LOCUS       NZ_CP095274            23162 bp    DNA     circular CON 08-MAY-2024
DEFINITION  Clavibacter michiganensis subsp. michiganensis strain N.P.
            chromosome, complete genome.
ACCESSION   NZ_CP095274
VERSION     NZ_CP095274.1
KEYWORDS    RefSeq.
SOURCE      Clavibacter michiganensis subsp. michiganensis
  ORGANISM  Clavibacter michiganensis subsp. michiganensis
            Bacteria; Actinomycetota; Actinomycetes; Micrococcales;
            Microbacteriaceae; Clavibacter.
REFERENCE   1  (bases 1 to 3334132)
  AUTHORS   Akhremchuk,A.E., Miamin,V.E. and Valentovich,L.N.
  TITLE     Genomic analysis of Clavibacter michiganensis subsp. michiganensis
            strain N.P
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 3334132)
  AUTHORS   Valentovich,L.N., Akhremchuk,A.E. and Miamin,V.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (07-APR-2022) Center of analytical and genetic engineering
            research, Institute of Microbiology, National Academy of Sciences of
            Belarus, Kuprevich 2, Minsk 220141, Belarus
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: 07-APR-2022
            Assembly Method :: Barapost v. 2021-06-28 edition; Flye v.
            2.9-b1768; canu v. 2.2; SPAdes v. 3.15.2
            Assembly Name                     :: Cm-NP_v1
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 140.0x
            Sequencing Technology :: Illumina MiSeq; Oxford Nanopore MinION
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_022983255.1-RS_2024_05_07
            Annotation Date                   :: 05/07/2024 05:27:08
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,225
            CDSs (total)                      :: 3,170
            Genes (coding)                    :: 3,147
            CDSs (with protein)               :: 3,147
            Genes (RNA)                       :: 55
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 2, 2 (5S, 16S, 23S)
            tRNAs                             :: 45
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 23
            CDSs (without protein)            :: 23
            Pseudo Genes (ambiguous residues) :: 0 of 23
            Pseudo Genes (frameshifted)       :: 5 of 23
            Pseudo Genes (incomplete)         :: 18 of 23
            Pseudo Genes (internal stop)      :: 6 of 23
            Pseudo Genes (multiple problems)  :: 4 of 23
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 06:43:17
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 2226572
            Orig. end                         :: 2249734
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP095274.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            Bacteria and source DNA available from Dr. Vladislav E. Miamin,
            Faculty of Biology, Belarusian State University (Minsk, Kurchatova
            str., 10).
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..23162
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="lanthipeptide-class-ii"
                     /region_number="8"
                     /rules="cds(LANC_like and DUF4135)"
                     /tool="antismash"
     cand_cluster    1..23162
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="cds(LANC_like and DUF4135)"
                     /kind="single"
                     /product="lanthipeptide-class-ii"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..23162
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:13162](+)"
                     /cutoff="20000"
                     /detection_rule="cds(LANC_like and DUF4135)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-ii"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..13162
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="cds(LANC_like and DUF4135)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-ii"
                     /protocluster_number="1"
     gene            complement(765..1613)
                     /locus_tag="MU580_RS10415"
                     /old_locus_tag="MU580_10415"
     CDS             complement(765..1613)
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /function="ABC-type dipeptide/oligopeptide/nickel transport
                     systems permease components"
                     /gene_functions="transport (smcogs) SMCOG1085:
                     binding-protein-dependent transport systems"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012038645.1"
                     /locus_tag="MU580_RS10415"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MU580_10415"
                     /product="ABC transporter permease"
                     /protein_id="WP_012038645.1"
                     /transl_table=11
                     /translation="MSATLATIDAPRARPRSRARLAGGLVIPVLVVLVMLLWALVPGLF
                     ASGSPTASVAPSLQAPSAAHWFGTDSTGRDLYTRVVFGASQSVVGAVVAVLVGLVVGTL
                     LGVVAGTVGGIVDDVLMRLVDVLLAIPGLLLSLSIVILLGFGTTNAAIAVGVTSIAVFA
                     RLSRAEVVRVRISEYVEAAYGSGGTLVQVLRRHVLPNSLTPVIALAALQFGSAILQIST
                     LGFLGYGAPPPTPEWGLLVAEGRDYVATAWWLTVLPGAVVVAVVLATNRISQSIRGGQL
                     A"
     gene            complement(1610..2545)
                     /locus_tag="MU580_RS10420"
                     /old_locus_tag="MU580_10420"
     CDS             complement(1610..2545)
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1118:
                     binding-protein-dependent transport systems"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012038646.1"
                     /locus_tag="MU580_RS10420"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MU580_10420"
                     /product="ABC transporter permease"
                     /protein_id="WP_246929393.1"
                     /transl_table=11
                     /translation="MSYAIRRAGQAVIVLVLAYVVAYVLLAALPGDAVLARYGSPELGL
                     APEQLAAIRESYGADRPLIVRLGESAAAFAQGQLGYSVQSGAAVSTLLATAIPSTLVLA
                     VLGLLVAVVLAVPIAFLATYGCARWIRRVFRDLPPLLVSLPVFWVGIILIQVLSFRLGL
                     VPIIGASPGEALILPVLTIAVPIAAPLAQVLIRSIDDVSAMPFVEVVRARGAGTPWLLL
                     HGVGRNALLPTLTMAGLLFGELVGGAVVTEAVFGRAGVGQLTVQAVASRDSPVLLAVVV
                     LSTVAYVVINLAVDLLYPVLDARLRRGGAR"
     gene            complement(2586..4238)
                     /locus_tag="MU580_RS10425"
                     /old_locus_tag="MU580_10425"
     CDS             complement(2586..4238)
                     /GO_component="GO:0043190 - ATP-binding cassette (ABC)
                     transporter complex [Evidence IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1068:
                     extracellular solute-binding protein family 5"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012038647.1"
                     /locus_tag="MU580_RS10425"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MU580_10425"
                     /product="TIGR04028 family ABC transporter
                     substrate-binding protein"
                     /protein_id="WP_246929395.1"
                     /transl_table=11
                     /translation="MPRPPRPVIALTALVAATGLMAGCSAGGGGDQAASGEPKAGGTLT
                     YLEPQTWTTLYPPAAGFYPNGAVVNNITDRLLWQDPETLELEPWIATALPEVNADATEY
                     TFDIRTDVTYSDGTPLTAQNVVANFDLYGKGDVDRALTVSEAINNYDRGEVVDADTVRF
                     HFTAPAPGFAQATSTINSGLVSDSTLAKADDGFGPGQAETVIGSGPFTVSGESVGTQIQ
                     LAAREDYDWAPPEAAHQGRPLVDGVDLIVAAEDSVRVGTVVAGQADVARQIEAPDEAQF
                     RTGDLQLVAAATNGVDNGINLRFRTPQLEDVRVRQAIIAGVDRQAILDTLFSDSYPLAT
                     GVLAKSALGYVDTSSYYAHDADKAAALLDEAGWVPGSDGIRQKDGRKLELVVNEALPQP
                     RSKEVVTLIQSQLAEIGVEVELFSGDQAAQTKASQDPDALEAYHSMVGRSDYDVLKSQY
                     SSTNRNVLLNRNPADGSIADPELDALLTRIASEPTTEGRQAASEAAQQRIADQAYVLPL
                     FEEPQVYGLRGDVRGFATESVGRPVFAGVWLDR"
     gene            4452..4943
                     /locus_tag="MU580_RS10430"
                     /old_locus_tag="MU580_10430"
     CDS             4452..4943
                     /GO_function="GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012038648.1"
                     /locus_tag="MU580_RS10430"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MU580_10430"
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="WP_246929396.1"
                     /transl_table=11
                     /translation="MTTPPPVRPAVPDDADGIAEVHIRTWQETYAHLLPAAYLDGLDVA
                     ARAEQWRGSLGDPSGAPTFVALDGDRIVGFTLAGPARDEDPPRPFQLYAIDVVASAHGT
                     GAGQALFDAAVGDSPAYLWAADDNPRAAAFYRRNGFVRDGGVERQTYQGAEMVTVRMVR
                     "
     gene            complement(4980..5726)
                     /locus_tag="MU580_RS10435"
                     /old_locus_tag="MU580_10435"
     CDS             complement(4980..5726)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015780271.1"
                     /locus_tag="MU580_RS10435"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MU580_10435"
                     /product="ABC transporter permease"
                     /protein_id="WP_094114558.1"
                     /transl_table=11
                     /translation="MFRAEAVKLKRSSIWIIAVLLPLLAVVTGTINLANNTQTLDSGWA
                     SFTSQVVLFYGLLFYSMGISLLAAAIWRVEHRGTNWNALLTATARPIRLVLAKIVAILV
                     PVALMQAVLVGGTAVSGLFVLRLDGPFPVAFLLVGLIATVAALPLIAVQSLLSLLLRSF
                     AAPVALCLVGCVAGVAAVTSAALRPLAEVLPQAINTRALNLGSTAIAGSGGLTAADTLP
                     LLATSVGLAALVVLLTLAAIRVVKLR"
     gene            complement(5732..6472)
                     /locus_tag="MU580_RS10440"
                     /old_locus_tag="MU580_10440"
     CDS             complement(5732..6472)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005885337.1"
                     /locus_tag="MU580_RS10440"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MU580_10440"
                     /product="ABC transporter permease"
                     /protein_id="WP_231840595.1"
                     /transl_table=11
                     /translation="MAIEFRKMHRLRSLPLLIGMVVAVAALSSASQFAGSTRAGFDDPG
                     AHPWAALLLGYTLMAAMTSPILTAVIASRQTDIEHQAGGWILAAGAGRTAGELCRAKLV
                     ALAVLLVPAVLIQSLLVIAAGYAAGIRVPVEVGPWALYTLLLYLVDVAFCALHVWLAAR
                     VENQLISVGVGMLGAFLAVFSLLLPSVASRAIPWGYYAVISQAGQSDAGVGYVASPLGW
                     IAGFLVVVAAAFALATIRLDRVER"
     gene            complement(6481..7380)
                     /locus_tag="MU580_RS10445"
                     /old_locus_tag="MU580_10445"
     CDS             complement(6481..7380)
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /function="ABC-type multidrug transport system ATPase
                     component"
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015780269.1"
                     /locus_tag="MU580_RS10445"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MU580_10445"
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_012038651.1"
                     /transl_table=11
                     /translation="MSAVIATRGLTKRFRDHVAVDALDIEVPQGSVYGFLGPNGSGKST
                     TMKMLLGLTQPTSGEIHLFGQRLTPATRGGLLPSIGSMIEAPAGYGHLTGWENMRIVRD
                     MLGLAEAQVERAFATVRLTQHRDKLVRRYSLGMKQRLGIAMALARDPSLLVLDEPTNGL
                     DPAGIEEVRSLLMDLAGQGITVMVSSHLLDEIEKMAGVLGILADGRMIFQGTRAELFEH
                     SIPDLVIETSAPDRAMAEVAGAARSPEGIRLSARSKDETADIVRRLVAADVPVHEVRRL
                     PQSLEDVFMDITGRGGQL"
     gene            complement(7534..8208)
                     /locus_tag="MU580_RS10450"
                     /old_locus_tag="MU580_10450"
     CDS             complement(7534..8208)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /function="Response regulator containing a CheY-like
                     receiver domain and an HTH DNA-binding domain"
                     /gene_functions="regulatory (smcogs) SMCOG1016: LuxR family
                     DNA-binding response regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011775166.1"
                     /locus_tag="MU580_RS10450"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MU580_10450"
                     /product="response regulator transcription factor"
                     /protein_id="WP_012038652.1"
                     /transl_table=11
                     /translation="MTDAPAPIRVVVVDDQSLVRDGFARIVDAQPDMAAVGVCADGEQA
                     VARVVELRPDVVLMDVRMPVLDGIEATRRLVEGGRAEGTRILGLTTHDTDSYAIRMLRA
                     GAVGFLLKDSTAVQLVDAIRSVHNGTFAASMSTTQRLLERLAVERTAPPDPDTAALDVL
                     TDRERVVFTRLVTGASNPEIARDLSIAEVTVKTHVGHILTKLAVRDRVHLVIWAHRRGL
                     AA"
     gene            complement(8205..9341)
                     /locus_tag="MU580_RS10455"
                     /old_locus_tag="MU580_10455"
     CDS             complement(8205..9341)
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0000155 - phosphorelay sensor kinase
                     activity [Evidence IEA]"
                     /GO_function="GO:0046983 - protein dimerization activity
                     [Evidence IEA]"
                     /GO_process="GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /codon_start=1
                     /function="Signal transduction histidine kinase"
                     /gene_functions="regulatory (smcogs) SMCOG1048: sensor
                     histidine kinase"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: protein motif:HMM:NF019350.4"
                     /locus_tag="MU580_RS10455"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MU580_10455"
                     /product="histidine kinase"
                     /protein_id="WP_012038653.1"
                     /transl_table=11
                     /translation="MRRGSLRAQGDQVVAGAAVVLCAIMGVLGQPDWIWSSLMALTLAV
                     RHARPVTAALLATAISSAHMLATSSLLFPGDVVLLVAAYSVAAHAADRLRHVGLALGAC
                     FVVVLAARTLTGGELGSTGSVGMVIALVSVSFAVAWAAGLLERRRSEAVRTAELRTTLS
                     ERDADARTRLAAYEERERISDDMHDVLAHTLTSVIVQAESGRATAPSPEASRMFRTISE
                     TSRAALHEVRGLLAPTDADADVRPIPGWDDVDALVEGFRGSGLGIDRQDAGSPRPLLPG
                     VGFAVYRVVQESLTNAMRHGAGGTARLRVEWSPDALAITVANAVVRDKRGCPVQEHRGL
                     AAIRRRCALYGGQARYACDDEFVLQARWPTAPLGGSTP"
     gene            9703..9909
                     /gene="micA"
                     /locus_tag="MU580_RS10460"
                     /old_locus_tag="MU580_10460"
     CDS             9703..9909
                     /codon_start=1
                     /function="Lantibiotic precursor"
                     /gene="micA"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012038654.1"
                     /locus_tag="MU580_RS10460"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MU580_10460"
                     /product="lantibiotic michiganin-A"
                     /protein_id="WP_012038654.1"
                     /transl_table=11
                     /translation="MNDILETETPVMVSPRWDMLLDAGEDTSPSVQTQIDAEFRRVVSP
                     YMSSSGWLCTLTIECGTIICACR"
     CDS_motif       9703..9843
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence:
                     MNDILETETPVMVSPRWDMLLDAGEDTSPSVQTQIDAEFRRVVSPYM"
                     /locus_tag="MU580_RS10460_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       9844..9909
                     /prepeptide="core"
                     /locus_tag="MU580_RS10460_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class II"
                     /score="-3.60"
                     /molecular_weight="2109.5"
                     /monoisotopic_mass="2108.0"
                     /core_sequence="SSSGWLCTLTIECGTIICACR"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MNDILETETPVMVSPRWDMLLDAGEDTSPSVQTQIDAEFRR
                     VVSPYM"
                     /leader_location="[9702:9843](+)"
                     /alternative_weights="2127.5"
                     /alternative_weights="2145.5"
     gene            10001..13162
                     /locus_tag="MU580_RS10465"
                     /old_locus_tag="MU580_10465"
     CDS             10001..13162
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-ii: DUF4135"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-ii: LANC_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1070: lanthionine synthetase C family protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:TIGR03897.1"
                     /locus_tag="MU580_RS10465"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MU580_10465"
                     /product="type 2 lanthipeptide synthetase LanM family
                     protein"
                     /protein_id="WP_246929397.1"
                     /sec_met_domain="DUF4135 (E-value: 6e-90, bitscore: 299.6,
                     seeds: 79, tool: rule-based-clusters)"
                     /sec_met_domain="LANC_like (E-value: 6.4e-44, bitscore:
                     147.7, seeds: 47, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTITAAELSLLQASRLRERRAATRADARPVPELTRAWRDDALVDD
                     GTHAAYLAGQLLDGDDLVALLAGDAWTPRAASADWLARVDPWLVHPPVSAEACAPANGH
                     LVVEDTRVAGLPFAALLGPMVGAQRAHLDGRPWLSRTATADLLDGLAERLATLSLRALL
                     AELARDPAPGRHARLDARLADPAHRAELLSRHPVLARDLVTAIGSWRAHVARILDRLHA
                     DHGDLVRMGLATERLDALEAVDLSSGDPHDGGQSVATLRFSDGSLLVYKPRDCRVFALY
                     RDLVDALAPALPGEIRLRAAAVLPRDGYGWVEFVAHAEDAASAIPLSRHLGRLGSLLAV
                     AHVLGASDLHLENVIASADGPVPIDLETLIQNRSEVDGEDGTALRRASRMLNASVLGSG
                     ILPVQLTTGEGTSIDVSVSTGGLHGAGTTATVHQVVDAATDRMRIEAREMPVGRSRNQP
                     PGATLARIRSGRAALADGYERTFRAIVERRAEVRAILSAAPDISSRHIVRATRSYSLLL
                     TEMRRPRPLRSGIDRDHLLRHLWTRVEEHPADAALVEAEERALWRLDVPLFSTRMDARA
                     LIADDEEAGPQRFARSTREDVLDRLARLTLDDLPESLRLVDESVLAATATPDGDDDARD
                     DARGRQAADATASLARAPRVDDDALREAARGQARILLASAVLGRDDATWIGVSSSLDSS
                     GLEYRPAGPTLYDGLAGIAFAATHAHGVLPGLGLDDLAGRAMHAVTAILDDWTRGLIDL
                     PVGAYSGATGLLHALAHHDARVGGDGHRDLRAAAVRRLGEVAHEDPHLDVMAGVAGACA
                     VVAGLPEGATEAGRHALRALAGRLMSTAVEVEGGALVWETGAERARLGGFSHGASGVGW
                     ALARTAGVLGDDAIADAAVRALRFDDALFDPSRRRWRDARPEARSAAGSFPAHWCHGTA
                     GIAMARADAAATLDRPDLLELALVGARETASDALPSDDSLCHGTLGNLIAVRGATRRTG
                     VDTGLAEFRDRALQRVLRAGPRSGLPEGVTSVRGLMLGTSGALYALCRELEPGIPDALL
                     LEGPR"
     gene            complement(13227..14537)
                     /locus_tag="MU580_RS10470"
                     /old_locus_tag="MU580_10470"
     CDS             complement(13227..14537)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012038656.1"
                     /locus_tag="MU580_RS10470"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MU580_10470"
                     /product="DUF2510 domain-containing protein"
                     /protein_id="WP_160469362.1"
                     /transl_table=11
                     /translation="MPDVPSAAPAGWFPDGSGQLRYWDGATWTQHVAPMVQAPAAPAPA
                     LSAAATAALAASQQVDAVHNAQAAEAAHDKAMRAAEAAQAKAVRAAEGEQQRAAKLAQR
                     EAAMHAKAAEREAAARDKSARAAAATVAMPVPPRQAAIAAPVAPAAPAPAPLLADTRPG
                     IHPAATWIVASVAALVILISAAGGGFRGMFVSVGLVALAAALYTVVFGRRGFVPALTSR
                     PRGTATAVGAVLLLIIGSALPAGASGSAPAPALAATASASPSPTPTPTATPTPVVHVVE
                     DVNAKTATDARTLLREAGYVVQYVLESGEATSVTDGMTVKSQSPVAGSRTDAGSTVTLT
                     LLAPAPTPTPEPTVAPTVAPAPQPAAPAPAPVAPAPAPAPAAPAPAPAPAPAPGRTITP
                     GAFCKKTEVGSVEKSDTGKSYRCGPDADGQRNRWYPM"
     misc_feature    complement(14689..14702)
                     /note="TFBS match to PsrA, Oleic acid responsive regulator,
                     confidence: weak, score: 18.23"
                     /tool="antismash"
     misc_feature    15262..15277
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: weak, score: 19.02"
                     /tool="antismash"
     misc_feature    complement(15762..15780)
                     /note="TFBS match to HgtR, Hydrogen-dependent regulator,
                     confidence: weak, score: 18.07"
                     /tool="antismash"
     misc_feature    15770..15786
                     /note="TFBS match to HexR, Glucose-responsive regulator,
                     confidence: weak, score: 17.63"
                     /tool="antismash"
     gene            complement(15826..17118)
                     /locus_tag="MU580_RS10475"
                     /old_locus_tag="MU580_10475"
     CDS             complement(15826..17118)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="MU580_RS10475"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="MU580_10475"
                     /product="hypothetical protein"
                     /protein_id="WP_143761559.1"
                     /transl_table=11
                     /translation="MFEYRLSVLPPVEPFPADVANTFFWHSKRSMPYFHANVGPQLAEY
                     GPVKIRNIDLVRIAAAVLAADRSASRSGSLSRWNQREISLTIDVLAVKPWDTVKKDLEQ
                     LLGFLTGDAWSLTFLRERGAAEQIGRLGIDAQRVVLLSGGADSATGALLSALELVPLSQ
                     KHILVSHWSSTNLSPLQTRVANEIERLAPGAKADHVKVNIARGKHAPDGTAYGRENSTR
                     SRSFLFIALGLAIASVDELPLWLPENGYASINPPLSKSRRGSLSTKTTHPKFLAGLRRI
                     LKAVGAHYDVHNPYADLTKGEMFSKVADAVGVDEASTYLTLTSSCSHTGARTYGTAPNV
                     ACGVCFGCVLRRASFTASGLNDGSQYFLPKDDGQQNWVATKSVVPAMRDFLSESFSVAQ
                     LAHLQIPSDIPLARVESLVERGREELRQLAL"
     misc_feature    complement(15829..15831)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     misc_feature    complement(16225..16227)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     misc_feature    complement(16294..16296)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     misc_feature    complement(16663..16665)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     misc_feature    complement(16699..16701)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     misc_feature    complement(16726..16728)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     misc_feature    complement(16813..16815)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     misc_feature    17117..17132
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: weak, score: 17.83"
                     /tool="antismash"
     misc_feature    complement(17120..17135)
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: weak, score: 16.81"
                     /tool="antismash"
     gene            complement(17121..17546)
                     /locus_tag="MU580_RS10480"
                     /old_locus_tag="MU580_10480"
     CDS             complement(17121..17546)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="MU580_RS10480"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="MU580_10480"
                     /product="hypothetical protein"
                     /protein_id="WP_143761560.1"
                     /transl_table=11
                     /translation="MDFDWLSSLPSRSELVRAILDMVCDADMGSDIPAEEQREIAAHLL
                     DWMLDTEINPTPPDAVATAEHAIGLIVAEIFLSEAGEFTSIEGTSREEFVDGVYETSQH
                     LAAGSNLSQTGASQAEIDKAIERGLKWLRRTHAKDNG"
     CDS             17655..17783
                     /gene="allorf_2244227_2244355"
                     /locus_tag="allorf_2244227_2244355"
                     /protein_id="allorf_2244227_2244355"
                     /tool="antismash"
                     /transl_table=1
                     /translation="MLLMSLTSLPASATATATATATATRSCTCTCTCTCTGESWNI"
     CDS_motif       17655..17690
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence: MLLMSLTSLPAS"
                     /locus_tag="allorf_2244227_2244355_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       17691..17783
                     /prepeptide="core"
                     /locus_tag="allorf_2244227_2244355_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class II"
                     /score="-7.00"
                     /molecular_weight="2768.1"
                     /monoisotopic_mass="2766.2"
                     /core_sequence="ATATATATATATRSCTCTCTCTCTGESWNI"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MLLMSLTSLPAS"
                     /leader_location="[17654:17690](+)"
                     /alternative_weights="2786.1"
                     /alternative_weights="2804.1"
                     /alternative_weights="2822.1"
                     /alternative_weights="2840.1"
                     /alternative_weights="2858.2"
                     /alternative_weights="2876.2"
                     /alternative_weights="2894.2"
                     /alternative_weights="2912.2"
     misc_feature    complement(17771..17784)
                     /note="TFBS match to PerR, Peroxide regulator, confidence:
                     weak, score: 14.53"
                     /tool="antismash"
     CDS             complement(17780..17920)
                     /gene="allorf_2244352_2244492"
                     /locus_tag="allorf_2244352_2244492"
                     /protein_id="allorf_2244352_2244492"
                     /tool="antismash"
                     /transl_table=1
                     /translation="MWVLARPIRALLARCQLAFATVFTSGPSHRKVTARLLCQRASSPK
                     R"
     CDS_motif       complement(17861..17920)
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence: MWVLARPIRALLARCQLAFA"
                     /locus_tag="allorf_2244352_2244492_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       complement(17780..17860)
                     /prepeptide="core"
                     /locus_tag="allorf_2244352_2244492_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class II"
                     /score="-6.70"
                     /molecular_weight="2758.2"
                     /monoisotopic_mass="2756.6"
                     /core_sequence="TVFTSGPSHRKVTARLLCQRASSPKR"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MWVLARPIRALLARCQLAFA"
                     /leader_location="[17860:17920](-)"
                     /alternative_weights="2776.2"
                     /alternative_weights="2794.2"
                     /alternative_weights="2812.2"
                     /alternative_weights="2830.3"
                     /alternative_weights="2848.3"
                     /alternative_weights="2866.3"
     misc_feature    17823..17838
                     /note="TFBS match to ColR, Phenol-responsive regulator,
                     confidence: weak, score: 17.76"
                     /tool="antismash"
     gene            complement(17921..19810)
                     /locus_tag="MU580_RS10485"
                     /old_locus_tag="MU580_10485"
     CDS             complement(17921..19810)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF019313.4"
                     /locus_tag="MU580_RS10485"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MU580_10485"
                     /product="P-loop NTPase fold protein"
                     /protein_id="WP_160468770.1"
                     /transl_table=11
                     /translation="MSKASHPLFLDEPTDVDLLSFDAVASTVVDAVLDPRLDPIALGLS
                     GAWGSGKTSVLRLIGRQLRTPEGAKPTCLVIETDPWRYDPQLGIKESLIGEILTSIEQA
                     LPDDGVGEKSKAILTRLLRRVDWTKAMKLAATSAITVSLPSLSSVLDLVKPRNDVEGEE
                     QPEPITDMVQFRAEFKNLLESEGLSSIENVVVLVDDLDRCLPDTVVETLETIRLFLSVP
                     KMSFVIAADEARVADAIATRYPSSDSNNGEESPARLYLHKIVQTSVPVPALSDFDTEAY
                     LVLLQVQSLVATNDEYEGIVGEVADARRNAVSLETVGSLQRADFAEQRNNAARIRPIIH
                     EKTRGNPRRIKRFLNDLSVRLSIAAKRGIALDEATIAKLMVLEQYFPDAFKTLTDWLRE
                     RTLRTNLEALEAFAGTPEATDQPDPSEVTDDAPAIKAPPAPKADATSRSTTAVGTPEKK
                     PPFSDGLIRWARLSPALAKKDIAPYLVFAASFKNLFVESDALPESIRDMATQLLSRSPG
                     EARRVTDEMLIKLQVSDARSLVSYMGGVTVDEPQRQASGIIAMLRVSRVQPQAVDSVVN
                     ALRRIKPSELKVASLTTLKVTDAPAILSQFDAMAVASGRSELTNALSAVKEDV"
     gene            complement(19807..20184)
                     /locus_tag="MU580_RS10490"
                     /old_locus_tag="MU580_10490"
     CDS             complement(19807..20184)
                     /GO_function="GO:0000287 - magnesium ion binding [Evidence
                     IEA]"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0009036 - type II site-specific
                     deoxyribonuclease activity [Evidence IEA]"
                     /GO_process="GO:0009307 - DNA restriction-modification
                     system [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF018339.4"
                     /locus_tag="MU580_RS10490"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MU580_10490"
                     /product="BsuBI/PstI family type II restriction
                     endonuclease"
                     /protein_id="WP_246929398.1"
                     /transl_table=11
                     /translation="MLEATCWAEAKNPRLDDRESHDWICAQLCFPIAENTRETDRRQAL
                     RQFWYAGLTILKETHSSLIRLFGGSSAGLVYVSCFPYHAMTRQLVVDLALEAQAWCAMD
                     PPHNIHLKGDVLMGPHEVRAS"
     misc_feature    complement(19852..19854)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     misc_feature    complement(19996..19998)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     CDS             20251..20373
                     /gene="allorf_2246823_2246945"
                     /locus_tag="allorf_2246823_2246945"
                     /protein_id="allorf_2246823_2246945"
                     /tool="antismash"
                     /transl_table=1
                     /translation="MRVWVCSPVRKPSHGGKAERRVRRCTIRRPVLPIQFSRRR"
     CDS_motif       20251..20298
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence: MRVWVCSPVRKPSHGG"
                     /locus_tag="allorf_2246823_2246945_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       20299..20373
                     /prepeptide="core"
                     /locus_tag="allorf_2246823_2246945_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class II"
                     /score="-6.00"
                     /molecular_weight="3014.6"
                     /monoisotopic_mass="3012.8"
                     /core_sequence="KAERRVRRCTIRRPVLPIQFSRRR"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MRVWVCSPVRKPSHGG"
                     /leader_location="[20250:20298](+)"
                     /alternative_weights="3032.6"
     CDS             20291..20491
                     /gene="allorf_2246863_2247063"
                     /locus_tag="allorf_2246863_2247063"
                     /protein_id="allorf_2246863_2247063"
                     /tool="antismash"
                     /transl_table=1
                     /translation="MGVKLNGVCVDAPYGGPSCPSSSLDAVDRDRTTAAMMCSTVSCAG
                     SCSRYRRTVRRRPWRLAVALT"
     CDS_motif       20291..20398
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence:
                     MGVKLNGVCVDAPYGGPSCPSSSLDAVDRDRTTAAM"
                     /locus_tag="allorf_2246863_2247063_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       20399..20491
                     /prepeptide="core"
                     /locus_tag="allorf_2246863_2247063_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class II"
                     /score="-4.30"
                     /molecular_weight="3317.9"
                     /monoisotopic_mass="3315.8"
                     /core_sequence="MCSTVSCAGSCSRYRRTVRRRPWRLAVALT"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MGVKLNGVCVDAPYGGPSCPSSSLDAVDRDRTTAAM"
                     /leader_location="[20290:20398](+)"
                     /alternative_weights="3335.9"
                     /alternative_weights="3354.0"
                     /alternative_weights="3372.0"
                     /alternative_weights="3390.0"
     misc_feature    complement(20360..20374)
                     /note="TFBS match to MexT, Global virulence regulator,
                     confidence: weak, score: 17.3"
                     /tool="antismash"
     misc_feature    complement(20370..20383)
                     /note="TFBS match to ANR, Anaerobic transcriptional
                     regulator, confidence: weak, score: 20.35"
                     /tool="antismash"
     misc_feature    20548..20564
                     /note="TFBS match to GnfM, Regulator of nitrogen-fixation
                     genes, confidence: medium, score: 22.46"
                     /tool="antismash"
     misc_feature    20804..20817
                     /note="TFBS match to PerR, Peroxide regulator, confidence:
                     weak, score: 15.19"
                     /tool="antismash"
     misc_feature    complement(20807..20820)
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 14.1"
                     /tool="antismash"
     CDS             complement(20809..20949)
                     /gene="allorf_2247381_2247521"
                     /locus_tag="allorf_2247381_2247521"
                     /protein_id="allorf_2247381_2247521"
                     /tool="antismash"
                     /transl_table=1
                     /translation="MGQRAVAQLGSALDWGSRGRRFKSCQPDGHASEGPMGPAGAFVIL
                     G"
     CDS_motif       complement(20917..20949)
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence: MGQRAVAQLGS"
                     /locus_tag="allorf_2247381_2247521_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       complement(20809..20916)
                     /prepeptide="core"
                     /locus_tag="allorf_2247381_2247521_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class II"
                     /score="-5.70"
                     /molecular_weight="3575.0"
                     /monoisotopic_mass="3572.8"
                     /core_sequence="ALDWGSRGRRFKSCQPDGHASEGPMGPAGAFVILG"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MGQRAVAQLGS"
                     /leader_location="[20916:20949](-)"
                     /alternative_weights="3593.0"
                     /alternative_weights="3611.0"
     tRNA            complement(20867..20940)
                     /anticodon=(pos:complement(2247476..2247478),aa:Pro,
                     seq:ggg)
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /locus_tag="MU580_RS10495"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /old_locus_tag="MU580_10495"
                     /product="tRNA-Pro"
     gene            complement(20867..20940)
                     /locus_tag="MU580_RS10495"
                     /old_locus_tag="MU580_10495"
     gene            complement(21014..21553)
                     /locus_tag="MU580_RS10500"
                     /old_locus_tag="MU580_10500"
     CDS             complement(21014..21553)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012038659.1"
                     /locus_tag="MU580_RS10500"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MU580_10500"
                     /product="hypothetical protein"
                     /protein_id="WP_246929400.1"
                     /transl_table=11
                     /translation="MDQLLSRLDRIAAGRQAGHIIAEDMRDHPWTTRAFRWIRWILIAE
                     TAVGATAVAIALTLASDGIAVAPAVWFRSFVVLAMTITLYYFAWRASAGYWWAYSRLRL
                     FSQIFPIVTLVVAAIPGLYPLWMVIEQIVFSLLLIGVADILRSDHMRDAFPKPGRVAAS
                     AAPDPSAPGRPGGAPA"
     misc_feature    complement(21537..21552)
                     /note="TFBS match to RutR, Regulator of the pyrimidine and
                     purine metabolism, confidence: weak, score: 19.44"
                     /tool="antismash"
     misc_feature    22241..22255
                     /note="TFBS match to NrdR, Represses ribonucleotide
                     reductase encoding genes, confidence: medium, score: 22.0"
                     /tool="antismash"
     misc_feature    22625..22639
                     /note="TFBS match to IolR, Regulator of the inositol
                     catabolism, confidence: medium, score: 18.48"
                     /tool="antismash"
ORIGIN
        1 ccgcgtgtag gcggaggccg gcgacgcgag cacgcgcgcg gccggtcccg tctcctgcac
       61 gcggccgcgc tgcatcacga ccacctcgtc ggcgcgctcg gcggcgaccg ccaggtcgtg
      121 cgtgatcatc agcagccccg cgccggtctc ctcgcggagc cggtcgagca ggtcgagcac
      181 gcggcgctgc acggtcacgt cgagggcgct cgtgggctcg tcggcgatga tcagctccgg
      241 ctcgagcgcg atcgccgcgg cgatgagcac gcgctggcgc atgccgccgg agagctcgtg
      301 cgggtgctgc cgggcgcgcg tctccgggtc gtcgatgccg acgcgctcga ggaggtcgag
      361 cacgcgggcg cggttccgac ggcggtcgcg ggatccgtgg atccgcagcc cctcggcgac
      421 gctcgccccg atggtggcca cggggtcgag ggagctgccc ggatcctgcg gcacgagccc
      481 gatgcggcgc ccgcggatgc cgcgcagccg cgactccccg atgccgacca gctccgtgcc
      541 gccgagcgcg atgccccctc ccgcgatggt gccgttgcgg gcgaggagcc cgaccacggc
      601 ctgcgcgacg gacgacttgc cggacccgga ctcgccgacg agcgccgtga ctcgtcccgc
      661 ggtgacctcg aaggagacgc cgtcgaccgc gcggcgggtg cccgccgccg tccggtagtc
      721 cacctgcagg tcgcgcacgg cgaggagcgg atgcgtggga tcggtcatgc gagctgccct
      781 ccgcggatcg actggctgat gcggttggtc gcgagcacga cggccacgac cacggcgccc
      841 gggagcaccg tgagccacca cgcggtggcc acgtagtcgc ggccctccgc gacgagcagg
      901 ccccactcgg gcgtgggcgg cggggcgccg tagccgagga agccgagcgt ggagatctgc
      961 aggatcgcgg atccgaactg gagggccgcg agcgcgatca cgggcgtgag cgagttcggc
     1021 agcacgtgcc ggcgcagcac ctgcacgagg gtgccgccgg atccgtacgc cgcctcgacg
     1081 tactcgctga tccgcacgcg caccacctcc gcccgcgaca gccgcgcgaa cacggcgatg
     1141 gacgtgacac ccaccgcgat cgcggcgttc gtggtgccga agcccagcag gatcacgatg
     1201 ctcaagctga gcagcaggcc cgggatggcg agcagcacgt cgacgagccg catgagcacg
     1261 tcgtcgacga tgccgccgac cgtgcccgcg accacgccga ggagcgtgcc gacgacgaga
     1321 ccgacgagca ccgcgacgac cgcgccgacg accgactgcg acgccccgaa cacgacgcgc
     1381 gtgtagaggt cgcggccggt ggagtcggtg ccgaaccagt gcgcggcgct cggcgcctgc
     1441 agcgacggcg cgacggacgc ggtcgggctg ccggacgcga agaggccggg gacgagcgcc
     1501 cacagcagca tcacgagcac gacgaggaca gggatcacga ggccgccggc gaggcgcgcc
     1561 cggctgcggg gacgcgcgcg gggcgcgtcg atggtggcga gcgtggcgct catcgcgcac
     1621 ctcctctgcg caggcgcgcg tcgagaacgg ggtagagcag gtcgaccgcg aggttgatca
     1681 cgacgtaggc gaccgtggag agcacgacga ccgcgagcag caccggactg tcgcggctcg
     1741 cgaccgcctg cacggtgagc tggccgacgc ccgcgcggcc gaacacggcc tcggtgacga
     1801 ccgccccgcc gacgagctcg ccgaacagca gcccggccat cgtcagcgtg ggcagcagcg
     1861 cgttccggcc gacgccgtgc agcagcagcc acggcgtgcc ggcgccgcgg gcccgcacca
     1921 cctcgacgaa cggcatggcc gacacgtcgt cgatgctgcg gatgagcacc tgcgcgagcg
     1981 gcgccgcgat cggcacggcg atggtgagca cgggcaggat cagcgcctcg ccggggctcg
     2041 cgccgatgat cggcaccagc ccgagccgga acgacagcac ctggatgagg atgatcccca
     2101 cccagaacac gggcagcgag acgagcagcg gcggcaggtc gcggaagacc cgacggatcc
     2161 acctggcaca gccgtacgtc gcgaggaacg cgatcggcac ggccagcacc acggcgacca
     2221 ggaggccgag caccgcgagc acgagcgtcg acgggatcgc ggtggcgagc agcgtcgaca
     2281 cggccgcgcc gctctgcacc gagtacccga gctgcccctg cgcgaacgcg gcggcggact
     2341 cgccgagccg cacgatcagc ggccggtcgg caccgtagga ctcgcggatc gcggcgagct
     2401 gctccggcgc gaggccgagc tccgggctgc cgtagcgggc gagcaccgcg tcgccgggga
     2461 gcgcggcgag cagcacgtag gccacgacgt aggcgaggac gagcacgatg acggcctgcc
     2521 cggcgcgccg gatggcgtag ctcatcgcgg tcccccgccc gtcgacaggg gaaggacgcc
     2581 ccgcatcagc ggtcgagcca gacgcccgcg aacactgggc ggccgaccga ctcggtggcg
     2641 aagccccgca cgtcgccgcg gaggccgtag acctggggct cctcgaacag cggcagcacg
     2701 taggcctggt cggcgatgcg ctgctgcgcc gcctccgacg cggcctgccg gccctccgtc
     2761 gtgggctccg acgcgatgcg ggtgaggagc gcgtccagct ccgggtcggc gatgctgccg
     2821 tccgcggggt tccggttgag cagcacgttg cggttggtgg aggagtactg cgacttgagg
     2881 acgtcgtagt ccgagcggcc gaccatcgag tggtacgcct cgagcgcgtc cgggtcctgc
     2941 gaggccttcg tctgggcggc ctggtcgccc gagaacagct ccacctccac gccgatctcc
     3001 gcgagctgcg actggatcag cgtcacgacc tccttggagc gcggctgcgg gagcgcctcg
     3061 ttgacgacga gctccagctt ccgtccgtcc ttctggcgga tgccgtcgga tccggggacc
     3121 cagccggcct cgtcgaggag cgcggcggcc ttgtcggcgt catgcgcgta gtacgaggag
     3181 gtgtcgacgt agccgagcgc gctcttcgcg agcacgccgg tcgcgagcgg gtagctgtcg
     3241 ctgaagaggg tgtcgaggat cgcctgccgg tcgacgcccg cgatgatcgc ctgccggacg
     3301 cgcacgtcct cgagctgcgg cgtgcggaag cggaggttga tgccgttgtc gacgccgttg
     3361 gtcgccgccg cgacgagctg gaggtcgccc gtgcggaact gcgcctcgtc gggcgcctcg
     3421 atctgccggg cgacgtcggc ctgcccggcc acgaccgtgc cgacccgcac gctgtcctcg
     3481 gcggcgacga tgaggtccac cccgtcgacg agcggccggc cctggtgggc ggcctcgggc
     3541 ggcgcccagt cgtagtcctc gcgggcggcg agctggatct gcgtgcccac cgactccccg
     3601 gacaccgtga acggcccgct gccgatgacc gtctccgcct gcccgggccc gaaaccgtcg
     3661 tcggccttgg cgagcgtcga gtcggacacg agccccgagt tgatggtcga ggtggcctgc
     3721 gcgaagccgg gcgcgggagc cgtgaagtgg aacctgacgg tgtccgcgtc gacgacctcg
     3781 ccgcggtcgt agttgttgat cgcctcgctg acggtgagcg ctcggtcgac gtcgcccttg
     3841 ccgtagaggt cgaagttcgc gacgacgttc tgggcggtga gcggggtgcc gtcggagtag
     3901 gtcacgtcgg tgcggatgtc gaacgtgtac tcggtcgcgt cggcgttcac ctcgggcagc
     3961 gccgtcgcga tccacggctc gagctcgagc gtctccgggt cctgccagag cagccggtcg
     4021 gtgatgttgt tgacgacggc gccgttcggg tagaagccgg cggccggcgg gtagagcgtc
     4081 gtccaggtct gcggctcgag gtaggtgagc gtgccgccgg ccttcggttc gccgctcgcc
     4141 gcttgatccc ctccgccgcc cgccgagcac ccggccatca gaccggtcgc cgcgacgagg
     4201 gcggtgaggg cgatgacggg gcggggagga cgaggcatgg ttctgctcct gcgtgtgctg
     4261 tgcgtggatg ggtgagacga ctccaacacg catgcagggt cttcgcaggg ccgcggaaca
     4321 cgcggcgtaa cggggtgcaa cgcggcgtca cgcggggaat gccacccgcg tgctcgccgt
     4381 tgcggcggcg gcgtgacgcc tcgccgccgt cgactccgct gccggatgcc gacgccctct
     4441 agggttccgg gatgaccacg cccccccccg tccgccccgc cgtgcccgac gacgccgacg
     4501 ggatcgccga ggtccacatc cgcacctggc aggagacgta cgcgcacctg ctgccggccg
     4561 cgtacctcga cggcctggac gtcgcggcgc gcgccgagca gtggcggggc tcgctgggtg
     4621 acccttccgg ggctccgacc ttcgtcgccc tcgacggcga ccgcatcgtc ggtttcacgc
     4681 tcgcgggacc ggcgcgcgac gaggatccgc cgcgcccctt ccagctctac gcgatcgacg
     4741 tggtcgcgtc cgcccacggc acgggcgccg gccaggcgct gttcgacgcg gccgtcggcg
     4801 actcccccgc ctacctctgg gccgccgacg acaacccgcg cgcggcggcg ttctaccgcc
     4861 gcaacgggtt cgtgcgcgac gggggcgtcg agcggcagac gtaccagggg gcggagatgg
     4921 tcacggtgcg gatggtgcgg tgagggtgcc ggcgggcggc gcacggcccg gcgcgccgct
     4981 cagcgcagct tgaccacgcg gatcgccgcc agggtgagga ggacgacgag cgccgcgagg
     5041 cccacgctcg tcgcgaggag cggcagggtg tccgccgccg tgaggccccc ggatcccgcg
     5101 atcgccgtcg accccaggtt cagcgcccgg gtgttgatcg cctgcgggag cacctccgcc
     5161 agcggacgca gggccgccga ggtcacggcg gcgacgcccg cgacgcaccc gacgaggcac
     5221 agcgcgaccg gcgccgcgaa ggaccgcagg agcagcgaca gcagggactg gacggcgatg
     5281 aggggcagcg ccgccacggt cgcgatcagc cccacgagga ggaacgcgac ggggaacggg
     5341 ccgtccagcc ggagcacgaa cagcccggac accgccgtgc cgccgacgag caccgcctgc
     5401 atcagcgcca ccggaacgag gatcgccacg atcttcgcca gcacgagtcg gatcggtcgc
     5461 gcggtcgccg tcagcagggc gttccagttg gtgccgcggt gctcgacgcg ccagatggcc
     5521 gccgcgagca ggctgatgcc catcgagtag aagagcaggc cgtagaacag caccacctgc
     5581 gaggtgaagg acgcccaccc ggagtccagg gtctgcgtgt tgttcgccag gttgatggtg
     5641 ccggtgacga ctgccaggag cggcagcagc accgcgatga tccagatgct ggagcgcttg
     5701 agcttcacgg cctcggctcg gaacacgccc gtcacctctc cacgcggtcg agccggatcg
     5761 tcgcgagcgc gaaggccgcc gcgaccacga cgaggaagcc ggcgatccac ccgagcgggg
     5821 aggcgacgta gcccacgccc gcgtccgact ggccggcctg cgagatgacg gcgtagtacc
     5881 cccacgggat ggcgcggctc gcgacggacg ggagcaggag ggagaagacg gccaggaagg
     5941 cgcccagcat ccccacgccc acgctgatga gctggttctc gacgcgcgcc gcgagccaga
     6001 cgtgcagcgc gcagaacgcc acgtcgacca ggtagagcag gagcgtgtac agcgcccacg
     6061 gccccacctc gacgggcacc cggatcccgg cggcgtaccc ggcggcgatc acgagcagcg
     6121 attggatcag cacggcgggc acgaggagca ccgcgagggc cacgagcttg gcccggcaca
     6181 gctcccccgc cgtgcgtccc gcgcccgccg cgaggatcca cccgcccgcc tggtgctcga
     6241 tgtcggtctg gcggctcgcg atcaccgcgg tgaggatcgg cgaggtcatc gccgccatga
     6301 gcgtgtagcc gagcaggagc gcggcccagg ggtgcgcgcc cggatcgtcg aagcccgcgc
     6361 gcgtgctgcc cgcgaactgc gacgccgagc tcagggcggc gacggccacc accatgccga
     6421 tgagcagcgg gagcgagcgg agccggtgca tcttgcggaa ctcgatcgcc acggcgcgcc
     6481 tcacagctgc cccccgcgcc cggtgatgtc catgaacacg tcctccaggc tctgcggcag
     6541 ccgccgcacc tcgtgcacgg gcacgtcggc cgccacgagc cggcgcacga tgtccgcggt
     6601 ctcgtccttg gagcgggcgc tgagccggat cccctccggg ctcctggccg ccccggcgac
     6661 ctccgccatg gcccggtccg gcgcggacgt ctcgatgacg aggtcgggga tggagtgctc
     6721 gaacagctcg gcgcgcgtgc cctggaagat catccggccg tcggccagga tgccgagcac
     6781 gcccgccatc ttctcgatct cgtcgaggag gtggctggag accatcacgg tgatgccctg
     6841 gccggccagg tccatgagga gggagcggac ctcctcgatg cccgccggat ccagcccgtt
     6901 ggtgggctcg tcgaggacga gcagcgaggg gtcgcgggcg agggccatgg cgatccccag
     6961 ccgctgcttc attccgagcg agtaccggcg caccagcttg tcgcggtgct gcgtgagccg
     7021 cacggtcgcg aacgcccgct ccacctgggc ctccgcgagc ccgagcatgt cgcgcacgat
     7081 ccgcatgttc tcccaccccg tgaggtggcc gtagccggcg ggcgcctcga tcatggagcc
     7141 gatggacggc aggagcccgc cgcgcgtcgc cggcgtgagc cgctggccga acaggtggat
     7201 ctcgcccgac gtgggctgcg tgagcccgag cagcatcttc atggtcgtgg acttgccgga
     7261 gccgttgggc ccgaggaacc cgtacacgga gccctgcggc acctcgatgt cgagcgcgtc
     7321 gacggcgacg tgatcccgga accgcttggt gagcccgcgg gtggcgatga cggcgctcat
     7381 cggcgcgggg gtgtcgtggt cggcatgccc ccatactcgg ccggccgccg cgcgggcgca
     7441 tcgtgccgtg ggccggtccc gcccggtccc ctctcctgcg atgggaggag cgggtggcag
     7501 gtcggcggga ccgcgcccca tgcgccgcag cggtcaggcg gcgaggcccc gccggtgcgc
     7561 ccagatcacc aggtggacgc ggtcgcgcac ggcgagcttg gtgaggatgt gcccgacgtg
     7621 cgtcttcacc gtgacctccg cgatggacag gtcgcgggcg atctccgggt tggacgcgcc
     7681 cgtgacgagg cgcgtgaaca cgacccgctc ccggtcggtc aggacgtcga gcgcggcggt
     7741 gtccgggtcg ggcggcgccg tcctctcgac ggccagccgc tcgaggagcc gctgcgtggt
     7801 gctcatcgag gcggcgaacg tgccgttgtg cacggaccgg atcgcgtcga ccagctgcac
     7861 ggcggtgctg tccttcagca ggaagccgac ggcgccggcg cgcagcatcc ggatggcgta
     7921 ggagtccgtg tcgtgggtgg tgagccccag gatccgcgtc ccctcggcgc gcccgccctc
     7981 cacgagccgg cgggtcgcct cgatgccgtc gaggaccggc atgcggacgt ccatgagcac
     8041 cacgtccggg cggagctcga cgacgcgggc gacggcctgc tcgccgtccg cgcagacgcc
     8101 gaccgcggcc atgtccggct gcgcgtccac gatgcgggcg aagccatccc gcacgaggga
     8161 ctggtcgtcg accacgacga cccggatcgg cgcgggcgcg tcggtcacgg ggtgctcccg
     8221 ccgagcggcg cggtcggcca ccgcgcctgg aggacgaact cgtcgtcgca cgcgtaccgg
     8281 gcctgcccgc cgtagagcgc gcagcgacgg cggatcgcgg cgaggccccg gtgctcctgc
     8341 acggggcatc cccgcttgtc gcgaaccacg gcattggcga cggtgatcgc cagcgcgtcg
     8401 ggcgaccact cgacgcggag gcgcgcggtg ccgcccgcgc cgtgccgcat ggcgttcgtg
     8461 agggactcct gcacgacccg gtagacggcg aagcccacgc ccggcaggag gggtcgcggc
     8521 gagcccgcgt cctgcctgtc gatgccgagg ccggagccgc ggaagccctc gacgagggcg
     8581 tcgacgtcgt cccagccggg gatgggacgc acgtccgcgt cggcgtcggt gggcgcgagc
     8641 agcccccgca cctcgtgcag ggcggcccgg ctggtctcgg agatggtgcg gaacatgcgc
     8701 gacgcctcgg ggctcggcgc ggtcgcccgg ccgctctccg cctggacgat gacgctggtc
     8761 agagtgtgcg ccagcacgtc gtgcatgtcg tcgctgatgc gctcgcgctc ctcgtaggcg
     8821 gcgagccgcg tccgggcgtc cgcgtcgcgt tcggacagcg tcgtccggag ctcggcggtg
     8881 cggacggcct cgctgcggcg ccgttcgagc agaccggccg cccacgcgac cgcgaagctc
     8941 acggacacga gcgcgatgac catgccgacg gatcccgtgg agcccagctc ccctccggtg
     9001 agggtgcgcg cggcgaggac gaccacgaag cacgcgccga gggcgagccc gacgtgccgg
     9061 agccggtccg cggcgtgggc ggcgacggag taggccgcca ccaggagcac gacgtcaccc
     9121 gggaacagga gcgagctcgt cgcgagcatg tgcgccgacg agatcgccgt agccagcagc
     9181 gcggcggtga cgggccgcgc gtggcgcacc gcgagcgtga gcgccatgag ggacgaccag
     9241 atccagtcgg gctggcccag gacgcccatg atggcgcaca ggactaccgc agcgcccgcg
     9301 acgacctggt cgccttgcgc gcgcagactc ccccgtcgca tcacgtcctc aggctagcgg
     9361 ggaggacacg cccggccgcc ggcggacgcc ctccccccgg ccccccgtcc gcggggcatc
     9421 ccggtcgcgg cctccgacga tgggcggagg gcacggccgc ggatgtcatc gggtcgcacg
     9481 atgcgctcgg acggaagccg ctgggaacgt gagcaccagg gatcgcgtac gggctgcgcg
     9541 tcgacgccgc accggccgag gcgcacggat ccgcgatccc cacggggcaa gtcggacctg
     9601 tgacggccca tgggccatcg ggatgggtgc ggctcgcacc acgacggtct gggccgaccg
     9661 gccgggatcc atgcgcgaca acaggaacac aggtggaaca cgatgaacga catcctcgag
     9721 acggagaccc ccgtcatggt cagcccccgg tgggacatgc tgctcgacgc gggcgaggac
     9781 accagcccgt ccgtccagac ccagatcgac gcggagttcc gtcgcgtcgt gagcccgtac
     9841 atgtccagca gcggctggct ctgcacgctc accatcgaat gcgggacgat catctgcgcg
     9901 tgtcgctgac ggacgccctc gacggacggg ccgcgctcgg cgcgcggtcc gtccgctccg
     9961 cgtcgggccc cgcccgccgg agcggcgagg gggatccgac gtgacgatca ccgcggccga
    10021 gctctcgctg ctgcaggcgt cccggctgcg cgaacggcgc gcggcgacgc gggccgatgc
    10081 ccgaccggtc cccgagctga cgcgtgcctg gcgcgacgac gccctcgtcg acgacgggac
    10141 gcacgccgcc tacctcgccg ggcagctgct ggacggcgac gacctcgtgg cgctcctggc
    10201 gggcgacgcg tggaccccgc gggccgcgag cgcggactgg ctcgcccggg tcgacccctg
    10261 gctcgtgcat ccgccggtct ccgcggaggc gtgcgcgccg gcgaacggcc acctcgtcgt
    10321 cgaggacacc cgcgtggccg ggctcccctt cgccgccctg ctcggcccga tggtcggcgc
    10381 gcagcgcgcg cacctggacg gtcgcccgtg gctctcgcgc accgcgaccg cggatctcct
    10441 cgacggcctc gcggagcgcc tcgcgaccct ctccctccgg gccctcctcg cggagctcgc
    10501 ccgggatccg gcaccgggtc ggcacgcgcg gctggatgcg cggctcgccg accccgcgca
    10561 ccgcgccgag ctcctctccc gccaccccgt cctcgcgcgc gacctcgtca cggcgatcgg
    10621 cagctggcgc gcgcacgtcg cgcgcatcct cgaccgcctg cacgccgacc acggcgacct
    10681 cgtccggatg ggcctcgcga ccgagcggct cgacgccctg gaggccgtgg acctgagctc
    10741 gggcgacccc cacgacggcg ggcagtccgt cgcgacgctg cgcttctccg acggcagcct
    10801 gctcgtctac aagccgcgcg actgccgggt gttcgcgctg taccgcgacc tcgtcgacgc
    10861 gctcgcgccc gccctccccg gcgagatccg cctgcgcgcg gccgcggtgc tgccgcgcga
    10921 cgggtacggc tgggtcgagt tcgtggccca cgccgaggac gccgcctccg cgatccccct
    10981 gtcccggcac ctcggccggc tcggctcgct gctcgccgtc gcgcacgtgc tcggcgcatc
    11041 cgacctccac ctcgagaacg tcatcgcctc cgcggacggt cccgtgccca tcgacctgga
    11101 gacgctgatc cagaatcgca gcgaggtcga cggcgaggac gggacggccc tgcgccgggc
    11161 gtcgcggatg ctcaacgcgt cggtgctggg cagcggcatc ctcccggtcc agctcaccac
    11221 cggggagggc acgagcatcg acgtcagcgt cagcaccggg ggcctgcacg gcgcggggac
    11281 cacggcgacc gtccaccagg tggtggacgc ggccacggac cgcatgcgca tcgaggcgcg
    11341 cgagatgccg gtcggccggt cgcgcaacca gccgccggga gcgacgctgg cgcgcatccg
    11401 ctccggtcgc gccgccctcg cggacgggta cgagcgcacg ttccgcgcca tcgtcgagcg
    11461 ccgggcggag gtccgcgcga tcctgtcggc cgcgcccgac atctcgtcgc ggcacatagt
    11521 gcgcgccacc cgctcctact ccctgctcct cacggagatg cgccgacccc gcccgctccg
    11581 cagcggcatc gaccgggacc acctcctccg ccacctctgg acgcgcgtcg aggagcatcc
    11641 cgcggatgcc gcgctggtcg aggcggagga gcgcgccctc tggcggctcg acgtgcccct
    11701 gttctccacg cgcatggacg cacgcgccct catcgccgac gacgaggagg ccgggccgca
    11761 gcgcttcgcg cggagcacgc gcgaggacgt gctcgaccgg ctcgcgcggc tcaccctcga
    11821 cgacctcccc gagtccctcc ggctggtcga cgagtccgtg ctggcggcga ccgcgacgcc
    11881 cgacggagac gacgacgccc gcgacgacgc gcgaggacgg caggccgcgg acgccaccgc
    11941 ctcgctggcc cgcgcaccgc gggtggacga cgacgccctg cgggaggcgg cacgcggaca
    12001 ggcccggatc ctcctcgcct ccgccgtcct cggccgggac gacgcgacct ggatcggcgt
    12061 gagcagcagc ctcgacagca gcggcctcga gtaccgcccc gcggggccca ccctgtacga
    12121 cgggctggcc gggatcgcgt tcgccgcgac ccacgcgcac ggcgtgctgc ccggcctcgg
    12181 gctcgacgac ctggccggcc gggcgatgca cgcggtcacg gcgatcctcg acgactggac
    12241 gcgcggcctg atcgacctgc cggtgggcgc ctacagcggc gcgaccgggc tcctccacgc
    12301 gctcgcccac cacgacgcgc gagtcggcgg agacgggcac cgcgacctcc gggcggcggc
    12361 cgtccgacgg ctcggcgagg tggcccacga ggatccgcac ctggacgtga tggcgggcgt
    12421 cgccggcgcg tgcgccgtcg tcgcggggct gcccgagggc gcgaccgagg cgggccgcca
    12481 tgcgctgcgc gcgctcgcgg ggcggctgat gagcacggcg gtcgaggtgg agggcggcgc
    12541 cctcgtctgg gagaccggtg ccgagcgggc gcggttgggc gggttctcgc acggcgcatc
    12601 cggcgtcggc tgggcgctcg cccgcaccgc cggcgtgctg ggcgacgatg ccatcgccga
    12661 tgcggccgtc cgcgccctgc gcttcgacga cgcgctgttc gacccgtccc gccgccgctg
    12721 gcgcgacgcg agaccggagg cgcgatccgc ggccggatcc ttccccgcgc actggtgcca
    12781 cggcaccgcc ggcatcgcga tggcacgcgc ggacgcggcc gcgacgctcg accggccgga
    12841 cctcctcgag ctcgccctcg tcggcgcgcg cgagacggcg tcggacgcgc tcccctccga
    12901 cgactccctg tgccacggga ccctcggcaa cctcatcgcc gtgcgcggcg cgacccgacg
    12961 caccggcgtc gacaccgggc tcgcggagtt ccgcgaccgc gcgctgcagc gcgtcctccg
    13021 cgcgggcccg cgcagcggtc tgcccgaagg ggtgaccagc gtgcgggggc tcatgctcgg
    13081 aacgtccggc gcgctctacg cgctgtgccg ggaactggag ccggggatcc cggacgcgct
    13141 gctgctggag gggccgcgct gacggtcgcc ccggttgttc gcgaggggtg gcccgggcag
    13201 ccgtcgtggg gccgcccggg ggtcggtcac atcgggtacc agcggttgcg ctgaccgtcg
    13261 gcgtccgggc cgcatcggta gctcttgccc gtgtcggact tctcgacgct gccgacctcg
    13321 gtcttcttgc agaaggcacc gggcgtgatc gtccggcccg gggcgggggc gggagccggg
    13381 gcaggagccg gggcggcagg agccggtgcg ggggcaggcg cgacgggcgc cggagcggga
    13441 gccgccggct gcggcgcggg cgccaccgtc ggcgcgaccg tgggctcggg cgtcggcgtc
    13501 ggcgcgggcg ccagcagcgt gagcgtcacg gtggatccgg cgtcggtgcg cgaccccgcg
    13561 accgggctct gggacttcac cgtcatgccg tcggtgacgc tggtcgcctc gcccgactcg
    13621 agcacgtact gcacgacgta gccggcctcg cggaggagcg tccgggcgtc ggtggcggtc
    13681 ttcgcgttga cgtcctcgac gacgtggacc acgggggtcg gcgtcgcggt gggtgtcggg
    13741 gtggggctgg gcgacgcact cgcggtggcg gccaacgcgg gggccggagc ggaccccgat
    13801 gcgccggccg gtagcgccga gccgatgatg agcagcagga ccgcgccgac cgcggtcgcg
    13861 gtgccgcgcg gacgcgaggt cagagccggg acgaaccctc ggcgcccgaa gacgaccgtg
    13921 tacagggccg ccgcgagggc gacgaggccg acggacacga acatgccgcg gaagccgcca
    13981 cccgccgcac tgatgaggat cacgagcgcg gccacggacg cgacgatcca cgtcgccgcc
    14041 gggtggatgc cgggacgcgt gtctgcgagc aacggagccg gagccggagc cgccggagcg
    14101 accggcgccg cgatggccgc ctgtcgcggc ggcaccggca tcgcgacggt cgccgcggcc
    14161 gcccgggcgc tcttgtcccg cgccgccgcc tcgcgctccg cagccttcgc gtgcatggcc
    14221 gcctcgcgct gcgcgagctt cgcggcgcgc tgctgctcgc cctccgcggc gcgcacggcc
    14281 ttagcctgcg cggcttcggc ggcccgcatc gccttgtcgt gcgctgcctc ggccgcctgc
    14341 gcgttgtgca cggcgtcgac ctgctgcgac gcggcgaggg ccgccgttgc cgctgcgctc
    14401 agagcgggcg caggcgctgc cggagcctgc accatcggcg cgacgtgctg cgtccacgtg
    14461 gcgccgtccc agtagcggag ctgcccggat ccgtcgggga accagccggc aggagcggca
    14521 gaggggacgt cgggcatgga gctcctcggg tgtgtgccgc ggcgaagggg taggcggcag
    14581 gtggtgccgt cgagtgacga cgcctgaggc tatgggcgcg ctctcctgcc cgtaagccct
    14641 cgcatggggg gtgaatagag agccgtggcg atgacgaaga ggcccctcaa aacgaacatt
    14701 tcgccaaagc cggggacggc agtggtacta agcacggccc gcacgactat gaacgcggcg
    14761 acgcacgtcg ccgtcgggtg gcggcgcgga tgagtgcggg tgaccaccga ggccaggagg
    14821 ccggagcgac cgcagccgag atcgcgtgcg atcgcggcgg caagaatatc gcgccgttgc
    14881 cgccgctcgg atgcttttgc ctggggccgc tgcctcgcgc tccgcggcct tcacttgcgt
    14941 ggccgcctct tgctgcgcga gcgtcgcggt gcgctgctgc tccccctccg cggcgcacac
    15001 ggtctttgcc tatgcagccg cgacagccgg cgtcgccttg tcttgcggta cttcaacgcc
    15061 gtcagtccaa atacttgaac gttgcttgcc actccgtacc gaaccgatct aggctttcta
    15121 catcgtcgat gagagttcga aggtttttcc agaactggat acgaacggca cgtgactctt
    15181 gtccgtgaag catcgcgatt cgtcgctcaa cctcgtccac cccgcctggc ttcttcgccc
    15241 ccgggctcag ccggtctccg taaggatgat cagtctctgg cagtatccga tcgagcggta
    15301 tcagcttcaa tgtctctgtt gaggacatcg tagccggggg aacagaaaaa tagcatccga
    15361 ggcgtatagc ttcctcggtg agctcaggag atccggtcca ccaatgaaga acgacccctt
    15421 tgacaggcgt acgatgaagc tcgcgtaaga catggaagtg cgcgccgtag ctgtggacgc
    15481 ttacaaaacg aggttgaatc tgtagctctt cgagaaccat ccgaaaaacg cgaatctgat
    15541 ctggaagggg aacacgactc gatccgtcga tccccacctc accaacgaaa gcagctaggg
    15601 agacatgtgc gctgaatgtc ttggcgtcga atgctttatt agctcgcacc agtccagggt
    15661 gaacacccac cccccagacg gctcgaaggt cacggcgagt cgatacatgg gcaaactcgt
    15721 ctaaggaacg ggttactgcg aacacgaaag caccaagact tcgtatactt tgaaccttta
    15781 gttcaggcga taggtgcgcg tgcgtgtcga ggggtggcgg tgtcctcata aagctagctg
    15841 tctcagctct tcacgtccac gttcaaccag cgactcaact cttgccaggg ggatgtcgga
    15901 cgggatttgc agatgtgcca attgagccac gctaaaagac tccgagagaa agtcccgcat
    15961 tgcaggtaca acggattttg tagcaaccca gttttgctgc ccgtcatcct tcggtagaaa
    16021 gtattggctc ccgtcattga gcccactcgc ggtaaacgaa gctcgtcgaa gcacgcagcc
    16081 aaaacagacc ccgcaggcga cattaggggc agttccatat gtgcgagcgc cagtatgaga
    16141 gcaggatgag gtcaaagtca aataggtgct cgcctcgtca actccgaccg cgtctgctac
    16201 tttagagaac atctcgccct tcgttaagtc ggcgtaagga ttgtgaacgt cataatgtgc
    16261 gccgacggct tttaggattc gcctcagtcc agctaaaaac ttcggatgtg ttgtcttagt
    16321 cgaaagactg ccgcggcggc tcttcgagag tggcggattg attgaagcat atccgttttc
    16381 cggcagccac agtggaagtt cgtcgaccga ggcgatcgca agtccaagtg ctatgaaaag
    16441 aaacgatcgc gagcgtgtcg aattctcgcg tccgtatgca gtgccgtcag gtgcgtgctt
    16501 gccgcgggcg atatttacct tgacatggtc agctttcgcg ccgggagcca atcgctcgat
    16561 ttcgtttgcg acacgcgtct gaagcggtga caggttagta gaggaccagt gcgagacgag
    16621 aatatgcttt tgactcagcg gaaccagttc gagggctgat agtaacgctc ctgtcgcgga
    16681 gtcagcaccg ccactaagta atacaacgcg ttgcgcgtcg atacctaagc gaccgatctg
    16741 ctcggcagct cctcgttctc gtagaaaggt gagagaccac gcatctcctg taaggaatcc
    16801 gagtagctgt tctaaatcct tttttactgt gtcccaaggc tttacggcga gaacgtcgat
    16861 cgtcaacgat atctctcgtt ggttccagcg cgaaaggcta ccggagcgac tggctgacct
    16921 atccgcagcg agcaccgccg ctgcgatgcg cacaagatcg atgttacgga tctttactgg
    16981 tccatactcc gcgagttgag gacccacgtt cgcgtggaag taaggcatgc tgcgcttgct
    17041 gtgccagaaa aacgtattgg caacatcagc cggaaacggc tctacaggcg gaagaactga
    17101 caggcggtac tcgaacatag ctaaccgtta tcctttgcat gagtgcgacg tagccatttc
    17161 agccctcttt caatggcctt gtctatctcc gcctgacttg cacccgtctg cgaaagattc
    17221 gatccagccg cgagatgttg actcgtctcg tagacgccgt cgacaaactc ctcgcgggac
    17281 gttccttcga tcgacgtaaa ctcgccggcc tcagaaagaa aaatttccgc aacaatgaga
    17341 ccaatcgcgt gctcagccgt cgctacagca tcagggggcg tcgggttgat ttcggtgtcg
    17401 agcatccagt ccaaaaggtg cgcggcgatc tcgcgttgtt cttccgcagg aatgtcactt
    17461 cccatgtccg catcgcagac catatcgaga attgcgcgaa caagctcaga tctagacggt
    17521 agagaagaca gccagtcgaa atccaagcca gctcttgcca gagcctctcg gtctccctct
    17581 cggaaagccc tagcgagacc agcggcacga ctagctgttg aagcgtaggt ccgcgcatta
    17641 cgccgaggag aactttgctt cttatgtccc tcacctcgct gcccgccagc gccaccgcca
    17701 ccgccaccgc caccgccacc gccaccagat cctgcacctg cacctgcacc tgcacctgca
    17761 cgggggaaag ttggaatatt taacgcttgg gcgacgacgc tctctggcaa agaagtcttg
    17821 ccgtcacttt tctgtgactc ggaccactgg tgaacaccgt cgcgaaggcc agttgacacc
    17881 ttgctagtag agcccttata ggacgagcta gtacccacaa ctatacgtcc tctttgactg
    17941 cactcaaagc attagtgagt tcggacctac cgctcgccac ggccatagcg tcaaattggc
    18001 tcagtatggc aggcgcgtca gtcaccttca gcgtcgtgag cgaagcaact ttcaactcag
    18061 aaggcttgat tctccggagt gcattgacaa cagaatcgac tgcttgcggt tgaactcgcg
    18121 agactcggag catcgcgata ataccgctgg cttgacgttg cggttcatcc acggtcacac
    18181 cgcccatata agacacaaga cttctggcgt cagatacctg aagctttatg agcatctcgt
    18241 cggtcacgcg acgggcttcg cccggtgacc gagagagaag ctgggtcgcc atgtcgcgga
    18301 ttgactccgg gagagcatcg gactcgacga agaggttctt aaaactcgcc gcaaacacca
    18361 gatatggagc aatgtctttc ttcgcgagag ccggcgacag ccgcgcccac ctgatgagac
    18421 cgtcactaaa gggcggcttt ttctcaggcg ttccgaccgc agtcgttgac ctactggtgg
    18481 catcagcctt cggcgctggg ggcgctttga tagccggagc atcatcggtg acttcgctcg
    18541 gatcgggctg atccgtggcc tccggcgtcc ccgcgaacgc ctcgagggct tcgagattcg
    18601 tacgcagtgt tcgctctcgc aaccaatcag tgagtgtctt gaaggcgtca ggaaagtact
    18661 gctcaagcac catgagcttc gcgattgtcg cttcatcaag ggcaatgcca cgcttagctg
    18721 ctatcgagag tcgcaccgac aggtcgttga ggaaccgctt aattcgacgc gggtttccgc
    18781 gcgtcttctc atgaataatt ggccgaatcc gggcggcgtt gttgcgctgc tcggcaaagt
    18841 cagcccgctg tagcgacccc acagtctcca gggagacagc gttccgtcgc gcgtcggcaa
    18901 cttcgcccac gattccctcg tactcatcat tagtcgcgac gagtgactgc acttgcagaa
    18961 ggacgaggta agcctcagta tcaaaatcgc tgagcgccgg cacaggtacg gatgtctgaa
    19021 caatcttgtg aaggtagaga cgtgccgggc tctcttcgcc attattgctg tccgatgacg
    19081 ggtacctggt tgcaatcgcg tctgctacgc gtgcctcgtc ggccgcaata acaaaggaca
    19141 tcttcggcac cgacaggaac aaacgaatag tctctagcgt ctctacaacg gtgtcgggca
    19201 agcagcggtc aaggtcatcg acaagaacga cgacgttctc aatagaggaa agcccctccg
    19261 actcaagcag gttcttaaac tccgctcgga actgcaccat gtccgtaatc ggctcgggtt
    19321 gttcctcgcc ttcgacatcg ttccttggct ttacgaggtc caggacgctg gagagggagg
    19381 gtagggacac ggtgatggcc gacgtggctg caagcttcat cgccttagtc cagtcgaccc
    19441 gcctcaatag gcgcgttaga attgcctttg acttctcccc aacaccatcg tcgggaagtg
    19501 cctgttcgat cgaagtcagg atctcgccta ttagcgattc tttgattcca agctgtgggt
    19561 cgtagcgcca cgggtccgtc tcgattacaa gacacgtcgg cttggcccct tcgggcgtgc
    19621 gtagctggcg gcctatgagt cgaagaactg atgtctttcc actcccccag gcaccggaga
    19681 gaccaagagc gatcgggtcg aggcggggat caagaacagc atccacgaca gtcgacgcaa
    19741 cagcatcgaa ggacagcagg tcgacgtcag ttggctcatc aaggaacagc ggatgactag
    19801 ctttactcac gatgccctca cttcatgcgg ccccatcaat acgtctccct ttaagtgaat
    19861 gttatgtggt gggtccatcg cacaccatgc ctgggcctcc aatgccaggt caacaaccaa
    19921 ctgtcgcgtc atcgcgtgat aggggaagca ggagacgtag acgagcccgg cgctggagcc
    19981 gccgaagagg cgaattaagc tactgtgagt ctctttgaga atggtgaggc ccgcatacca
    20041 gaactggcgc agtgcctgcc gacggtcggt ctcgcgggtg ttttcagcaa tcgggaagca
    20101 aagctgcgcg caaatccagt catggctctc gcggtcatcg agtctcgggt tcttagcctc
    20161 cgcccagcat gtggcttcca gcatgatgct cctccggtgt gcgccgcggc gaaggggtag
    20221 gcggcagatg gtgccgtcga gtgacgacgc ttgagggtat gggtgtgctc ccccgtccgt
    20281 aagccctcgc atgggggtaa agctgaacgg cgtgtgcgtc gatgcaccat acggaggccc
    20341 gtcctgccca tccagttctc tcgacgccgt tgatcgggac cgaacgaccg cggcgatgat
    20401 gtgttcgact gtatcctgcg ccggctcgtg ctcccggtac cggaggacgg tccgccggag
    20461 accgtggagg ttggcggtcg cccttacgta acgctcgacg ttccgcgcga gcttcacgat
    20521 ccggtactcg gcgttcgccc tcgaggatgc agatgagccg ggcagctgcg tcagaagcag
    20581 ctgtcgatga agatggcaat gcgtttgcac ggaacacgag ggccgagcgg ttccgcgatt
    20641 tctacaccac cctcaggtcg acccggtagc ggagaccgtg ggcgtgaagg agtctccgca
    20701 cgagcagctc gggcgttgtg tcccatcgtt tgtcagcgcg ctggatgctg cccactgcgg
    20761 tagacgaggc ccagaccatg gccggagacg accatgcacg acctatatct atcctaaaat
    20821 gacgaatgcc ccggccggac ccataggtcc ttccgaggca tgtccgtcgg gctgacagga
    20881 tttgaacctg cgaccccttg acccccagtc aagtgcgcta ccaagctgcg ccacagcccg
    20941 ctgtcccatc gctgggcaac tcgtagagcc taccgcatcg gcggcactgc tccggcacgc
    21001 acgaggcctc gggtcaggct ggcgcaccac ccgggcgacc cggagcggag gggtcaggcg
    21061 cagcggaagc agccaccctc cccggcttcg ggaacgcgtc ccgcatgtgg tcgctccgca
    21121 ggatgtcggc caccccgatg agcagcagcg agaagacgat ctgctcgatg accatccaga
    21181 gcgggtagag gcccgggatc gcggcgacca ccagggtcac gatggggaag atctggctga
    21241 agaggcgcag gcgcgagtac gcccaccagt agccggccga ggcgcgccag gcgaagtagt
    21301 agagcgtgat ggtcatcgcg agcaccacga aggagcggaa ccagacggcg ggggcgacgg
    21361 cgatgccgtc ggaggcgagg gtcagggcga tggccacggc ggtcgcgccg acggcggtct
    21421 cggcgatgag gatccaccgg atccagcgga acgcccgcgt cgtccacggg tggtcgcgca
    21481 tgtcctcggc gatgatgtgg cccgcctggc gcccggcggc gatccgatcg aggcggctga
    21541 gcagctggtc caccggtgcg atcctccgtg tctcgtgagc gggcgtcgga tgcgcccgga
    21601 tcagggtacg acgtgacgcc tggagccgcc cgcgaacgtg gggagcggcg cgatccggac
    21661 aggcgacgcg ggcaccagcc ggcggtcggc ggatcccccg catgacggcc cgtgacgccc
    21721 cgcgtcgtca cgcggggaca cccgccgtca cacccctcgc caccccgcgc gacccgcccc
    21781 taccgttgcc ccaccgcgag gcgcggcacc ggtcgcgccc cttcacgaga ggacaggaca
    21841 tgaccctgat cgaccgcgag ccccgacccg catccggctc ccccacgccc gcccacggca
    21901 ccgcgaacgc ggacgcaccc gcgaggaccg accgcccgcg ccccgctccc ctcggcgccg
    21961 cccccgtcga ccgctggaag ggcgcaccgc gtcccacgac gcccgccgcg tggatcgccc
    22021 gcgcccgcga ggtcgccgac atcctcgccg tcgaccaggt cgagcgcgac cgcgccggcg
    22081 ccagcccgca ccaggaggtc gcgctcctca agcacgccgg cctcgtcacg ctgctcgggc
    22141 ccgcggagca cggcggcggc gggcagacct gggacaccgc gtacaaggtg atccgcgcgg
    22201 tcgcccgcgg cgacggatcc atcggccagc tcctcgggta ccactacctc tgggcgtggg
    22261 ccgcgcggct cgtcggcacg gacgcgcaga tcgaggccgt ggagaagctc gccacgacag
    22321 gcaacctgct cttcggcggc gccgtgaacc cgcgcgactc cgacctcgtc atccgcgagg
    22381 acggcgacga cctgatcttc tccggccgga agtcgttcag cacgggcggc gtcgtgtccg
    22441 acctcaccgt gctcgagggc gtcatcgagg gcacggagac ccacgtgttc gcgatcgtgc
    22501 cgacggacca gcccggcatc gtcttcggcc acgactggga cagcctcggg cagcggctca
    22561 cggagtccgg ctcggtcgag atccgcgacg tgcgcgtgcc gtggacggat gccgccggct
    22621 tcgtcgacaa ggtgttccag ccgctcgtct acggcacgct caacgtgccg gcgatccagc
    22681 tcgtgttcgc gaacttctac cagggcatcg cggagggcgc gctcgagacg gccgccgcgt
    22741 acacgcgcag caccacgcgc gcatggccgt acggcggcga cgacaaggag cgcgcgaccg
    22801 acgagtggta cgtgctcgag ggctacgggc agctgcagtc gaaggtgtgg gcgtcggagg
    22861 cgctgctcga tcgggtgggc gccgagatca gcgccgtgct gcacgcgccg cgcgagaagc
    22921 tcacggagcg gaagcgcggc gagatcgccg tgcgcgtcgc ggcggccaag gcgcgcatcg
    22981 cggaggacgg gctggaggtc ggcacgcgga tcctcgagct cacgggcgcg cgcgcctcct
    23041 cctcgaaggc cgggctcgac atcttctgga ggaacctgcg gacgcacacg ctgcacgacc
    23101 cgatccccta caagcgccgc gaggtcggcc ggcacgtgct gctcggcgag atcccggagc
    23161 cg
//
