LOCUS       NZ_CP094676            22649 bp    DNA     linear   CON 30-MAY-2024
DEFINITION  Streptomyces sp. CB09030 chromosome, complete genome.
ACCESSION   NZ_CP094676
VERSION     NZ_CP094676.1
KEYWORDS    RefSeq.
SOURCE      Streptomyces sp. CB09030
  ORGANISM  Streptomyces sp. CB09030
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1  (bases 1 to 8368456)
  AUTHORS   Shi,J. and Huang,Y.
  TITLE     Genomic of Streptomyces sp. CB09030
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 8368456)
  AUTHORS   Shi,J. and Huang,Y.
  TITLE     Direct Submission
  JOURNAL   Submitted (10-FEB-2022) Xiangya International Academy of
            Translational Medicine, Central South University, Changsha, Hunan
            410013, China
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: 2021
            Assembly Method                   :: Canu v. v1.5; Racon v. v3.4.3
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 1510.0x
            Sequencing Technology             :: Oxford Nanopore
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_022827705.1-RS_2024_05_30
            Annotation Date                   :: 05/30/2024 05:11:20
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 7,205
            CDSs (total)                      :: 7,118
            Genes (coding)                    :: 7,015
            CDSs (with protein)               :: 7,015
            Genes (RNA)                       :: 87
            rRNAs                             :: 6, 6, 6 (5S, 16S, 23S)
            complete rRNAs                    :: 6, 6, 6 (5S, 16S, 23S)
            tRNAs                             :: 66
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 103
            CDSs (without protein)            :: 103
            Pseudo Genes (ambiguous residues) :: 0 of 103
            Pseudo Genes (frameshifted)       :: 40 of 103
            Pseudo Genes (incomplete)         :: 75 of 103
            Pseudo Genes (internal stop)      :: 10 of 103
            Pseudo Genes (multiple problems)  :: 21 of 103
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 20:41:32
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 2159331
            Orig. end                         :: 2181980
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP094676.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..22649
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="lanthipeptide-class-iii"
                     /region_number="9"
                     /rules="(micKC and not PKS_KS)"
                     /tool="antismash"
     cand_cluster    1..22649
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(micKC and not PKS_KS)"
                     /kind="single"
                     /product="lanthipeptide-class-iii"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..22649
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:12649](+)"
                     /cutoff="20000"
                     /detection_rule="(micKC and not PKS_KS)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-iii"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..12649
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(micKC and not PKS_KS)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-iii"
                     /protocluster_number="1"
     gene            727..1125
                     /locus_tag="L6J92_RS09630"
                     /old_locus_tag="L6J92_09630"
     CDS             727..1125
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007385230.1"
                     /locus_tag="L6J92_RS09630"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="L6J92_09630"
                     /product="OB-fold nucleic acid binding domain-containing
                     protein"
                     /protein_id="WP_078535994.1"
                     /transl_table=11
                     /translation="MSAAPRSDKPVGRFRRMFDRLSSSQEDLESEELREDTDTTGCTRI
                     GDCQDRQVVSVTGTLRTVTQRPRAGVPALEAELFDGSAALDVVWLGRRSIVGIEPGRKL
                     IASGRVSMSHGRRVLFNPKYELRPLGRE"
     gene            1129..1950
                     /locus_tag="L6J92_RS09635"
                     /old_locus_tag="L6J92_09635"
     CDS             1129..1950
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003973147.1"
                     /locus_tag="L6J92_RS09635"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="L6J92_09635"
                     /product="DUF3159 domain-containing protein"
                     /protein_id="WP_194275646.1"
                     /transl_table=11
                     /translation="MTSLDKPTEDTTEADDSRAVTEAALFEAFGGVRGMIETVLPGLLF
                     VTIFTLNNDLHMSAIAALAVSLVLVVVRLVMKDTVKHAFSGVFGVAFGVVFAMMTDNAK
                     NFYLPGMLYTLGLALAYIVTSLAGVPLIGLILGPVFKENLSWRTRNPGRKKAYTKASYA
                     WGLILLAKSAILFPLYWFADTEQLGWVLVTLKIPPFLLAVWLTWVFLAKAPAPIDVFAE
                     MEAAEEAEKAEKAGRERREQEADGTLPGPPSGADGADVEGADLRGGRHRKA"
     gene            complement(2172..2852)
                     /locus_tag="L6J92_RS09640"
                     /old_locus_tag="L6J92_09640"
     CDS             complement(2172..2852)
                     /GO_process="GO:0006813 - potassium ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003973146.1"
                     /locus_tag="L6J92_RS09640"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="L6J92_09640"
                     /product="TrkA family potassium uptake protein"
                     /protein_id="WP_031035218.1"
                     /transl_table=11
                     /translation="MRVAIAGAGAVGRSIAGELLENGHEVLLIDKAPTAISVERVPMAE
                     WLLADACEITSLDEAALQRCNVVIAATGDDKVNLVVSLLAKTEYGVPRVVARVNNPKNE
                     WLFNESWGVDVAVSTPRLMSALVEEAVSVGDLVRLLRFSHGDANLVELTLPEESALAGT
                     QVGDVQWPEDTSLVTIIRGTRVLTPSREDSLEAGDELLFVAAQAREEQLEDLLSARRRP
                     DGTV"
     gene            complement(2852..3523)
                     /locus_tag="L6J92_RS09645"
                     /old_locus_tag="L6J92_09645"
     CDS             complement(2852..3523)
                     /GO_process="GO:0006813 - potassium ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019072970.1"
                     /locus_tag="L6J92_RS09645"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="L6J92_09645"
                     /product="TrkA family potassium uptake protein"
                     /protein_id="WP_243780888.1"
                     /transl_table=11
                     /translation="MHIVIMGCGRVGSALAQNLEQQGHTVAVIDQDPTAFRRLGSSFGG
                     RRVTGIGFDQDTLREAGIEDAGAFAAVSSGDNSNIIAARVAREMFGVENVAARIYDPRR
                     AEVYQRLGIPTVATVRWTADQMLRRLLPSGAEPLWRDPTGGVQLAEVHTSSYWVGHKIS
                     RLQEETGVRVAFVTRLGEAILPTSQTVLQEGDLVHVMMRTDEVHKVEAAFAKGPEEEGG
                     H"
     misc_feature    3562..3576
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: weak, score: 17.14"
                     /tool="antismash"
     gene            complement(3767..3928)
                     /locus_tag="L6J92_RS09650"
                     /old_locus_tag="L6J92_09650"
     CDS             complement(3767..3928)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="L6J92_RS09650"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="L6J92_09650"
                     /product="hypothetical protein"
                     /protein_id="WP_169752354.1"
                     /transl_table=11
                     /translation="MHLSAELIGGGVTLVGLGILTFASVRSIGRRGTPAEGWHGRPSVH
                     VGDELRRP"
     gene            4111..6186
                     /locus_tag="L6J92_RS09655"
                     /old_locus_tag="L6J92_09655"
     CDS             4111..6186
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1038: phenylalanine-specific permease"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010035059.1"
                     /locus_tag="L6J92_RS09655"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="L6J92_09655"
                     /product="APC family permease"
                     /protein_id="WP_031035213.1"
                     /transl_table=11
                     /translation="MSKLTDVPKRILIGRALRSDRLGETLLPKRIALPVFASDPLSSVA
                     YAPGEVLLVLSIAGVSAYHFSPWIAVAVVVLMFTVVASYRQNVHAYPSGGGDYEVATTN
                     LGPKAGLTVASALLVDYVLTVAVSISSGIENLGSAIPFVVEHKVLCAVAVILLLTLMNL
                     RGVRESGTLFAIPTYVFVAGVFIMIVWGAFRGLVLGDTMRSPTADYEIKPEHGGLAGFA
                     LVFLLLRAFSSGCAALTGVEAISNGVPAFRKPKSKNAGNTLAMMGLLAVTMFCGIIALA
                     SATDVRMSENPATDLFHNGVAVGADYVQHPVISQVAEAVFGEGSFLFVVLAAATALVLF
                     LAANTAYNGFPLLGSILAQDRYLPRQLHTRGDRLAFSNGIVLLAGAAMLLVVVYGADST
                     RLIQLYIVGVFVSFTLSQIGMVRHWNRNLTGERDQARRRHMIRSRAINAFGAFFTGLVL
                     VVVLATKFTHGAWVALLGMCIFFATMTAIRGHYDRVAEEIAAPEDPEEAQSDDMVRPSR
                     VHSVVLISKIHRPALRALAYAKLMRSDSLEALSVNVDPAETKALREEWERRGIAVPLKV
                     LDSPYREITRPVIEYVKGLRKESPRDAVSVIIPEYVVGHWYEHLLHNQSALRLKGRLLF
                     TPGVMVTSVPYQLESSEAARRRARRRQNWSAPGAVRRGPAHHDRTKDSSSSTSSST"
     gene            6241..7617
                     /locus_tag="L6J92_RS09660"
                     /old_locus_tag="L6J92_09660"
     CDS             6241..7617
                     /EC_number="2.1.1.-"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /GO_process="GO:0031167 - rRNA methylation [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PCMT"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003973118.1"
                     /locus_tag="L6J92_RS09660"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="L6J92_09660"
                     /product="class I SAM-dependent RNA methyltransferase"
                     /protein_id="WP_243780889.1"
                     /sec_met_domain="PCMT (E-value: 9.1e-05, bitscore: 21.0,
                     seeds: 9, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MQAEPTNTQAETRATPQPAERPASLVGEEYEVEVGPVAHGGHCVA
                     RTSEGQVLFVRHTLPGERVVARVTEGEEGARFLRADAVEILDASKDRIEAPCPFAGPGR
                     CGGCDWQHAKPGAQRRLKGEVVAEQLQRLAGLTPEEAGWDGTVMPAEGDKLPAGQVPSW
                     RTRVQYAVDADGRPGLRRHRSHEVEPIDHCLIAADGVSELGVEQRDWPGMATVEAIAAT
                     GSQDRQVILTPRPGARLPLVELDRPVSVMRVDEKDGGVHRVHGRSFVRERADGRTYRVG
                     SGGFWQVHPKSADTLVTAVMQGLLPRKGDMALDLYCGVGLFAGALADRVGDQGAVLGIE
                     SGKRAVEDARHNLAGFDRVRVEQGKVESVLPRTGISEVDLVVLDPPRAGAGRKTVQHLT
                     TLSARRIAYVACDPAALARDLAYFRDGGYRVRTLRVFDLFPMTHHVECVAILEPAGKGA
                     "
     gene            7701..7895
                     /locus_tag="L6J92_RS09665"
                     /old_locus_tag="L6J92_09665"
     CDS             7701..7895
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016470322.1"
                     /locus_tag="L6J92_RS09665"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="L6J92_09665"
                     /product="ribbon-helix-helix protein, CopG family"
                     /protein_id="WP_073492303.1"
                     /transl_table=11
                     /translation="MAMTLRLPDDLDAKLTERARREGRSKQELAIEAIRDAQNRAELKV
                     DDVLAELLDSDAEILDYLK"
     gene            7892..8284
                     /locus_tag="L6J92_RS09670"
                     /old_locus_tag="L6J92_09670"
     CDS             7892..8284
                     /GO_function="GO:0016301 - kinase activity [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007504909.1"
                     /locus_tag="L6J92_RS09670"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="L6J92_09670"
                     /product="type II toxin-antitoxin system death-on-curing
                     family toxin"
                     /protein_id="WP_195889486.1"
                     /transl_table=11
                     /translation="MTNVRYVQIDEILAIARTVNGTEHSVRDMGLLVSAIERPRTNVFG
                     AELYPTLHEKAAALLHSVARNHALIDGNKRTAWLATRVFLRFNGVSASTLPPHVSIVGP
                     FVEDVAQDNIDVPVIAKRLAAWFAVS"
     gene            8974..9192
                     /locus_tag="L6J92_RS09675"
                     /old_locus_tag="L6J92_09675"
     CDS             8974..9192
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="L6J92_RS09675"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="L6J92_09675"
                     /product="hypothetical protein"
                     /protein_id="WP_243783179.1"
                     /transl_table=11
                     /translation="MPCSPPICLVGTLVGVGAFADAAIGERAWLELMHFSVMHFPALMD
                     ADFVTERTVAPTPSMGTPCCLSTVTFV"
     gene            complement(<9487..9813)
                     /locus_tag="L6J92_RS09680"
                     /old_locus_tag="L6J92_09680"
                     /pseudo=""
     CDS             complement(<9487..9813)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_086558177.1"
                     /locus_tag="L6J92_RS09680"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /old_locus_tag="L6J92_09680"
                     /product="transposase"
                     /pseudo=""
                     /transl_table=11
                     /translation="MILRQPGGGTAAHVERMASEDLWTVNQRAVPSAPVRPQGGGHRRQ
                     GAREVLATATVLATSGCTWNQLPRTSACRA"
     misc_feature    complement(9577..9579)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     misc_feature    complement(9959..9971)
                     /note="TFBS match to MatP, Cell cycle regulator,
                     confidence: weak, score: 22.13"
                     /tool="antismash"
     gene            10001..12649
                     /gene="lanKC"
                     /locus_tag="L6J92_RS09685"
                     /old_locus_tag="L6J92_09685"
     CDS             10001..12649
                     /GO_function="GO:0004672 - protein kinase activity
                     [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_process="GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /GO_process="GO:0006468 - protein phosphorylation [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="lanKC"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-iii: micKC"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Pkinase"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) LANC_like"
                     /gene_functions="regulatory (smcogs) SMCOG1030:
                     serine/threonine protein kinase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016827685.1"
                     /locus_tag="L6J92_RS09685"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="L6J92_09685"
                     /product="class III lanthionine synthetase LanKC"
                     /protein_id="WP_243780890.1"
                     /sec_met_domain="micKC (E-value: 1.2e-242, bitscore: 806.3,
                     seeds: 18, tool: rule-based-clusters)"
                     /sec_met_domain="Pkinase (E-value: 3.3e-12, bitscore: 45.0,
                     seeds: 54, tool: rule-based-clusters)"
                     /sec_met_domain="LANC_like (E-value: 0.00022, bitscore:
                     18.8, seeds: 47, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNKGYAVYCDADPYFYDAPHRTAPGTAAAGTRYSAATEPVPAGWR
                     RGESGDWLALRPLDADLPAQGWKIHVSACLDNAESVLERVKRHCVEHGVAFKFVPSRYL
                     LHQRNAKYADRSGSGKFITVYPADEEHFERLAGELTALLAGEPGPHILSDLRLGDGPVH
                     VRYGSFTRRDCYDENGDLRPAVAGPDGVLVPDPRGPVFRVPDWVSVPAFLRPHLEARAT
                     TTLTDVPYTVETALHFSNGGGVYRARDTRTGEPVVLKEGRPHAGLAADGADAVTRLERE
                     RRALERLSGLDCTPEVRDAFTVGEHHFLVLEHLDGKPLNTFFARRHPLIEADPGEERLA
                     EYTAWALDIHAQVEEAVAQVHGRGVVFNDLHLFNIMVRDDGRVALLDFEAARHAEEPGR
                     QTVAHPGFVAPSDRRGEAVDRYALACLRLALFLPLTSLLALDRRKAEHLADVVARQFPV
                     PRAFLDAAVAEITGTPVRAVARAAGGGFVPVEPGDWPHSRDSMTAAVRASATPSRDDRL
                     FPGDVAQFATAGGGLAFGHGAAGVLYALAESGAGRDEAGEQWLLERTKEPPAGMPPGFH
                     DGIAGTAWTLDRLGHRARALDLTGRLLEHPLEGLAPDLHSGTAGIGLALDSLAASTGDA
                     ALRAAALRCAELSAHGLPAGAVVRASGRRPRAGLLHGATGRALLFLRLYERTGDTALLD
                     LAGTALRQDLASCVRGAGGALQVDEGWRTMPYLGAGSVGIGMVLDDYLAHRADEEFEQA
                     RTEIVRAAQAMFYAQPGLYRGVAGMVLYLGRTTAPGPGTGPEAVRRQIDALAWHAMSYR
                     GRLAFPGEQMMRLSMDLSTGTAGCLLALASVHGDRSAGLPFLPPPRSVPRPHEPVPPGT
                     VKEAPVVVTKG"
     gene            12654..12782
                     /locus_tag="L6J92_RS09690"
                     /old_locus_tag="L6J92_09690"
     CDS             12654..12782
                     /codon_start=1
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018849360.1"
                     /locus_tag="L6J92_RS09690"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="L6J92_09690"
                     /product="SapB/AmfS family lanthipeptide"
                     /protein_id="WP_016827684.1"
                     /transl_table=11
                     /translation="MNLFDLQSLETPKEEAMGDVETGSRASLLLCGDSSLSVTTCN"
     CDS_motif       12654..12716
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence: MNLFDLQSLETPKEEAMGDVE"
                     /locus_tag="L6J92_RS09690_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       12717..12782
                     /prepeptide="core"
                     /locus_tag="L6J92_RS09690_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class III"
                     /score="30.50"
                     /molecular_weight="1941.2"
                     /monoisotopic_mass="1940.0"
                     /core_sequence="TGSRASLLLCGDSSLSVTTCN"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MNLFDLQSLETPKEEAMGDVE"
                     /leader_location="[12653:12716](+)"
                     /alternative_weights="1959.2"
                     /alternative_weights="1977.2"
                     /alternative_weights="1995.2"
                     /alternative_weights="2013.2"
                     /alternative_weights="2031.3"
                     /alternative_weights="2049.3"
     gene            12911..14713
                     /locus_tag="L6J92_RS09695"
                     /old_locus_tag="L6J92_09695"
     CDS             12911..14713
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1288: ABC
                     transporter related protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004992230.1"
                     /locus_tag="L6J92_RS09695"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="L6J92_09695"
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_243780891.1"
                     /transl_table=11
                     /translation="MDTTAVRRRRGRAGPGRAGADPGRIPELLVLVCSVAASAVAVAQP
                     LVLGRALDLLLRDGDVGPWLAASVALLVGEIVLDALTALFTGRCTARWTASVRSRALTG
                     LLRAVPGATRPYSAGDVATRLTLNASDAGGVPAARAALAASLITPVGALLALFLVDVWA
                     AACVVAGLPVLVLVLRAFARDTGASVRAYQHVQSDIAGRLLEAMEGAETITAAGTTPRE
                     RERVLRPLAELGALGERMWVLHGRALATGGVLVPLLTVAATAVGGLRLAAGALSVGELL
                     AVCRYAQLAAGFGGAATTLGALVRGRTARERTAALDRLPALRHGRRTLPPGGPGVLELR
                     GVRVLRDGAEVLRADGVVVPGGATAAVVGRSGAGKSALAAVAGRLVDPDAGEVLLDGVP
                     LASLTRRSLRAEVGFAFARPVLGAGTVEQAVAAGVRAATPDRVREAVRAAGADAFVRRL
                     PRTYDTPLGDVPLSGGEHQRLGLARAFAHAGRLLVMDDATSSLDTATEHAVDRAMRRML
                     DGTTRLVVAHRPSVAARADLVVWLEDGRVRAVGPHRHLWETAAYRAVFATETEPGAGQA
                     RAEETGVAPPAGDRAASLHGEVRP"
     gene            14710..>16491
                     /locus_tag="L6J92_RS09700"
                     /old_locus_tag="L6J92_09700"
                     /pseudo=""
     CDS             14710..>16491
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1288: ABC
                     transporter related protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010040507.1"
                     /locus_tag="L6J92_RS09700"
                     /note="frameshifted; incomplete; partial in the middle of a
                     contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /old_locus_tag="L6J92_09700"
                     /product="ABC transporter ATP-binding protein"
                     /pseudo=""
                     /transl_table=11
                     /translation="MTSPGAGTATRERGALRRVAPPARRFLADRKGVLARLGAWSVAES
                     AQTFLGGYGVAQAVDRGFLAGDTAAGLGWLGVAAVAVLLGAPVVTGVFAQLARLTEPLR
                     DALVCRAVTRSLAEASARPGGGDRAAVSRLTNQVEIVRDSFAGLVLTLRSFVFTAAGAL
                     LGLFTLDPALLVVVVPPLAGGLALFLVTLRPMSAAQRRALAADEALGDHASRTRGALRD
                     ITACGTREDAARRGERLVEDAAVCARVLARWAAVRTLALGVAGQLPFLLLLLAVPWLRA
                     RGVGTGALLGAFTYLAQSLLPALHTLMTAIGAAGTRLLVVLDRITGTVPPVTAPHAPAS
                     ETAPQAVSPPPPLRRSASTPTPAVELRSVTLSYGARAEPVLDSLDLRVEDGEHLAVVGP
                     SGIGKSTLARVVAGTLAPGGGTVEVAGRPVTGRDPAELGALRALLPQQAYVFTSTVRDN
                     LTYLCPDARTAELRAAVREVGADGLVARLGGLDAPLVPGDLSQGERQLLVLVRAHLSPA
                     RLLLLDEATCHLDAAAEARAEEALARRPGALLVVAHRMSSALRADRVVVLDGVGAVCGT
                     HGDLLGRSPLYRDLVGYW"
     gene            complement(16535..17128)
                     /locus_tag="L6J92_RS09705"
                     /old_locus_tag="L6J92_09705"
     CDS             complement(16535..17128)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1016: LuxR family
                     DNA-binding response regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019328268.1"
                     /locus_tag="L6J92_RS09705"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="L6J92_09705"
                     /product="response regulator transcription factor"
                     /protein_id="WP_195889491.1"
                     /transl_table=11
                     /translation="MVRVLVVHDALLLRSALAQLLLSADRLEVTSMSSRGEESDDDFPA
                     DVCVVDGECLEGLETLCHTPYWERCGTRLVVLAAPERPGVLRRAFDAGALGFVAKDAPS
                     ERLITAVRTVAKGERFLDERLAVALLDASRTPLTARELSVVSQAAQGSPVAEIAAALHL
                     SRGTVRNYLASAIRKVGARNRVDAIRIVQRAGWM"
     gene            complement(17780..18517)
                     /locus_tag="L6J92_RS09710"
                     /old_locus_tag="L6J92_09710"
     CDS             complement(17780..18517)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1001: short-chain dehydrogenase/reductase SDR"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019766102.1"
                     /locus_tag="L6J92_RS09710"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="L6J92_09710"
                     /product="SDR family oxidoreductase"
                     /protein_id="WP_224297419.1"
                     /transl_table=11
                     /translation="MLAVMSEKTIALVTGANKGIGYEIAAGLGARGWSVGVGARDAQRR
                     QDAVAKLRAAGADAFGVPLDVTDGESVTAAVRLFEERAGRLDVLVNNAGVACGRPEEPT
                     AVDPETVRLLLETNVIGVIRVTNAMLPLLRRSEHPRIVNQSSHVGSLTLQTTPGVDLGG
                     ISGGYAPTKTYLNALTIQYAKELNGSSILINSACPGYVATDLNGFSGTQTSEEGAAVAI
                     RLATLPDGGPTGQLCDHNGVVPW"
     gene            18611..19450
                     /locus_tag="L6J92_RS09715"
                     /old_locus_tag="L6J92_09715"
     CDS             18611..19450
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1014: LysR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018550938.1"
                     /locus_tag="L6J92_RS09715"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="L6J92_09715"
                     /product="LysR family transcriptional regulator"
                     /protein_id="WP_195889492.1"
                     /transl_table=11
                     /translation="MELRELRYFVAVAEELHFGKAAQRLGMAQPPLSRAINRLEQRLGT
                     ALLERTSRKVTLTVAGGVLLDEGRAILGAVTAAERRTRRAATAHPGIVLAVKSGTGGEL
                     LTKLLDAYAAESGAVTVELLLCEAHQHQLLLQDGQADAALLHLPFDSAAGLDTETLCTE
                     GQVAILPASHPLASRSHIRMADVTTLPELPMARWPDPSGSYPEGPGAEVRNLTQLFQLV
                     ALSRTTVVVPESSGADLRRDLAAVPVLDAPPVTTVIAWPPHSRLRAVAELVRVATLL"
     gene            complement(19630..20355)
                     /gene="pepE"
                     /locus_tag="L6J92_RS09720"
                     /old_locus_tag="L6J92_09720"
     CDS             complement(19630..20355)
                     /EC_number="3.4.13.21"
                     /GO_function="GO:0008236 - serine-type peptidase activity
                     [Evidence IEA]"
                     /GO_process="GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /gene="pepE"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016470598.1"
                     /locus_tag="L6J92_RS09720"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="L6J92_09720"
                     /product="dipeptidase PepE"
                     /protein_id="WP_194275627.1"
                     /transl_table=11
                     /translation="MKLLLLSNSTAPGHGYLEHAKDEIADTLGDVRDLVFVPYALADHD
                     AYTAKVRAALSPLGVRVTGVHTHADPARAVRDAGAVFVGGGNSFRLLKNLHAHGLVTAT
                     RERVAAGAPYLGSSAGTNMACPTLRTTNDMPIVQPPTFEALGLVPFQINPHYLDASPDS
                     SHMGETRAERLEQFLEENDVPVAALREGTWLRRDGDSLTLGGATTGAVVFDRAAGARET
                     AVGSDLSALLTRSARFDVR"
     gene            complement(20400..21218)
                     /locus_tag="L6J92_RS09725"
                     /old_locus_tag="L6J92_09725"
     CDS             complement(20400..21218)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1195: IclR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019435405.1"
                     /locus_tag="L6J92_RS09725"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="L6J92_09725"
                     /product="IclR family transcriptional regulator"
                     /protein_id="WP_195889494.1"
                     /transl_table=11
                     /translation="MNENRAATSPEASRPPLQTADRLLGVLQAFDRERPEWGVSEVAKE
                     FGLDKSVAQRLLAALAHRGFLVSDPRSRRYRLGPAVWHLALGWERDGGLARLVQPALRG
                     LSAESGVTTLFALPDGIHMRCVAFAEGAEGPLRVDGLSGELYPAHAGATSRAYFGMLGP
                     RDRAALLYSRPMARFSERTVVDPALLEERFAEVRRDGHAYSEGEYDPETAALAAPVAVG
                     RRAVGTLSLVAAADALRPRRGELVAPLLRTAAELGRLLTPAARPRPASRG"
     misc_feature    complement(21201..21217)
                     /note="TFBS match to GnfM, Regulator of nitrogen-fixation
                     genes, confidence: medium, score: 21.64"
                     /tool="antismash"
     misc_feature    complement(21268..21282)
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence: weak,
                     score: 16.62"
                     /tool="antismash"
     misc_feature    21269..21283
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence: weak,
                     score: 16.0"
                     /tool="antismash"
     gene            21530..>22480
                     /locus_tag="L6J92_RS09730"
                     /old_locus_tag="L6J92_09730"
                     /pseudo=""
     CDS             21530..>22480
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016905923.1"
                     /locus_tag="L6J92_RS09730"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /old_locus_tag="L6J92_09730"
                     /product="DUF1177 domain-containing protein"
                     /pseudo=""
                     /transl_table=11
                     /translation="MLKHVLDVIDLLDRPQTSGELLADHLRSVLADATDPATTSPTPPT
                     IEVRTVTGDRGSTDFVKVTVPGRGGRLSGGDAPTLGILGRLGGVGARPERIGLVSDADG
                     AVAALAAAAKLVDMHARGDVLDGDVILSTHVCGWAPTRPHDPVPFMDSPVDIALCNREE
                     VSDAMDAIVSIDTTKGNRLLNHRGIALSPTIRQGWVLRVSEDLLSVLETVTGEPARVIP
                     VTTQDISPYGNDVHHINSLLQPSVATDAPVVGLAITAGTAVAGCATGASHEPDIAAAAR
                     FAVETAKDFGRGAAHFYDRAEADRLIELYGRMTRLQ"
ORIGIN
        1 cctcgtgatc aacctcaagg cgcgccacta cgaggtcgac gccgcccacg acggggccac
       61 cgccctccag ctggccgccg cccgccagcc cgacgtggtg gtgctggacc tgggcctgcc
      121 ggacatggac ggcgtcgagg tcatcagagg cctgcgcggc tggacccggg tgccgatcct
      181 ggtgctgtcc gcccggcact cctccgacga gaaggtcgag gcgctggacg ccggcgccga
      241 cgactacgtc accaagccct tcggcatgga cgagctgctg gcccggctga gggccgccgt
      301 tcgccgctcc gagccggtcc ccggcggcga ggacgacgtg atcgtggaca ccgcggagtt
      361 caccgtcgac ctggccgcga agaaggtcca ccgcgacggg cgggacgtac gcctgacgcc
      421 caccgagtgg cacctgctgg aggtgctggt gcgcaacacc gggcgcctgg tcagccagaa
      481 gcagctgctg caggaggtgt gggggccttc gtacgggacg gagacgaact acctgcgggt
      541 ctacatggcc cagctgcgcc gcaagctgga ggcggacccc gcgcaccccc ggcacttcgt
      601 caccgagccg ggcatggggt accgcttcga gaagtgaggg gcggggccgg ggaagcggaa
      661 agtgagcctc gccatcccgc cccgagcggg tgcgtggctg tcggcgggcc ccggtacgct
      721 tcagatatga gtgctgctcc gcgttccgac aagccggtgg gccggttccg gcgcatgttc
      781 gaccggctct cctcgtccca ggaggacctg gagtcggagg aactgcgcga ggacacggac
      841 accaccggct gcacccgcat cggggactgc caggaccggc aggtcgtctc ggtaactggt
      901 accttgcgca cggtcaccca gcggccacgt gccggcgtcc cggccctgga ggccgagctg
      961 ttcgacgggt ccgccgccct ggacgtggtg tggctgggca gacgctccat cgtgggcata
     1021 gagccggggc gcaagctcat cgcatcgggc cgggtctcga tgagccacgg ccgccgggtg
     1081 ctcttcaacc cgaaatacga actgagaccc ctcggacggg agtagccggt gacgtcgctc
     1141 gacaagccga ccgaagacac gacagaggcc gacgactccc gggcggtgac ggaggccgcg
     1201 ttgttcgagg cgttcggcgg cgtgcggggc atgatcgaga cggtgctccc gggcctgctc
     1261 ttcgtcacca tcttcacgct caacaacgac ctgcacatgt cggcgatcgc ggccctggcc
     1321 gtgtcgttgg tgctggtcgt ggtccggctg gtgatgaagg acaccgtcaa gcacgcgttc
     1381 agcggggtct tcggcgtcgc cttcggcgtg gtcttcgcga tgatgaccga caacgccaag
     1441 aacttctacc tgccgggcat gctgtacacc ctgggcctgg ccctcgccta catcgtcacc
     1501 tcgctggccg gggtgccgct gatcggcctg atcctcggtc cggtcttcaa ggagaacctc
     1561 tcctggcgca cccgcaaccc gggccgcaag aaggcgtaca cgaaggccag ctacgcctgg
     1621 ggcctcatcc tgctcgccaa gtccgcgatc ctcttcccgc tgtactggtt cgcggacacc
     1681 gagcagctcg gctgggtcct ggtcaccctg aagatcccgc ccttcctgct cgccgtgtgg
     1741 ctgacctggg tcttcctggc caaggcaccg gcacccatcg acgtgttcgc ggagatggag
     1801 gcggcggagg aggccgagaa ggcggagaag gccgggcggg aacggcgcga gcaggaggcc
     1861 gacggcaccc tgccggggcc gccgtccggg gccgacggag ccgacgtgga aggcgccgac
     1921 ctgcgcggcg gcaggcaccg caaggcctga ccggcaggac gaccaagtcg accaaggcga
     1981 ccaggtcaac caaggcgacc aggtcaacca aggcgaccag gtcaaccaag gcgaccaggt
     2041 caaacaaggc gatacggcgg tggggcgccc ggagatctcc gggcgcccca ccgccgtatc
     2101 gccttgccgg gacgtactgg cccgccgtac cggccccctg ggccgccccg cctgggccgt
     2161 gccgtctcgg ctcagaccgt gccgtccggc cgccgccgcg ccgacagcag gtcctccagc
     2221 tgttcctcac gggcctgcgc cgcgacgaac agcagttcgt caccggcctc cagcgagtcc
     2281 tcccgcgacg gcgtcagcac ccgggtgcca cggatgatcg tcaccaggga cgtgtcctcg
     2341 ggccactgga cgtcgccgac ctgggtaccg gccagcgccg actcctccgg cagcgtcagc
     2401 tcgaccaggt tggcgtcgcc gtggctgaag cgcagcagcc ggaccaggtc gccgacgctc
     2461 accgcctcct ccaccagggc cgacatcaga cgcggggtgg agacggcgac gtccacgccc
     2521 caggactcgt tgaagagcca ctcgttcttc gggttgttca cccgggcgac gacccgcggg
     2581 acgccgtact ccgtcttggc cagcagcgac acgacgaggt tgaccttgtc gtcgcccgtc
     2641 gcggcgatca cgacgttgca gcgctgcagc gccgcctcgt ccagggacgt gatctcgcac
     2701 gcgtcggcga gcagccactc cgccatcggg acccgctcga ccgagatggc ggtcggcgcc
     2761 ttgtcgatga gcaggacctc gtggccgttc tccagcagct cgcccgcgat cgaacggccg
     2821 accgcgccgg caccggcaat ggcgaccctc atcagtgacc gccctcctct tcgggaccct
     2881 tggcgaacgc cgcctcgacc ttgtggacct cgtcggtgcg catcatcacg tgcaccaggt
     2941 cgccctcctg cagcaccgtc tgcgaggtgg gcaggatcgc ctccccgagc cgggtgacga
     3001 aggcgacccg cacgcccgtc tcctcctgga gccggctgat cttgtgaccg acccagtacg
     3061 acgacgtgtg cacctcggcg agctggacgc cgcccgtggg atcgcgccac agcggctcgg
     3121 cgcccgaggg gagcagccgg cgcagcatct ggtcggccgt ccagcggacg gtggccacgg
     3181 tcgggatgcc caaacgctgg tagacctcgg cgcggcgggg gtcgtagatg cgggcggcga
     3241 cgttctcgac gccgaacatc tcgcgggcca cgcgggcggc gatgatgttc gagttgtccc
     3301 cgctggacac ggcggcgaag gcgccggcgt cctcgatgcc cgcctcgcgc agggtgtcct
     3361 ggtcgaagcc gatgccggtg acccggcgac cgccgaacga ggaaccgagg cgccggaagg
     3421 cggtggggtc ctggtcgatc acggcgaccg tgtgcccctg ctgttccagg ttctgggcga
     3481 gagcggagcc gacccgcccg cagcccatga tgacaatgtg cacggcttac accactcttc
     3541 ttctcagccc actgagcggg gtgaacgtcc cgttcatctt cctctttcgg ctcgacgggc
     3601 acacacatgc ggccccgctg ggagccgcat gtcaccatca tgcccgcccg ccgcggcacg
     3661 cccccgccgg ggtgggcggg cagacggggc acggaggcgg gccggacgag acggaagcgg
     3721 ggcgagaggt gttcggcgcc gtgtggttcc tgcttcggtc tacgcgtcac ggacggcgaa
     3781 gttcgtcccc cacgtgcacg gagggccgcc cgtgccagcc ctcagccgga gttccccgcc
     3841 ggccgatgct gcgcacgctg gcgaaggtca ggattccgag gccgacgagc gtgacgccgc
     3901 cgccgatcag ctccgcggac aggtgcatgg ggtctccctc agcgcgacgg acagcggttc
     3961 ggccggtgtt ggtcatatag gcatgcgaac cccgccacca gcgcaatccg cagccgcccc
     4021 gccccccgag ttcacccgta gggcagacgg caggcggatc gggggtggcg ggtgggcggc
     4081 cgctcgttcg aacgcttacg atcctctgtt gtgtccaaac tgaccgacgt gcccaagcgg
     4141 atcctgatcg ggcgcgccct gcgcagcgac cggctgggcg agacgctgct gccgaagcgc
     4201 atcgctctcc ccgtcttcgc gtccgacccg ttgtcctcgg tggcgtacgc gcccggcgag
     4261 gtcctgctgg tcctgtccat cgcgggcgtg tcggcgtacc acttcagtcc ctggatcgcg
     4321 gtcgcggtcg tcgtcctgat gttcaccgtc gtcgcctcct accggcagaa cgtgcacgcc
     4381 tacccgagcg gcggcggcga ctacgaggtg gccaccacca acctgggccc gaaggccggt
     4441 ctgaccgtgg ccagcgccct gctggtggac tacgtcctga cggtcgccgt ctccatctcc
     4501 tccggcatcg agaacctggg ctcggccatc cccttcgtcg tcgagcacaa ggtcctgtgc
     4561 gcggtcgccg tgatcctgct gctgacgctg atgaacctgc gcggggtcag ggagtcgggc
     4621 accctcttcg cgattccgac gtacgtcttc gtcgccggcg tcttcatcat gatcgtgtgg
     4681 ggcgcgttcc gcggcctggt cctgggggac accatgcgct ccccgacggc ggactacgag
     4741 atcaaaccgg agcacggcgg cctggccggc ttcgccctgg tcttcctcct cctgcgcgcc
     4801 ttctcctccg gctgcgccgc gctcaccggc gtcgaggcca tctccaacgg cgtcccggcc
     4861 ttccgcaagc ccaagtcgaa gaacgcgggc aacaccctgg ccatgatggg cctgctcgcc
     4921 gtgaccatgt tctgcggcat catcgcgctc gcctccgcga cggacgtccg catgtcggag
     4981 aacccggcca ccgacctctt ccacaacggc gtcgcggtcg gcgcggacta cgtccagcac
     5041 ccggtgatct cgcaggtcgc cgaggcggtc ttcggcgagg gcagcttcct gttcgtcgtc
     5101 ctcgccgccg ccaccgcgct cgtcctcttc ctggccgcga acaccgcgta caacggcttc
     5161 ccgctgctcg gctcgatcct cgcccaggac cgctacctgc cccggcagct gcacacccgc
     5221 ggcgaccgcc tggccttctc caacggcatc gtgctcctcg ccggggccgc catgctcctg
     5281 gtcgtcgtct acggcgccga ctccacccgg ctgatccagc tctacatcgt cggcgtgttc
     5341 gtgtccttca cgctcagcca gatcggcatg gtccgccact ggaaccggaa cctgaccggc
     5401 gaacgcgacc aggccaggcg ccgccacatg atccgctccc gggcgatcaa cgccttcggc
     5461 gccttcttca ccggcctggt gctggtcgtc gtcctggcca ccaagttcac ccacggtgcc
     5521 tgggtcgccc tgctcggcat gtgcatcttc ttcgcgacga tgacggcgat ccggggccac
     5581 tacgaccgcg tcgccgagga gatcgcggcc cccgaggacc ccgaggaggc acagagcgac
     5641 gacatggtcc gcccctcccg cgtccactcg gtcgtcctga tctccaagat ccaccgcccc
     5701 gcgctccgcg ccctcgccta cgccaagctc atgcgctccg acagcctgga ggcgctcagc
     5761 gtcaacgtcg acccggccga gacgaaggcc ctgcgcgagg agtgggagcg ccgcggcatc
     5821 gccgtacccc tgaaggtcct ggactcgccg taccgcgaga tcacgcggcc ggtcatcgag
     5881 tacgtcaagg gcctgcgcaa ggagtccccg cgcgacgccg tctccgtgat catccccgag
     5941 tacgtggtcg gccactggta cgagcacctg ctgcacaacc agagcgcgct gcgcctcaag
     6001 ggccgcctgc tgttcacccc cggcgtcatg gtcacgtccg tcccctacca gctggagtcc
     6061 tccgaggcgg ccaggcgccg ggcccgcaga cgtcagaact ggagcgcccc cggcgcggtc
     6121 cgccggggcc ccgcccacca cgaccgtacg aaggactcgt cctcgtccac ctcttcgtcc
     6181 acgtagactg gacggctgtt gtcctcagcc gtcacccccg ttctctggag tcaccccgcc
     6241 atgcaggcag aaccgacgaa tacgcaggcg gagacgcgag cgacgccgca gccggccgag
     6301 cgaccggcct cgctggtggg cgaggagtac gaggtcgagg tcgggcccgt cgcccacggc
     6361 ggccactgcg tcgcccgcac gtccgagggc caggtgctgt tcgtccggca cacgttgccc
     6421 ggcgagcgcg tcgtggcccg ggtgacggag ggcgaggagg gcgcccgctt cctgcgtgcc
     6481 gacgcggtgg agatcctgga cgcctccaag gaccgcatcg aggcgccctg cccgttcgcc
     6541 ggccccgggc gctgcggcgg ctgcgactgg cagcacgcca agccgggcgc ccagcgccgc
     6601 ctcaagggcg aggtcgtcgc cgagcagctc cagcgcctcg cgggcctcac cccggaggag
     6661 gccggctggg acggcacggt gatgccggcc gagggcgaca agctgcccgc cgggcaggtc
     6721 ccttcctggc gcacccgcgt ccagtacgcc gtggacgcgg acggccgccc cggcctgcgc
     6781 cgccaccgct cccacgaggt cgaacccatc gaccactgcc tcatcgcggc ggacggcgtc
     6841 agcgagctgg gcgtcgagca gcgcgactgg cccggcatgg cgacggtcga ggcgatcgcg
     6901 gccaccggct cccaggaccg ccaggtcatc ctcacccccc gccccggggc ccgccttccc
     6961 ctcgtcgaac tggaccgccc ggtctcggtc atgcgcgtcg acgagaagga cggcggcgtc
     7021 caccgcgtcc acggccgctc cttcgtccgc gagcgcgccg acggccgcac gtaccgggtc
     7081 ggctccggcg gcttctggca ggtccacccg aagtcggccg acaccctggt gacggcggtc
     7141 atgcagggcc tcctgccccg caagggcgac atggccctgg acctctactg cggcgtcggc
     7201 ctcttcgccg gcgcgctggc cgaccgcgtc ggcgaccagg gcgcggtcct cggcatcgag
     7261 tccggcaagc gcgccgtcga ggacgcccgc cacaacctcg ccggcttcga ccgggtcagg
     7321 gtggaacagg gcaaggtcga gtcggtcctg ccccgcacgg gcatctccga ggtcgacctc
     7381 gtcgtcctcg acccgccccg cgcgggcgcc ggccgcaaga cggtccagca cctcacgacc
     7441 ctctccgccc gccgcatcgc ctacgtcgcc tgcgacccgg ccgccctggc gcgtgacctg
     7501 gcgtacttcc gggacggggg gtaccgggtg cggacactgc gggtgttcga tctgtttccg
     7561 atgacgcatc acgtggagtg cgtggcgatt cttgagcctg cgggcaaggg ggcctgacct
     7621 gcgctctcat ttggacctca cgtttccagg agcgcgactc gaatgtgcca gccgtgatac
     7681 cggtcaggta tcatggctgt atggcgatga cactccggct tcccgacgac cttgacgcga
     7741 agctcaccga gcgggctcgt cgggagggcc gcagcaagca ggaacttgcc attgaggcca
     7801 tccgtgacgc gcagaaccgg gccgagctga aggtcgatga tgttctggcc gagctgttgg
     7861 acagcgatgc ggagattctg gactacctga agtgacgaac gtgcgctacg ttcagatcga
     7921 cgagatcctg gccatcgctc gcacggtcaa cggtaccgag cacagcgtgc gtgacatggg
     7981 tcttctggtg tcggcgatcg agcggccccg gacgaacgtg ttcggtgccg agttgtatcc
     8041 cacgttgcac gagaaggctg cggcgctgct gcactccgtt gcccgcaatc acgcgttgat
     8101 cgacggcaac aagcgcaccg cctggctcgc cacgcgtgtc ttcctgcggt tcaacggcgt
     8161 cagcgccagt accctcccgc cacacgtctc cattgtcggc ccgttcgtcg aggacgtcgc
     8221 gcaggacaac atcgatgtac cggtcattgc caagcgtctg gcggcctggt tcgccgtttc
     8281 ctgacgttcg acgacgcagg gcaggacacg cgcgtgccct gcccacgagc tgtcgaacgc
     8341 cacccgcaca tggccgcatt ggctggttcg ggagtatcgg gctgggccaa tcgaagggct
     8401 tcgacgcccc gcactgggtc ctctgccacg gcttcacgta cccggctccg tcgtgatcga
     8461 cgcctcctgg gccaaggaac tgcacggaag agtgcggcac caactcccgg acggacaagg
     8521 cgatcgaagc tgtttcccgt ttccttttcc gacagcgggg tgcggcaagc ccgtgtggga
     8581 cagacgcccc cccgggccgg tgctcgtgtt tccggcggac ggctgggtcg ccttcgtttc
     8641 aatggatgcg agtgggcgct cgggtgcctg agtcgaggtg cggtcaattc ggcgccatgg
     8701 ctccgcacga tgacccgaag gaaagcacga tggggccttc gcggcggccg cccacgcggc
     8761 cgggcccgcg gcacagctga cgagccgctc tgccatcagg aacgcagccg tgcttcctgg
     8821 ggccgctgcg ccgaacaggc ctcaccgcgg aaagcgacgg tgtcgccgcg gtttgcgggc
     8881 tgccgaggac gatcaccatc cacgtgccgc acaccgatgg tcctctccgg ctggccgggc
     8941 aggtacgggt gcgggcggtg atggacctgc gatatgccgt gctcgccgcc gatctgcctg
     9001 gtcggcacgc tggtcggagt cggtgcgttc gccgacgcgg ccatcggcga gagggcgtgg
     9061 ctggagttga tgcacttcag cgtcatgcat tttccggctc ttatggacgc tgacttcgtc
     9121 accgaacgca ccgtcgcgcc cactccgtcc atggggacgc cctgctgttt gtcgaccgtg
     9181 acgttcgttt gacgctcgtc ctgatggggg gtcaggtgtg gtgcatcgct gctcaggtgg
     9241 tctgatggcg aaggccgtgt ggcaggggtg ccggaatttc catggtctca agtgtctgtg
     9301 gtcgtggagg tgcctctcga cgttcgggtg gggtgtggcg gtggaccatc tacggtgcgc
     9361 ggggtcaccg gattgtccgg cgatcccgcg ctgcgttgcg cgtcctcgct gcgggtcggt
     9421 ggaccacggt ttcgggctcg tgcctctggc ggcggggcgt gcggggacgc gccggaggtc
     9481 tcggcggcgt gctgcgcagt cgtccaggtt gtccttgtag agctgtgctg ggagtttggc
     9541 ccacaccctg gcctcgggcc actcgccgaa ccggtgtaag cggggtcacg cccgacaggc
     9601 tgaagtccgg ggcaactggt tccaggtaca gcccgaggtg gctaggacgg tggctgtggc
     9661 caacacttcg cgggcccctt gccgacgatg gcctccgccc tgcgggcgaa ctggcgccga
     9721 cggcaccgcc cgctgattca cggtccacag gtcttcggat gccatccgct cgacatgtgc
     9781 agcagtaccc cccccaggct gccgcaagat catgccaact gacatgacga ggcgtcggag
     9841 tgcgcgatgt cgaccggttt cgaccacacc tgatcgccgg gcggggtcgg ccgaggttac
     9901 ccgtgcgttc cgcacatcgc agtggtgaca ccggtgactg tcccggactc ggcggcccgt
     9961 gacagcgtct cctcggcacc gacctgcgga gggagaaggc gtgaacaagg gctacgccgt
    10021 gtactgcgac gcggatccgt acttctacga cgccccgcac cgcacggccc ccggcaccgc
    10081 ggcggcgggc acccgctact cggcggccac cgagcccgtc ccggccggct ggcggcgcgg
    10141 cgagagcggc gactggctcg cgctgaggcc gctcgacgcc gacctgcccg ctcagggctg
    10201 gaagatccac gtctccgcct gcctggacaa cgccgaatcg gttctggagc gcgtgaagcg
    10261 ccactgcgtc gagcacggcg tcgccttcaa gttcgttccg agccgctacc tgctgcacca
    10321 gcgcaacgcc aagtacgccg accggtcggg cagtggcaag ttcatcacgg tgtacccggc
    10381 ggacgaggaa cacttcgagc gcctcgcggg cgagctgacc gccctgctgg ccggcgagcc
    10441 cggaccgcac atcctgagcg acctccgcct cggcgacggc ccggtgcacg tccggtacgg
    10501 cagcttcacg cgccgcgact gctacgacga gaacggcgac ctgcggccgg cggtcgcggg
    10561 cccggacggc gtgctcgtac ccgacccgcg tggtccggtg ttccgggtgc ccgactgggt
    10621 gagcgtgccg gccttcctgc ggccccacct ggaggcccgg gccacgacga ccctgaccga
    10681 cgtcccgtac accgtcgaga ccgcgctcca tttctccaac ggcggcggcg tctaccgggc
    10741 gcgcgacacc cgcacgggcg aaccggtggt cctcaaggag ggacgcccgc acgccgggct
    10801 ggcagccgac ggagcggacg cggtgacccg cctggagcgc gaacgccggg ccctggagcg
    10861 gctgtccggt ctggactgca cccccgaggt gcgggacgcc ttcaccgtcg gcgagcacca
    10921 cttcctggtc ctcgaacacc tcgacggcaa gccgctcaac accttcttcg cccgccgcca
    10981 cccgctcatc gaggccgacc ccggtgagga gcggctcgcc gagtacaccg cgtgggcgct
    11041 cgacatccac gcgcaggtcg aagaggccgt tgcccaagtg cacgggcggg gcgtggtctt
    11101 caacgatctg cacctgttca acatcatggt ccgcgacgac gggcgggtgg ccctgctgga
    11161 cttcgaggcc gcccggcacg cggaggagcc ggggcggcag accgtcgccc atccggggtt
    11221 cgtggccccg tccgaccggc ggggcgaggc cgtggaccgg tacgcgctgg cctgtctgcg
    11281 cctcgccctg ttcctgccgc tgacgagcct gctggcactg gaccggcgca aggcggagca
    11341 cctcgccgac gtggtggcgc ggcagttccc cgtcccgcgg gccttcctgg acgcggcggt
    11401 cgccgagatc accggtacgc cggtccgggc tgtggcgcga gcagccggcg gcgggttcgt
    11461 cccggtcgag ccgggcgact ggccccacag ccgggactcc atgacggcgg ccgtccgcgc
    11521 ctcggcgacc ccgtcccgcg acgaccggct cttccccggc gacgtcgccc agttcgccac
    11581 cgcgggcggc ggccttgcct tcggccacgg ggcggccggc gtgctgtacg ccctcgccga
    11641 gagcggcgcg ggacgtgacg aggccgggga gcagtggctg ctggagcgaa cgaaggagcc
    11701 acccgcgggc atgccgccgg gcttccacga cgggatcgcc ggcaccgcct ggaccctgga
    11761 ccgcctcgga caccgggcgc gcgccctcga cctgaccggc agactcctcg aacaccccct
    11821 ggagggcctc gcccccgacc tgcacagcgg cacggccggc atcggcctgg cgctggactc
    11881 cctggccgcg tccacgggag acgcggccct gcgtgccgcc gccctgcggt gcgccgaact
    11941 gagcgcccac ggcctcccgg ccggcgccgt ggtccgggca tccggccgca gaccccgggc
    12001 cgggttgctg cacggcgcga cgggccgcgc cctgctcttc ctgcgcctgt acgagcgcac
    12061 cggcgacacc gccctgctgg atctcgccgg cactgcgctg cgccaggacc tcgcgtcctg
    12121 cgtgcggggc gcggggggag ccctccaggt ggacgaggga tggcgcacca tgccgtatct
    12181 cggtgccggc agtgtgggca tcggcatggt cctcgacgac tacctggcgc accgcgccga
    12241 cgaggagttc gagcaggcgc ggaccgagat cgtgcgcgcg gcgcaggcca tgttctacgc
    12301 gcagcccggt ctctaccggg gcgtcgccgg catggtgctg tacctcggcc ggaccacggc
    12361 gcccggcccg ggcaccggac cggaggccgt ccggcgccag atcgacgcgc tggcctggca
    12421 cgccatgtcc taccgcggcc ggctggcctt ccccggcgag cagatgatgc gcctgtcgat
    12481 ggacctgtcc accgggacgg ccggctgcct gctggccctc gcgtccgtgc acggcgaccg
    12541 gtccgccggt ctgccgttcc tccccccgcc gcggtccgta ccgcggcccc atgagccggt
    12601 cccacccggg accgtgaagg aagcacccgt agtcgtcacg aagggatgag cacatgaacc
    12661 tgttcgacct gcagtcgctg gagaccccga aggaagaggc catgggggac gtcgagaccg
    12721 gcagccgcgc cagcctgctg ctctgcggcg acagcagcct cagcgtcacg acctgtaact
    12781 gacgcctgtg cggtccgcgg cggggcaccg ccgcggaccg cacggtcggc gccccggcct
    12841 catggccggg gcgccggtgc ggcgcctcga cgccgccgtg tgcagagccg accgggagga
    12901 gtagcggctg gtggacacca ctgcggtccg gcgacggcgc gggcgcgcgg gacccggccg
    12961 cgccggcgcc gatcccggcc ggatccccga actgctggtg ctggtctgct cggtagcggc
    13021 ttcggccgtc gcggtcgcgc agcccctggt cctcggccgt gcgctggacc tcctgctgcg
    13081 ggacggcgac gtcgggccgt ggctcgcggc gagcgtggcc ctgctcgtcg gtgaaatcgt
    13141 cctcgacgcg ctgacggcgc tgttcaccgg ccgctgcacc gcccgctgga cggcgtcggt
    13201 ccgctcccga gccctcaccg gcctgttgcg cgccgtacca ggagcgacgc gcccgtactc
    13261 cgcgggggac gtggcgacgc gcctcacgct caacgcctcc gacgcgggcg gcgtcccggc
    13321 ggcccgcgcc gcgctggccg cctcgctgat caccccggtc ggcgcactcc tcgccctgtt
    13381 cctcgtcgac gtgtgggccg ccgcctgcgt ggtcgccggg ctgcccgtac tggtcctggt
    13441 gctgcgggcg ttcgcacgcg acacgggggc gtcggtgcgc gcctaccagc acgtgcagtc
    13501 ggacatcgcg ggccgcctgc tggaggccat ggagggcgcg gagaccatca cggccgcggg
    13561 gacgacaccc cgtgaacgcg agcgtgtgct gaggcctttg gcggagctcg gtgcgctggg
    13621 cgaacgcatg tgggtcctgc acgggcgggc gctggccacc ggaggcgtcc tcgtgccgct
    13681 gctgacggtg gcggccacgg cggtcggcgg actgcggctg gccgcgggag ccctgagcgt
    13741 cggcgaactg ctcgcggtgt gccggtacgc gcaactggcc gcggggttcg gcggcgcggc
    13801 cacgacgttg ggcgcgctgg tacggggccg tacggcgcgg gagcgcaccg cggccctgga
    13861 tcggctgccc gccctgcggc acgggcggcg caccctgccc ccgggcggcc cgggtgtcct
    13921 tgagctgcgc ggggtgcgcg ttctgcggga cggggccgag gtgctgcggg cggacggcgt
    13981 ggtggtgccg ggcggggcga ccgccgcggt cgtgggccgc agcggcgccg gcaagtcggc
    14041 gctggccgct gtggccggcc ggctggtcga ccccgacgcg ggagaggtcc tcctggacgg
    14101 cgtaccgctg gcctctctga cgcgccggag tctgcgggcc gaggtcggtt tcgccttcgc
    14161 gcgtccggtt ctcggcgccg gcaccgtgga gcaggcggtc gcggccgggg tgcgcgccgc
    14221 gacgcccgac cgggtccggg aggcggtgcg cgccgcgggc gccgacgcct tcgtgcggcg
    14281 ccttccccgg acgtacgaca cgccgctcgg cgacgtccct ctgtccggtg gtgaacacca
    14341 acgcctggga ctggcgcggg cgttcgctca cgcggggcgg ctgctcgtga tggacgacgc
    14401 gacctccagc ctcgacaccg ccaccgaaca cgccgtggac cgggcgatgc ggcgcatgct
    14461 cgacgggacc acccgcctgg tcgtggcaca ccgcccgtcg gtcgcggccc gggcagactt
    14521 ggtggtctgg ctggaggacg ggcgggtacg ggcggtcggt ccccaccggc acctgtggga
    14581 gacggccgcc taccgggccg tgttcgccac ggagacggag cccggggcgg ggcaggctcg
    14641 tgcagaagag accggtgtcg cgccgcccgc gggcgaccgg gccgcctccc tccacggcga
    14701 ggtacggccg tgacctctcc cggagccggt acggcgaccc gggagcgcgg tgcgctgcgc
    14761 cgcgtcgcgc cgcccgcccg ccggttcctg gccgaccgca agggcgtcct cgcccggctc
    14821 ggcgcgtggt cggtggccga gtcggctcag accttcctgg gcgggtacgg cgtcgcgcag
    14881 gccgtcgacc gggggttcct ggccggtgac acggccgcgg ggctcggctg gctcggtgtc
    14941 gccgccgtcg ccgtactgct cggggcgccc gtggtcaccg gcgtcttcgc ccaactggcc
    15001 cgcctcaccg aaccgttgcg ggacgcgctg gtatgcaggg cggtgacccg gtccctggcg
    15061 gaggcgtcgg cccgccccgg tggcggggac cgcgccgccg tctcgcggct cacgaaccag
    15121 gtcgagatcg tgcgggacag cttcgccgga ctcgtgttga ccctgcggtc gttcgtcttc
    15181 accgccgcgg gcgcgctgct ggggctgttc accctggatc cggcgctgct ggtggtcgtc
    15241 gtgccgccgc tggccggggg cctggcgctg ttcctggtca cgctgcggcc gatgtcggcg
    15301 gcgcagcgcc gggccctcgc cgccgacgag gcgctgggcg atcacgcgag ccgcacccgg
    15361 ggggcgctgc gcgacatcac cgcctgcggg acgcgggagg atgccgcccg gcgcggggag
    15421 cgtctggtcg aggacgccgc cgtctgcgcg cgggttctcg cccgctgggc ggcggtgcgc
    15481 accctggccc tcggggtggc gggccaactg cccttcctgc tcctgttgct ggcggtgccg
    15541 tggttgcgcg cccggggtgt gggcaccggc gcgctgctgg gtgccttcac ctacctcgcc
    15601 cagtctctgc tgcccgcgct gcacaccctc atgacggcga tcggagccgc ggggacacgg
    15661 ctgctggtcg tcctggaccg catcaccggc acggtgcccc cggtcaccgc accgcacgca
    15721 cccgcttcgg agacggcccc gcaggcggta tccccaccgc caccgctccg gcggtcggcg
    15781 agtacgccga cgcccgcggt ggaactgcgg tcggtcacgc tctcctacgg cgcgcgcgcc
    15841 gagccggtcc tcgactccct cgacctgcgc gtcgaggacg gcgagcacct ggccgtcgtc
    15901 ggccccagcg gcatcggcaa gtcgacactg gcccgcgtcg tcgccgggac actggcgccc
    15961 ggcggcggca cggtcgaggt cgccggccgc ccggtcaccg gccgcgaccc ggccgaactc
    16021 ggcgcgctgc gcgccctgtt gcctcagcag gcgtacgtgt tcacctcgac ggtgcgggac
    16081 aacctcacct acctgtgccc cgacgcccgc acggccgaac tccgggccgc cgtgcgggaa
    16141 gtcggcgcag acggcctcgt cgcgcggctg ggcgggctcg acgcgccgct cgtgcccgga
    16201 gatttgtccc agggcgagcg gcaactcctc gtgctggtgc gggcccatct ctccccggcg
    16261 cggttgctcc tgctcgacga ggcgacgtgc cacctcgacg cggctgccga ggcccgggcc
    16321 gaggaggcgc tcgcccggcg tcccggtgcg ctgctcgtcg tggcgcaccg catgtcgtcg
    16381 gcgctgcggg cggaccgcgt cgtggtcctg gacggcgtcg gcgcggtgtg cggcacgcac
    16441 ggggacctcc tcggccgttc accgctctac cgcgacctgg tggggtactg gggcgggacc
    16501 cgggagtgaa ccggcgggcg cccgcgcctc cttctcacat ccagccggct ctctggacga
    16561 tgcggatcgc gtccacccgg ttgcgggcgc cgaccttgcg tatcgcgctg gccaggtagt
    16621 ttcggacggt tccccgcgac aggtgcaggg ctgccgctat ctccgcgacg ggggagccct
    16681 gggccgcctg agagacgacg ctcagttcac gagccgtcag cggcgtccgt gacgcgtcga
    16741 gcagggcgac ggccagcctc tcgtcgagga accgttcccc cttggcgacc gtgcgcacgg
    16801 cggtgatcag gcgctcggac ggggcgtcct tggcgacgaa gccgagcgct cccgcgtcga
    16861 acgcccggcg cagcacgccc ggccgttccg gtgccgcgag caccaccagc cgggttccgc
    16921 acctttccca gtacggggtg tgacagagcg tttccagccc ctccagacac tccccgtcca
    16981 cgacgcacac gtccgcggga aagtcgtcgt cggactcctc gccccgggag gacatggacg
    17041 tgacctcgag tctgtcggcg gacaggagca gttgcgccag tgccgaccgc agcagcagcg
    17101 cgtcgtgcac cacgagaacc cggaccatgt gcgaccccca caatctcccg gcggcctcgc
    17161 ggaccgccgg gctcgtcccc caatgtccca agcgtctgcc cccggggccc gtcggagaag
    17221 cacggcgtgc cgccgggcgc gggggcggcg tcgtcaacgc gccgttctgg acggcgtcgc
    17281 acggtgcgga ggggccgcgc gagcaggccg gaacacggcc ccggcgcgca cgagccggtg
    17341 gggcgctacc ggcagcgtcg gtgccctgat ggccgctgac agcgggttct gtcggcgagg
    17401 cggcgtacag ggcccgggaa gcgggcccgg aggggccttt cctcgccggt ctccacaggc
    17461 cgaaaaccgt cgtggtgaaa gtggcccgaa ggtacacgtc cttcacaggt cggacttgcc
    17521 ctgcgcgact ggtccctgtt tcctgcgcac cgcggcccgg gccacgctgc ccacgatcgt
    17581 gcgcaccggc ccggacgctc cccgcgcccg tgcctgcccg ggcgaatttc cgccgcccgg
    17641 ggccgtggtc gaccggccgt tcctcgacgg tcgccgacgg gaggcagacg cgccccggcg
    17701 tcggtggtcc tcctccgcag agtgcgcgtg ggtccgaccg gcggcggact gatcgatgag
    17761 accgttccgg agggtcgggt caccagggca caacaccgtt gtggtcgcac agttggccgg
    17821 tagggccgcc gtccggcagg gtcgccagcc gtatggcgac cgccgcgccc tcctcggagg
    17881 tctgagtccc gctgaacccg ttgagatcgg tggccacgta gccggggcag gcgctgttga
    17941 tcagaatgct gctgccgttc agttccttgg cgtactggat ggtgagggcg ttgaggtagg
    18001 tcttcgtcgg cgcgtacccc ccgctgatcc ccccgaggtc gacgccgggc gtggtctgca
    18061 gtgtcaggga gccaacgtga ctggactggt tgacgatccg cgggtgctcc gagcggcgca
    18121 gcagtggcag catcgcgttg gtgaccctga tgacgccgat gacgttggtc tccagcagca
    18181 gccgcacggt ctcggggtcg acggccgtgg gttcctccgg ccggccgcaa gcaacaccgg
    18241 cattgttgac cagtacgtcg agccgtcctg cccgctcctc gaacaggcgg accgcggcgg
    18301 tcacactctc gccgtcggtc acgtccaggg gtacgccgaa cgcgtcggct ccagccgcgc
    18361 gcaacttcgc cacggcgtcc tgccggcgtt gcgcgtcccg ggcgccgaca ccgacactcc
    18421 agcctcgcgc acccagcccg gccgcgatct cgtatccgat ccccttgttc gcgccggtaa
    18481 ccagcgcgat cgtcttctcg ctcatgacag cgagcatgct cgtgccgcgg ccggacacca
    18541 acaccatctc ggtgacgcgg cgatacccca ccggtattga tctgccgcct gctgccgtta
    18601 gcctgggccc gtggaactac gagagctgcg gtactttgtc gccgtcgccg aggaactgca
    18661 cttcggcaag gctgcccagc gtctcgggat ggcccagccg cccctgtccc gcgcgatcaa
    18721 ccggctagaa cagcggctcg gaaccgcact gctggaacgc accagccgca aggtcacgct
    18781 cacggtggcc ggaggcgtgc tgctggacga aggacgcgcg atcctcggcg cagtgaccgc
    18841 ggccgagcgg cgtacccgtc gagccgcgac agcacacccc ggaattgtcc tcgccgtgaa
    18901 gtccggcaca ggtggcgaac tgctgacgaa actgctcgac gcctacgccg ccgaatccgg
    18961 cgcagtcacc gtcgaactac tgctctgcga ggcacaccag caccagttgc tgctgcagga
    19021 cgggcaagcc gacgcagctc tgctgcacct gcccttcgac tcggcagccg ggctcgacac
    19081 cgaaaccctg tgcaccgagg gacaggtcgc gatcctgccg gcctcacacc cgctcgccag
    19141 ccgttctcac atccggatgg ccgacgtcac cacgctgccg gagctgccga tggcgcgctg
    19201 gcccgatccc agcggcagct acccggaggg accgggcgca gaggtacgga acctgacgca
    19261 gctcttccag ttggtcgcgc tcagccgtac caccgtggtc gttcccgagt cgtccggcgc
    19321 cgacctgcgc cgggacctcg ccgccgtacc ggtcctggac gctccacccg tgacaacggt
    19381 gatcgcctgg ccgccgcaca gccgccttcg tgcagtcgct gaactggtcc gcgtagcaac
    19441 acttctgtga acccggactg aaggagtgtc tcttcaacgg caccccccat tcccggcacg
    19501 gttccccggc ttccggtgcg cgagtcacca ggacggcatc accaggaacc ctcagggcga
    19561 gcagcggcgt gccgccgcag cccacaccgt cggggggcct gcgtctcgcc ggcgttcttc
    19621 tccgaggcgt cagcgcacgt cgaagcgggc ggagcgggtg agcagtgcgg agaggtcgct
    19681 gccgaccgcg gtctcccgcg ctccggcggc ccggtcgaag accaccgctc cggtcgtcgc
    19741 cccgcccagg gtgaggctgt cgccgtcgcg gcgcagccag gtgccctcgc ggagtgcggc
    19801 caccgggacg tcgttctcct ccaggaactg ctccagccgc tcggcacggg tctcgcccat
    19861 gtgcgaggag tccggcgagg cgtccaggta gtgcgggttg atctggaacg ggaccaggcc
    19921 gagcgcctcg aaggtgggcg gctggacgat cggcatgtcg ttggtggtgc gcagcgtcgg
    19981 gcaggccatg ttggtgccgg cgctggagcc cagatacggc gcgcccgcgg cgacgcgttc
    20041 gcgtgtcgcg gtcaccaggc cgtgggcgtg caggttcttc aggagccgga agctgttgcc
    20101 gcccccgacg aacaccgccc ccgcgtcccg gaccgcccgc gcggggtcgg cgtgggtgtg
    20161 tacgccggtc acacgcacgc ccagcggcga cagagcagcc cggaccttgg cggtgtaggc
    20221 gtcgtggtcg gcgagcgcgt acgggacgaa gaccaggtcg cgtacgtcgc cgagggtgtc
    20281 ggcgatctcg tccttcgcgt gctccaggta cccgtgtccg ggcgcggtgg aattcgagag
    20341 cagcagcagt ttcatggtcg tcctcgggtt gtcgacacgg atgccgtagg tgggcgcggt
    20401 cagcctcggg aggccgggcg cgggcgtgcc gcgggggtca gcagacgccc cagctcggcg
    20461 gcggtgcgca ggagaggggc gacgagttca ccgcgccggg ggcgcagggc gtcggccgcg
    20521 gcgacgagac tcagggtgcc caccgcccgt cggcccaccg cgacgggggc ggcgagtgcc
    20581 gcagtctccg gatcgtactc cccctcggag taggcgtgtc cgtcgcgtcg cacctccgcg
    20641 aaccgctctt cgaggagggc cgggtccacc acggtccgct cgctgaagcg ggccatcgga
    20701 cggctgtaga gcagggcggc gcggtccctc ggaccgagca tcccgaagta cgcccgggaa
    20761 gtggcgccgg cgtgcgccgg atacagctcc cccgacagcc cgtccacccg gagcggcccc
    20821 tcggcgccct cggcgaaggc cacgcaccgc atgtggatgc cgtcgggcag ggcgaacagc
    20881 gtggtcaccc cggactcggc gctcaggccc cgcagtgcgg gctgcaccag ccgggccagc
    20941 ccgccgtccc gctcccagcc gagcgccaga tgccatacgg cggggcccag gcggtagcgc
    21001 cgcgagcgcg ggtcggagac gaggaagccg cggtgcgcga gcgcggccag caggcgctgt
    21061 gccacggact tgtcgagccc gaactccttc gccacctcgg agacccccca ctccgggcgc
    21121 tcgcggtcga acgcctgcaa cacccccagc aggcggtccg cggtctgcag cggcggacgg
    21181 gacgcctccg gcgacgttgc tgcccgattc tcgttcatgg accgcagcgt aacgtttctc
    21241 ggatatcggg aaaatattgc gctcagagat tttccgcaga attctgaccc ccggtacccc
    21301 accgtctgcg cgtccggccc cggcgtccgc cccgacccgg acagcgcgcc ggcgccgcgt
    21361 cccgatggcc cacaggccac ctgcgcggtg gaccggaaac cccggagggg gagtgtgcga
    21421 cggcgctcat ccccgccctc cgagacctgc caccggcaca tcccgcacca ccgttccgcc
    21481 cggccgcccc cctttcgagg gcgggccggc ccccgtgaga ggcgctccct tgctcaagca
    21541 cgtgctcgac gtcatcgacc tcctggaccg tccgcagacc agcggcgaac tgctcgccga
    21601 ccacctccgg tccgtcctgg ccgacgccac cgaccccgcc accacctccc cgacgccccc
    21661 caccatcgag gtacgcactg tcacgggcga ccggggcagc accgacttcg tgaaggtcac
    21721 cgttcccgga cgcggcgggc gcctttccgg cggggacgcc ccgaccctgg gcatcctggg
    21781 gaggctcggc ggggtgggcg cacggcccga gcgcatcggc ctggtctccg acgccgacgg
    21841 agcggtcgcc gcgctcgccg ccgcagccaa gctcgtcgac atgcacgccc gcggcgacgt
    21901 cctggacggg gatgtgatcc tctcgaccca cgtctgcggc tgggccccca cccgcccgca
    21961 cgacccggtg ccgttcatgg actcgcccgt ggacatcgcc ctgtgcaacc gtgaggaggt
    22021 ctccgacgcg atggacgcca tcgtctccat cgacaccacc aagggcaatc ggctcctcaa
    22081 ccaccggggc atcgccctct cgcccaccat ccggcagggc tgggtgctgc gggtcagcga
    22141 agacctgctg tccgttctgg agaccgtgac cggcgagccc gctcgcgtca tccccgtcac
    22201 cacacaggac atcagcccct acggcaacga cgtccaccac atcaactcgc tgctccaacc
    22261 gtccgtcgcc accgacgccc cggtggtcgg actcgccatc accgcgggca ccgccgtggc
    22321 gggctgcgcc accggcgcca gccacgaacc ggacatcgcc gccgccgccc ggttcgccgt
    22381 ggagaccgcc aaggacttcg gacgcggcgc cgcccacttc tacgaccggg cggaggccga
    22441 ccgcctgatc gagctgtacg gccggatgac gcgtctccag ggccgctccg ccgcccgccg
    22501 acggcccgcc ccaccgcccc gctctctcct ctctcccgcc gagtccccaa gaacacgtcc
    22561 ctggagtccc cgtgccccgt acgtcctccc ctcccgccgg tacgccggac gacgcccccg
    22621 gcacgtccac ggtggagtgc cacccccgc
//
