LOCUS       NZ_CP095376            20249 bp    DNA     circular CON 06-NOV-2024
DEFINITION  Amycolatopsis sp. FBCC-B4732 chromosome, complete genome.
ACCESSION   NZ_CP095376
VERSION     NZ_CP095376.1
KEYWORDS    RefSeq.
SOURCE      Amycolatopsis sp. FBCC-B4732
  ORGANISM  Amycolatopsis sp. FBCC-B4732
            Bacteria; Bacillati; Actinomycetota; Actinomycetes;
            Pseudonocardiales; Pseudonocardiaceae; Amycolatopsis.
REFERENCE   1  (bases 1 to 10190959)
  AUTHORS   Choi,A.
  TITLE     Complete Genome Sequence of Amycolatopsis pretoriensis strain
            FBCC-B4732
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 10190959)
  AUTHORS   Choi,A.
  TITLE     Direct Submission
  JOURNAL   Submitted (07-APR-2022) Bioresources Collection & Research Team,
            Nakdonggang National Institute of Biological Resources, Donam 2-gil,
            Sangju-si, Gyeongsangbuk-do 37242, South Korea
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: HGAP v. 3.0
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 75.1x
            Sequencing Technology             :: PacBio RSII
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_023008405.1-RS_2024_11_06
            Annotation Date                   :: 11/06/2024 10:39:22
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.8
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 9,364
            CDSs (total)                      :: 9,298
            Genes (coding)                    :: 9,177
            CDSs (with protein)               :: 9,177
            Genes (RNA)                       :: 66
            rRNAs                             :: 4, 4, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 4, 4, 4 (5S, 16S, 23S)
            tRNAs                             :: 51
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 121
            CDSs (without protein)            :: 121
            Pseudo Genes (ambiguous residues) :: 0 of 121
            Pseudo Genes (frameshifted)       :: 50 of 121
            Pseudo Genes (incomplete)         :: 81 of 121
            Pseudo Genes (internal stop)      :: 14 of 121
            Pseudo Genes (multiple problems)  :: 19 of 121
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 05:14:56
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 3344077
            Orig. end                         :: 3364326
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP095376.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            Bacteria and source DNA available from NNIBR.
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..20249
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="RRE-containing"
                     /region_number="20"
                     /rules="minimum(1, [Bottromycin_Methyltransferase_RRE,
                     Cyanobactin_D_RRE, Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /tool="antismash"
     cand_cluster    1..20249
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /kind="single"
                     /product="RRE-containing"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..20249
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:10249](+)"
                     /cutoff="10000"
                     /detection_rule="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /neighbourhood="10000"
                     /product="RRE-containing"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..10249
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /neighbourhood="10000"
                     /product="RRE-containing"
                     /protocluster_number="1"
     gene            251..2323
                     /locus_tag="MUY14_RS14395"
                     /old_locus_tag="MUY14_14395"
     CDS             251..2323
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003094033.1"
                     /locus_tag="MUY14_RS14395"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MUY14_14395"
                     /product="putative Ig domain-containing protein"
                     /protein_id="WP_247025133.1"
                     /transl_table=11
                     /translation="MLSAALGAAVGLLGTVAVAAPAEAAAVCGDQVVGNGGFESGTTPW
                     TQTSGVISAATTAEPSHGGTMDAWLDGYGSTHTDTLSQSLTLPAGCASAALSWWAHVDT
                     KETTTTTAYDKLVVQVGTDTLASYSNLDKNTGYVQRTVDVSRYLGQTVTLKVTGTEDSS
                     LATNFLLDDFSLTTTGSQNPQSPVVTSPGAQTGAVGQAASLQVQASDPQGDALTWTATG
                     LPAGLTIGASTGKITGTPTAAGTSSVTVTAKDPAGNSGSATFAWTITAAPADSTRTPIN
                     PAYTVNLTSNTAGDTWNGHQSVSFTNGSATALPEVYLRLWDNYHGTCPTTPITVTNVTG
                     GTPSALSVDCTAMKITLPAPLAQGQSATIGFDLKIVVPSGADRFGHDGAYNMIGNALPV
                     LAVRDGAGWHLDPYTNNGESFYTVISDFDVTLVHPTALLTPATGTSTETTSGSTTTTRA
                     VANKVRDFAWGAGPFAKISTTSGKGVRVNVYSVSGISTSSANQMLSLAADSIDVHSGRF
                     GDYPYGEVDVVLDNNFWFGGMEYPGFVLDLVSTTALPHELAHQWFYGIVGDDEYNSPWL
                     DESFTDYATDLYRGVTGSGCGITWQSSAEKLTNSMAYWDAHSSRYSTVVYNYGKCTLHD
                     LRRLIGDTAMANLLKSYAQSHWYGVSTTAEFKAAAQAAAGSTDLTSFWASHRVEG"
     gene            2370..3227
                     /locus_tag="MUY14_RS14400"
                     /old_locus_tag="MUY14_14400"
     CDS             2370..3227
                     /EC_number="2.3.1.-"
                     /GO_function="GO:0016747 - acyltransferase activity,
                     transferring groups other than amino-acyl groups [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013226373.1"
                     /locus_tag="MUY14_RS14400"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MUY14_14400"
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="WP_247023503.1"
                     /transl_table=11
                     /translation="MDGERLFCDVALAARIERAEVRLVVESSDAARARRGDDVGFARPF
                     AGGVASFAEADSPYNKVAGVGFDGPPDGLEEIEAAYAELGAPVQIEVSQLADASFGGHL
                     TDRGYRLENYENVLGRRVADAGFPDFVRRSGDDELETWLAAIADASVVADTEGLASHEE
                     FSRETIVDALRDMPGMLRFTAEREGEFAGGAGLRVADGIAQLGAAATLPAHRRRGVQTA
                     LVRARLATAAALGCDLAVVTTQPGSKSQQNVQRLGFELLYARAILVKGASAASSSGAES
                     RQAS"
     gene            complement(3152..3508)
                     /locus_tag="MUY14_RS14405"
                     /old_locus_tag="MUY14_14405"
     CDS             complement(3152..3508)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014467130.1"
                     /locus_tag="MUY14_RS14405"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MUY14_14405"
                     /product="MmcQ/YjbR family DNA-binding protein"
                     /protein_id="WP_247023504.1"
                     /transl_table=11
                     /translation="MTVTVQKLERLLDGLAEVQRSEARDYSSFSVRGKRFGYFWPRTRT
                     VGLKQEISEQLALVAERPDVFEVQFTAGGFGWVVVYLDGIGADELAELLYEAWRLSAPE
                     ELAAEAPFTRIARA"
     misc_feature    complement(3471..3486)
                     /note="TFBS match to LexA_variant_1, Repressor of DNA
                     damage response, confidence: weak, score: 23.58"
                     /tool="antismash"
     gene            3564..4331
                     /locus_tag="MUY14_RS14410"
                     /old_locus_tag="MUY14_14410"
     CDS             3564..4331
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) APH"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020635709.1"
                     /locus_tag="MUY14_RS14410"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MUY14_14410"
                     /product="fructosamine kinase family protein"
                     /protein_id="WP_247023505.1"
                     /sec_met_domain="APH (E-value: 9.9e-15, bitscore: 54.2,
                     seeds: 156, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSIREAVLDDGRVVVVKRGHAPGAAAAEAAGLRWLAAADAVAVPV
                     VHSHDDEQLVLDRVPAGRPSAAAAERFGRGLARLHAAGAPAFGAAPPGGPADAWIGLAP
                     MANVPGEDWASWYAAHRVLPYVRRAVDAGTFGPAEAAVFERACARFPALDEPPSRLHGD
                     LWNGNVLWDGEDGWLIDPAAHGGHRETDLAMLQLFGCPHLDRVLAAYQEEAPLAGGWAE
                     RIELHQLFPLLVHTVLFGRSYAGQALAAARSLR"
     gene            complement(4328..4984)
                     /locus_tag="MUY14_RS14415"
                     /old_locus_tag="MUY14_14415"
     CDS             complement(4328..4984)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013226371.1"
                     /locus_tag="MUY14_RS14415"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MUY14_14415"
                     /product="HNH endonuclease family protein"
                     /protein_id="WP_247023506.1"
                     /transl_table=11
                     /translation="MPRTQALVLLAVLTGAAVTGCKVPDDLASGAQPTGTAAAAPVAPA
                     EARAELGQLKVAVRGTMDGYSREKFPHWDKVEGACDTREQVLKRDGKDVTTNSDCAAKS
                     GTWVSAYDGQTWHKASDVDIDHMVPLGQAWVSGAKSWTQERREQFANDLVRPQLHAVTD
                     NLNEQKSDKAPDQWKPPLVSYWCTYATDWIVVKRNYGLTITVPEKTALESMLQHC"
     gene            complement(5067..5792)
                     /locus_tag="MUY14_RS14420"
                     /old_locus_tag="MUY14_14420"
     CDS             complement(5067..5792)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003101575.1"
                     /locus_tag="MUY14_RS14420"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MUY14_14420"
                     /product="hypothetical protein"
                     /protein_id="WP_247023507.1"
                     /transl_table=11
                     /translation="MELLRSWGRGPDHLTGLALAGIALPGPEFVDALVFTRTGVVVIAA
                     HEPGPDPGSGERAGAAVAAAQGALAGHEGGRYVTGLVAVVPGLPAPGAHWDEPATVPGV
                     AVVLADPRSLRRIIVQHNRWRTVWSADDVLDACYALSLAHLAPPRSALVADGFPVRLPD
                     RSRLPELPAVVPIPAEPPPAAEEPGEPAVPLPRRPGSAVFPRPRPIRQVPWGLLAVLTL
                     LVTAGVIAAVFVAQVFHGS"
     gene            5995..6864
                     /locus_tag="MUY14_RS14425"
                     /old_locus_tag="MUY14_14425"
     CDS             5995..6864
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020647474.1"
                     /locus_tag="MUY14_RS14425"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MUY14_14425"
                     /product="urea carboxylase-associated family protein"
                     /protein_id="WP_247023508.1"
                     /transl_table=11
                     /translation="MGAPPPAYQGAALEVDRSFYRRLAAEPGRVRVDAFEIPIRSGRAW
                     RVPKGHLCRLSTVEGPQVGDLNLWHADDPRERFWAARTRQLQRAHVSTFDRLWSTLPFL
                     RPLATITADTLEHHGVDGDGGRVHDLLGTRCDPYVNRLLTGEDFDFHCHSNLVRAVAPF
                     GLTEFDVHDVLNVFQCTGLTEDDRYFMKACPARPGDHFEFFAEADLLCALSTCPGGDLS
                     VPLWGPDARDPIDVCHPIGVEVFAPRADLLEGWSPPARAAYRGLHGVRLPEWADLPDRT
                     GRRGEPAG"
     gene            7179..8786
                     /locus_tag="MUY14_RS14430"
                     /old_locus_tag="MUY14_14430"
     CDS             7179..8786
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0043565 - sequence-specific DNA binding
                     [Evidence IEA]"
                     /GO_process="GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1112: sigma-54
                     dependent trancsriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017981323.1"
                     /locus_tag="MUY14_RS14430"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MUY14_14430"
                     /product="sigma-54-dependent Fis family transcriptional
                     regulator"
                     /protein_id="WP_247023509.1"
                     /transl_table=11
                     /translation="MDLRTEIAQSWRRAELSGLSPASAIDRLDVADVDSRSRLLRAASP
                     VLDELARQLAGTRFCVVLADDECRIVARRFTERSVELALENVSAVPGCQFIEERTGTNS
                     LATPFETRRGVSVDGDEHFLEAMKQFTCYGHPLVHPSTRRLAGVLDITGPAGDANPLLG
                     PFLRRAVADIERRLLDGAKLAEQQLLAAFQSVQHRACAVLALGQDVVLANTAATELVDT
                     ADHRLLQDLGRTQRGLRRIRLTSGTPVEVRVEAVSANAGLLFELAPVRPASPVVSRPRA
                     ARGLFPAPIEDRLHRAGHARRRVLVCGEPGAGRSTAARVIAGDEPVREFDASDVVAGEA
                     DWCARVEAAASSRGLLVIDGIQLLPPLAAVRLARLLDESPAWFALLSGPPSELHGEQAT
                     LAARVHRRIELPPLRERRDEIPAIARELLRGFGASLRLTPGALELLASQHWPGNLRELE
                     GVLAAAADRRSAGDLTAADLAPDCTETGGALTGWEQAEYDVIVRTLRACDGNKVRAAKQ
                     LGISRSTLYNRMRALRVR"
     gene            8878..9987
                     /locus_tag="MUY14_RS14435"
                     /old_locus_tag="MUY14_14435"
     CDS             8878..9987
                     /EC_number="1.1.99.36"
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /GO_function="GO:0051287 - NAD binding [Evidence IEA]"
                     /NRPS_PKS="Domain: PKS_ER (22-285). E-value: 2.2e-10.
                     Score: 32.1. Matches aSDomain:
                     nrpspksdomains_MUY14_RS14435_PKS_ER.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ADH_N"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ADH_zinc_N"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1040: alcohol dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009157103.1"
                     /locus_tag="MUY14_RS14435"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MUY14_14435"
                     /product="NDMA-dependent alcohol dehydrogenase"
                     /protein_id="WP_247023510.1"
                     /sec_met_domain="ADH_N (E-value: 6.5e-29, bitscore: 99.1,
                     seeds: 66, tool: rule-based-clusters)"
                     /sec_met_domain="ADH_zinc_N (E-value: 8.4e-22, bitscore:
                     76.6, seeds: 86, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKTKAAVLFDAGKPFEIMELDLDGPGPGEVLIKYTAAGLCHSDLH
                     LIDNDLVPRFPIIGGHEGAGVIEEVGPGVTKVAPGDHVVCSFIPNCGTCRYCSTGRQNL
                     CDMGATILDGHLPDGTFRFHGGGQDFGAMCMLGTFSERATISQHSVVKVDDWLPLETAV
                     LVGCGVPTGWATANYAGGVRAGDTTVVYGIGGIGINAVQGAAHAGAKYVVAVDPVEFKR
                     EAALKFGATHAFATAAEAAEKVNELTWGQLADQALITVGTVEEDVVSEAFNVVGKGGTV
                     VITGLANPEKLTVHVSGGVMTLFEKTIKGTLFGSANPQYDIVRLLRLYDAGKLKLDELV
                     TRKYTLEQVNEGYQDLRDGKNIRGVIVHA"
     aSDomain        8944..9732
                     /aSDomain="PKS_ER"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_MUY14_RS14435_PKS_ER.1"
                     /evalue="2.20E-10"
                     /label="MUY14_RS14435_PKS_ER.1"
                     /locus_tag="MUY14_RS14435"
                     /protein_end="285"
                     /protein_start="22"
                     /score="32.1"
                     /tool="antismash"
                     /translation="DGPGPGEVLIKYTAAGLCHSDLHLIDNDLVPRFPIIGGHEGAGVI
                     EEVGPGVTKVAPGDHVVCSFIPNCGTCRYCSTGRQNLCDMGATILDGHLPDGTFRFHGG
                     GQDFGAMCMLGTFSERATISQHSVVKVDDWLPLETAVLVGCGVPTGWATANYAGGVRAG
                     DTTVVYGIGGIGINAVQGAAHAGAKYVVAVDPVEFKREAALKFGATHAFATAAEAAEKV
                     NELTWGQLADQALITVGTVEEDVVSEAFNVVGKGGTVVITG"
     gene            10001..10249
                     /gene="mftB"
                     /locus_tag="MUY14_RS14440"
                     /old_locus_tag="MUY14_14440"
     CDS             10001..10249
                     /GO_process="GO:0140604 - mycofactocin biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="mftB"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RRE-containing: Mycofactocin_RRE"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:TIGR03967.2"
                     /locus_tag="MUY14_RS14440"
                     /note="MftB, a small protein, is a peptide chaperone that
                     assists the radical SAM enzyme MftC in performing two
                     modifications to the C-terminal Val-Tyr dipeptide of the
                     mycofactocin precursor peptide, MftA. MftB's role is
                     analogous to the role of PqqD in the biosynthesis of PQQ, a
                     cofactor that derives entirely from a Tyr and a Glu in the
                     precursor PqqA; Derived by automated computational analysis
                     using gene prediction method: Protein Homology."
                     /old_locus_tag="MUY14_14440"
                     /product="mycofactocin biosynthesis chaperone MftB"
                     /protein_id="WP_247023511.1"
                     /sec_met_domain="Mycofactocin_RRE (E-value: 2.9e-07,
                     bitscore: 29.7, seeds: 14, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDLDAPYRVNPHEPFEVLVHRCEHRDGCLLGTPDVVRFVRALAMH
                     ATARDAIDAAELGETTRARVVAALEHLAATGVIVAEP"
     aSDomain        10034..10234
                     /aSDomain="Mycofactocin_RRE"
                     /aSTool="RREfinder"
                     /database="RREFam.hmm"
                     /description="Stand-alone RRE protein in a mycofactocin
                     cluster"
                     /detection="hmmscan"
                     /domain_id="rrefinder_MUY14_RS14440_Mycofactocin_RRE.1"
                     /evalue="8.70E-10"
                     /identifier="RREFam016.1"
                     /label="MUY14_RS14440"
                     /locus_tag="MUY14_RS14440"
                     /protein_end="78"
                     /protein_start="11"
                     /score="29.7"
                     /tool="antismash"
                     /translation="HEPFEVLVHRCEHRDGCLLGTPDVVRFVRALAMHATARDAIDAAE
                     LGETTRARVVAALEHLAATGVI"
     gene            complement(<10363..10777)
                     /locus_tag="MUY14_RS14445"
                     /old_locus_tag="MUY14_14445"
                     /pseudo=""
     CDS             complement(<10363..10777)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011726646.1"
                     /locus_tag="MUY14_RS14445"
                     /note="frameshifted; incomplete; partial in the middle of a
                     contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /old_locus_tag="MUY14_14445"
                     /product="IS1634 family transposase"
                     /pseudo=""
                     /transl_table=11
                     /translation="MCGADRVLRGSRDIEHIGSAHDDAALEALTAVARQRRCRPVVGRL
                     RSRRRGWSTCGTRSATPTSCGGWRRLLVVTRCSDYWCWQGSSSRPASWTVCGWSRRQVG
                     VRDPQAASARVRERALAAEVGRGMRPHR"
     misc_feature    complement(10755..10769)
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: weak, score: 17.38"
                     /tool="antismash"
     misc_feature    10861..10876
                     /note="TFBS match to RutR, Regulator of the pyrimidine and
                     purine metabolism, confidence: weak, score: 20.2"
                     /tool="antismash"
     gene            10869..11216
                     /locus_tag="MUY14_RS14450"
                     /old_locus_tag="MUY14_14450"
     CDS             10869..11216
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003057792.1"
                     /locus_tag="MUY14_RS14450"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MUY14_14450"
                     /product="VOC family protein"
                     /protein_id="WP_247023512.1"
                     /transl_table=11
                     /translation="MVMRVAIPVLPCRDVQAARSYFTDVLGFDTIFTWETPPSYAAVIR
                     DTAEFHLYAESSVGPARVTVVVDDVDSCHDELRARGADIVEPLADRPYGMRDFNVRTPD
                     GHLLIFSQPLT"
     gene            complement(11229..11378)
                     /locus_tag="MUY14_RS14455"
                     /old_locus_tag="MUY14_14455"
     CDS             complement(11229..11378)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="MUY14_RS14455"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="MUY14_14455"
                     /product="hypothetical protein"
                     /protein_id="WP_247023513.1"
                     /transl_table=11
                     /translation="MQRPSRRWAERRFPNIRYWNEPGKGGHFAAFEQPALFVDEVRSFF
                     RLVR"
     misc_feature    11376..11385
                     /note="TFBS match to ToxT, Regulator of MSHA biosynthesis,
                     confidence: weak, score: 13.55"
                     /tool="antismash"
     gene            complement(11655..13388)
                     /locus_tag="MUY14_RS14460"
                     /old_locus_tag="MUY14_14460"
     CDS             complement(11655..13388)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) TPP_enzyme_N"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) TPP_enzyme_C"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1055: pyruvate oxidase/decarboxylase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013226369.1"
                     /locus_tag="MUY14_RS14460"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MUY14_14460"
                     /product="pyruvate dehydrogenase"
                     /protein_id="WP_247023514.1"
                     /sec_met_domain="TPP_enzyme_N (E-value: 1.6e-42, bitscore:
                     144.1, seeds: 75, tool: rule-based-clusters)"
                     /sec_met_domain="TPP_enzyme_C (E-value: 8.9e-36, bitscore:
                     122.1, seeds: 323, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MATVAEQLVRTLRDAGVERIYGIVGDSLNPIVDAVRRIDGIEWVH
                     VRHEETAAFAAAAEAQVTGKLAVCAGSCGPGNLHLINGLFDAHRSGAPVLAIASHIPSN
                     QIGTGFFQETHPDRLFTECSHFSEVVADPAQLPRLLRIATQAAVGKGGVAVLTIPGDLA
                     DRKATGPLTERLPLVEPSPPVPSADAVQKLADLLNSGEKVMLFAGAGVRGAHEEVMALA
                     EKLAAPVGHSLGGKEWIQYDNPFDVGMSGLLGYGACYDAMHEADRIVLLGTDFPYDKFL
                     PQARTIQVDHDASRLGRRTPLDLAVHGDVKETLRALLPLLRPRTERAYLDRMLREHVRK
                     LEKVVGAYTGKIEQRRPIHPEYVASVLDEVAADDAVFTVDTGMGNVWAARYLTPNGRRR
                     VLGSFRHGSMANALPHAIGAQLSQPGRQVVSLSGDGGLAMLMGDLLTLPAYEVPVKVVV
                     FNNATLGMVKLEMLVDGLPDFGTDHAPVNFAAIAAACGVFAERVEDPADVRGALEKAFA
                     HPGPAVVEVVTDPNALSIPPRITGEMVRGFALGATKTVLNGGVGKMVDLARANLRNAPR
                     P"
     misc_feature    13420..13435
                     /note="TFBS match to LexA_variant_1, Repressor of DNA
                     damage response, confidence: weak, score: 20.68"
                     /tool="antismash"
     misc_feature    complement(13435..13453)
                     /note="TFBS match to LexA_variant_3, Repressor of DNA
                     damage response, confidence: weak, score: 19.87"
                     /tool="antismash"
     misc_feature    complement(13456..13469)
                     /note="TFBS match to ArgR, Regulator of arginine
                     biosynthesis genes, confidence: weak, score: 16.21"
                     /tool="antismash"
     gene            13459..14361
                     /locus_tag="MUY14_RS14465"
                     /old_locus_tag="MUY14_14465"
     CDS             13459..14361
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1014: LysR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013226368.1"
                     /locus_tag="MUY14_RS14465"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MUY14_14465"
                     /product="LysR family transcriptional regulator"
                     /protein_id="WP_247023515.1"
                     /transl_table=11
                     /translation="MDVQMLRLFREVAGGATVTETAAGAHLTQPALSRALRRLEHEAGA
                     ELFRRSGRLLRLTPAGHVFKRHAGLVLDQLDQGLREVADIVAPGAGVVPLAFLHTFGTW
                     LVPDVLSGFLREHASTRFELRQHGEAGLEAELLEGTADLVLTSGDPGHPQLHWERLLVE
                     PLRLAVPPHHRLAGRHRVRLADVADETFILLRPGYALRETTERLCAEAGFAPRIGFEGD
                     EVETLRGLVTAGLGVSVLPLPHTAAFPAPHLELTDVDAARDIGLAWVAGRNLPAPSETF
                     RRHVLDTVPGRFDRPQGTM"
     gene            14413..15507
                     /locus_tag="MUY14_RS14470"
                     /old_locus_tag="MUY14_14470"
     CDS             14413..15507
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020647473.1"
                     /locus_tag="MUY14_RS14470"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MUY14_14470"
                     /product="calcium:proton antiporter"
                     /protein_id="WP_247023516.1"
                     /transl_table=11
                     /translation="MAALRSFLTSWTSVTPVLGILVLALAWGRDLGPVFVAIVAIALGA
                     TVLAAVHHAEVVAHRVGEPFGSLVLAVAVTVIEVALIVTMMVSGGPDAGSLARDTVFAA
                     VMITTNGIVGISLLVGARRYGVTLFNSEGSGAALATVATLATLSLVLPTFTSSTPGPAF
                     SSAQLTFAAVASLALYATFVLTQTMRHRDFFLPVAADGEVKEDDHAEPPTNRAALGSLA
                     LLLIALVAVVGLAKVESPAIEAGVRAAGFPQSFVGVVIALLVLLPETLAATRAAQRDRM
                     QISLNLAYGSAIASIGLTIPAIALASLWLPGELLLGLGSTQIVLLALTVVVSVLTVVPG
                     RATRLQGGVHLVLLAGFLVLAVNP"
     gene            complement(15556..17928)
                     /locus_tag="MUY14_RS14475"
                     /old_locus_tag="MUY14_14475"
     CDS             complement(15556..17928)
                     /GO_function="GO:0016791 - phosphatase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1054: hypothetical
                     protein"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003101554.1"
                     /locus_tag="MUY14_RS14475"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MUY14_14475"
                     /product="SpoIIE family protein phosphatase"
                     /protein_id="WP_247023517.1"
                     /transl_table=11
                     /translation="MTADEELLPVPGRPAEVSANLARLAETVARLRGEVDHAHAVADGR
                     ALIELAKGVLMERLHCTPADAARQLESLAGRAGLTPLEFAADVVGEAAEDRITEVAQEF
                     LARAEGEDSVAVRLRTAESGVLAAGDTQRVAESILEHALRPLGATAVAVWLAGPDGSLT
                     LAGSAGFSAEEAARWRYVPPGVATPARNALLERDTVWYPTLSGAGLPSLGQHTLSGGGR
                     VAVPTGTGGRIIGVVEMCWPEPLPAEPGRQRRQLEALAELCGHTLDTWDGVVAPVAAGS
                     GDFLSELVDFVDGLHDPAVLLSPCVDGGRLTDFRIHHANVRFADPGGRPRSRIVGTRLL
                     EAYPLAAEESGLLDKIRRVYATGEPFRAGSLPVTTLVDQVPLTVHTDVSVTRFAGNVLL
                     ILRIQDDAAKLAVLLQHAQRLGRIGGFEENVVTGTITWNTELFALYGLPPTATPLSLHE
                     LATHAHPDDGPAIGRFLRAVLHHQRPSSTAFRLQRSDGVARHIRVVAEPVADAAGELLA
                     VRGAYQDVSSQHWTEVALAATRDKLAETEQQSIERNRLALQLQHAIMPPAKGPIDMPGL
                     RAAVRYRPAEKEHLVGGDWYDAVALPTGEVLLCVGDVAGHGIDAATGMVSLRNALRGLA
                     ATGAGPAQLLTWLNLVAYHLTDHVTATAVAAVYDPATRALRWARAGHLPPIVRHRDGEV
                     TTLPLIRGSLLGAVRDVTYQEEEIRLAEGDILLIYTDGLIERRDRPVQETVSRLVTLVE
                     RHEGGLEHQLDTLLTYSTADTDDDTCVVGIEVRSASS"
ORIGIN
        1 cccgcgccaa ctactccgcc taccgggccc ggaccgccaa gggcttcggg gagatgatcc
       61 ggtcggcggt ctccgccgtc gtcgcggtgg ccggcgcgct cgtgctgctc ttcatcctgc
      121 tgaacgtgct ccagcaggcc tgaacccgga acccgactca tggcgggttg ttgccgcccc
      181 caccgcgggg gacccttttc cgtggccccg acggacgggg ccgcgaaagg actcccccat
      241 gagatcgagg gtgctttctg ctgcgctcgg tgcggccgta ggcctgctgg gcacagtcgc
      301 cgtcgccgcg ccggccgagg ccgcggcggt ttgcggtgac caggtcgtcg gcaacggcgg
      361 gttcgaaagc ggcaccacgc cgtggaccca gaccagcggg gtcatctccg ccgccaccac
      421 ggcggaaccg tcgcacggcg gcacgatgga cgcctggctc gacggctacg gcagtacgca
      481 caccgacacc ctgtcccagt cgctgacgct gcccgcgggc tgcgcgtcgg cggccctttc
      541 gtggtgggcg cacgtcgaca ccaaggagac gacgaccacc accgcctacg acaagctcgt
      601 cgtccaggtc ggcaccgaca ccctcgcgag ctactcgaac ctcgacaaga acaccgggta
      661 cgtccagcgc accgtcgacg tgtcgcgcta cctgggccag acggtgacgc tcaaggtcac
      721 cggcaccgag gactcgagcc tcgccaccaa cttcctcctc gacgacttct cgctgaccac
      781 caccggttcg cagaacccgc agtccccggt cgtcacctcg cccggcgccc agaccggcgc
      841 cgtcggccag gccgcgtccc tgcaggtcca ggccagtgac ccgcagggcg acgcgctcac
      901 ctggaccgcg accggcctgc ccgccggcct gacgatcggc gcgagcaccg ggaagatcac
      961 cggcacgccg acggcggccg ggacgtcgtc ggtgacggtc accgccaagg accccgccgg
     1021 caacagcggc agcgccactt tcgcgtggac gatcaccgcg gcacccgccg actcgacgcg
     1081 caccccgatc aaccccgcct acacggtgaa cctcacgtcg aacaccgcgg gcgacacctg
     1141 gaacggccac cagagcgtca gcttcaccaa cggctccgcg accgcgctgc ccgaggtcta
     1201 cctgcggctc tgggacaact accacggcac ctgcccgacc acgccgatca cggtcacgaa
     1261 cgtcaccggc ggtacgccgt ccgcgctgag cgtggactgc acggccatga agatcacgct
     1321 gccggcaccg ctcgcgcagg gccagtcggc gaccatcggg ttcgacctga agatcgtcgt
     1381 gcccagcggc gccgaccggt tcggccacga cggcgcgtac aacatgatcg gcaacgcgct
     1441 accggtgctc gcggtccgcg acggcgcggg ctggcacctc gacccctaca ccaacaacgg
     1501 cgagtcgttc tacaccgtga tcagcgactt cgacgtcacg ctggtgcacc cgacggcgct
     1561 gctgaccccg gccaccggga cgtcgaccga gacgaccagc ggcagcacga ccaccacccg
     1621 cgccgtcgcg aacaaggtgc gcgacttcgc ctggggcgcc gggccgttcg ccaagatcag
     1681 cacgacgtcc ggcaagggcg tgcgggtgaa cgtctactcg gtcagcggga tctccaccag
     1741 cagcgccaac cagatgctga gcctggccgc cgactccatc gacgtccact cgggccgctt
     1801 cggcgactac ccgtacggcg aggtggacgt ggtgctggac aacaacttct ggttcggcgg
     1861 catggagtac ccgggcttcg tgctggacct cgtgtcgacc acggcgctcc cgcacgagct
     1921 ggcgcaccag tggttctacg ggatcgtcgg cgacgacgag tacaactccc cgtggctgga
     1981 cgagagcttc accgactacg ccaccgacct ctaccgcggg gtcaccggaa gcggctgcgg
     2041 catcacgtgg cagtcgagcg cggagaagct gaccaactcg atggcctact gggacgcgca
     2101 ttcgtcgcgg tactccacgg tcgtctacaa ctacggcaag tgcacgctgc acgacctgcg
     2161 gcggctgatc ggcgacacgg cgatggcgaa cctgctgaag tcctacgccc agtcgcactg
     2221 gtacggcgtg tcgaccaccg cggagttcaa ggcggcggcg caggcggcgg ccgggtcgac
     2281 cgacctgacg tcgttctggg cgtcgcaccg cgtggagggc tgagcgaaat tcggttccgt
     2341 tccccgtcca cgtccgccac cctggggaca tggacgggga acggcttttc tgcgacgtcg
     2401 cgctggcggc ccggatcgaa cgcgccgagg tgcggctggt cgtcgagagc agcgatgcgg
     2461 cacgagcccg ccggggcgac gacgtcggct tcgcgcggcc gttcgccggc ggggtcgcga
     2521 gcttcgcgga ggcggactct ccgtacaaca aggtcgccgg ggtcggcttc gacggcccgc
     2581 ccgacgggct ggaggagatc gaagcggcct acgccgagct gggcgcacca gtgcagatcg
     2641 aagtgtcaca gctggcggac gcgtccttcg gcgggcacct gaccgaccgg ggctaccggc
     2701 tggagaacta cgagaacgtg ctcggccgcc gggtcgccga cgccggcttc cccgacttcg
     2761 tccggcgctc cggggacgac gagctggaga cgtggctggc cgccatcgcc gacgcgtccg
     2821 tcgtggccga caccgaaggc ctggcctcgc acgaggagtt ctcgcgcgag accatcgtcg
     2881 acgcgctgcg cgacatgccg gggatgctgc ggttcacggc ggaacgcgag ggcgaattcg
     2941 ccggcggcgc cgggcttcgc gtcgccgacg ggatcgcgca gctgggcgcc gcggcgacgc
     3001 tgcccgccca ccgccgccgc ggcgtgcaga cggccctggt gcgcgcccgg ctcgcgaccg
     3061 ccgccgcctt ggggtgcgac ctcgccgtcg tcaccacgca gccggggtcg aagtcgcagc
     3121 agaacgtgca gcggctgggg ttcgaactgc tctacgcgcg ggcgatcctg gtgaagggcg
     3181 cctcggcggc gagctcctcg ggcgccgaaa gccgccaggc ctcgtagagc agttcggcca
     3241 gctcgtcggc gccgatcccg tcgaggtaca cgaccaccca gccgaacccg cccgcggtga
     3301 actggacctc gaagacgtcg gggcgctccg ccacgagcgc cagctgctcg gagatctcct
     3361 gcttgaggcc gacggtccgg gtccgcggcc agaagtagcc gaaccgcttg ccgcgcacgc
     3421 tgaacgacga gtagtcgcgc gcttcggagc gctggacctc cgccagcccg tcgagcagcc
     3481 gttcgagctt ctggaccgtg accgtcacct gtcgttcccc ctgtctccgg cgcctacgtt
     3541 agcgcgccgg tacggtgcgg gacatgagca tccgcgaagc cgttctcgac gacggccgcg
     3601 tggtggtggt caagcgcggg cacgcccccg gcgcggccgc cgccgaggcc gccgggttgc
     3661 gctggctggc cgcggcggac gcggtcgcgg tgccggtggt gcacagccac gacgacgaac
     3721 agctggtgct cgaccgcgtc ccggccggac gcccgagcgc ggcggcggcc gagcggttcg
     3781 ggcgcgggct cgcgcggctc cacgcggccg gggcgccggc gttcggcgcc gctcccccgg
     3841 gcggacccgc cgacgcctgg atcggcctgg ccccgatggc gaacgtcccc ggggaggact
     3901 gggcgtcgtg gtacgccgcg caccgggtgc tgccctacgt ccggcgcgcg gtcgacgccg
     3961 ggacgttcgg cccggccgag gccgcggtct tcgagcgcgc ctgcgcccgg ttccccgcgc
     4021 tcgacgaacc gccgtcccgg ctgcacggcg acctgtggaa cggcaacgtc ctgtgggacg
     4081 gcgaagacgg gtggctgatc gacccggccg cgcacggcgg gcaccgcgag acggacctgg
     4141 cgatgctgca gctgttcggc tgcccgcacc tcgaccgcgt cctcgccgcc taccaggagg
     4201 aagccccgct ggccggcggc tgggcggagc ggatcgagct gcaccagctg ttcccgctgc
     4261 tggtgcacac cgtcctgttc ggacggtcct acgccgggca ggcgctggcg gcggcgcgct
     4321 cgctgcgtta gcagtgctgc agcatcgact ccagcgccgt cttctccggc acggtgatcg
     4381 tcaggccgta gttgcgcttc acgacgatcc agtccgtggc gtaggtgcac cagtacgaga
     4441 cgagcggcgg cttccactgg tcgggtgcct tgtcgctctt ctgctcgttg aggttgtcgg
     4501 tgaccgcgtg cagctgcggg cggaccaggt cgttcgcgaa ctgctcgcgg cgctcctggg
     4561 tccacgactt ggcgccgctg acccacgcct gccccagcgg caccatgtgg tcgatgtcca
     4621 catcggacgc cttgtgccag gtctggccgt cgtaggcgct cacccaggtg ccggacttgg
     4681 cggcgcagtc ggagttcgtg gtgacgtcct tgccgtcgcg cttgaggacc tgctcgcggg
     4741 tgtcgcaggc gccctcgacc ttgtcccagt gcggaaactt ctcgcggctg tatccgtcca
     4801 tggtcccgcg cacggcgacc ttcagctgtc ccagctcggc ccgcgcttcg gcgggcgcga
     4861 ccggcgcggc ggcggcggtt ccggtcggct gggccccgga ggccaggtcg tcgggcacct
     4921 tgcagccggt gacggcggca ccggtgagga cggccagcag aacgagcgct tgggtgcgcg
     4981 gcatcgtgaa cccctttcac atctaccggg aggtgcccag ccgacgtcgc ggggaaacgg
     5041 tgcagatggc ctagttggcg cgatctttac gagccgtgga agacctgcgc gacgaacacg
     5101 gcggcgatga cgcctgcggt gacgagcagc gtcagcaccg ccagcaggcc ccagggcacc
     5161 tgccggatcg gccggggccg cgggaagacc gccgaacccg gccgccgggg cagcgggacg
     5221 gccggctcgc cgggttcctc ggcggccggc gggggttcgg ccgggatggg cacgaccgcg
     5281 ggcagctccg gcagccggga gcggtccggc aggcgcaccg ggaacccgtc ggcgaccagc
     5341 gcggaccggg gcggggccag gtgggcgagg gaaagcgcgt agcaggcgtc gaggacgtcg
     5401 tcggccgacc agacggtccg ccagcggttg tgctggacga tgatccggcg caggctccgc
     5461 gggtcggcca ggacgacggc gaccccgggg acggtggcgg gctcgtccca gtgcgcaccc
     5521 ggggcgggca gtccggggac gaccgcgacc aggccggtca cgtaccggcc gccttcgtgc
     5581 ccggcgagcg ctccctgcgc cgccgccacc gccgcgcccg cccgctcccc cgatcccggg
     5641 tcggggccgg gctcgtgcgc cgcgatcacc accacgccgg tgcgggtgaa gaccagggcg
     5701 tcgacgaact cggggcccgg caacgcgatg cccgccagcg ccaggcccgt caggtggtcc
     5761 ggtccccgcc cccaggaacg cagcaactcc acgacgtgct ccgccgcggg cggcagagca
     5821 cgttcggtac cggtgcgctg gagggccacg agcaacgccg gtcactcctc ccacgaaata
     5881 gggcactacg acggtaaaag cccgaccgcc gccgccccag cagccgaacg agtgatcgaa
     5941 caccaccgtg cgtgaccgag ggcatgctgg acgcacccga cgaaggagaa cgccatgggc
     6001 gcacccccac ccgcctacca gggcgccgca ctcgaggtcg accggtcgtt ctaccggcgg
     6061 ctcgccgccg agcccggccg ggtgcgggtc gacgccttcg aaatcccgat ccgctccggc
     6121 cgcgcgtggc gggtgccgaa gggccacctc tgccggctca gcaccgtcga aggcccgcag
     6181 gtcggggacc tcaacctgtg gcacgccgac gacccccgcg aacggttctg ggcggcccgc
     6241 acccgccagc tccagcgcgc gcacgtcagc acgttcgacc ggctgtggtc gacgctgccg
     6301 ttcctgcgcc cgctggccac gatcaccgcc gacaccctcg agcaccacgg cgtggacggc
     6361 gacggcggcc gcgtgcacga cctgctcggc acccgctgcg acccgtacgt caaccggctg
     6421 ctcaccggcg aggacttcga cttccactgc cactcgaacc tggtccgcgc ggtcgcgccg
     6481 ttcgggctca ccgagttcga cgtgcacgac gtcctgaacg tcttccagtg caccgggctc
     6541 accgaagacg accgctactt catgaaggcg tgcccggccc gcccgggcga ccacttcgag
     6601 ttcttcgcgg aggccgacct gctgtgcgcg ctgtcgacgt gcccgggcgg cgacctgtcc
     6661 gtcccgctgt ggggcccgga cgcccgcgac ccgatcgacg tctgccaccc gatcggcgtc
     6721 gaggtgttcg caccgcgcgc cgacctgttg gaaggctggt ccccaccggc gcgcgcggcc
     6781 taccgcgggc tgcacggcgt ccggctgccg gagtgggccg acctgcccga tcggacgggt
     6841 cggcgcggcg aacccgcggg gtagcctggc cggaagtcga cggcgttccg actccgaggg
     6901 cctcaccatc gcgaagttcc acgctcgtcg ctcttgccga agcctcctcg agcgggaacg
     6961 gcttggtcgg ttcgccgacc tgcacggggc gtcccgctcc cgaacgggct cagtgcgagc
     7021 cgacgctctt tgcgttgtgg cgcaagcgat ccggcgtacc cggaaaccgt ccggccgggg
     7081 cgggcgggca ccggcccggt cggaaaggtt cacctggcgg ccggtccgtg tgatgatggc
     7141 aggccgggta caccgatcgg gtcgctcgag gagtgcgcgt ggacctgcgg accgagatcg
     7201 cgcagtcgtg gcggcgggcg gagctctccg ggctctcgcc ggcgtccgcc atcgaccggc
     7261 tcgacgtcgc cgacgtcgac agccgcagcc ggttgctgcg ggccgcttcg cccgtgctcg
     7321 acgagctggc ccggcagctg gccggcacgc ggttctgcgt cgtgctcgcc gacgacgagt
     7381 gccgcatcgt cgcgcggcgg ttcaccgagc ggtcggtgga gctggcgctg gagaacgtca
     7441 gcgcggtgcc cggctgccag ttcatcgagg agcggacggg aacgaactcc ctcgccacgc
     7501 cgttcgagac ccgccgcggt gtctccgtcg acggtgacga gcacttcctc gaagccatga
     7561 agcagttcac ctgctacggc cacccgctgg tgcacccttc gacgcggcgg ctggccggcg
     7621 tcctcgacat caccgggccg gccggcgacg cgaacccgct gctcgggccg ttcctgcggc
     7681 gcgcggtcgc cgacatcgaa cggcggctgc tcgacggcgc gaagctcgcc gagcagcagt
     7741 tgctggccgc gttccagtcg gtgcagcacc gggcctgtgc ggtgctggcg ctcggccagg
     7801 acgtcgtgct ggccaacacg gcggcgaccg agctggtcga caccgccgac caccggctgc
     7861 tgcaggacct cgggcgcacc cagcgggggc tccggcgcat ccggctgacc tccggcacgc
     7921 cggtggaggt gcgcgtcgaa gccgtgtcgg cgaacgccgg gctgctgttc gagctggcgc
     7981 cggtgcgccc ggcgagcccg gtggtgtcgc gcccgcgcgc cgcgcgcggg ctcttcccgg
     8041 cgccgatcga agaccgcctc caccgcgccg gccacgcccg gcggcgggtg ctcgtctgcg
     8101 gcgagcccgg cgcgggccgc agcacggcgg cccgggtgat cgccggggac gagccggtgc
     8161 gcgagttcga cgcgtccgac gtcgtcgcgg gcgaagccga ctggtgcgct cgcgtggagg
     8221 cggcggcgag ctcccgtggc ctgctggtga tcgacgggat ccagctgctg cccccgctcg
     8281 cggcagtccg cctggcccgc ctgctggacg agtcaccggc gtggttcgcc ctgctcagcg
     8341 gcccgccgtc ggagctgcac ggcgagcagg cgaccctggc ggcacgcgtc caccgccgga
     8401 tcgagctgcc cccgctgcgc gagcgccgcg acgagatccc ggcgatcgcc cgcgagctgc
     8461 tacgcggctt cggtgcttcg ctgcgcctga cgccgggcgc gctggagctg ctggcgtccc
     8521 agcactggcc gggcaacctg cgcgagctgg agggcgtcct ggcggcggcg gccgaccgcc
     8581 gctcggccgg cgacctgacg gcggccgacc tggccccgga ctgcacggag acgggcgggg
     8641 ccctgaccgg ctgggagcag gccgagtacg acgtcatcgt ccgcacgctg cgagcctgcg
     8701 acggcaacaa ggtgcgggcg gcgaagcagc tgggcatcag ccgctcgacg ctctacaacc
     8761 gcatgcgcgc gctgcgggtc cgctgagagg ggtgtccggg attcggacac cccacggccg
     8821 cggccgctgc tcacaatcga cgggcgagga cgcacgccgc acgtcaagga gatggccgtg
     8881 aagacgaagg cagccgtact gttcgatgcc gggaagccgt tcgagatcat ggagctcgac
     8941 ctcgacgggc ccggtcccgg tgaggtgctc atcaagtaca ccgccgccgg gttgtgccac
     9001 tcggatctgc acctgatcga caacgacctg gtgccgcggt tcccgatcat cggcgggcac
     9061 gagggcgccg gggtcatcga agaggtcggc cccggtgtca ccaaggtcgc gcccggcgac
     9121 cacgtcgtgt gcagcttcat cccgaactgc ggtacctgcc gctactgctc gaccggccgc
     9181 cagaacctct gcgacatggg cgccaccatc ctcgacggcc acctgcccga cggcaccttc
     9241 cgcttccacg gcggcggcca ggacttcggc gcgatgtgca tgctcggcac gttctccgag
     9301 cgcgccacca tctcgcagca ctcggtggtc aaggtcgacg actggctgcc gctggagacc
     9361 gcggtcctgg tcggctgcgg cgtgcccacc gggtgggcca ccgccaacta cgccggcggg
     9421 gtccgcgccg gggacaccac cgtcgtctac gggatcggcg gcatcgggat caacgccgtg
     9481 cagggtgccg cgcacgccgg ggcgaagtac gtcgtcgcgg tcgatcccgt cgagttcaag
     9541 cgggaggctg cgctcaagtt cggcgccacc cacgcgttcg ccaccgcggc cgaagccgcc
     9601 gagaaggtca acgagctcac ctggggccag ctggccgacc aggcgctgat caccgtcggc
     9661 accgtggagg aggacgtcgt cagcgaagcg ttcaacgtcg tcggcaaggg cggcaccgtc
     9721 gtcatcaccg ggctcgccaa ccccgagaag ctcaccgtgc acgtctccgg cggcgtcatg
     9781 acgctgttcg agaagacgat caagggcacg ctgttcggct cggcgaaccc gcagtacgac
     9841 atcgtccggc tgctgcggct ctacgacgcc gggaagctca agctcgacga gctggtcacc
     9901 cgcaagtaca ccctcgagca ggtcaacgag ggctatcagg acctgcgcga cgggaagaac
     9961 atccgcggcg tgatcgtcca cgcgtagcgg ggggtccaca atggacctcg acgcgccgta
    10021 ccgggtgaac ccccacgagc ccttcgaggt gctcgtccac cgctgcgagc accgggacgg
    10081 gtgcctgctc gggactcccg acgtggtccg cttcgtccgg gcgctggcga tgcacgccac
    10141 ggcgcgcgac gcgatcgacg ccgccgagct cggcgagacc acgcgggccc gggtggtggc
    10201 ggcgctcgaa cacctcgccg ccaccggcgt catcgtcgcc gagccgtgaa acccccggtg
    10261 gccaccgcga tcccgacgcg gtggccaccg gctccacagg taccaaggca agcatcgacg
    10321 acatctgcca tgtcagcctc accgccgaac ttctcgactc gaggacgccg gccccagatc
    10381 agcggtgcgg gcgcatgccg cggccaactt ctgccgccag ggctctttcg cgaacgcggg
    10441 cagacgccgc ttgagggtcg cgtacgccga cctgcctcct cgaccacccg cagactgtcc
    10501 agcttgctgg tcggctcgac gatccttgcc agcaccagta atcggaacac ctcgtcacca
    10561 ccagcagcct cctccaaccc ccacagctgg taggcgtggc cgagcgcgtc ccacaggtac
    10621 tccatccgcg acgacgtgat cgcaagcggc ccaccaccgg cctgcaacgc cgctgcctcg
    10681 ccaccgccgt gagcgcctcc aacgccgcat cgtcatgcgc cgagccgatg tgctcgatgt
    10741 cccgcgaccc gcggagaaca cgatctgcac cgcagatctt cgccgttcac acgacgaaac
    10801 cgcagctcaa cagccggcac cctacccaag atcagcgatc ttgagccaaa ggcaggtaag
    10861 gtgacggaat ggtcatgcgg gtggcgattc ccgtgctgcc gtgccgagat gtgcaggcag
    10921 cgcggtcgta cttcacggac gtgctcggat tcgacaccat attcacctgg gagaccccac
    10981 ccagctacgc ggccgtgatc cgcgacaccg ccgagttcca cctgtacgcc gaaagcagcg
    11041 tcggcccggc cagggtgacg gttgtcgtcg acgacgtcga ttcctgccac gacgagctgc
    11101 gcgcccgcgg tgccgacatc gtcgagccac tggccgaccg gccctacggg atgcgcgact
    11161 tcaacgtacg gacacccgat gggcacttgt tgatcttcag ccagccgctt acctagtacg
    11221 ggtgaccatc agcggaccag ccggaagaat gaccggacct cgtcgacgaa caacgccggc
    11281 tgctcgaacg ccgcgaagtg gccgcccttg ccgggctcgt tccagtaccg gatgttcggg
    11341 aaccggcgct ccgcccaccg ccgagacggg cgctgcattt tttggggaag accggacagc
    11401 cggtgggtac ggtcaccagc gcgccggccg gcccggagat ccattcgttg acctgccgga
    11461 ggctttccca gtacagccgg gcggatatcc gctcgatccc ccacccaggc gcggccggct
    11521 tgtcgctgaa gccgtaaccg ggaagcgatg ggcagacccc taggaccggc cacttagtgc
    11581 gcagagccaa gtcaggttgc ctggtggcaa ccgattcccg cctgcgtcta tgacagtcgg
    11641 acagcactcc tgggtcacgg gcgcggggcg ttgcgcaggt tggcgcgcgc caggtcgacc
    11701 atcttgccga cgccgccgtt gagcaccgtc ttcgtcgcgc ccaaggcgaa gccgcgcacc
    11761 atctcgccgg tgatccgcgg cgggatcgac agcgcgttcg ggtcggtcac cacctcgacg
    11821 accgccgggc cggggtgggc gaacgccttc tccagcgcgc cgcggacgtc ggccgggtcc
    11881 tcgacccgct cggcgaagac gccgcacgcg gccgcgatcg ccgcgaagtt caccggcgcg
    11941 tggtcggtgc cgaagtccgg gagcccgtcg accagcatct ccagcttcac catgccgagc
    12001 gtggcgttgt tgaacaccac gaccttcacc ggcacttcgt aggccggcag cgtcagcagg
    12061 tcgcccatca gcatggcgag cccgccgtca cccgagagcg acacgacctg gcggcccggc
    12121 tgggacagct gcgcgccgat cgcgtgcggg agcgcgttcg ccatgctgcc gtgccggaac
    12181 gagccgagca cgcggcggcg gccgttgggg gtcaggtagc gcgcggccca gacgttgccc
    12241 atgccggtgt cgacggtgaa cacggcgtcg tccgcggcga cctcgtcgag caccgaagcg
    12301 acgtactccg ggtggatcgg acggcgctgc tcgatcttgc ccgtgtacgc gccgacgacc
    12361 ttctccagct tccgcacgtg ctcgcgcagc atccggtcca ggtacgcgcg ctcggtccgc
    12421 gggcgcagca gcggcagcag cgcgcgcagc gtctccttga cgtcgccgtg caccgccaag
    12481 tccagcggcg tgcggcggcc gaggcgcgaa gcgtcgtggt cgacctggat cgtgcgcgcc
    12541 tgcgggagga acttgtcgta cgggaagtcc gtgcccagca acacgatccg gtcggcttcg
    12601 tgcatggcgt cgtagcaggc gccgtagccg agcaggccgc tcatgccgac gtcgaacggg
    12661 ttgtcgtact ggatccactc cttgccgccg agcgagtgcc cgaccggggc ggctagtttt
    12721 tccgccaggg ccatgacttc ttcgtgcgcg ccgcggacgc ccgcgcccgc gaacagcatc
    12781 actttctccc ccgagttcag caggtcggcg agcttctgca cggcgtccgc ggacggcacc
    12841 ggcggcgacg gctcgaccag cgggagccgc tcggtgagcg ggccggtggc cttgcggtcg
    12901 gcgaggtcgc ccgggatggt cagcaccgcg acgccgccct tgccgacggc ggcctgggtg
    12961 gcgatgcgca acagccgcgg cagctgcgcc gggtccgcga cgacctcgct gaagtggctg
    13021 cactccgtga agaggcggtc cgggtgggtc tcctggaaga acccggtgcc gatctggttg
    13081 gacgggatgt gcgacgcgat cgcgagcacc ggcgcgcccg agcggtgggc gtcgaacagg
    13141 ccgttgatca ggtgcaggtt gcccggcccg cagctgcccg cgcacaccgc gagcttgccg
    13201 gtgacctgcg cttcggccgc cgcggcgaag gcggcggtct cttcgtggcg gacgtgcacc
    13261 cactcgatgc cgtcgatgcg gcgcacggcg tcgacgatcg ggttcaagct gtcgccgacg
    13321 atgccgtaga tgcgctcgac gcccgcgtcc cgcagcgtcc tgaccagttg ttctgccacc
    13381 gtagccatgc ccccagcctg ccccgccccg gcgcatgcgt ccaatgcctg atcggctgaa
    13441 cttccataca ctgggcgcat ggacgtccag atgctgcggc tcttccgcga ggtcgccggc
    13501 ggcgcgaccg tcacggagac cgcggccggg gcccacctga cccagcccgc gctctcccgg
    13561 gccctgcggc ggctggagca cgaagccggc gccgagctgt tccgccggtc cgggcggctg
    13621 ctgcggctga cgccggccgg gcacgtcttc aagcggcacg ccggcctcgt gctcgaccag
    13681 ctcgaccagg gcctgcgcga agtcgccgac atcgtcgcgc cgggggccgg cgtcgtgccg
    13741 ctggccttcc tgcacacctt cggcacctgg ctcgtgcccg acgtcctgag cggcttcctg
    13801 cgcgagcacg cgagcacccg cttcgagctg cggcagcacg gcgaggccgg gctcgaggcg
    13861 gagttgctcg agggcaccgc ggacctcgtc ctcaccagcg gcgaccccgg gcacccccag
    13921 ctgcactggg aacgcctgct cgtcgagccg ttgcggctgg ccgtcccgcc gcaccaccgc
    13981 ctcgccgggc gacaccgcgt ccgcctcgcc gacgtcgcgg acgagacgtt catcctgctg
    14041 cgccccggtt acgcgctgcg cgaaacgacc gagcggctgt gcgccgaggc cgggttcgcc
    14101 ccgcgcatcg ggttcgaggg cgacgaagtc gagacgctgc gcgggctcgt gaccgccggg
    14161 ctcggcgtgt ccgtgctgcc gctgccgcac acggcggcgt tcccggcgcc gcacctggaa
    14221 ctgaccgatg tggacgctgc ccgcgacatc gggctcgcgt gggtggccgg gcggaacctc
    14281 cccgcaccca gcgaaacctt ccggcggcac gtgctcgaca ccgttcccgg gcggttcgac
    14341 cgtccacaag ggaccatgtg agaatcgccg tacgaccacg caaagtgacc gccggtgtga
    14401 cagggtggag acatggccgc gctgagatcc ttcctgacgt cctggacctc cgtcaccccc
    14461 gtgctcggca tcctcgtgct cgcgctcgcc tggggccgcg acctcggccc ggtcttcgtg
    14521 gcgatcgtgg cgatcgcgct cggggcgacc gtgctggccg cggtgcacca cgcggaggtc
    14581 gtcgcgcacc gcgtcgggga gccgttcggc tcgctcgtgc tcgcggtcgc ggtcaccgtc
    14641 atcgaagtcg cgctgatcgt cacgatgatg gtctcgggcg gcccggacgc cggctcgctg
    14701 gcgcgcgaca ccgtgttcgc ggcggtgatg atcacgacca acggcatcgt cggcatctcg
    14761 ctcctggtcg gcgcccgccg ctacggcgtc accctcttca actccgaagg cagcggtgcc
    14821 gcgctggcca cggtcgcgac gctggccacg ctgagcctgg tgctgccgac gttcacctcc
    14881 agcacgccgg gcccggcgtt ttcctcggcg cagctgacgt tcgccgccgt cgcgtccctg
    14941 gcgctgtacg ccacgttcgt gctgacgcag accatgcgcc accgcgactt cttcctcccg
    15001 gtggcggccg acggcgaggt caaggaagac gaccacgccg agcccccgac gaaccgggcg
    15061 gcgctgggca gcctcgcgct cctgctgatc gccctggtcg cggtggtcgg cctggcgaag
    15121 gtggagtccc cggcgatcga ggcgggcgtc cgcgcggccg gcttcccgca gtcgttcgtc
    15181 ggcgtggtga tcgccctgct ggtcctgctc ccggagacgc tcgcggccac gcgcgccgcc
    15241 cagcgcgacc ggatgcagat cagcctgaac ctcgcttacg gctcggcgat cgcgagcatc
    15301 ggcctgacga tcccggcgat cgcactggcg tcgctgtggc tgccgggcga gctgctgctg
    15361 ggcctcggct cgacgcagat cgtgctgctg gcgttgacgg tggtggtgag cgtcctgacg
    15421 gtggtcccgg gccgggcgac ccgcctccag ggcggcgtgc acctggtgct gctggcgggc
    15481 ttcctggtgc tggccgtcaa cccctgagag cccccggtcg tgagtgggaa acagcgttgg
    15541 aacaccgttt cccactcatg agctcgccga ccggacctcg atccccacca cgcacgtgtc
    15601 gtcgtcggtg tccgccgtgc tgtaggtcag cagtgtgtcc agctggtgct ccaagccacc
    15661 ctcgtggcgc tccaccaggg tcaccagccg cgagaccgtc tcctggaccg ggcggtcgcg
    15721 gcgctcgatc aagccgtccg tgtagatcag caggatgtcg ccctccgcca ggcggatctc
    15781 ctcctcctgg tacgtcacgt cccggaccgc gcccaggagc gagccgcgga tcagcggcag
    15841 ggtcgtcacc tcgccgtcgc ggtggcggac gatcgggggc aggtgtcccg cgcgcgccca
    15901 gcgcaacgcc cgggtcgccg ggtcgtacac cgccgcgacc gcggtcgccg tcacgtggtc
    15961 ggtgaggtgg taggcgacca ggttcagcca ggtcagcagc tgcgccgggc cggcgcccgt
    16021 cgccgcgagg ccccggagcg cgttgcggag gctcaccatg cccgtcgccg cgtcgatgcc
    16081 gtggccggcg acgtcgccga cgcacagcag cacctcgccg gtcggcagcg cgaccgcgtc
    16141 gtaccagtcg ccgccgacca ggtgctcctt ctcggccggc cggtagcgga cggccgcgcg
    16201 caggcccggc atgtcgatcg gccccttggc cggcggcatg atcgcgtgct gcagctgtag
    16261 cgcgagccgg ttgcgctcga tcgactgctg ctcggtctcg gccagcttgt cccgcgtcgc
    16321 cgcgagtgcc acctcggtcc agtgctgcga cgagacgtcc tggtaggcgc cgcgcacggc
    16381 gagcagctcg ccggccgcgt cggcgaccgg ctcggcgacc acccggatgt gccgggcgac
    16441 gccgtcggag cgctgcagcc ggaacgccgt cgaggacggg cgctggtggt gcagcaccgc
    16501 ccgcaggaac cggccgatcg ccggcccgtc gtcggggtgc gcgtgcgtgg ccagttcgtg
    16561 cagcgacagc ggcgtggcgg tcggcggcag gccgtacagc gcgaacagct cggtgttcca
    16621 ggtgatcgtc ccggtcacga cgttctcctc gaacccgccg atccggccga gccgctgggc
    16681 gtgctgcagc agcacggcga gcttcgccgc gtcgtcctgg atgcgcagga tgagcagcac
    16741 gttgccggcg aaccgggtca cgctcacgtc ggtgtgcacc gtcagcggca cctggtcgac
    16801 gagggtggtg accggcaggc tgcccgcgcg gaacggctcg ccggtcgcgt agacgcggcg
    16861 gatcttgtcg agcaggccgc tctcctcggc cgccagcggg tacgcctcca gcaggcgggt
    16921 gccgacgatc cggctgcggg gacggccgcc ggggtcggcg aaccggacgt tggcgtggtg
    16981 gatgcggaag tcggtgagcc ggccgccgtc gacgcagggc gacagcagca ccgccgggtc
    17041 gtgcaggccg tcgacgaagt ccaccagctc gctgaggaag tccccggacc cggcggccac
    17101 cggcgcgacc acgccgtccc acgtgtcgag cgtgtgcccg cacagctcgg ccagcgcctc
    17161 cagctgacgg cgctgccgcc cgggctcggc gggcagcggc tcgggccagc acatctcgac
    17221 gacgccgatg atccggccgc cggtgccggt gggcaccgcg acgcgcccgc cgccggagag
    17281 ggtgtgctgc ccgagcgagg gcagcccggc gccggacagc gtcgggtacc agaccgtgtc
    17341 gcgttcgagc agcgcgttgc gggccggcgt cgccaccccg ggcgggacgt accgccagcg
    17401 ggccgcctct tcggcggaga accccgccga cccggccagc gtgagcgaac cgtccggccc
    17461 ggcgagccac accgcgacgg cggtcgcgcc gagcgggcgc agcgcgtgct ccaggatgga
    17521 ctccgcgacg cgctgggtgt cccccgccgc gagcaccccg ctttccgcgg tgcgcagccg
    17581 caccgcgacg gagtcttcgc cctccgcgcg ggccaggaac tcctgcgcca cttcggtgat
    17641 gcggtcctcg gccgcttcgc cgacgacgtc cgcggcgaac tccagcggcg tcagcccggc
    17701 ccgcccggcg aggctttcca gctgccgggc ggcgtcggcg ggcgtgcagt ggaggcgttc
    17761 catcagcacg cccttggcca gctcgatcag cgcgcggccg tcggcgacgg cgtgcgcgtg
    17821 gtcgacctcg ccgcgcagcc tggcgacggt ctcggcgagc cgggccaggt tggccgacac
    17881 ctcggccggg cgccccggga ccgggagcag ctcttcgtcg gcggtcaccc gatcacgccg
    17941 tcacgtgccg cttgatgcgg gcgatcaggt cgtccgcgtc gaccggcttg gtcacgtagt
    18001 cggtcgcgcc ggaggcgagg ctcttctccc ggtcgcccgg catcgccttg gccgtcaccg
    18061 cgacgatcgg gatggcggcg tgctcgggca tcgcgcggat cttcgcggtc gcggtgtagc
    18121 cgtccatctc cggcatcatc acgtccatca ggatcaggtc gatgccgggg tgggcggcga
    18181 ccgtctcgac gcccttgcgg ccgtcttcgg cgtgcagcac ctgcatcccg tgcagctcca
    18241 ggatcccggt cagcgcgtag acgttgcgcg ggtcgtcgtc gacgatcagc accgtgcgcc
    18301 cggacagcgt ggtgtcgacg tcggccgccc gcaccggcgc ggccggctcg tccgggcgga
    18361 ccagcggcag caccgcgccg ggctcttcgg ccgacaggtg cagggcgatc cgctcgcgca
    18421 gctcgtccag cccggacagc acttcgagcg actggacgtc cgcgcgggac tgcaccagct
    18481 gctccagttc gctgtcgagg cggcggctgt tgtgcgccag caccggcacc agccgcagcg
    18541 cgctgtcgcc ctgcatcgcg tcgaggaacc cgaacgcggt ccggtccggc aggtccaggt
    18601 cgagcaccac gcagtggtag gcgtcggtgg cgagcgcggc cgcggcctcc tgggtgccga
    18661 ccgccgtcac gacttcgacg tcggcgggtg agaggccgat gtcccggctg tcggcgagat
    18721 ccgcggcggc gctctcggcg acgagcgtca gcagcccgtg ctggcgctcc tccacgacga
    18781 gcagccgccg gtacgcgcgc ggcgcggacg tggtgagcgc ggtacccgga tcacccgcca
    18841 cgacgagcgc gccggggtgg tcaccggcgg gcagcgtcgc gaagtccggg cgggcgaccg
    18901 gcagcgagaa ggtgaacgtg ctgccctcgc ccagggtgct ctcggcggtg atgaacccgc
    18961 cgagcagctg ggcgatctcg cggctgatcg acaggccgag cccggtgccg ccgtacttgc
    19021 ggctggtggt gccgtcggcc tgctggaacg cgccgaagat cgattcgagc tggtgctcgg
    19081 cgatcccgat gccggtgtcg gtgacgcgga aggcgacggc ggcgccgtgc gcgcgcagcg
    19141 gccgcggcag cgtttcgacg tcgaccgcct cgatgtgcag ctcgatcccg ccgacctcgg
    19201 tgaacttgac cgcgttggac agcaggttgc gcagcacctg ccgcagccgc gagtcgtcgg
    19261 tgagcagttc gggcggcgag ccgggggcga cggtgatccg gaagtcgaga ttgcgctggg
    19321 aggtcatcgg ccggaacgtc gcctcgacgt agtccagcag gccacgcagc gacacctgct
    19381 ccggcgtgac gtccatcttc ccggcctcga ccttggacag gtcgaggatg tcgttgatca
    19441 gctgcagcag gtccgagccc gcggagtgga tgatcccggc gtactcgacc tgcttggcgg
    19501 tgaggttgcg ggtcgggttc tgcgcgagca gctgggcgag gatgagcagg ctgttgagcg
    19561 gggtgcgcag ctcgtggctc atgttggcca ggaactccga cttgtacttc gacgccagcg
    19621 tcagctgctg ggcgcgggcc tccagctcct ggcgggcctg ctcgatctcc aggttcttcg
    19681 tctcgatgtc gcggttctgc gtgaccagca gcgccgcctt ctcctccagc tcggcgttgg
    19741 acgactggag ctcttcctgg cgtgcctgca gttcttccga gcgggcctgc agctccgcgg
    19801 tcagccgctg ggactccccg agcagctcgt cggtgcgggc gttggcgacg atgctgttga
    19861 cgttgacgcc gatctgctcc atcagcagct cgaggaaccc gcggtgcacc gtggtgaagc
    19921 cgtgcaccga cgccagttcg atgacgccga gcacctggtc ctcgaccacg atcggcagca
    19981 cgaagaggct ggccggcacg gtgctcccga ggccggagga gatggtggcg tagccgggcg
    20041 ggacgtcgtc gacggcgatc gggcggcggc tgcgggccgc ctgcccgacg agcgactggc
    20101 cgatccggaa gcgggccacc gggccctcgc cgtccgggtg gccgtacgcg ccgaccagcc
    20161 gcagctcggg gacctcggcg gtgtcgtcgg ccaggtagaa cgcgccgtac tgggcgttga
    20221 ccagcgggac cagctcgtcc atcaccgcg
//
