LOCUS       NZ_CP095376            21095 bp    DNA     circular CON 06-NOV-2024
DEFINITION  Amycolatopsis sp. FBCC-B4732 chromosome, complete genome.
ACCESSION   NZ_CP095376
VERSION     NZ_CP095376.1
KEYWORDS    RefSeq.
SOURCE      Amycolatopsis sp. FBCC-B4732
  ORGANISM  Amycolatopsis sp. FBCC-B4732
            Bacteria; Bacillati; Actinomycetota; Actinomycetes;
            Pseudonocardiales; Pseudonocardiaceae; Amycolatopsis.
REFERENCE   1  (bases 1 to 10190959)
  AUTHORS   Choi,A.
  TITLE     Complete Genome Sequence of Amycolatopsis pretoriensis strain
            FBCC-B4732
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 10190959)
  AUTHORS   Choi,A.
  TITLE     Direct Submission
  JOURNAL   Submitted (07-APR-2022) Bioresources Collection & Research Team,
            Nakdonggang National Institute of Biological Resources, Donam 2-gil,
            Sangju-si, Gyeongsangbuk-do 37242, South Korea
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: HGAP v. 3.0
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 75.1x
            Sequencing Technology             :: PacBio RSII
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_023008405.1-RS_2024_11_06
            Annotation Date                   :: 11/06/2024 10:39:22
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.8
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 9,364
            CDSs (total)                      :: 9,298
            Genes (coding)                    :: 9,177
            CDSs (with protein)               :: 9,177
            Genes (RNA)                       :: 66
            rRNAs                             :: 4, 4, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 4, 4, 4 (5S, 16S, 23S)
            tRNAs                             :: 51
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 121
            CDSs (without protein)            :: 121
            Pseudo Genes (ambiguous residues) :: 0 of 121
            Pseudo Genes (frameshifted)       :: 50 of 121
            Pseudo Genes (incomplete)         :: 81 of 121
            Pseudo Genes (internal stop)      :: 14 of 121
            Pseudo Genes (multiple problems)  :: 19 of 121
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 05:14:56
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 4075557
            Orig. end                         :: 4096652
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP095376.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            Bacteria and source DNA available from NNIBR.
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..21095
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="RRE-containing"
                     /region_number="24"
                     /rules="minimum(1, [Bottromycin_Methyltransferase_RRE,
                     Cyanobactin_D_RRE, Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /tool="antismash"
     cand_cluster    1..21095
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /kind="single"
                     /product="RRE-containing"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..21095
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:11095](-)"
                     /cutoff="10000"
                     /detection_rule="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /neighbourhood="10000"
                     /product="RRE-containing"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..11095)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /neighbourhood="10000"
                     /product="RRE-containing"
                     /protocluster_number="1"
     gene            460..675
                     /locus_tag="MUY14_RS17700"
                     /old_locus_tag="MUY14_17700"
     CDS             460..675
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013226065.1"
                     /locus_tag="MUY14_RS17700"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MUY14_17700"
                     /product="hypothetical protein"
                     /protein_id="WP_247024104.1"
                     /transl_table=11
                     /translation="MAERRWHFIPTTAPLCWLYLGVGAVLLVSSILTLTRAETRAPILS
                     VIAAVAAVALVVTAAIGLARPRLRGR"
     gene            complement(677..943)
                     /locus_tag="MUY14_RS17705"
                     /old_locus_tag="MUY14_17705"
     CDS             complement(677..943)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="MUY14_RS17705"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="MUY14_17705"
                     /product="hypothetical protein"
                     /protein_id="WP_247024105.1"
                     /transl_table=11
                     /translation="MRIWWCGVVLSAVALLAACAGGGSGTGRLIPPTTSTTPVTSITPA
                     TDSPVTTTTPPATTQTRAHPPTATTTTKKTTTPRHTTTRRRPR"
     gene            complement(972..1562)
                     /locus_tag="MUY14_RS17710"
                     /old_locus_tag="MUY14_17710"
     CDS             complement(972..1562)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1148: hypothetical
                     protein"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013226062.1"
                     /locus_tag="MUY14_RS17710"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MUY14_17710"
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="WP_247025160.1"
                     /transl_table=11
                     /translation="MIDPVTLGRRLHELRGDRGLALKALAAAAGVSVSMLSAIERGEKT
                     PTVVVLSRIADGLGLSLSRLLAGLETDRVIVRRAAEQDHVAEPGGWHRTVLTPVIPGVN
                     FEWIRTTLPPRCDAGAFPAYAPGSHEFVAVESGTLCLGVGEADYVLNAGDSLYFPADAP
                     HSYANRGGEPCVYHVAALIMRPRENRTFGVSRV"
     gene            1581..2069
                     /locus_tag="MUY14_RS17715"
                     /old_locus_tag="MUY14_17715"
     CDS             1581..2069
                     /EC_number="2.3.-.-"
                     /GO_function="GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA]"
                     /GO_function="GO:0016746 - acyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020646968.1"
                     /locus_tag="MUY14_RS17715"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MUY14_17715"
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="WP_247025161.1"
                     /transl_table=11
                     /translation="MSTIAEVTEADAEGIAAVFAPYATDSVVTFETTPPTADQWRAKIR
                     ERAWPFLVLADEGEVLGYALAAPWRPKPAYRFSVETTIYLAPGATGRGHGRRLLGELLE
                     RCAEAGARQAIAVIVDSGSPASRTLHLAAGFTDAGVLRRVGFKHGRWLDTLLMQRDLG"
     gene            complement(<2088..3029)
                     /locus_tag="MUY14_RS17720"
                     /old_locus_tag="MUY14_17720"
                     /pseudo=""
     CDS             complement(<2088..3029)
                     /NRPS_PKS="Domain: PKS_ER (11-232). E-value: 8.4e-44.
                     Score: 141.9. Matches aSDomain:
                     nrpspksdomains_MUY14_RS17720_PKS_ER.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ADH_N"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ADH_zinc_N"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1028: crotonyl-CoA reductase / alcohol dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF024989.5"
                     /locus_tag="MUY14_RS17720"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /old_locus_tag="MUY14_17720"
                     /product="quinone oxidoreductase family protein"
                     /pseudo=""
                     /sec_met_domain="ADH_N (E-value: 6.8e-11, bitscore: 41.1,
                     seeds: 66, tool: rule-based-clusters)"
                     /sec_met_domain="ADH_zinc_N (E-value: 1.9e-20, bitscore:
                     72.3, seeds: 86, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MHAVFARDFGSPEVLTWTEFPDPVPGPGEVLVRLRAAGVNFMDTG
                     VRSGPVPTWSLPAVLGVEGAGTVTALGADVTGFAVGDRVAWYYHRGSYAEQIAIPARSL
                     VRLPGDIDDETAAAVMMQGLTANHFTTETYAIRPGDTAVVHAAAGGVGSVLTQLIKARG
                     GTVVGLVSRADKVSVAAEAGADHVLVSSGGGFEDRVKELTGGRGADVVYDGSGPEAFRS
                     SQLALRPHGVHAYYGVLIGNPVFRPMDLPNSILLSYPAVADHVPTREALLARTEELFGF
                     VRSGQLVPRIGQRYALADAARAHRDLESRRTTG"
     aSDomain        complement(2334..2996)
                     /aSDomain="PKS_ER"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_MUY14_RS17720_PKS_ER.1"
                     /evalue="8.40E-44"
                     /label="MUY14_RS17720_PKS_ER.1"
                     /locus_tag="MUY14_RS17720"
                     /protein_end="232"
                     /protein_start="11"
                     /score="141.9"
                     /tool="antismash"
                     /translation="PEVLTWTEFPDPVPGPGEVLVRLRAAGVNFMDTGVRSGPVPTWSL
                     PAVLGVEGAGTVTALGADVTGFAVGDRVAWYYHRGSYAEQIAIPARSLVRLPGDIDDET
                     AAAVMMQGLTANHFTTETYAIRPGDTAVVHAAAGGVGSVLTQLIKARGGTVVGLVSRAD
                     KVSVAAEAGADHVLVSSGGGFEDRVKELTGGRGADVVYDGSGPEAFRSSQLALRPHGV"
     CDS_motif       complement(2571..2612)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_MUY14_RS17720_0002"
                     /evalue="4.20E-03"
                     /label="PKSI-ER_m5"
                     /locus_tag="MUY14_RS17720"
                     /protein_end="153"
                     /protein_start="139"
                     /score="9.9"
                     /tool="antismash"
                     /translation="DTAVVHAAAGGVGS"
     CDS_motif       complement(2814..2852)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_MUY14_RS17720_0001"
                     /evalue="4.30E-03"
                     /label="PKSI-ER_m2"
                     /locus_tag="MUY14_RS17720"
                     /protein_end="72"
                     /protein_start="59"
                     /score="10.1"
                     /tool="antismash"
                     /translation="LGVEGAGTVTALG"
     misc_feature    complement(3087..3101)
                     /note="TFBS match to IolR, Regulator of the inositol
                     catabolism, confidence: medium, score: 19.9"
                     /tool="antismash"
     gene            complement(3108..3692)
                     /locus_tag="MUY14_RS17725"
                     /old_locus_tag="MUY14_17725"
     CDS             complement(3108..3692)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1148: hypothetical
                     protein"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004558438.1"
                     /locus_tag="MUY14_RS17725"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MUY14_17725"
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="WP_247024106.1"
                     /transl_table=11
                     /translation="MTDAITQALSEVGPRLKRVRTQRRVTLADLSTATGISKSTLSRLE
                     SGQRKPSLELLLPIAQAHQVPLDELVGAPEVGDPRVRLTARRIPRHNGAAMTVLPLTRQ
                     PGAPQAFKMILEPETGEPDPQVHEGYEWLYVLSGRLRLVLADRDMVLGPGEAAEFDTRL
                     PHWFGAVDRPAEILSLFGKQGERLHLRAKSR"
     gene            3770..4708
                     /locus_tag="MUY14_RS17730"
                     /old_locus_tag="MUY14_17730"
     CDS             3770..4708
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /GO_function="GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Pyr_redox_2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1176: alkyl hydroperoxide reductase subunit"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013226059.1"
                     /locus_tag="MUY14_RS17730"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MUY14_17730"
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="WP_247024107.1"
                     /sec_met_domain="Pyr_redox_2 (E-value: 3.6e-18, bitscore:
                     64.9, seeds: 64, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTENSYDVLVVGGGAAGLNAALMLGRARRRVAVVDAREPRNAPAE
                     HMHGFLSRDGLPPSDLLEIGREELAGYGVDLLEDSVTRLEPGFTARLASGRELTARRVL
                     VATGVHDDLPDLPGLRESWGTDAVTCPYCHGYEVRDEPLGVLGTEPASVEHALLVRQWS
                     PDVVYFAHIAPPSEEDRERLDARGIRVVDGVVTAVRREAGRLTGIELGDRFVARTALFL
                     RTRTVPHDELLRGLGYTEGAVDPSGKTSVPGVWAAGNVVDARATVIIAAAQGAAAAGAL
                     NHDLVTEDVDRAVAAYGGFSPAAERAAAGAR"
     gene            4741..5196
                     /locus_tag="MUY14_RS17735"
                     /old_locus_tag="MUY14_17735"
     CDS             4741..5196
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013226058.1"
                     /locus_tag="MUY14_RS17735"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MUY14_17735"
                     /product="oxidoreductase"
                     /protein_id="WP_247024108.1"
                     /transl_table=11
                     /translation="MRPTLYEFAGGDPAFLALAAAHHERCLADPELNHPFSHPGQHPRH
                     VERLAHYWAEVMGGPPRFSQECSDHSAMLRMHAGNGDMSDLGRRFVSCFVQAADDAALP
                     ADPEFRAALRAYMEWAVAEVLTYPGPATDVPAGLAMPHWSWNGLQTL"
     gene            5359..5949
                     /locus_tag="MUY14_RS17740"
                     /old_locus_tag="MUY14_17740"
     CDS             5359..5949
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003082526.1"
                     /locus_tag="MUY14_RS17740"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MUY14_17740"
                     /product="TIGR03086 family metal-binding protein"
                     /protein_id="WP_247024109.1"
                     /transl_table=11
                     /translation="MLLDRFLLASKGFEHHLRAVPSAAWGAPTPCSEWDVRALVNHMTR
                     GNLNYVGLLAGATREEFLAARDADALGDDPVTAFTESVRVCAEAFAAPDALDRVVDYPL
                     GELTGRRALAVRTTDSTVHTWDLARALGADETLDPGLVAWIDEEHEAIFAGLALNSRVF
                     AEPPPDEPGASRQDRVLRRFGRDPRSPASRPAR"
     gene            complement(5897..6796)
                     /locus_tag="MUY14_RS17745"
                     /old_locus_tag="MUY14_17745"
     CDS             complement(5897..6796)
                     /GO_function="GO:0070403 - NAD+ binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003082528.1"
                     /locus_tag="MUY14_RS17745"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MUY14_17745"
                     /product="NAD-dependent protein deacetylase"
                     /protein_id="WP_247024110.1"
                     /transl_table=11
                     /translation="MRTRPTLSWTSADAPLPRTSSLDELTDVVARGRVAVLSGAGLSTE
                     SGIPDYRGETGSLRRHTPMTYDEFVTSAEGRQRYWARSHLGWRTIARADPNDGHRAVTA
                     LCEGGFVGGVITQNVDGLHQAAGTADAIELHGSLDRVICLDCRRTSPRADLDRRLRAAN
                     PAFDGAATRINPDGDVELPEDVVRRFTTVACADCASGVLKPDVVFFGENVPRPRVEECY
                     RLVDDAGALLVLGSSLTVMSGLRFVRHAAKAGKPVVIVNHGETRGDRYASVRVDRPLGG
                     ALTELAARLGCEDRGRTA"
     gene            complement(6796..7698)
                     /locus_tag="MUY14_RS17750"
                     /old_locus_tag="MUY14_17750"
     CDS             complement(6796..7698)
                     /GO_function="GO:0016747 - acyltransferase activity,
                     transferring groups other than amino-acyl groups [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1135: MarR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020646963.1"
                     /locus_tag="MUY14_RS17750"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MUY14_17750"
                     /product="MarR family winged helix-turn-helix
                     transcriptional regulator"
                     /protein_id="WP_247024111.1"
                     /transl_table=11
                     /translation="MDRDLIDGVRRFNRTVTQRIGALDDAFLARDRPLGQARVLWEIGV
                     AGLDVRELRERLDLDSGYLSRLLRGLEQDGLVRVEPSDADGRVRTARLTDAGVAERATL
                     DRLSDDAAASILGPLSGGQRRRLVAAMAEVERLLTASAVEVAPCAPERPAARFCLRAYF
                     AELAERFDDGFDPELSSSAADAEMTPPSGVLLVAALHGEPVGCGALKFRGGAPAEVKRM
                     WVAPSARGLGLGRRLLAELEAHAAAQGVRTLRLETNRALAEAVGLYLAAGYREVAPFND
                     ERYADHWFEKHLAAPRTLG"
     misc_feature    complement(7801..7816)
                     /note="TFBS match to LexA_variant_1, Repressor of DNA
                     damage response, confidence: weak, score: 20.02"
                     /tool="antismash"
     gene            7845..9998
                     /locus_tag="MUY14_RS17755"
                     /old_locus_tag="MUY14_17755"
     CDS             7845..9998
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1041:
                     transcriptional regulator, SARP family"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: protein motif:HMM:NF013124.5"
                     /locus_tag="MUY14_RS17755"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MUY14_17755"
                     /product="tetratricopeptide repeat protein"
                     /protein_id="WP_247024112.1"
                     /transl_table=11
                     /translation="MVDEPEHEHGTRSVTNALPGTVTGSVVQAGTIRQVVFAAATQQAL
                     PVPRQLPPAVRDFAGRGDQLARLDELLLSHDEGRPGGVVISALDGTAGVGKTALAVQWA
                     HRVEHHFTDGTLFADLRGYGPSAPVRPDLVLASFLHVLGIAEDRIPADLDAQVSVYRSV
                     LAGRRVLILLDNAGTAEQVRPLLPGSPGCAVLVTSRASLTGLLVAEAASQLTLDLFTAD
                     EAHVLLRRILGRERVSAEPAAVADLVEVCARLPLALRIAATRIATRRHTSVAEVVADIV
                     GDRTGLDVLSSSGDERSAVRSVFDWSYTRLVDEHAVLFRRLGLHPGTEFGVPAAAAVAG
                     IDAATAYRHLEALADVHLIESVGGRRYRCHDLLHAYAAHRAERDDSPDSRRDATARLFS
                     WYAHTAQAADKLVFPGLESPAADLAPDGPEVPLTDRAGALAWLNTEQANLLAVLRSAPE
                     HPTAVVLAGATRFLSLGPRAVWPVRLEAETLGLRAAEAAGNRTAEALLLGFRGDTLATL
                     ERWDDAEADFTRQLALARELGDAVRQRVGLIGLGQVRFLQRRYPEARDYYRQALPLARQ
                     AGGGRPEAVVECNLSRIAVRLGEFGQAREHAERELVLRRRSADRVGEAYALRDVAVALH
                     GLEDHDTAIEYANQAVALYRTLAGTEVFLAEALETAAASLERTGNLTRAAEHLGEACEL
                     LDELDPERAGTLRERIRELSSRG"
     gene            complement(10001..11095)
                     /locus_tag="MUY14_RS17760"
                     /old_locus_tag="MUY14_17760"
     CDS             complement(10001..11095)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RRE-containing: Pantocin_Microcin_RRE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ThiF"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015099603.1"
                     /locus_tag="MUY14_RS17760"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MUY14_17760"
                     /product="ThiF family adenylyltransferase"
                     /protein_id="WP_247024113.1"
                     /sec_met_domain="Pantocin_Microcin_RRE (E-value: 4.8e-19,
                     bitscore: 67.4, seeds: 9, tool: rule-based-clusters)"
                     /sec_met_domain="ThiF (E-value: 4.6e-43, bitscore: 146.4,
                     seeds: 54, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRRPMIKPEHLPVRHGGNRVRIGGVVRGIAADIADPDGWVWALLE
                     LLDGSRTTGQVVADLARLHPTRAGTDVRAAIDDLIRAGYVEDAGEPAPGRLTAAERERY
                     GRSKALFRWMDRAPRRTSWDTQLLLSGARVVVIGIGGVGCTAAQALVRSGVGHVHCVEP
                     DVVELSNLNRQVLFTERDLGRPKVDVAVDRLREQNSEVRVTGTRLAVDGPAVLRTLATG
                     FDVVLLAADQPEEIRSWTNQACEATGTAWVHGGYHGPQVGCGLYRPGAGPCYDCARVAE
                     RERRAGLPPRTYSAASGRAARTHAANAVSAGVAGQLAAHATLSLITGAPALRTNCQYGF
                     NLVTLQDSFAIGPDAPRPDCPTCA"
     aSDomain        complement(10826..11095)
                     /aSDomain="Pantocin_Microcin_RRE"
                     /aSTool="RREfinder"
                     /database="RREFam.hmm"
                     /description="RRE-containing E1-like protein in a
                     pantocin/microcin cluster"
                     /detection="hmmscan"
                     /domain_id="rrefinder_MUY14_RS17760_Pantocin_Microcin_RRE.1
                     "
                     /evalue="1.40E-21"
                     /identifier="RREFam017.1"
                     /label="MUY14_RS17760"
                     /locus_tag="MUY14_RS17760"
                     /protein_end="90"
                     /protein_start="0"
                     /score="67.4"
                     /tool="antismash"
                     /translation="MRRPMIKPEHLPVRHGGNRVRIGGVVRGIAADIADPDGWVWALLE
                     LLDGSRTTGQVVADLARLHPTRAGTDVRAAIDDLIRAGYVEDAGE"
     gene            11343..14513
                     /locus_tag="MUY14_RS17765"
                     /old_locus_tag="MUY14_17765"
     CDS             11343..14513
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1041:
                     transcriptional regulator, SARP family"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: protein motif:HMM:NF013124.5"
                     /locus_tag="MUY14_RS17765"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MUY14_17765"
                     /product="tetratricopeptide repeat protein"
                     /protein_id="WP_247024114.1"
                     /transl_table=11
                     /translation="MRDTEPANVTNQCQHRSGRWRGRASRCETRNGRGSSAIPGGGKAG
                     GMEIVFGILGPTAMRMHGRLHADWGSPKLHKVLAALLTNPKVRVGMTGLAEWVWSVDEP
                     EPNDPISTFRTYAARIGKVMRDADVPATIRTVDGALHLDVERTAIDYFAFEALIETARR
                     HSKENDHEAACEVAATALGLWRGEPLADLTSQPARDWRYSAVHNAWLPANQLLLGELIA
                     VGRFDAALRKIDELQREHPTDIGLARRRLRVLRELDRTDDMGAYHIAVRKLLLAGDDQA
                     AAADLLKYYNTLIAGKPAPPARPGARSAAERLAALPRPRPPSDPPPSLLPALAPRGRST
                     LPPAATDFVGHHDIRQTLDELARTAEGRFSPGVIVLDGLAGIGKTALAVHWAHGQYGRL
                     ADTALYLDLHGFDGGRPVTADDVVDELLDAFEVPISRLATRARRDAKLREILAQSRTLV
                     VLDNAANSAHVLPLLFTLSPCLLLVTSRKGLTALTSRHGARRCSVTPLNEQHAAQVLTN
                     RIGPRGAAEQEPLARIAALCGGVPLALQLVAHHIEGRRGAALSEFADELQDQSRLLDIG
                     DDGDDPPATMRAALLVTYNGLPRAARDLLWLIGLSPAPELTPHAAAALAGKPVKEVQHA
                     LDVLVSTHFLTHTGKRDRYRVHDLLRTFARELAEAEQYAGVRAEAERRLLSFCLHTSYA
                     ADRLLFPFRPPVPMLPAAADTPMVEFPSENAAAAWLSNEKANFVRIIPWAAQRNHHDYA
                     WRIPHNLYGLYRRYGFYNELRDAFTVSVSSAQAVADPESEAATRSDFGMILLALGDPGP
                     ALLEFHLAAAIAQQTNSAIGIATSFLHLGTHKAQAGEFEAAEALYQRALDRLEAADSAG
                     TESAIHHRLADTLRHRGRHDEALARYRHALDLRESIGNRHGQAETLAEMASTLCEQRKY
                     GEALDHGLRALRIVEQINDLEVGPRACCVVATVSYRQADHAAAIGYARQAVRLAARTHN
                     AVVESDALHVLGHALHETGRLAAAEEGWTNAAAIYADLGNHERERHVREDLATLSTASA
                     NGTFSPET"
     gene            14748..14876
                     /locus_tag="MUY14_RS46925"
     CDS             14748..14876
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="MUY14_RS46925"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_281506313.1"
                     /transl_table=11
                     /translation="MKKLLAGLALASALVLTGAGATGLQYWNPEKITSLETVSAIA"
     gene            15034..16485
                     /locus_tag="MUY14_RS17770"
                     /old_locus_tag="MUY14_17770"
     CDS             15034..16485
                     /EC_number="2.7.11.1"
                     /GO_function="GO:0004674 - protein serine/threonine kinase
                     activity [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_process="GO:0006468 - protein phosphorylation [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Pkinase"
                     /gene_functions="regulatory (smcogs) SMCOG1030:
                     serine/threonine protein kinase"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009947969.1"
                     /locus_tag="MUY14_RS17770"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MUY14_17770"
                     /product="serine/threonine-protein kinase"
                     /protein_id="WP_247024115.1"
                     /sec_met_domain="Pkinase (E-value: 2.2e-45, bitscore:
                     154.1, seeds: 54, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSWQFGPYRVESLIARGGMGEVYRAHDTRHDRVVALKLLAPEFAA
                     DRDFQERFRREAHAVARLREPHVIPIHAYGEHDGRLYLDMRLVDGDDLGSRLAAGGAPS
                     PADAVDVIGQVARALAAAHAEGLVHRDVKPSNVLVDATGFAYLVDFGIARAAGAATGLT
                     ATGGAVGTLDYMAPERFADAPADHRVDVYSLACVLHQCLTGSKPFPVTTAASLIGAHLH
                     QPPPRPSALRPGLPAAFDEVIARGMAKNPADRFGSVEELAGAARAALGGTSPVRAAAPP
                     TRQATRVTPAPVSEPPRTSKAPWVVAAVALLALVAVAGWFTILRPALQDRPTAGPASTS
                     PPATTTPSPTPPPAAAPVTTTQVSVRTSVATTVAAGGADLGLATTMSTPACDGSFVVVL
                     GSAVTPARYRADVQRFLDLHPGASYLHAPTTGCGSLRQQVNGADVYAVYAGPFAAKETA
                     CARRSGGAYVKRLDDTSAPTQVISC"
     gene            complement(16475..17188)
                     /locus_tag="MUY14_RS17775"
                     /old_locus_tag="MUY14_17775"
     CDS             complement(16475..17188)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="MUY14_RS17775"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="MUY14_17775"
                     /product="hypothetical protein"
                     /protein_id="WP_247024116.1"
                     /transl_table=11
                     /translation="MLEWLLDPAGPLEGRGHVHLTDKTYFAVRAAVELLAGPGTAAAAR
                     TLHRAGPAAFGAARWEFFLTAFTSVLRLNPRRGVQTSPERFFALVDDLAATPGEAGEIV
                     ALFRGGGERVAAYRARLAGDPGLVGVLDPLVPAVVHTVRHWSAGGTPVALVHDEQLALT
                     PERVLQLKATLGHRLAGVRFVDSRADARVQIADFLAGVARRIASDELNHRGDARLTGLL
                     KSFVDTNSVWDGLSS"
     gene            complement(17128..17388)
                     /locus_tag="MUY14_RS17780"
                     /old_locus_tag="MUY14_17780"
     CDS             complement(17128..17388)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="MUY14_RS17780"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="MUY14_17780"
                     /product="hypothetical protein"
                     /protein_id="WP_247024117.1"
                     /transl_table=11
                     /translation="MSPVEIACDESGSEGENLLGGETDVFAHAGVRLSPEAAAACVREI
                     RARIGSPAEEYKASCCAASTARCSSGCSTPPVRSRAAATCT"
     gene            complement(17448..17876)
                     /locus_tag="MUY14_RS17785"
                     /old_locus_tag="MUY14_17785"
     CDS             complement(17448..17876)
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /GO_function="GO:0051537 - 2 iron, 2 sulfur cluster binding
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020638930.1"
                     /locus_tag="MUY14_RS17785"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MUY14_17785"
                     /product="Rieske (2Fe-2S) protein"
                     /protein_id="WP_247024118.1"
                     /transl_table=11
                     /translation="MRDDETDPVLARRTALAVLGAGLAAGCSTYGGSQAPPPAAQQPPA
                     AGGTELGPAADIPVGGGKVFADKQVVVTQPAAGTFAAFSAVCTHQGCTVDAVADGTINC
                     PCHGSKFKIADGSVANGPASQPLPKKAVTVTGGKVTLA"
     gene            complement(17889..18431)
                     /locus_tag="MUY14_RS17790"
                     /old_locus_tag="MUY14_17790"
     CDS             complement(17889..18431)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020638929.1"
                     /locus_tag="MUY14_RS17790"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MUY14_17790"
                     /product="DUF6529 family protein"
                     /protein_id="WP_247024119.1"
                     /transl_table=11
                     /translation="MTTAGHRTAVTLLVPLFAGAVVSVVLGVYGSLHTPTGVAVNVAGF
                     SSPQGVKAWLATVVVVLVLVQLLSALSLYGKLGATPAWMGTVHRWSGRVAFLVSIPVAL
                     HCLYALGFQSFDTRVLLHSLLGCFFYGAFVAKMLLLRKDGAPAWALPVLGGLVFTGLVG
                     LWLSASLWFFTQSGLTF"
     gene            complement(18431..19099)
                     /locus_tag="MUY14_RS17795"
                     /old_locus_tag="MUY14_17795"
     CDS             complement(18431..19099)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013226052.1"
                     /locus_tag="MUY14_RS17795"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MUY14_17795"
                     /product="hypothetical protein"
                     /protein_id="WP_247024120.1"
                     /transl_table=11
                     /translation="MKHPGPLFTLLAGVALAGGIGIVNLATGTGAAPVAGAASAAGSTT
                     AVPPPRTTTSEAPKPEAPARADYAGRVTGGGASVAVSVRDGHAIAYLCDGKKVEAWLQG
                     VTTGGKLDLKGAKNAALSGSFDATAATGTVTASGKTWQFTAPTAKKPAGLYRAAPKVKG
                     QQAKAGWIVLPDGSQVGILAAGDDATAAPPLDPAAGTASVDGAPVTAEPISGLAGNGDF
                     "
     gene            19233..20255
                     /locus_tag="MUY14_RS17800"
                     /old_locus_tag="MUY14_17800"
     CDS             19233..20255
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1104: putative esterase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020646961.1"
                     /locus_tag="MUY14_RS17800"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MUY14_17800"
                     /product="esterase family protein"
                     /protein_id="WP_247024121.1"
                     /transl_table=11
                     /translation="MLPWEGDLAGRLDRHTLESELLRGNPLGDPHERPLWVYVPPGYDD
                     GDERYPAVYVIQGYTGHVAMWANRTPFRQTFLETADAVFAGGAPGCVVVYVDAWTAYGG
                     SQFVDSPGTGRYHSYLCDEVVPWVDAHYRTVPAAGSRAIAGKSSGGFGAMITPMLRPDL
                     FGALATHAGDSLYELSYIQDFGKAARALRGYDQDIAKWWADFRSRPAFTKPEDATLLQL
                     LGVSACFSAREDGTPELPCDPLTGAVRPEVWERWLAWDPVRMVPDHAAAIRSLRAVWID
                     AGTSDEYYLDLGAEAFRAAIAAAGLPAERVHFELFDAGHAAIDYRYPLSLAWLAGRLAR
                     "
ORIGIN
        1 atgacgaggc cgacgaggaa ccgcgcgacg agcagaaccc agtacgcggg cgcggccgcg
       61 gcgaggaagc cggcgacggc gagcaggagc atcaacgcgg ccaggaccgg ccgccggtcg
      121 gcgcggccga tcgcgacggt caccaccggc gcggcgatcg cgccgacgag gccgggcacg
      181 gtcatcgtcc agcccgcggt gcccgccgaa acgccgaacg tggccgcgat cggcgtcagc
      241 agcccgatcg gcaggatttc ggtggtgacg atggcgaaga tgccgacggt cacagctgtg
      301 acagcaggcc agcgggatgc gttcatgcgc ccagtagatc gacgtcgccg cgcccgggct
      361 ggcaggtttg cgacagctcg gggtcatggc ggattcccgc cggtttgatc gtcacctgat
      421 cggggcaaat ccggggtgaa ggtcgatcaa ggaggttcga tggccgaacg gcgttggcac
      481 ttcatcccga ccaccgcccc gttgtgctgg ctctacctgg gcgtgggcgc ggtcctgctc
      541 gtctccagca tcctcacgct gacgagagcg gaaacccgcg ctcccatcct gtcggtgatc
      601 gcggcggtgg cggccgtcgc gttggtcgtc acggccgcga tcggcctggc gcggccccgc
      661 ctgcgcgggc gctgactcag cgcggccgcc gccgcgtcgt cgtgtgacgc ggggtggtcg
      721 tcttcttggt ggtcgtcgtc gccgtcggcg gatgcgctct cgtctgcgtg gtcgccggcg
      781 gcgtcgtggt cgtcaccggg gagtccgtgg ccggtgtgat cgaagtgacc ggcgtcgtcg
      841 aggtggtggg tgggatcagc cgcccggtgc ccgatccgcc gccggcgcac gcggcgagca
      901 gcgcaaccgc actcaggacg acgccgcacc accagatccg caccacccgg acgttaacag
      961 cgcggcgggc gtcagacccg cgaaacgccg aaagtccggt tctcacgcgg ccgcatgatc
     1021 agcgccgcga cgtggtacac gcagggttct ccgccgcggt tcgcgtacga atgcggtgcg
     1081 tcggcgggga agtagagcga gtcgcccgcg ttcaggacgt agtccgcctc gccgacgccg
     1141 aggcagagcg tgcccgactc gacggcgacg aactcgtggg accccggggc gtaggcgggg
     1201 aacgcgcccg cgtcgcagcg cggcggcagg gtcgtgcgga tccattcgaa gttgacgccg
     1261 gggatcaccg gggtcagcac cgtgcggtgc cagccgcccg gctcggcgac gtggtcctgc
     1321 tcggcggcgc ggcggacgat cacccggtcc gtctcgaggc cggccagcag gcgggacagc
     1381 gacaggccga gcccgtcggc gatccgcgac agcacgacga ccgtcggcgt cttctccccg
     1441 cgttcgatgg ccgacagcat gctgacgctc acgcccgccg ccgcggccag ggccttcagc
     1501 gcgagcccgc ggtcgccgcg cagctcgtgc agacggcggc cgagcgtcac cggatcgatc
     1561 attcctctat gatagcgacc atgtccacta tagcggaagt gacggaggcc gacgccgaag
     1621 gcatcgccgc cgtcttcgcg ccgtacgcca cggactccgt cgtgacgttc gagaccacgc
     1681 cgccgaccgc ggaccagtgg cgcgcgaaga tccgcgagcg cgcctggccc ttcctcgtcc
     1741 tcgccgacga aggcgaagtc ctcgggtacg cgctggcggc gccgtggcgc ccgaagccgg
     1801 cgtaccggtt ctccgtcgag acgacgatct acctcgcccc gggcgccacc ggccggggcc
     1861 acggccgccg gctgctcggc gaactgctgg agcggtgcgc cgaagccggg gcgcggcagg
     1921 cgatcgcggt gatcgtcgac tccggcagcc cggcctcgcg caccctccac ctcgcggccg
     1981 gcttcaccga cgcgggcgtg ctgcggcgcg tcgggttcaa gcacggccgc tggctcgaca
     2041 cgctgctgat gcagcgggac ctgggctgac gggagcagca gcagctttcc cgtcgtgcgc
     2101 cgggattcca ggtcccggtg ggcccgcgcg gcgtcggcga gggcgtagcg ctgcccgatg
     2161 cggggcacga gctgtccact gcggacgaag ccgaagagct cctcggtccg cgccaggagg
     2221 gcttcccgcg tcggcacgtg atcggcgacc gccggatagg acagcaggat gctgttcggc
     2281 aggtccatcg gccggaacac cgggttgccg atcagcacgc cgtagtaggc gtgcacgccg
     2341 tgcgggcgca gggcgagctg cgacgagcgg aacgcctccg gcccgctgcc gtcgtagacg
     2401 acgtcggcac cgcgaccgcc ggtgagctcc ttcacgcggt cttcgaaacc gccgccgctc
     2461 gacacgagca cgtggtcggc accggcttcc gccgccaccg agaccttgtc cgcccgggac
     2521 accaggccga ccaccgtgcc gccgcgcgcc ttgatcagct gggtcagcac cgacccgacc
     2581 ccgcccgccg cggcgtgcac gaccgccgtg tcccccggcc ggatcgcgta cgtctcggtg
     2641 gtgaagtggt tggcggtcag gccctgcatc atgacggcgg cggcggtctc gtcgtcgatg
     2701 tcgccgggga ggcgcacaag cgatcgcgcc gggatggcaa tctgctcggc gtagctgccg
     2761 cggtggtagt accaggcgac gcggtcgccg acggcgaacc cggtcacgtc cgcgcccagc
     2821 gcggtcaccg tgccggcgcc ttcgaccccc agcacggccg gcagggacca cgtcggcacc
     2881 ggcccgctcc ggacgccggt gtccatgaag ttcaccccgg ccgcgcggag ccggacgagg
     2941 acctcgcccg ggccgggcac ggggtcgggg aactccgtcc aggtcaagac ctccggactg
     3001 ccgaagtcac gggcgaacac cgcgtgcatc gcggaacctt ctctctcggc cgggagcggg
     3061 acaccgccac tcaacgccga gtgaaatgga ccggcaagtc cagaaagtca gcgggacttc
     3121 gcccgcaggt gcagccgctc cccctgcttg ccgaacaggc tgaggatctc cgccggccgg
     3181 tcgaccgcgc cgaaccagtg cggcaggcgc gtgtcgaact ccgccgcctc gcccgggccc
     3241 aggaccatgt cgcggtcggc cagcaccagc cgcaaccgtc ccgaaaggac gtacagccac
     3301 tcgtagccct cgtggacctg gggatcgggc tcgcccgtct ccggttccag gatcatcttg
     3361 aacgcctggg gggcgccggg ctggcgggtc agcggcagga cggtcatcgc cgcgccgttg
     3421 tggcgcggga tgcggcgggc ggtcaggcgg acgcgggggt cgccgacctc cggggcgccc
     3481 accagctcgt cgagggggac ctggtgggcc tgcgcgatcg gcagcagcag ttccaggctc
     3541 ggcttgcgct ggccggactc caagcgcgac aacgtgctct tcgaaatgcc cgtcgccgtc
     3601 gagaggtcgg ccagggtgac ccgccgctgg gtgcggaccc gcttgagccg gggaccgacc
     3661 tcggacaggg cctgggtgat cgcgtccgtc atgcctccag gaaaccccct tgtcccggaa
     3721 acggcaacaa tagttgtcgg atccgcgaag ccgggttcag ggtggcgtca tgaccgaaaa
     3781 cagctatgac gtcctggtgg tgggtggcgg ggccgccggc ctcaacgccg ccctgatgct
     3841 gggccgcgcg cggcggcggg tcgccgtcgt cgacgcccgg gaaccgcgca acgccccggc
     3901 cgagcacatg cacggcttcc tttcccgcga cggcctgccg ccgtccgacc tgctcgagat
     3961 cgggcgcgag gagctcgccg gctacggcgt cgacctgctc gaagacagcg tgacgcggct
     4021 cgagcccggc ttcaccgccc ggctcgcgag cgggcgggag ctgaccgccc ggcgggtcct
     4081 ggtcgccacc ggcgtccacg acgacctgcc ggacctgccc gggctgcggg agagctgggg
     4141 caccgacgcg gtgacctgcc cctactgcca cggctacgag gtgcgcgacg agccgctcgg
     4201 cgtcctcggg accgaacccg cgagcgtcga gcacgcgttg ctggtgcgcc agtggtcccc
     4261 cgacgtcgtc tacttcgcgc acatcgcacc accgtccgaa gaggaccgcg agcggctcga
     4321 cgcgcgcggg atccgcgtcg tcgacggcgt cgtcaccgcg gtgcggcggg aagccgggcg
     4381 gctcaccggg atcgagctcg gcgaccggtt cgtcgcgcgg acggcgttgt tcctgcgcac
     4441 ccggaccgtc ccgcacgacg agctcctgcg cgggctcggc tacaccgaag gcgcggtcga
     4501 ccccagcggg aagaccagcg tgccgggggt gtgggcggcc gggaacgtcg tcgacgcgcg
     4561 ggcgaccgtg atcatcgccg cggcccaggg cgcggccgcc gcgggtgcgc tcaaccacga
     4621 cctcgtcacc gaggacgtcg accgggcggt cgcggcgtac ggtggcttct cccccgccgc
     4681 cgaacgcgcc gccgccggcg cgcgctagct tccgggggcg cggcgtgcca ggctcggcgg
     4741 gtgcgcccca cgctctacga attcgccggc ggtgaccccg cgttcctcgc gctggccgcc
     4801 gcccaccacg agcgctgcct cgccgacccg gagctgaacc acccgttctc gcaccccggg
     4861 cagcacccgc ggcacgtcga acggctggct cactactggg ccgaggtcat gggcggccca
     4921 ccgcggtttt cgcaggagtg cagcgaccac tccgcgatgc tgcggatgca cgccggcaac
     4981 ggcgacatga gcgacctcgg ccgccggttc gtgagctgct tcgtgcaggc ggcggacgac
     5041 gcggctctgc ccgccgaccc cgagttccgc gccgcgctgc gggcctacat ggagtgggcg
     5101 gtggcggagg tgctgaccta ccccggcccc gccaccgacg tccccgccgg gctcgccatg
     5161 ccgcactggt cctggaacgg gttgcaaacg ctgtaacgca gtgggtggcc gccgcgtctt
     5221 gcaggcgacg accggctgtg gaggtccgtc gccagagccc ggtccgggcg ggttcccccc
     5281 acccacccgg accgggctcg tccacgacgt ccgatacccg cgagcgcttg gcccgggggc
     5341 cgggccagac tggcagccat gctcctggac cggttcctgc tcgccagcaa gggtttcgag
     5401 caccacctcc gcgcggtgcc gtccgccgcc tggggcgcgc cgacgccgtg ctccgagtgg
     5461 gacgtgcgcg cgctggtcaa ccacatgacc cgcggcaacc tcaactacgt cgggctcctc
     5521 gccggcgcca cgcgcgagga gttcctggcc gcccgcgacg ccgacgcgct cggcgacgac
     5581 cccgtcaccg cgttcaccga gtcggtgcgg gtgtgcgccg aagcgttcgc cgcgccggac
     5641 gcgctggacc gggtcgtcga ctacccgctg ggcgagctga ccgggcggcg ggcgctggcc
     5701 gtccggacga ccgacagcac cgtgcacacc tgggacctgg cccgcgcgct cggcgccgac
     5761 gagaccctcg atccggggct cgtcgcgtgg atcgacgagg agcacgaggc catcttcgcg
     5821 gggctggcgc tgaactcgcg ggtgttcgcc gagccgccgc cggacgagcc cggtgcgtcg
     5881 cggcaggacc gggtgctcag gcggttcggc cgcgatcctc gcagcccagc ctcgcggcca
     5941 gctcggtgag cgccccgccg agcggccggt cgacccgcac cgacgcgtag cggtctccgc
     6001 gcgtttcgcc gtggttgacg atcaccaccg gcttgcccgc cttcgccgcg tggcggacga
     6061 accggaggcc ggacatcacc gtgagggacg aacccagcac caacagcgct ccggcgtcgt
     6121 cgacgagccg gtagcactcc tcgacgcgcg ggcgcgggac gttctcgccg aagaacacga
     6181 cgtccggttt cagcacgccg gacgcgcagt ccgcgcacgc gacggtggtg aaccggcgga
     6241 cgacgtcttc cggcagttcg acgtcgccgt ccgggttgat gcgggtggcc gcgccgtcga
     6301 aggcggggtt cgccgcgcgc aggcggcggt cgaggtccgc gcgcgggctc gtgcggcggc
     6361 agtccaggca gatcacgcgg tcgaggctgc cgtgcagctc gatcgcgtcg gcggtgcccg
     6421 cggcctggtg caggccgtcg acgttctgcg tgatgacgcc gccgacgaac ccgccttcgc
     6481 acagcgcggt caccgcgcgg tggccgtcgt tggggtcggc gcgggcgatc gtgcgccagc
     6541 cgaggtggct gcgcgcccag taccgctgcc gcccctcggc gctggtgacg aactcgtcgt
     6601 aggtcatcgg cgtgtgccgg cgcagactgc cggtctcgcc gcggtagtcg gggatgccgg
     6661 actcggtgga cagcccggcg ccgctcagca cggcgacgcg gccgcgcgcg acgacgtcgg
     6721 tgagctcgtc gaggctggac gtccgcggca gcggcgcgtc cgccgaggtc caggagaggg
     6781 tgggccgggt ccgcactaac ccagggtacg gggagcggcg aggtgcttct cgaaccagtg
     6841 atcggcgtag cgctcgtcgt tgaacggcgc gacctcgcgg tagccggccg cgaggtagag
     6901 cccgaccgcc tcggcgagcg cgcggttcgt ctccagccgc agcgtccgga ccccctgcgc
     6961 ggcggcgtgc gcctccagct cggcgagcag ccggcggccc agcccgagcc cgcgcgcgga
     7021 cggcgccacc cacatccgct tgacctcggc gggcgcgcca ccgcggaact tgagcgcccc
     7081 gcacccgacc ggctccccgt gcagcgcggc gacgagcagc accccggacg gcggcgtcat
     7141 ctcggcgtcg gcggcggagc tgctgagctc cgggtcgaaa ccgtcgtcga accgctcggc
     7201 cagctcggcg aagtaggcgc gcaggcagaa ccgggcggcc ggccgctccg gcgcacacgg
     7261 cgcgacctcg acggccgacg cggtcagcaa ccgctcgacc tcggccatcg cggcgacgag
     7321 ccggcggcgc tgcccaccgg acagcggccc gaggatcgac gcggccgcgt cgtcggagag
     7381 ccggtcgagg gtggcgcgct cggccacccc ggcatcggtg agccgcgcgg tccgcacgcg
     7441 cccgtcggcg tcactcggct cgacgcgcac gaggccgtcc tgctcgagcc cgcgcaggag
     7501 ccggctgagg tagccggagt cgaggtccag ccgttcccgc agctcccgca cgtccagccc
     7561 ggcgacgccg atctcccaga ggacgcgcgc ctgcccgagc ggccggtcgc gggcgaggaa
     7621 ggcgtcatcg agcgcaccga tccgctgggt gaccgtgcgg ttgaaccgcc ggacgccgtc
     7681 gatgaggtcc cggtccattc gctgactata gtcagcgaaa tttgccgaac accatccgca
     7741 tccgggtgac ggtcggtgtc gaccgcttca cattccgctc accggcccgc tgttgtgcgg
     7801 tagaccggaa gttcgactgg tgggtggcgg gctggggtac ggcgatggtc gacgaaccgg
     7861 agcacgagca cggcacgaga tcggtgacga acgcactgcc cggcaccgtg accggttccg
     7921 tggtgcaagc gggcacgatc cggcaagtcg tcttcgcagc ggccacgcag caggcgctgc
     7981 cggtgccgcg ccagctgcct ccggccgtgc gtgacttcgc cggccgtggc gatcagctgg
     8041 cccggctgga cgaactcctg ctctcccacg acgagggccg gcccggcggc gtggtgatct
     8101 ccgccctcga cgggaccgcc ggggtcggca agaccgcgct ggccgtgcag tgggcccacc
     8161 gggtggagca ccacttcacc gacggcacgc tgttcgccga cctgcgtggc tacggcccca
     8221 gcgcaccggt gcggccggat ctggtgctcg cgtcgttcct ccacgtactc gggatcgcgg
     8281 aggaccgcat ccccgccgac ctggatgccc aggtcagcgt gtaccgctcg gtgctcgccg
     8341 gccgccgggt gctgatcctg ctggacaacg ccggcaccgc cgagcaggtt cgcccgctgc
     8401 tgccgggctc ccccggctgc gccgtcctgg tcaccagccg ggcgagcctg accggcctgc
     8461 tcgtcgccga agccgcgagc cagctcaccc tcgacctgtt caccgcggac gaagcccacg
     8521 tcctgctccg gcggatcctc ggccgtgagc gcgtctccgc cgagcccgca gccgtcgccg
     8581 acctcgtcga ggtgtgcgcc cgcctgccgc tggcgttgcg gatcgcggcg acgcgcatcg
     8641 ccacccgccg ccacaccagc gtcgcggaag tcgtggcgga catcgtcggc gaccggacgg
     8701 ggttggacgt gttgagcagc agcggagacg aacgcagcgc cgtgcggagc gtgttcgact
     8761 ggtcgtacac gcggctggtg gacgaacacg ccgtcctgtt ccgccggctg gggctgcatc
     8821 ccggcaccga attcggggtg cccgccgcgg cggcggtggc ggggatcgac gccgccacgg
     8881 cgtaccggca cctggaagcc ctcgccgacg tgcacctgat cgagtccgtc ggcggcaggc
     8941 gctaccggtg ccacgacttg ctgcacgcct acgccgcgca ccgcgccgaa cgggacgaca
     9001 gcccggacag ccggcgcgac gccacggccc ggcttttctc gtggtacgcg cacaccgcgc
     9061 aggccgccga caagctcgtc ttcccgggcc tggaatcccc cgctgccgac ctggcacccg
     9121 acggacccga ggtcccgctc accgaccgcg ccggggcact cgcctggctg aacaccgagc
     9181 aggcgaacct gctggcggtg ctgcgctcgg ctcccgagca ccccaccgcg gtggtactcg
     9241 ccggcgccac ccggttcctc agtctcgggc cacgcgcggt gtggccggtg cgcctcgaag
     9301 ccgaaaccct cgggctccgc gcggcggaag ccgccgggaa ccggacggcg gaggcactcc
     9361 tcctcggctt ccggggcgac accctcgcca ccttggagcg gtgggacgac gcggaagccg
     9421 acttcacccg ccagctcgcc ttggcgcggg aactcggcga cgccgtccgc cagcgagtcg
     9481 ggttgatcgg gctggggcag gtccgcttcc tgcaacggcg gtaccccgaa gcgcgtgact
     9541 actaccgcca ggcattgccg ctggcgcgac aggcgggtgg tggccgcccg gaggccgtcg
     9601 tggagtgcaa cctcagccgg atcgccgtcc ggctggggga attcggccaa gcccgcgaac
     9661 acgccgaacg ggaactcgtc ctccgccgcc ggagcgccga ccgcgtcggc gaggcctacg
     9721 ccctgcgcga cgtggccgtg gccctgcacg gactcgagga ccacgacacc gcgatcgagt
     9781 acgcgaacca agccgtcgcg ctgtaccgga ccctcgccgg caccgaggtt ttcctcgccg
     9841 aagcgctcga aacagcggcg gcctcgctcg agcgcaccgg gaacctcacg cgcgcggcgg
     9901 agcacctcgg ggaagcgtgc gagctcctcg acgagctcga cccggagcgt gccggaaccc
     9961 tgcgcgagcg gatccgggaa ctgtcctcgc gaggatgaag tcaagcgcag gtggggcagt
    10021 cgggccgcgg tgcgtcggga ccgatcgcga agctgtcctg caacgtgacg aggttgaacc
    10081 cgtactggca attggtccgc agcgcgggcg ccccggtgat gaggctcagg gtggcgtgcg
    10141 cggccagctg cccggcgacg cccgccgaaa cggcgttggc cgcgtgcgtg cgggcggctc
    10201 ggccggacgc cgcggagtag gtccgtgggg gaaggcccgc gcggcgctcg cgctcggcaa
    10261 cgcgggcgca gtcataacac ggcccggcgc cgggccggta caacccacag ccgacctggg
    10321 gcccgtggta cccgccgtgc acccacgcgg tcccggtcgc ctcgcaagcc tggttggtcc
    10381 aggagcggat ttcctcgggc tggtccgcgg ccagcagcac gacgtcgaag ccggtcgcca
    10441 gggtccgcaa cacggccggg ccgtcgaccg ccagccgcgt gccggtgacc cggacctcgg
    10501 agttctgctc gcgcaaccgg tcgaccgcga cgtcgacctt gggccggccg agatcgcgct
    10561 cggtgaagag gacttgacgg ttgaggttgg acagctcgac cacgtccggc tcgacgcagt
    10621 gcacgtgccc gactccggac ctgaccaggg cctgggcggc ggtacagccg acgccgccga
    10681 tcccgatcac cacgacccgc gccccgctca gcagcagctg cgtgtcccag ctcgtccgac
    10741 ggggagcgcg atccatccag cggaacaacg ccttgctccg cccgtaccgt tcccgctcgg
    10801 cggcggtcag ccggccgggc gccggctcgc ccgcgtcttc gacgtacccg gcgcggatca
    10861 ggtcgtcgat ggccgcccgg acgtcggtac cggcccgggt ggggtggagg cgggccaggt
    10921 cggcgacgac ctggcccgtg gtcctcgatc cgtcgagcag ctccagcagc gcccacaccc
    10981 acccgtcggg atcggcgatg tccgcggcga tcccgcggac gacaccgccg atccggacgc
    11041 gattcccgcc gtggcggacc ggaaggtgct cgggtttgat catcggacgg cgcacggctg
    11101 ctcctcgggg ttcctagctt tcctgggtcg ggttgctgaa agtcggttca cggtccgctt
    11161 cactgaattc gatcatggcg tcgcacctcc tttcccgtct gcgcccggag aaccgcgagc
    11221 ttcaccgata aacagccgtg cgaggtgggt gccggcattt gcgctccgct cggtcggtgc
    11281 ccgtctggac accggaagca tggaacccac cgaggtcaac ggcgtgtcgg gggccgtgtc
    11341 aggtgcgcga caccgagccg gcaaacgtga caaatcaatg tcagcacagg tcagggcggt
    11401 ggcgcgggcg cgcgagccga tgcgaaactc ggaatgggcg aggaagttca gcgatcccag
    11461 gaggggggaa agctggcggg atggagatcg tattcggaat tctcgggccg actgccatgc
    11521 gaatgcacgg tcgtttgcac gccgactggg gttcacccaa gctgcacaag gttctggcgg
    11581 cgttgctcac gaaccccaag gtgcgcgtgg ggatgacggg cctggcggag tgggtctggt
    11641 cggtcgacga gccggaaccg aacgatccga tttccacatt ccgcacctac gccgcgcgga
    11701 tcggcaaggt catgcgcgac gcggacgttc ccgcgacgat ccgtacggtc gacggtgcat
    11761 tgcacctcga cgtcgaacgg actgcgatcg actatttcgc cttcgaagcg ctcatcgaaa
    11821 cggctcgccg gcacagcaag gaaaacgatc acgaagcggc ttgcgaggtg gctgccaccg
    11881 ccctcggcct gtggcggggt gagccgctcg cggacctgac ctcgcagccg gcgcgggact
    11941 ggcggtattc ggcggtgcac aacgcttggc tgccggcgaa ccagctgctg ctgggcgagc
    12001 tgatcgccgt cgggcgattc gacgccgcgt tgcggaagat cgacgagctc cagcgcgaac
    12061 acccgaccga catcgggttg gccaggcgac gcctgcgcgt cctgcgcgag ctcgaccgga
    12121 cggacgacat gggcgcctac cacatcgccg tccgcaagct gctcctcgcc ggcgacgacc
    12181 aggccgcggc cgccgacttg ctcaagtact acaacacgtt gatcgccggg aagcccgctc
    12241 cgccggccag accgggagcc cggagtgccg ccgaacgact ggccgcactg ccccgccccc
    12301 ggccgccatc ggacccacca cccagcctgc tgccggcctt ggcgccacgg ggccggtcga
    12361 ccctgccgcc ggcggcgacc gatttcgtcg gtcaccacga catccggcag acgctcgacg
    12421 agctggcccg caccgccgag gggcggttct cccccggcgt gatcgtcctg gacggcttgg
    12481 cgggcatcgg aaagaccgcg ctcgcggtgc actgggcaca cgggcagtac ggccgcctcg
    12541 ccgacacggc gttgtacctc gacctgcacg gcttcgacgg cgggcgtccg gtcaccgccg
    12601 acgacgtcgt cgacgaactc ctcgacgcct tcgaagtgcc catctcccgc ctggccacgc
    12661 gcgcccgccg cgacgcgaag ctgagggaga tcctcgcgca gagccgcacc ctggtggtgc
    12721 tcgacaacgc cgcgaactcc gcgcacgtgc tgccgctgct gttcacgctc tcgccgtgcc
    12781 tgctgctcgt caccagccgc aaaggcctga ccgcgctgac cagccggcac ggcgcgcggc
    12841 ggtgctcggt cacgccgctc aacgagcagc acgccgccca ggtcctgacc aaccgcatcg
    12901 gtccgcgagg agccgccgaa caggagccgc tcgcgcggat cgccgcgttg tgcggcggag
    12961 tccccctcgc actccagctg gtcgcccacc acatcgaagg ccgtcgcgga gccgcgctga
    13021 gcgagttcgc cgacgaactc caggaccaga gccggttgct cgacatcggc gacgacggcg
    13081 acgatccgcc ggcgaccatg cgcgccgccc tgctggtcac ctacaacggc ctgccccggg
    13141 cggcgcggga cctgctgtgg ctgatcggcc tctccccggc gccggaactg actccgcacg
    13201 ccgccgccgc gctggccggg aagccggtga aagaggtcca gcacgccctc gacgtgctcg
    13261 tcagcaccca cttcctcacc cacacgggca agcgggaccg ctaccgggtc cacgacctgc
    13321 tccggacttt cgcccgcgaa ctcgcggagg ccgagcagta cgccggtgtc cgggccgagg
    13381 cggagcgccg gttgctgtcg ttctgcctgc acaccagcta cgccgccgac cgcctgctgt
    13441 tccccttccg gcccccggtc ccgatgctcc cggccgcggc ggacaccccg atggtcgaat
    13501 tcccatcgga aaacgccgcg gcggcctggc tctcgaacga gaaggccaat ttcgtgagga
    13561 tcatcccgtg ggccgcgcaa cggaatcacc acgattacgc gtggcgaatc ccccacaact
    13621 tgtacggcct ctaccgtcgg tatggttttt acaacgaact ccgcgacgcg ttcactgttt
    13681 cggtttcttc tgcccaagcc gtagcagatc cggaaagcga ggccgcgaca agaagtgact
    13741 tcggaatgat tctgctcgcc ctgggcgatc ccggtccggc attgctggaa ttccacctgg
    13801 ccgcagcgat cgcccagcag acgaacagtg cgatcggaat cgcgacgtca ttcttgcact
    13861 tgggcaccca caaagcgcag gccggcgaat tcgaggccgc cgaagccctg taccaacgcg
    13921 cactggaccg actcgaagca gccgacagcg cgggcaccga gtcggcgatc caccaccggc
    13981 tcgcagatac cctccgtcac cgcggccgtc acgatgaggc gctggcccgc taccgccacg
    14041 cgctcgacct gagggagagc atcggcaacc gccacggcca agccgaaacc ctggccgaga
    14101 tggcctcgac gttgtgcgag cagcgcaagt acggcgaagc gctcgaccac ggcctacggg
    14161 cactgcgcat cgtcgaacag atcaacgacc tcgaagtggg cccgcgcgcg tgttgcgtcg
    14221 tggccaccgt cagctaccgc caagcggacc acgcggccgc gatcggctac gcgcggcaag
    14281 ccgtgcggct ggccgcacgc acccacaacg ccgtcgtcga atccgacgcg ctccacgtcc
    14341 tcggccacgc attgcacgaa acgggacgac tggctgccgc cgaagaaggc tggacgaacg
    14401 cggcggccat ttacgccgat ctcggcaacc acgaacgtga acgacacgtt cgtgaggacc
    14461 tcgccaccct gtcgaccgcc tccgcgaacg gcactttctc ccccgaaacg tgaaacctac
    14521 tctcgttaca ttaacccgat gtggggactt gtcgatgttt acccgcgagt agtcatcgct
    14581 cgatcgaggg gaccacgact ccttcgagtc gcccgttccc gcttcgcggg gccatacgaa
    14641 ccactacggg tagaccgcgc gccagtgccg cccgatgatc agctagggtt tcggccgtgt
    14701 tcatcccccg agaacacttt ccacgaaaga gccagaggaa aagcacgatg aagaaactcc
    14761 tggccggcct cgcactggcg tccgcgctcg tcctcaccgg agcgggcgcg accggtctgc
    14821 agtactggaa tcccgagaag atcacgtcgc tcgagacggt aagcgccatc gcctgactgc
    14881 cgagccgaac cgcgacggtg gggcagtgag accccgcgct gtcccgccct cgcggccacc
    14941 tcgttcccga cccgccggga gtcggccgtg taacgtcccg gcgcgcggac cgcgacttca
    15001 ccggtgtccg gcgggcctgg tggagggaaa cgcgtgagct ggcagttcgg gccttaccgc
    15061 gtcgagtcgc tgatcgcccg gggcgggatg ggcgaggtgt accgcgcgca cgacacccgg
    15121 cacgaccggg tggtggcgct caagctgctc gcgcccgagt tcgccgccga ccgggacttc
    15181 caggagcggt tccggcggga ggcgcacgcc gtcgcgcggc tgcgggagcc gcacgtcatc
    15241 ccgattcacg cctacgggga gcacgacggg cggctctacc tcgacatgcg cctggtcgac
    15301 ggggacgacc tcggcagcag gctggccgcg ggcggggctc cctcgcccgc cgacgccgtc
    15361 gacgtcatcg ggcaggtggc gcgggcgctg gccgccgcgc acgccgaagg gctggtgcac
    15421 cgggacgtca agccgtccaa cgtgctcgtc gacgcgaccg ggttcgccta cctcgtggac
    15481 ttcggcatcg cccgcgccgc cggggccgcc accgggctca ccgcgaccgg cggggccgtc
    15541 ggcaccctcg actacatggc gcccgagcgc ttcgccgacg cgcccgccga ccaccgcgtc
    15601 gacgtctatt cgctggcttg cgtgctgcac cagtgcctga ccggcagcaa gccgttcccg
    15661 gtgacgacgg ccgcgtcgct gatcggcgcc cacctgcacc agccgccgcc ccggccgagc
    15721 gcgctgcggc ccgggctgcc cgccgcgttc gacgaggtga tcgcgcgggg catggcgaag
    15781 aacccggcgg accggttcgg ctcggtcgag gagctggccg gcgccgcgcg ggccgcgctc
    15841 ggcggcacca gcccggtccg ggcggccgct cccccgaccc ggcaggccac ccgcgtcact
    15901 cccgcacccg tttccgagcc gccccggacg tcgaaggcgc cttgggtggt ggccgcggtg
    15961 gccctgctcg ccctcgtggc cgtggcgggg tggttcacga tcctgcgccc cgcgctgcag
    16021 gaccggccga cggcgggccc ggcctcgacc tcgcccccgg ccaccaccac gccctccccc
    16081 accccgccgc cggccgccgc gccggtcacg accacgcagg tgagcgtccg gacgtccgtc
    16141 gccaccacgg tcgccgcggg cggggcggac ctcgggctgg cgaccacgat gagcacgccc
    16201 gcgtgcgacg ggtcgttcgt ggtggtcctc ggctccgccg tcaccccggc ccgctaccgc
    16261 gccgacgtcc agcgcttcct cgacctccac cccggcgcga gctacctgca cgcgccgacc
    16321 accgggtgcg ggtcgctgcg ccagcaggtg aacggcgccg acgtctacgc ggtctacgcc
    16381 gggccgttcg ccgccaagga aaccgcgtgc gcccggcgca gcggcggcgc gtacgtcaag
    16441 cggctcgacg acacgagcgc gcccacgcag gtgatcagct gctgagcccg tcccagacgg
    16501 agttggtgtc cacaaaggac ttcagcagcc cggtcagccg ggcgtcgccg cggtggttca
    16561 gctcgtcgga ggcgatgcgg cgggcgacac cggcgaggaa gtcggcgatc tggacgcggg
    16621 cgtcggcgcg ggagtcgacg aaccggacgc cggccaggcg gtggccgagg gtggccttga
    16681 gctgcagcac gcgctcgggg gtgagggcga gctgctcgtc gtgcaccagc gcgaccgggg
    16741 tgccgcccgc gctccagtgc cggacggtgt ggaccaccgc gggcaccagc ggatccagca
    16801 ccccgaccag gcccgggtcg cccgccagcc gggcgcggta ggcggccacg cgctcgccgc
    16861 cgccgcggaa gagcgcgacg atttcgccgg cttcgcccgg cgtcgcggcg aggtcgtcga
    16921 ccagcgcgaa gaaccgctcc ggcgacgtct gcacgccgcg gcgggggttg agccgcagca
    16981 cgctggtgaa cgcggtcagg aagaactccc agcgcgcggc gccgaacgcg gcgggacccg
    17041 cgcggtgcag ggtgcgggcc gccgccgcgg tgcccggccc ggccagcagc tcgaccgcgg
    17101 cccggacggc gaagtacgtc ttgtcggtca ggtgcacgtg gccgcggccc tcgagcggac
    17161 cggcggggtc gagcagccac tcgagcaccg cgcggtgctt gccgcgcagc agctggcctt
    17221 gtactcctcg gcgggcgagc cgatgcgcgc ccggatttcg cgcacgcagg ccgcggcggc
    17281 ttccgggctc agccgcaccc cggcgtgggc gaagacgtcg gtctcgccgc cgagcaggtt
    17341 ctcgccctcg gagcccgact cgtcgcaggc gatctcgacc gggctcaccc gcccgatggt
    17401 gccagagcag gcggcactcg gcgaccgctt tgcccacccg ccggcaccta ggccagggtg
    17461 accttgccgc cggtgaccgt gacggctttc ttcggcagcg gctgcgatgc cgggccgttc
    17521 gcgaccgagc cgtcggcgat cttgaacttg ctgccgtggc acgggcagtt gatcgtgccg
    17581 tccgcgacgg cgtccaccgt gcagccctgg tgggtgcaga cggcggagaa cgccgcgaag
    17641 gtgcccgccg ccggctgggt caccaccacc tgcttgtccg cgaacacctt gccgccgccg
    17701 acggggatgt cggcggcggg gccgagttcc gtgccgccgg ccgccggcgg ttgctgggcg
    17761 gccggtggcg gggcctggga gccgccgtag gtgctgcagc cggcggccag ccccgcgccc
    17821 agtaccgcca gcgccgtgcg gcgcgccagc accgggtccg tttcgtcgtc gcgcacttcg
    17881 tcctccgcct agaaggtcaa accggactgg gtgaagaacc acagcgacgc gctcagccac
    17941 agcccgacca gcccggtgaa gacgagcccg ccgagcaccg gcagcgccca cgcgggcgcg
    18001 ccgtccttgc gcagcagcag catcttcgcg acgaacgcgc cgtagaagaa gcagcccagc
    18061 agggagtgca ggaggacgcg ggtgtcgaac gactggaacc cgagcgcgta gaggcagtgc
    18121 agcgccaccg ggatggacac caggaacgcc acccggcccg accagcggtg caccgtgccc
    18181 atccacgccg gcgtagcgcc gagcttgccg tacagcgaaa gcgccgagag cagctggacc
    18241 agcaccagca cgacgacgac cgtggcgagc cacgccttca ccccctgcgg gctggagaac
    18301 ccggcgacgt tcaccgcgac gccggtcggc gtgtgcaggc tgccgtagac gcccagcacc
    18361 accgagacga cggcgccggc gaacagcggg accaggagcg tgaccgcggt gcggtgcccg
    18421 gccgtggtca tcagaagtca ccgttcccgg ccaggccgct gatcggctcg gcggtcaccg
    18481 gggcaccgtc gacgctcgcg gtgcccgcgg ccgggtcgag cggcggggcg gccgtggcgt
    18541 cgtcacccgc ggcgaggatg ccgacctggc tgccgtcggg cagcacgatc cagccggcct
    18601 tcgcctgctg ccccttcacc ttcggcgccg cgcggtagag cccggcgggc ttcttcgccg
    18661 tcggcgcggt gaactgccac gtcttgcccg acgccgtcac cgtgccggtg gccgcggtgg
    18721 cgtcgaaact gccgctcagc gcggcgttct tggcgccctt caggtccagt ttcccgccgg
    18781 tcgtcacgcc ttgcagccac gcttcgacct tcttgccgtc gcagaggtag gcgatggcgt
    18841 ggccgtcgcg caccgacacc gcgaccgacg cgccgccgcc ggtcacgcgc ccggcgtaat
    18901 ccgcccgcgc gggtgcctcg ggcttcggcg cttccgacgt cgtcgtcctg ggcggcggca
    18961 ccgccgtggt gctgcccgcc gcgctcgcgg ccccggcgac cggcgcggcg ccggtccccg
    19021 tcgccaggtt gacgatcccg atcccgccgg cgagcgcgac gcccgccagc aacgtgaaca
    19081 acggccccgg atgtttcatg atcttccccg cattcccctg acccaccacc gtgcccgtaa
    19141 cacggcggtc ggggcggaac ggctcaacgc tacgcgcgga aaagaggtat cgcttagccc
    19201 ctgcaaccgg gtggttctgg ttgactgacg ccatgctgcc ctgggaaggc gacctcgccg
    19261 gccggctcga ccggcacacg ttggagtccg agctgctgcg cggcaacccg ctcggcgacc
    19321 cgcacgaacg gccgctgtgg gtgtacgtcc cgccgggcta cgacgacggc gacgagcgct
    19381 acccggcggt ctacgtcatc cagggctaca ccgggcacgt ggcgatgtgg gccaaccgga
    19441 cgccgttccg gcagaccttc ctggagaccg ccgacgcggt cttcgccggc ggcgccccgg
    19501 gttgcgtcgt cgtgtacgtc gacgcgtgga ccgcgtacgg cggctcccag ttcgtcgatt
    19561 cgccgggcac cggccgctac cactcgtacc tgtgcgacga ggtcgtgccg tgggtggacg
    19621 cgcactaccg gacggtgccc gcggccggat cccgcgcgat cgcgggcaag tcctcgggcg
    19681 ggttcggcgc gatgatcacg ccgatgctgc gccccgacct gttcggcgcg ctcgcgacgc
    19741 acgcgggcga ctcgctgtac gagctgagct acatccagga cttcggcaag gcggcgcgcg
    19801 ccctgcgcgg ctacgaccag gacatcgcga agtggtgggc ggacttccgc tcgcgaccgg
    19861 cgttcaccaa gccggaggac gcgacgctcc tgcagctgct cggcgtctcg gcgtgcttct
    19921 cggcgcggga ggacgggacg ccggaactgc cgtgcgaccc gctgaccggc gccgtgcggc
    19981 cggaggtgtg ggagcgctgg ctggcctggg acccggtccg gatggtgccg gaccacgcgg
    20041 cggcgatccg gtcgctgcgc gcggtgtgga tcgacgcggg cacgagcgac gagtactacc
    20101 tcgacctcgg cgcggaggcc ttccgggcgg cgatcgcggc ggcggggctg ccggccgagc
    20161 gggtgcactt cgagctgttc gacgccggcc acgcggcgat cgactaccgc tacccgcttt
    20221 cgctggcgtg gctggccggg cggctcgccc ggtgaccgcc ttcgccgaac gcgacctgac
    20281 gctgcccggc gggcccgtcc tgcacgtcta cgacagcggt ggcccggggc cggccgtcct
    20341 gtggcaccac gggacgccca acctcgggtc gccgcccggg ccgctgctgc cgctcggcga
    20401 ggagctgggg atccgctgga tttcctacga ccggcccggt tacgggagct cgacgccggt
    20461 gccggggcgg tccgtcgggg acgccgccgg gtacgcgacc gccgtcgccg acgcgctcgg
    20521 ggtcgagcgc ttcgccgtcc tgggccactc cgggggcagc tcccacgcgc tcgcgtgcgc
    20581 ggcgctgctg cccgatcgcg tcctcgcggc cgccggtctc ggcgcggtgg cgccgttcca
    20641 cggtgaagcc tggttcgcgg gcatggcgga cccgggttcg ctgcgcgccg ccaccgaagg
    20701 ccgggctgcc aaggagaagt acgaagcggc tgcccagttc aaccccgcgg tgttcaccga
    20761 ggccgacttc gccgcgctta agggggcgtg gtcctggctc gacagcgtcg tccagcccgc
    20821 gctgggggcg gtcgggctga tcgacgacga cctcgcctac gtcgcgccgt ggggcgccga
    20881 cccggccgcc atcaccgcgc cggtgctgct ggtgcacggc gaggacgacc ggatggtgcc
    20941 cgccgcgcac agccggtggc tcgccggacg ctgccccggc gccgaactcc ggctcacccc
    21001 cggcgacggg cacctctccg tgctggacca cgccgccgcc gcgctcacct ggctcgccgc
    21061 tcaagcgagc agcgccagcg aggccacgac cggcg
//
