LOCUS       NZ_CP095550            20897 bp    DNA     circular CON 11-MAY-2024
DEFINITION  Metabacillus endolithicus strain KCTC 33579 chromosome.
ACCESSION   NZ_CP095550
VERSION     NZ_CP095550.1
KEYWORDS    RefSeq.
SOURCE      Metabacillus endolithicus
  ORGANISM  Metabacillus endolithicus
            Bacteria; Bacillota; Bacilli; Bacillales; Bacillaceae; Metabacillus.
REFERENCE   1  (bases 1 to 5052055)
  AUTHORS   Lee,K. and Son,H.
  TITLE     Metabacillus endolithicus type strain genome analysis
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 5052055)
  AUTHORS   Lee,K. and Son,H.
  TITLE     Direct Submission
  JOURNAL   Submitted (11-APR-2022) Bio Health Science, Changwon National
            University, Changwondaero, Changwon, Gyeongnam 51140, South Korea
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: Miniasm v. 0.3
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 69.5x
            Sequencing Technology             :: Oxford Nanopore MinION
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_023078335.1-RS_2024_05_11
            Annotation Date                   :: 05/11/2024 05:30:11
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 5,521
            CDSs (total)                      :: 5,322
            Genes (coding)                    :: 4,799
            CDSs (with protein)               :: 4,799
            Genes (RNA)                       :: 199
            rRNAs                             :: 16, 15, 15 (5S, 16S, 23S)
            complete rRNAs                    :: 16, 15, 15 (5S, 16S, 23S)
            tRNAs                             :: 146
            ncRNAs                            :: 7
            Pseudo Genes (total)              :: 524
            CDSs (without protein)            :: 523
            Pseudo Genes (ambiguous residues) :: 0 of 524
            Pseudo Genes (frameshifted)       :: 474 of 524
            Pseudo Genes (incomplete)         :: 58 of 524
            Pseudo Genes (internal stop)      :: 17 of 524
            Pseudo Genes (multiple problems)  :: 23 of 524
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 08:11:14
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 13943
            Orig. end                         :: 34840
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP095550.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..20897
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene"
                     /region_number="1"
                     /rules="(PT_phytoene_like or phytoene_synt or Lycopene_cycl
                     or Lycopene_cycl_fung or T1TS or T1TS_KS or T2TS or TS_UbiA
                     or TS_Pyr4)"
                     /tool="antismash"
     cand_cluster    1..20897
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /kind="single"
                     /product="terpene"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..20897
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:10897](-)"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..10897)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
     gene            complement(837..1163)
                     /locus_tag="MVE64_RS00045"
                     /old_locus_tag="MVE64_00045"
     CDS             complement(837..1163)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013524056.1"
                     /locus_tag="MVE64_RS00045"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MVE64_00045"
                     /product="nucleoside triphosphate pyrophosphohydrolase"
                     /protein_id="WP_247342472.1"
                     /transl_table=11
                     /translation="MPVYNKLVRDRIPEIIEKTGKAYKTSILSHEVYIKKLQEKGFEEL
                     QEYVEANDKDSSLEELADLLEIVHALAEFHGSSISEVEKIRAKKAQERGGFKEKIYLIE
                     VEDE"
     gene            complement(1179..1541)
                     /locus_tag="MVE64_RS00050"
                     /old_locus_tag="MVE64_00050"
     CDS             complement(1179..1541)
                     /EC_number="2.1.1.-"
                     /GO_function="GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015593697.1"
                     /locus_tag="MVE64_RS00050"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MVE64_00050"
                     /product="HIT family protein"
                     /protein_id="WP_247342475.1"
                     /transl_table=11
                     /translation="MNCPFCSNIEPVLQNDLSIAFYDIYPVNKGHLLIIPKRHVEQYFD
                     LTIEERQAIDSLLFEGNALLDKKHKPDGYNIGINNGEVAGQTIFHVHVHLIPRYKGDMK
                     DPRGGVRGVIPDKRTY"
     misc_feature    complement(1862..1875)
                     /note="TFBS match to PsrA, Oleic acid responsive regulator,
                     confidence: medium, score: 21.24"
                     /tool="antismash"
     gene            complement(2073..2840)
                     /locus_tag="MVE64_RS00055"
                     /old_locus_tag="MVE64_00055"
     CDS             complement(2073..2840)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017378794.1"
                     /locus_tag="MVE64_RS00055"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MVE64_00055"
                     /product="DUF4230 domain-containing protein"
                     /protein_id="WP_247342476.1"
                     /transl_table=11
                     /translation="MNTSREIIEEKDEKIAQLERQIKELYEATQQIAATIAVDQNSRYV
                     SPPIGKSKSLLKIGRLKNILILAIVILVAFIIAFGVFRPFAGSTIKQESVTFVERVQEL
                     ATLATAEAHMKEVLHQEENKNFLNIDLPGTKREVLLVVPATVIAGVDLKGITSKDLDIN
                     EETKEIDITLPHAEIIQEPSVQMDKIQAVDKNGLFRDDIKMNEGFELAAEAQEKIRQGA
                     ISSGLLDSAEKNAEKVLKEFFKNDGYTVNVSFN"
     gene            complement(2997..3926)
                     /locus_tag="MVE64_RS00060"
                     /old_locus_tag="MVE64_00060"
     CDS             complement(2997..3926)
                     /EC_number="3.1.21.-"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0004519 - endonuclease activity [Evidence
                     IEA]"
                     /GO_process="GO:0009307 - DNA restriction-modification
                     system [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF016362.4"
                     /locus_tag="MVE64_RS00060"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MVE64_00060"
                     /product="restriction endonuclease"
                     /protein_id="WP_247342479.1"
                     /transl_table=11
                     /translation="MTRYFKYVSIRNGQEEWMIKELNEGRARFGWSSPGSNLHIIKSKE
                     AKERSTKEKVVWRYTQFLINRLKAGDRLIIQLGQPLRQFLIAEIVGEYGSTDPQEKDFN
                     HYVQCKLLTNSFIQVKSEAVSQSLRHHLSKRGHYYEIYDEDSKEELDLIVKKSMEEDES
                     FHKANQSLRSIDYERTALEESVVAQTYKRISKNWPSAYFEQFVADLINATPGLEVKKQG
                     DSGKGWDLTMRIMDPLDGFILHDDIPVQCKNYQGKVNTKRPLDDLERCIRNSDASLAYL
                     FIIGDLSSDFYDEVDERVEQLRNDLQKR"
     gene            4306..5043
                     /locus_tag="MVE64_RS00065"
                     /old_locus_tag="MVE64_00065"
     CDS             4306..5043
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017797651.1"
                     /locus_tag="MVE64_RS00065"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MVE64_00065"
                     /product="alpha/beta hydrolase"
                     /protein_id="WP_247342482.1"
                     /transl_table=11
                     /translation="MKSIIKKTAIIFSIFIIISLLGLWIWSQQTYKPSEQLFQLVEPTS
                     IIYKEDWIVFQPQNDPVAGLIIYPGAKVEPEAYSYLGKQLSLEGYVVFIPEFTFNFPIL
                     DSNKAQEIITHYPEIKHWFVGGHSLGGVSAAMFAQNHIKELTGLILLGSYPSNEDRFSS
                     VDFPILSIYGEKDGLTTVDKIKETEELLSTNAQLVEIQGGNHSQFGIYGFQKGDHKATI
                     SAKNQQQQIIDIISKWLGDTLNE"
     gene            complement(5209..6315)
                     /locus_tag="MVE64_RS00070"
                     /old_locus_tag="MVE64_00070"
     CDS             complement(5209..6315)
                     /EC_number="2.4.-.-"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Glycos_transf_2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1123: polyprenol-monophosphomannose synthase ppm1"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009792317.1"
                     /locus_tag="MVE64_RS00070"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MVE64_00070"
                     /product="glycosyltransferase"
                     /protein_id="WP_247342483.1"
                     /sec_met_domain="Glycos_transf_2 (E-value: 3.6e-26,
                     bitscore: 90.3, seeds: 256, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTVSEVINLAIGFAAVVVGVLMFWSLPVPGFTSRPTAGLPFLSII
                     IPARNEEGRISPLLQSLQEQRFRQFEILVVDDDSSDNTASVAESYGAKVLQNAGAGKSS
                     ACWQGAKQAKGSWLLFLDADTRFTSVDGLSNLLHFYQQKGAKGITALQPFHTVERLYEH
                     ISIIFNIIVVVGMNLFTILGSQFKTAGSFGPCILCNRDDYFLSGGHKKIEGAIMDDLAL
                     GEAFLDQDLPVRCLGGKGIISLRMYPEGVGSLIEGWCKSFAVGSKSTHPVVMLMVILWI
                     SGSYTAAGALISSITEWNSVAMMFSGILYILYTIQTAWFARRVGNFRWMIFPFYPILFL
                     FFAGIYLYSFIRVNVFHSVRWKGRKIKV"
     misc_feature    complement(6345..6365)
                     /note="TFBS match to MntR, Manganese transport regulator,
                     confidence: weak, score: 26.6"
                     /tool="antismash"
     gene            complement(6375..7901)
                     /gene="crtI"
                     /locus_tag="MVE64_RS00075"
                     /old_locus_tag="MVE64_00075"
     CDS             complement(6375..7901)
                     /EC_number="1.-.-.-"
                     /GO_function="GO:0016166 - phytoene dehydrogenase activity
                     [Evidence IEA]"
                     /GO_process="GO:0016117 - carotenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="crtI"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) DAO"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1222: dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009792318.1"
                     /locus_tag="MVE64_RS00075"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MVE64_00075"
                     /product="phytoene desaturase family protein"
                     /protein_id="WP_247342486.1"
                     /sec_met_domain="DAO (E-value: 2.9e-09, bitscore: 35.1,
                     seeds: 521, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSKKVIVVGAGVAGLASAIRLQHAGYQVEIYEKGLTPGGKMNRIE
                     LDGYTFDLGPSIVMMPELYRELFELCGRNPDDYIPMEKLDPIYRAYFSDIPDKPFDISS
                     DLAELTKTIESISEEDTAGFFQYMQEIYKRFVIAKHHVLQRPFRKRGDFYNLPMLKKVL
                     KLKPYDTADTFIGKYIKNERLKQLISFQTLYIGISPLKSPSFYTMIPMIQFLYGVWFMK
                     GGMYTMALAMERLFRELGGTIHYGKNVQEISIHNRTAEGITVDGQKISSDYVVCNADFP
                     YAMKHLVKEKSAKGKYTDKKIDSMKYSCSCFLLYLGMDRKYEEIDHVHNFIFNENLNQN
                     LKDIFDGKKLTNASFYVYIASKMDPSLAPEGKDGLYILMPVSDKATANYEWDEETISYY
                     RSYIFNELKKIRGFENIENEIVTETHTTPLDFESKFNAYNGATFGLQPILKQSNHYRPQ
                     SKATHCDNLYFTGSSTHPGAGVPIVLLSARITAQELIQDDTGNLFDYSAI"
     gene            complement(7932..8336)
                     /locus_tag="MVE64_RS00080"
                     /old_locus_tag="MVE64_00080"
     CDS             complement(7932..8336)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF040142.3"
                     /locus_tag="MVE64_RS00080"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MVE64_00080"
                     /product="glycosyl-4,4'-diaponeurosporenoate
                     acyltransferase"
                     /protein_id="WP_281730430.1"
                     /transl_table=11
                     /translation="MCNKLPLAWFLKDTFWFRIFSWEKYGELWQRLFRVKAWKGYLIDG
                     TIFLKKGYSKKSLHGIGAGDLILFAAETKRAELTHWLSILPAPLFFFWNPVGAGWMMIL
                     YALCFNLPIIVVQRYNRGRITAITSEFDKR"
     gene            complement(8515..10011)
                     /gene="crtI"
                     /locus_tag="MVE64_RS00085"
                     /old_locus_tag="MVE64_00085"
     CDS             complement(8515..10011)
                     /EC_number="1.-.-.-"
                     /GO_function="GO:0016166 - phytoene dehydrogenase activity
                     [Evidence IEA]"
                     /GO_process="GO:0016117 - carotenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="crtI"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1222: dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009792321.1"
                     /locus_tag="MVE64_RS00085"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MVE64_00085"
                     /product="phytoene desaturase family protein"
                     /protein_id="WP_247342491.1"
                     /transl_table=11
                     /translation="MKNKTVLVIGGGLGEFSAAISLAQSGYEVSLYEKNDHIGGKLNRL
                     DQDGFGFDLGPSILTMPHIFEKLFSASGKSMKDYVPIEKLDHQWRSFFPDGNIIDLYED
                     LKEMQAKNPSLSEKDMREYQDLLRYSKRLYDMTDKTYFQHGADKTREIMKHTSLFTVLK
                     NFDLFSTVHGGIDKRISNEQFRDMLSYFIKYVGSSPYDAPAVLNMMIYMQHDQGVWYVP
                     GGLHKLANGLVKLAEEVGVQFHLGRKIVRLEKKNGEITGAVLEDGTKLTANYYVSNMEV
                     IPVYERLLEEDNHFVNKLKKKFEPASSGLVMHLGVKKSYPQLRHHNFFFAENMKQQMQS
                     IFHRHELPDDPVIYLVNVNKTDPAQAPVGHENIKVLPHIPYIRNRKPFTQQDYEQFAEQ
                     VLIKLEKMGLHDLRENIVTKDVWTPEDIRRMYGSDRGAIYGTVSDRKKNKGFKHPKQSE
                     RYHNLYFVGGTVNPGGGMPMVTLSGQLVGKKIVQRDSSSA"
     gene            complement(10001..10897)
                     /locus_tag="MVE64_RS00090"
                     /old_locus_tag="MVE64_00090"
     CDS             complement(10001..10897)
                     /EC_number="2.5.1.-"
                     /GO_function="GO:0004659 - prenyltransferase activity
                     [Evidence IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /GO_process="GO:0008299 - isoprenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: phytoene_synt"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: PT_phytoene_like"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009792322.1"
                     /locus_tag="MVE64_RS00090"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MVE64_00090"
                     /product="phytoene/squalene synthase family protein"
                     /protein_id="WP_247342493.1"
                     /sec_met_domain="phytoene_synt (E-value: 1.5e-60, bitscore:
                     203.0, seeds: 8, tool: rule-based-clusters)"
                     /sec_met_domain="PT_phytoene_like (E-value: 4e-82,
                     bitscore: 274.1, seeds: 61, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEKKQRQADFHYCERIIKKHSKSFYYTFSQLPCEKANAVYAIYAF
                     CRTADECADGKHSSQKKIKLLSQLKKELDLFNNQEELDKPLWRALRHVFNTYDMDIRPF
                     YDQLTGQSMDLTFTPPNTMNDLEKYSYYVAGSVGLMLLPVIASKSSEDLRLAVTNLGVA
                     MQITNVLRDIGEDYHQKNRIYLPKEVLTYFQYSQSDLHNSLINDNFINLWEKLAARAEL
                     LYNKFLLSIELLDPDSQLPVCLSAHIYRGILDAVRNNGYQCLTTRNYVTKENMVQINTE
                     VNNIFDLREGDALTVEK"
     gene            complement(11084..11290)
                     /locus_tag="MVE64_RS27235"
     CDS             complement(11084..11290)
                     /GO_function="GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF019474.4"
                     /locus_tag="MVE64_RS27235"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="alpha/beta hydrolase fold domain-containing
                     protein"
                     /protein_id="WP_345740845.1"
                     /transl_table=11
                     /translation="MLIAEYDAFRPEAEYYSEKLKASGVNVHEEIFKGCTHAFTHLGPK
                     ERAEEAWKLVAEKIRAAATSYEN"
     gene            complement(11281..11970)
                     /locus_tag="MVE64_RS27240"
     CDS             complement(11281..11970)
                     /GO_function="GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1066: alpha/beta hydrolase domain-containing protein"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF019474.4"
                     /locus_tag="MVE64_RS27240"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="alpha/beta hydrolase fold domain-containing
                     protein"
                     /protein_id="WP_281730431.1"
                     /transl_table=11
                     /translation="MFTVMIAKLLRFLPNQAKKTHMIPLQQVKMKKDVVVETSVHPTNI
                     SLYYPLEAKQKKFPVYINFHGGAFIMNEKEMDDPYCRYLANQAECVVLNVDYAKAPEFP
                     FPKPIEQGYEIIQWLKRRAEDLNIDAGKFMVGGQSSGANIAAALCLYLEEKGEHQPLLQ
                     VLSCPMLDFATPHADKPEPDKWRARYPQVAHFLNMCYVPDKGQAEHPHASPVRAEMSGR
                     LASLLFL"
     gene            complement(12360..13283)
                     /locus_tag="MVE64_RS00100"
                     /old_locus_tag="MVE64_00100"
     CDS             complement(12360..13283)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PhyH"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF017532.4"
                     /locus_tag="MVE64_RS00100"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MVE64_00100"
                     /product="phytanoyl-CoA dioxygenase family protein"
                     /protein_id="WP_247342495.1"
                     /sec_met_domain="PhyH (E-value: 5.5e-06, bitscore: 25.0,
                     seeds: 39, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTNYKVLTQEQVNQFIELGWVKVEQAFPKEVALEAQKIVWENVEK
                     RGVTKNDRSTWKEEMVQLNETYEHDEFQKCNTKRLADAIEDLVGEGRWADRTVYGESDK
                     KVGYGWWPVNFSQGALKPWNVPTTGWHWDGIQFHHYIDSPEQGLLCLNLFSEIGKQGGG
                     TLVAEGSHKVIAKFLSQQHDGIELEEGIRALNKQHPWFSELTGSKKDNTTNDEENRIEK
                     FMENPFVDEDGIKLQVIETTGNPGDVILCHPFLYHAASQNHSGIPRFMCNRTTPLTERI
                     NINRADGNYSPLELSIKSVLHKEATI"
     misc_feature    13873..13888
                     /note="TFBS match to CsoR, Copper-responsive repressor,
                     confidence: weak, score: 22.0"
                     /tool="antismash"
     misc_feature    13873..13889
                     /note="TFBS match to RicR, Copper-responsive regulator,
                     confidence: weak, score: 21.55"
                     /tool="antismash"
     gene            complement(13920..15722)
                     /locus_tag="MVE64_RS00105"
                     /old_locus_tag="MVE64_00105"
     CDS             complement(13920..15722)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF019157.4"
                     /locus_tag="MVE64_RS00105"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MVE64_00105"
                     /product="tannase/feruloyl esterase family alpha/beta
                     hydrolase"
                     /protein_id="WP_247342498.1"
                     /transl_table=11
                     /translation="MNKKKRFSILLTVVLVIMSLIPSSVFAESVSVLKVGESEKEENTN
                     KPTTKGGAKDEIPQLAPAQPGNLKQCVNLLETFEFNNTTITSAELIADGTLSNAGKPVG
                     EHCLVKGKMNERVSSVDGQTYAIGFEMRLPVEWAGRFLYQANGGADGNVVTANGSIGGG
                     PLENGLQKGFAVISSDAGHTSAQNVGFGFDPQARLDFGYQAVGTLTPMAKSLIEAAYGR
                     EPDRSYIAGGSNGGRHTMVAASRYADQYDGFLAIAPGFNLPKSAVAQLWGVQQWAKVAT
                     DINNLETALPLAERQVIAEAILDRCDGLDRLNDGIVQDTERCQKVFSVERDVPTCELER
                     DGTCLTVEQKQVVKDVFAGARTSSGEQIYTSFPFDPGLVHNGWGLWKFRISVALDPGTV
                     SHIFLSPPEGFNGKTPPEYALSFDVDNKWQLIYESNDLYTESAMEFMTPPDPTNLDTLR
                     NSGAKMIVAHGSSDGIFSSDDTRRWYKELDANYRNKADEFVRYFEVPGMGHVSGGPATD
                     QFDGLGALIDWVEYGKAPDRIIATARGEGNPGGVNPEVPSTWAPDRSRPLCSYPLVARY
                     KKGDPEVASSFECKPSSGGPGLNR"
     misc_feature    15832..15846
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence:
                     medium, score: 23.04"
                     /tool="antismash"
     gene            complement(15906..16028)
                     /locus_tag="MVE64_RS27245"
     CDS             complement(15906..16028)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="MVE64_RS27245"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_281730432.1"
                     /transl_table=11
                     /translation="MRKMNNINKLIQSLANDVEAIELKHQHSIKDKEVYYFVGR"
     gene            complement(16468..17475)
                     /locus_tag="MVE64_RS00110"
                     /old_locus_tag="MVE64_00110"
     CDS             complement(16468..17475)
                     /EC_number="1.-.-.-"
                     /GO_function="GO:0010181 - FMN binding [Evidence IEA]"
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1251: luciferase
                     family protein"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010281079.1"
                     /locus_tag="MVE64_RS00110"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MVE64_00110"
                     /product="LLM class flavin-dependent oxidoreductase"
                     /protein_id="WP_247342499.1"
                     /transl_table=11
                     /translation="MTINRPSKSINDISFSVLDLASIVQGGTPGQSFQHSVELAQLTEK
                     LGYKRYWLAEHHNMPGIASSATSIVIGHVAAHTSTIRVGSGGIMLPNHSPLVIAEQFGT
                     LEAMFPGRIDLGLGRAPGTDQQTAHAIRGANYTNGDDFPEQLEQLQAYFQGTGPVRAIP
                     GEGANIPIWLLGSSGFSARLSAQLGMPFAFASHFSPENTLPALKLYYDNFQPSEDYKEP
                     YAMVAVNVIAADTDEEAELLASSIKQSFLNMIRNTPSKLQPPLENLDELMSPYEKAILE
                     KQLSSTIIGSPNNVKEKLQSFLDETKADEIMVSTMVYDHNARLYSHKLVAEIMG"
     gene            complement(17969..18763)
                     /locus_tag="MVE64_RS00115"
                     /old_locus_tag="MVE64_00115"
     CDS             complement(17969..18763)
                     /GO_function="GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016743695.1"
                     /locus_tag="MVE64_RS00115"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MVE64_00115"
                     /product="fumarylacetoacetate hydrolase family protein"
                     /protein_id="WP_247342502.1"
                     /transl_table=11
                     /translation="MKTLQKTQSIVRYQRYEKEYYGIIDGDDIVQLSSDFTQIVNNEIN
                     YDGVRVKYNEVKILEPVSPSKIVNFGWTYAGHAKETGGTANLREPFLFLKPTSSIIPDQ
                     GEIILPPTTLTEQVELEGEVALIIGKRGRNIKEEEALDYLFGCTIFNDVTARDLTKSDP
                     QFTRGKGFDTFGPLGPYIVTGIDPTNLRIVTTLNGNVVQDGNTNQMTLSIPYLISWISQ
                     VMTLEPGDVLATGSPSGSCPMKSGDTVVVEVENIGTLCNYVK"
     misc_feature    complement(18920..18935)
                     /note="TFBS match to ColR, Phenol-responsive regulator,
                     confidence: weak, score: 22.29"
                     /tool="antismash"
     gene            complement(18981..20393)
                     /gene="nhaC"
                     /locus_tag="MVE64_RS00120"
                     /old_locus_tag="MVE64_00120"
     CDS             complement(18981..20393)
                     /GO_function="GO:0015385 - sodium:proton antiporter
                     activity [Evidence IEA]"
                     /GO_process="GO:0006814 - sodium ion transport [Evidence
                     IEA]"
                     /GO_process="GO:1902600 - proton transmembrane transport
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="nhaC"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006639603.1"
                     /locus_tag="MVE64_RS00120"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MVE64_00120"
                     /product="Na+/H+ antiporter NhaC"
                     /protein_id="WP_247342503.1"
                     /transl_table=11
                     /translation="MKSVRLPTILEIVCTLGLFLVIVFSFTAFFDLPIQLALFISWFLV
                     ILLGFKLGYRYEELQKAITTGISNGLEAILILVAVGALIGTWIAGGVVPTLIYYGLEFI
                     HPSIFLLATLIVCSITSLATGTSWGTVGTAGIAMMAIGEGLGMPLPLVAGAVLSGAYFG
                     DKLSPLSDSTVLAASLSKVEVIAHVRAMLYLDIPAYLITAILFTVAGFIYGGNNTDLEK
                     VEFLKLALLDTFNIQIWMVTPAIFVIVMLAMKKPSVPSIAIGALLGAIWAVVFQGMNVP
                     DAVGTAYNGFSINTGVEFMDKLLNRGGIEGMLGSVAVIIFGLGFGGLLEHLGVLKVIIS
                     KFHSFLTSAGNVTLSTIIVAFFANVFGCAMYVSLILTPKIMGESYDNLHIDRRVLARNT
                     EVGGTLTSGMIPWTDNGIFMAGILGVSTFAYVPFMWLSFVSIALAIIYGYTGKCIWYVK
                     QKQGEGQIQQTF"
     misc_feature    20494..20508
                     /note="TFBS match to MexT, Global virulence regulator,
                     confidence: medium, score: 20.1"
                     /tool="antismash"
ORIGIN
        1 ttctttaatt attgtagaga aagatttttg agcctgagtc agaatctctt cacgatgtgc
       61 aataaataaa acacgtttaa accttttcgc aaaaaaacca gctaaatatg tcttacctaa
      121 tcctgttgcc attactacta gagctgattt gtacccttca tcataggttt tttctaactc
      181 ctccagagct tcaacctgtg caaaacgtgg ctggatttca ccatagtcag ctgattcctc
      241 tgctatatgc atttcttttt ctttactagg gagcattagt tcaatttcct ctagctctga
      301 ccattttttc gcaagattcg ggtgcttttc gtggtacttt tcatagtttt cctcgaagct
      361 ttttatcgtt tctacattaa ctggtatcgt ctgttcatga tacattagct ttgtaaattg
      421 atccattgct tctttgaaga cagctggctc tttattaatc gaaacgttcc actctattcc
      481 acttgttaag gctgatcttg atagattgga agaaccaata acaagatgac cttcctcatt
      541 aaggtgaaaa agatatgcct ttggatgaaa agaaattcca ttactgttcc aaagtctaac
      601 ttcaatttta ggattaattt caactagtga ttttaatgct tcggtactgt gtgatatata
      661 aataatctcc tgtacatatt ttgatatcaa cgcctctttc agcagcacgt ttaagtggtt
      721 cacgaagcag ctcgacccct gatttcataa caaaagaggt taaaatacaa atggttgaag
      781 cttgttctat tttctcaagt agatgtgaaa taagctgatc tgttattaac tctaccttac
      841 tcatcttcaa cctcaattaa gtatattttc tctttaaaac caccacgttc ttgtgctttc
      901 ttagctctaa ttttctcaac ttcgctgatt gatgagccat gaaattccgc tagtgcatgg
      961 acgatttcta aaagatcagc taattcttca agagagctgt ccttgtcgtt tgcttccaca
     1021 tactcttgta actcttcaaa ccctttttct tgtagctttt ttatgtatac ttcatgggat
     1081 aagatagaag ttttataagc tttcccggtt ttctcaataa tttctggaat tctgtctcta
     1141 acaagcttgt tatatactgg catattccta ttctcccttt agtaggttct tttatctgga
     1201 ataactcccc ttactccacc acgtgggtct ttcatatctc ctttatatct tggaataaga
     1261 tgaacatgga catgaaagat ggtttgccct gctacttcac cgttatttat tccgatgttg
     1321 tatccgtctg gtttgtgttt cttatctaat aaagcatttc cttcaaataa taaggaatca
     1381 attgcttgtc tttcttctat ggttaaatca aaatattgct ccacatgccg tttaggaatg
     1441 attagtaagt gtcctttgtt tactgggtat atgtcgtaaa aggcaatgga taagtcgttt
     1501 tgtaatacgg gctctatatt cgaacaaaat ggacagttca tgttgaaatc tccctaatta
     1561 attattttta tatctatgtg ttatagctta atcttacctc attcgacaat tattgttaat
     1621 tccctataca acagcagaac taatttcgtt aatgaaggat gttaactaga aataaaaaat
     1681 agtgtgaagc taaagttata aatcttcttt ttaaaagagt tgttttctat taaaaaagaa
     1741 gatgaacact acgtgtagta gaaagtcatc tccaattagt taaagccata ttcattttta
     1801 cctgtaaaca gctcattaag ttcatataag tctgttgtct ctcatctatt ttttgtttat
     1861 ccaaacaagc ttttcttctg gctcgcgatt agaccatgcg taatatgtaa tgacttttat
     1921 cttcagctat ttaaactcgt attaaacttt aaagatcttt atcataaata caagaaaata
     1981 aagtctgttc cctaaaaatt ttgaaacaga ctcataatct accaagttct tatcaatctc
     2041 agttgtacaa ataaaaggag caagccctcc tattagttaa acgagacatt caccgtataa
     2101 ccatcattct taaaaaattc ctttaacact ttttctgcat ttttctctgc actatctaat
     2161 aatccactag agatggctcc ttgtcgaatt ttctcttgtg cctcagcagc caactcaaac
     2221 ccctcattca tttttatatc atcacggaaa agcccattct tgtccacggc ttgtatttta
     2281 tccatctgta cagatggttc ctggatgatc tctgcatgcg gaagagtaat atctatttct
     2341 tttgtttctt cattaatatc caagtcctta gaagtaattc ctttcaaatc aacacctgca
     2401 atcaccgtcg caggtacaac caatagaact tctcgctttg ttcctggtaa atcaatattc
     2461 aagaaattct tattttcttc ttggtgtaga acctctttca tatgagcttc agctgttgcc
     2521 aatgttgcta actcttgaac acgttcaaca aacgtgacag actcttgttt gatggtactg
     2581 cctgcaaatg gccggaatac tccgaaagcg atgataaaag ctactaaaat aacgatggcc
     2641 agaattaaaa tattcttcaa tctaccaatt tttaagagag acttagattt tcctatcggt
     2701 ggtgaaacat atcttgagtt ttgatctacc gcaatagttg cagcaatttg ctgtgttgct
     2761 tcatataatt cttttatctg tctttctagc tgtgcaattt tttcgtcttt ttcttcgatt
     2821 atttctctac ttgtattcat tttttcacct ttcatttacc attgaatgcc tatcctttta
     2881 atccactaat ctattatgtg gggaaaattt ttaacttata aatattaatt acgaagaagc
     2941 actaagacct tttaaataca atttagcgat ttgctcctgt tcgataattc tccaccttac
     3001 ctcttctgca aatcattacg tagctgctcc accctttcat ccacctcatc ataaaagtca
     3061 gatgaaaggt caccaatgat aaagagataa gcaagggaag catctgaatt tctaatacat
     3121 ctttccaaat cgtcaagtgg ccttttcgta ttcactttcc cttgataatt tttacattga
     3181 actgggatgt cgtcatgtag gatgaaccca tcaagtgggt ccattattct catcgttaaa
     3241 tcccagccct ttccactatc accttgtttc tttacttcca gtccaggtgt ggcatttatt
     3301 aaatctgcta caaactgttc aaaataagca cttggccaat tctttgaaat tctcttatat
     3361 gtctgagcga ctaccgactc ttctaaagca gttctctcat aatcaatcga tctaagactt
     3421 tgatttgcct tatgaaaact ttcatcttct tccatcgatt tcttcactat taaatcaagc
     3481 tcttccttag aatcctcatc atatatttcg taataatgcc ctcgcttaga aagatggtga
     3541 cggagagatt gtgaaacagc ttctgatttc acttgaataa aagaattcgt tagaagttta
     3601 cattgaacat aatgattaaa atctttctct tgtggatctg tagaaccata ttccccaact
     3661 atttcagcaa taagaaattg tcttagcggt tgaccaagct gtatgatgag acgatctcca
     3721 gctttaagtc tattaatcaa aaactgtgta tatctccaaa ccactttctc ctttgtggac
     3781 ctctctttag cctctttact cttaatgata tgtaaattgg accccggcga actccaacca
     3841 aaccttgcac gtccttcatt tagttccttg atcatccatt cttcttgccc atttctaatt
     3901 gatacatatt taaaataccg tgtcatttta ttcacctctt tataaatgct gattaataat
     3961 catcctatta atctattttg ttcaactaac tgtaaaacct ttactagact taaaaataaa
     4021 tggactccat tctaaaaata catataatta caagattcta caaaaaacca caaaaccctt
     4081 ttttcgaatt gaatgctggt agggaattga taaagcgaaa tatcaaaaag gatagctcaa
     4141 taacacctat catgaaaaga agccgttcac aacactgtga aaaggcttga cactgttttt
     4201 cgacttttct atttatagtt ttttcattct aatagattca agtatgattt aataaggtaa
     4261 ttagtgagat aataagaaga gcaaccatta aggagcgaat gtgaagtgaa aagtataatt
     4321 aaaaaaacag ctattatttt ctccatcttc atcatcataa gcttattggg attgtggata
     4381 tggtcacaac aaacgtataa gccgtctgag caattatttc aacttgttga accaactagc
     4441 ataatttaca aagaagattg gattgtcttt caaccacaaa atgacccagt agctggactg
     4501 attatttacc ctggtgcaaa agtggagcct gaagcttata gttatttagg aaagcagcta
     4561 tctcttgaag gatatgttgt attcatacca gagttcacct ttaattttcc gattcttgat
     4621 tcaaacaaag cacaagaaat aatcactcac tatcctgaaa taaagcactg gtttgtgggt
     4681 ggtcattcat taggaggagt atcggctgcc atgtttgctc aaaatcatat aaaagaatta
     4741 accggcctga tcctattagg ttcttatcct agtaacgaag atcgtttttc atccgtcgat
     4801 ttccctatat tatctattta tggagaaaaa gatgggctta caactgttga taaaattaaa
     4861 gaaaccgaag agctcctctc tacaaatgca caattggttg aaattcaagg aggaaatcat
     4921 tcacaatttg ggatatatgg atttcaaaag ggcgatcata aagcaacgat ttctgctaaa
     4981 aaccaacagc aacaaatcat agatatcatc tcaaaatggc taggagacac cttgaatgaa
     5041 tagaaaactt attaatttta gaaggaagta tttttcccat catgcgtaga atggtgaaac
     5101 attaaacaaa ctatcctctt aggggtactt ttttcatagg aacgatcctg ctttttattt
     5161 taattttcat aataaatgta tgatccccgt gcaaatgatt aaggatgttc agaccttaat
     5221 tttacgcccc ttccatctta cagaatgaaa aacattcact ctgatgaagg aatacagata
     5281 aattcctgca aaaaacaaga acaatattgg ataaaagggg aaaatcatcc atctgaaatt
     5341 accgactctg cgtgcaaacc atgccgtttg aatcgtatac aggatataca agataccact
     5401 gaacatcatg gcgacagagt tccattcagt aatcgaagag atcaatgctc ccgcagctgt
     5461 ataactgccg gaaatccata gtatgaccat gagcatgaca accggatgag ttgacttgga
     5521 gccgacggca aagcttttgc accagccctc gataaggctt cccactcctt ccggatacat
     5581 gcgcaaagag ataattcctt tgccgcccag gcagcgaacc gggagatctt gatcaagaaa
     5641 tgcctctcct agtgccaaat catccatgat ggctccttca atttttttat gccctcccga
     5701 caaaaagtaa tcgtctcgat tacatagtat gcacggacca aacgaaccgg cggttttaaa
     5761 ctgcgatccc aaaattgtaa aaagattcat ccctaccacg acgattatgt tgaatataat
     5821 ggagatgtgt tcatacaaac gctcaactgt atgaaatggt tgtaatgctg tgatgccttt
     5881 ggcccccttc tgctggtaaa aatgcagtag attgctcaat ccatccacac tggtgaatct
     5941 cgtatctgcg tctaaaaata ataaccagct ccctttggcc tgcttagcac cttgccagca
     6001 ggcagaggat tttcctgcac ctgcattctg cagaaccttt gcaccatagc tttccgcaac
     6061 agatgcagta ttgtcagatg aatcgtcatc aacaaccaga atttcaaatt gtctgaaacg
     6121 ctgctcctgc aatgattgca ataacggtga aatcctacct tcttcattcc tggctggaat
     6181 aatgatggac agaaacggaa ggcctgccgt aggcctagag gtaaaaccgg gaaccggcaa
     6241 agaccagaac atgagaaccc caactaccac tgccgcaaat ccaattgcga gattaatcac
     6301 ttctgaaacg gtcataaaac ctacctcctt cctttgagtg taagcacata gcttttgtta
     6361 tctctagtta gtctttatat tgctgaataa tcaaataaat tacctgtatc gtcttgtatc
     6421 agttcctgtg cggtgattct agcggataac aggacgattg ggacaccggc gccgggatgt
     6481 gtgctgcttc cggtaaagta caaattatca caatgagtgg ccttgctttg cggacgatag
     6541 tggttgcttt gtttcaagat tggctgcaaa ccaaacgtgg ccccattata agcattgaat
     6601 ttcgattcaa aatctaatgg tgttgtatgc gtttctgtga caatttcatt ttcaatgttt
     6661 tcaaaaccac ggattttctt taattcattg aaaatgtaac tgcgataata agaaatggtt
     6721 tcctcgtccc attcataatt tgctgtagct ttatccgata cgggcatcag gatatacaat
     6781 ccatcttttc cctcaggtgc aagggaagga tccatttttg aagcaatata tacatagaag
     6841 gaggcattcg tcagcttctt tccatcaaat atatctttaa gattttgatt taggttttcg
     6901 ttgaaaataa aattatgtac atggtcaatt tcttcatatt tccggtccat accgagatat
     6961 aacagaaagc atgaacaaga gtatttcata ctatcgatct tcttatcggt atattttcct
     7021 ttggcagact tttcttttac caagtgcttc atcgcatacg ggaaatcagc attacaaaca
     7081 acataatctg aagagatttt ttgtccatcc acagtaattc cttccgctgt gcgattgtga
     7141 atcgatattt cctgtacatt cttgccgtag tgtatggttc ctccaagttc cctaaagagt
     7201 ctctccatgg ccaaagccat cgtatacata ccgcctttca taaaccatac tccatataga
     7261 aattgaatca taggaatcat ggtgtaaaaa gaagggcttt taagaggaga aatacctatg
     7321 tacaacgttt gaaaactaat cagctgtttc aggcgttcat tcttaatata ttttcctata
     7381 aacgtatccg cagtgtcgta aggcttcagt ttcaacactt tcttcaacat cgggagatta
     7441 taaaaatcac cccttttacg gaaaggtctt tgaagtacat gatgttttgc gatgacaaag
     7501 cgtttataaa tttcttgcat atattgaaaa aaacctgccg tatcttcttc gctgattgat
     7561 tcaattgttt ttgttaattc agcaaggtca gaggagatat caaatggctt gtcgggaata
     7621 tcactgaaat aagcccgata aattgggtcc aatttttcca ttggaatata atcatcaggg
     7681 ttacggccgc aaagttcaaa tagctcccga tataattccg gcatcatcac gatgcttggg
     7741 cccaaatcaa atgtgtagcc atccagttca attcgattca ttttgccgcc gggtgttaat
     7801 cctttttcat atatttccac ctgatagccc gcatgctgca gccttatggc acttgcaagg
     7861 cctgctacac ccgctccaac gacaatgacc ttcttactca tgtaaattcc tcatttcaaa
     7921 aaatattctg ctcatctctt atcaaactct gaagtaatgg cagtaatacg cccccgattg
     7981 tagcgttgaa caacgataat aggaaggttg aagcaaaggg catacaggat catcatccag
     8041 cctgccccta ctggattcca aaaaaagaac agaggagcag gcagaatgga aagccaatgt
     8101 gttaactctg ctcgttttgt ttccgcagca aagagaatta aatctccagc tccgatgccg
     8161 tgtaagctct ttttactgta tcctttttta agaaaaatcg tgccatctat aagataacct
     8221 ttccatgctt tcacccgaaa taaacgttgc cacaattctc cgtatttttc ccaagagaaa
     8281 atccgaaacc aaaaagtgtc tttcaaaaac catgccaaag gcagcttatt gcacataaca
     8341 gaaatggaca gatggaaaat tgtccatgct aatacatcta tgataatgat tcaaaggatg
     8401 ggaaatgata cgaccatggt atccccctta tgtttaaagg cacaattgcg tttaataaga
     8461 gaagctttct tcatccagct ttatgcaaaa gtctttagta aatgactaaa cctgtcaggc
     8521 agatgatgag tctctttgaa caattttctt gcctacaagc tgaccgctta acgtgaccat
     8581 cggcattcct ccgccggggt ttacggttcc accgacaaaa tataaattgt gatagcgttc
     8641 actctgtttt ggatgcttga atcctttatt tttcttacga tctgacacgg ttccataaat
     8701 cgcccccctg tcagagccat acatccgcct aatatcttcc ggtgtccata catcctttgt
     8761 aacgatattc tcacgcaaat cgtggagtcc cattttctcc aatttgataa gcacttgctc
     8821 agcgaattgt tcataatcct gctgtgtgaa aggtttacga tttcgaatat aaggaatatg
     8881 tggcagtact tttatatttt catgtccaac tggcgcctgc gctggatctg ttttattgac
     8941 gttaaccaaa taaatgaccg gatcatccgg aagttcatga cgatgaaaga ttgattgcat
     9001 ttgctgcttc atattttctg cgaaaaagaa attatgatgg cgcagctgcg gatagctctt
     9061 ttttacgccc aaatgcatca cgaggcctga gctggctggc tcgaatttct tctttaattt
     9121 attcacaaaa tggttgtctt cctctagcaa tcgttcgtat actggtatga cttccatatt
     9181 agaaacataa tagttcgctg ttagctttgt tccatcttcc aaaacggctc ccgtgatttc
     9241 accgttcttt ttttcaagcc taacaatctt tctgccaagg tggaactgaa caccaacttc
     9301 ttcagccagc ttcacaaggc cattcgccag tttatgcaaa ccaccgggta cataccatac
     9361 accctggtca tgctgcatgt aaatcatcat gtttagaaca gccggtgcat cataaggaga
     9421 cgaaccaaca tacttgataa aataagaaag catgtcccga aactgttcat tacttatccg
     9481 tttatcaatc cctccatgaa cggtagaaaa aagatcaaag ttctttaaaa cagtgaacag
     9541 gctcgtatgt ttcatgattt ctctcgtctt atcggcacca tgctgaaaat aggttttatc
     9601 cgtcatatca taaagtcttt tcgaatagcg aagcagatct tgatattcac gcatatcctt
     9661 ttcactcagg gatggatttt ttgcttgcat ttccttcaag tcttcatata aatctatgat
     9721 atttccatca gggaaaaagg agcgccattg atgatctagc ttttcaatcg gaacgtagtc
     9781 cttcatggat tttccacttg ctgaaaacaa tttttcaaag atgtgtggca ttgtaaggat
     9841 ggatggaccc aaatcaaaac cgaaaccatc ctgatccagt cggttcagct ttcctccaat
     9901 atgatcattt ttttcatata aagagacttc gtatccagac tgtgcaagtg aaatcgcagc
     9961 cgagaattca ccgagtccgc ctccgataac taatacggtt ttatttttca actgttaatg
    10021 catctccttc tcgcaaatca aagatgttgt tcacttcagt gttgatttgg accatgtttt
    10081 ctttcgtaac ataattcctc gttgttaaac attgatagcc attgttccgt acagcgtcaa
    10141 gtatgcctct gtatatatga gcagacaaac atactggtaa ttggctatca ggatccagca
    10201 gctctatact taataaaaac ttgttatata ataattctgc acgtgcagca agtttttccc
    10261 ataagttgat gaaattatca ttaattaagc tattatgtaa atcactttgt gaatattgaa
    10321 agtatgtaag tacttctttg ggcaaataaa tgcgattttt ctgatgataa tcttcaccaa
    10381 tatctcgaag tacattggtt atttgcatgg ctacacctag atttgttacc gctaaacgta
    10441 gatcttccga agatttcgaa gcgatgacag gtaaaagcat taaaccaaca gatccagcta
    10501 cgtagtaact gtatttttcc aaatcattca ttgtgtttgg gggtgtaaat gttaaatcca
    10561 tggattggcc tgtcagctgg tcataaaagg ggcgaatatc catatcatac gtattaaata
    10621 catgtctaag tgcgcgccat agaggtttgt ccaattcctc ttgattattg aacaaatcta
    10681 gttctttctt taattgactc agcagcttaa tctttttttg ggatgaatgt tttccatctg
    10741 cacactcatc tgcagttctg caaaaagcat agatcgcata aacggcattt gctttttcac
    10801 aaggtagttg tgaaaaagta tagtaaaagc ttttggaatg tttttttatt attctttcac
    10861 aataatgaaa atccgcttgc ctttgctttt tttccatatc gatctccttc agatctattt
    10921 acagatcaat gaaatatgat aaagcgttga ttggatttgt tttcctattt tctcctgctc
    10981 caagtctgca acctttaaat gatcttttcc ctgattccct cacgaaaaac ttgaatgtgt
    11041 ttcaaaacat attttaaaaa ggaggaataa cgaagaaggt gctttaattt tcataggatg
    11101 tggccgccgc tctgattttc tctgcgacaa gtttccaagc ctcttccgct ctttcttttg
    11161 ggcctagatg ggtaaaagca tgtgtacagc ctttgaatat ttcttcatga acgtttactc
    11221 cagatgcttt taatttctca gaataatatt cggcttcagg tctgaatgcg tcgtactccg
    11281 ctataagaat aagagtgaag ctaagcggcc actcatctct gcacgaacag gggaagcatg
    11341 tggatgctcc gcttgtcctt tgtcagggac atagcacatg ttcaaaaaat gtgctacttg
    11401 aggatatctg gcacgccatt tatccggttc cggtttatct gcatgggggg tggcaaaatc
    11461 cagcatcggg caagacagta cttggagcag tggctgatgt tctcctttct cttccagata
    11521 aagacaaagg gctgctgcaa tatttgcccc agaactctgt ccgccaacca taaattttcc
    11581 cgcatcaata ttcaaatcct cggctcttct ttttaaccat tgaataattt catagccctg
    11641 ttcaattggt ttgggaaaag ggaactctgg tgctttcgca taatcaacat taagaacaac
    11701 acattctgcc tgattggcta ggtaacggca ataaggatca tccatctcct tctcattcat
    11761 gatgaacgct ccaccatgaa aattgatata gacagggaac tttttctgtt tggcttccaa
    11821 aggatagtac aaggatatat tagtaggatg aacagatgtt tcaaccacca cgtctttttt
    11881 cattttcact tgctgcaagg gaatcatatg tgtctttttt gcttgattag ggaggaaacg
    11941 cagtaatttt gcaatcataa cagtgaacat aagtgtaacc tcactttttt aacattttaa
    12001 ctgcaatgaa acacatttat actccgaacc tcactttttt tatcaattaa ttggaattaa
    12061 acagatatat actccgaacc ctcattgctt agcaatggaa aaaaatcata tttaattgaa
    12121 gacaaaatgt cttccggtga cctgtttacg gaatgacgta cttaggatag aatttggcgt
    12181 ttcatccttc tagacttgtt tactttaata aaaaaacgtc taaacccagt aatatcatgg
    12241 atttaagacg ttttatctta ccggatttag ttgtagtgtg atgtagcaaa tacagaagta
    12301 gatctttgga gtacaggtag gagctgctaa atacttgcag ttcctctatt actagtttgt
    12361 tatattgtag cttctttgtg taaaaccgat ttaatactca actccaatgg tgaataattc
    12421 ccgtctgccc ggtttatgtt aattctttca gttagtggag tagtccgatt acacatgaaa
    12481 cgaggaatgc ctgaatgatt ctgtgaagca gcatgatata aaaacgggtg gcataaaatc
    12541 acatctccag ggtttccggt ggtttcaatc acctgaagct tgataccatc ttcatcaaca
    12601 aacggatttt ccataaattt ctcgatccga ttttcttcat cattcgttgt gttatccttt
    12661 ttagagcctg ttaattcgga aaaccacggg tgctgcttat tcaaagcacg gatgccttct
    12721 tcaagctcaa ttccgtcatg ttgctgggaa agaaattttg ctatcacttt atgtgaacct
    12781 tctgccacaa gtgtgcctcc accttgtttt cctatttcag agaataaatt taagcaaagt
    12841 agcccttgtt caggactgtc aatataatgg tgaaattgaa taccatccca atgccatcct
    12901 gtagtcggta cattccatgg tttgagagca ccttgagaaa aattaactgg ccaccatcca
    12961 tagccaacct tcttatcact ctctccatat actgtcctgt ccgcccatcg cccctccccg
    13021 acaagatctt caatggcatc tgctaatctt tttgtattac atttctggaa ttcatcatgt
    13081 tcataggttt catttaattg aaccatttct tccttccaag ttgaacgatc attctttgta
    13141 actcctcgtt tttcaacatt ttcccaaaca attttttgag cttctaacgc cacctcttta
    13201 ggaaatgctt gttcaacctt tacccagcct aattcaatga actgattaac ttgctcttga
    13261 gttaacacct tataatttgt caaagtactt cctcctttaa atatggatag atccaaaaga
    13321 ataaagcata tcttttttaa ccattactta ccttcttccc actatttaga gactttagtt
    13381 ttaacagttt tcacatggtc gaagataaaa taataaggtg gttcatcctt cctttcgaaa
    13441 tagataacaa aagaaagtgc tttcatttat tggtgctgat gatcatgctg cttgcttagt
    13501 attcttatat tataatagat ttcacttagt ttgtctgtca aataaagtaa gtttgctatg
    13561 tttttatata aattaggatt ttacttggtt cgtaatatca tttcctagaa cagtaaggtt
    13621 gtactgtaca acaaatgact tggtttttac tatttttaca atagtcccca ttactttaga
    13681 tagaaaaatt gtattgagta aaggaacaga cagataacac tcctgaaggt gacaatgctg
    13741 ggtttatgta tttttagatg atgtgattta aactcacatg atatcttaaa gggttaactt
    13801 tttttgccat tgaaaaatcc cctaaaggta gactattaag aacacaatac catgctctct
    13861 tttttatcat gtctacccgt aggggctaat aaagcatatt atcatctgta ctgaaaggac
    13921 tatcggttga gaccaggtcc tcctgaactc ggtttgcact cgaaactgct tgccacttcc
    13981 gggtcgcctt ttttatagcg agccactaat ggataagagc ataaaggacg agaacggtcc
    14041 ggtgcccatg tggaaggtac ctcagggtta acaccgcctg gatttccctc acctcgcgct
    14101 gtcgctataa tacggtccgg tgccttgccg tattcaaccc aatcgattaa agcgcctagg
    14161 ccatcaaact ggtcagttgc aggaccgcca ctgacatggc ccatgccagg cacctcaaaa
    14221 tatctgacga actcatcggc tttgttccgg tagttcgcgt cgagttcctt gtaccagcgc
    14281 cttgtgtcat cagaggagaa gataccgtct gatgaaccgt gtgccacgat cattttagct
    14341 cctgaattcc gcagggtgtc caaattcgtt ggatcaggcg gcgtcataaa ttccatggca
    14401 ctctctgtat acaaatcgtt agactcatag ataagttgcc atttattgtc cacatcaaag
    14461 ctaagagcat attccggtgg cgtttttcca ttaaaccctt cagggggcga taggaaaatg
    14521 tggctaacag ttcctggatc gagagcaacg gaaattctga acttccataa cccccaccca
    14581 ttatgaacaa gtcccggatc aaatgggaaa gaagtgtaga tctgttctcc tgagctagta
    14641 cgagcgcccg caaaaacatc cttcacgact tgcttctgtt ctaccgttaa gcaggtgccg
    14701 tcccgctcca actcacaagt aggtacgtct cgctcaacgc taaagacttt ctggcaacgt
    14761 tcagtgtcct gtacgattcc gtcgtttagc cgatcaagac catcacaacg gtctaaaatc
    14821 gcctctgcga taacttgacg ctcggccaaa ggtagcgctg tctccaagtt gtttatgtct
    14881 gttgcaacct ttgcccattg ttgaactccc cacagctggg ctaccgcgga cttgggcaag
    14941 ttaaatcctg gcgctatggc taaaaaacca tcgtactgat ctgcatagcg tgaagcagcg
    15001 accatggtgt gacgcccgcc atttgagcct ccggcaatat atgagcggtc aggctcgcgt
    15061 ccatacgcag cttcaatcaa gctcttagcc ataggtgtaa gcgttccgac tgcttggtaa
    15121 ccgaagtcaa gacgtgcctg cggatcaaat ccgaacccaa cgttttgagc tgaagtgtga
    15181 cctgcgtccg agctaatgac agcaaagccc ttttgcagtc cgttttccag cgggccgcct
    15241 ccgatacttc catttgctgt tacgacgttg ccatccgctc caccatttgc ttgatagagg
    15301 aaccgtcccg cccattcaac tggaagccgc atttcaaaac cgatagcata cgtctgacca
    15361 tctacagagc tcactcgctc gttcattttt cccttgacga gacaatgctc gccaacaggc
    15421 ttaccggcat tggacagtgt tccatctgca ataagctctg ccgatgtgat agtggtatta
    15481 ttaaactcaa acgtttctag cagattcaca cactgcttca gattgcctgg ctgtgctgga
    15541 gcaagctgtg gaatttcatc ttttgcccca cctttagttg taggtttgtt tgtattttct
    15601 tctttttcgg attcacctac ttttaaaacg cttacacttt ctgcaaaaac actagaagga
    15661 attaacgaca tgatgacaag aactactgtt agtagaatgg aaaaacgttt tttcttgttc
    15721 atatattttc tcctttcatt ttcgcttgca aagcagttta ttatcgttat agggttataa
    15781 agcttttatt tacctcctct taaaaattat caccacacaa gaattgtaca taatattcag
    15841 aaagttaata agccttatag tgtaggaatt caaacttcaa aattcctaca tagtaattaa
    15901 aggatttaac gacctacgaa ataataaacc tctttatctt ttatagaatg ctgatgtttt
    15961 aattctattg cttcaacatc atttgctaga gattgtatta atttatttat gttattcatt
    16021 tttctcaata aaagaaattc tttctattca tttgttttca aacatttata ccttggttat
    16081 aataatagta gagaaatcat aaactaaaaa agactgttcg gtgctctaac accaaacagt
    16141 catacaatag caggttccct tcaagggagt cagcgtacta aggtaaatga ctcaccctat
    16201 tgcactccaa cgctcaaggg tgggttattt tttgtctcta aaagatatga tcgacaacac
    16261 caaacttgca aatgctatca ttagcattat cgtttgaaat actgtcaaca taagcatcat
    16321 cccctttctt acggggtaac gctgaccacc cttgagttta cctatctatt gccattctat
    16381 tatactacaa aaaaggaacg tgcgttcgat atcgattgct atttttttaa gtttgtaatc
    16441 ctcgtccatt tcagtgtcct ctacctatta ccccattatt tcagccacaa gtttgtggga
    16501 gtatagtcgg gcgttgtgat cataaaccat tgtgctcacc attatctcat ctgccttcgt
    16561 ctcatctaag aaggattgca gcttttcctt tacgttgtta ggactcccaa tgattgtgga
    16621 gcttaattgt ttttctaaaa ttgccttttc atatgggctc atgagctcat ctaaattctc
    16681 taatggtggt tgtagctttg atggtgtgtt ccttatcatg tttaggaagc tttgtttgat
    16741 ggaactggct agcaattctg cttcctcatc cgtatctgcc gcaatgacgt ttactgctac
    16801 cattgcgtaa ggctctttat aatcctccga cggttggaag ttatcgtaat ataattttag
    16861 ggctggcagt gtgttttcag gtgaaaaatg actggcgaaa gcaaacggca tcccgagttg
    16921 tgctgataat cttgcactaa atccactaga acctaacaac caaataggga tattagctcc
    16981 ttcaccaggg attgctcgta ccggtccagt accttgaaaa taggcttgta gttgttctaa
    17041 ttgttccgga aaatcatcgc cattggtgta gtttgcccca cgaatagcat gagcagtttg
    17101 ttggtcagtt cccggtgcac gccctaatcc taaatcaatt cggcctggaa acatcgcttc
    17161 gagggttcca aattgctccg cgattaccag gggcgaatgg tttggaagca tgattccgcc
    17221 ggaacctacc cgaatagtag aagtatgtgc tgctacatgg ccgatgacga tagatgttgc
    17281 agagcttgct atgccaggca tattatggtg ctccgctaac cagtaccgtt tatagcctag
    17341 tttttccgtt aactgtgcta actctaccga atgttgaaag gattggccag gcgtccctcc
    17401 ttgcacaatg gatgcaagat caaggacgga aaaggatatg tcgttgatcg atttactcgg
    17461 tctatttatt gtcatgggat aacatcttct ttcatttaaa ttaatagttg gaattggcat
    17521 ggatgtgttt gtctagtatt gtgcgctttt catatagtaa ttcacaccag gattaaaaag
    17581 caacttgtaa gtatcagcat ataaaaaatg gttagagaca tatgtaacaa tatcaattcc
    17641 cgtttaaccg atttccaaat catcaagcat ggccatgaaa taagctaata acataaaata
    17701 aggggagaaa ttcctcttaa tattgaaata acacgaaaaa tagataaaat agacggaaag
    17761 gttccgccta ttttatggaa aaagaagaaa atggaccatt ttactttgct taaccggaaa
    17821 aactccgctt atatcaccca aaacgagttc cattcttgat ctaaacggaa taactccgtt
    17881 tatttaaatt cccttactaa ttaaggataa cctagaaggc ctcctttatt tatccctcac
    17941 atattcattt cttttcgaac atttagtttt acttcacata gttacaaagc gtacctatat
    18001 tctccacttc cactactact gtatctccag atttcattgg gcagctccct gaaggtgatc
    18061 ctgtagctag aacatcgcct ggctcaagtg tcatcacttg tgaaatccaa ctgataagat
    18121 aagggattga aagtgtcatt tgatttgtat tgccatcttg tactacattt ccatttaggg
    18181 ttgtaacaat tcttagattg gttgggtcga tgcctgtcac aatgtatgga cccaaaggac
    18241 caaatgtatc gaaacctttg cctcttgtaa actgaggatc tgatttagta aggtcccttg
    18301 cagtcacatc attaaaaatc gtacagccaa aaagataatc taatgcttct tcttctttta
    18361 tatttctgcc ccgttttcca atgattagtg ctacttcccc ctccagttct acctgttcgg
    18421 ttaaggtagt gggtggaagg atgatttcac cctgatccgg tatgatcgag gaggtaggtt
    18481 ttaaaaacag aaacggttca cgtagattgg ccgttcctcc agtctctttt gcgtgtccag
    18541 catatgtcca accaaaattg acaattttcg atggagatac tggttccaaa atctttactt
    18601 cattatattt aacccttact ccatcatagt ttatctcatt gttaacaatt tgtgtgaaat
    18661 cactagacaa ttgtacgata tcgtcaccat caataattcc ataatactct ttttcataac
    18721 gttgataacg aacgattgat tgtgtttttt gtaatgtctt catttatcta aaaacccctt
    18781 tacttatttt aaaactgttt acggtttaat ttatttttat cattatcttt agctatctct
    18841 aggtaaccat gactttgact attttcattt tcaggctttc taaaaagggg acaatttaaa
    18901 gattccttgc ctttatggag tgaaaaaagt attgagggat ccctcaatac tctttacaaa
    18961 aagcattaat gatcattgaa ttaaaatgtt tgttgaatct gcccttcccc ttgcttctgt
    19021 ttgacgtacc aaatacattt ccctgtatat ccataaataa tagctagggc aattgacaca
    19081 aagcttaacc acataaatgg aacataagca aaggtagaaa cacctagaat accagccata
    19141 aagattccgt tgtctgtcca aggaatcatc ccagaggtta atgttccccc aacttctgtg
    19201 tttcgtgcta atacccttcg atcgatgtgt aagttgtcat agctttctcc cataatttta
    19261 ggagttaata ttaatgaaac atacatagcg caaccaaata catttgcaaa aaatgccaca
    19321 attatagtgg atagtgttac atttccagct gatgttaaga aactatgaaa cttggaaatg
    19381 atcactttta gaactcctaa atgctcaaga agaccaccaa accctaaacc gaatatgatc
    19441 acagcaactg aaccaagcat accttctatt ccaccacggt tcagaagttt atccataaac
    19501 tcaactcctg tgttaataga aaaaccgtta taagcagtac caacagcatc ggggacattc
    19561 atgccttgga acactactgc ccagatggcc ccaagtagag ctccaatagc aatagaagga
    19621 acagaaggtt ttttcatagc tagcataaca ataacaaata tagcaggtgt taccatccaa
    19681 atttgaatat tgaatgtatc tagtaaagct agctttaaaa attctacttt ttctaaatct
    19741 gtgttattgc caccatatat aaatcctgct acagtaaaaa gaattgcggt aataagatag
    19801 gcagggatgt ctagatatag catggcacgt acgtgtgcaa taacttctac ctttgaaaga
    19861 gaagcagcaa gtacggtact gtcagaaagt ggagataatt tatcaccaaa gtatgctcct
    19921 gaaagaacgg ctcccgctac aagaggcaga ggcataccta atccttctcc aattgccatc
    19981 atcgcgattc cagctgttcc caccgttccc catgatgtac ctgtagctaa agaagtaatt
    20041 gagcagacaa ttaatgttgc taataagaaa atacttggat gaataaattc caatccataa
    20101 taaataagcg ttggtacgac tcctcctgca atccaagtcc cgataagagc accaactgca
    20161 acaagtatca atattgcctc aagtccgttt gaaattccgg ttgttatggc tttttgcagc
    20221 tcttcataac ggtatcctaa tttaaatcca agtaatatca caagaaacca cgaaataaac
    20281 agagctaact gtatgggtaa atcgaaaaag gcagtaaacg aaaaaacaat aacaagaaac
    20341 aaccctaatg tacaaacaat ttctaaaata gttggtaatc gtacactttt cacttctatt
    20401 cctccaataa caaattagta tgtatcttct aaaaatagat attttctcgt acgtaacccg
    20461 ttttcaagat gatgctagat gtgttgaaac cttatcatta ctctcgatca aaaagtgaga
    20521 ctcctgcaat tcctggattt gtcatttcgt aaggattcaa aatcaaatca agctcttcct
    20581 ctgttagcac atcatattga aggcacagct ctcttacaga tttacccttt aaaatagctt
    20641 ctctagcaat tcgtgagact acttcgtacc ctaagtgagg attaacagct gttataatac
    20701 caacactctt ttctacgtat tccctcattc tatcttcatt tgcttcaatg cctattaaac
    20761 agtaatctgt aaagcttcta aaaccattcc tcataatact gatagattgt aataagttaa
    20821 atacaaggat aggctccatt acatttaact ctaactgacc agcttcagaa gccagacaaa
    20881 ttgtatggtc attgcct
//
