LOCUS       NZ_CP064270            20897 bp    DNA     circular CON 17-APR-2024
DEFINITION  Priestia megaterium strain N447-3 chromosome, complete genome.
ACCESSION   NZ_CP064270
VERSION     NZ_CP064270.1
KEYWORDS    RefSeq.
SOURCE      Priestia megaterium (Bacillus megaterium)
  ORGANISM  Priestia megaterium
            Bacteria; Bacillota; Bacilli; Bacillales; Bacillaceae; Priestia.
REFERENCE   1  (bases 1 to 5080837)
  AUTHORS   Wang,C., Jia,Z., Zhao,J., Wang,X., Liu,Z. and Ji,F.
  TITLE     Comparative Genome Analysis of key enzyme genes in ammonia nitrogen
            Metabolism Pathway of bacteria from different sources
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 5080837)
  AUTHORS   Wang,C., Jia,Z., Zhao,J., Wang,X., Liu,Z. and Ji,F.
  TITLE     Direct Submission
  JOURNAL   Submitted (29-OCT-2020) Guangdong Key Laboratory of Animal
            Conservation and Resource Utilization, Guangdong Public Laboratory
            of Wild Animal Conservation and Utilization, Institute of Zoology,
            Guangdong Academy of Science, Microbial Pathogenic Ecology Group,
            105 Xingang West Road, Guangzhou 510260, China
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: Canu v. V1.5
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 331.67x
            Sequencing Technology             :: Oxford Nanopore
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_022811865.1-RS_2024_04_17
            Annotation Date                   :: 04/17/2024 10:21:34
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 5,644
            CDSs (total)                      :: 5,465
            Genes (coding)                    :: 5,410
            CDSs (with protein)               :: 5,410
            Genes (RNA)                       :: 179
            rRNAs                             :: 14, 14, 14 (5S, 16S, 23S)
            complete rRNAs                    :: 14, 14, 14 (5S, 16S, 23S)
            tRNAs                             :: 131
            ncRNAs                            :: 6
            Pseudo Genes (total)              :: 55
            CDSs (without protein)            :: 55
            Pseudo Genes (ambiguous residues) :: 0 of 55
            Pseudo Genes (frameshifted)       :: 17 of 55
            Pseudo Genes (incomplete)         :: 32 of 55
            Pseudo Genes (internal stop)      :: 11 of 55
            Pseudo Genes (multiple problems)  :: 5 of 55
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 08:04:25
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 4083043
            Orig. end                         :: 4103940
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP064270.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..20897
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene-precursor"
                     /region_number="6"
                     /rules="(PT_FPPS_like and not PT_HPP)"
                     /tool="antismash"
     cand_cluster    1..20897
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_FPPS_like and not PT_HPP)"
                     /kind="single"
                     /product="terpene-precursor"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..20897
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:10897](+)"
                     /cutoff="10000"
                     /detection_rule="(PT_FPPS_like and not PT_HPP)"
                     /neighbourhood="10000"
                     /product="terpene-precursor"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..10897
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="(PT_FPPS_like and not PT_HPP)"
                     /neighbourhood="10000"
                     /product="terpene-precursor"
                     /protocluster_number="1"
     gene            779..1291
                     /gene="spoIIIAB"
                     /locus_tag="IQ863_RS21115"
     CDS             779..1291
                     /GO_function="GO:0003674 - molecular_function [Evidence
                     IEA]"
                     /GO_process="GO:0030436 - asexual sporulation [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="spoIIIAB"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013084997.1"
                     /locus_tag="IQ863_RS21115"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="stage III sporulation protein SpoIIIAB"
                     /protein_id="WP_013059152.1"
                     /transl_table=11
                     /translation="MKLFGAIFILFASTYTGFEFAKQLSARPRQLRQLKTALRSLEAEI
                     MYSNRPLQEVAHLLSLQLPNPLASLFNEFSMKLKEGTESVKEAWEKTLDQFWKQTALKT
                     GELEILKQFGETLGQHDRYSQQKHILLTLNHLEREEQDAVDKQNRYEKMVKSLGFLSGL
                     LLVILLM"
     gene            1311..1517
                     /gene="spoIIIAC"
                     /locus_tag="IQ863_RS21120"
     CDS             1311..1517
                     /GO_function="GO:0003674 - molecular_function [Evidence
                     IEA]"
                     /GO_process="GO:0030436 - asexual sporulation [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="spoIIIAC"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_390321.1"
                     /locus_tag="IQ863_RS21120"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="stage III sporulation protein AC"
                     /protein_id="WP_013059151.1"
                     /transl_table=11
                     /translation="MGIDMNTIFQIAGIGIVVAFLVTVLEQMGKKDYANWVTLIGFIYI
                     LFMVASIVEDLFQKIKSVFLFQG"
     gene            1538..1921
                     /gene="spoIIIAD"
                     /locus_tag="IQ863_RS21125"
     CDS             1538..1921
                     /GO_function="GO:0003674 - molecular_function [Evidence
                     IEA]"
                     /GO_process="GO:0030436 - asexual sporulation [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="spoIIIAD"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013059150.1"
                     /locus_tag="IQ863_RS21125"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="stage III sporulation protein AD"
                     /protein_id="WP_013059150.1"
                     /transl_table=11
                     /translation="MLQIVGLGLVATFLALILKEHKSPIAFLLVVFVGSVIFLFLIDQI
                     YEIIKMVERLSINAHVNMIYVETILKIIGIAYIAEFGAQITKDAGQGAIASKIELGGKV
                     LILSMAIPILTVIIETIISMLPN"
     gene            1946..3130
                     /gene="spoIIIAE"
                     /locus_tag="IQ863_RS21130"
     CDS             1946..3130
                     /GO_function="GO:0003674 - molecular_function [Evidence
                     IEA]"
                     /GO_process="GO:0030436 - asexual sporulation [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="spoIIIAE"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013059149.1"
                     /locus_tag="IQ863_RS21130"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="stage III sporulation protein AE"
                     /protein_id="WP_013059149.1"
                     /transl_table=11
                     /translation="MKRWTFKVNILALLLFLFFFFPENVQASEPPKQQELVNEQIDKLG
                     IDEVKQFWDDIITQYGGFLPESQKGSLVDFLKGEKEFSLKEWLGGLVKFLFHEVLANGK
                     LLGTLIMLTVFSVFLQTLQSAFNQQTVSKVAYALVYMVLIIIALNSFQIAISYATGAIE
                     TMTKFILALVPLLLALMASSGGVVSAAFFHPMILFLMNTSGLLIQYVVMPLLFLSALLS
                     IVSTISDEHKVTQLAQLLRNISIGVLGIFLTVFLGVLSVQGATSAVADGITIRTAKFVT
                     GNFIPVVGRVFTDAADTVISASLLLKNSVGIAGVAVLLLIVAFPAIKVLTLAFIYKLAA
                     ALLQPIGGGPVISCLSIISKSVIYIFAALAVVSLMFFLCLTVIITASNVTMMVR"
     gene            3127..3756
                     /gene="spoIIIAF"
                     /locus_tag="IQ863_RS21135"
     CDS             3127..3756
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0003674 - molecular_function [Evidence
                     IEA]"
                     /GO_process="GO:0030436 - asexual sporulation [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="spoIIIAF"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013059148.1"
                     /locus_tag="IQ863_RS21135"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="stage III sporulation protein AF"
                     /protein_id="WP_226554901.1"
                     /transl_table=11
                     /translation="MKKLQALTTWITNIVLFILLATIINLLLPNSSFQKYTKLVVGLLL
                     MLIIITPVFQIFKVDVNQMLKSLSLSSIRSDQQVENSIENQKKEIQASQRAYILEQMAV
                     QMEADVKEELMDQYGVAIDRIHIETKKPNDEPTADNIKSISVAVSKKTSGDSEVVSAVK
                     VISIDTSTPIETNKPTESKKLSNYLAAKWDVKQGQVVVNMEEGDTK"
     gene            3753..4415
                     /gene="spoIIIAG"
                     /locus_tag="IQ863_RS21140"
     CDS             3753..4415
                     /GO_function="GO:0003674 - molecular_function [Evidence
                     IEA]"
                     /GO_process="GO:0030436 - asexual sporulation [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="spoIIIAG"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013084996.1"
                     /locus_tag="IQ863_RS21140"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="stage III sporulation protein AG"
                     /protein_id="WP_013084996.1"
                     /transl_table=11
                     /translation="MSQKPEKGDPSFFQRFFSLKQSSTTKKPSKLMYIGILLAAGVIFM
                     VFSNSLTTSMNSGGLLKSASKETSAPPVSQDVPAFSSKKTTTMTGYEERYEEELKDILD
                     QVRGVSKVKVIVNLDATESKIYEKNSVTKSQTTNETDREGGTRKVEDSSTDEQLVIVRS
                     GEQEKPVVVKTEKPKVRGVLVVAKGADNIEVKKSIIEAVTRALDIPSHRVAVLAKKG"
     gene            4423..5073
                     /locus_tag="IQ863_RS21145"
     CDS             4423..5073
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013059146.1"
                     /locus_tag="IQ863_RS21145"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="SpoIIIAH-like family protein"
                     /protein_id="WP_226554902.1"
                     /transl_table=11
                     /translation="MSMLLKKQTVWLLTMLSLVVVLSVYYMTTPENPQSNVALVDNEKQ
                     SEKQADDKTPAEDTKQQTDEKSGTKEDSKTEGSAEDVKKETAKNAKESAVVSSTDSDEL
                     FTALRLELNDERSQLKEEYQEVAASKNVTPAEVSKAMDKIDELSKLGEKEATLETLIKA
                     KGYSDALVRADGKQVQITVKTEKHSKTKANQIIQLVKKEMGPKEVAVEFQPTK"
     gene            5426..5929
                     /gene="accB"
                     /locus_tag="IQ863_RS21150"
     CDS             5426..5929
                     /EC_number="6.4.1.2"
                     /GO_component="GO:0009317 - acetyl-CoA carboxylase complex
                     [Evidence IEA]"
                     /GO_function="GO:0003989 - acetyl-CoA carboxylase activity
                     [Evidence IEA]"
                     /GO_process="GO:0006633 - fatty acid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="accB"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008358617.1"
                     /locus_tag="IQ863_RS21150"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="acetyl-CoA carboxylase biotin carboxyl carrier
                     protein"
                     /protein_id="WP_243555965.1"
                     /transl_table=11
                     /translation="MLKIQEIREIIKLVDQSSIEEFTYEHEGSKIKMKKKDAIVSKQAQ
                     QVVVSAPEQAAPAPQAAAAPAPAPAAQSAQPKEEQAAPAVDESLHKITSPMVGTFYASS
                     SPESDVYVTPGDKVQKDSVVCIVEAMKLFNEIEAEVKGEIVDVLVENGQLVEYGQPLFL
                     VKPE"
     gene            5942..7294
                     /gene="accC"
                     /locus_tag="IQ863_RS21155"
     CDS             5942..7294
                     /EC_number="6.3.4.14"
                     /GO_component="GO:0009317 - acetyl-CoA carboxylase complex
                     [Evidence IEA]"
                     /GO_function="GO:0003989 - acetyl-CoA carboxylase activity
                     [Evidence IEA]"
                     /GO_function="GO:0004075 - biotin carboxylase activity
                     [Evidence IEA]"
                     /GO_process="GO:0006633 - fatty acid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="accC"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) RimK"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ATP-grasp"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Dala_Dala_lig_C"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ATP-grasp_3"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1090: acetyl-CoA carboxylase biotin carboxylase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003394136.1"
                     /locus_tag="IQ863_RS21155"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="acetyl-CoA carboxylase biotin carboxylase
                     subunit"
                     /protein_id="WP_013084993.1"
                     /sec_met_domain="RimK (E-value: 7.9e-06, bitscore: 23.8,
                     seeds: 4, tool: rule-based-clusters)"
                     /sec_met_domain="ATP-grasp (E-value: 5.3e-07, bitscore:
                     27.6, seeds: 20, tool: rule-based-clusters)"
                     /sec_met_domain="Dala_Dala_lig_C (E-value: 8.6e-10,
                     bitscore: 36.7, seeds: 12, tool: rule-based-clusters)"
                     /sec_met_domain="ATP-grasp_3 (E-value: 5.4e-06, bitscore:
                     24.8, seeds: 15, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIKKLLIANRGEIAVRIIRACKELGVESVAVHSQADRDSLHVQLA
                     DEAYCIGPTSSKDSYLNFTNIMSVAMLTGCDAIHPGYGFLAENADFAELCRECNVTFVG
                     PSPEAINKMGTKDVARETMREAGVPIVPGSTGIVESVEDGMSIANDIGYPVIIKATAGG
                     GGKGIRVAKNEQELIKGITITQQEAATAFGNPGVYIEKFIEDFRHVEIQVLADSHGNTV
                     HLGERDCSIQRRLQKLIEETPSPALDEKTRELMGDAAVKAAQAVNYTGAGTVEFIYDYR
                     ENKFYFMEMNTRIQVEHPVTEMVTGVDLIKEQIKVANGETLPFTQEEVTFNGWAIECRI
                     NAENPEKNFMPSPGTIQMYLPPGGYGVRVDSAAYPGYAIPPYYDSMVAKLIVHAPTREE
                     AIERMKRALDEFVIDGVATTIPFHQKLLNHEKFVSGEFNTKFLELYDVMNS"
     gene            7324..7725
                     /locus_tag="IQ863_RS21160"
     CDS             7324..7725
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013059143.1"
                     /locus_tag="IQ863_RS21160"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="WP_013059143.1"
                     /transl_table=11
                     /translation="MNENHVLEMEEHPNSLGKVEIAPEVIEVIAGIAASEVEGVSAMRG
                     NFAAGVVEKLGKKNHGKGVKVDLTENGIKVDVFCMMKFGVSIPNVAQQVQDNIRQALKN
                     MTAIDLDEVNIHIVGIQFDTQKTDIEEVE"
     gene            7947..8339
                     /gene="nusB"
                     /locus_tag="IQ863_RS21165"
     CDS             7947..8339
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene="nusB"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013059142.1"
                     /locus_tag="IQ863_RS21165"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="transcription antitermination factor NusB"
                     /protein_id="WP_013059142.1"
                     /transl_table=11
                     /translation="MKRHTARQKALQALFQHDLGQTEPMEAIGNVVQNEKSDQFLESLV
                     LGVVEHQQEIDELLRNHLEKWTLDRVATVDRVILRIAVYEMKYEEEIPTSVTLNEAIEL
                     AKTFGDDQSSKFINGVLSKVLTTLSK"
     gene            8424..9764
                     /gene="xseA"
                     /locus_tag="IQ863_RS21170"
     CDS             8424..9764
                     /EC_number="3.1.11.6"
                     /GO_component="GO:0009318 - exodeoxyribonuclease VII
                     complex [Evidence IEA]"
                     /GO_function="GO:0008855 - exodeoxyribonuclease VII
                     activity [Evidence IEA]"
                     /GO_process="GO:0006308 - DNA catabolic process [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="xseA"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013084992.1"
                     /locus_tag="IQ863_RS21170"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="exodeoxyribonuclease VII large subunit"
                     /protein_id="WP_014458246.1"
                     /transl_table=11
                     /translation="MGEVRYLTVTALTRYIKRKFDVDPHMQDVWIKGEISNFKRHSRGH
                     MYFTLKDQNARIAAVMFAGHNRQLNFQPEEGMNVLIRAEISVYEPSGNYQMYVKEMQPD
                     GVGNLYLAYEQLKKKLEKEGLFDPARKRKLPKYPTTIGVITSPTGAAVRDIITTLKRRY
                     NANIIVMPALVQGVNAAPSIIKAIEEANRRKEADVLIVGRGGGSIEELWAFNEESVARA
                     IFTSTIPVISAVGHETDFTIADFVADLRAPTPTGAAELAVPHISEITERLTQRNIRLLR
                     SMKEMLQSSSRRLERSQKSYAFRYPQKLVEQKEQQLDQLMERFYREGRRYIEHKRTNYE
                     QLTAALLRNHPEHQLMKAAERQQQLTKMLTKEMQQLLKQKQLLFATATSKLHTLSPLKT
                     MERGYSLVYDKEKELIKSTKQVSKGDVVNVRLTDGQLQCEVSKIEER"
     misc_feature    8471..8484
                     /note="TFBS match to PsrA, Oleic acid responsive regulator,
                     confidence: weak, score: 19.99"
                     /tool="antismash"
     gene            9768..10001
                     /locus_tag="IQ863_RS21175"
     CDS             9768..10001
                     /EC_number="3.1.11.6"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013059140.1"
                     /locus_tag="IQ863_RS21175"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="exodeoxyribonuclease VII small subunit"
                     /protein_id="WP_013059140.1"
                     /transl_table=11
                     /translation="MATNKEYTFEEAMEQLETIVNKLEEGDVPLEEAIQQFQEGMTLSK
                     FCHDRLQHIEKQMETILREDGTLEPFSVQEEE"
     gene            10001..10897
                     /locus_tag="IQ863_RS21180"
     CDS             10001..10897
                     /GO_process="GO:0008299 - isoprenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene-precursor: PT_FPPS_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1182: Polyprenyl synthetase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014458247.1"
                     /locus_tag="IQ863_RS21180"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="polyprenyl synthetase family protein"
                     /protein_id="WP_243555967.1"
                     /sec_met_domain="PT_FPPS_like (E-value: 8.4e-64, bitscore:
                     213.7, seeds: 145, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MVNEMNLKEYISFTKDRVETRLPEVVKALHAPVNLKESMLYSLTA
                     GGKRLRPVLLFATLHAFGKDESMGLETACAVEMIHTYSLIHDDLPSMDDDDLRRGKPTN
                     HKVYGEATAILAGDALLTNSFQLISEAAHPEITSHMKLQLITELVKASGTEGMISGQVA
                     DMEGEKKQLTLDELEYIHLHKTGKLLEFCVKAGAILAKATPLQQKLLEEFSKHVGLAFQ
                     IQDDILDVEGSEEKLGKPIGSDTENEKTTYPSLLGMEAAKEKLQYHVEQALLSLRQAQI
                     KHGLLEEICLYIAKRDS"
     misc_feature    10979..10997
                     /note="TFBS match to LexA_variant_3, Repressor of DNA
                     damage response, confidence: weak, score: 23.65"
                     /tool="antismash"
     misc_feature    11179..11195
                     /note="TFBS match to HexR, Glucose-responsive regulator,
                     confidence: weak, score: 23.34"
                     /tool="antismash"
     gene            11218..13119
                     /gene="dxs"
                     /locus_tag="IQ863_RS21185"
     CDS             11218..13119
                     /EC_number="2.2.1.7"
                     /GO_component="GO:0005737 - cytoplasm [Evidence IEA]"
                     /GO_function="GO:0008661 - 1-deoxy-D-xylulose-5-phosphate
                     synthase activity [Evidence IEA]"
                     /GO_process="GO:0008615 - pyridoxine biosynthetic process
                     [Evidence IEA]"
                     /GO_process="GO:0009228 - thiamine biosynthetic process
                     [Evidence IEA]"
                     /GO_process="GO:0009240 - isopentenyl diphosphate
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /gene="dxs"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) DXP_synthase_N"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) TPP_enzyme_C"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1110: 1-deoxy-D-xylulose-5-phosphate synthase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013084989.1"
                     /locus_tag="IQ863_RS21185"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="1-deoxy-D-xylulose-5-phosphate synthase"
                     /protein_id="WP_014458248.1"
                     /sec_met_domain="DXP_synthase_N (E-value: 2.3e-119,
                     bitscore: 395.8, seeds: 174, tool: rule-based-clusters)"
                     /sec_met_domain="TPP_enzyme_C (E-value: 1.1e-05, bitscore:
                     23.5, seeds: 323, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDLTTIKNPEFLKKMSVTQLEELSEEIRRFLITKLSATGGHIGPN
                     LGVVELTLALHKVFDSPKDKFLWDVGHQSYVHKILTGRAGEFDTIRQYKGLCGFPKRDE
                     SEHDVWETGHSSTSLSAAMGMAAARDLQKTKAHIVPIIGDGALTGGMALEALNHIGHEQ
                     TDMTVILNDNEMSIAPNVGAVHSILGRLRTAGKYNWVKDELEVLLKKVPAVGGKLAATA
                     ERVKDGLKYMVVSGMFFEDLGFTYLGPVDGHSYDDLLETLQYAKKTKGPVLIHVITKKG
                     KGYLPAESDKSGAWHGTGPYKIESGDFIKDKNVPIAWSKLVSDTVLKMAREDERIVAVT
                     PAMPVGSKLEAFQKEFPHRMFDVGIAEQHATTMAAGLATQNMKPFLAIYSTFLQRAYDQ
                     VVHDICRQKLNVFIGIDRAGLVGADGETHQGVFDIAFLRHLPNLVIMMPKDENEGQHMV
                     HTALTYEEGPIAMRYARGNGLGVELDSELKNIPIGTWDVLKEGSDTTILTFGTTISMAM
                     DAAAELEKQGISVKVVNARFIKPLDEKMLHEIFQTSKPVITVEEAVLQGGFGSAVLEFA
                     SEHGYYDTRVERMGIPDRFIEHGSVTKLLEEIGLTKEEIINRVKKLVTPTQKRLEVK"
     gene            13116..13943
                     /locus_tag="IQ863_RS21190"
     CDS             13116..13943
                     /GO_function="GO:0008168 - methyltransferase activity
                     [Evidence IEA]"
                     /GO_process="GO:0032259 - methylation [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014458249.1"
                     /locus_tag="IQ863_RS21190"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="TlyA family RNA methyltransferase"
                     /protein_id="WP_014458249.1"
                     /transl_table=11
                     /translation="MTKKERVDVLLVERGLIETREKAKRTVMAGLVYANEVRLDKPGEK
                     IERDTPLTIKGAVMPYVSRGGFKLEKAIKEFNVHVADKIMIDIGSSTGGFTDCALQNGA
                     KMSYALDVGYNQLAWKLRQDERVEVMERTNFRYVTPADLSRGLPEFASIDVSFISLRLI
                     LPVLKTLLVPHSDVVALVKPQFEAGREQVGKKGIVRDSKVHEEVLQGMVDFSLRQGYDV
                     YNMSYSPITGGDGNIEFLLHLRWKGERELGENQAPLTVHEVVEEAHKTLKEKK"
     misc_feature    13964..13984
                     /note="TFBS match to MntR, Manganese transport regulator,
                     confidence: weak, score: 26.6"
                     /tool="antismash"
     gene            14105..14554
                     /gene="argR"
                     /locus_tag="IQ863_RS21195"
     CDS             14105..14554
                     /codon_start=1
                     /gene="argR"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017150893.1"
                     /locus_tag="IQ863_RS21195"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="transcriptional regulator ArgR"
                     /protein_id="WP_013059136.1"
                     /transl_table=11
                     /translation="MNKGQRHIKIRDIITNNDIETQDELVDILKNQGFNVTQATISRDI
                     KELHLVKVPLMDGRYKYSLPADQRFNPLQKLKRSLMDAFVKIDSAGHMLVMKTLPGNAN
                     AIGALIDHLDWDEILGTICGDDTCLIICRTPEDTQIISDRFLEML"
     gene            14571..16298
                     /gene="recN"
                     /locus_tag="IQ863_RS21200"
     CDS             14571..16298
                     /GO_component="GO:0005737 - cytoplasm [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_process="GO:0006281 - DNA repair [Evidence IEA]"
                     /GO_process="GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /gene="recN"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013059135.1"
                     /locus_tag="IQ863_RS21200"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="DNA repair protein RecN"
                     /protein_id="WP_014458250.1"
                     /transl_table=11
                     /translation="MLAELSIKNFAIIDELSVSFEKGLTVLTGETGAGKSIIIDAISLL
                     VGGRGSSEFVRHGTDRAEIEGLFLFDEEQHPSHEKAKQVGLEVEDGMIVLRRDITTNGK
                     SICRINGKLVTLAILREVGQTLIDIHGQHEHQDLMNQDRHLTLLDQYGGEKVEEALTEY
                     REVFSRYTSLKKQLDQLTENEQQMAHRLDLIQFQLDEIKAANLQLNEDEELNEERLKIS
                     NFEKIYTSLNDAYNALHGEHQGLDWVGVAMNHTEDISSLEKNYAEISEIISSSFYQLED
                     ASYKIRQQLDLLEFDPKRLDFIEARLNEINHLKRKYGQSVDEILEYAAQIEDEIDRIEN
                     RDTHVSKIKEQLNSVAQDLLVEANNVSAIRKKLAQELTDSIHHELQELYMAKTVFQIKF
                     SVVNAGKNDVEVNGERIKFTKDGIDNVAFYISTNPGEPLKPLAKVASGGELSRIMLALK
                     SIFSKHQGVTSIIFDEVDTGVSGRVAQSIGEKIHAISVDSQVLCISHLPQVAAMADTHL
                     FIAKEIKGDRTTTSVLPLTLDEKVKEIGRMIAGAEITSLTKEHAKELLDLADKMKQTI"
     gene            16482..17762
                     /gene="spoIVB"
                     /locus_tag="IQ863_RS21205"
     CDS             16482..17762
                     /EC_number="3.4.21.116"
                     /GO_function="GO:0008236 - serine-type peptidase activity
                     [Evidence IEA]"
                     /GO_process="GO:0030436 - asexual sporulation [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="spoIVB"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014458251.1"
                     /locus_tag="IQ863_RS21205"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="SpoIVB peptidase"
                     /protein_id="WP_014458251.1"
                     /transl_table=11
                     /translation="MQNLYRHIIGAILLVSFIFVGFIPVVQQYIHIPKQIVLFEQQKEK
                     INTTLPLSVEASSPVYDVTSNKAKLTVAGKQVGKEELMLHLAGIPVKRVDVQVLSDFKV
                     IPGGQSIGVKLNSKGVLVVGYHQVDTAKGKKSPGEIAGIQVGDMITKINGKTIEKMSDI
                     TPFIQQAGKTGEPLNLHILREKKQFDTKLYPLKDKQDYAYRIGLYIRDSAAGIGTMTFY
                     DPKSKKYGALGHVISDMDTKKPIVVEDGQIVRSTVTSIEKGSNGVPGEKLARFSEDRQI
                     IGNITRNSPFGIFGKLSSTMENGIMDKAMPIALSHQVKEGPAKILTVVDDDQVEEFDIE
                     IMSTIPQKFPATKGMVIKITDPKLLKKTGGIVQGMSGSPIIQNGKVVGAVTHVFVNDPT
                     SGYGVHIEWMLNEAGIDIYKNNRKKAS"
     misc_feature    17780..17793
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: medium, score: 22.15"
                     /tool="antismash"
     misc_feature    complement(17874..17887)
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: medium, score: 22.45"
                     /tool="antismash"
     gene            17990..18778
                     /gene="spo0A"
                     /locus_tag="IQ863_RS21210"
     CDS             17990..18778
                     /GO_function="GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA]"
                     /GO_process="GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /GO_process="GO:0030436 - asexual sporulation [Evidence
                     IEA]"
                     /GO_process="GO:0042173 - regulation of sporulation
                     resulting in formation of a cellular spore [Evidence IEA]"
                     /codon_start=1
                     /gene="spo0A"
                     /gene_functions="regulatory (smcogs) SMCOG1008: response
                     regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003153177.1"
                     /locus_tag="IQ863_RS21210"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="sporulation transcription factor Spo0A"
                     /protein_id="WP_013084985.1"
                     /transl_table=11
                     /translation="MKKIKVCLVDDNRELIGLLEDYISEQEDMEVIGVAYNGQECLSIL
                     KDKDPDVLVLDIIMPHLDGLAVLGQLKEMKKENYPNVIMLTAFGQEDVTKKAVDLGAAY
                     FILKPFDMENLVNHIRQVSGQTSSFMQRSSSSMRSHRDSKPANLDASITSIIHEIGVPA
                     HIKGYLYLREAISMVYKDIELLGSITKVLYPDIAKKYNTTASRVERAIRHAIEVAWSRG
                     NIDSISSLFGYTVSMSKAKPTNSEFIAMVADKLRLEHKAS"
     gene            18932..19903
                     /locus_tag="IQ863_RS21215"
     CDS             18932..19903
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0006310 - DNA recombination [Evidence IEA]"
                     /GO_process="GO:0015074 - DNA integration [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1077: phage integrase
                     family protein"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016109083.1"
                     /locus_tag="IQ863_RS21215"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="WP_243555969.1"
                     /transl_table=11
                     /translation="MSELHLQLDNFMLHCDSKGLSRKTLKSYEQTLRLFISFLENKHKV
                     TEAEKVRTVHIRAYILYLRKRGKYTVVADELSANLNHPTHRTDFSKPISDTTIANYLRN
                     IKVFFNLLYDENEITENPAKKVANIKPARKQKALLTEDEIVKVLRAFDITTFHGYRSWL
                     QVRLLLDTGIRSGECCSLQPENVDIKNRALLIENPKNNKQRYVYFSAKMANDLRRWLLY
                     RDRFSESEYLFPTTRGTMLDTNNFEKMLKQAGKRVGVAIHAHQLRNTFAKYYLLNGGDF
                     VTLSRLLGHSSVEVTQKAYLDFAENEVARKYQRHSPLNKMNL"
     misc_feature    complement(20026..20039)
                     /note="TFBS match to LexA_variant_2, Repressor of DNA
                     damage response, confidence: medium, score: 21.84"
                     /tool="antismash"
     gene            20072..20854
                     /locus_tag="IQ863_RS21220"
     CDS             20072..20854
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010333795.1"
                     /locus_tag="IQ863_RS21220"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="WP_243555971.1"
                     /transl_table=11
                     /translation="MYQELAKQHRTFDNVEHLNYAVRKHLYHNKHQLSQTAIDVFKLLA
                     RHAVKYVGVAYLKIETIAKAIDKHRSTVMRALKVLAELNIIEKLTQYRPKTGGNGANIY
                     VIQRYKPMQGEVKNSAENTNATPSVQLRNEAENTVVASVDSPKTVTETEIPESINKVLK
                     RIRSITPYSEFKNWVNAYVKDNKLTNKLYGIYKAQTHYIKGVYGAELLLHVGIQAIKTT
                     FTATKRKNIKSLTGYFNGVLDKLLDRLYYSTIGQPCII"
ORIGIN
        1 tttgtttatc ttaaataaat taagccagtt ttcgatttat atgattgaag aagaattgaa
       61 aaaaggatat gtcaccattg aaggcgggca ccgggttgga ctagcgggaa aagtcgtaac
      121 ggaaaatgga caggttcgtg tgattcgaga tgtatcatcc tttaatatcc ggattgctaa
      181 acaaaagata ggtatttcga atcgacttat tcctttttta tacaatcgct attggcaaag
      241 tacggtcatt ataggacctc ctcaaacagg aaaaacaacc atgattcgcg atttagccag
      301 agtaataagt actggcatag agcgctctaa aattcctccg tttaaagtgg gaattgtgga
      361 tgaacgatca gaaattgctg gggctgttaa aggggttcct cagcatacat tcggatctag
      421 aatggattta ttagatagct gtccgaaagc tgaaggcatg atgatgatga ttcgctctat
      481 gagtcccgat gtgctgatcg tggatgaagt tggaagtgaa gaagattgta aagccgtact
      541 tgaagccgtt aatgctggcg ttcgtgtcat tatgaccgtt catgggtatg acattgacga
      601 tttaatgaag cgtcccactt tgcaagcttt aatgaaactt cacgtattca aaaggtatgt
      661 tgtgctatcg aacagccgag gtcctggaac acttcaggct atctacgatg agcactataa
      721 ttccatgaaa acgtccgctg aaaagtcgct tattgaaaat agtaaagggt gatggtgtat
      781 gaaactgttt ggtgccatct ttatcttatt tgcttccact tacacaggat ttgagtttgc
      841 aaagcagctt agtgcaagac ctaggcagct caggcaatta aaaacggctc tgaggtcgtt
      901 agaagcagaa attatgtaca gcaatcggcc tcttcaagaa gttgctcatt tgttatctct
      961 acagcttcct aatcctttgg cttctttatt taatgagttt tcaatgaaat taaaagaagg
     1021 tactgaaagt gtcaaggaag cttgggaaaa gacgttggac caattttgga aacaaaccgc
     1081 acttaaaacg ggagaactag aaatcttaaa acaatttggt gaaacgcttg gtcagcatga
     1141 tcgttattcg cagcaaaagc atatcttact gacgctgaat catcttgaac gcgaagaaca
     1201 agatgcagtt gataagcaga atcgctatga aaaaatggtt aaaagtttag gctttctatc
     1261 tggattgcta ctggtcattc tattgatgta gcgatggagg aggattgaat gtgggaattg
     1321 atatgaacac catttttcag attgctggga ttggtatcgt cgtagctttt ttagtcaccg
     1381 tactcgaaca gatgggaaaa aaagattacg cgaactgggt tacgctcatc ggttttattt
     1441 atattttatt tatggttgct tcgattgtag aggacttatt tcagaaaatc aaatcggttt
     1501 ttttatttca agggtagagg ggtgagttgc cattgaaatg cttcaaattg tgggcttagg
     1561 attagtagct acgtttttgg ctcttatttt aaaagaacat aaatcaccta ttgctttttt
     1621 acttgttgta ttcgtgggat ccgtgatctt tcttttttta attgatcaaa tctacgagat
     1681 tattaagatg gtcgagcggc tgtcgatcaa tgcccacgtt aacatgattt atgtggaaac
     1741 cattttgaaa atcattggta ttgcctatat tgccgaattt ggtgctcaaa ttacgaaaga
     1801 tgcaggacaa ggtgcgattg cttctaaaat tgaattaggt ggaaaagtgc tgattctctc
     1861 catggcaatt cctattttga cggtcattat tgaaacgatt atttcaatgc tgcccaatta
     1921 attttactta atatgaggtg acgaaatgaa gcggtggacg tttaaagtga atatactcgc
     1981 tcttcttttg ttcctctttt ttttctttcc agaaaatgta caagcttccg aacccccgaa
     2041 gcagcaagaa cttgtcaatg aacaaattga taagctcggt atcgatgaag tcaaacagtt
     2101 ttgggacgat attattaccc aatacggcgg ctttttaccc gagagtcaga agggaagttt
     2161 agtcgatttt ttaaaaggag aaaaagagtt ctctcttaaa gaatggctag gaggtcttgt
     2221 aaagttttta tttcacgaag tattagcgaa tggaaagctc ctcggtacgc tcattatgct
     2281 aacggttttt agcgtgtttt tgcaaacgct ccaaagtgcg tttaatcagc aaaccgtaag
     2341 taaagtagcg tatgcgcttg tatatatggt tttgatcatc attgctctta atagttttca
     2401 aattgctatc tcttatgcaa cgggagcgat tgagactatg actaaattca ttttagctct
     2461 ggtgccgctg ctgcttgcct taatggcatc atcaggggga gttgtatcgg cagccttttt
     2521 tcatccgatg attttgtttt taatgaacac aagcggcttg cttattcaat acgtagtgat
     2581 gccgctgctt tttctttcag cactgcttag cattgtgagt acgatttcag atgaacataa
     2641 ggttacacag cttgctcagc tgttgagaaa tataagcatt ggcgtgcttg gaatattcct
     2701 aaccgttttt ttaggagtgc tatccgttca aggggccacg tcagctgttg cggacggtat
     2761 tacgattcga acggcaaagt ttgtcacagg gaactttata cctgttgtag ggcgtgtgtt
     2821 cacagatgcg gctgatacag tcatcagtgc ctcgcttcta ttaaagaatt cagtagggat
     2881 tgctggagta gcagtcttac tgttaatcgt cgcgtttccg gctattaaag tgttaacgct
     2941 cgcttttatc tataagttag cagcagctct tcttcaaccc attggaggag gaccggttat
     3001 ttcctgcttg agcattatca gcaaaagcgt catctatatt tttgcggcgc ttgcggttgt
     3061 ctcgcttatg tttttcttat gtttaacggt catcatcaca gcgagcaacg tcacaatgat
     3121 ggtgaggtga agaaattgca ggccttaacg acgtggatta ctaatatcgt tctttttatc
     3181 ttattagcta ccattattaa tttactgttg cccaattcta gttttcaaaa gtatacgaag
     3241 ctggtggttg gacttctttt gatgctgatt attattacac ccgtttttca aatttttaaa
     3301 gtggatgtta atcaaatgct aaaatcactt agtttatcat ctattcgatc cgatcagcag
     3361 gtagaaaatt caatagaaaa tcagaaaaaa gaaatacaag cttcacaacg tgcatatatt
     3421 ttagaacaaa tggctgtcca aatggaggca gatgtaaaag aggagttgat ggatcagtat
     3481 ggtgtagcaa ttgatcgaat tcacattgaa acaaaaaagc cgaacgacga acctaccgct
     3541 gataatatta aatccatttc agttgccgta agtaaaaaaa catcgggtga ttccgaggtt
     3601 gtttcagctg tgaaagttat ttctattgat acctccacac cgatcgaaac aaacaaacca
     3661 acagaatcca agaaattatc caactattta gcagcaaaat gggatgtaaa acaaggccaa
     3721 gttgttgtga atatggagga gggagacacg aaatgagtca aaagccagaa aaaggtgacc
     3781 catcattttt tcagcggttc ttttcactta aacagtcatc aactacgaag aaaccttcaa
     3841 agttaatgta tataggcatt ttactagctg caggcgttat ctttatggta tttagcaact
     3901 cactcacaac atctatgaat tcaggcggat tactaaagag tgcaagcaaa gaaaccagcg
     3961 caccaccggt atcacaggat gttcccgctt ttagctctaa aaagacaaca acaatgacgg
     4021 gctatgaaga gcggtatgag gaagaattga aagatatttt agaccaagtt agaggcgtca
     4081 gtaaggtaaa agtaattgtg aacttagatg caacagaatc caaaatatat gaaaaaaaca
     4141 gcgtcacaaa atcgcaaacg accaatgaaa cagaccgtga aggaggaact cgtaaagttg
     4201 aagattcctc aacagatgaa cagctggtca ttgtaagaag tggagaacaa gaaaagcctg
     4261 ttgtagtcaa aaccgaaaag ccaaaagtac gaggtgtgtt agttgtcgct aaaggagctg
     4321 ataatatcga ggtaaaaaaa tctatcattg aagctgtgac aagagcgctc gatataccaa
     4381 gtcatagagt agcagtatta gcgaaaaaag gatgaggggg aaatgagtat gttattaaaa
     4441 aagcaaacag tttggttatt aacgatgtta agtttagttg ttgtgttatc ggtgtactat
     4501 atgacaacgc cagaaaatcc tcagagtaat gttgcgctag tagacaatga aaaacaaagc
     4561 gaaaagcagg ctgatgacaa gactcctgca gaagatacaa aacaacagac agatgagaaa
     4621 tcaggaacaa aagaagattc aaaaactgaa ggctcagcag aagatgtaaa gaaggaaacg
     4681 gctaaaaatg caaaagaatc agcggttgta tcaagcacag atagcgacga gctatttacg
     4741 gcgcttcgtt tggaattaaa tgatgaaaga agtcaattaa aagaagagta tcaggaagta
     4801 gcggcatcaa aaaatgtgac gcctgcggaa gtaagcaagg cgatggataa aattgatgaa
     4861 ttatcaaagc ttggggaaaa agaagccacg ctggaaacat taattaaagc aaaaggatac
     4921 agtgacgcgc tagtaagagc agacggaaag caagttcaaa ttaccgttaa gacagaaaaa
     4981 cactcaaaaa caaaagcaaa tcaaatcatt cagctagtta aaaaagaaat ggggccaaaa
     5041 gaagtagcgg tagagtttca gccaactaaa taaagggaat aaagggagtg taaaacagcc
     5101 ggaaattagg gttgtttaca cttctttttt tatgaaatga ctaaaatcga agcgagacgg
     5161 taaaaatttt aacatggctt tcttttttta cttcggttat aataggtttc ataatcttat
     5221 attagtacta ggtgacaagt gttttcacaa gtattgtcat ctgtaaagct atgtttccat
     5281 ttataaaacg ataacgctaa aaagttatta tagagtaagt ggaacttctt tttaatgttt
     5341 gccaaacgaa ttgaatggct gtagccattt atcgtattat taacattgta gagaattcta
     5401 ttttcatgag gtaggagtgt tcaatatgtt aaaaattcaa gagatccgtg agatcattaa
     5461 actagttgat caatcatcaa tcgaggagtt cacctatgag cacgaaggct ccaaaatcaa
     5521 gatgaagaaa aaagacgcaa ttgtttccaa acaagcgcag caagtagtgg tttcggcacc
     5581 tgaacaagca gcacctgcac cgcaggcagc agcggctcca gcgccagccc cagcagcaca
     5641 gtctgctcaa ccaaaagaag aacaagcggc cccagcggtt gatgagagct tacataaaat
     5701 tacatctccg atggtaggga cattctatgc gtcatcatcg ccagaatcag atgtatacgt
     5761 aactcctgga gataaagtac aaaaagattc ggttgtatgt atcgtagaag caatgaagtt
     5821 atttaatgaa atcgaagcag aagttaaagg tgaaatcgtt gacgtattag ttgaaaatgg
     5881 acaacttgta gaatacggtc aacctctttt cttagtaaag cctgaataag gagcggtaaa
     5941 tatgattaaa aagctattaa ttgcgaatcg aggagaaatt gcggttcgaa ttattcgagc
     6001 gtgtaaagag ttaggtgtag aatcagtagc tgttcattct caagctgatc gcgattcttt
     6061 gcatgtacaa ttagcagacg aagcgtattg tattggacca acgtcatcta aagacagcta
     6121 tttaaacttt acaaacatta tgagcgttgc gatgctgacg ggctgtgacg ccattcaccc
     6181 tggatacggc tttttagctg aaaacgctga ttttgcagag ctatgcagag agtgtaacgt
     6241 tacatttgta ggaccaagtc ctgaagccat taacaaaatg ggaacaaaag acgtagcgag
     6301 agaaacgatg cgtgaagcgg gtgtcccaat tgttcctggt tcaactggaa ttgtagagtc
     6361 agtggaagac ggtatgtcaa ttgctaatga tattggctat cctgttatta ttaaagcaac
     6421 ggcaggaggc ggaggaaaag gaatccgcgt tgcgaaaaat gaacaagaac ttatcaaagg
     6481 tattacaatt acacagcaag aagctgctac agctttcggt aaccctggtg tgtacattga
     6541 aaagttcatt gaggatttcc gtcacgttga gatccaagtg ttggctgatt ctcatgggaa
     6601 tactgtacat ttaggagagc gtgattgctc gattcaacgc cgtcttcaaa aattaattga
     6661 agaaacgcct tctccagcgt tagacgaaaa aacgcgtgaa ttaatgggcg acgctgctgt
     6721 taaagctgct caagccgtta attacacagg agccggaaca gtggaattca tttatgatta
     6781 ccgtgaaaac aaattttact tcatggaaat gaatacgcgt atccaagtag aacaccctgt
     6841 tacagagatg gtgacgggag ttgacttaat taaagaacaa atcaaagttg caaatggtga
     6901 aactttaccg tttacgcaag aagaagtgac atttaacgga tgggcaattg agtgccgaat
     6961 caacgcagaa aacccagaga aaaactttat gccatcacca ggtacgattc aaatgtactt
     7021 gccgccaggt ggctacggag tgcgcgtaga ctctgctgca tacccgggct atgcaatccc
     7081 accttactat gattcaatgg tggctaaatt gattgttcat gcgccaactc gtgaggaagc
     7141 tattgaacga atgaagcgcg cattagatga atttgttatc gacggcgttg cgaccactat
     7201 tccttttcac caaaaactat taaatcatga aaaatttgtt agtggtgaat tcaacacgaa
     7261 gtttcttgag ctatatgacg taatgaattc ttagtataat ataaactata ggaggtgctg
     7321 tacatgaatg aaaatcatgt attagaaatg gaagaacacc caaattctct tggcaaagta
     7381 gaaattgctc ctgaggttat tgaagtcatt gcgggtattg ctgcttctga agtagaaggc
     7441 gtttctgcaa tgagaggaaa ttttgcagct ggcgttgtgg agaaactagg aaagaaaaac
     7501 cacggtaaag gtgtaaaagt ggacttaaca gaaaacggga taaaagtaga cgtgttttgt
     7561 atgatgaagt ttggggtgtc tattccaaac gtagcgcaac aagtacaaga taacattcgt
     7621 caagccctta aaaatatgac agctattgat ctcgatgaag taaacattca tatcgtaggg
     7681 attcagtttg atacgcaaaa aactgatatt gaagaagttg aataaaacaa acgtttacct
     7741 aacggctgtt gctaaaatgg aataacgtat gattacttgt tccttttcaa cacaagctat
     7801 ggtaaagtga aaaagactgt ctcgtcataa agacggtctt tttcgtgttc tataaacttc
     7861 gtataagaac aatgaagtat cgtttcataa actatgctat tatctaggta tactagttga
     7921 agaagataaa taaaggagca aaaataatga aaagacatac agcacgccaa aaagcattac
     7981 aagcactatt tcagcatgat ttagggcaga ccgagccaat ggaggcaatc ggaaatgttg
     8041 tacaaaacga aaagtctgat caatttttag aaagtcttgt gctaggtgtg gttgaacatc
     8101 agcaagaaat tgatgaactt ttacgcaatc atttagaaaa atggacgtta gaccgcgtag
     8161 ctactgtaga ccgcgttatc ctgcgtattg ccgtatacga aatgaagtac gaagaagaaa
     8221 ttcctacgag cgttacgtta aatgaagcga ttgaattagc gaaaacgttt ggcgatgatc
     8281 aatcaagcaa gtttatcaat ggcgtattgt ctaaagtgtt aacaacttta tctaaataaa
     8341 ggttcatctt gccaagttaa gtgactaaaa tgcttctctc ctttatataa aggggagagg
     8401 gtgactgcaa aggaggcaaa atgatgggtg aagtgcgtta tctaaccgtt acggccctta
     8461 cacgatacat caagcgcaag tttgacgtag accctcacat gcaagatgta tggattaaag
     8521 gagaaatttc taactttaaa cgccatagtc gaggacatat gtattttacc ttaaaagatc
     8581 aaaatgctcg tatcgcagcc gttatgtttg ctgggcataa ccgtcagctt aattttcagc
     8641 ctgaagaagg aatgaatgta ctgattcgag ctgaaatttc ggtttatgaa ccaagcggaa
     8701 attatcaaat gtacgtaaaa gaaatgcagc ctgacggcgt tggaaactta tacttggcct
     8761 acgaacagct gaaaaaaaag ctggaaaaag aaggcttatt tgatcctgct agaaaacgaa
     8821 aactgccgaa gtatccaaca acaataggtg ttattacgtc tcctactgga gccgctgtac
     8881 gtgatattat tacaacatta aagcgcagat ataacgccaa cattattgtt atgcccgctc
     8941 ttgttcaagg agtcaatgcg gccccgtcta tcatcaaggc aattgaagaa gcaaaccgtc
     9001 gtaaagaagc agacgtatta attgttgggc gcggtggtgg gtcaattgaa gagctttggg
     9061 cttttaacga agaaagcgtt gctcgtgcaa ttttcacttc tactattcct gttatttcag
     9121 cggttggaca tgaaaccgat tttacgattg cagactttgt agcagatctg cgcgccccta
     9181 ctccaacggg tgctgcagaa ttggctgtgc ctcatatcag tgaaattaca gaaagattga
     9241 ctcagcgaaa tatccgtctt cttcgttcga tgaaagagat gcttcagtct agtagccgca
     9301 ggcttgaacg atctcagaaa tcatatgctt ttcgttatcc tcaaaagttg gtcgagcaaa
     9361 aagagcagca gttagaccag ctgatggagc gtttttatcg tgaaggtaga agatacattg
     9421 agcataaacg gacgaactac gagcagctaa cagccgcttt gttacgaaat catcctgagc
     9481 atcagttaat gaaagcagca gagcgtcaac agcagctgac gaaaatgctg acaaaagaga
     9541 tgcagcagct gctaaagcaa aaacagcttt tatttgccac ggcaacgtca aaattacata
     9601 cgcttagtcc attaaaaaca atggaaagag gctacagctt agtatacgat aaagaaaaag
     9661 agttaattaa atcaaccaaa caagtatcca aaggcgatgt ggtaaacgtt cgtttgaccg
     9721 atggacaatt gcagtgtgaa gtttcgaaaa tagaggagcg atgaaaaatg gcgacaaata
     9781 aagagtatac gtttgaagag gcgatggagc agttagaaac catcgtaaac aagctagaag
     9841 aaggcgacgt gcctttagaa gaagcaattc aacaattcca agaaggaatg actctttcaa
     9901 aattctgtca cgatcgtctt cagcatattg aaaagcaaat ggaaactatt ttacgtgaag
     9961 acggaacgct tgagccattc tcggtacagg aggaagagtg atggtgaatg aaatgaattt
    10021 aaaagagtat atttctttta caaaagatcg agtagaaaca cgcttgcctg aagtggtaaa
    10081 agcattacat gctccggtta acttaaagga atccatgctt tactcgctta cggcaggagg
    10141 aaagcgactt cgcccagtgc tgttgtttgc aacgctacat gcgtttggaa aagatgagag
    10201 catgggatta gaaacagcat gtgcagtgga aatgattcat acatattctc tcattcacga
    10261 tgatttacct agcatggatg atgacgactt aagaagaggt aaaccgacga atcacaaggt
    10321 gtacggcgaa gcaacggcta tattagctgg agatgctctt ttaacaaata gctttcagct
    10381 catttctgaa gcggcacatc ctgagattac atcacatatg aagcttcagc tcattacaga
    10441 actggtaaaa gcaagcggaa cagaaggtat gatcagcgga caggttgcgg atatggaagg
    10501 cgaaaaaaag cagctcacgc tagatgagct tgaatatatt caccttcaca aaacggggaa
    10561 gctgctagag ttttgtgtaa aagcaggagc tattcttgca aaagctacgc ctctacagca
    10621 aaaattatta gaagaattca gtaagcatgt agggttagca tttcaaattc aagatgatat
    10681 cttggatgtg gaagggtctg aagaaaaatt aggaaagcca attggcagtg atacagaaaa
    10741 tgaaaaaacg acatatcctt ctttgttagg tatggaagcg gccaaagaaa agttacagta
    10801 tcatgttgaa caagcacttc tctcgttacg tcaagctcaa attaagcacg ggttactaga
    10861 agaaatttgt ttatatatag caaaacgtga tagttaatga cgatttctgt caggtttttt
    10921 gagtgataca gtaaaataag attgagtccc aataggggct atgctataat gattttacta
    10981 ctgtataaaa gcgtagtgca taggtttgaa agacatatac aatatcttgg tggccgttat
    11041 cacatttgtg ttagcggcta ttttttcact attttccttt gaatatcact ggtttactga
    11101 tagaatatca aaggtattgt aagtaataag gaaatactaa aaattgacta tacgtataaa
    11161 acaatagaca atgtattaag gtaactttat aacaagtacg aaagtgagtg atccaccttg
    11221 gatcttacaa cgataaaaaa tcctgagttt ttaaagaaaa tgtcagtaac acaattagaa
    11281 gaactaagtg aagagattcg tcgtttttta attacaaagc tttctgcaac tggtggtcat
    11341 atagggccaa atttgggggt tgttgagtta acgcttgcac tccataaagt gttcgacagc
    11401 ccaaaagata aatttttatg ggacgtcggg catcagtcgt atgtccataa aattttaaca
    11461 ggacgagcgg gagagtttga tacaatccgt caatataaag gattatgcgg ttttccaaag
    11521 cgagatgaaa gtgagcatga tgtatgggaa acgggacata gttctacatc actttcagcc
    11581 gcaatgggaa tggctgcagc aagagatttg caaaaaacaa aagctcacat tgttcctatc
    11641 attggtgacg gagctttaac aggtggtatg gctcttgaag cgcttaacca catcgggcac
    11701 gagcaaacgg atatgaccgt tattttaaat gacaatgaaa tgtctatcgc tcctaacgtg
    11761 ggggctgtac acagcattct agggcgtttg cgcacggcag gcaaatacaa ctgggtaaaa
    11821 gatgagcttg aagtcttgct gaaaaaagtg cctgcagtag gcggtaagct tgcggcaacg
    11881 gcagaacggg taaaagatgg cctaaagtac atggttgtgt caggcatgtt ctttgaagat
    11941 cttggcttta cgtatttagg gccggttgac ggccatagct atgatgattt attggaaacg
    12001 ttacaatatg caaagaaaac aaaaggaccg gtactgattc acgtgattac gaaaaaaggg
    12061 aaagggtact tgccggcgga aagcgataaa agcggagcgt ggcatggtac aggcccttac
    12121 aaaattgagt ccggtgactt tattaaagac aaaaatgttc cgattgcttg gagtaaatta
    12181 gtaagcgata cggtattgaa aatggctagg gaagatgagc gtatcgtagc cgtaacgcca
    12241 gcaatgcctg taggctcaaa acttgaagcg tttcaaaaag agtttccgca tcgcatgttt
    12301 gatgttggga ttgcagagca gcatgcaaca acaatggcag cgggtcttgc aactcaaaat
    12361 atgaagccct ttttagctat ttattctacg tttttacagc gcgcatacga tcaagtagtt
    12421 catgatattt gccgtcagaa gctaaatgta tttattggca ttgatcgcgc tggactagta
    12481 ggtgctgatg gtgaaacgca ccaaggcgta tttgatattg cgttcttacg tcatttgcct
    12541 aaccttgtta ttatgatgcc aaaagacgag aatgaaggtc agcacatggt tcatactgct
    12601 ttgacttatg aagaaggtcc gattgccatg cgctatgcga gaggaaacgg attaggtgtt
    12661 gaactcgatt cagaactgaa aaacattccg atcggtacat gggacgtatt aaaagaaggt
    12721 tcagatacaa ccattttaac gtttggtaca acgatttcaa tggcgatgga tgcagcagca
    12781 gaacttgaga agcaaggaat cagcgtaaaa gtggtcaatg ctcgttttat taaaccgctg
    12841 gatgaaaaaa tgcttcatga gattttccaa actagtaagc ctgtgattac ggttgaagaa
    12901 gcggtacttc aaggcggttt tggaagcgcg gtgttagagt ttgcatcaga gcatggctat
    12961 tatgatacgc gcgttgaacg tatgggtatt cctgatcgct ttatcgagca cggcagcgta
    13021 acaaaacttt tagaagaaat tggcttaacc aaagaagaga ttataaatcg agttaaaaaa
    13081 ctcgtaacac caacacaaaa gaggcttgaa gttaagtgac aaaaaaagaa cgagtagatg
    13141 tattattagt agaacgaggt ttgattgaaa caagagaaaa agcaaagcgt acagtgatgg
    13201 caggacttgt ttatgcgaat gaagtccgtt tggataagcc gggagagaaa attgaacggg
    13261 atacgccgct gacaattaaa ggtgcagtga tgccttatgt cagcagaggc ggctttaagc
    13321 ttgaaaaagc gattaaagaa tttaatgtcc atgtagcgga taaaatcatg attgatattg
    13381 gttcttctac tggaggcttt actgattgtg cgcttcaaaa tggagcgaag atgtcctatg
    13441 cgctagacgt aggctataat cagctagctt ggaagcttcg tcaagatgag cgagtagaag
    13501 taatggaacg aacaaatttc cgttatgtga caccggctga tttatcaaga ggcttgcctg
    13561 aattcgcttc tattgatgta tcatttattt ccttaagact cattcttcct gtgttaaaaa
    13621 cacttcttgt tccacacagc gatgttgttg cgctcgttaa gccacaattt gaggctggaa
    13681 gagagcaagt tgggaaaaaa ggaatcgtgc gtgattcaaa agtgcatgaa gaagtcctcc
    13741 aaggcatggt agatttctcg cttcgtcaag gatacgatgt atataacatg tcgtattcac
    13801 cgataacagg aggagatgga aatatcgaat ttcttctcca cctgcgctgg aaaggcgagc
    13861 gtgaacttgg tgaaaatcaa gctccgctta ctgtgcatga agtagtcgaa gaagcacata
    13921 agacgttaaa agagaaaaag taataatggc caatgttaag caaagactta gcattggcga
    13981 tttgattatg actctttata caaaaggtgc ataatcaagt tgaacacatt atgatactta
    14041 attagtgaaa gacttataaa caacaaaaca aaacgaagat tacatattaa tgtgaggtgc
    14101 caacatgaat aaagggcaaa gacatattaa aattcgtgat attatcacga ataatgatat
    14161 tgaaacacaa gatgaattag tagatatttt aaaaaaccaa ggttttaatg taacacaggc
    14221 aacaatctct cgtgatatta aagaactgca cttggtcaaa gtgcctttga tggacgggcg
    14281 atacaaatac agcttgcctg cagatcagcg ttttaatccc ttacaaaagt taaagcgctc
    14341 tcttatggac gcatttgtaa aaattgattc agccgggcat atgctggtga tgaaaacatt
    14401 gccgggaaac gcaaatgcga ttggcgcatt aattgatcat ttggactggg atgaaatatt
    14461 aggaacaatt tgtggagacg atacatgttt gattatttgc cgtactcctg aagatacgca
    14521 aattatatca gaccgattct tagaaatgtt ataaaggtga gtgaagcagg ttgttagctg
    14581 aattatccat taaaaacttt gcgattattg atgaactttc tgtttcattt gaaaaaggct
    14641 taacggtatt aacaggcgaa acaggagcgg gaaaatcgat tattattgat gccatttcat
    14701 tgttagtagg tggaagaggc tcttcggagt ttgtccgcca tggaacagac agagccgaaa
    14761 ttgaagggct tttcttattt gatgaagaac agcatccgag tcacgaaaaa gccaaacaag
    14821 tcggtttgga agtggaagat ggaatgattg tgcttcgccg agatatcact acaaatggga
    14881 aaagtatttg ccgtatcaat gggaagctcg taacgttagc tatcctacgt gaagtcggac
    14941 agacgttaat tgatatacat ggacagcacg agcaccaaga tttaatgaat caagatcgtc
    15001 acttaactct tcttgatcaa tatggaggag aaaaagtaga agaggctttg acggagtatc
    15061 gagaggtatt ttctagatat acatcattaa aaaagcagtt ggatcaatta actgaaaatg
    15121 agcagcagat ggcacatcgc ctcgatctta ttcaatttca attagatgaa atcaaagcgg
    15181 caaatttgca actcaatgaa gacgaggaac taaatgaaga gcgtttgaag atttccaact
    15241 ttgaaaagat ctatacgtcg ctaaacgatg cgtacaatgc gctgcacggt gaacatcaag
    15301 gtttggattg ggtaggcgta gcaatgaatc atacggagga tatttcgtca ctggaaaaaa
    15361 actatgccga aatttcggag attatttcat cgagcttcta tcagttagaa gacgcatctt
    15421 ataaaattcg tcagcagctg gatttattag aatttgatcc gaaacgctta gactttattg
    15481 aagcgcgttt aaatgaaatt aatcatttaa agcgtaaata cggtcaaagt gtagatgaaa
    15541 ttctagaata tgcagcgcaa attgaagatg aaattgatcg tattgaaaat agagatacgc
    15601 acgtgagcaa aatcaaagaa cagttaaaca gcgtagcaca ggatttatta gtagaagcta
    15661 acaacgtttc agctattcga aaaaaacttg ctcaggagtt aacggacagc atccatcatg
    15721 agcttcaaga actgtatatg gctaaaaccg tatttcaaat taaattttct gttgtaaatg
    15781 caggtaaaaa tgacgttgaa gtaaatggag aaagaataaa attcaccaaa gacggcattg
    15841 acaacgtagc gttttatatt tctaccaacc ctggtgaacc gttaaagcct cttgcaaaag
    15901 tagcatcagg aggagaactg tcaagaatta tgctggcgtt aaaaagcatc ttctctaaac
    15961 atcaaggtgt gacgtccatt atctttgatg aagttgatac aggggtaagc ggaagagtag
    16021 ctcaatcgat cggtgaaaaa atacatgcca tttccgttga ttcacaggtt ctttgcatat
    16081 ctcatttgcc gcaagtagca gctatggcag atactcatct ctttattgct aaagagataa
    16141 aaggtgatcg tacaaccacg tctgttcttc cattaactct tgatgaaaaa gtaaaagaga
    16201 ttggtcgaat gattgcagga gctgaaatta caagcttaac gaaagaacat gccaaagagc
    16261 ttttagattt agcggataag atgaagcaga ccatttaaaa aaaacacctt ttaacacgta
    16321 acagtatgtg ttaaaggtgt ttttttatac aaaatggagg aactgaaaat gtttccttgc
    16381 acttcttttc atttttctct gaacttctgt tataaatgcg ctctaagaag gctaaattaa
    16441 atgtgtagcc atttaggcga ggaagcgagg agagtgaaaa catgcaaaat ctatacagac
    16501 atataattgg tgcgattctc cttgtttcgt tcatttttgt aggatttatt ccagttgtgc
    16561 aacaatatat acacattcca aaacaaatcg tcttatttga acagcaaaaa gaaaaaatta
    16621 atacgacatt accccttagc gtagaagctt catcacctgt ttacgatgta acaagtaaca
    16681 aggcgaagct gaccgtagca ggcaaacagg taggcaaaga agagttgatg cttcatttgg
    16741 ccggtattcc tgtaaagcgt gtagacgtgc aggtattatc tgattttaaa gtcattccag
    16801 gtggacaatc aatcggtgtg aaattaaatt caaaaggtgt tcttgttgta ggctatcatc
    16861 aggtagatac agcaaaaggt aaaaaatctc ctggagaaat tgccggtatt caagttggag
    16921 atatgattac gaagattaat ggtaaaacca ttgaaaaaat gagtgatatt acaccgttta
    16981 ttcagcaggc aggaaaaacg ggtgaaccat taaatctgca tattttaaga gaaaaaaagc
    17041 agtttgacac taagctatat ccgttaaaag ataagcaaga ttatgcttac agaatcggtt
    17101 tatacattcg tgattcagct gcaggaatcg gtacaatgac tttttatgat ccaaaatcta
    17161 aaaaatacgg cgctttaggc catgttattt cagatatgga tacaaaaaag ccaatcgtag
    17221 tagaagatgg ccaaattgtc cgttcgaccg tcacatcgat cgagaaaggt tctaacggcg
    17281 ttccaggcga aaagttagca aggttttctg aagatagaca aatcattgga aatattacac
    17341 gaaatagtcc ttttggtatt tttggaaaat tgtcttcaac aatggaaaac ggaataatgg
    17401 ataaagcaat gccaattgct ctatctcatc aagtaaaaga aggacctgct aaaattctaa
    17461 cggtagtaga tgatgatcaa gtggaagaat ttgatattga aattatgagt actatacctc
    17521 aaaagtttcc ggctactaaa ggaatggtta ttaaaattac agatcctaaa ttgctaaaga
    17581 aaacaggtgg aattgttcaa ggaatgagcg ggagtccgat aattcaaaac ggtaaagtcg
    17641 ttggagcggt tacccatgtt tttgtaaatg atcctacctc aggttacggt gtccacattg
    17701 aatggatgct taacgaagca ggaatcgata tttataaaaa taatcgaaaa aaagcgagct
    17761 aatgttgtca ttagttcgct ttttttgata aaaattattg tcgtaaatgt acgagaaaaa
    17821 cgtcgaaaaa caaagaaaat aagagaaaat cgaataaatt ccatttaaaa gacttttttc
    17881 taaaaaaata aaggaaataa tgttgcattg tcgaatttgt cctttagaat aaagaataga
    17941 gacacgtagg aaacgacgta taacataaag gactgaggag gaagctgcat tgaaaaaaat
    18001 taaagtatgc ttggttgatg ataatcggga actaattggt ttgcttgaag attatatttc
    18061 agagcaagaa gacatggaag taatcggagt agcttacaat ggacaagagt gtttatccat
    18121 tttaaaagat aaagatccgg atgttcttgt attagacatt attatgccgc atctagatgg
    18181 attagcagtt ttaggtcagt tgaaagaaat gaaaaaagaa aattatccaa atgtcattat
    18241 gctaacagca tttgggcaag aagacgtaac gaaaaaagcg gtcgatttag gagctgctta
    18301 ttttattcta aagccgtttg atatggaaaa cttagtgaat catattcgtc aagttagcgg
    18361 acaaacatct tcatttatgc aacgttcatc ttcttctatg cgttcacatc gcgacagcaa
    18421 accagcaaat ttagatgcca gcattacgag catcattcac gaaattggtg tgcctgctca
    18481 tattaaaggc tatttatatt tgagagaagc catttcaatg gtatataagg atattgagct
    18541 gcttgggtcg attacaaaag tactgtatcc tgatattgca aaaaaatata atacaacagc
    18601 aagccgcgtt gagcgcgcca ttcgtcatgc tattgaagta gcatggagcc gaggaaacat
    18661 tgattccatt tcttcattat tcggatatac tgtcagcatg tcaaaagcga agccgacaaa
    18721 tagtgaattt atcgccatgg tggcggataa attacgcctt gaacataaag cgagttgaaa
    18781 gggataggag cgcagtttga agcgctattg cccgtaacct ctgcttaccg actaatcact
    18841 ttttaagccg ataaatacct tagcgtatat tgaataataa cattaacctc ttatttaccg
    18901 atagaagacg gtagataggg gggtttttgc gttgtctgaa ttacatttgc agttagataa
    18961 ctttatgctt cattgcgata gtaaaggttt aagccgtaaa acgctaaaaa gctatgagca
    19021 aacgctaaga ttatttattt cgttcttaga aaataagcac aaggtaaccg aagccgaaaa
    19081 ggtgaggacg gtgcatatac gggcttatat actttaccta cgtaaaagag gtaaatacac
    19141 ggttgtagct gatgaactaa gcgctaactt aaaccatcca acgcaccgta cagattttag
    19201 caagcctatc agcgatacta ctattgcgaa ttacttacgt aacattaagg tgtttttcaa
    19261 cttattatac gatgaaaacg aaataacaga aaatcctgct aaaaaggtag ctaacattaa
    19321 gcccgcacgt aagcaaaagg cgctattaac ggaagatgaa atagtaaaag tactaagggc
    19381 gtttgatata actacatttc acggttatag atcatggcta caggtacggc tattactgga
    19441 tacgggcatt aggtcgggtg agtgctgctc tttacaacca gaaaacgttg atataaaaaa
    19501 tagggcgtta ttaatcgaaa atccaaagaa caacaagcag agatacgtgt atttttcggc
    19561 taaaatggca aacgatttac gccgttggtt gctgtatagg gataggtttt cagaaagtga
    19621 gtacctgttt cctacgacaa gaggcactat gcttgatact aataatttcg agaagatgtt
    19681 gaagcaggca ggtaaacgtg taggcgtggc aatacatgcg caccagttac gaaatacttt
    19741 tgctaaatat tatctgctaa acggcggaga ttttgttaca ttatcacgtt tattagggca
    19801 ttcgagcgtc gaagtaacac agaaagcgta tttagatttt gcagaaaatg aagtagcacg
    19861 taaatatcaa cggcattcgc cattaaacaa aatgaattta taaaaaatac aaaaaaaaaa
    19921 tagagcgcct gcaaacgcag acacccgtat tacttccgac aaggtaatat tatcacgctt
    19981 taaaaaaata gacaagcgta taaggtattt gtgcgtgtat gaaaccgaac gtatattctc
    20041 gtttgtaggc gttttaatgg agggaaacgc tatgtatcaa gaattagcga aacagcaccg
    20101 tacatttgat aacgtagaac atctgaatta tgcagttaga aagcatttat atcataataa
    20161 gcaccagtta agtcaaacgg ctatagatgt gtttaagcta ttagcacgcc atgcagtaaa
    20221 atacgttggt gtcgcttatt tgaagattga aacaatcgca aaagctattg ataaacatcg
    20281 ttctacggtt atgcgtgcgc ttaaagtatt agctgaatta aatattatcg aaaagctaac
    20341 gcaatacaga cctaaaacag gtggaaatgg agctaatatc tacgtcatcc aacgttataa
    20401 accaatgcag ggcgaagtta aaaatagcgc tgaaaatact aatgctactc cgagcgtgca
    20461 actccgtaat gaagctgaaa acacagtagt agcaagcgtt gacagcccta aaacggtaac
    20521 tgaaacagag attcctgaaa gcattaataa agttcttaaa agaatacgta gtataacgcc
    20581 gtacagtgaa tttaaaaact gggttaatgc ttatgttaag gataacaagc taactaataa
    20641 gctttacgga atttataagg cgcaaacaca ttacataaaa ggcgtatatg gcgctgaatt
    20701 actgttacac gtaggcatac aggcaattaa aacgacattt acagctacta aacgtaaaaa
    20761 cattaaaagc ttaacaggct actttaacgg cgttttagat aagttactgg atagacttta
    20821 ctactcaact attggacaac cttgtataat ttaacttata taccatttta ttagttatat
    20881 gagggggaat tcttgtg
//
