LOCUS       NZ_CP095274            22290 bp    DNA     circular CON 08-MAY-2024
DEFINITION  Clavibacter michiganensis subsp. michiganensis strain N.P.
            chromosome, complete genome.
ACCESSION   NZ_CP095274
VERSION     NZ_CP095274.1
KEYWORDS    RefSeq.
SOURCE      Clavibacter michiganensis subsp. michiganensis
  ORGANISM  Clavibacter michiganensis subsp. michiganensis
            Bacteria; Actinomycetota; Actinomycetes; Micrococcales;
            Microbacteriaceae; Clavibacter.
REFERENCE   1  (bases 1 to 3334132)
  AUTHORS   Akhremchuk,A.E., Miamin,V.E. and Valentovich,L.N.
  TITLE     Genomic analysis of Clavibacter michiganensis subsp. michiganensis
            strain N.P
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 3334132)
  AUTHORS   Valentovich,L.N., Akhremchuk,A.E. and Miamin,V.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (07-APR-2022) Center of analytical and genetic engineering
            research, Institute of Microbiology, National Academy of Sciences of
            Belarus, Kuprevich 2, Minsk 220141, Belarus
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: 07-APR-2022
            Assembly Method :: Barapost v. 2021-06-28 edition; Flye v.
            2.9-b1768; canu v. 2.2; SPAdes v. 3.15.2
            Assembly Name                     :: Cm-NP_v1
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 140.0x
            Sequencing Technology :: Illumina MiSeq; Oxford Nanopore MinION
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_022983255.1-RS_2024_05_07
            Annotation Date                   :: 05/07/2024 05:27:08
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,225
            CDSs (total)                      :: 3,170
            Genes (coding)                    :: 3,147
            CDSs (with protein)               :: 3,147
            Genes (RNA)                       :: 55
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 2, 2 (5S, 16S, 23S)
            tRNAs                             :: 45
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 23
            CDSs (without protein)            :: 23
            Pseudo Genes (ambiguous residues) :: 0 of 23
            Pseudo Genes (frameshifted)       :: 5 of 23
            Pseudo Genes (incomplete)         :: 18 of 23
            Pseudo Genes (internal stop)      :: 6 of 23
            Pseudo Genes (multiple problems)  :: 4 of 23
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 06:43:17
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 3124459
            Orig. end                         :: 3146749
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP095274.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            Bacteria and source DNA available from Dr. Vladislav E. Miamin,
            Faculty of Biology, Belarusian State University (Minsk, Kurchatova
            str., 10).
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..22290
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="azole-containing-RiPP"
                     /region_number="10"
                     /rules="((YcaO or TIGR03604) and (((thio_amide and (PF06968
                     or PF04055 or PF07366)) or Lant_dehydr_C or Lant_dehydr_N
                     or (PF06968 or PF04055 or PF07366)) or (goadsporin_like or
                     PF00881 or TIGR03605)) or TIGR03882 or TIGR03603 or
                     thiostrepton or TIGR03602)"
                     /tool="antismash"
     cand_cluster    1..22290
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="((YcaO or TIGR03604) and (((thio_amide
                     and (PF06968 or PF04055 or PF07366)) or Lant_dehydr_C or
                     Lant_dehydr_N or (PF06968 or PF04055 or PF07366)) or
                     (goadsporin_like or PF00881 or TIGR03605)) or TIGR03882 or
                     TIGR03603 or thiostrepton or TIGR03602)"
                     /kind="single"
                     /product="azole-containing-RiPP"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..22290
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:12290](-)"
                     /cutoff="10000"
                     /detection_rule="((YcaO or TIGR03604) and (((thio_amide and
                     (PF06968 or PF04055 or PF07366)) or Lant_dehydr_C or
                     Lant_dehydr_N or (PF06968 or PF04055 or PF07366)) or
                     (goadsporin_like or PF00881 or TIGR03605)) or TIGR03882 or
                     TIGR03603 or thiostrepton or TIGR03602)"
                     /neighbourhood="10000"
                     /product="azole-containing-RiPP"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..12290)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="((YcaO or TIGR03604) and (((thio_amide and
                     (PF06968 or PF04055 or PF07366)) or Lant_dehydr_C or
                     Lant_dehydr_N or (PF06968 or PF04055 or PF07366)) or
                     (goadsporin_like or PF00881 or TIGR03605)) or TIGR03882 or
                     TIGR03603 or thiostrepton or TIGR03602)"
                     /neighbourhood="10000"
                     /product="azole-containing-RiPP"
                     /protocluster_number="1"
     misc_feature    complement(319..330)
                     /note="TFBS match to AfsR, Pleiotropic regulatory for
                     antibiotic production, confidence: medium, score: 18.46"
                     /tool="antismash"
     misc_feature    complement(461..475)
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: weak, score: 18.66"
                     /tool="antismash"
     gene            complement(654..1196)
                     /locus_tag="MU580_RS14665"
                     /old_locus_tag="MU580_14665"
     CDS             complement(654..1196)
                     /EC_number="2.3.1.1"
                     /GO_function="GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA]"
                     /GO_process="GO:0006526 - arginine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /function="N-acetylglutamate synthase and related
                     acetyltransferases"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015491332.1"
                     /locus_tag="MU580_RS14665"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MU580_14665"
                     /product="amino-acid N-acetyltransferase"
                     /protein_id="WP_012039452.1"
                     /transl_table=11
                     /translation="MSAEPVTAESVEPAAGIRVRRARTGDVPRIQQLVEPLVMEGILLG
                     KDLVVLYENVQEFRVAVDASGEVVGCGALHVMWEDLGEIRTLAAAPHTRGTGVGHALLE
                     RLEDDARELGLSRLFCLTFEVGFFSRHGYHEVAESIIAQEIYYEMLRSHDEGIAEFLDL
                     SRVKPNTLGNTRMLKAL"
     gene            complement(1248..1508)
                     /locus_tag="MU580_RS14670"
                     /old_locus_tag="MU580_14670"
     CDS             complement(1248..1508)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012039453.1"
                     /locus_tag="MU580_RS14670"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MU580_14670"
                     /product="hypothetical protein"
                     /protein_id="WP_086507789.1"
                     /transl_table=11
                     /translation="MDPVRRLMFWLRVPFVADAALVVIGVALLVAGDGVGWWVLVFAGL
                     RAVVGVVAIVWIAPRMIARLASPAPGAGAEPPAPDAGSARR"
     gene            complement(1510..3186)
                     /locus_tag="MU580_RS14675"
                     /old_locus_tag="MU580_14675"
     CDS             complement(1510..3186)
                     /GO_function="GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA]"
                     /GO_function="GO:0004673 - protein histidine kinase
                     activity [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_process="GO:0007165 - signal transduction [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1003: sensor
                     histidine kinase"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012039454.1"
                     /locus_tag="MU580_RS14675"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MU580_14675"
                     /product="HAMP domain-containing sensor histidine kinase"
                     /protein_id="WP_086507790.1"
                     /transl_table=11
                     /translation="MTQPQAATPPGTTPLRATPLRARLTAAARGMTLRRRLVLSVVGLL
                     ALASILIGTVSILALRASLVQEVDQQLQATAARSSNLIDRDADQYGSFPGAPPGGLGAF
                     GQQVGTISATIVDGVVSGGYIADRDAAEGEPGGAGAVELTQVQSQQLQSVPTDGIPRTV
                     DLGGALGRYRLVGDTAATGATLVTGLPMKPADDVVEQLIVVISVVAALTLALAAVLGAV
                     IVRRALRPLDRVVDTATHVAALELDRGDVALEARVPASDTDERTEVGRVGAALNGLLGH
                     VAAALSSRQASEAKVRRFVSDASHELRTPLASIRGYAELTRRGPHQLPEDVTHSLSRIE
                     SESVRMTTIVEDLLLLARLDEGRELESDPVDLTRILLDTVGDASAAGPDHDWDLDLPDD
                     SVSVPGDDARLRQVVVNLLANARTHTPAGTRVVASLAVEGAGSDAHAVIRVTDDGPGIP
                     PAMQENLFERFVRGDGSRARSTGGTGLGLAIAQAIVSAHHGAVWVESEPGRTVFGVRLP
                     VARRAVDARSESGAPAGSASDRWAPPSGAPVADRPGPVGGS"
     gene            complement(3183..3956)
                     /locus_tag="MU580_RS14680"
                     /old_locus_tag="MU580_14680"
     CDS             complement(3183..3956)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /function="Response regulators consisting of a CheY-like
                     receiver domain and a winged-helix DNA-binding domain"
                     /gene_functions="regulatory (smcogs) SMCOG1008: response
                     regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015491335.1"
                     /locus_tag="MU580_RS14680"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MU580_14680"
                     /product="response regulator transcription factor"
                     /protein_id="WP_012039455.1"
                     /transl_table=11
                     /translation="MMDPVTTTPPSGFQPAAAPQPRLTRADGSPIRVLVVDDEASLTDL
                     LQMALRYEGWQIRTAENGHQALAAAREFKPDAVVLDIMLPDLDGLQVLSRLRADAEDIP
                     VLFLTAKDSLDDRLAGLTAGGDDYVTKPFSLEEVVARLRGLIRRSTLVVSDSVDPVIRV
                     GDLTLDEDSHEVARAGDPIELTATEFELLRYLMRNPRRVLSKLQILDRVWSYDFGGKSS
                     VVEIYISYLRRKIDAGRNPMIHTVRGSGYMLKAAE"
     gene            complement(4027..4800)
                     /locus_tag="MU580_RS14685"
                     /old_locus_tag="MU580_14685"
     CDS             complement(4027..4800)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015491336.1"
                     /locus_tag="MU580_RS14685"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MU580_14685"
                     /product="tetratricopeptide repeat protein"
                     /protein_id="WP_246929890.1"
                     /transl_table=11
                     /translation="MPDDPDAPTRARLLWDEHDRAAALALLKDHLREDPRDGDARLALA
                     EMYRELIAPDQAGRWGIAVPGWTTEVERDRLARMIAHSGIADHEIPGFLALPADGERSV
                     EVEALMPAIERHRADFADPARMTKRERKAARYASTPSSFAYEVADVAADLAWWVIGIVF
                     ALGALLVWVAALCGQPVTALARWTGTATLATTALVCLARAYTMRTEELVRRTREPDTAP
                     VDVDVLPWISGAILLGLVVVALVSEGVRSGDPFPF"
     misc_feature    4909..4926
                     /note="TFBS match to HipB, Bacterial antitoxin HipB,
                     confidence: weak, score: 18.77"
                     /tool="antismash"
     gene            complement(4929..5957)
                     /locus_tag="MU580_RS14690"
                     /old_locus_tag="MU580_14690"
     CDS             complement(4929..5957)
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012039457.1"
                     /locus_tag="MU580_RS14690"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MU580_14690"
                     /product="TerC family protein"
                     /protein_id="WP_246929892.1"
                     /transl_table=11
                     /translation="MNITTTTWLITIAVTIAFFVYEFFTHVRKPHEPTIGESARWSAFY
                     IGLALIFGVGIGFTSGWDFGGQYFAGYLTEKALSIDNLFVFLLIMTGFAVPRKYQQKVL
                     MIGIVIALIMRAGFIALGAALIENFSWVFYIFGALLFVLAYQQLKGDHGGNAADNMFVR
                     IARRILPVHDEFVGDRFTTKIDGKRFVTPLLLCVIAIGFVDLVFALDSIPAIYGLTNEA
                     YIVFTANAFALMGLRQLYFLIGGLLERLVYLSQGLAVILAFIGAKLVLHAMHVNELPFI
                     NGGEPMLWAPEIPIWFSLLFIGATITVATVASLAKTRGDKQKGDRKTVEGETVTRATED
                     KH"
     gene            complement(6142..7080)
                     /locus_tag="MU580_RS14695"
                     /old_locus_tag="MU580_14695"
     CDS             complement(6142..7080)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015491338.1"
                     /locus_tag="MU580_RS14695"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MU580_14695"
                     /product="PD40 domain-containing protein"
                     /protein_id="WP_086506627.1"
                     /transl_table=11
                     /translation="MTLRDGQLARLLVVDVETGAERMVAESAVLHIEAPNWTPDGRWLV
                     VNAEGGLWRLPAPDAEEPDPDLPEPAVDFQAVDLGGVPPINNDHVMSPDGAHVYVSGRD
                     GHLYDVLWNDGAGGQGRRITADRDPALGFKNYLHGVSPDGSMLSVIGGQLDARGEWTTN
                     IHLVPVDGGPTTQLTDDGFPDDGAEFSPDGGWLYFNSERGSDLPGHAQLFTMRTDGTDT
                     HQFTSDERVNWFPHPSPDGEHIVYLSFPPGTLGHPADHDVILRVIDRQSHRTRDLAAFP
                     GGQGTINVTSWAPDSRRFAYVAYPFEAPSLT"
     gene            complement(7077..8150)
                     /locus_tag="MU580_RS14700"
                     /old_locus_tag="MU580_14700"
     CDS             complement(7077..8150)
                     /GO_function="GO:0016853 - isomerase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012039459.1"
                     /locus_tag="MU580_RS14700"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MU580_14700"
                     /product="sugar phosphate isomerase/epimerase"
                     /protein_id="WP_086506628.1"
                     /transl_table=11
                     /translation="MPQITTPVALFTGQWADLPLEEVARLASGWGFDALEIACSAEHLD
                     VWRAAEDPAYLRGRLEILERHGLQVHALSQHLTGQAVCDDPIDFRHQAILRSKVWGDGQ
                     AEGVRQRAAEELKLTAKAAAALGVTRVTGFTGSRIWPYVAMFPPVPESVIDAGYQDFAD
                     RWNPIIDVFDDEGVRYALEVHPSEIAYDYWTTRRTLEAIGHRPGFGLNWDPSHMMWQGI
                     DPVGFLLDFADRIYHVHAKDTRVTSDGRGGRLGSHLPWGNPRRGWDFVSVGHGDVPFER
                     AFRALRSIGYDGPVSVEWEDAGMDRLHGAPDALARVRSLLWPTPDSLFDSAFANNRDDA
                     PAATSADGSTGTAGSTA"
     gene            complement(8273..9055)
                     /locus_tag="MU580_RS14705"
                     /old_locus_tag="MU580_14705"
     CDS             complement(8273..9055)
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012039460.1"
                     /locus_tag="MU580_RS14705"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MU580_14705"
                     /product="ABC transporter permease"
                     /protein_id="WP_160478196.1"
                     /transl_table=11
                     /translation="MTAAPMPVRPTAARRFAVYRAHVVSELAQNARMPAFVLPLLAYPV
                     LIYAVVGLPQGGPPSARLSVLLGYVLFSVLGTVTFQFGVGVASARESPWERWLFTAPVP
                     AWIRLAAKLTVACVFGVVFVIPVVAVGILAGGVRVDAATLGSVALAVLAGAVPMALLGL
                     AMGYWFPARGALGLANLVYLPLSFAGGLFTGGDTSGTPWESLTVLLPTGAWSTLTSAAA
                     RQDTAVMGIPLILLAAWTVLLGGITLAGYQRTQSANFR"
     gene            complement(9052..10008)
                     /locus_tag="MU580_RS14710"
                     /old_locus_tag="MU580_14710"
     CDS             complement(9052..10008)
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012297989.1"
                     /locus_tag="MU580_RS14710"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MU580_14710"
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_246929893.1"
                     /transl_table=11
                     /translation="MTDAIELEGITRAFGRTRALDAASFSLAPGLVHALLGPNGSGKTT
                     AIDVLTATRRPDAGRARVLGHDVRRGGPTAALVAVMPQALAFPEYLTVREVLALALVPH
                     AAALTPAAAIDRFDLDRLASRQTGGLSGGERRRVALACVVGAGTPVVVLDEPSAALDIP
                     GRAAVRDAIAAVRDSGRTVLLASHDMEEVAALADTVVCLDHGRVVGHWTAADFRGLAGV
                     RRVGFDATVAEARRLRSSGAVPEAGEEPRGPERIRWVIDTDRSDVVAGLVLAAVPQPRL
                     TVVEPGLGEIVERVLAGGADAIPADPSRTEDHAGCAR"
     gene            complement(10001..10969)
                     /locus_tag="MU580_RS14715"
                     /old_locus_tag="MU580_14715"
     CDS             complement(10001..10969)
                     /codon_start=1
                     /function="Nitroreductase"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     azole-containing-RiPP: PF00881"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015491342.1"
                     /locus_tag="MU580_RS14715"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MU580_14715"
                     /product="SagB/ThcOx family dehydrogenase"
                     /protein_id="WP_012039462.1"
                     /sec_met_domain="PF00881 (E-value: 8.3e-16, bitscore: 56.0,
                     seeds: 78, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSTIETDATPERAEAATGPSARADPATLASGRSLGSVGPIFSVGG
                     AVDRPAGDPAEDFHEASKITRITHPGWTDVRYAHQMAQEAQGITDAGPGGATSAPRLLP
                     ALPLPRALPLRHELGATLAARRSAEPRTLGRPVELAELATVLRLAYGPRGDGTPGRFVP
                     SGGGLYPLDLHVVARSVVGLEPGIHQLDPLEETLVDVSGLDRDGRLARFRRAAPSLMAP
                     IPETAAVTVVITGSFERSRCKYGLRGYRLTLLEAGHVGQNALLVATALGLPVLGWVGFV
                     DHELDAVLGLDGVTQSSLYAISFGGAEPGARRFAEEEASHD"
     gene            complement(11028..12290)
                     /locus_tag="MU580_RS14720"
                     /old_locus_tag="MU580_14720"
     CDS             complement(11028..12290)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     azole-containing-RiPP: YcaO"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015491343.1"
                     /locus_tag="MU580_RS14720"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MU580_14720"
                     /product="YcaO-like family protein"
                     /protein_id="WP_079534293.1"
                     /sec_met_domain="YcaO (E-value: 1.6e-55, bitscore: 186.6,
                     seeds: 127, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSRGGAGVVSPYTGLVEHAHPMAFTPDAIPDALYSGRSADTGFLT
                     GTESERFSMGPGGSRMEARRSCIGEAVERMSLAGAPGGFRAPLGADARQVGPDAFQRFH
                     PTQREDPAFHYERAQAGDLLTWMPARSLHRGDAVHVPAQMVVFDDPHRADGHREPHVEP
                     ATSSGVAAGPHFGFAAGRAVLELIERDAFQRSWLRGSTPPAFDWRGSSRLTDATLRELE
                     RLEELCGRFGASFTVRVLDAAADVPVLLAVMRSDRIGVAVGCAADFRLDRAILNAVREA
                     LHTHNWCLRLLAEPTIDPEDVVEFEDHIRLHCRPSARPLTAALDGSDERVAAIGGPDSW
                     AEVVAGLDREGIEVLLADITAPEVRAAGFHVVRALSPDLVALDVVHAARFLGHPRLYRR
                     WRDGPAIDGPADLVHVPHPFP"
     gene            complement(12287..13198)
                     /locus_tag="MU580_RS14725"
                     /old_locus_tag="MU580_14725"
     CDS             complement(12287..13198)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012297986.1"
                     /locus_tag="MU580_RS14725"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MU580_14725"
                     /product="TOMM precursor leader peptide-binding protein"
                     /protein_id="WP_079534048.1"
                     /transl_table=11
                     /translation="MDSSTTYSVSPRYAVGEVEDTLHLLGGRELVSLKLPSGDAVSAVS
                     RLLSRPFTRADLDRAFAAHAPAVADLVDELVLRDVVVGSPTGSAGSVPDELAHVLDEAR
                     RNGGDRTGLGPVRDAASPARIALVGDMIPSLLTGLAEALPSAELGDEHDADLVIAVGSR
                     PVLREVGARMHAAGRPWLPVHPFDGRFQLVGPVVVPGEGPCLECVALRWASTTPFAADH
                     AAAADAVAVVPRDPSLDAITAGFAARFAARWIHAHDWLVASTVLVIEPKVMEAEAHAVF
                     RVARCGTCGPRPYAGVASPWRA"
     gene            complement(13209..13421)
                     /locus_tag="MU580_RS14730"
                     /old_locus_tag="MU580_14730"
     CDS             complement(13209..13421)
                     /codon_start=1
                     /function="hypothetical protein"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015491345.1"
                     /locus_tag="MU580_RS14730"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MU580_14730"
                     /product="hypothetical protein"
                     /protein_id="WP_012039465.1"
                     /transl_table=11
                     /translation="MSLLMEPTRTTAPEVAPAAGGEAASDALLAEAFGFTITHRGAEEE
                     LVMGDVTLCCSTTCSSSGSGHQQPR"
     CDS_motif       complement(13254..13421)
                     /prepeptide="leader"
                     /note="peptide class: thiopeptide"
                     /note="predicted sequence:
                     MSLLMEPTRTTAPEVAPAAGGEAASDALLAEAFGFTITHRGAEEELVMGDVTLCCS"
                     /locus_tag="MU580_RS14730_thiopeptide"
                     /aSTool="thiopeptides"
                     /tool="antismash"
     CDS_motif       complement(13209..13253)
                     /prepeptide="core"
                     /locus_tag="MU580_RS14730_thiopeptide"
                     /peptide="thiopeptide"
                     /predicted_class="Type III"
                     /score="6.10"
                     /molecular_weight="1432.5"
                     /monoisotopic_mass="1431.6"
                     /core_sequence="TTCSSSGSGHQQPR"
                     /aSTool="thiopeptides"
                     /tool="antismash"
                     /leader_sequence="MSLLMEPTRTTAPEVAPAAGGEAASDALLAEAFGFTITHRG
                     AEEELVMGDVTLCCS"
                     /leader_location="[13253:13421](-)"
                     /alternative_weights="1450.5"
                     /alternative_weights="1468.5"
                     /alternative_weights="1486.5"
                     /alternative_weights="1504.6"
                     /alternative_weights="1522.6"
                     /alternative_weights="1540.6"
     misc_feature    complement(13415..13425)
                     /note="TFBS match to HypR, L-hydroxyproline utilization
                     repressor, confidence: weak, score: 18.94"
                     /tool="antismash"
     gene            13582..14256
                     /locus_tag="MU580_RS14735"
                     /old_locus_tag="MU580_14735"
     CDS             13582..14256
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015491346.1"
                     /locus_tag="MU580_RS14735"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MU580_14735"
                     /product="YqaJ viral recombinase family protein"
                     /protein_id="WP_227334961.1"
                     /transl_table=11
                     /translation="MTDEMLAFPWEDDLAPAAPAPPPPPPHLTRIVAHSSDRVAWLRAR
                     SFGITATDVARLATDASLQAVALEKLYGSGFGGNRYTDHGREREPEIARWVEAEHGIIP
                     SAHLFHAEGQRRHLATPDGVGLRADGRLELAEIKTTAKPWRSIPRNYLRQIWWQQYVLG
                     AERSLIVWEQHVDFVPVHDIPKWKWIDRDEAEIAALVARANDLIALIVRMANAPAGARG
                     LA"
     gene            14550..15506
                     /locus_tag="MU580_RS14740"
                     /old_locus_tag="MU580_14740"
     CDS             14550..15506
                     /EC_number="1.-.-.-"
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /NRPS_PKS="Domain: PKS_ER (25-313). E-value: 3.4e-41.
                     Score: 133.3. Matches aSDomain:
                     nrpspksdomains_MU580_RS14740_PKS_ER.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ADH_N"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ADH_zinc_N"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1028: crotonyl-CoA reductase / alcohol dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012299881.1"
                     /locus_tag="MU580_RS14740"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MU580_14740"
                     /product="NADP-dependent oxidoreductase"
                     /protein_id="WP_246930885.1"
                     /sec_met_domain="ADH_N (E-value: 8.8e-06, bitscore: 23.1,
                     seeds: 66, tool: rule-based-clusters)"
                     /sec_met_domain="ADH_zinc_N (E-value: 2.3e-15, bitscore:
                     54.3, seeds: 86, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRAVVVTETGGPDVLHVADVPVPHRLDSEVLVKVVAAGVNPIDLR
                     LRAGEPGGPTLGVLPAVLGRDFSGVVVESPYEDHALHPGDEVFGLAMVPRMPGSYAPYI
                     AVPSVSLARKPARLSHVEAAATPVSALTAWGMVVDIGKAHEGQVVLVHAGAGGVGHFAV
                     QFARHFGARVVATGSPRNVDWLAELGADEVIDRSQVRFEDVLADVDVVIDLVGNCTDDT
                     GTRSLQVLRRGGLLVSAPVRGWPTLVQDAAAVGVRATHYEVAPDGQKLAVISRLLESGD
                     IKVYVDEVFDLEDAAEAHRHMESGHARGKVVLNVARG"
     aSDomain        14625..15488
                     /ASF="ER configuration inconclusive"
                     /aSDomain="PKS_ER"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_MU580_RS14740_PKS_ER.1"
                     /evalue="3.40E-41"
                     /label="MU580_RS14740_PKS_ER.1"
                     /locus_tag="MU580_RS14740"
                     /protein_end="313"
                     /protein_start="25"
                     /score="133.3"
                     /tool="antismash"
                     /translation="LDSEVLVKVVAAGVNPIDLRLRAGEPGGPTLGVLPAVLGRDFSGV
                     VVESPYEDHALHPGDEVFGLAMVPRMPGSYAPYIAVPSVSLARKPARLSHVEAAATPVS
                     ALTAWGMVVDIGKAHEGQVVLVHAGAGGVGHFAVQFARHFGARVVATGSPRNVDWLAEL
                     GADEVIDRSQVRFEDVLADVDVVIDLVGNCTDDTGTRSLQVLRRGGLLVSAPVRGWPTL
                     VQDAAAVGVRATHYEVAPDGQKLAVISRLLESGDIKVYVDEVFDLEDAAEAHRHMESGH
                     ARGKVVL"
     CDS_motif       14985..15047
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_MU580_RS14740_0001"
                     /evalue="2.50E-06"
                     /label="PKSI-ER_m5"
                     /locus_tag="MU580_RS14740"
                     /protein_end="166"
                     /protein_start="145"
                     /score="20.0"
                     /tool="antismash"
                     /translation="GQVVLVHAGAGGVGHFAVQFA"
     gene            complement(15581..16792)
                     /locus_tag="MU580_RS14745"
                     /old_locus_tag="MU580_14745"
     CDS             complement(15581..16792)
                     /EC_number="3.1.1.103"
                     /GO_function="GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1053: beta-lactamase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012039468.1"
                     /locus_tag="MU580_RS14745"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MU580_14745"
                     /product="serine hydrolase domain-containing protein"
                     /protein_id="WP_209069520.1"
                     /transl_table=11
                     /translation="MTGAGAAVGAGTRADGVVGWVAPGFEGVRRAFADAVASDVGTGAA
                     LSVRQRGDVVVDLAGGVADDVTGRAWGLDTPSVLFSATKGVMSILVARLVQDGRLRYDQ
                     PVAELWPEYARAGKAGTRVADALAHRAGIAAPRVDWTLSDLVDWDRATALVAAEEPRGE
                     PGTAWAYHAITHGWLTGEIVRRVTGLMPGAWFQALATGPLGVDAWIGIPPEVGERVARM
                     RVGTTLRELTSRQRADVAAGGPDLPLRALTLGGALPLELVGDDAGFSRADVQAAEIPGA
                     GGIGTAHALAAVWSAVVVETAGVRLLDDDTIRLATRPVSGGDEPPAFDVPGPWPRWGMG
                     FQLDSAARRYLGSGSLGHDGAGGQVAFADVEHRVGFAFLTNRMEADDDRGTRIVDALRE
                     ALPR"
     gene            complement(16789..17781)
                     /locus_tag="MU580_RS14750"
                     /old_locus_tag="MU580_14750"
     CDS             complement(16789..17781)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012039469.1"
                     /locus_tag="MU580_RS14750"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MU580_14750"
                     /product="glycosyl hydrolase family 32"
                     /protein_id="WP_227266709.1"
                     /transl_table=11
                     /translation="MAFALPGHWVWDSWTAVDGDTTHLFYLHAPTALGDPDLRHRNAAV
                     GHATSTDLVTWTDHGVVLEHGPAGSPDASATWTGSVTRDPSGLWRMSYTGSVFPRDDAG
                     ANVETVLQATSADLHRWVKASVSALSADPRWYETLADGTWREEAWRDPWVEPDPAGDGW
                     RMLVTARSQAAAPGPDADPLDRGVVGHAVSRDLVTWTAAAPLSAPGAGFAHLEVLQVAE
                     VDGRRVLVFSCAGSDLAGARAGQEGGVFALPLDDDQPFGRPVDIGRARLLHGEGLYAAR
                     IVRTPSGPALLGFEDAGADGSFVGRIPDPVPVRWDAAGLLVAVPAGSAS"
     gene            complement(17781..18605)
                     /locus_tag="MU580_RS14755"
                     /old_locus_tag="MU580_14755"
     CDS             complement(17781..18605)
                     /GO_process="GO:0008643 - carbohydrate transport [Evidence
                     IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /function="ABC-type sugar transport system permease
                     component"
                     /gene_functions="transport (smcogs) SMCOG1069: putative ABC
                     transporter permease protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018189691.1"
                     /locus_tag="MU580_RS14755"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MU580_14755"
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="WP_012039470.1"
                     /transl_table=11
                     /translation="MIVNRTELVVGRILLIAVLVLTLLPFASMLTAALQSPDSLPNGFS
                     WPTPAYWENFVTAFTVGNIGTLMLSSLFIVVMVVPVSLVCATLAGYSLGNLRVPGGKYV
                     LVAMIIGLTIPFEAIIIPLYYQMTGFGLINTRWAVILPLIGLYMPFSVFWMRAHFVGVP
                     RELSEAARVDGASIWQEFRSIQLPLARPALSALGILLFLWTWNQFLLPLVMIDDPSERT
                     MAGALGAFQGQYIDALPLLFAASLIVMLPTVIVYVIFQRQFIAALLQGAVKG"
     gene            complement(18602..19597)
                     /locus_tag="MU580_RS14760"
                     /old_locus_tag="MU580_14760"
     CDS             complement(18602..19597)
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1067: putative ABC
                     transporter permease protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012039471.1"
                     /locus_tag="MU580_RS14760"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MU580_14760"
                     /product="sugar ABC transporter permease"
                     /protein_id="WP_172403675.1"
                     /transl_table=11
                     /translation="MSTTDRTIPAGATATAAVPAGPSTRGGGPGRAPTRRRRLGPEARR
                     TATVGWIMLLPAVAAYAAFVVWPLITAVQYSFYKWNGIGASTFIGLDNYVQIFTDTRLL
                     TPIVNALILVIFFMVIPITAGLALATLLRGMKQGPFASISRTILFLPQIVPLVAAGIAW
                     SWMYAQSGTINSILDAVGLGFLSRSWLADFGTALPAVGLIGSWVLTGLCTVLLLTGMGK
                     IDGSLYEAVRLDGAGFFREFVTITLPGLRQEIAVLVTITVIAALSTFDIIYTTTKGGPG
                     TTTLVPGIEIFRLAFVQSQVGLASAFGVVLLVFVLLLVLPVQRLSRERDR"
     gene            complement(19594..20943)
                     /locus_tag="MU580_RS14765"
                     /old_locus_tag="MU580_14765"
     CDS             complement(19594..20943)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1143: sugar-binding lipoprotein"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012039472.1"
                     /locus_tag="MU580_RS14765"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MU580_14765"
                     /product="extracellular solute-binding protein"
                     /protein_id="WP_246929895.1"
                     /transl_table=11
                     /translation="MSTMRRAGRAAALTAAAAISALALASCAPGSAPVASAPAGDVSTA
                     IPTDDLTIRIQDETGFPVTDELTAEFTKQHPNVKFDITRDSFQNLLANTPRLLASDDAP
                     DLIRLSTLGTTVKDGLLTNLDPYFDAYGWDRFPAGQLAGARMDDQGVRGEGSLWQFGIG
                     YSVTGIYMNQELADQVGITEMPATMDELEADLAKAKDAGVLPIQTGMQDGVGTFILQSL
                     INQQGDKQDLVDWMYNKPGATIQTDAALAGATKFQDWAKAGYLPPDVNAINYTTMVSNF
                     SAGQGLFMWDGNWDAANVEKALGQGGAQFGLVPPVEAGGKHVAMGTGNTFAIPAKSKNA
                     DVVAAFLNWIVTDEKARQIVVDVTGASPGGDPAQALPTAQEGSLIAKALELSAEVGDDD
                     GFVDFMANSTAGIYQGSLQPNEQLLLTDKMTPADFLKATQDFYEQDLAAQ"
     misc_feature    complement(21025..21043)
                     /note="TFBS match to LexA_variant_3, Repressor of DNA
                     damage response, confidence: weak, score: 20.15"
                     /tool="antismash"
     gene            21145..22230
                     /locus_tag="MU580_RS14770"
                     /old_locus_tag="MU580_14770"
     CDS             21145..22230
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1078: LacI family
                     transcription regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012039473.1"
                     /locus_tag="MU580_RS14770"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MU580_14770"
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="WP_246929904.1"
                     /transl_table=11
                     /translation="MRQKRPTLADVARLAGLSPTAASQILNGTPETRFSEDSHRRVLAA
                     AAELGYRPNMGARALRTDRSLTIGFISDVVATTRFASGLIRGALVEAERAGHVVLVLET
                     GGEEAREAEAVSAVLDRQVDGIVFATMRARELVVPDVPASTHVVMLNATSPHHGSSVLP
                     DEEEGGRRAVDLLAAAGHSDGIALLGSDIATERSLFRSETVARRLHGIRAEMAELGLRF
                     AAERSCGDWEPDAGYEAAGAILDAAPGTRAILCLNDRLAFGAYQACQERGIRVGIDVSL
                     VGFDNDELASYLRPGLTTIALPHQEMGREAVRLVLRDAEPGERLVGMPMVERGSIAPVT
                     PADSGTARVAAARMAALAASA"
ORIGIN
        1 gggcgctcct tctcctggca cgtggtggtg gacgaccgct gacgcgacca ctcgaacggc
       61 gacgacgtct gcggcgtgcg tgcggcgagc tcgacctcgg cgtcctccgc gcccgtctgg
      121 cagtcggtcg acttccagta gacgtcggat ccgctcgaga tcgtgaacac ctgcgtggtc
      181 gtcccgaggt tcgcggtgca gggctccatg ccggtgttcg tcacggtgaa ggagagcttc
      241 ggcagcacgc cggccttgta ggacgcggcg tcggtgacgg gggtgacggt cagctggccc
      301 gcggcgcagg atccgtcggc gttcgtctcc gtgccggcgc tcgcgctcgg actggggtcg
      361 ggggcaggct cggcggcggc gtcacccgag tcgccggcgg cggcgtccgc gctgggcgtc
      421 gcgccgggag cggcggtctc ggccgtaccg cggccgaggt tggagacgat gatcaccacg
      481 acggcgatca cggccaccac gacgagcagc gcgagcaggc ggcgacggcg gtacacggcc
      541 gcggacgggc ggtctccggg cgaggtcgag gacatgacca caggctattc gcgggccagg
      601 ccggggcccg gtcggcgcgc ccgggcgcgc ggccccgcgt acggtggatc cggtcagagc
      661 gccttgagca tgcgcgtgtt gccgagggtg ttcggcttca cgcgcgagag gtcgaggaac
      721 tcggcgatgc cctcgtcgtg cgagcggagc atctcgtagt agatctcctg cgcgatgatc
      781 gactccgcga cctcgtggta gccgtgacgc gagaagaagc cgacctcgaa ggtcaggcag
      841 aacaggcggc tgaggccgag ctcgcgggcg tcgtcctcga ggcgctcgag gagcgcgtgg
      901 ccgacgccgg tgccgcgcgt gtgcggggca gccgcgaggg tgcggatctc gccgaggtcc
      961 tcccacatca cgtgcagcgc gccgcagccg acgacctcgc cggacgcgtc gaccgcgacc
     1021 cggaactcct gcacgttctc gtagagcacc acgaggtcct tgccgaggag gatgccctcc
     1081 atcacgagcg gctcgacgag ctgctggatc cgcggcacgt ccccggtgcg cgcgcgtcgc
     1141 acgcggatgc cggctgcggg ctccacggac tcggcggtga ctggctctgc gctcacggtg
     1201 atgaccctct cgatccgcgg cacgggcgcc cggatcaggg gtccagccta gcgacgggcg
     1261 gatcccgcgt ccggggcggg cggctcggcg ccggcgcccg gcgcgggcga tgcgagccgc
     1321 gcgatcatcc gcggcgcgat ccacacgatc gccaccaccc ccaccaccgc gcgcagcccg
     1381 gcgaacacga gcacccacca gccgaccccg tcgcccgcga ccagcagtgc gaccccgatg
     1441 acgacgagcg ccgcgtccgc gacgaacggc acgcgcagcc agaacatgag gcggcggacg
     1501 ggatccatgt cagctgccgc cgaccggccc cggacgatcc gcgacgggtg cgcccgacgg
     1561 cggcgcccag cgatcggacg cggatcccgc gggcgcgccc gactcggagc gcgcatccac
     1621 cgcacgccgc gccaccggca gccgcacccc gaagaccgtg cgccccggct ccgactccac
     1681 ccacaccgcg ccgtggtgcg ccgacacgat ggcctgcgcg atcgcgaggc cgaggcccgt
     1741 gccgccggtc gagcgggcgc gggacccgtc gccgcgcacg aagcgctcga acaggttctc
     1801 ctgcatggcg ggcgggatgc cggggccgtc gtcggtcaca cggatgacgg catgggcatc
     1861 cgaccccgcg ccctccaccg cgagcgacgc gaccacgcgc gtgccggccg gggtgtgcgt
     1921 gcgggcgttc gcgagcaggt tgacgaccac ctggcggagc cgcgcgtcgt cgccggggac
     1981 gctcacggag tcgtccggca ggtcgaggtc ccagtcatga tccggacccg ccgcgctcgc
     2041 gtcgccgacc gtgtcgagga ggatgcgcgt gaggtcgacc ggatccgact ccagctcgcg
     2101 cccctcgtcg aggcgcgcga ggaggaggag gtcctcgacg atcgtggtca tgcgcaccga
     2161 ctccgactcg atgcgcgaca gcgagtgcgt cacgtcctcg ggcagctggt ggggaccccg
     2221 gcgggtgagc tcggcgtatc cgcggatgga ggcgagcggg gtgcgcagct cgtggctcgc
     2281 gtccgacacg aagcgccgca ccttcgcctc gctcgcctgc cgcgacgaca gcgccgcggc
     2341 gacgtgcccg agcaggccgt tgagcgcggc gcccacgcgg ccgacctcgg tgcgctcgtc
     2401 ggtgtcggat gcgggcacgc gggcctcgag cgcgacgtcg ccgcgatcca gctcgagcgc
     2461 ggccacgtgc gtggccgtgt cgacgacccg gtcgagcgga cgcagcgcgc gccgcacgat
     2521 gacggcgccc agcaccgcgg cgagcgccag ggtgagggcg gcgaccacgg agatcacgac
     2581 gatgagctgc tcgaccacgt cgtcggcggg cttcatcggc aggccggtga cgagggtcgc
     2641 gccggtggcc gcggtgtcac cgacgagccg atagcggccg agcgcgccgc cgaggtcgac
     2701 cgtgcggggg atcccgtcgg tgggcacgct ctgcagctgc tggctctgca cctgcgtcag
     2761 ctccaccgcg cccgcgccgc ccggctcgcc ctctgccgca tcgcggtcgg cgatgtagcc
     2821 gcccgagacc acgccgtcga cgatggtcgc gctgatcgtg ccgacctgct gcccgaacgc
     2881 gccgagcccg ccgggagggg cgccggggaa gctgccgtac tgatccgcgt cccggtcgat
     2941 gaggttcgag gagcgcgccg cggtggcctg cagctgctgg tcgacctcct gcacgagcga
     3001 cgcccgcagc gcgaggatgc tcaccgtgcc gatgaggatg ctcgcgagcg ccagcagccc
     3061 caccacgctg agcacgaggc ggcgccgcag ggtcatgccg cgcgcggcgg cggtgagccg
     3121 ggcccgcagc ggtgtggcgc gcagcggcgt cgtgcccggc ggcgtggcgg cctgcggctg
     3181 ggtcactccg cggccttgag catgtagccg ctgccgcgca ccgtgtggat catcgggttc
     3241 cgcccggcgt cgatcttgcg ccgcaggtag gagatgtaga tctcgaccac gctcgacttg
     3301 ccgccgaagt cgtagctcca cacccggtcg aggatctgca gcttgctcag cacgcggcgc
     3361 gggttgcgca tgaggtagcg cagcagctcg aactcggtgg cggtgagctc gatcgggtcg
     3421 ccggcgcggg cgacctcgtg gctgtcctcg tcgagcgtga ggtcgccgac gcggatcacc
     3481 ggatcgacgc tgtcgctcac cacaagggtc gagcggcgga tgaggccgcg cagccgggcg
     3541 acgacctcct ccaggctgaa cggcttcgtc acgtagtcgt cgccacccgc ggtgaggccg
     3601 gcgaggcggt cgtcgagcga gtccttcgcg gtgaggaaga gcacggggat gtcctcggcg
     3661 tcggcgcgca gccgcgacag cacctggagg ccgtcgaggt cgggcagcat gatgtcgagc
     3721 accacggcgt cgggcttgaa ctcgcgcgcg gcggcgagcg cctggtgccc gttctcggcc
     3781 gtgcggatct gccagccctc gtagcgcagc gccatctgga gcaggtcggt gagggacgcc
     3841 tcgtcgtcga cgacgagcac ccggatgggc gatccgtcgg cgcgcgtgag gcggggctgc
     3901 ggggcggcgg cgggctggaa gccggagggc ggggtggtgg tcacgggatc catcatgcgg
     3961 atgttcctat gaagcgacca tgaagcggcc atgggccggc ttcgacggac agcgcgaggg
     4021 tggacctcag aacgggaagg gatcgccgct ccgcacgccc tcgctgacga gcgccaccac
     4081 gacgaggccg agcaggatcg cgccgctgat ccacgggagc acgtcgacgt cgacaggagc
     4141 ggtgtccggt tcgcgcgtgc gccggaccag ctcctctgtc cgcatcgtgt aggcgcgcgc
     4201 gaggcagacg agcgccgtcg tcgcgagcgt ggcggtgccc gtccagcggg cgagcgccgt
     4261 gaccggctga ccgcacagcg cggccaccca cacgagcagg gcgcccaggg cgaagacgat
     4321 cccgatgacc caccacgcga ggtctgccgc gacatccgcc acctcgtagg cgaaggagga
     4381 cggggtgctc gcgtagcgcg ccgccttcct ctcgcgcttc gtcatgcgcg ccgggtcggc
     4441 gaagtcggcg cggtgccgct cgatcgcggg catcagcgcc tccacctcaa ccgatcgctc
     4501 gccgtcggcg ggcagcgcca ggaatcccgg gatctcgtgg tccgcgatcc ccgagtgcgc
     4561 gatcatgcgc gcgagccggt cgcgctcgac ctccgtcgtc cagccgggga cggcgatccc
     4621 ccaccgaccg gcctggtcgg gcgcgatgag ctcgcggtac atctccgcga gcgcgagtcg
     4681 ggcgtcgccg tcgcgggggt cctcgcgcag gtgatccttg aggagggcga gcgccgcggc
     4741 ccggtcatgc tcgtcccaga gcaggcgggc gcgggtcggg gcgtcgggat cgtcgggcac
     4801 cgggtgatgc tgccaggtcg gcgcgcgcag cgagcgggca gcgcaccggc agcgcatggg
     4861 cgtccgcgga cgacgacggg cccggcgcgt ggtgcgccgg gcccgtcgtg tcctgtcgtg
     4921 cggagggact agtgcttgtc ctccgtggcg cgcgtgacgg tctcgccctc gaccgtcttc
     4981 cggtcgccct tctgcttgtc gccgcgggtc ttcgcgaggc tcgcgacggt ggcgaccgtg
     5041 atggtcgcac cgatgaagag gagcgagaac cagatcggga tctcgggcgc ccacagcatc
     5101 ggctcgccgc cgttgatgaa gggcagctcg ttgacgtgca tcgcgtgcag cacgagcttc
     5161 gcgccgatga acgcgaggat cacggcgaga ccctgcgaca ggtagacgag gcgctcgagc
     5221 aggccgccga tgaggaagta cagctggcgc aggcccatca gcgcgaaggc gttcgcggtg
     5281 aagacgatgt acgcctcgtt cgtgaggccg tagatggcgg ggatcgagtc gagcgcgaac
     5341 accaggtcga cgaagccgat ggcgatgacg cagagcagca gcggggtgac gaagcgcttg
     5401 ccgtcgatct tcgtggtgaa gcggtcgccg acgaactcgt cgtggacggg gaggatccgg
     5461 cgggcaatgc gcacgaacat gttgtccgcc gcgttgccgc cgtggtcgcc cttcagctgc
     5521 tggtacgcga gcacgaacag cagcgcgccg aagatgtaga agacccacga gaagttctcg
     5581 atgagcgcgg cgcccagcgc gatgaagccg gcgcgcatga tcagcgcgat gacgatgccg
     5641 atcatcagca ccttctgctg gtacttccgc ggcacggcga acccggtcat gatcagcagg
     5701 aacacgaaca ggttgtcgat cgacagggcc ttctcggtga ggtagccggc gaagtactgg
     5761 ccgccgaagt cccagccgct ggtgaagccg atgccgacgc cgaagatcag cgcgaggccg
     5821 atgtagaagg ccgaccagcg ggcggactcg ccgatggtgg gctcgtgcgg cttgcgcacg
     5881 tgggtgaaga actcgtagac gaagaacgcg atggtgaccg cgatcgtgat gagccaggtg
     5941 gtcgtggtga tgttcacggg ggtctccggt gatgaggccg acgggaatcg gaacggctag
     6001 gtggcgcgcg gacgcatcca tgatcccacg cgggatctcc tcacaccggg gaaatgcctg
     6061 cgcctacgct ccgcggatcg tgcgtgccgc gggccgcctg cgcgcggagt cgcagggccg
     6121 cccggccgcc tgccggccgg gtcaagtcag gctcggcgcc tcgaacgggt aggcgacgta
     6181 ggcgaagcgg cgcgagtcgg gcgcccagct cgtgacgttg atggtgccct ggccgccggg
     6241 gaaggcggcg aggtcgcgcg tgcggtggct ctgccggtcg atgacgcgga ggatcacgtc
     6301 gtggtcggcg gggtgcccga gcgtgccggg cgggaagctc aggtagacga tgtgctcgcc
     6361 gtcgggcgac gggtgcggga accagttgac gcgctcgtcg gaggtgaact ggtgcgtgtc
     6421 ggtgccgtcg gtgcgcatcg tgaacagctg cgcgtggccc ggcaggtcgg atccccgctc
     6481 ggagttgaag tagagccagc cgccgtcggg cgagaactcg gcgccgtcgt ccgggaagcc
     6541 gtcgtcggtg agctgcgtgg tagggccacc gtcgacgggc acgaggtgga tgttcgtggt
     6601 ccactcgccg cgcgcgtcga gctggccgcc gatgacgctg agcatcgagc cgtcgggcga
     6661 gacgccgtgc aggtagttct tgaagccgag cgccggatcc cggtcggccg tgatccgccg
     6721 cccctggccg cccgcgccgt cgttccagag cacgtcgtag aggtggccgt cgcggccgga
     6781 gacgtacacg tgcgcgccgt cgggagacat gacgtggtcg ttgttgatcg gcgggacgcc
     6841 accgaggtcg accgcctgga agtcgacggc gggctcgggg agatccggat ccggctcctc
     6901 ggcgtcgggc gcgggcagcc gccacagccc gccctccgcg ttgacgacga gccagcggcc
     6961 gtcgggcgtc cagttcggcg cctcgatgtg cagcacggcc gactcggcga ccatgcgctc
     7021 ggcgcccgtc tccacgtcga cgacgaggag gcgggccagc tggccgtcgc gcagcgtcac
     7081 gcggtggatc cggcggtgcc ggtggatccg tcggcggacg tcgcggcggg cgcgtcgtcc
     7141 cggttgttcg cgaacgccga gtcgaagagg ctgtcgggcg tcggccagag gagggagcgc
     7201 acccgcgcga gggcgtcggg tgctccgtgc aggcggtcca tccccgcatc ctcccactcg
     7261 acggagacgg gaccgtcgta gccgatgctg cgcagggccc ggaaggcgcg ctcgaacggg
     7321 acgtcgccgt ggccgaccga gacgaagtcc cagccccggc gcgggttgcc ccacgggagg
     7381 tgggatccga gccggccacc gcgaccgtcg gacgtgacgc gcgtgtcctt ggcgtgcacg
     7441 tggtagatcc ggtcggcgaa gtcgaggagg aagcccaccg ggtcgatgcc ctgccacatc
     7501 atgtggctcg gatcccagtt gaggccgaag ccggggcggt gcccgatggc ctcgagcgtg
     7561 cggcgcgtgg tccagtagtc gtaggcgatc tcgctcgggt gcacctcgag cgcgtaccgc
     7621 acgccctcgt cgtcgaacac gtcgatgatc gggttccagc ggtcggcgaa gtcctggtag
     7681 ccggcgtcga tgaccgactc gggcacgggc gggaacatcg cgacgtacgg ccagatgcgg
     7741 gatccggtga agcccgtcac gcgcgtgacc ccgagggcgg cggccgcctt cgcggtgagc
     7801 ttcagctcct cggcggcgcg ctggcgcacg ccctccgcct ggccgtcgcc ccagaccttg
     7861 gagcggagga tcgcctggtg ccggaagtcg atcgggtcgt cgcacacggc ctggccggtg
     7921 aggtgctgtg agagcgcgtg cacctggagg ccgtggcgct cgaggatctc gaggcggccg
     7981 cggaggtacg ccggatcctc ggccgcgcgc cacacgtcga ggtgctcggc ggagcacgcg
     8041 atctcgaggg cgtcgaagcc ccagccgctc gcgagccggg cgacctcctc cagcggcagg
     8101 tcggcccact ggccggtgaa gagcgctacg ggggtggtga tctggggcat ggttccctct
     8161 cgtcgacggt gacggtgcgg tgcgtggcgt gcggtgcgtg cggtggcgcg gcccggtgac
     8221 ggcgcgcggg atccacgcta cacaccgggc cgcgcccgct cacgggtggc cgtcagcgga
     8281 agttcgccga ctgcgtgcgc tggtagcccg cgagggtgat gccgccgagc agcaccgtcc
     8341 acgccgcgag gaggatcagc gggatcccca tgaccgccgt gtcctgccgg gccgccgcgc
     8401 tcgtcagcgt gctccacgcg ccggtcggca gcagcaccgt gagcgactcc cagggcgtgc
     8461 cgctcgtgtc gccccccgtg aacaggccgc ccgcgaacga caggggcagg tacacgaggt
     8521 tggccaggcc gagcgcgccg cgggcgggga accagtagcc catcgcgagg ccgagcagcg
     8581 ccatcggcac ggcgccggcc aggacggcga gcgccacgga tccgagcgtc gccgcgtcca
     8641 cccggacgcc gcccgcgagg atcccgaccg cgaccaccgg gatcacgaac acgacgccga
     8701 agacgcacgc gaccgtgagc ttcgccgcca gccggatcca cgcgggcacc ggcgccgtga
     8761 acagccaccg ctcccacggc gactcccggg ccgatgcgac gccgacgccg aactggaacg
     8821 tcaccgtgcc gagcaccgag aacagcacgt agccgagcaa gacgctgagc cgcgcgctcg
     8881 gcgggccgcc ctgcggcaga ccgacgaccg cgtagatgag cacggggtag gcgaggagcg
     8941 gcagcacgaa ggccggcatg cgcgcgttct gcgcgagctc gctcacgacg tgggcgcggt
     9001 agacggcgaa ccggcgggct gcggtggggc ggaccggcat cggcgcggcg gtcatcgggc
     9061 gcaccccgcg tgatcctcgg tgcgcgacgg atcggcgggg atcgcgtccg cgccgcccgc
     9121 cagcacgcgc tccacgatct cgccgagccc gggctcgacg accgtgaggc ggggctgcgg
     9181 cacggcggcg agcaccagcc cggcgacgac gtcggagcgg tcggtgtcga tgacccaccg
     9241 gatccgctcg gggccgcgcg gctcctcccc cgcctcgggc accgcgccgg acgaccgcag
     9301 gcgccgcgcc tcggcgacgg tcgcgtcgaa gccgacccga cggacgccgg ccagaccgcg
     9361 gaagtcggcg gcggtccagt ggccgacgac gcgcccatgg tcgaggcaga cgaccgtgtc
     9421 ggcgagcgcc gcgacctcct ccatgtcgtg cgacgcgagg agcaccgtgc gcccggagtc
     9481 gcggaccgcg gcgatggcgt cgcgcacggc ggcccggccc gggatgtcga gcgccgcgga
     9541 gggctcgtcg agcaccacga cgggcgtccc cgcgccgacc acgcacgcga gcgcgacgcg
     9601 ccgccgctct ccgccgctga ggccgccggt ctggcgcgac gcgaggcggt cgaggtcgaa
     9661 gcggtcgatc gcggcggctg gggtgagcgc ggccgcatgc ggcacgaggg cgagcgccag
     9721 cacctcgcgc accgtgaggt actcggggaa ggcgagcgcc tgcggcatga ccgcgacgag
     9781 cgccgccgtg ggaccgccgc ggcgcacgtc gtggccgagc acgcgcgccc ggcccgcatc
     9841 cgggcgccgg gtggcggtga gcacgtcgat ggcggtggtc ttgccggatc cgttcggccc
     9901 gagcagcgcg tgcacgagcc ccggcgcgag ggagaaggac gcggcgtcga gcgcgcgcgt
     9961 ccggccgaag gcgcgggtga tcccctcgag ctcgatcgcg tcagtcatgg gatgcctcct
    10021 cctcggcgaa gcgccgcgcg cccggctccg cgccgccgaa cgagatcgcg tacagggacg
    10081 actgcgtcac cccgtcgagc ccgagcaccg cgtcgagctc gtggtcgacg aagcccaccc
    10141 agcccagcac cggcagcccc agcgcggtcg cgaccaggag cgcgttctgc cccacgtgcc
    10201 cggcctccag cagggtgagc cggtagcccc ggagcccgta cttgcagcgc gagcgctcga
    10261 agctgcccgt gatgacgacg gtgaccgccg ccgtctccgg gatcggcgcc atgagcgacg
    10321 gcgccgcgcg gcggaaccgc gcgagccgcc cgtcgcggtc gagcccggac acgtcgacga
    10381 gcgtctcctc gagcgggtcg agctggtgga tccccggctc gagccccacg accgaccgcg
    10441 cgaccacgtg caggtcgagc gggtacagcc cgccgcccga gggcacgaat cgcccgggcg
    10501 tgccgtcgcc gcgcggcccg taggcgaggc gcagcacggt ggcgagctcg gccagctcga
    10561 ccggccgccc gagcgtgcgc ggctcggccg accggcgcgc ggccagcgtc gcgcccagct
    10621 cgtgccggag cgggagcgcg cgcgggaggg gcagggccgg gagcagccgc ggcgcggagg
    10681 tggccccacc cggcccggcg tccgtgatgc cctgcgcctc ctgcgccatc tggtgcgcgt
    10741 accgcacgtc ggtccagccg gggtgggtga tccgcgtgat cttcgacgcc tcgtggaagt
    10801 cctccgcggg gtcgcccgca ggccggtcga cggcgccccc gacgctgaag atcggcccca
    10861 cgctcccgag ggagcgcccg gacgcgaggg tggcgggatc cgccctcgcg gacggacccg
    10921 tcgcggcctc cgcgcgctcg ggggtggcgt cggtctcgat ggtgctcatg ggatcctcct
    10981 ggtgcgacgg gcggtgggac ggcggcgggg acgggcggtg ccgcccgtca cgggaacggg
    11041 tgcgggacgt ggacgaggtc ggccggcccg tcgatcgcag gcccgtcgcg ccaccgccgg
    11101 tagaggcgcg ggtgcccgag gaaccgcgcg gcgtgcacca cgtcgagcgc cacgaggtcg
    11161 gggctcagcg cgcgcaccac gtggaagccg gccgcgcgca cctcgggcgc cgtgatgtcc
    11221 gcgagcagca cctcgatgcc ctcgcggtcg agcccggcga cgacctccgc ccagctgtcc
    11281 gggcccccga tggccgcgac ccgttcgtcc gagccgtcga gcgcggccgt gagcgggcgc
    11341 gcggacgggc ggcagtgcag ccggatgtgg tcctcgaact cgaccacgtc ctcggggtcg
    11401 atggtcggct ccgcgagcag ccgcaggcac cagttgtgcg tgtgcagcgc ctcgcggacc
    11461 gcgttgagga tcgcccggtc gagccggaag tcggccgcgc agcccaccgc gacgccgatg
    11521 cgatcgctgc gcatgaccgc gagcagcacg ggcacgtcgg ctgccgcgtc cagcacgcgc
    11581 accgtgaacg acgcgccgaa ccggccgcac agctcctcca ggcgctcgag ctcccggagc
    11641 gtcgcgtcgg tgagccggga gctgccgcgc cagtcgaagg ccgggggcgt ggatccgcgg
    11701 agccacgagc gctggaacgc gtcgcgctcg atgagctcca gcacggcgcg gcccgcggcg
    11761 aacccgaagt gcggccctgc cgcgacgccg gacgaggtgg ccggctccac gtgcggctcc
    11821 cggtgcccgt ccgcgcggtg cgggtcgtcg aacaccacca tctgcgcggg cacgtgcacc
    11881 gcgtcgcccc ggtgcagcga ccgcgccggc atccaggtga ggaggtcgcc cgcctgggcg
    11941 cgctcgtagt ggaaggccgg atcctcgcgc tgcgtcgggt ggaagcgctg gaaggcgtcc
    12001 ggccccacct ggcgggcgtc ggcgccgagg ggcgcgcgga acccgccggg cgctcccgcg
    12061 agcgacatgc gctccaccgc ctcgccgatg caggagcggc gcgcctccat ccgggatccg
    12121 cccggcccca tgctgaagcg ctcggactcc gtgccggtga ggaacccggt gtccgcggag
    12181 cggcccgagt agagggcgtc ggggatggcg tcgggcgtga aggccatggg atgcgcgtgc
    12241 tccacgagcc ccgtgtacgg gctgacgacg cccgccccgc cgcggctcat gcccgccacg
    12301 gcgaggccac gccggcgtag gggcgggggc cgcacgtgcc gcacctggcc acgcggaaca
    12361 cggcgtgcgc ctccgcctcc atgaccttgg gctcgatgac gagcacggtg ctggccacga
    12421 gccagtcgtg cgcgtggatc caccgggcgg cgaagcgcgc ggcgaacccg gccgtgatgg
    12481 cgtccaggct cgggtcgcgc ggcacgacgg cgaccgcgtc ggccgccgcg gcgtgatccg
    12541 cggcgaacgg cgtggtcgac gcccagcgca gcgcgacgca ctccaggcac ggcccctcgc
    12601 cgggcacgac caccggcccg acgagctgga agcggccgtc gaacgggtgc acggggagcc
    12661 acgggcgccc cgcggcgtgc atgcgcgcgc cgacctcgcg gaggaccggt cgcgagccga
    12721 ccgcgatgac caggtcggcg tcgtgctcgt cgccgagctc ggccgagggg agggcctccg
    12781 cgaggcccgt gagcagcgac gggatcatgt cgcccacgag cgcgatccgc gcgggcgacg
    12841 cggcgtcgcg cacgggaccg agcccggtgc ggtcgccgcc gttgcgccgc gcctcgtcga
    12901 ggacgtgcgc gagctcgtcc gggacggatc ccgcggagcc ggtcggcgac ccgaccacga
    12961 cgtcgcgcag cacgagctcg tcgaccaggt ccgccacggc gggggcgtgc gcggcgaagg
    13021 cccggtcgag gtccgcacgg gtgaagggac gggagaggag gcgcgacacc gcggagacgg
    13081 cgtcgcccga gggcagcttc agggagacca gctcgcgacc gccgaggagg tggagggtgt
    13141 cctccacctc cccgacggcg tagcggggac tcaccgagta cgtggtcgac gaatccatgc
    13201 gcgggcgatc agcgaggctg ctggtggccg ctgccgctcg acgagcacgt cgtgctgcag
    13261 cacagggtga cgtcgcccat cacgagctcc tcctccgcgc cgcggtgcgt gatggtgaag
    13321 ccgaaggcct ccgccagcag cgcgtcggac gccgcctcgc ctccggccgc gggcgcgacc
    13381 tcgggtgcgg tggtgcgcgt cggttccatg agcagtgaca ttgccgttcc ttcctttggg
    13441 tgggtgggac gacgcctttc tagcacgatc ttccgtgccc tggtcctatg cgcatcacct
    13501 gttgacaacc catccgcgag gcggcacgat ccgcccgcgt cgaggcggcc cgggtcgtat
    13561 ccgacgcgta ccctggagcc cgtgacggac gagatgctgg ccttcccctg ggaggacgac
    13621 ctcgcccccg cagcacccgc gccgcctcct cccccaccgc acctgacgcg catcgtcgcc
    13681 cactcgtcgg atcgcgtcgc ctggctccgc gcccgcagct tcggcatcac cgcgaccgac
    13741 gtcgcacgcc tcgcgaccga cgcgtcgctg caggccgtcg cgctcgagaa gctctacgga
    13801 tccggcttcg gcggcaaccg ctacaccgac cacggccggg agcgcgagcc cgagatcgcc
    13861 cgctgggtcg aggcggagca cggcatcatc ccgagcgcgc acctgttcca cgcggagggc
    13921 cagcgccgcc acctggcgac ccccgacggc gtgggcctcc gggcagacgg ccggctcgag
    13981 ctcgcggaga tcaagacgac cgcgaagccg tggcgcagca tcccgcgcaa ctacctgcgc
    14041 cagatctggt ggcagcagta cgtgctcggc gccgagcgct cgctcatcgt ctgggagcag
    14101 cacgtggact tcgtgcccgt gcacgacatc ccgaagtgga agtggatcga ccgcgacgag
    14161 gcggagatag ccgcgctcgt ggcgcgcgcg aacgacctca tcgcgctcat cgtgcggatg
    14221 gcgaacgcgc cggcgggagc ccgcggcctg gcctgagcgg cgctgcctgc gaggcccggc
    14281 ccggcccggt tcgcgcgccg tcgccgccgc cgtcgccgtc ggcgagtgcc ctccgcattc
    14341 ttctcgcccg gggaacaccg cggaaacacg cccgactcac tcggcggctt cactggacga
    14401 gcgggggccg gtgggatcca ccttgccgcc gcgttccgag gaggggtcgc acgatgagcc
    14461 aggtcatcca gtcgagagcc ggcgtcgccg ccgcggccga gcgggatcgg gcggcggccg
    14521 ccgtcgccct ggcgccccac ggggagacca tgcgcgcggt cgtcgtcacg gagaccggag
    14581 ggcccgacgt gctgcacgtc gcggacgtgc cggtgccgca ccgcctcgac tccgaggtgc
    14641 tcgtgaaggt cgtcgccgcg ggcgtgaacc ccatcgacct gcgtctccgc gcgggcgagc
    14701 ccggcggccc gacactcggc gtcctgcccg cggtgctcgg ccgcgacttc agcggcgtcg
    14761 tggtcgagtc gccctacgag gaccacgcgc tgcatcccgg cgacgaggtg ttcggcctcg
    14821 ccatggtgcc gcggatgccc ggcagctacg ccccctacat cgccgtcccc agcgtgagcc
    14881 tcgcccggaa gcccgcccgg ctctcgcacg tggaggccgc ggcgacgccg gtcagcgccc
    14941 tcaccgcctg gggcatggtc gtcgacatcg gcaaggcgca cgagggccag gtcgtcctgg
    15001 tgcacgcggg cgcgggcggc gtcggccact tcgcggtcca gttcgcgcgc cacttcggcg
    15061 cgcgcgtggt cgcgacgggc tcgccccgca acgtcgactg gctggcggag ctcggcgccg
    15121 acgaggtcat cgaccgctcg caggtgcgct tcgaggacgt gctcgccgac gtggacgtgg
    15181 tgatcgacct ggtcggcaac tgcaccgacg acaccggcac ccgctcgctg caggtcctcc
    15241 gtcgtggcgg cctcctggtc agcgcgcccg tccgcggctg gccgacgctc gtgcaggacg
    15301 cggccgcggt cggcgtgcgc gccacccact acgaggtcgc gcccgacggg cagaagctcg
    15361 cggtgatctc gcgcctgctg gagtccggcg acatcaaggt ctacgtcgac gaggtcttcg
    15421 acctggagga cgccgccgag gcgcaccgcc acatggagag cgggcacgct cgcggcaagg
    15481 tcgtcctcaa cgtggcgcgg ggctgacccc cgccgacagg cgaggtcgcc ctcgacgtgg
    15541 cgcggggctg accctcgccg gtcgcgcccg ccgcgcccgc tcagcgcggc agcgcctccc
    15601 gtagcgcgtc gacgatccgg gtcccgcggt cgtcgtcggc ctccatccgg ttggtgagga
    15661 acgcgaagcc gacccggtgc tcgacgtcgg cgaaggcgac ctggccgcca gcgccgtcgt
    15721 ggccgaggct gccggatccg aggtagcggc gcgcggccga gtcgagctgg aagcccatgc
    15781 cccaccgtgg ccacgggccc ggcacgtcga acgcgggcgg ctcgtcgccg ccggagacgg
    15841 gacgggtcgc gaggcggatc gtgtcgtcgt cgagcaggcg cacgcccgcg gtctccacga
    15901 ccacggccga ccagacggcg gcgagcgcgt gggccgtgcc gatgccgccg gcgccgggga
    15961 tctccgccgc ctgcacgtcc gcgcgggaga agcccgcgtc gtcgcccacg agctccagcg
    16021 gcagcgcgcc gccgagcgtg agcgcgcgca gcggcaggtc ggggccgccc gccgcgacat
    16081 ccgcgcgctg ccgggaggtg agctcccgca gcgtcgtgcc cacgcgcatg cgcgcgacgc
    16141 gctcgccgac ctcgggcggg atcccgatcc aggcgtccac ccccagcggc ccggtcgcga
    16201 gcgcctggaa ccacgcgccc ggcatgagcc cggtgaccct ccgcacgatc tcgcccgtca
    16261 gccaaccgtg cgtgatggcg tggtaggccc acgccgtgcc gggctccccg cgcggctcct
    16321 ccgccgcgac gagcgcggtc gcgcgatccc agtcgacgag gtcggacagc gtccagtcca
    16381 cgcgcggcgc cgcgatcccg gcacggtgcg cgagcgcgtc cgcgacccgg gtccccgcct
    16441 tgccggcgcg cgcgtactcc ggccacagct cggcgaccgg ctggtcgtag cgcagccgcc
    16501 cgtcctggac gaggcgcgcg accaggatcg acatgacccc cttggtcgcg gagaacagca
    16561 cgctcggggt gtcgagcccc cacgcgcggc cggtcacgtc gtcggcgacg ccgcccgcga
    16621 ggtccaccac cacgtcgccg cgctgccgga cggagagcgc ggcgcccgtg ccgacgtcgg
    16681 acgcgacggc gtccgcgaac gcgcgccgca cgccctcgaa gccgggcgcg acccagccga
    16741 ccacgccgtc ggcgcgcgtc ccggcgccga cggccgcccc cgcgccggtc acgacgcgga
    16801 cccggcgggc accgcgacca gcagcccggc cgcgtcccat cgcacgggca ccggatccgg
    16861 gatgcggccg acgaacgagc cgtccgcgcc ggcgtcctcg aagccgagga gcgccggacc
    16921 cgacggcgtc cggacgatgc gcgcggcata cagcccctcg ccgtgcagga gccgggcgcg
    16981 cccgatgtcg acggggcggc cgaacggctg gtcgtcgtcg agcggcagcg cgaagacgcc
    17041 gccctcctgc ccggctcgcg cgcccgcgag gtcggacccc gcgcacgaga acacgagcac
    17101 ccgccggccg tcgacctccg cgacctgcag cacctcgagg tgcgcgaacc ctgcgccggg
    17161 cgcgctgagc ggcgccgcgg cggtccaggt cacgaggtcg cgcgagacgg cgtgccccac
    17221 gacgccgcgg tcgagcggat ccgcgtccgg acccggcgcg gcggcctgcg accgcgcggt
    17281 gacgagcatg cgccagccgt cgcccgcggg gtccggctcg acccagggat cccgccacgc
    17341 ctcctcgcgc cacgtgccgt cggcgagcgt ctcgtaccag cgcgggtcgg ccgacagcgc
    17401 ggacacgctc gccttcaccc accggtgcag gtcggccgaa gtcgcctgca gaacggtctc
    17461 cacgttcgcg cccgcgtcgt cccgcgggaa caccgagccc gtgtacgaca tccgccagag
    17521 ccccgacggg tcgcgcgtca cgctgcccgt ccacgtcgcc gacgcgtccg gcgacccggc
    17581 cggcccgtgc tcgaggacga cgccgtggtc ggtccacgtg acgaggtcgg tcgaggtcgc
    17641 gtggcccacg gcggcgttcc ggtgtcgcag gtccggatcc ccgagcgcgg tcggcgcgtg
    17701 caggtagaag aggtgcgtcg tgtcgccgtc gaccgcggtc cacgagtccc agacccagtg
    17761 cccgggcagc gcgaacgcca tcagcccttc accgcgccct gcagcagcgc cgcgatgaac
    17821 tgccgctgga agatcacgta cacgatcacc gttggcagca tcacgatgag cgacgccgcg
    17881 aacagcagcg gcagcgcatc gatgtactgg ccctggaacg cgccgagcgc cccggccatg
    17941 gtgcgctcgc tcgggtcgtc gatcatcacg agcggcagca ggaactggtt ccaggtccag
    18001 aggaacagga ggatcccgag cgccgagagc gccggccgcg cgagcggcag ctggatgctc
    18061 cggaactcct gccagatgct cgcgccgtcc acgcgcgcgg cctccgacag ctcccgcggc
    18121 acgccgacga agtgcgcgcg catccagaac acgctgaacg gcatgtacag cccgatgagc
    18181 gggaggatga ccgcccacct ggtgttgatg aggccgaagc ccgtcatctg gtagtagagc
    18241 gggatgatga tcgcctcgaa cgggatggtc agcccgatga tcatggcgac gagcacgtac
    18301 ttcccgccgg gcacccggag gttcccgagc gagtagcccg cgagcgtcgc gcagacgagg
    18361 ctgacgggca cgaccatcac cacgatgaac aggctcgaga gcatcagcgt gccgatgttc
    18421 ccgaccgtga acgccgtcac gaagttctcc cagtaggcgg gcgtcggcca ggagaagccg
    18481 ttgggcagcg agtcgggcga ctgcagcgcg gcggtgagca tgctggcgaa gggcagcagg
    18541 gtgagcacga ggaccgcgat cagcaggatg cggcccacga cgagctcggt gcggttgacg
    18601 atcatcggtc gcgctccctc gagagtcgtt ggacggggag cacgagcagc agcacgaaca
    18661 cgagcagcac cacgccgaac gcggacgcga ggcccacctg gctctgcacg aacgcgagcc
    18721 ggaagatctc gatgccgggc acgagcgtcg tggtgcccgg cccgcccttg gtggtcgtgt
    18781 agatgatgtc gaacgtgctc agggcggcga tgaccgtgat ggtcacgagc accgcgatct
    18841 cctgccggag gcccggcagg gtgatggtga cgaactcgcg gaagaagccg gcaccgtcga
    18901 gccgcacggc ctcgtagagc gagccgtcga tcttgcccat gcccgtgagc agcagcacgg
    18961 tgcagaggcc cgtgagcacc caggatccga tgagcccgac cgcgggcagc gccgtgccga
    19021 agtcggcgag ccaggagcgg gacaggaagc cgagccccac cgcgtcgagg atggagttga
    19081 tggtgccgga ctgcgcgtac atccacgacc acgcgatgcc cgccgcgacg agcgggacga
    19141 tctgcggcag gaacaggatg gtgcgcgaga tcgacgcgaa cgggccctgc ttcatcccgc
    19201 gcaggagcgt ggcgagggcg aggcccgcgg tgatggggat caccatgaag aagatcacga
    19261 ggatcagcgc gttgacgatg ggcgtcagca gcctggtgtc cgtgaagatc tgcacgtagt
    19321 tgtcgaggcc gatgaaggtc gaggcgccga tcccgttcca cttgtagaac gagtactgca
    19381 ccgccgtgat gagcggccag acgacgaacg cagcgtaggc cgcgacggcc ggcagcagca
    19441 tgatccagcc gaccgtcgcg gtgcgacggg cctcggggcc gagccggcgg cgccgcgtgg
    19501 gcgcgcgccc gggcccgccg ccgcgcgtgg acggccccgc ggggacggcg gcggtcgccg
    19561 tcgcccccgc ggggatggtg cgatccgtgg tgctcactgt gcggcgaggt cctgctcgta
    19621 gaagtcctgc gtggccttca ggaagtccgc gggcgtcatc ttgtcggtga gcagcagctg
    19681 ctcgttcggc tggagcgagc cctggtagat gccggccgtg ctgttcgcca tgaagtcgac
    19741 gaagccgtcg tcgtcgccga cctcggcgga cagctcgagg gccttcgcga tgaggctgcc
    19801 ctcctgggcg gtcggcaggg cctgggccgg gtcgccgccg ggcgacgcgc ccgtcacgtc
    19861 gacgacgatc tggcgcgcct tctcgtcggt cacgatccag ttcaggaacg cggcgacgac
    19921 gtcggcgttc ttcgacttgg ccgggatggc gaaggtgttg cccgtgccca tcgcgacgtg
    19981 cttcccgccc gcctcgaccg gcggcacgag gccgaactgc gcgccgccct ggccgagggc
    20041 cttctccacg ttcgcggcgt cccagttgcc gtcccacatg aacagcccct ggccggccga
    20101 gaagttcgac accatcgtcg tgtagttgat ggcgttgacg tccggcggga ggtacccggc
    20161 cttcgcccag tcctggaact tcgtggcgcc tgcgagcgcc gcgtcggtct ggatggtcgc
    20221 gcccggcttg ttgtacatcc agtcgacgag gtcctgcttg tcgccctgct ggttgatgag
    20281 cgactggagg atgaaggtcc cgacgccgtc ctgcatgccg gtctggatgg ggagcacgcc
    20341 ggcgtccttc gccttcgcga ggtccgcctc gagctcgtcc atggtggccg gcatctcggt
    20401 gatgcccacc tggtcggcca gctcctggtt catgtagatg cccgtgacgc tgtagccgat
    20461 gccgaactgc cacagcgagc cctcgccgcg cacgccctgg tcgtccatcc gggcacccgc
    20521 gagctggccc gccgggaagc ggtcccagcc gtaggcgtcg aagtacgggt cgaggttcgt
    20581 gaggagcccg tccttgaccg tggtgccgag cgtcgagagg cggatcaggt ccggggcgtc
    20641 gtcgctcgcg aggaggcgcg gcgtgttcgc gaggaggttc tggaagctat cgcgcgtgat
    20701 gtcgaacttc acgttcgggt gctgcttcgt gaactcggcc gtcagctcgt ccgtgaccgg
    20761 gaagccggtc tcgtcctgga tccggatcgt gaggtcgtcc gtcgggatcg cggtgctcac
    20821 atcgccggcg ggcgcggagg cgacgggcgc gctgccgggg gcgcagctcg cgagggcgag
    20881 cgccgagatc gcggcggcgg cggtcagcgc tgccgcgcgt cccgcccttc tcatggtgga
    20941 catgcggtga ctccttcgtc aggtgatgcg ggggcggggc gggtcgtgcg ggagccgcgg
    21001 gcaacggcgc acgcggtgtg acaggctggt ggtaaatcca tttacctgtt gcaggagatc
    21061 atgcgcgcag ggacgccggg tgtcaacccg gcatctccgc ggtcgacgga tcaccggata
    21121 cgctcacgag gaggaggacg tcacatgcgc cagaagcgac cgaccctggc ggacgtggcc
    21181 cggctcgccg gcctctcccc gacggcggcg tcgcagatcc tcaacggcac gccagagacg
    21241 cgcttctccg aggactccca ccgccgcgtc ctagccgccg ccgccgagct cggctaccgg
    21301 cccaacatgg gcgcccgggc cctccgcacc gaccgatcgc tcaccatcgg cttcatctcc
    21361 gacgtcgtcg ccaccacccg cttcgcgagc ggcctcatcc gcggcgcgct cgtcgaggcg
    21421 gagcgcgccg ggcacgtcgt gctcgtgctc gagaccggtg gcgaagaggc gcgcgaggcc
    21481 gaggccgtgt ccgcggtgct cgaccgccag gtcgacggca tcgtcttcgc cacgatgcgc
    21541 gcacgggagc tcgtcgtccc cgacgtgccc gcctcgacgc acgtcgtgat gctcaacgcc
    21601 accagccccc accacggcag ctccgtgctg ccggacgagg aggagggcgg acgccgcgcg
    21661 gtcgacctcc tcgccgccgc cggccactcc gatgggatcg cgctcctcgg cagcgacatc
    21721 gcgaccgagc ggagcctctt ccgctcggag acggtggcgc gtcgcctgca cgggatccgc
    21781 gcggagatgg ccgagctcgg cctgcgcttc gcggccgagc ggtcgtgcgg ggactgggag
    21841 ccggacgccg gctacgaggc cgcgggcgcg atcctggacg cggcgcccgg gacccgcgcg
    21901 atcctctgcc tgaacgaccg cctggcattc ggggcgtacc aggcgtgcca ggagcgcggg
    21961 atccgcgtcg gcatcgacgt ctcgctcgtc ggcttcgaca acgacgagct ggcgtcctac
    22021 ctgcggcccg gcctcacgac catcgccctc cctcaccagg agatgggacg agaggccgtt
    22081 cgtctcgtcc tgcgcgacgc cgagccgggc gagcgcctcg tggggatgcc catggtcgag
    22141 cgcggctcga tcgccccggt cacgccggcg gacagcggca cggcccgggt cgctgccgcg
    22201 cgcatggcgg ccctggcggc gtcggcctga cagagggcac cgcggccgcg ccggcctact
    22261 ctcccgcggc cgccgccagc gcccgctcca
//
