaccgtca
    17581 caaggccagc tgttccacca tattcatcca ttaatatcgc catatgaact cgttcctttt
    17641 gcattttaat caaaagatcg tgaattggaa tcgattcaat cacttgtatg actggacgaa
    17701 tatatttttg aataaacgta ttttttcggc cttcaggtgt taaatagtat aaatcagtaa
    17761 agatttcttt aatatttacc attccaagaa tatgatcttt atccccgttt actacagggt
    17821 atcgagtaaa cttctcgttt ctcataatat caagattttc ctgaaaagac ttctctactg
    17881 atgttgttac gatttcagtt ctaggaacca taatttcctt tgcaattcga tcgtcaaact
    17941 caaatattct attcacatat ttaaactcag attgattgat ttcaccactc ttatagcttt
    18001 cagaaagaat aattctaagc tcttcttctg tatgagcaat ttcatgttct gatgctggct
    18061 taagtccaaa cattcgaaca agtaaatttg cagaaccatt taatatccaa ataaatggaa
    18121 acatgactcg gtagaaaaaa atcaaaggtc gtgcaaagag caatgtaata aattcagcct
    18181 tttgaatggc cactgttttt ggagccaatt cacctattac aacatgcaag taggtaacca
    18241 ctaaaaaggc aatgacgaat gttaatacac ttataattga ttcattcaca ttaaaactga
    18301 ctagaagagg gtgtagtata ctttccatcg ttggttcgcc aagccaccca agacccagag
    18361 cagttatcgt aatacctaat tgacaagcag acaaatactc atcaaggtta gatgttaccc
    18421 tctttgctgc aagtgctgac ttatttcctt ctgctataag ctggtcaatt cgtgaacttc
    18481 ttagtttcac aatcgcaaat tccgatgcca cgaaaaatgc ggtaattgca attaaaatcg
    18541 caacaataat caggttaact atatccaaaa taaggaactg tcctatcgtg ttactagtat
    18601 ctatcaaact aatacacttt tataaataga cagttccttt cacctcctaa attaagaaaa
    18661 tttaaacgaa tattattctt cgtcaccttg tacaaagatc ataacgaact ttagtaattc
    18721 aaataatgcc attaatgctc cagctacata tgttaatgca gcagcaccta acaccttatt
    18781 aacgccatgt tcttcattgt tagaaataat tccttccgaa accattaaat tctttgctct
    18841 cgagcttgcg ttaaactcta caggtaaagt gataagctga aacgctacag caaatgaaaa
    18901 caaaatgatt cctaaaccaa ttaagttaag ttgccctaac aagaatccgc ctattaataa
    18961 aaatggggca acaccagatg ttagatttac aactggaaac attttatgac gaagcactaa
    19021 agcaccgtat gattgctgat gctgaatggc atgcccaacc tcatgagcag caactgaaac
    19081 tgaagcaatg gaatgtccat aatataccgg ttctgataac cgaacaactc gagaaagtgg
    19141 atcatagtga tctgttaacg ttcctctaac cggctctacc ttaacttgat ataggccatt
    19201 ttgatctaaa atatgtctcg ctacctcagc acccgtttta tgtgatgaaa cagccacatc
    19261 tgaccacttc ttaaaattac cctttacttt aaattgagcc catattgata agcctaatgc
    19321 tgcaaaaatt aaaaaatcca ttgggtggaa aaacattcgt ttccgctcct ccttttcata
    19381 tctcaacgtt tttgtgcact tttaaactat tgtaatagca aatgcaatgt cttcagtaaa
    19441 gctttgcttt gtgatgagat ttgattagaa atctccattt gagaatcttc gtttagttta
    19501 tcaaaaattg gtttaagttc tttgatttct tgttccagtt gcttcatgtg agaagccaga
    19561 atttcagcat gttttaagca ctgcttttgc ttttcatcac attgtttatc cagccgctta
    19621 agctccaaac gttcctttat atcttttaaa ctcatgtgaa gttctttgca cgcttcgata
    19681 aaacggatat cctcaattgc cttttctgaa tataaacgat atttagattc agaaatggtt
    19741 tcaacattta aaagaccaat ttgagtataa taatcaatcg ttctttttga gacatttgct
    19801 tcctttgcta attcaccgat tttatacagc aaaaccccat cttatcacct cgtacaattg
    19861 atacaaatat cttatcctct ccaaaccgta cagtcaaacg ttatacttgt tattttaatc
    19921 tttatttata gagtgtattg gatatgtcat cttttttggt ttgcattatg taaatggtta
    19981 ttaatcatag aaaaaaacag acctgtttag gtctgctttt caatcatcag tcaggcataa
    20041 ctgacacgat ttgttgacat cttacaaaga atgttgaatc tcccactctt acgactacgt
    20101 ggtctggttt gacatccatt acttttcctc ttaagctgtc acgtgttgtt tggattacag
    20161 caaacttacc tacaagagtt tgcaatgttt gataaacata aggctcaaca agagtaacca
    20221 tttctgggcc accatgacta tgcatttgat tattaggata attcattata aaagctccct
    20281 cccttatttt catttacact atatgggggg agctaggcca atgtcacaaa catttaaact
    20341 gttttgcgat actctgtcaa aaaatgctca atttcttgat caagtcgttc tatttgtttt
    20401 atggcatctt cgtagctaat ttttctgtag tggtgcttgc caaaaggttc ctcatccatt
    20461 tcatccgctt ttcggacaat gcgttgtaat gtgtttttat ctattgagtt ttccggtaaa
    20521 taagaatctg tatgaagtaa aatagcaaga gcaacttctt tagcgtattt gcggtcttca
    20581 ccgagtctaa ttaaaagctt atgtgctcgt tctgctcctt taatggcatg aatgtcattt
    20641 tttcgatatg cttcataatc ccattctcca tttgtgtacc attcatagtg tccgatgtca
    20701 tgaagcaatc ctgccttagc tgctatgtcg ggatttacat catgcttaat ggcgagctgc
    20761 acagcatatt gggcaacagt aatcgcatgt gaaactccgg aacgattcaa atatttttgt
    20821 gctataggat gtgtaaaaac atcggtgata cttactcgtc gcatggaaat cctccttcaa
    20881 taatattcag aataatctaa cacatatatg ttatc
//
