LOCUS       NZ_CP094676            21029 bp    DNA     linear   CON 30-MAY-2024
DEFINITION  Streptomyces sp. CB09030 chromosome, complete genome.
ACCESSION   NZ_CP094676
VERSION     NZ_CP094676.1
KEYWORDS    RefSeq.
SOURCE      Streptomyces sp. CB09030
  ORGANISM  Streptomyces sp. CB09030
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1  (bases 1 to 8368456)
  AUTHORS   Shi,J. and Huang,Y.
  TITLE     Genomic of Streptomyces sp. CB09030
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 8368456)
  AUTHORS   Shi,J. and Huang,Y.
  TITLE     Direct Submission
  JOURNAL   Submitted (10-FEB-2022) Xiangya International Academy of
            Translational Medicine, Central South University, Changsha, Hunan
            410013, China
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: 2021
            Assembly Method                   :: Canu v. v1.5; Racon v. v3.4.3
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 1510.0x
            Sequencing Technology             :: Oxford Nanopore
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_022827705.1-RS_2024_05_30
            Annotation Date                   :: 05/30/2024 05:11:20
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 7,205
            CDSs (total)                      :: 7,118
            Genes (coding)                    :: 7,015
            CDSs (with protein)               :: 7,015
            Genes (RNA)                       :: 87
            rRNAs                             :: 6, 6, 6 (5S, 16S, 23S)
            complete rRNAs                    :: 6, 6, 6 (5S, 16S, 23S)
            tRNAs                             :: 66
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 103
            CDSs (without protein)            :: 103
            Pseudo Genes (ambiguous residues) :: 0 of 103
            Pseudo Genes (frameshifted)       :: 40 of 103
            Pseudo Genes (incomplete)         :: 75 of 103
            Pseudo Genes (internal stop)      :: 10 of 103
            Pseudo Genes (multiple problems)  :: 21 of 103
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 20:41:32
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 3784508
            Orig. end                         :: 3805537
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP094676.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..21029
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene"
                     /region_number="21"
                     /rules="(PT_phytoene_like or phytoene_synt or Lycopene_cycl
                     or Lycopene_cycl_fung or T1TS or T1TS_KS or T2TS or TS_UbiA
                     or TS_Pyr4)"
                     /tool="antismash"
     cand_cluster    1..21029
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /kind="single"
                     /product="terpene"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..21029
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:11029](-)"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..11029)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
     gene            complement(657..1913)
                     /locus_tag="L6J92_RS16215"
                     /old_locus_tag="L6J92_16215"
     CDS             complement(657..1913)
                     /GO_function="GO:0004553 - hydrolase activity, hydrolyzing
                     O-glycosyl compounds [Evidence IEA]"
                     /GO_process="GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016325253.1"
                     /locus_tag="L6J92_RS16215"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="L6J92_16215"
                     /product="glycoside hydrolase family 16 protein"
                     /protein_id="WP_243781461.1"
                     /transl_table=11
                     /translation="MVRPSLLRRCLLAAALSAGLAASLVTGPAQAEPEGPATAGTAGAS
                     AAAVVFSDTFDGPAGAAVDSSKWQIETGDNVNNHERQYYTSGNKNAALDGQGHLVVTAR
                     KENPANYQCWYGTCQYTSARLNTSGKFTAQYGHVEARMKVPRGQGMWPAFWMLGTPVNW
                     PDSGEIDIMENVGFEPSTVHGTLHGPGYSGSGGIGAGYTLPGGQSFADAFHTFAVDWAP
                     DSVTWSVDGNVYQRRTPADLGGRQWVFNRPYFLILNLAVGGYWPGDPDGSTVFPQTLVV
                     DHVSVTTGDSPAGGAIRGLAGKCVDVAAADTANGTPVQLYDCNGTTAQQWTVGSDGTIR
                     ALGKCLDVNAGGTADGTVVQLWDCNGSAAQQWVVTAARDIVNPQADKCLDVTGNNSANG
                     TRLQIWTCAGTANQKWTVG"
     misc_feature    complement(1983..1996)
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 13.1"
                     /tool="antismash"
     misc_feature    1984..1997
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 13.12"
                     /tool="antismash"
     misc_feature    complement(1985..1998)
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 13.04"
                     /tool="antismash"
     misc_feature    complement(1986..1999)
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 14.32"
                     /tool="antismash"
     misc_feature    1986..2000
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence: weak,
                     score: 15.82"
                     /tool="antismash"
     misc_feature    2021..2036
                     /note="TFBS match to DasR, N-acetylglucosamine dependent
                     repressor, confidence: weak, score: 19.73"
                     /tool="antismash"
     gene            complement(2047..2586)
                     /locus_tag="L6J92_RS16220"
                     /old_locus_tag="L6J92_16220"
     CDS             complement(2047..2586)
                     /GO_component="GO:0005576 - extracellular region [Evidence
                     IEA]"
                     /GO_process="GO:0046677 - response to antibiotic [Evidence
                     IEA]"
                     /GO_process="GO:0071555 - cell wall organization [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007389368.1"
                     /locus_tag="L6J92_RS16220"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="L6J92_16220"
                     /product="VanZ family protein"
                     /protein_id="WP_195887354.1"
                     /transl_table=11
                     /translation="MARAVSGLRLWPRPRAAEARKADPPERHALALPLRLLATACAFVF
                     MVAFAVVLARLTLHPSPASEALTHTNMRPGSSLRAYLDQPALRDAVKQIGGNILLGVPF
                     GVLVPVVAPRTRGVLRVLLLTAVVMLLVEFAQGALVTGRAFDVDDVILNTSGALIGYLL
                     LGRRMSRTVHARKARG"
     gene            complement(2725..3408)
                     /locus_tag="L6J92_RS16225"
                     /old_locus_tag="L6J92_16225"
     CDS             complement(2725..3408)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016430779.1"
                     /locus_tag="L6J92_RS16225"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="L6J92_16225"
                     /product="DUF4230 domain-containing protein"
                     /protein_id="WP_224291507.1"
                     /transl_table=11
                     /translation="MTTPVKKPTSDDRKPAPRMPGWAKALTAVVLVLAVLFAGLRLSVL
                     PGLKDLFGSETQDRSGPALLKSIQDMSRYDAASGNFQVVVDLEKDTKFLPDAIRGTRTL
                     YVGAGTVDAYVDLGKLGEDDVQVDGDRTSATLRLPHAALGEPALDPDRSYAVSKQRGLL
                     DRLGDLFSDNPNGEQAVQKLASRHIGEAAKDSELKTRAESNTTAMLQGLLRSLGFEDVR
                     VAYKG"
     gene            complement(3676..4062)
                     /locus_tag="L6J92_RS16230"
                     /old_locus_tag="L6J92_16230"
     CDS             complement(3676..4062)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019327710.1"
                     /locus_tag="L6J92_RS16230"
                     /note="This anti-anti-sigma factor, or anti-sigma factor
                     antagonist, belongs to a family that includes characterized
                     members SpoIIAA, RsbV, RsfA, and RsfB; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /old_locus_tag="L6J92_16230"
                     /product="anti-sigma factor antagonist"
                     /protein_id="WP_243781462.1"
                     /transl_table=11
                     /translation="MRQESPSPTRHLRVRHERGHAVLEFRGEIDIASATEIAPHLDRET
                     RRPGARVVLDLGGIEFFDCSGLRLLARARNQVLAGGGEVHLVCSHPLTLRMLRITGLTR
                     LLPPRPTLREVLGPALPTARRTGY"
     misc_feature    4126..4140
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence: weak,
                     score: 15.5"
                     /tool="antismash"
     misc_feature    complement(4128..4144)
                     /note="TFBS match to HexR, Glucose-responsive regulator,
                     confidence: weak, score: 15.67"
                     /tool="antismash"
     gene            complement(4217..5158)
                     /locus_tag="L6J92_RS16235"
                     /old_locus_tag="L6J92_16235"
     CDS             complement(4217..5158)
                     /EC_number="1.-.-.-"
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /NRPS_PKS="Domain: PKS_ER (21-310). E-value: 1.3e-56.
                     Score: 184.0. Matches aSDomain:
                     nrpspksdomains_L6J92_RS16235_PKS_ER.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ADH_N"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ADH_zinc_N"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1028: crotonyl-CoA reductase / alcohol dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003978080.1"
                     /locus_tag="L6J92_RS16235"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="L6J92_16235"
                     /product="NADP-dependent oxidoreductase"
                     /protein_id="WP_243781463.1"
                     /sec_met_domain="ADH_N (E-value: 1.2e-09, bitscore: 36.8,
                     seeds: 66, tool: rule-based-clusters)"
                     /sec_met_domain="ADH_zinc_N (E-value: 6.9e-19, bitscore:
                     66.8, seeds: 86, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTTMRAVSQDVLGGPEVLKEVRVERPVPRPNEVLVRVRAAGVNPT
                     DWKHRADGGFLGEPPFVLGWDVSGTVESVGIGVAAFRPGDEVFGMLSYPFGHGSHAEYV
                     TAPARTFTHLPAGTDHVRAGALPLVSLTAWQALVERAGLQPGQRVLIHAAAGGVGHVAV
                     QIAKARGAHVIGTASAGKHAFLRSLGADEAVDYRETDFTEAVRDVDVVLDTIGGDTSLR
                     SLRVLRPGGVVVSILPVGSGEFFEEAGRLGVRAVRMLVDADRADMREIARLVEAGKLEP
                     TIAKTFPLAEAAGAHALGETGRTTGKIVLVVD"
     aSDomain        complement(4229..5095)
                     /ASF="ER configuration inconclusive"
                     /aSDomain="PKS_ER"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_L6J92_RS16235_PKS_ER.1"
                     /evalue="1.30E-56"
                     /label="L6J92_RS16235_PKS_ER.1"
                     /locus_tag="L6J92_RS16235"
                     /protein_end="310"
                     /protein_start="21"
                     /score="184.0"
                     /tool="antismash"
                     /translation="RVERPVPRPNEVLVRVRAAGVNPTDWKHRADGGFLGEPPFVLGWD
                     VSGTVESVGIGVAAFRPGDEVFGMLSYPFGHGSHAEYVTAPARTFTHLPAGTDHVRAGA
                     LPLVSLTAWQALVERAGLQPGQRVLIHAAAGGVGHVAVQIAKARGAHVIGTASAGKHAF
                     LRSLGADEAVDYRETDFTEAVRDVDVVLDTIGGDTSLRSLRVLRPGGVVVSILPVGSGE
                     FFEEAGRLGVRAVRMLVDADRADMREIARLVEAGKLEPTIAKTFPLAEAAGAHALGETG
                     RTTGKIVL"
     CDS_motif       complement(4661..4723)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_L6J92_RS16235_0001"
                     /evalue="1.70E-08"
                     /label="PKSI-ER_m5"
                     /locus_tag="L6J92_RS16235"
                     /protein_end="166"
                     /protein_start="145"
                     /score="26.8"
                     /tool="antismash"
                     /translation="GQRVLIHAAAGGVGHVAVQIA"
     misc_feature    5396..5410
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: weak, score: 17.06"
                     /tool="antismash"
     misc_feature    5402..5411
                     /note="TFBS match to ToxT, Regulator of MSHA biosynthesis,
                     confidence: weak, score: 14.18"
                     /tool="antismash"
     gene            5562..7325
                     /locus_tag="L6J92_RS16240"
                     /old_locus_tag="L6J92_16240"
     CDS             5562..7325
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019327712.1"
                     /locus_tag="L6J92_RS16240"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="L6J92_16240"
                     /product="ATP-binding protein"
                     /protein_id="WP_195887358.1"
                     /transl_table=11
                     /translation="MELATPPPAARVPVAWHSWWLMPLGLGGGTVAATFMSSERITVAV
                     AGAAATVAGTVCVRLLLRTRAQLGRAENAHRSARSENSQQWQQHVAGLERKFSAERSDL
                     DAQLTEQAQTYEERLAEHTRAYEDRLAEQATSYEARFAERTEAWQEQLGHQLAAVSRLA
                     DEQLPDAMRRLRSGDAIDDILPTVEQCSKVGADLQAELRKVLRTALIGVEAEFDRSTSA
                     EQAVISVGNRIHVLTSKLRGRLHEMQGEHGRLPTVARGLMELDQAIGPADCLAASIGVL
                     GGSDRPGRQWQEPQRLLSVMRGGIGRIKDFHRVQLRHLPELGVDGGLVDHLTLIFAHLL
                     DNAARYSPPTEPVVVSGKEVPNGVGIEIQDSGKGLSDEKKREAEHALAGTSPGAGLGGI
                     SEDANIGLRVVGALARRYGIRVTFADSPWLGTSVVVVVPHKYFSPLPSAAAPATVPDTA
                     QAATAPAADLVPPAVVEAAAAPAPAVESTRAADPAPAADTAVETTPGGLPRRRSRRAEP
                     AAASGAAAPAAQQPGSEAADRAQASAVPPDASFTGLAAFATAGRDPGAGVGTSESTTGG
                     ASTEHRTEESD"
     gene            7331..7741
                     /locus_tag="L6J92_RS16245"
                     /old_locus_tag="L6J92_16245"
     CDS             7331..7741
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019057749.1"
                     /locus_tag="L6J92_RS16245"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="L6J92_16245"
                     /product="roadblock/LC7 domain-containing protein"
                     /protein_id="WP_031031941.1"
                     /transl_table=11
                     /translation="MTHQGTDVSWALRDLVESIQEIRFALVASSDGKAITSYGAEDPDD
                     VDRFAAVVAGLQALAQPVAEQFPQHAGQLRLAMIEVDGGHLFVVRAGMETYLGVLAREG
                     LDQGLLGHQMRDLARRMGELLGTTPRQEEHSG"
     gene            7738..8109
                     /locus_tag="L6J92_RS16250"
                     /old_locus_tag="L6J92_16250"
     CDS             7738..8109
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003995719.1"
                     /locus_tag="L6J92_RS16250"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="L6J92_16250"
                     /product="DUF742 domain-containing protein"
                     /protein_id="WP_031031940.1"
                     /transl_table=11
                     /translation="MSAPRRPTDPSGLERYYVLTGGRSGPGGSASTLDVATLVVARAAP
                     LPGMQHEHEEILRRCRDPLSVAELGAHLHLPFNILAVLLSDLLQAGSVEARDPIPALDA
                     GRGPDLALLEEVLSGLQRL"
     misc_feature    7873..7875
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            8090..8695
                     /locus_tag="L6J92_RS16255"
                     /old_locus_tag="L6J92_16255"
     CDS             8090..8695
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014156547.1"
                     /locus_tag="L6J92_RS16255"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="L6J92_16255"
                     /product="ATP/GTP-binding protein"
                     /protein_id="WP_031031937.1"
                     /transl_table=11
                     /translation="MDFKGFDRPGSSTAGDTRSVKVMIAGGFGTGKTTMVRAVSDIKPL
                     TTEETLTQASADVDPLIGVADKTQTTVSLDFGKIGLNETLMLYLFGTPGQERFWFLWNG
                     LFKGALGAVVLVDTRRLASSFRAIEEMERQKVPFVIALNVFPDSRDYPVDEIRDALDIA
                     PHTPVVAFDARDPTAGRDVLVTLIRHLKDRSAAALEPR"
     gene            8692..9939
                     /locus_tag="L6J92_RS16260"
                     /old_locus_tag="L6J92_16260"
     CDS             8692..9939
                     /GO_function="GO:0004497 - monooxygenase activity [Evidence
                     IEA]"
                     /GO_function="GO:0005506 - iron ion binding [Evidence IEA]"
                     /GO_function="GO:0016705 - oxidoreductase activity, acting
                     on paired donors, with incorporation or reduction of
                     molecular oxygen [Evidence IEA]"
                     /GO_function="GO:0020037 - heme binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) p450"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1007: cytochrome P450"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019327716.1"
                     /locus_tag="L6J92_RS16260"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="L6J92_16260"
                     /product="cytochrome P450"
                     /protein_id="WP_243781464.1"
                     /sec_met_domain="p450 (E-value: 1.2e-06, bitscore: 26.2,
                     seeds: 50, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNDDQTPSAPTGGGCPVAHGEGAVRLYGPDAATDPHKIYARLRGE
                     HGAVAPVLLEDDVPAWLVLGYRENRRVLDNPLQFSRDSRIWRDFQDGRVAETAPLMQMV
                     GWRPDCVSQDGEPHRRLRGAVTDNLYAVAGRGIRRHITHFANKQIDAFADEGRADLVAD
                     FAEYLPMLVLTRVFGLAEREGRTLAESSNQVIKGGADALTHNERIMGILGELAERKRRE
                     PGSDFASGLIEHNSGLDEDEIVNHLRLVLITAHTTTSNLLARVLQLVLTDSARLSGLVS
                     GQLNMSAVVEEVMWNSPPLAVLPGRFATADLELGGCPVKEGDLLVLGLTAGNHDPEIRP
                     DTGVSVEGNASHLAFSAGPHECPGQNIGQAIIETAVDVLLHRLPGLRLAVPASELTSTA
                     STWESRLDSLPVEFAR"
     gene            complement(10001..11029)
                     /locus_tag="L6J92_RS16265"
                     /old_locus_tag="L6J92_16265"
     CDS             complement(10001..11029)
                     /EC_number="4.2.3.169"
                     /GO_function="GO:0016829 - lyase activity [Evidence IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /GO_process="GO:0016114 - terpenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: T1TS"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1052: Terpene synthase/cyclase metal-binding domain
                     protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010040594.1"
                     /locus_tag="L6J92_RS16265"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="L6J92_16265"
                     /product="7-epi-alpha-eudesmol synthase"
                     /protein_id="WP_194274495.1"
                     /sec_met_domain="T1TS (E-value: 4.7e-72, bitscore: 242.4,
                     seeds: 237, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MQDVRFDLPFDTPVSPHLAHARERHLRWVRERGLVRSAAGFEEYR
                     SWDLSEAAARTYPHASADDMVVLMNWFSLAFLFDDQFDAARPDRAERIAEVARELIATP
                     LRPAGTPPRVECPITLAWAEVWGHLSDGMSLTWKSRFAASWGRFLVAHCEEVDLAAHGR
                     AATLGIEEYAVFRRRTVGIHHSIDAGERSRGFEVPAAAMAHPLMERMRDLAADTIGFMN
                     DIHSFERERRRGDGHNLVAVLQRERGCSWQEAADEAYRMTTDCLDEYVALEARVPQMCD
                     ELGLDGDGRTRVRLGVEAIQHWINGNYEWALTTGRYAAAKDGPVATAEQAGRGSVDDLL
                     GV"
     misc_feature    complement(11215..11233)
                     /note="TFBS match to LexA_variant_3, Repressor of DNA
                     damage response, confidence: weak, score: 18.57"
                     /tool="antismash"
     gene            11290..11685
                     /locus_tag="L6J92_RS16270"
                     /old_locus_tag="L6J92_16270"
     CDS             11290..11685
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003978082.1"
                     /locus_tag="L6J92_RS16270"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="L6J92_16270"
                     /product="VOC family protein"
                     /protein_id="WP_194274494.1"
                     /transl_table=11
                     /translation="MALVNAGVVVLDCAEPERLAEFYKGLLGAEETDVTANRIEIEGPR
                     GFRLAFRRDVNATPPSWPRPENSLQVHLDLVVADLDEAERAIVGLGGRPVEAKDAAGPH
                     EERGFSDPAGHSFTLRLAVAPTAPKQG"
     gene            complement(11731..12033)
                     /locus_tag="L6J92_RS16275"
                     /old_locus_tag="L6J92_16275"
     CDS             complement(11731..12033)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004979470.1"
                     /locus_tag="L6J92_RS16275"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="L6J92_16275"
                     /product="DUF4235 domain-containing protein"
                     /protein_id="WP_194274493.1"
                     /transl_table=11
                     /translation="MAKTKKKKLPLAYKPVGFALGWLGGTLAGLAFQKTWKLIRDEDDA
                     PDALDPDRGWGEILLAAAIQGAIFAAVRSAVDRTGAKAIERSTGTWPIPGKGGRD"
     gene            complement(12122..13147)
                     /locus_tag="L6J92_RS16280"
                     /old_locus_tag="L6J92_16280"
     CDS             complement(12122..13147)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) GST_C"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003978084.1"
                     /locus_tag="L6J92_RS16280"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="L6J92_16280"
                     /product="glutathione S-transferase C-terminal
                     domain-containing protein"
                     /protein_id="WP_243781465.1"
                     /sec_met_domain="GST_C (E-value: 4.5e-07, bitscore: 28.7,
                     seeds: 35, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSGDDATPGNSGYGRKAFKRSRSHFADRITADGRDGWPVEPGRYR
                     LVVSRACPWASRALVSRRLLGLEDALSLAVADPVQDDRSWRFTLDPDGRDPVLGIRFLS
                     EAYDRRETGYPGGVSVPAVVDVPSGKLVTNDYQQITLDLATEWAALHRPGAPDLYPEAL
                     RAEIDEVMAGVYEDVNNGVYRAGFATGQEEYEAACTGVFRRLEQLTPRLEGQRYLVGDT
                     VTEADIRLFTTLVRFDAVYHGHFKCNRWKLAENPVLWAYVRDLFQTPGFGDTVDFDHIK
                     RHYYQVHTGINPTGIVPLGPDLAGWLAPHHREELGGRPFGDGTPPGPVRAEEEVPARGR
                     P"
     gene            13268..14263
                     /locus_tag="L6J92_RS16285"
                     /old_locus_tag="L6J92_16285"
     CDS             13268..14263
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0008324 - monoatomic cation transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0015562 - efflux transmembrane transporter
                     activity [Evidence IEA]"
                     /GO_process="GO:0006812 - monoatomic cation transport
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003978085.1"
                     /locus_tag="L6J92_RS16285"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="L6J92_16285"
                     /product="cation diffusion facilitator family transporter"
                     /protein_id="WP_224220398.1"
                     /transl_table=11
                     /translation="MSESASEQKPGRDGESRADRRTRVTVLVALAANLVIAVAKAVGGF
                     FAGSPALLSEAAHSVADSMNEIFLLAALRRSRRPADRRHPFGYGKERFFWSLLAAVGIF
                     VMGGCFSFFQGVEALRSGAEEELSGYVAGLIVLGVALLAEGASLLRALHQVRGQGGLAT
                     GLRDPALRTVVAEDGTAVLGVTLAMIGMVLHMVTGQVVWEACASLAIGALLVYVAYRLG
                     REARDQLIGEAADPEADGRIRELLRAQPEIDSVEALFTMKTGLDSALVAARVDLVPGLD
                     SEEVEEAAVRIKRSIAHTVPEAGQVFLDVTDRPAREAAQSPAATGERGGA"
     gene            complement(14336..14785)
                     /locus_tag="L6J92_RS16290"
                     /old_locus_tag="L6J92_16290"
     CDS             complement(14336..14785)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003978086.1"
                     /locus_tag="L6J92_RS16290"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="L6J92_16290"
                     /product="nitroreductase family deazaflavin-dependent
                     oxidoreductase"
                     /protein_id="WP_031031921.1"
                     /transl_table=11
                     /translation="MPLEGEYEPSPTQWVRDQVELYEGSGGTEGTTHPDTGLPVIVLTS
                     RGARSGKIRKTPLMRVEHDGRYAAVASLGGAPKHPVWYFNVLAEPHVELQDGPRKQDMT
                     AREVTGAEKAEWWERAVAAYPPYADYQKKTGREIPVFVLEPADAG"
     gene            15170..16384
                     /locus_tag="L6J92_RS16295"
                     /old_locus_tag="L6J92_16295"
     CDS             15170..16384
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) p450"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1007: cytochrome P450"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004978785.1"
                     /locus_tag="L6J92_RS16295"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="L6J92_16295"
                     /product="cytochrome P450"
                     /protein_id="WP_243781466.1"
                     /sec_met_domain="p450 (E-value: 3e-26, bitscore: 90.9,
                     seeds: 50, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTDTTTDPDTTRPVAYPQDRTCPYHPPAAYDPLRTGPPLAPVTLF
                     DGRPAWLVTGHTLARRLLVDQRLSTDRTRDGFPLTSPRLAGIRSRKLALLGVDDPEHRA
                     QRKMVLPEFTLKRAAALRPRIQEIVDERLDAMIAAGPPADLVQAFALPVPSMVICALLG
                     VPYADHEFFEEQSRRLLRGPLPADVRDARDRLESYLGELIDGKRTSPGDGLLDDLIRDR
                     LEEGEIDREQLISFAVILLIAGHETTANMISLGTYTLLENPGRLAELREDPALLPGAVE
                     ELMRMLSIADSLLRTATEDMEVEGHTIRAGDGVVFSTSVINRDGTVYPEPDAIDWHRPA
                     RHHVAFGFGIHQCLGQNLARAELEIALRTLFERLPTLRLAVPAQEIPHKPGDTIQGMLE
                     LPVAW"
     gene            16409..16609
                     /locus_tag="L6J92_RS16300"
                     /old_locus_tag="L6J92_16300"
     CDS             16409..16609
                     /GO_function="GO:0005506 - iron ion binding [Evidence IEA]"
                     /GO_function="GO:0009055 - electron transfer activity
                     [Evidence IEA]"
                     /GO_function="GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1265: ferredoxin"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011027347.1"
                     /locus_tag="L6J92_RS16300"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="L6J92_16300"
                     /product="ferredoxin"
                     /protein_id="WP_243783063.1"
                     /transl_table=11
                     /translation="MDIGIDKDVCIGAGQCAMTAPDVFTQDDDGYSTLQAGREDGGGSP
                     LVREAARACPVGAITVSERVG"
     gene            16828..17301
                     /locus_tag="L6J92_RS16305"
                     /old_locus_tag="L6J92_16305"
     CDS             16828..17301
                     /GO_function="GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Flavoprotein"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010040565.1"
                     /locus_tag="L6J92_RS16305"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="L6J92_16305"
                     /product="flavoprotein"
                     /protein_id="WP_243783064.1"
                     /sec_met_domain="Flavoprotein (E-value: 9.1e-10, bitscore:
                     37.2, seeds: 143, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MASGVGALIDAALRRDWEVGVFATPVAMDGFFDTADVEARTGRPI
                     RSAWRRPGEPRPFPAPDAVVVAPATFNTVNKWAAGLADTLAVATLCEACGLGVPVGVLP
                     CVSDALASHPAYRASLDRLRGMGVRFGDPYEGGAAGGDRRFHWERALDLLERR"
     gene            17380..18348
                     /locus_tag="L6J92_RS16310"
                     /old_locus_tag="L6J92_16310"
     CDS             17380..18348
                     /EC_number="1.1.1.-"
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1039: aldo/keto reductase family oxidoreductase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003978092.1"
                     /locus_tag="L6J92_RS16310"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="L6J92_16310"
                     /product="aldo/keto reductase"
                     /protein_id="WP_194274489.1"
                     /transl_table=11
                     /translation="MQYVKLGSTGLDVSRICLGCMTYGVPGRGAHEWTLDEDAARPLIR
                     QALEAGVTFFDTANVYSDGTSEEIVGKALRDFARRDDFVLATKVHGRMRPGPNGAGLSR
                     KAIMTEIDHSLRRLGTDHVDLYQIHRYDPHTPVEETMEALHDLVKAGKVRYLGASSMYA
                     WQFSKAQYTAERHGWTKFVSMQNHYNLVYREEEREMLPLCADQGVGVLPWSPLARGRLT
                     RDWDTATGRSATDAFGSTLYPEGDRAVVEAVTRIAGERGVPRAQVALAWLLHQDTVTAP
                     IVGASKPGHIEDAVAAVELVLGEKEIEELESPYTPHPVAGH"
     gene            complement(18398..19063)
                     /locus_tag="L6J92_RS16315"
                     /old_locus_tag="L6J92_16315"
     CDS             complement(18398..19063)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011027343.1"
                     /locus_tag="L6J92_RS16315"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="L6J92_16315"
                     /product="DUF4232 domain-containing protein"
                     /protein_id="WP_243781467.1"
                     /transl_table=11
                     /translation="MANTSQPVRRTALLASGLAVLGLLSACGSENGTSGTPPPSHSARA
                     SDAAPSAGTGTATDPGTAAAAGTPSDTAGSASASARTDGRCHTSELRAAVGRLDPGAGQ
                     RNFPLVLTNTSERTCTVYGYPGAAFVDASGKQLGPDPERAPGSPETLTLTPGASAWAGL
                     SFSSPEISGARTATPAALLVTPPDERASLKVEWTAGAVPVGGNASSVSVTALEAGTGP"
     misc_feature    20327..20341
                     /note="TFBS match to VqsM, Regulator of quorum-sensing
                     signalling systems, confidence: medium, score: 18.18"
                     /tool="antismash"
ORIGIN
        1 cgttgcggcg gtccttgttc gggctgccgg ccgcacggcc aaggaccttg tggccgccgc
       61 cgtcggggat gcggccgagc tttttgacgt cgatgtggac cagttccccg ggccgggacc
      121 gttcgtagcg gcgcacgggt tcgccggtgg cgcggtccag cgtggacagg gcgggcaggt
      181 ggtgccggac aaggatgcgg tgggcggtgg aggcggcgat gtcgcagcgg gcggccagcc
      241 gcaccggtcc gatccggtgc tcgcgccgca gtcgcaggac ctggtgctcg accggggcgg
      301 gcgtctggcg cgggctgtgg tgcgggcggc tggagcggtc gtgcatcccg gccgcgccca
      361 tctgtcggta gcggcctgcc cagcgggcgg cggtgctgtg gctgacctgg aaacgttccg
      421 cggcccgccg cagcggccag ccgtcgtcca caacacaccg ggccagacgc agcctgccgg
      481 tcggggtcag cggggcatta cggtgggaca cgagggcctc ctggcggtcg gcggtagatg
      541 tcgcaatcca caccgaaccc agaaggccct cacctgttca agcacccagc gctcgtgtca
      601 ccaacgtccc gggacagcac acctaggtcg tgtccgggcc ggccccgccc gctggctcag
      661 ccgaccgtcc acttctggtt ggcggtgccc gcgcaggtcc agatctgcag ccgggtgccg
      721 ttggccgagt tgttgccggt gacgtcgagg cacttgtcgg cctgcggatt gacgatgtcg
      781 cgcgccgcgg tgacgaccca ctgctgggcg gcgctgccgt tgcagtccca cagctggacg
      841 accgtgccgt ccgccgtgcc gccggcgttc acgtccaggc acttgccgag cgcccggatc
      901 gtgccgtcgg agcccaccgt ccactgctgg gccgtggtgc cgttgcagtc gtagagctgc
      961 acgggcgtgc cgttggcggt gtccgccgcg gcgacgtcca cgcacttgcc ggccaggccc
     1021 cggatcgcgc cccctgccgg tgagtcgccg gtcgtcaccg agacgtggtc gacgaccagg
     1081 gtctgcggga agaccgtgga gccgtccggg tcgcccggcc agtagccgcc gaccgccagg
     1141 ttcaggatca ggaagtacgg cctgttgaac acccactgcc tgccgcccag gtcggccggg
     1201 gtgcgccgct ggtagacgtt gccgtccacc gaccaggtga ccgagtcggg cgcccagtcg
     1261 acggcgaagg tgtggaaggc gtccgcgaag gactggccgc ccggcagggt gtacccggcg
     1321 ccgatgccgc cggagccgga gtagccgggg ccgtgcaggg tgccgtgcac ggtggagggc
     1381 tcgaagccga cgttctccat gatgtcgatc tcgccggagt ccggccagtt caccggggtg
     1441 cccagcatcc agaacgcggg ccacatcccc tgcccgcgcg gcaccttcat ccgcgcctcg
     1501 acgtgcccgt actgcgccgt gaacttcccc gaggtgttga gccgggcgga cgtgtactgg
     1561 caggtgccgt accagcactg gtagttggcc gggttctcct tgcgggccgt gacgaccagg
     1621 tggccctggc cgtccagggc ggcgttcttg ttgccggagg tgtagtactg ccgttcgtgg
     1681 ttgttgacgt tgtcgccggt ctcgatctgc cacttcgagg agtcgacggc cgcgccggcc
     1741 gggccgtcga aggtgtcgga gaagaccacg gcggcggccg aggcgccggc ggtcccggcg
     1801 gtcgcggggc cttcgggctc cgcctgggcg gggccggtca cgagggacgc ggcgagcccg
     1861 gcggacaggg cggcggcgag gagacatctg cggagcaggc ttgggcggac cacggctctc
     1921 ccttccgtac ggcgctccgc gggggagcgc cgaccgaggc gggggtggag tggggatgtc
     1981 gcctctttat tcaaatagtg aggtaagggg tggtcaatac attggtacgg accagaagtg
     2041 ccgtcttcag ccccgggcct tgcgtgcgtg caccgtgcgg ctcatccgcc ggccgaggag
     2101 caggtatccg atcagcgcgc cactggtgtt gaggatgacg tcgtcgacgt cgaaggcccg
     2161 cccggtgacg agcgcgccct gcgcgaactc caccagcagc atcaccacgg ccgtcagcag
     2221 caggacccgc agcaccccgc gcgtgcgcgg cgccacgacc ggcacgagca cgccgaacgg
     2281 cacgcccagc aggatgttcc cgccgatctg cttcacggcg tcccgcagtg cgggctggtc
     2341 caggtaggcc cgcagcgagc tgcccggtcg catgttggtg tgcgtcaggg cctcggaggc
     2401 gggggagggg tgcagggtca gccgcgccag caccaccgcg aacgccacca tgaagacgaa
     2461 cgcgcacgcc gtggccagca gccgcaacgg cagggcgagc gcgtgccgtt cgggcgggtc
     2521 ggccttccgc gcctctgcgg cgcgggggcg cggccacaga cgcaatcctg agacggcacg
     2581 agccatgtcg gtcctccagt cgtcaacgtc cccgcgtgga agggcggtta cccgccgcgc
     2641 cgccgaggat gcccggcagt gcgcaacggg ccgcatccgc tccgcccgcc gccacccgcg
     2701 cgccctcccg ctgcccgggg gggctcagcc cttgtacgcc acccgcacgt cctcgaagcc
     2761 cagggagcgc agcaggccct ggagcatcgc cgtggtgttg ctctcggccc gggtcttcag
     2821 ctcgctgtcc ttcgccgcct cgccgatgtg ccgggacgcg agcttctgca cggcctgctc
     2881 accgttcggg ttgtccgaga acaggtcgcc caggcggtcc agcagcccgc gctgcttgga
     2941 gaccgcgtag gagcggtcgg ggtcgagggc cggctcgccg agcgccgcgt gcggcagccg
     3001 cagcgtggcc gacgtccggt ccccgtcgac ctgcacatcg tcctcgccca gctttccgag
     3061 gtcgacatag gcgtccacgg tacccgcccc cacgtacagg gtgcgggtcc cgcggatcgc
     3121 gtccggcagg aacttggtgt ccttctccag atccacgacg acctggaagt tgccggacgc
     3181 cgcgtcgtaa cggctcatgt cctggatgga cttcagcagc gccggtccgg accggtcctg
     3241 cgtctccgag ccgaacaggt ccttgaggcc gggcaggacg ctcagccgga gcccggcgaa
     3301 cagcaccgcg agcaccagca ccaccgcggt cagcgccttc gcccagccgg gcatgcgcgg
     3361 cgcgggcttc cggtcgtcac tcgtgggctt cttgacggga gtcgtcatgg cgacggccct
     3421 ccttcctact cacccggatg cccctcatct cccctgccag acggagcagt tggagaacgg
     3481 gcggcaggac gcggggatcc cgggtgaatt gcggctgccg ggctcacccg cggggaggcg
     3541 gtgtggtcct cgcgaccgtc gacagccacc tacgatgcac cgtcggccga aaccgtgacg
     3601 gccgccccgg ttcacctcag ccggacaccg tgacggccgc cgggcccgtg tgccgcgccg
     3661 gtggtggtga gccggtcagt accccgttcg gcgagcggtc ggcagggcgg ggccgagtac
     3721 ctcccgcagg gtcggccgcg gtggcagcag ccgggtcagg ccggtgatcc gcagcatgcg
     3781 cagggtgagc gggtgcgagc acaccaggtg aacctctccg ccgcccgcga gcacctggtt
     3841 gcgggcccgg gcgagcagcc ggagcccgga gcagtcgaag aactcgatcc cgccgaggtc
     3901 gagcacgacg cgggcgccgg ggcgccgcgt ctcccggtcc aggtgcgggg cgatctccgt
     3961 ggcggacgcg atgtcgatct cgccccggaa ctccagtacc gcgtgcccgc gctcgtggcg
     4021 cacccgcaga tggcgggtgg gcgacgggga ttcctgccgc acgacgacgt cgcctccagc
     4081 ctgttccggc ccgtttcggc ctgtcatggg ggcccaacta cccagtctgc tcagaaagtt
     4141 acctcggtcg agcgagtttg agcatgttcg actgacatat gtcgccgacg tctcatcgca
     4201 cggccgtgcc gaccgttcag tcgaccacga gaacgatctt gccggtggtg cggccggtct
     4261 cccccagggc gtgcgccccg gccgcctcgg ccagtgggaa cgtcttcgcg atggtgggct
     4321 ccagcttccc cgcctcgacc agccgggcga tctcccgcat gtcggcccgg tcggcgtcga
     4381 ccagcatccg taccgcccgc accccgagcc gcccggcctc ctcgaagaac tcgccggacc
     4441 cgaccggcag gatcgacacc accaccccgc ccgggcgcag cacgcgcagt gacctcagcg
     4501 acgtgtcgcc gccgatcgtg tccaggacga cgtcgacgtc gcgcaccgcc tcggtgaagt
     4561 ccgtctcccg gtagtccacg gcctcgtccg ccccgaggga ccgcaggaac gcgtgcttgc
     4621 ccgcgctggc ggtgccgatg acgtgggcgc cgcgcgcctt ggcgatctgc accgccacgt
     4681 gccccacgcc gccggccgcg gcgtggatca gcacccgctg ccccggctgg aggcccgccc
     4741 gttccaccag ggcctgccac gccgtgaggg acaccagcgg gagcgcgccc gcccggacgt
     4801 ggtcggtccc ggcaggcagg tgcgtgaagg tgcgcgcggg agccgtcacg tactccgcgt
     4861 gcgaaccgtg gccgaaggga taggagagca tgccgaagac ctcgtcgccc ggccggaacg
     4921 cggcgacgcc gatccccacc gactccaccg tgcccgagac gtcccagccc agtacgaagg
     4981 gcggctcgcc gaggaagccg ccgtccgccc ggtgcttcca gtcggtgggg ttcaccccgg
     5041 cggcacgcac ccggaccagc acctcgttcg gccgcggaac ggggcgctcg acccgtacct
     5101 ccttgaggac ctcgggtccg cccagaacgt cctggctgac ggcgcgcatg gtggtcatcg
     5161 gagaacctcg caactcggga ggggggggca ggggcacggt ctgcgactcc gacgtgatcg
     5221 tgccattccc cgggccggac ggcacccgcg ggcgcggcag ccggatcagg gcggcgggcg
     5281 tgctcaggcc ccggtttccc gggcgcaccg tgtcggtgca cctggtcaat tgggggattt
     5341 gtcgacctct ggcccgctgc cgggtcgtga cggaatcctc acttccgcgg agccgtgaaa
     5401 ttgatctttt aggcttccca accgataagc tccccagcgg cactgcgagt tgacgcgatc
     5461 gcgacgggtc ggcccgtggt gcacaccctg agtgcggtcc cccttgcgca cccttgctag
     5521 accatccccc ctgttcgatt gttttgcttc gaaggatgca gatggaactc gccactccgc
     5581 caccggcggc gcgggtccct gtcgcctggc acagctggtg gctcatgcca ctggggctgg
     5641 gcggcgggac ggtagccgcc acgttcatga gctcggagcg aataaccgtg gccgtcgccg
     5701 gcgcggcggc caccgtggcc ggcaccgtgt gcgtacgcct cctcctgcgc acccgcgccc
     5761 agcttggccg ggccgagaac gcccaccgct ccgcgcgctc cgagaactcc cagcagtggc
     5821 agcagcacgt ggccggcctg gaacgcaagt tctccgccga gcgctccgac ctggacgccc
     5881 agctcaccga gcaggcccag acctacgagg aacggctcgc cgagcacacc cgggcctacg
     5941 aggaccggct cgccgagcag gccacgtcct acgaggcccg gttcgccgag cggaccgagg
     6001 cctggcagga gcagctggga caccagctgg ccgcggtgtc ccggctcgcc gacgagcagt
     6061 tgcccgacgc gatgcgcagg ctgcgctccg gcgacgccat cgacgacatc ctgccgaccg
     6121 tcgagcagtg ctccaaggtc ggcgccgacc tccaggccga actgcgcaag gtgctccgta
     6181 ccgcgctgat cggcgtcgag gcggagttcg accgttcgac ctccgcggag caggcggtca
     6241 tcagcgtcgg caaccgcatc cacgtgctga ccagcaagct ccgtggccgc ctgcacgaga
     6301 tgcagggcga gcacgggcgg ctgcccaccg tcgcccgcgg cctgatggaa ctcgaccagg
     6361 ccatcggccc cgcggactgc ctcgccgcca gcatcggcgt gctcggcggc tcggaccgcc
     6421 cgggacggca gtggcaggaa ccgcagcggc tgctgagcgt gatgcgcggc ggcatcggcc
     6481 ggatcaagga cttccaccgc gtccagctgc gccacctgcc cgaactgggt gtcgacggcg
     6541 gcctggtgga ccacctcacg ctgatcttcg cccacctgct ggacaacgcc gcgcgctact
     6601 cgccgcccac cgagccggtg gtcgtctccg gcaaggaggt gcccaacggc gtcggcatcg
     6661 agatccagga ctccggcaag ggcctgagcg acgagaagaa gcgcgaggcc gagcacgcgc
     6721 tggccggcac ctcgcccggt gcgggactcg gcggcatctc ggaggacgcc aacatcggcc
     6781 tccgcgtcgt cggcgccctc gcccgccgct acggcatccg ggtcaccttc gccgactcgc
     6841 cgtggctggg cacgtccgtg gtggtcgtcg taccccacaa gtacttcagc ccgctgccgt
     6901 ccgccgcggc ccccgcgacc gtgccggaca ccgcgcaggc cgccaccgcc cccgcggcgg
     6961 acctcgtgcc cccggcggtc gtcgaggcgg cggccgcccc cgcaccggcg gtcgagtcca
     7021 cacgggcggc cgaccccgcg cccgcggccg acaccgcggt ggagaccacc ccgggcggcc
     7081 tgccccgacg ccggagcagg cgggccgaac cggccgccgc gtccggggcc gccgcgccgg
     7141 ccgcgcagca gcccgggagc gaagccgccg accgggccca ggcctccgcc gttccaccgg
     7201 acgcgtcctt caccggtctc gccgccttcg ccaccgcggg ccgcgacccc ggcgccggcg
     7261 tcggcacctc cgaatcgacc accggtggcg cgtccaccga gcaccgcact gaagagagcg
     7321 actagtcccc atgacgcacc agggaaccga cgtgagctgg gcgctccgcg accttgtgga
     7381 gagcatccag gagatccgct tcgccctcgt tgcctccagc gacggcaagg cgatcacttc
     7441 ctacggcgcc gaagaccccg acgacgtgga ccgcttcgcc gccgtggtgg ccggcctgca
     7501 ggcgctggcc cagccggtgg ccgagcagtt cccgcagcac gcggggcagc tgcggctggc
     7561 gatgatcgag gtggacggcg ggcacctgtt cgtcgtccgg gcgggcatgg agacgtatct
     7621 cggcgtcctc gcccgcgaag gactcgacca gggcctgctg ggccatcaga tgcgcgacct
     7681 ggcccgccgg atgggtgaac tcctcgggac cacgccgcgc caggaggagc actctggatg
     7741 agtgctcccc gccgaccgac cgatccgtcc ggtctcgagc gctactacgt cctcaccgga
     7801 gggcgcagcg ggccgggcgg ttcggcgtcg accctcgacg tggcgacgct cgtcgtcgcg
     7861 cgtgccgccc ccttaccggg catgcagcac gagcacgagg agatcctccg gcgctgccgc
     7921 gacccgcttt cggtggccga actcggcgcc catctgcact tgcccttcaa cattctcgcg
     7981 gtgctgctgt ccgacctgct ccaggcgggc agcgtcgaag cccgtgatcc catcccggca
     8041 ctggatgccg gccgcgggcc cgacctcgcg ctccttgagg aggtactcag tggacttcaa
     8101 aggctttgac cgaccggggt catccacggc gggggacacc cgctcggtga aggtgatgat
     8161 cgccggcggc ttcggaacgg gcaagaccac catggtccgc gccgtcagcg acatcaaacc
     8221 gctgaccacc gaggagaccc tcacccaggc cagcgccgac gtcgaccccc tcatcggggt
     8281 ggccgacaag acgcagacca cggtcagcct ggacttcggc aagatcggcc tcaacgagac
     8341 gctgatgctg tacctgttcg gcaccccggg ccaggaacgc ttctggttcc tgtggaacgg
     8401 cctgttcaag ggcgccctcg gcgcggtcgt cctggtggac acccggcggc tggcctccag
     8461 cttccgggcg atcgaggaga tggagcggca gaaggtcccc ttcgtcatcg cgctcaacgt
     8521 cttccccgac tcgcgcgact acccggtcga cgagatccgc gacgccctgg acatcgcgcc
     8581 gcacaccccg gtcgtcgcct tcgacgcccg cgaccccaca gccggccgcg acgtgctggt
     8641 caccctgatc cgtcacctga aggaccgctc ggccgccgcc ctggagcccc gatgaacgac
     8701 gaccagaccc cgtccgcccc cacgggcggc ggctgccccg tcgcccacgg cgagggcgcc
     8761 gtccggctct acggacccga cgcggcgacc gacccgcaca agatctacgc gcggctgcgg
     8821 ggcgagcacg gggcggtcgc gccggtactg ctggaggacg acgtccccgc ctggctggtg
     8881 ctcggctacc gggagaaccg gcgggtgctg gacaaccccc tccagttcag ccgcgactcg
     8941 cggatctggc gggacttcca ggacggccgg gtcgcggaga cggcgccgct gatgcagatg
     9001 gtggggtggc ggcccgactg cgtctcccag gacggcgaac cgcaccgccg gctgcgcggc
     9061 gcggtcaccg acaacctgta cgccgtcgcg ggacgcggca tcaggcggca catcacgcac
     9121 ttcgccaaca agcagatcga cgcgttcgcc gacgagggcc gcgccgatct ggtggccgac
     9181 ttcgccgagt acctgcccat gctggtcctc acccgggtct tcggcctcgc cgagcgggag
     9241 ggacgcaccc tcgccgagtc cagcaaccag gtgatcaagg gcggcgcgga cgccctcacg
     9301 cacaacgagc gcatcatggg catcctcggt gaactcgccg agcgcaagcg cagggagccg
     9361 gggtccgact tcgcctccgg tctcatcgag cacaactccg gcctcgacga ggacgagatc
     9421 gtcaaccacc tgcgcctggt gctgatcacc gcccacacca cgaccagcaa cctgctggcc
     9481 cgggtgctgc agctcgtcct caccgactcc gcccggctgt ccggcctggt gagcgggcag
     9541 ctgaacatgt ccgcggtggt ggaggaggtc atgtggaact ctccgccgct cgccgtgctg
     9601 ccgggccggt tcgccaccgc cgacctggaa ctgggcggct gcccggtcaa ggagggcgac
     9661 ctgctcgtgc tgggcctcac ggccggcaac cacgaccccg agatccgccc cgacaccggc
     9721 gtctcggtcg agggcaacgc ctcgcacctc gccttcagcg cgggccccca cgaatgcccg
     9781 gggcagaaca tcggccaggc catcatcgag acggccgtcg atgtcctgct gcaccgcctg
     9841 ccgggcctgc gcctggccgt gccggcgtcc gagctgacct ccacggcctc cacctgggag
     9901 tcccgactgg acagcctgcc ggtggagttc gcccgatagc cgcgggaccg agcgaaagcc
     9961 gccgcccggc cggaacaccg gccgggcggc ggctttcgtc ctacacgccc agcaggtcgt
    10021 ccaccgagcc ccgcccggcc tgttcggccg tggcgaccgg gccgtccttg gccgccgcgt
    10081 agcgaccggt cgtcagcgcc cactcgtagt tgccgttgat ccagtgctgg atggcctcca
    10141 cgcccagccg cacccgcgtg cgcccgtcgc cgtcgagacc cagctcgtcg cacatctgcg
    10201 gcacgcgcgc ctccagggcg acgtactcgt cgaggcagtc ggtcgtcatg cggtacgcct
    10261 cgtcggccgc ctcctgccag gagcagcccc gctcgcgctg cagcacggcg acgaggttgt
    10321 gcccgtcgcc gcggcggcgc tcgcgctcga aggagtggat gtcgttcatg aacccgatgg
    10381 tgtccgcggc caggtcccgc atccgctcca tcagcgggtg cgccatcgcc gcggccggca
    10441 cctcgaagcc gcggctgcgc tcgcccgcgt cgatgctgtg gtggatgccg accgtgcggc
    10501 gccggaagac ggcgtactcc tcgatcccca gcgtggcggc ccggccgtgg gccgccaggt
    10561 cgacctcctc gcagtgcgcc accaggaacc ggccccagga cgccgcgaac cgggacttcc
    10621 acgtcaggga catgccatcc gaaaggtgac cccagacctc cgcccacgcc agcgtgatgg
    10681 ggcactccac gcgcggcggg gtccccgccg gacgcagcgg cgtggcgatg agttcccggg
    10741 ccacctcggc tatgcgctcc gcgcggtccg gccgggcggc gtcgaactgg tcgtcgaaga
    10801 ggaaggccag cgagaaccag ttcatcagga cgaccatgtc gtcggccgac gcgtgcgggt
    10861 aggtgcgggc ggcggcctcg gagaggtccc aggagcggta ctcctcgaag cccgccgcgc
    10921 tgcgcaccag cccccgctcg cgcacccagc gcagatggcg ctcacgggcg tgggcgagat
    10981 gcgggctgac gggggtgtcg aaggggaggt cgaagcggac gtcctgcatg tggttccttt
    11041 cgggagacgg agcgcagagt ccccccggcc ctgcgagcgg acggcggcag ggccgcccgc
    11101 gcactcgaac tcggcttcac ggaaagaaag ttgaaccgag aagcgatacg aggctgcccg
    11161 taccctaaat gatctacacg gcgtccgctg gtgatctccg ttactcccgg ctccgccggg
    11221 tatccgcaca gtacgaggtg tggggcagac cgccccacac ccggcatctc cggaggggaa
    11281 cgagacgaca tggcactggt caacgcgggc gtcgtggtgc tcgactgcgc cgagcccgag
    11341 cggctcgcag agttctacaa gggcctgctg ggggcggagg agacggacgt gaccgccaac
    11401 cggatcgaga tcgaggggcc gcgcggcttc cgcctggcct tccggcggga cgtcaacgcc
    11461 accccgccca gctggccccg cccggagaat tcgctccagg tccacctgga cctcgtggtg
    11521 gcggacctgg acgaggccga gcgcgcgatc gtcgggctcg gcgggcggcc ggtggaggcc
    11581 aaggacgcgg cggggccgca cgaggaacgc ggcttctccg acccggcggg gcactccttc
    11641 accctgcgcc tggccgtcgc gccgacggca cccaagcagg gctgaacgcg gcctgccggg
    11701 tgccgtcgcg gcgggggagg ggcggtgcgg tcagtcccgc ccgcccttgc cggggatcgg
    11761 ccaggtgccg gtggagcgct cgatggcctt cgcgccggtc cggtccacgg cactgcgcac
    11821 cgccgcgaag atggcgccct ggatcgcggc ggccagcagg atctcccccc agccgcggtc
    11881 cgggtcgagc gcgtcgggcg cgtcgtcctc gtcgcggatc agcttccagg tcttctggaa
    11941 ggccagtccg gccagcgtgc cgcccagcca cccgagcgcg aagcccaccg gtttgtaggc
    12001 gagcgggagc ttcttcttct ttgtcttcgc catgcggatc tccttgcgcg ctgtgcgatg
    12061 tgaagcgggg aaacggtgga agcggtggga cggtgctgga acgggacggc gttggaaggg
    12121 gtcagggcct gccgcgcgcc ggcacctcct cctcggcacg gaccgggccc ggcggcgtcc
    12181 cgtcgccgaa cggccggccg cccagctcct cgcggtggtg gggcgcgagc cagccagcca
    12241 ggtccgggcc cagcgggacg atgccggtcg ggttgatgcc ggtgtgcacc tggtagtagt
    12301 gccgcttgat gtggtcgaag tcgacggtgt ccccgaaacc gggcgtctgg aacaggtcgc
    12361 ggacgtacgc ccacagcacc gggttctccg ccagcttcca gcggttgcac ttgaagtgac
    12421 cgtggtagac ggcgtcgaag cggaccagcg tcgtgaacag gcggatgtcc gcctccgtga
    12481 ccgtgtcgcc gaccaggtag cgctgtccct ccagccgggg cgtcagctgt tccaggcgcc
    12541 ggaagacgcc cgtgcacgcc gcctcgtact cctcctggcc ggtcgcgaag cccgcccggt
    12601 acacgccgtt gttgacgtcc tcgtagacgc ccgccatgac ctcgtcgatc tcggcgcgca
    12661 gcgcctcggg atacaggtcg ggcgcgcccg gccggtgcag ggcggcccac tcggtggcga
    12721 ggtccagggt gatctgctgg tagtcgttgg tgaccagctt cccgctgggc acgtccacca
    12781 ccgccggcac gctcactccg cccgggtagc ccgtctcccg gcggtcgtag gcctcactga
    12841 ggaagcggat gccgaggacc gggtcgcggc cgtccgggtc cagggtgaac cgccagctgc
    12901 ggtcgtcctg gaccgggtcg gcgaccgcca gggacagggc gtcctccagg ccgagcagcc
    12961 gccgggagac cagggcccgg ctcgcccacg gacaggcgcg gctgaccacc aggcggtagc
    13021 ggccgggttc caccggccag ccgtcccggc cgtccgcggt gatccggtcc gcgaaatggc
    13081 tccgggaccg cttgaaggcc ttcctgccgt aaccgctgtt gcccggcgtc gcgtcgtcgc
    13141 cgctcatggg tctgcctccc gtcgttcgtc tgccatgctg gacgcgttcc ccgttttcgg
    13201 ccgtcggcac tggcgggcca cccgcacggc gggtgtgagg ggcgcggccg ggggcagtcg
    13261 ggccttcgtg agtgagtcag cctcggaaca gaaacccggc cgcgacggcg agagcagggc
    13321 cgatcgcaga acgcgcgtca ccgtgctcgt ggccctggcc gccaacctgg tcatcgcggt
    13381 cgccaaggcc gtcggcggct tcttcgcggg ctcaccggcc ctgctgtcgg aggcggcgca
    13441 ctcggtggcc gacagcatga acgagatctt cctcctcgcc gctctgcgcc gcagccgccg
    13501 gcccgccgac cggcggcacc ccttcggcta cggcaaggag cggttcttct ggtcgctgct
    13561 cgccgccgtc ggcatcttcg tgatgggcgg ctgcttctcc ttcttccagg gcgtcgaggc
    13621 cctgcgctcc ggcgccgagg aggaactgag cggctacgtc gccggactga tcgtgctcgg
    13681 tgtcgccctg ctcgccgagg gcgcctccct gctgcgcgcc ctgcaccagg tacgcgggca
    13741 gggcggtctc gccaccgggc tgcgcgaccc ggcgctgcgc acggtggtcg ccgaggacgg
    13801 cacggccgtg ctcggcgtca ccctcgccat gatcggcatg gtcctgcaca tggtcaccgg
    13861 gcaggtggtg tgggaggcct gcgcctcgct cgccatcggc gcgctgctcg tgtacgtggc
    13921 ctaccgcctg ggccgcgagg cccgcgacca gctgatcggc gaggccgccg accccgaggc
    13981 cgacgggcgg atccgcgagc tgctgcgggc gcagccggag atcgacagcg tcgaggcgct
    14041 gttcaccatg aagaccggcc tcgactccgc tctggtggcc gctcgcgtcg acctggtgcc
    14101 gggcctggac agcgaggagg tggaggaggc cgcggtgcgc atcaagcggt cgatcgccca
    14161 caccgtgccc gaggccgggc aggtcttcct cgacgtcacc gaccgtcccg cgcgggaggc
    14221 ggcgcaaagc cccgccgcga cgggggagcg cggcggggcc tgagcgtcgt gtgcccggca
    14281 cgcgacggtc catgccgtcg ggtccgcggg tccgggagaa gtcccgtgcg ccggatcagc
    14341 cggcgtcggc cggctccagg acgaagacgg gaatctcccg gcccgtcttc ttctggtagt
    14401 ccgcgtacgg cggatacgcc gcgaccgcgc gctcccacca ctcggccttc tccgcgccgg
    14461 tgacctcacg ggccgtcatg tcctgtttcc gcggaccgtc ctggagctcc acgtgcggct
    14521 cggccagcac gttgaagtac cagaccgggt gcttgggcgc cccgcccagg gaggcgaccg
    14581 cggcgtaccg gccgtcgtgc tcgacccgca tcagcggcgt cttgcggatc ttgccgctgc
    14641 gcgcaccccg gctggtcagc acgatcacgg gcaggcccgt gtccgggtga gtggtgccct
    14701 cggtgccgcc cgagccctcg tacagctcga cctgatcccg gacccactgc gtcgggctgg
    14761 gttcgtactc gccctcaaga ggcatctgtg catccgtccc atcgtcgcgt cgtcggaccg
    14821 cccggccggt gcggaccacc gggccgtgcg gaacccgtcc gtccatcctg catcctgccc
    14881 tgtacccccg aacaccgcgc ggacatccgg agcgggcgcg tccgttcgcg gccggaacgg
    14941 gacaatcccg gccgcacccg ggggccgggc ggtcccgccg aacgacgcga tcaggccacg
    15001 cccaccgtcc gtcgcggccg cggggagggc cccgggcgtc cctcacccgg cggtccccgg
    15061 ccactctgcc catgccaccg gtctggccga acttgacgtg gccacatagg tgcccagggc
    15121 atctaattta gctcggcacg aggcaccgat ttcgtctgcg aggtcttcca tgacggacac
    15181 gacgactgac ccggacacga cgcgacccgt cgcctacccg caggacagga cctgccccta
    15241 ccacccgccc gccgcctacg acccgctgcg caccggcccg ccgctcgccc ccgtcaccct
    15301 gttcgacggc cgccccgcct ggctcgtgac cggccacacc ctcgcccgcc ggctcctcgt
    15361 cgaccagcgg ctgtcgaccg accgcacccg cgacggcttc cccctcacct cgccccggct
    15421 ggccgggata cgcagccgca agctggccct gctcggtgtc gacgacccgg aacaccgcgc
    15481 ccagcgcaag atggtgcttc ccgagttcac cctcaaacgc gccgccgccc tgcgcccgcg
    15541 catccaggag atcgtcgacg agcgcctcga cgcgatgatc gcggcaggcc cgcccgccga
    15601 cctggtgcag gccttcgcgc tgccggtgcc ctccatggtg atctgcgcgc tgctcggagt
    15661 cccctacgcc gaccacgagt tcttcgagga gcagtcccgg cggctgctgc gcggcccgct
    15721 gccggccgac gtgcgcgacg cccgggaccg actcgagtcc tacctggggg agctgatcga
    15781 cggcaagcgg acctcgcccg gcgacggcct gctcgacgac ctcatccggg accggctgga
    15841 ggagggcgag atcgaccgcg agcagctcat ctccttcgcc gtgatcctgc tgatcgccgg
    15901 ccacgagacc accgccaaca tgatctcgct gggcacctac acgctcctgg agaaccccgg
    15961 gcgcctggcc gagctgcgcg aggaccccgc gctgctgccc ggcgcggtcg aggagctgat
    16021 gcgcatgctg tcgatcgcgg acagcctgct gcggacggcc accgaggaca tggaggtgga
    16081 agggcacacc atccgggccg gcgacggggt ggtcttctcg acctccgtca tcaaccgcga
    16141 cgggaccgtc tacccggagc cggacgccat cgactggcac cgcccggccc gtcaccacgt
    16201 cgccttcggc ttcggcattc accagtgcct gggccagaac ctcgcccgcg ccgaactgga
    16261 gatcgccctg cgcaccctct tcgagaggct gcccacgctg cgcctggccg tacccgccca
    16321 ggagatcccc cacaaacccg gcgacacgat ccaggggatg ctggaactcc ccgtggcctg
    16381 gtaggagggt ccggacatgg caacgggcat ggacatcggt atcgacaagg acgtctgcat
    16441 cggcgccggt cagtgcgcaa tgaccgcccc ggacgtgttc acccaggacg acgacggcta
    16501 cagcaccctg caggccggcc gggaggacgg cggcggcagc cccctggtcc gggaggcggc
    16561 ccgggcgtgc ccggtcggcg ccatcaccgt gtcggagcgg gtgggctgac cccggggcgt
    16621 tcggctcccc cggggcccgt cccttagggt tccggggtga gcgaacaggc cgggaacagt
    16681 cgacgggccg cgagcggcaa accggtgccg gacggcggac cggcggggaa ccgcgaaccg
    16741 gcgcgaaccg gagcacgggc gggggacggt gacccgggcg gcagcaaggg cgaccccttc
    16801 ctctacgtcg tcgtctgtgc ggccggcgtg gcgtccggcg tcggcgcact gatcgacgcc
    16861 gccctgcgac gcgactggga ggtgggcgtc ttcgcgaccc cggtcgccat ggacggcttc
    16921 ttcgacaccg ccgacgtgga ggcccgcacc gggcgcccca tccgctcggc gtggcgacgc
    16981 cccggcgagc cgcgcccctt cccggccccg gacgccgtcg tggtcgcccc cgccaccttc
    17041 aacaccgtca acaagtgggc cgcgggcctg gccgacaccc tcgccgtggc caccctgtgc
    17101 gaggcctgcg gcctcggcgt tcccgtcggt gtcctgccgt gcgtctccga cgcgctggcc
    17161 tcgcaccccg cctaccgggc gagcctggac cggctgcgcg ggatgggtgt gcgcttcggc
    17221 gacccgtacg agggcggggc ggcgggcggc gaccggcggt tccactggga gcgcgccctg
    17281 gacctgctcg aacggcgctg accggggtgg cgttggagtg cgcgcgaagt cgtacgctcg
    17341 ccctgtaccg atgatcccga gaacacagga gcagcaacga tgcagtacgt gaagctcggt
    17401 tcgacgggcc tcgacgtgtc gcggatctgc ctgggctgca tgacctacgg cgtccccggc
    17461 cgcggcgccc acgagtggac cctcgacgag gacgccgcgc gtccgctgat ccggcaggcg
    17521 ctggaggccg gggtcacctt cttcgacacg gccaacgtct actccgacgg caccagcgag
    17581 gagatcgtcg gcaaggcgct gcgggacttc gcccgccgcg acgacttcgt gctggcgacc
    17641 aaggtgcacg gccggatgcg gcccgggccc aacggagccg ggctgtcccg caaggcgatc
    17701 atgaccgaga tcgaccacag cctccggcgg ctgggcaccg accacgtgga cctgtaccag
    17761 atccaccgct acgacccgca cacgccggtc gaggagacga tggaggccct gcacgacctg
    17821 gtgaaggcgg gcaaggtccg ttacctcggg gccagttcga tgtacgcgtg gcagttctcc
    17881 aaggcccagt acacggccga gcggcacggc tggacgaagt tcgtgtccat gcagaaccac
    17941 tacaacctcg tgtaccgcga ggaggagcgc gagatgctgc ccctgtgcgc ggaccagggc
    18001 gtgggagtac tgccctggag cccgctcgcc cgcggccggc tcacccgcga ctgggacacc
    18061 gccaccgggc gcagcgccac ggacgcgttc ggcagcaccc tctacccgga gggcgaccgc
    18121 gccgtggtcg aggcggtgac ccgcatcgcc ggcgagcgcg gcgtgccgcg cgcccaggtg
    18181 gccctcgcct ggctgctgca ccaggacacg gtgaccgccc cgatcgtggg cgcgtcgaag
    18241 ccggggcaca tcgaggacgc cgtggccgcg gtcgaactgg tcctcggcga gaaggagatc
    18301 gaggagctgg agagccccta cacgccgcac ccggtcgccg gtcactgacg gtcgggccgt
    18361 gcgagggggg caccgtgccg gtgccggtgc gggtgggtca ggggccggtc cccgcctcca
    18421 gggcggtgac ggacaccgac gacgcgttgc cgcccaccgg gaccgcaccg gccgtccact
    18481 ccaccttgag ggaggcccgc tcgtccggcg gcgtgaccag cagcgcggcc ggggtcgcgg
    18541 tgcgggcgcc gctgatctcg gggctggaga acgacagccc ggcccacgcg ctcgcgccgg
    18601 gcgtcagcgt gagggtctcg ggcgagccgg gcgcgcgctc cgggtccggg ccgagttgct
    18661 tgccggacgc gtccacgaag gcggcgcccg gatagccgta caccgtgcac gtgcgctcgg
    18721 aggtgttggt caggacgagc gggaagttcc gctgtccggc gcccgggtcg agccggccga
    18781 cggcggcccg caactcggag gtgtggcagc ggccgtcggt gcgggcggag gccgacgcgg
    18841 acccggcggt gtcgctgggc gtgccggccg ccgccgcggt gccggggtcg gtggcggtgc
    18901 cggtgcccgc gctcggggcc gcgtccgagg cgcgggcgga gtgcgagggc gggggcgtgc
    18961 cggacgtgcc gttctcgctg ccgcaggcgc tcagcaggcc gaggaccgcg agtccgctcg
    19021 cgagcagggc cgtccggcgc accggctggg acgtgttggc catggcttcc tcacactccc
    19081 gtggtttccg cgcacgcctg ccgtggcgcc gtgcgccctg tactccgggt gtcccgtcgc
    19141 acggcccggg aaacggcgac ggctcactcc tcctcgacca ggcccagctc ggcccagatc
    19201 gtcttgccct ccgtcgtgtg cctgctgccc cagcgctggg tgagctgggc caccagcagc
    19261 agaccgcgcc cgccctcgtc ccaggtgcgg gcccggcgca ggtggggcgc ggtgtgactg
    19321 ctgtcggaga cctcgcagat cagcgtggtc gcgtcgtgga tgagccgcag ccggatgggc
    19381 ggggagccgt accggatcgc gttggtgacc agctcgctca ccaccagctc gacggtgaag
    19441 gaggcatccg tccgacccca gacggcgagc tggtcgagca cctgcttgcg caccggggcg
    19501 accagcgacg ggtcggccgg gatgtcccag gtggccacct gcccggtggg cagcccccgg
    19561 gtgcgggcca gcagcagggc cacgtcgtcg ccggcgctgc ccgccgggag caggctgtgc
    19621 agcacccggt cgcaggcggc gtccagcgag gcgccgggcg cggccagcgc ctcgcacagc
    19681 agtgccaggc cggcgtcggg gtcccggtcc cggctctcga ccagtccgtc ggtgtagagc
    19741 gccaggatgc tgccctcgcg caactccagc tcggccgact cgaagggcag cccgcccacg
    19801 cccagcggtg gccccgaggg cagctcgacc tgccgcgccg ggccgtccgg cggcaccagg
    19861 acgggcgccg ggtgcccggc cctggccatg gcgcagtgcc gcgagaccgg gtcgtacacc
    19921 gcgtacaggc aggtggcgcc gacctcgccg gcccggtcgt cgccggactc ctcggagagg
    19981 cggacgacca ggtcgtcgag gtgggtgagc agctcctcgg gcgtcaggtc gatgtcggcg
    20041 agggtgcgta cggcggtgcg cagccgcccc atggtggccg acgccgcgat gccgtgcccg
    20101 acgacgtccc cgacgaccat ggcgacccgc atcccggaca gcgggatgac gtcgaaccag
    20161 tcgccgccga cgcccgagcg ggccgccgga aggtagcggg aggccgcctg caccgctgcg
    20221 gtgggcggca gccaccgggg cagcaggctg cgttgcaggg tcagggtggc ctcgcgctcg
    20281 cgcgagtagc ggcgggcgtt gtcgatgcag acggcggcgc gggcgctgac ctcctcggcc
    20341 agcaggacgt cgtcgtgcgt gaacgggtgc aggcgccgga accggatgaa gaccgccacg
    20401 ccgagggtgg tgccgcgggc ctggagcggt accgacatca cggagtggac gccgtgctcc
    20461 cgcacctgcc gcaggcgcgc cgggtcccag cccatccagc gctccaggtc gccgtgcgcc
    20521 tcggcggcca cgatcgcccg gccggagagc aggcactcgg cctggggcga gcccgccggg
    20581 tagaagtcca gccggccggt ctcggcggcc gcaggcggac acgtcgacga gtgggcagag
    20641 ccggccgagt ggtcgggcag gtgcgtccgg tgggccgtcc ggcgcaggcc gaccggtggt
    20701 tcgaccacgg tggcgggctc accgccgttg tcccgcgggt ccagcaggtc gacgctcacg
    20761 aagtcggcga gcgcgggcac gcacacgtcc gccagttcct cggcggtgcg gttgacgtcg
    20821 agggtgctgc cgacccgcac gctggcctcg ttgaccagtt gcagccgctc ccgggcgagg
    20881 tgctgctcgg tgaagtcgtg ggcgctcacg cacacgccgc gcaccagccc gtcggcgtcg
    20941 gtgagcggcg ccatcagggc gacccaggcg tgggcgcgct cctcgccctc ggccctcaga
    21001 tgactgcgca ggtcctgccg ccggccggt
//
