LOCUS       NZ_CP064271            20714 bp    DNA     circular CON 17-APR-2024
DEFINITION  Priestia megaterium strain N447-3 plasmid pN447-3.1, complete
            sequence.
ACCESSION   NZ_CP064271
VERSION     NZ_CP064271.1
KEYWORDS    RefSeq.
SOURCE      Priestia megaterium (Bacillus megaterium)
  ORGANISM  Priestia megaterium
            Bacteria; Bacillota; Bacilli; Bacillales; Bacillaceae; Priestia.
REFERENCE   1  (bases 1 to 167463)
  AUTHORS   Wang,C., Jia,Z., Zhao,J., Wang,X., Liu,Z. and Ji,F.
  TITLE     Comparative Genome Analysis of key enzyme genes in ammonia nitrogen
            Metabolism Pathway of bacteria from different sources
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 167463)
  AUTHORS   Wang,C., Jia,Z., Zhao,J., Wang,X., Liu,Z. and Ji,F.
  TITLE     Direct Submission
  JOURNAL   Submitted (29-OCT-2020) Guangdong Key Laboratory of Animal
            Conservation and Resource Utilization, Guangdong Public Laboratory
            of Wild Animal Conservation and Utilization, Institute of Zoology,
            Guangdong Academy of Science, Microbial Pathogenic Ecology Group,
            105 Xingang West Road, Guangzhou 510260, China
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: Canu v. V1.5
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 331.67x
            Sequencing Technology             :: Oxford Nanopore
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_022811865.1-RS_2024_04_17
            Annotation Date                   :: 04/17/2024 10:21:34
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 5,644
            CDSs (total)                      :: 5,465
            Genes (coding)                    :: 5,410
            CDSs (with protein)               :: 5,410
            Genes (RNA)                       :: 179
            rRNAs                             :: 14, 14, 14 (5S, 16S, 23S)
            complete rRNAs                    :: 14, 14, 14 (5S, 16S, 23S)
            tRNAs                             :: 131
            ncRNAs                            :: 6
            Pseudo Genes (total)              :: 55
            CDSs (without protein)            :: 55
            Pseudo Genes (ambiguous residues) :: 0 of 55
            Pseudo Genes (frameshifted)       :: 17 of 55
            Pseudo Genes (incomplete)         :: 32 of 55
            Pseudo Genes (internal stop)      :: 11 of 55
            Pseudo Genes (multiple problems)  :: 5 of 55
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 08:04:25
            NOTE :: This is a single region extracted from a cross-origin
            section of a larger, circular record.
            Orig. start                       :: 158220
            Orig. end                         :: 11471
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP064271.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     gene            67..489
                     /gene="arsC"
                     /locus_tag="IQ863_RS27160"
     CDS             67..489
                     /EC_number="1.20.4.4"
                     /GO_function="GO:0030612 - arsenate reductase (thioredoxin)
                     activity [Evidence IEA]"
                     /GO_process="GO:0046685 - response to arsenic-containing
                     substance [Evidence IEA]"
                     /codon_start=1
                     /gene="arsC"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014112792.1"
                     /locus_tag="IQ863_RS27160"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="arsenate reductase (thioredoxin)"
                     /protein_id="WP_047751970.1"
                     /transl_table=11
                     /translation="MSKKTLYFLCTGNSCRSQMAEGWAKKHLNNEEWDVRSAGLEAHGL
                     NPNAVKAMKEAGIDISNQTSDVIDPEILNNADLVVTLCGHAADHCPVTPPHVKREHWGF
                     DDPAKAEGTDEEKWAFFQRVRDEIGERIHRFAETGK"
     gene            607..975
                     /gene="arsD"
                     /locus_tag="IQ863_RS27165"
     CDS             607..975
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0046685 - response to arsenic-containing
                     substance [Evidence IEA]"
                     /codon_start=1
                     /gene="arsD"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010194563.1"
                     /locus_tag="IQ863_RS27165"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="arsenite efflux transporter metallochaperone
                     ArsD"
                     /protein_id="WP_047751969.1"
                     /transl_table=11
                     /translation="MKKVEIFDPAMCCSTGVCGPSVDPELTRVASAVFALEKKGFDITR
                     YNLTSEPNKFVDQVAVNKILMSKGPDALPVVLVDGEVEKTGSYPTNEEFAEWFGVKTEE
                     LKSEKPRMSIKLNINNPK"
     gene            989..2761
                     /gene="arsA"
                     /locus_tag="IQ863_RS27170"
     CDS             989..2761
                     /EC_number="7.3.2.7"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0015446 - ATPase-coupled arsenite
                     transmembrane transporter activity [Evidence IEA]"
                     /GO_function="GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /GO_process="GO:0071722 - detoxification of
                     arsenic-containing substance [Evidence IEA]"
                     /codon_start=1
                     /gene="arsA"
                     /gene_functions="other (smcogs) SMCOG1157: hypothetical
                     protein"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010652166.1"
                     /locus_tag="IQ863_RS27170"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="arsenical pump-driving ATPase"
                     /protein_id="WP_243557734.1"
                     /transl_table=11
                     /translation="MFKSFQPEKMVQTPFLFFTGKGGVGKTSIACAVAVSLADNGHKVL
                     IVSTDPASNLQDVFEIDLRNEPIEIPMVKNLYACNLDPEEAAKTYREKVVGPYRGKLPD
                     AVVSTMEEQLSGACTVEIAAFDEFTNLLANEEMVNQFDYILFDTAPTGHTLRLLQLPSA
                     WTGFLDESTHGASCLGPLSGLDEKRGLYAKTVEALSNPDQTTLMLVARPDVSSLEEANR
                     ASKELKDIGILNQNLIVNGLMSQYVQGDEISTAFYTRQQESLKKMPEELQQMVMYSVPY
                     VSYPLTGINHLRRLFKSETLPETEIKNVELSPEKLTEFKDVVEDFSKNGTKVIFTMGKG
                     GVGKTTVASAIAVGLVEKGHRVHLTTTDPAAHLDFIFSNSEAKELLSISRIDPKAEVDA
                     YKKEVLTKASEELDEDGIAYIQEDLNSPCTEEIAVFRAFADVVAKSNDEIVVIDTAPTG
                     HTLLLLDASESYHKELEKATGEVPESVKTLLPRLRNPKETSVVIVTLAEATPVLEANRL
                     QEDLKRAEITPKWWVINQSLYATDTKDAILKGRSQAEKAWIKKIKNELTSNCAIIPWQP
                     EEKIGYEKVKEYIQ"
     gene            2826..3254
                     /locus_tag="IQ863_RS27175"
     CDS             2826..3254
                     /GO_function="GO:0008138 - protein
                     tyrosine/serine/threonine phosphatase activity [Evidence
                     IEA]"
                     /GO_process="GO:0016311 - dephosphorylation [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006835150.1"
                     /locus_tag="IQ863_RS27175"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="dual specificity protein phosphatase family
                     protein"
                     /protein_id="WP_047751967.1"
                     /transl_table=11
                     /translation="MNNKNYQSLIDNRIFIGGAADVKEIMKNDKVDVIYDLRAESLEHD
                     APEVRVHTPIVDDAENQDESIENAINEVIKSYKEGKKIYFHCAGGSNRTGTIAIGTLLA
                     LGEADSIAEAEEKAKAARAKINVKPEMKASLQRLFPEA"
     gene            3289..3573
                     /locus_tag="IQ863_RS27180"
     CDS             3289..3573
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_332925371.1"
                     /locus_tag="IQ863_RS27180"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="adhesin"
                     /protein_id="WP_047751966.1"
                     /transl_table=11
                     /translation="MNITDGAKKMLEDVFAEQGAKGIRFYSEGAGCCGPQVGLSLDEPT
                     EDDTVQEINGIQVAIENTVLSTTQGLTLDVQEGPQGAGFVLVGMDNSCC"
     gene            complement(4094..4264)
                     /locus_tag="IQ863_RS27185"
     CDS             complement(4094..4264)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016765999.1"
                     /locus_tag="IQ863_RS27185"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="hypothetical protein"
                     /protein_id="WP_168761490.1"
                     /transl_table=11
                     /translation="MERKKFIEHINKLIEQSDAWRKDAEKREDWNSACFYQGEVKAYER
                     VKRLVNQQLHA"
     gene            complement(4582..4770)
                     /locus_tag="IQ863_RS27190"
     CDS             complement(4582..4770)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013083578.1"
                     /locus_tag="IQ863_RS27190"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="IDEAL domain-containing protein"
                     /protein_id="WP_209369536.1"
                     /transl_table=11
                     /translation="MENNVLKNIDPSLRDEMLAELFLDQTMNDFKRSKILKEIDHSLKN
                     KDKQAFLRLTEQLKSVS"
     misc_feature    complement(5210..5228)
                     /note="TFBS match to FuR_variant_2, Ferric Uptake
                     Regulator, confidence: weak, score: 23.46"
                     /tool="antismash"
     gene            complement(5402..7327)
                     /gene="thrS"
                     /locus_tag="IQ863_RS27195"
     CDS             complement(5402..7327)
                     /EC_number="6.1.1.3"
                     /GO_component="GO:0005737 - cytoplasm [Evidence IEA]"
                     /GO_function="GO:0004829 - threonine-tRNA ligase activity
                     [Evidence IEA]"
                     /GO_process="GO:0006435 - threonyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="thrS"
                     /gene_functions="other (smcogs) SMCOG1162: threonyl-tRNA
                     synthetase"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014460609.1"
                     /locus_tag="IQ863_RS27195"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="threonine--tRNA ligase"
                     /protein_id="WP_243557736.1"
                     /transl_table=11
                     /translation="MSKDLIQIRFLDGNEKEFSKGITLHAIAESISSSLKKKAIAGKVN
                     GELYDLHRAINQDAEIEILTVDSDEGLEIMRHTTAHILAQAVKRVHKNVKLGVGPVIED
                     GFYYDMDLSTTIASNELLQLEHEMKKIINENHPIERTEVTRSEAEKIFSEINDELKLEL
                     LRDIPMNETVTIYKQGEFFDLCRGPHLPSTGMVKAFKLTKVSGAYWRGNSDNQMLQRVY
                     GVAFRSQKQLNEYVLFLEEAAKRDHRKLGNELELFMFSDEAPGMPFYLAKGQMVKNQLE
                     QFLRSVQEKHNYEEVRTPFMMNQQLWEKSGHWDHYKDNMYFSEVDNAKFALKPMNCPGH
                     MLIFKNKLHSYRDLPIRMGEFGQVHRHEFSGALNGLLRVRTFCQDDAHIFVTPEQIESE
                     IKSVIELVDYIYKTFGFEYDIELSTRPEDSMGEDSLWELAESSLENVLKKLNFDYKLNE
                     GDGAFYGPKIDFHIKDALKRSHQCATIQLDFQLPEKFDLNYINEKNEKQRPVVIHRAIF
                     GSLDRFFGILIEHFGGVFPTWLAPVQVKVIPVSLKAHQQYAQQIKETLGQKGIRVELDN
                     REQKLGYKIREAQVAKVPYILVLGDKEMESNSVNVRKHGEEKSETFNLDNFIEKLQDEI
                     VEKKLR"
     misc_binding    complement(7378..7604)
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
     misc_feature    complement(7703..7717)
                     /note="TFBS match to SypG, Regulator of biofilm formation
                     and host colonization, confidence: medium, score: 22.73"
                     /tool="antismash"
     gene            complement(7961..9175)
                     /locus_tag="IQ863_RS27200"
     CDS             complement(7961..9175)
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1184: major
                     facilitator transporter"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001082482.1"
                     /locus_tag="IQ863_RS27200"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="MFS transporter"
                     /protein_id="WP_243557738.1"
                     /transl_table=11
                     /translation="MGHTNTKPIFILYVVCISAFFASLNQNIYSPIIPLIKDSFDVSTT
                     LVNLTVSLFIFITAIMQIVYGTILDFKGSRLILLPSLILTVLASIGCAVTSNFTLFLVF
                     RSLQALGTAAIPLIAAATITDLFDGEERGSAMGTYQTLLSIAPAVAPILGGFIGDRYNY
                     DGVFWSLVGISILLLIINMLFFPKDQKKHKTSKRNGLHFYLVMAKDKMGSVLLSLSFLN
                     FLIYFSILVYLPVLLTDHYHLNLKLVGLLYLPMTLSLIAGSLLFKYIQKKISLINIFTF
                     TNFSIAFSVIGFGLTHTVSLLLMSLSLFIYGVGIGILTPSYATILTHQFEQNRASAMGV
                     FNFVRYTGMSIGPILSGTLLEFLRSETMFIMFGVMFGIISIFGYLLVDNPKNTGKNRTT
                     NKPSF"
     region          1..20714
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="CDPS"
                     /region_number="1"
                     /rules="CDPS"
                     /tool="antismash"
     cand_cluster    1..20714
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="CDPS"
                     /kind="single"
                     /product="CDPS"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..20714
                     /aStool="rule-based-clusters"
                     /category="NRPS"
                     /contig_edge="True"
                     /core_location="[10000:10714](+)"
                     /cutoff="5000"
                     /detection_rule="CDPS"
                     /neighbourhood="10000"
                     /product="CDPS"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..10714
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="5000"
                     /detection_rule="CDPS"
                     /neighbourhood="10000"
                     /product="CDPS"
                     /protocluster_number="1"
     gene            complement(9249..9734)
                     /locus_tag="IQ863_RS26345"
     CDS             complement(9249..9734)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001032352.1"
                     /locus_tag="IQ863_RS26345"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="MarR family transcriptional regulator"
                     /protein_id="WP_098113967.1"
                     /transl_table=11
                     /translation="MSLLSKQLIYENYLQLLHLNEQKADSVSQTFFDYLDEKELNEIGT
                     LPSNMSSIHVIECIGNNGPINNIGIATRMNLSKANITKITRTLTKDELIKRFQLADNKK
                     EVYFKLTAKGKQVFELHEKLHSRRKRQFYDLIDDFSDDKQKIILEFLETMINKLRQE"
     gene            10001..10714
                     /locus_tag="IQ863_RS26350"
     CDS             10001..10714
                     /GO_function="GO:0016755 - aminoacyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters) CDPS:
                     CDPS"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010328738.1"
                     /locus_tag="IQ863_RS26350"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="tRNA-dependent cyclodipeptide synthase"
                     /protein_id="WP_243557740.1"
                     /sec_met_domain="CDPS (E-value: 2e-72, bitscore: 236.8,
                     seeds: 17, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSQILLEKIAKPLFAIEPLSQNCQSIFDRRNHILIGISPFNSRFS
                     EEYIYRLIEWSIKEFKGVSVLLAGNEAANLLEALGTSRVKAERKVRKEVNRNRRFAERA
                     LKAHGGNPEAIYTFSDFITQPVYCDMRTKIEESFLHQPNFQNACLEMSHAAIVGRASGT
                     NMDISVITSEMLHNAVQYVLAELPFFIGAPNILGIQETVLAYHKPWRLGEQIKDEQFSI
                     RMQQNQGYITVDEIH"
     gene            10747..11970
                     /locus_tag="IQ863_RS26355"
     CDS             10747..11970
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) p450"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1007: cytochrome P450"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010332029.1"
                     /locus_tag="IQ863_RS26355"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="cytochrome P450, cyclodipeptide
                     synthase-associated"
                     /protein_id="WP_243557742.1"
                     /sec_met_domain="p450 (E-value: 1.5e-40, bitscore: 132.6,
                     seeds: 50, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNTSFKTFSILSEQFHEDPYQYFSELRDFDPIHYEQDIDSYFISR
                     YKDVRYVLQNTEIFTTKSLAKRAEPVMRGPVLAQMKGKEHTAKRKIVVKSFIGDSLKRL
                     IPLIKENAEVLLSPHLSKGRIDLVNDFGKTFAVYVTMDMLGLNKKDHQLIADWHSGVAN
                     FITTIQLSSEERDHSLWCSEQLANYLLPIIEERRQNPKSDLISILCQSEYEGVEMSDTN
                     ILALILNILLAATEPADKTLALLMYYLLNNPLQMQDVMEDRSLLSRAIAETLRFKPPVQ
                     LIPRQLSQDAKIADRLLPKGSTVFCMIGAANRDPEAFDNPDTFNIHRPDLDVKTAFTGI
                     ARHVAFGSGIHNCVGAAFAGTEIEVVANIVLDQLQNMKLEEGFHYTESGLYTRGPVSLP
                     LTFNPIKG"
     gene            complement(12041..12505)
                     /locus_tag="IQ863_RS26360"
     CDS             complement(12041..12505)
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003185275.1"
                     /locus_tag="IQ863_RS26360"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="MarR family transcriptional regulator"
                     /protein_id="WP_243557744.1"
                     /transl_table=11
                     /translation="MEALHKQAFQAIESLIMTREKKVQSRKMLANKLTQSVNSTNKKWT
                     ITQLHIVSLINKDQYVNNALLSKELNISKPAVSKAINTLVGHGIVLANKNIHNNRETFY
                     SLTKEGEELAEVHDKMHEIAEKRYVELLNKFSEVELKIIIKFLNEWTKQI"
     gene            complement(13207..13800)
                     /locus_tag="IQ863_RS26365"
     CDS             complement(13207..13800)
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1239: TetR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009710979.1"
                     /locus_tag="IQ863_RS26365"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="WP_243557746.1"
                     /transl_table=11
                     /translation="MGTRPGLDLDTILKATTEMANTQGLDEVTLASLAKKLNIRPPSLY
                     NHINGLPALRKKLAVYGYEQLYKVLIHATVGRAKDNAVRALGEAYIVFVRNHPGLYEAM
                     LRSPNSDDLELKHIQNETINIVIQVLNEYGLGEEQTLHATRGLRSILHGFASLEQKKGF
                     GLPHDLDVSLLMLIDIFLRGINAMKQESKNNEDD"
     gene            complement(13826..14539)
                     /locus_tag="IQ863_RS26370"
     CDS             complement(13826..14539)
                     /GO_function="GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1170: metallo-beta-lactamase family protein"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002124207.1"
                     /locus_tag="IQ863_RS26370"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="WP_243557748.1"
                     /transl_table=11
                     /translation="MRISHEAYLHQLTFLPGFFPVNCYLVEESDSLTLVDAALPYSAKK
                     ILKAAKKINKPITRILLTHAHDDHVGALDKIKQLLPNVPVHISSRDARLMGGDITLDPN
                     EPNTPIRGGVPKNLKTRADILLQDGDQIGSLIAIAAPGHTPGSMAFFDTRTNTLIAGDA
                     FQTRGGMAVTGQLQPLFPFPAMATWNKEVALQSAHKLLNYNPSLLAVGHGKMIKRPEKA
                     INNAITKARLNLEQI"
     gene            complement(15021..16733)
                     /locus_tag="IQ863_RS26375"
     CDS             complement(15021..16733)
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1005: Drug
                     resistance transporter, EmrB/QacA"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019392349.1"
                     /locus_tag="IQ863_RS26375"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="MFS transporter"
                     /protein_id="WP_341722282.1"
                     /transl_table=11
                     /translation="MMRKKSHTKILLLMCLGIFICMIDSTIMNITLPAIQEDLHTTLET
                     SSWMLNVYTMTIAVLAIPMARFADMFGRNKFYLLGLIVFGLGSLLCGLSMSANFLLIAR
                     FTQSLGAAILIPLSMVIGVGIMPTEKRMISLTLLGATQGLSTALGPTIGGIITEKLDWH
                     WVFYVNIPICMIGVIACVFLLPLKQEKTVKAKIDWGGLIFSTIALFTATLVLIKGNSWG
                     WTSQEALICYLTSMISLVLFIVIEKRVQDPMIKLSLFQDRQFLGSVLTVSAGYVFLIGV
                     MVLLPQFLTRFQGKTELEAALLVTPVSAAIFFFSQLAGLLVKKVGFIVPVILGFLIMGS
                     AYYLLENLSINSTTTEIITLCTLLGVGFSFIIATATIASTSSFEGELLTASQGVFSMLR
                     QVGVVLAVAIFVGGLTNKIYQNQDKVMRYAQTQLNQLNIEKAEQTRVLRHTKNALYSDK
                     EHVEVDSQLSKKQIDRMINQNAEDILKDMPLNKRKVAKPLIYKQVSEKIEKKQTEIDKY
                     SKKVNEYGTDKIASSFSNLYKSTVPFVFVCAFLGFTFRKKNQKKIVTEQLKIN"
     gene            complement(16734..17255)
                     /locus_tag="IQ863_RS26380"
     CDS             complement(16734..17255)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1278: PadR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007086382.1"
                     /locus_tag="IQ863_RS26380"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="PadR family transcriptional regulator"
                     /protein_id="WP_243557752.1"
                     /transl_table=11
                     /translation="MNIQNVILGFLAEKPMSGYDIKQMMENSVSYFFEASYGAIYPALR
                     RMEKDELIEKEVIQQEGKPNKNLYVITSKGEKEFQEYMNSPLNPTLIRSDLLIRIFFGQ
                     YTSFDKIKEWLNTEKQKAQAQLDNLTSLNEKYPNMERHKKITLLYGIDEAKFTLVWIER
                     ELQQLMSKGN"
     gene            complement(17572..18252)
                     /locus_tag="IQ863_RS26385"
     CDS             complement(17572..18252)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016124259.1"
                     /locus_tag="IQ863_RS26385"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="hypothetical protein"
                     /protein_id="WP_243557754.1"
                     /transl_table=11
                     /translation="MFDIHIMDWAKKRPKKHHNNIHGLRVFELIFCRKLKDLGFELDEL
                     NSIAVYCLANPNKDVSYSEEKAIHEVEILLPDDYMLFIELESVEEKYQAFCNIVRKYIV
                     PTLEKYSSFSLVTIQKYVEEALEEIVRQDYEAIFIAAKTPKKSPNRKLLAMLKGVHRYS
                     GFQLWCEVYNERGLRIINELLVEEVGNEAVYSRFLGELKWKSNQLITVKSKTSSWMREV
                     HIPL"
     gene            18474..18824
                     /locus_tag="IQ863_RS26390"
     CDS             18474..18824
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000232878.1"
                     /locus_tag="IQ863_RS26390"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="YxiJ-like family protein"
                     /protein_id="WP_226556667.1"
                     /transl_table=11
                     /translation="MLDELKKLNDDLYHPFPHEDICKIQDKFSVKLHEDDLLTADFNSY
                     WMNIAGSLSYMLKGKTKKIPRNQIDELKLTFFEAFPQYSFLEEEISTYPNLYEEYKVYE
                     KARELMLSYLFN"
ORIGIN
        1 tacacttgtt ggtttatata tttggttact tattatttca taacatttct aaaggagatt
       61 tgacacatgt ctaaaaaaac actttatttc ttatgtacag gtaactcttg ccgtagccaa
      121 atggcagaag gttgggcaaa aaaacatcta aataatgaag aatgggatgt acgcagtgca
      181 ggtctggaag cacatgggct aaaccccaat gctgtcaaag cgatgaaaga agcaggcatt
      241 gatatttcga atcaaacatc tgatgttatt gatcctgaaa ttttaaataa tgcggattta
      301 gtggttacat tatgtggcca tgcagctgat cattgccccg taacgcctcc tcatgtaaaa
      361 cgtgaacact ggggatttga tgatccagca aaagcagaag gaacagatga agagaaatgg
      421 gcattcttcc aacgtgtacg tgatgaaatc ggagagcgta ttcaccgttt tgctgaaaca
      481 ggtaaataat cattaaaatt aaatagccgg gagagtttct ctcggcatat cctttatctt
      541 ttatataagt atattattat aaactacttt taaaaaggta tagtctacat aaagggagat
      601 gaaattatga agaaagtaga gatttttgat ccagctatgt gttgttcaac aggtgtttgt
      661 ggtcctagtg ttgatcctga attaacaagg gtggcttcag ctgtattcgc cttggagaaa
      721 aaagggttcg atattacacg ttataactta acaagcgaac caaataagtt cgttgatcaa
      781 gtagcagtta ataagattct tatgagtaaa ggtccagatg ctttaccagt ggtattagtg
      841 gatggtgaag tagagaaaac tggaagctac ccaaccaatg aagaatttgc tgaatggttt
      901 ggtgttaaaa ctgaagaatt aaagagcgaa aaaccacgca tgtcgatcaa attaaatatt
      961 aataatccaa aatagggagg taaaagaaat gttcaaatct tttcaacccg aaaaaatggt
     1021 tcaaacaccc tttttatttt ttacaggtaa aggcggtgtt ggcaaaacat ccatagcatg
     1081 tgctgtagct gtttcgttag cagataacgg tcataaagta ctgattgtta gtacagatcc
     1141 tgcttcaaat ttacaagatg tatttgaaat tgacttgaga aacgagccaa ttgagatacc
     1201 gatggttaaa aatttatatg cttgtaacct ggaccctgaa gaagcagcaa aaacataccg
     1261 tgagaaagtc gtaggacctt atcgtggaaa actccctgat gctgttgttt ctactatgga
     1321 agaacaatta tctggagctt gtacggtaga gattgctgca tttgatgagt ttacaaattt
     1381 acttgctaat gaagaaatgg tcaaccagtt tgattatatt ctttttgata cagcgccaac
     1441 agggcataca cttcgcttgt tacaattgcc aagtgcatgg actggtttct tagatgaaag
     1501 tacacatgga gcttcttgtt tagggccttt atcaggtcta gatgaaaaga gaggtttata
     1561 cgcaaaaacg gtagaagctt tatcaaatcc ggatcagacg actttaatgt tagtggctcg
     1621 gcccgatgtt tcttctctag aagaggcaaa tagagcttca aaagaattaa aagatattgg
     1681 cattttaaat caaaacttaa ttgtgaatgg gttaatgagt caatatgtac aaggcgatga
     1741 aatatctact gctttttata ctcgacaaca agaatcatta aagaaaatgc cagaagaact
     1801 tcaacaaatg gttatgtatt cagtgcctta cgtatcttac cctttaacgg gtattaatca
     1861 tttacgtcgt ttgtttaaat cagagacatt accagaaacc gaaattaaaa atgtagagct
     1921 ttctccagaa aagttaaccg agtttaaaga tgttgtagaa gacttctcta aaaatggaac
     1981 aaaagttatt ttcacaatgg gtaaaggcgg tgttggtaaa acaacagtag catctgcgat
     2041 tgcagtagga ctagttgaaa aaggccatcg tgttcattta actaccacag atcctgcagc
     2101 ccatttagat tttattttta gtaatagtga agcaaaggaa ttactaagca tcagtcgaat
     2161 tgaccctaaa gctgaagtag atgcttataa aaaagaagta cttacaaaag ctagtgagga
     2221 acttgatgaa gatggcattg cttatattca agaagactta aattcaccat gtacagaaga
     2281 aattgctgtg tttcgagctt ttgcggatgt ggtagctaag tcaaatgatg aaattgtagt
     2341 cattgataca gcaccaactg gtcatacgtt gcttttactt gatgctagcg agtcttatca
     2401 taaagaattg gaaaaagcta caggagaggt tccagaaagc gttaaaacgt tactgccacg
     2461 tttacgtaat ccaaaagaaa cgagtgtagt tattgtaact cttgcagaag caacgccagt
     2521 attagaagcg aatcgtcttc aggaagactt gaaacgtgct gaaattacgc caaaatggtg
     2581 ggttatcaac caaagtctgt acgcaacaga tacaaaggat gctattttaa agggaagatc
     2641 acaagctgaa aaagcatgga ttaagaaaat aaagaatgaa ttaacatcta attgtgctat
     2701 tattccctgg caaccagaag agaaaatcgg ttacgaaaaa gtcaaagagt atattcaata
     2761 attcaaagtg ggaagtaacc tgtttttata atgattcaga cattaaaatt atagaggtgg
     2821 acaacatgaa taacaaaaat tatcaatcat taattgacaa tcgtattttt attggtggtg
     2881 cagctgatgt aaaagaaata atgaaaaatg ataaagtaga tgtgatttat gacttacgtg
     2941 cagaatcatt agaacatgat gctccagaag tacgtgttca tacgccaatt gtagatgatg
     3001 cagaaaacca agatgaatct attgaaaatg caattaatga agtaataaaa tcgtacaagg
     3061 aagggaagaa gatttacttc cattgtgcag gaggaagtaa tcgtactggt acgattgcaa
     3121 ttggaactct gttagcactt ggagaagctg attccattgc agaagccgaa gaaaaagcaa
     3181 aagcagctcg tgctaaaatt aatgtaaaac ctgaaatgaa agcttcactt caacgtttat
     3241 ttccagaagc ttaaccaata aatataattg aagataggga gagattagat gaatatcaca
     3301 gatggagcta aaaagatgtt agaagatgta ttcgctgaac aaggagctaa aggcattcgt
     3361 ttttactctg aaggtgctgg atgctgtgga cctcaagtcg gtttatcatt agacgaacct
     3421 actgaggatg atacagtcca agaaattaac ggtattcaag tagctattga aaatacagta
     3481 ctatctacaa ctcaagggct tacacttgat gttcaagaag gtcctcaagg tgcaggattt
     3541 gttttggtag gaatggataa cagctgttgt taattaaata attaacttta aaactgtaga
     3601 atatatgtgg taaaaagaga aggttaaaat cttctctttt ttatttacct ttgtttactt
     3661 ctttttagga cctagaagat acaattcgtt atgctgccag tgattctcat tacgttctac
     3721 ttcaattttt gatacaactt tagatttccc attcagttga tgaaaaatat acgcgactaa
     3781 gccacgttcc aacatataaa gaagagcata tattttataa acatctaatg atcacctgct
     3841 gctgtatagt ttctttttat ttctatgagt agacaggcaa aattgtgggt tttaatataa
     3901 aaaagcgcag tctaagacac tcaaacgatt ttactctatc tataaactaa ctctatgcac
     3961 ttactattat attggaccat aaaatgcccc ctttctcctg aaataaattg gttcctagaa
     4021 tgtatcttat gtaaactaga aaaagaaata aggcaaaccc tcctcatttc tgagttaggg
     4081 ttgtaatttt tatttatgca tgtaactgct gattaaccaa tctttttact ctctcataag
     4141 ctttgacctc tccttggtaa aaacatgcac tgttccagtc ttcccttttc tctgcatcct
     4201 ttctccacgc atcagattgt tctattaact tattaatgtg ttcaataaac ttctttcgtt
     4261 ccatttaatc acctgctttt attataattg gaaatattta tacggaattt tgataattaa
     4321 tatttctaga atttagtgag aatacctgtt ggaatttaat ataacctcca ggacttttag
     4381 gaataaaaga aatgaccctt agtaatgaaa gtaatttctt ttattttatt gcctgtttat
     4441 gctcatttta atgagtcatt ttggttcttt ttgattttag aaatattact tatgttaatt
     4501 taaaagaaat aaaaagaagc ctcagtcttt aaaaaggaag gcttcttttt aatgaatttc
     4561 ttctatatta catcgttttt attaagatac agatttaagt tgctctgtca aacgtaaaaa
     4621 agcttgttta tccttattct ttaaagaatg gtctatttcc ttaaggatct tacttctttt
     4681 gaagtcgttc atcgtttgat ccaaaaacaa ttcagccagc atttcatcac gtaaacttgg
     4741 atcaatgttt ttaagcacat tattttccat taaaaatcaa cccctttatc ttttctcctc
     4801 tttaaacatt attaaccttt ttgacgtcgt ttatgcgaga ttgatagata aagtgaaata
     4861 atgaatatat ttaccccgtg tattgataat cctcttgtta ttctgattat tatttcatac
     4921 ttataaaccc caaagcgagc acaaaaactg tgttatttat ttgttgaagg agatttataa
     4981 actaactttt aagaatatag gttctgccaa tcatgtttaa caacggcaaa ccactagctt
     5041 aatctatttt cttatcagaa acgttcgtaa aagtgtatag ttttagaaga cgttcgtcat
     5101 ttattttcaa acttaatcga acgatgaaaa tgacaggttt tctatataag agaaaagttc
     5161 gtaaacatat acttttacgg actttaaaat ttcttattct atttaataag tggagaaacg
     5221 ttctcaaagg agattaactt taattttaca tagaacaaga acaattaatg cgaatctcag
     5281 cgctttaaat ttttttgatt tttactatca tcaatccttc aagatcctgt taccataaac
     5341 attattatta gaacaaaaag aaggttccgt gtcgaatgtt aaggaacctt ctttttgttc
     5401 attatctcag tttcttttca acaatttcat cctgaagttt ttcaataaag ttatctaaat
     5461 tgaacgtttc agacttttcc tctccgtgtt ttcgtacatt tacggagtta ctttccattt
     5521 ccttatctcc taataccaaa atataaggaa ccttagccac ttgagcttct cgaatcttat
     5581 atccgagctt ttgttctcga ttatctaatt ctactcgaat tcccttctgt cctaacgttt
     5641 ctttaatttg ttgtgcatat tgctggtggg ctttcagcga tacgggaata acctttacct
     5701 gtacaggtgc caaccatgtt gggaagaccc ctccaaagtg ttcaattaaa atcccaaaga
     5761 aacggtcaag agatccaaaa atagcacggt gaatgacaac tggacgctgt ttttcgttct
     5821 tttcgttaat ataatttaaa tcaaattttt ctggaagctg gaagtctaat tgaattgttg
     5881 cacattgatg acttcttttt aaggcatctt taatatgaaa atcgatttta ggaccataaa
     5941 atgctccgtc gccttcattc agtttataat caaagttcaa tttttttaat acgttttcta
     6001 aagagctttc agcaagttcc cataagctat cttctcccat agagtcttct ggtcgagttg
     6061 aaagttcaat atcatattca aaaccaaatg ttttgtagat ataatcgact aattcaatga
     6121 ccgatttaat ttcactctca atttgttcag gagtaacaaa gatatgagca tcgtcctgac
     6181 aaaacgtacg aactcttaat aatccattga gagctccact aaattcatga cgatgaactt
     6241 gaccgaattc tcccatgcga attggtaaat ctctatagga atggagctta tttttaaaga
     6301 taagcatatg gccaggacag ttcataggct ttaatgcaaa tttagcgtta tcaacttctg
     6361 aaaaatacat attatccttg taatgatccc aatgaccaga cttttcccat aattgttgat
     6421 tcatcataaa aggagtacgt acttcttcgt aattatgctt ttcttgaacg gatcgtagga
     6481 attgctccag ctgattttta accatttgtc ctttagctag ataaaaaggc attccaggtg
     6541 cttcatcaga aaacataaat aattctagtt catttcctaa ctttcgatga tctcttttag
     6601 ctgcctcttc taaaaatagt acatactcat ttaactgttt ttgagaacgg aaagctacgc
     6661 catatacacg ttgtaacatt tggttatcgc tgttacctct ccagtatgct cctgatactt
     6721 ttgttaattt aaacgcctta accattccag tagaaggtag gtgagggcca cgacataaat
     6781 cgaaaaattc cccttgttta taaattgtaa ctgtttcatt cataggaata tcacgtaata
     6841 actctagttt caactcatcg tttatttcgc taaatatttt ttcagcttca ctgcgtgtca
     6901 cttcagtacg ttcaataggg tgattttcat taataatttt cttcatttca tgttcaagtt
     6961 gtagtaactc attagaagca atcgttgtag aaagatccat atcgtaataa aatccatctt
     7021 caataactgg gcctacacct aacttcacat tcttatgtac tctttttact gcctgagcaa
     7081 gtatgtgagc tgttgtatgc ctcataattt ctagaccttc gtcagaatct actgttaaga
     7141 tttcaatttc tgcatcttga ttaatagctc gatgcaagtc atataattct ccatttactt
     7201 tacccgcaat ggctttcttc tttaggctag aactaatgga ttctgcaata gcatgtaatg
     7261 taataccttt tgaaaattct ttctcatttc catctaaaaa gcgaatttga attaaatctt
     7321 tactcatgat aacctctcct atttaaataa agtcaaaaaa aacatactca tccctaagta
     7381 agggacgagt atgttttcac acgtggtacc acccaaattc ccatcaatag aaatatatcg
     7441 atggctctgg tgctgtaacg tcgcaaacgt tattaattac tactagttca ctaataaagc
     7501 tccaaggtgg taaattattt ctctttctta agggctcaca gccaaagacc ctattctctg
     7561 caaagaagta taaaaataat tcatgtcctt ttcgttgctt atctatttat ttttgaacat
     7621 aaaaaaacgc actcatccct ctaacaggga cgagtgcggt cgtggtacca ccctaatttt
     7681 ataaaacact acaagtgtta tattctcaaa aagataacgg atttcccgat tgaggttact
     7741 ctatctacat atttccccac aatagctcca aggtggtaaa ttatttctct ttcttaaggg
     7801 ctcacagcca aaggccctat tctctgtaaa gaaatataaa aataattcgt gtccttttca
     7861 acgctcaaca tgttcatttc caataaatag aattataatt tatactattt gtaaatgtca
     7921 atacttaatt ctaaatatgt tattaattgt atgtttttgt ttaaaaagat ggtttattgg
     7981 tagttctatt tttacctgtg tttttggggt tgtccactag taaataacca aagatactta
     8041 taatgccaaa catgacaccg aacattatga acatggtttc acttctcaaa aattctagta
     8101 atgtacctga caaaatgggt cctatagaca taccagtata tctaacaaag ttaaatactc
     8161 ccatagcact agctcgattt tgttcaaatt gatgggttaa tatggttgca taggaaggtg
     8221 ttaagattcc aattcccacc ccataaatga ataggcttag cgacataagt agtaaagaaa
     8281 cagtatgtgt gagtccaaat cctataacac taaatgcgat tgaaaaatta gtaaaggtaa
     8341 atatatttat aagagaaatc ttcttctgaa tgtatttgaa taacagactt ccggctataa
     8401 ggcttagcgt cataggaaga taaagcaagc caacaagttt taggtttaga tgatagtggt
     8461 ctgttaataa aacggggaga taaaccagga tagaaaagta aatcaaaaag ttcaagaagc
     8521 ttaatgacaa caatacactt cccatcttat ccttcgccat tacaaggtaa aaatgaagac
     8581 cgttcctctt gcttgtcttg tgctttttct ggtctttagg aaaaaacaac atattgataa
     8641 taagtaaaag aatagatata cccactaatg accagaaaac accatcataa ttgtatcggt
     8701 ctcctataaa tcctcctaaa ataggagcta ctgcaggagc aatagataac aaggtttgat
     8761 aagttcccat agcactacca cgttcttccc catcaaaaag atccgttatt gtagcagctg
     8821 caatcaatgg aatggctgcg gttccgaggg cttgcaaaga tcgaaaaaca agaaacaatg
     8881 taaagttact tgtaacagca cacccaatac tagccaacac tgtaagtata agactaggga
     8941 gaagaataag acgacttcct ttaaagtcaa gaatagtccc gtagactatt tgcataatag
     9001 ctgtaataaa gatgaacaat gaaacagtta aattaactaa tgttgtgctt acatcaaatg
     9061 aatccttaat taacggaata ataggcgaat aaatattttg atttaaagat gcaaaaaatg
     9121 cacttataca aacgacgtat aagataaaaa taggttttgt atttgtatgt cccatataaa
     9181 tctcctacct tgtaaataag tttttccata taaaagtatg tttgacattc taaaagcacc
     9241 taatgtgtct attcttgtct taatttatta atcatcgttt caaggaactc taatataatt
     9301 ttttgtttgt catcagagaa atcatcaatt aaatcataaa attgtcgttt ccttctgcta
     9361 tgtagttttt cgtgaagttc gaaaacttgt tttccttttg ctgttaactt aaagtagacc
     9421 tcttttttat tgtctgccaa ttggaatctt ttaattaact catctttcgt taatgttcgg
     9481 gtaattttcg tgatatttgc tttagataaa ttcatcctag tcgcaatccc tatgttattt
     9541 ataggtccat tatttccaat gcattcaatc acgtggatgc tgctcatgtt actgggtaat
     9601 gttcctattt cgttcagttc tttttcatca agataatcaa aaaaagtttg ggaaactgaa
     9661 tcagcttttt gttcgttcag gtgtaataat tgcaaataat tttcgtatat taactgttta
     9721 gataatagag acatattagt tccttacctt tctaatgtat aaataattaa tgttcaccag
     9781 taaacattat actactaata agctattaaa tgaatgtaaa atctcttttt atacaataaa
     9841 atcagatttc atagtaatta aaacctacta tatttgcaga aaaaacgctt ataaatttac
     9901 aaaataaaga aaaacgttga cttttacaaa tatttggatt taaaatagtt tttgtttact
     9961 agtgaacatt aaccgtttaa tcataggagt tgaaatagct atgtcacaaa ttcttttaga
    10021 aaaaatagct aagcctttat ttgctattga acctttatca caaaattgcc agagcatttt
    10081 tgacagaaga aaccacatat taataggaat tagccccttt aacagtagat tttcagagga
    10141 atatatttat cgactaattg agtggagcat taaagagttt aagggtgttt ctgttctctt
    10201 agctggaaat gaggctgcaa atcttttgga agctttagga acttctaggg tgaaagctga
    10261 gcgtaaagtg agaaaagaag taaacagaaa tcgtcgattt gccgaaagag ctctcaaagc
    10321 tcatggtggt aaccctgaag ctatttatac attttcagac tttattactc aaccggtata
    10381 ttgtgatatg cgcactaaga ttgaagaaag ttttttacat caaccaaact ttcaaaatgc
    10441 ttgtttagaa atgtcacatg cagcaattgt aggaagagca tctgggacaa atatggatat
    10501 ttcagttatt acttcagaaa tgttacataa tgctgtgcaa tatgttttgg ctgaactgcc
    10561 gttctttatt ggagcaccta acatcttggg tattcaagaa actgtacttg cttaccataa
    10621 accttggaga ctaggtgaac aaataaaaga tgagcaattt tcaattagaa tgcaacaaaa
    10681 tcaaggatat ataactgtcg atgaaattca ttaaatttac acctttaaat tttaggagga
    10741 acagtcttga atacatcatt taaaaccttt agtatcttat cagaacagtt tcatgaagat
    10801 ccataccaat atttttcaga acttcgcgat ttcgatccta tccattatga gcaagatatt
    10861 gatagctatt ttattagccg atataaagac gtaaggtatg tattacagaa tacagaaatc
    10921 tttacgacta aatctcttgc taaacgtgct gaacctgtaa tgcgtggacc tgtccttgca
    10981 caaatgaaag gaaaggaaca tacagcaaaa cgtaaaattg tagtaaaaag ctttataggt
    11041 gattcactta agagactcat tcctttaatt aaagaaaacg cagaagtttt attgtcacca
    11101 cacttaagta aagggagaat cgatttagtt aacgattttg gaaaaacttt tgcagtatat
    11161 gtcacgatgg atatgctagg acttaacaaa aaagatcatc aacttatcgc agattggcac
    11221 agtggagttg ctaactttat cactactata cagttgtcat ctgaagaacg tgatcattca
    11281 ttatggtgca gtgaacaact agcaaactac cttttaccca ttatagaaga gcgtcgacaa
    11341 aacccaaaat cagatctcat ttcaatatta tgtcagtctg agtatgaagg agttgagatg
    11401 tccgacacga acattttggc acttatcctt aatatactat tagcagctac cgaacctgca
    11461 gacaagacat tggcattgtt aatgtattat ttattaaata atccgttaca aatgcaagat
    11521 gtgatggaag atcgttcatt attatcaaga gcaattgccg aaactctaag gtttaaacca
    11581 ccagtacaac ttataccaag gcaattatcg caagatgcga aaatagccga tagattacta
    11641 cctaaaggtt caaccgtatt ctgtatgatt ggggctgcca atcgagatcc tgaagcgttt
    11701 gataatcctg atacttttaa cattcatcgt cctgaccttg acgtcaaaac ggctttcaca
    11761 ggtattgctc gacatgtggc tttcggttct ggcatacaca actgtgtagg agctgccttt
    11821 gcaggaacag aaattgaagt agtagctaac attgttttag atcaactaca aaacatgaaa
    11881 ttagaagaag gatttcatta cacggaaagt ggtctttata cacgtggacc cgtttctctt
    11941 ccattaacgt ttaatcctat taaaggctaa gataataaat tgtatacaat taagcaagtg
    12001 gatttacgac atgctcatta ggcatgtcgt aaacctactt ctatatttgt ttggtccact
    12061 catttaaaaa tttaataatt atttttaact ctacttctga aaatttatta agtaattcta
    12121 catatctttt ctctgctatt tcatgcattt tatcatgaac ttcagctaac tcctcccctt
    12181 cctttgtcaa ggaataaaag gtttccctat tattatggat attcttgttt gctagaacaa
    12241 tgccatgtcc cacaagtgta ttaatagcct tagatacagc aggttttgag atattaagtt
    12301 ctttagaaag aagagcattg tttacatatt ggtctttatt tattaatgaa acaatatgta
    12361 attgagtaat tgtccatttt ttattcgtac tatttacact ttgagttagt ttattagcta
    12421 gcattttcct actttgaacc tttttttctc tagtcataat tagagattca atagcttgga
    12481 acgcttgctt atgaagagct tccatcagaa acacaccttc ttcaatataa ttgttaactg
    12541 gttaactata tataatagtt tactggttaa cgtttatatt gtcaagttta tttgatttag
    12601 gctttgcata caatataact gattgatagg atacattagc cttctttgtt tataaaaaat
    12661 taatatatac ggctgccttt ttataatagg ttccggaaac atgtcttatg ttaactatag
    12721 aagtaaacct ttgcgaacta attaaaaaac tattttatgt aacgcatagg gtgtaaaaga
    12781 aacttcccaa aaaacgatta ctctaatctg agtaatcgtt ttttgggttt taaccatcta
    12841 tacgttttag tgtcattgtt gctgccagat atacattaaa atgcggttta ttatagcaat
    12901 tgtaatataa ataagtgcca gagaatgctt accactagtg tatagggcaa cagaaggaag
    12961 cccaaatata agaagttcga gcaaaatatg aataggggta gatagttgaa cgtaagaacg
    13021 aggagaacca aaaatccccc aaactactgc aattattaac ggagcaccta ttgataaaag
    13081 cactctcatt gacccttttc cagtttgaaa tccccagtaa gctagtgagc caagtgcgaa
    13141 caattccaaa gaaaatcgca acatcaaatt taaagttttg atgaaaggaa gaagattcat
    13201 attaaattaa tcgtcttcat tgtttttact ctcttgtttc atcgcattta ttcctcttaa
    13261 aaaaatatct attaacatga gaagacttac atcaagatca tgggggagac caaatccttt
    13321 tttctgctca agtgaagcaa agccatgtaa aatacttcgt agtcctcgtg tggcgtgtaa
    13381 agtttgctct tctcctaagc cgtattcgtt aagtacttga atgacgatat taatggtttc
    13441 gttctgtatg tgcttaagtt ccaggtcatc agaattagga gaacggagca ttgcttcata
    13501 caaccctgga tgattacgaa caaaaactat gtaagcttcg cctaatgcac gaactgcatt
    13561 atcttttgca cgtcctacgg ttgcatgtat taatacttta taaagttgtt cgtaaccata
    13621 aacagctaac tttttccgta atgctggtaa gccatttata tgattatata aagaaggtgg
    13681 acgaatattt aattttttag caagtgaagc taatgttact tcatctaatc cttgcgtatt
    13741 tgccatttct gtagtggcct ttaaaatagt gtctaaatca agtcccggtc ttgtgcccat
    13801 agttaaattc ctttcttact ataggttaaa tttgttccaa atttaaccta gcttttgtaa
    13861 ttgcattgtt tatagctttt tccggtcgtt ttatcatttt tccatgccct acagcaagca
    13921 atgaaggatt gtaattcaat aacttgtgag cactctgaag tgcaacttcc ttattccatg
    13981 tagccattgc tggaaaggga aataaaggtt gaagctggcc agttactgcc ataccacccc
    14041 gtgtttgaaa ggcatcacca gcaattaagg tattagtacg ggtatcaaaa aaagccattg
    14101 aacctggcgt atgtccagga gcagctatcg caattagtga accaatctgg tcaccatctt
    14161 gtaataaaat gtctgctcgg gtttttagat ttttaggtac tccgccacgt ataggagtat
    14221 tcggttcatt aggatccaac gtaatatccc cacccattaa tcgggcatct ctacttgaaa
    14281 tatgtacagg aacattggga agtaattgct ttattttatc aagtgctcct acatgatcgt
    14341 cgtgcgcatg ggttagaaga atacgtgtaa taggtttgtt aatcttttta gcagctttta
    14401 atattttctt agcactgtaa ggaagcgcag catcaactag agttaaacta tcactctctt
    14461 caactaagta acaattaact gggaaaaatc ctggtagaaa agtcaattga tgcaagtatg
    14521 cttcatgact gattctcata ggaatacctc cttctgatat tagctttaaa actatttcca
    14581 tttatatatt aactaatgtc attagttaac gcaagttaat atacatttta tttgttaaaa
    14641 ttaagataaa tgcccaataa ttagatgggt attttatatt ttaaggtgtt aaaacagaag
    14701 aaaaggtcac agacgtatac ttttacgaac actaatcaat ttattaaaag gtatctacat
    14761 aagtggctat atgttcatta aagatattga attaagggag aaaaacccca agtagctgta
    14821 attaatacac agagatataa tctctgagaa aattaacttt tgtttatgta taataaatta
    14881 ttcgatgtaa gcttcaacgt tttaagcatt taattctttt ctatttaaag tagttacact
    14941 accagaaaca tcacaaaaag ccctttattt agggcttttg catataagtt attattagct
    15001 attaatagac aattatcacg ttaatttatt ttcagttgct ctgtaactat ttttttctga
    15061 ttcttctttc tgaacgtaaa tcctaaaaag gcacaaacaa atacaaaggg aacggtagat
    15121 ttataaaggt tactaaagct actcgcaatt ttatctgttc catactcatt gacttttttc
    15181 gaatatttat ctatttctgt ttgttttttt tctatcttct cagatacttg tttatatatt
    15241 aacggcttag ctaccttcct cttgtttaaa ggcatgtcct ttaatatatc ttctgcattc
    15301 tggttaatca ttctatctat ttgcttttta gaaagttgac tatctacttc cacatgttct
    15361 ttatcggaat aaagagcgtt ctttgtatgt cgtaataccc tagtttgttc agctttctct
    15421 atattgagtt gattcaattg tgtttgagca tatctcatta ctttgtcttg attttgatag
    15481 attttattgg ttaatcctcc aacaaaaatg gcgactgcta gaacaacacc aacttgtcga
    15541 agcatggaga ataccccttg tgaagctgtt aataattcac cttcaaatga agaggtgctt
    15601 gctattgtag cagtagcaat tataaagcta aatccaaccc ctaataatgt acataatgta
    15661 atgatttccg ttgttgtact attaatactt aaattttcta gaaggtagta agcactcccc
    15721 ataataagaa atcctagaat aacaggaaca ataaagccaa cttttttaac caataaccct
    15781 gctaactgtg aaaaaaagaa gattgctgct gatacaggtg taacaagaag agctgcctct
    15841 aattccgttt ttccttgaaa ccttgtcaaa aattgtggta gtaacaccat cactccaatt
    15901 aaaaagacat atcctgccga tacagttaat acggatccta gaaactggcg gtcttggaag
    15961 agggacaatt taatcatagg atcttgtact cttttttcta ttacaataaa taaaacgagc
    16021 gagatcatac tagtgagata gcaaattaga gcctcttgac tagtccagcc ccaagagttt
    16081 cctttaatta atactaatgt tgcggtgaac aaggcaatgg ttgaaaaaat taatcctccc
    16141 caatcaatct tagctttaac tgtcttttct tgttttaaag gaagtaagaa tacacaagcg
    16201 ataactccaa tcatacaaat ggggatatta acataaaaga cccaatgcca gtctaatttt
    16261 tctgttataa ttcccccaat tgttggacct aatgctgtag ataaaccttg tgttgcacct
    16321 aataaagtta gtgaaatcat tcttttctct gtaggcatta ttcctacccc tataaccata
    16381 ctaagtggaa taaggatagc tgcccccaga ctttgagtaa atctagctat gagtagaaaa
    16441 tttgcagaca tggataagcc acataataaa gaccctaaac caaatactat taatcctagt
    16501 aaataaaact tatttctccc aaacatatct gcaaacctag ccatgggtat ggcaaggact
    16561 gcaatagtca ttgtatagac attaagcatc caagaactcg tttctaacgt agtatgtaag
    16621 tcttcttgga tagcaggcaa ggtaatattc attattgtag aatcaatcat acatataaaa
    16681 attcctaaac acattaataa taaaattttt gtatggcttt tcttcctcat catttaatta
    16741 cctttactca ttaattgctg taattctctt tctatccaaa ccaaggtaaa ctttgcttca
    16801 tcaattccat aaagaagtgt aattttctta tgacgttcca tattaggata tttctcatta
    16861 agagatgtca aattgtctaa ttgtgcttga gctttttgtt tctctgtatt taaccattct
    16921 ttaattttat cgaagcttgt atattgtcca aaaaatatac gtattagcaa atccgatcga
    16981 attaacgtag gatttaaggg actattcata tattcctgaa attctttttc tccttttgag
    17041 gtaatgacat atagattctt attaggtttt ccttcttgtt gaataacttc cttttcaata
    17101 agctcatctt tttccattct tcgaagtgcc ggataaatgg ccccataaga agcttcaaaa
    17161 aagtatgaaa ccgaattttc catcatttgt ttaatatcat agccactcat tggtttttca
    17221 gctagaaaac ctaaaataac attttgtata ttcattttca ttccaccttt atattaacat
    17281 tgtttatatg tataatatta atataaacaa tgttaatata gacgtcaatg gattttttca
    17341 ccacagttag taaaagtaat tgatgtataa atatctgcct ttttatgcat ttgtttgtct
    17401 ttttagaaag ctataaaagt cactaaatca acgatgtata aaatcgtgta taaatgataa
    17461 atgtaaaaag cgaacgagcc cttttgtatc aaggactcgt ttttttgatg tcttccggaa
    17521 agaggtatta tgttaacttg ttttgtatat cgtatacaag tagaaaatat attataaagg
    17581 gatatggact tctctcatcc aactacttgt tttagactta acagtaatta actgattgct
    17641 tttccatttc aattccccta ggaatctaga atatacagct tcatttccaa cctcttctac
    17701 tagtaattca ttaattattc ttaagcctct ttcattgtaa acttcgcacc ataattgaaa
    17761 tccagaatat ctatgtactc ccttcaacat tgctaaaagt ttgcgatttg ggcttttctt
    17821 tggcgttttt gcagctataa aaatggcttc ataatcttgt ctaactattt cttctagagc
    17881 ttcttctaca tatttctgta tagttactaa agaaaaagaa gagtactttt ccaaagtagg
    17941 cactatatat tttctaacta tgttacaaaa tgcttgatat ttttcttcaa ctgactccaa
    18001 ttctataaat aacatataat catctggaag aagtatttcg acctcatgga tagccttctc
    18061 ttctgagtat gatacatcct tattgggatt agctaaacaa tatacagcaa tgctgttaag
    18121 ttcgtctaat tcgaatccta gatcctttaa tttcctacaa aaaatcaatt cgaaaactct
    18181 aagcccgtgt atattattat gatgtttttt aggtcttttt ttcgcccaat ccataatatg
    18241 aatatcaaac atttaaatgg tatcccttct tgtttataaa taaaaattaa atattactta
    18301 actaactacc attttaaaca ttaattttag aaatgctacc gataactgtg actatgttaa
    18361 ctaaaagtat atagaggata cacatatctt ttatagtgaa ccttgtgtaa acagtggtaa
    18421 gataaagctc tacataacaa gaaaaggtgg agtttaatat aaggaaacta actatattgg
    18481 atgaattaaa aaagcttaat gatgatttgt atcatccatt tcctcatgaa gacatttgta
    18541 aaatacaaga taaatttagt gtgaaattac atgaagacga cctgttaacc gcagacttta
    18601 atagctattg gatgaatatt gctggcagtt taagttatat gttaaaaggt aaaaccaaga
    18661 aaattcctcg aaatcagatc gatgaattaa agttaacttt ttttgaagcc tttccccaat
    18721 attctttttt agaagaagag atttctacct atccaaattt gtatgaagaa tataaggttt
    18781 atgagaaagc aagagagctc atgttaagtt atttatttaa ttaaagcgag taaagcaaaa
    18841 gagacgactt tctaaaaagc cgcctctttt tttgtggata aactacatta cgtgaactaa
    18901 ggttgtatat atatggttaa ataatcacaa tttttcataa aatggaaata tatttatttg
    18961 aaaataggat aatgaataaa gaggaatata tcaatgcttg gagatacttt tacacttttt
    19021 agaccggttt attatttaat aactcttctt ttagtatgta acttcgtata tgtagttttt
    19081 taaacaataa aattagagca actagctata tattattcaa ttccttattt tttgtaataa
    19141 ttgcagcagt tttattgttt caagaaggga taattgggga tgaaacaaac ttagcaggag
    19201 atccgttaac ttttgattta acaatatttt ttgggtttta cttatagcta gcttcatttt
    19261 tagaaataga aagaagagga aagcttaaaa tttcctctcc tttgtgttgt taccgataaa
    19321 aggttttatt aaaattcagt gtgaataata gcatacctag catgagaaag actagaatta
    19381 gaacaaatga gctcatcatt agtcctttct cttgtttttc aaaagctatt actccacatg
    19441 taaagcctgc aagataaata atggctccta cacaaagaat atttgaacta tatattgatg
    19501 tgaaatattg tcccaaccca ataaaaatac caagcagcga taaccacaat gaatatagac
    19561 taaagcgttt ttttaatata ttcctccaag aattaatcaa aagtaaataa tgttcccgtg
    19621 tttatggaaa ccttgttgaa gaaagtcttg gaggaaacac ctattaattc cttttgaacc
    19681 atcttctttt ataaagaaca taaaaaataa taaatctgcc caaacgtacg tatccagtat
    19741 taaaatactt tgttacgatt tgtcttgacc aagaggttga ttatatagat tgtgcagtag
    19801 atagagagga gaacgatatg tcaaaactgt tgtataaaat aggtggctgg tctggcagaa
    19861 ataaatttaa agtcctcggt ggttggataa ttataatgat tgccatccta ggaattgctt
    19921 tttccatgaa accagcgttc agtgaggaga tgaccatccc aggaacagct tctgaaaaag
    19981 ctgctgatat catttctgaa gaatttccat ctacacctga tgtggggtcg atacggatga
    20041 ttttcggtgc tggggagaac cagaaactta attcgaaaga ggctcaaaaa gctatctcgg
    20101 atgcacttgc taaaatctcg cgggataaat cagtaaaatc tatttcaaat ccttatgaag
    20161 taggcaccat caatcgtgag ggcactgttg cctatgctga tattacttat aaagaaaaag
    20221 ctgaaaatat aactaaaaaa tctaaagaac tagtaaaaga tagtgccaag atgacagaac
    20281 atcaaggtat tcaaacagaa ttaagtggag acattacagc ttttaaactt gagattggcg
    20341 gcatatctga agtaatcgga atcgttatgg cattcatcgt gttggtcgtc atgttcactt
    20401 catttttgat agcaggatta ccgattttca cagcgttgat tggattagct acaagcctag
    20461 gaattacatt cttagctact aatttctttg atatctcttc agtaagtatg acgctagcca
    20521 ttatgattgg tttagcagtc ggtatagatt atgcattatt tattttcact aaacataggc
    20581 aacagctgtc ggaagacatg gatattcatg aatcaattgc ccgagcaacg ggaacagctg
    20641 gaggagctgt tgtatttgct ggtttgacgg taatggtagc gctctttggt ttaacagtag
    20701 ttggcgtacc attt
//
