LOCUS       NZ_CP063142            28883 bp    DNA     circular CON 30-MAR-2024
DEFINITION  Priestia filamentosa strain GN1 chromosome.
ACCESSION   NZ_CP063142
VERSION     NZ_CP063142.1
KEYWORDS    RefSeq.
SOURCE      Priestia filamentosa
  ORGANISM  Priestia filamentosa
            Bacteria; Bacillota; Bacilli; Bacillales; Bacillaceae; Priestia.
REFERENCE   1  (bases 1 to 5133640)
  AUTHORS   Buch,A., Patel,D. and Chandnani,M.
  TITLE     HCA producing B. filamentosus GN1
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 5133640)
  AUTHORS   Buch,A., Patel,D. and Chandnani,M.
  TITLE     Direct Submission
  JOURNAL   Submitted (17-MAY-2020) Department of Biological Sciences, P D Patel
            Institute of Applied Sciences, Charotar University of Science and
            Technology, Changa, Anand, Gujarat 388421, India
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: SPAdes v. v-3.13.0
            Assembly Name                     :: CHAR_BFil_1.1
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 100.0x
            Sequencing Technology             :: Illumina Nextseq500
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_022811745.1-RS_2024_03_29
            Annotation Date                   :: 03/29/2024 08:14:31
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 5,159
            CDSs (total)                      :: 5,093
            Genes (coding)                    :: 5,023
            CDSs (with protein)               :: 5,023
            Genes (RNA)                       :: 66
            rRNAs                             :: 2, 1 (5S, 16S)
            complete rRNAs                    :: 2, 1 (5S, 16S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 21 of 70
            Pseudo Genes (incomplete)         :: 52 of 70
            Pseudo Genes (internal stop)      :: 15 of 70
            Pseudo Genes (multiple problems)  :: 15 of 70
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 10:46:23
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 4288133
            Orig. end                         :: 4317016
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP063142.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            Bacteria and source DNA available from Dr Aditi Buch, Department of
            Biological Sciences, P D Patel Institute of Applied Sciences,
            CHARUSAT.
FEATURES             Location/Qualifiers
     region          1..28883
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="lanthipeptide-class-ii"
                     /region_number="14"
                     /rules="cds(LANC_like and DUF4135)"
                     /tool="antismash"
     cand_cluster    1..28883
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="cds(LANC_like and DUF4135)"
                     /kind="single"
                     /product="lanthipeptide-class-ii"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..28883
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:18883](-)"
                     /cutoff="20000"
                     /detection_rule="cds(LANC_like and DUF4135)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-ii"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..18883)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="cds(LANC_like and DUF4135)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-ii"
                     /protocluster_number="1"
     misc_feature    complement(315..331)
                     /note="TFBS match to GnfM, Regulator of nitrogen-fixation
                     genes, confidence: medium, score: 22.04"
                     /tool="antismash"
     gene            complement(485..919)
                     /locus_tag="HPB58_RS21400"
                     /old_locus_tag="HPB58_21345"
     CDS             complement(485..919)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="HPB58_RS21400"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="HPB58_21345"
                     /product="hypothetical protein"
                     /protein_id="WP_243514155.1"
                     /transl_table=11
                     /translation="MKISEVLTGIEALYEQMTEQCFSHIAKHKEEIKIDALALVELEKL
                     VSHLQHTELYNLSLIKTIQTLINHESFLYKLSILREPELENIAEKADFVGNERQDIEKI
                     LRISYIKKRSQYIEEALDDIKKLKASLEELLYAKKVQKEG"
     gene            complement(1008..1532)
                     /locus_tag="HPB58_RS21405"
                     /old_locus_tag="HPB58_21350"
     CDS             complement(1008..1532)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF019416.4"
                     /locus_tag="HPB58_RS21405"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HPB58_21350"
                     /product="DUF1643 domain-containing protein"
                     /protein_id="WP_243514156.1"
                     /transl_table=11
                     /translation="MKREAIFDETGTYRYSLKRKWGNDRERKVAFITLYPDNADEVRED
                     YVTSKCITFAKKWGFNAVECLNLFSYRAQKADDLSDLDKEDAIGAETDRYLYYGTRNAD
                     LVIAAWGKNVFHDRENDIKQLFEGMDLACFSGQENHPSQLQFISYDTRLMPFELEAEEP
                     YLFSAFPSLYR"
     gene            1764..2408
                     /locus_tag="HPB58_RS21410"
                     /old_locus_tag="HPB58_21355"
     CDS             1764..2408
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019393708.1"
                     /locus_tag="HPB58_RS21410"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HPB58_21355"
                     /product="hemolysin III family protein"
                     /protein_id="WP_243514157.1"
                     /transl_table=11
                     /translation="MSETHTFSRGEEIANAITHGIGTILSIVGLTLLIVFSVQFGDVWH
                     VVSFTVYGTTMLLLYTSSTLVHSFPHGRVKDLFEIFDHSSIYLFIAGTYTPFLFVIIQG
                     TVGWTLFGVVWGLAVAGIVFKIFFVKRFVLVSTLLYIAMGWLIVLAWDPLASSLAGPGL
                     NLLVVGGVLYTIGSIFYVWRGFPYHHAIWHIFVLGGTITHYLAILLYVLPH"
     gene            2696..2992
                     /locus_tag="HPB58_RS21415"
                     /old_locus_tag="HPB58_21360"
     CDS             2696..2992
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="HPB58_RS21415"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="HPB58_21360"
                     /product="hypothetical protein"
                     /protein_id="WP_040057094.1"
                     /transl_table=11
                     /translation="MIQKKGKLIVIIVLFFFFIYLLVFSPFNAIQTFYPESILNEHTLS
                     EKFEKMQVQKVEKKGRYTYIVKTNKQDYVVIKEYSSIIHYNWRVYPFTKEENF"
     gene            complement(3000..3950)
                     /locus_tag="HPB58_RS21420"
                     /old_locus_tag="HPB58_21365"
     CDS             complement(3000..3950)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:TIGR03943.1"
                     /locus_tag="HPB58_RS21420"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HPB58_21365"
                     /product="TIGR03943 family protein"
                     /protein_id="WP_243514158.1"
                     /transl_table=11
                     /translation="MKNDEEGFHYYIRGLLLIGFALFIFKLLLTGYISSFVAPKMLGFV
                     TFASFTFFVLGAVGIWRSGSDKKQKSCSCHHSRKAPLWVYCLFFLPIATGFLFPDHALT
                     SDVAKNRGVKFGANVTERPSVEQREELTSDESLEQYYDEVLNREVEEAQTEAGEIPLEH
                     KAGFVPQKPPEGYYEELKERMLQKDVITITEKEYIPMMNILEEHVEDFVGKKVEVKGFI
                     YREDNFKKDEFVIARFGLSCCVADASVYGTLANVKESKEFADDDWVEATGTIEKKEYDG
                     FILPSLKLQTIKKVEAPTNPYVYEMYKGNKLMTPK"
     gene            complement(3961..4938)
                     /locus_tag="HPB58_RS21425"
                     /old_locus_tag="HPB58_21370"
     CDS             complement(3961..4938)
                     /GO_component="GO:0005886 - plasma membrane [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019393711.1"
                     /locus_tag="HPB58_RS21425"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HPB58_21370"
                     /product="permease"
                     /protein_id="WP_243514159.1"
                     /transl_table=11
                     /translation="MALSRLSKEVLGVLLILFFGYAFFFLDVKDFDMNFPKAFLNVNTI
                     FLSILLEAIPFILLGVFASAIIQVFVKEEWLMKWIPKNPYKALASGVVVSALLPVCECA
                     IIPVVRRLVKKGMPIHVGVVLLVGAPILNPIVFLSTFYAFPGNKEIVYGRMGLTVILCF
                     IIGIVMYKLLKNNPQLKDEAAVEEPHQHGNRLSQTLFHAIDEFFDMGKYLIAGAFIASL
                     FQTFLDRGELMSIGGNGFIAPVVMMVFGYVLSLCSEADAFVASSFVDTFSASSLLAFLI
                     YGPMLDLKNTVMYLAFFKKRFVLMFIAVVTISVYTITVLYNFIM"
     gene            5182..6342
                     /locus_tag="HPB58_RS21430"
                     /old_locus_tag="HPB58_21375"
     CDS             5182..6342
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Pyr_redox_2"
                     /gene_functions="other (smcogs) SMCOG1092: hypothetical
                     protein"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019393712.1"
                     /locus_tag="HPB58_RS21430"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HPB58_21375"
                     /product="FAD/NAD(P)-binding protein"
                     /protein_id="WP_243514160.1"
                     /sec_met_domain="Pyr_redox_2 (E-value: 1.7e-07, bitscore:
                     29.0, seeds: 64, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLDWIVIGGGIQGTTMAHFLVQIRKVPIEKLAIVDPHKAPLENWH
                     SCTEKIDMSFLRSPSVHHLDVEPFSLQNFVSKNRSLTKQDFYGRYKRPSLYAFSEHCKH
                     LIRDSNLLQAWHKGRVVSLSRIKKHWMVITEEGKKLESLNIVLAIGVSEQTYWPEWAKL
                     LKNKDAQSVGHIFDSSFSLNKSQEITIIGGGISAAHLAIKLSKQGRSVHLITRHPFRIV
                     DFDSDPAWLGPKNQLMFREETSYQKRRAFITDARHRGSMPRDIYIKLIEQTRKNNLTIS
                     KDEIQEANIKDKKILLYGKIAQYETETIVLATGFSSSLPGKEWLTPLINTENLQCSDCG
                     YPIVSSSLQWSHNLYVVGALAELEIGPISRNISGARQAAEQIVQSL"
     gene            6445..7611
                     /locus_tag="HPB58_RS21435"
                     /old_locus_tag="HPB58_21380"
     CDS             6445..7611
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1178: cobalamin synthesis protein/P47K family protein"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019393713.1"
                     /locus_tag="HPB58_RS21435"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HPB58_21380"
                     /product="GTP-binding protein"
                     /protein_id="WP_243514161.1"
                     /transl_table=11
                     /translation="MKKIGVTVLSGYLGAGKTTLLHHILHNESSLKLGVIVNDMSSLNI
                     DGSLVKKEYFSHTKETLVEMQNGCICCTLREDLLYEVENLTKIQDLDYIIIESSGISEP
                     LPVAQTFSYEDEETGIDLTVKTFLDTLVTVVDGLNFMKDYCSNEDLSDRNQGSDSTDDR
                     SISELLIEQIEYANVLILNKTDLLSAEKKDELKALLRKLNGEAKIIEAVQCSVSLEVII
                     NTRSFDFDKMSLSPGWVKELNNEHTPETEEYGITSFIYEKRRPFHAQRLMNFFETFPNE
                     ISRSKGFFWVATRNDVACLLSQAGGSMTISEAGKWVNTLSDEDKEDIELSSRFHPTYGD
                     RLTELVFIGIKMNKNKIINALDACLLTNEEMKKDWSTFNDPLPSFLIQ"
     gene            7626..8588
                     /locus_tag="HPB58_RS21440"
                     /old_locus_tag="HPB58_21385"
     CDS             7626..8588
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1252: cation ABC
                     transporter, periplasmic"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009329427.1"
                     /locus_tag="HPB58_RS21440"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HPB58_21385"
                     /product="metal ABC transporter substrate-binding protein"
                     /protein_id="WP_243514167.1"
                     /transl_table=11
                     /translation="MKKLMMLCSVMLLFALFLAGCGNEDSSSSEKKSDGKLTIYTTIYP
                     IEDFTKKIGGDNVTVKSVIPNGVDAHSFEPTTKDMLKIAKADAFIYSGAGAEGFADAAN
                     KTLKDEDVKMIKAAEGAELVAGHDDHDHEHGEEHGDEHEHGDLDPHFWLDPQRSIVMAE
                     NIKNALSELEPSKKDEFEKNFNQVKTDLEELDKKYEEAIKNAPSKEILVSHAAYGYWED
                     RYGIEQISVSGLSPTQEPSQKELKEIVETAKEHNIKYVIFDANVTNKIATLVRKEIGAE
                     SLTLNNMETLRDQDRENGEDYFSLMNKNLEALKKALNSK"
     gene            complement(8620..9987)
                     /locus_tag="HPB58_RS21445"
                     /old_locus_tag="HPB58_21390"
     CDS             complement(8620..9987)
                     /GO_function="GO:0008236 - serine-type peptidase activity
                     [Evidence IEA]"
                     /GO_process="GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_S8"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1075: alkaline serine protease, subtilase family"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF012311.4"
                     /locus_tag="HPB58_RS21445"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HPB58_21390"
                     /product="S8 family serine peptidase"
                     /protein_id="WP_243514170.1"
                     /sec_met_domain="Peptidase_S8 (E-value: 5e-45, bitscore:
                     152.3, seeds: 43, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKKKNLISLLFCSILFLCINAEVQADGTSYYSVLLSKPEYTEEFL
                     REAQQHNMNITYVVKEIGLIQIKASEAEVQILDGNKMVQTYNYSLKAAPSEFSTKQSDV
                     VGAPSSLWDRQWDMKEITNNGKSYTISEGSKKVVVGIIDSGIDADHPSLKKNIIKGSKN
                     LVPQGGFRETEQSEKGIINNIEDMTGHGTHVAGQVAANGVVKGVAPQTSLKSYRVFGTS
                     SAESIWIIKGIIEAAKDDVDVINLSLGEYLTSEHMNEEGGSSKSQLAEILAYEKAVMFA
                     EGKGSVVVASVGNDSVNFNNKNEVSSFMKSHFQLNHAKVKGHLLDVPAHIKGVVAVTST
                     GPAKELSVFSNRGRYVDLSAPGGDIKLLQTYGVEKWRKMELFMKEQVLSTSPKGGYIYM
                     AGTSSAAPKVSGTLALIIDQYNLKDNPKKAKQKLLQKSKRSAETNIKALNTYKAIK"
     gene            complement(10001..12901)
                     /locus_tag="HPB58_RS21450"
                     /old_locus_tag="HPB58_21395"
     CDS             complement(10001..12901)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-ii: DUF4135"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-ii: LANC_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1070: lanthionine synthetase C family protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:TIGR03897.1"
                     /locus_tag="HPB58_RS21450"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HPB58_21395"
                     /product="type 2 lanthipeptide synthetase LanM family
                     protein"
                     /protein_id="WP_276517203.1"
                     /sec_met_domain="DUF4135 (E-value: 2.5e-83, bitscore:
                     278.6, seeds: 79, tool: rule-based-clusters)"
                     /sec_met_domain="LANC_like (E-value: 4.9e-58, bitscore:
                     194.8, seeds: 47, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKLFYKSKFYPPHFNTVFLGNQKFQFTPFTEEDEFPSFYTHFTER
                     FSEKLVKELGRLNQSFFDLKSLLYSLIIQYKKMLYKLARKTVIYEFHEMFDEFHREEDF
                     FYRRFNDTFSNYSAVENILKKYPVLSEMMDRTSNQFIQYSLSIIKAYIAHYEEIAETFH
                     QQLGRLLSIKVDAGDSHCEGKSVAILTCECGKIVYKPRSLEGDQLYQKMIKYFNHQYDT
                     KLKTPIMISKNNYGFQEYIESTSCQTLDEVSNYYYELGMHLAFIYAFQGSDFHYENIIC
                     NGLHPVLIDLETLFQSTLYFTEESKKDSVLKVSSSINRTVYKSTFFTHTSYPEENYVVD
                     ISGLTNIELHTFNKEIVVNNKTDKIAVEFQETKFGRGTNLPIYKDNGIEIFGYEHAFIK
                     GFTKAYQVIKDDKLILQMIEEHSSFPVRIIVRPTYIYAKFLSSLLHPKYLKEKEERKRI
                     LSLFQGSSESFEAFKFLHMFEMDDMYKGDVPYFYTNFDKEQVYSSSGEKISYNLLHCCP
                     KQEVINKINSLSTKDMEYQIQLINMALSSIEGNREGNPEFSCYHHVHTIHREISCNTLL
                     QQETNRILERAIIHDRYIQWVSPHLSPNGKLVSGPLNFNIYDGLGGIAIYLVSYAQTFS
                     DSRVDAVLPQVHSTINKLVEKSVYRANASAYYGWPSYYYYSHYMKRTGHLSCDSIKEYE
                     DFAEKLVRDIESYKSLDFIGGLAGLLKVLVNLYNVEKSEIVKKAAEVVKNTIVNKAITK
                     NQGLYWEADHNHSLVLSGFSHGITGICYALSEYVTKVNYDPSLISIIQQALLYEDRFYD
                     ESQHAWEDNRENSSNHSAPLWCHGSAGILLGRGKIKDNLGNEVEVNYLEESLQHTLHSG
                     NKHNQGYSLCHGTLGNLDILNEIRSLDPFRHKEDEITSTIEKWLVDFRRDLEMYNFQNG
                     IKNDFSGVGFMLGITGQLYALLRLKNPSLPSLLLLD"
     gene            complement(13016..13180)
                     /locus_tag="HPB58_RS21455"
                     /old_locus_tag="HPB58_21400"
     CDS             complement(13016..13180)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) L_biotic_A"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017417595.1"
                     /locus_tag="HPB58_RS21455"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HPB58_21400"
                     /product="class II lanthipeptide, LchA2/BrtA2 family"
                     /protein_id="WP_082802525.1"
                     /sec_met_domain="L_biotic_A (E-value: 2.2e-07, bitscore:
                     28.9, seeds: 15, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKKNMKAIEEVSEQELKELAGGAEERAIWTVTIPISLAACPTTQC
                     ASIVSPCND"
     CDS_motif       complement(13115..13180)
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence: MKKNMKAIEEVSEQELKELAGG"
                     /locus_tag="HPB58_RS21455_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       complement(13016..13114)
                     /prepeptide="core"
                     /locus_tag="HPB58_RS21455_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class II"
                     /score="3.30"
                     /molecular_weight="3235.7"
                     /monoisotopic_mass="3233.6"
                     /core_sequence="AEERAIWTVTIPISLAACPTTQCASIVSPCND"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MKKNMKAIEEVSEQELKELAGG"
                     /leader_location="[13114:13180](-)"
                     /alternative_weights="3253.7"
                     /alternative_weights="3271.7"
                     /alternative_weights="3289.7"
                     /alternative_weights="3307.8"
     assembly_gap    13323..13419
                     /estimated_length=97
                     /gap_type="within scaffold"
                     /linkage_evidence="paired-ends"
     gene            complement(<13420..13545)
                     /locus_tag="HPB58_RS21460"
                     /old_locus_tag="HPB58_21405"
     CDS             complement(<13420..13545)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) L_biotic_A"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF038161.1"
                     /locus_tag="HPB58_RS21460"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HPB58_21405"
                     /product="class II lanthipeptide, LchA2/BrtA2 family"
                     /protein_id="WP_243520959.1"
                     /sec_met_domain="L_biotic_A (E-value: 3e-07, bitscore:
                     28.5, seeds: 15, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKNVKAIEEVSEQELKELAGGAEERAIWTVTIPISLAACPTT"
     CDS_motif       complement(13483..13545)
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence: MKNVKAIEEVSEQELKELAGG"
                     /locus_tag="HPB58_RS21460_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       complement(<13420..13482)
                     /prepeptide="core"
                     /locus_tag="HPB58_RS21460_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class II"
                     /score="3.30"
                     /molecular_weight="2153.5"
                     /monoisotopic_mass="2152.2"
                     /core_sequence="AEERAIWTVTIPISLAACPTT"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MKNVKAIEEVSEQELKELAGG"
                     /leader_location="[13482:13545](-)"
                     /alternative_weights="2171.5"
                     /alternative_weights="2189.5"
                     /alternative_weights="2207.5"
                     /alternative_weights="2225.6"
     gene            complement(13574..15715)
                     /locus_tag="HPB58_RS21465"
                     /old_locus_tag="HPB58_21410"
     CDS             complement(13574..15715)
                     /GO_component="GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0008233 - peptidase activity [Evidence
                     IEA]"
                     /GO_function="GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_C39"
                     /gene_functions="transport (smcogs) SMCOG1288: ABC
                     transporter related protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016132308.1"
                     /locus_tag="HPB58_RS21465"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HPB58_21410"
                     /product="peptidase domain-containing ABC transporter"
                     /protein_id="WP_243514176.1"
                     /sec_met_domain="Peptidase_C39 (E-value: 1.7e-24, bitscore:
                     84.3, seeds: 36, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTKRKRKLPVILQTNKYDCGITCLAIVMSGEEKFRLNPKTFRGGR
                     DFIGREGTNLFFLKETAVKYGYTFKAYRTTQLENLAHLVKDAPVILHWNHNHFVVLEKM
                     DNEKALIIDPDSGRSDIPLDEFQEAYSGVAIHVKKDVQSKGESLSSVKEQHSFMKIGKY
                     LFNNKKLISYIILLSFVFQILNLATPFLTQYIVDSFLEGKAEAISLNMLSLFIILSVVL
                     FFVLSFVRMLFIIKLQVYLNKNMTNHFIQKIVSLPLKFFEVNSAGDIATRINNISVIRE
                     VISRLASTLILDISLLIVFCFVMLFYSPILSVIVFAGAFVQVLSTKYLLPKIETYTKQE
                     VNSQAHFQTQLVEILRSMTFIKTIGNTATIEKGMKSSFNQQLTHFSDRMHYSSLLGAIS
                     NSINLSLPLLVLTVGVWWQGQSALTIGAIVAFSSIASRFMTPLGSIIGSLESIKMVEEM
                     VDRVESVLQEDGEQLNQNQPYTFNAKEDSITIRDLTFGYTKESYIFEKAHMEIHPGEKM
                     MIVGKTGSGKSTLLKVISGLYEPTDGEIHYGNQERTKINLKKLRETMGFIVQDINLFND
                     TILNNIKYFNETVSDELAVEAAKQACIHDDIMKMPMGYHTVIGENGISLSGGQRQRIAI
                     ARVLAKQPQILLIDEGTSNLDKETETKILQNIYNKQITVVAITHRTDWLQHADSIYEIK
                     EGKVTLVKQKNKQYLVSGD"
     gene            complement(15731..18883)
                     /locus_tag="HPB58_RS21470"
                     /old_locus_tag="HPB58_21415"
     CDS             complement(15731..18883)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-ii: DUF4135"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-ii: LANC_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1070: lanthionine synthetase C family protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003154890.1"
                     /locus_tag="HPB58_RS21470"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HPB58_21415"
                     /product="type 2 lanthipeptide synthetase LanM family
                     protein"
                     /protein_id="WP_243514180.1"
                     /sec_met_domain="DUF4135 (E-value: 5.4e-94, bitscore:
                     313.7, seeds: 79, tool: rule-based-clusters)"
                     /sec_met_domain="LANC_like (E-value: 3.3e-63, bitscore:
                     211.8, seeds: 47, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNNLTNILISKEKKVNKNDINEDAFFERNLALVYKNDLHLAKESI
                     SHILSVDSLDQIKKLYKTETSKSTFKLSVFKNVAEGISKQKIDSSQIDKRVMFHAFSLK
                     IASYFINLTKTSPQYLLHTSHILEETSFLDNIEKQFQQHILKVCYRTLVFDLNLQREQG
                     NLVGETKKEKYEHYNDVLLTDSTYVYHFFTVYPSLLRIIANEIRKVKKFIGEFLNRYSS
                     DYKLITNKFFSSLQSNKIMTFELGLGDAHSDGRKVAKVSVEQGTIIYKPRNMKVDCLYN
                     ELIAFLDGEIKDKSYKIKTPLVLERENYGWAEYINFEECKSGIDIHTFYQNLGNQIALL
                     YALNAVDFHSENLIAHGSQPVLIDLESLFHVPYEREVKEDAYFKAQQKLNTSVRSLGLL
                     PFFFGGKNVDISGIGRRGKVKSVMKVPQIVNQYSDDMKIERDFIEMNPSMNHPVLKGKQ
                     IYAKDYVEDLKVGFKQMFVKITEHANKLIEIIEKFEANTYVRFIARPTVKYSSLLELSF
                     HPRFLHNSIDREAFLAKLWEESKDSDEYVPLIKHEHSDLMNNDIPYFKVELNSTNLLNS
                     RGKKIPSYFKETPSNLVKSKIRHLSDEDLRFQLNIIELSMLASEDDRQEVIKQFVSKDP
                     SQYEGKKDHKAYLIHKAEQLAMRITKEAYQGVENGKRTYSWMNTTPVGVDEIQWNVSVM
                     GDMLYEGLSGMALMYMALFQATHNENYLDMAEDIMKDIMSRFENIESSLPNGTEISIGA
                     FSGITSIVYTLLNFYAFTKKEQYKTCAKMITKVIPELVEKDKDLDLISGTAGALVVLIR
                     YYEMTGDNETLLLARKCSNHLLSQAIKTEQGLTWKGVAGIPLTGFSHGNAGIIFALHLF
                     YRYCPEKEVEEGIKEGLKFENSYCINENWIDLRKPQEEVASSAWCHGAPGILLSRIELS
                     NSSIPQVAEQAQADMDKALGNIFVDGFGREQSLCHGDVGNSMILLDYGRKMKDEKIIHI
                     SRNLLAESIMSKENGVYQCGIGKTAETPNLMVGFAGMVYGMIYAYHDKLPNLLTLEVNL
                     PS"
     CDS             18902..19015
                     /gene="allorf_4307035_4307148"
                     /locus_tag="allorf_4307035_4307148"
                     /protein_id="allorf_4307035_4307148"
                     /tool="antismash"
                     /transl_table=1
                     /translation="MEREVLAYPSFKYRRTLTIFKRYSVLCSYPVYKTTIV"
     CDS_motif       18902..18928
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence: MEREVLAYP"
                     /locus_tag="allorf_4307035_4307148_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       18929..19015
                     /prepeptide="core"
                     /locus_tag="allorf_4307035_4307148_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class II"
                     /score="-4.60"
                     /molecular_weight="3307.9"
                     /monoisotopic_mass="3305.9"
                     /core_sequence="SFKYRRTLTIFKRYSVLCSYPVYKTTIV"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MEREVLAYP"
                     /leader_location="[18901:18928](+)"
                     /alternative_weights="3325.9"
                     /alternative_weights="3344.0"
                     /alternative_weights="3362.0"
                     /alternative_weights="3380.0"
                     /alternative_weights="3398.0"
                     /alternative_weights="3416.0"
     gene            complement(19037..19213)
                     /locus_tag="HPB58_RS21475"
                     /old_locus_tag="HPB58_21420"
     CDS             complement(19037..19213)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) mature_ha"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003154891.1"
                     /locus_tag="HPB58_RS21475"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HPB58_21420"
                     /product="hypothetical protein"
                     /protein_id="WP_074842839.1"
                     /sec_met_domain="mature_ha (E-value: 4.3e-05, bitscore:
                     21.4, seeds: 5, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEERLYGFAGKLEEELEEIALKEISGGAEQRGISQGNDGHQCTIT
                     WECSICPTHTCWC"
     CDS_motif       complement(19133..19213)
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence: MEERLYGFAGKLEEELEEIALKEISGG"
                     /locus_tag="HPB58_RS21475_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       complement(19037..19132)
                     /prepeptide="core"
                     /locus_tag="HPB58_RS21475_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class II"
                     /score="-2.20"
                     /molecular_weight="3357.7"
                     /monoisotopic_mass="3355.4"
                     /core_sequence="AEQRGISQGNDGHQCTITWECSICPTHTCWC"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MEERLYGFAGKLEEELEEIALKEISGG"
                     /leader_location="[19132:19213](-)"
                     /alternative_weights="3375.7"
     CDS             19244..19402
                     /gene="allorf_4307377_4307535"
                     /locus_tag="allorf_4307377_4307535"
                     /protein_id="allorf_4307377_4307535"
                     /tool="antismash"
                     /transl_table=1
                     /translation="MGFKSISFTINFYIFILIQIFSKFSERFHSENRILFAFFTMIDCN
                     NLHIAVR"
     CDS_motif       19244..19354
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence:
                     MGFKSISFTINFYIFILIQIFSKFSERFHSENRILFA"
                     /locus_tag="allorf_4307377_4307535_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       19355..19402
                     /prepeptide="core"
                     /locus_tag="allorf_4307377_4307535_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class II"
                     /score="-6.50"
                     /molecular_weight="1776.1"
                     /monoisotopic_mass="1774.9"
                     /core_sequence="FFTMIDCNNLHIAVR"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MGFKSISFTINFYIFILIQIFSKFSERFHSENRILFA"
                     /leader_location="[19243:19354](+)"
     misc_feature    complement(19300..19314)
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence:
                     strong, score: 24.45"
                     /tool="antismash"
     gene            complement(19475..20140)
                     /locus_tag="HPB58_RS21480"
                     /old_locus_tag="HPB58_21425"
     CDS             complement(19475..20140)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1016: LuxR family
                     DNA-binding response regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003154892.1"
                     /locus_tag="HPB58_RS21480"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HPB58_21425"
                     /product="response regulator transcription factor"
                     /protein_id="WP_243514183.1"
                     /transl_table=11
                     /translation="MINILLVDDHIGVAQGTKAILEKKGEMEVDILGDSKDTFTAIEEC
                     CYDILLIDLYMPTLNGLELSKQILDKYPNEKILIYTGFDIGTHFNLLVEAGVVGFISKS
                     APEEKIIASIQLALQGETVIPTELFRQLRRTEIASAQGTEPVKEPLIRDLTLNEREQYI
                     LSGVAEGLTNRELSSELLISQRAVEYILTGIFKKLGVKSRTEALIKATKHSLITVRSL"
     gene            complement(20118..21458)
                     /locus_tag="HPB58_RS21485"
                     /old_locus_tag="HPB58_21430"
     CDS             complement(20118..21458)
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1048: sensor
                     histidine kinase"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: protein motif:HMM:NF014567.4"
                     /locus_tag="HPB58_RS21485"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HPB58_21430"
                     /product="ATP-binding protein"
                     /protein_id="WP_243514185.1"
                     /transl_table=11
                     /translation="MKHFTKNSLQEWGAVIFPFLLMNIFLYILFKDILTIQNYMLLVLT
                     GTILLMWYSVMIRRKVKQVETLFKEESKYGKSLFGFLEKGYKENNMENLMHILKNEISS
                     VLNIQNVYVCHYYEEEKVFKTEDDVIADLEHIDLADTYFEVGKLKNIPTGYLFLVGKYR
                     SFSLFIYLKHGKKKIELSYYDVGWLNRMALYTCMTLQTFMLTKDFVKEIEGCELRANHS
                     PFLSKLVFFLSENERIKLSQDIHDTILQELIFIARELEKDAPTQHQVQKIRGKLLENIQ
                     QIRETCYELRPPFLLEMGLVGSIQNLVSKHQEKGNCSIEFLHNLAGEEQISEEITVNLY
                     RIAQELLNNARKHSQAKFIVLSLYKKGSTLLFLYEDDGIGMDMSEHKGEREHFGIKTIR
                     ERTHSLNGKFDLSSSIGEGMLIKVELSIQRNTKTIVEDLIYDKHTVS"
     misc_feature    21493..21506
                     /note="TFBS match to CatR, H2O2-responsive repressor,
                     confidence: medium, score: 21.17"
                     /tool="antismash"
     gene            complement(21503..21694)
                     /locus_tag="HPB58_RS21490"
                     /old_locus_tag="HPB58_21435"
     CDS             complement(21503..21694)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="HPB58_RS21490"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="HPB58_21435"
                     /product="hypothetical protein"
                     /protein_id="WP_243514188.1"
                     /transl_table=11
                     /translation="MEQLFFIIAIASLGIAAVIFIGKILTEGLGGSTFKVSQKSVKIML
                     SFFALYVVTFAVYMFISN"
     gene            complement(21710..22444)
                     /locus_tag="HPB58_RS21495"
                     /old_locus_tag="HPB58_21440"
     CDS             complement(21710..22444)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019393716.1"
                     /locus_tag="HPB58_RS21495"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HPB58_21440"
                     /product="ABC transporter permease"
                     /protein_id="WP_243514190.1"
                     /transl_table=11
                     /translation="MNLLVRNEFMKLKRLKSIYFVFVLSFFPYIVNTVGLFLKATQYDA
                     TKYYMFVFNQYAFLLPAVVFIFSGFYFYIEFKNKTMLNWMSYPFKNFRLIFSKIVATFI
                     VLFSISIVNHILHLATLWIIFQNEQSFNDVLSMFLTSVLFTVLSLCVIPIAALLASITK
                     NIMVVSIAGVLSFFVMTILLGGNVSILFPFSFIYRISMQTFDYEMGYSDFALQAGGSAI
                     FAAYILAAFIGLYVYSKKTRSY"
     gene            complement(22425..23351)
                     /locus_tag="HPB58_RS21500"
                     /old_locus_tag="HPB58_21445"
     CDS             complement(22425..23351)
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019393717.1"
                     /locus_tag="HPB58_RS21500"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HPB58_21445"
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_243514192.1"
                     /transl_table=11
                     /translation="MVNILKAEHINVSLKDKQILKDIDLSFEKGKIYGLLGPNGAGKTT
                     LLKVLLGIFPPTSGEVLFNESNLYKNPKKDVRNSIGSIIEFPGFYDNLTLYENIVLHLK
                     YVQKKMSKQEIYSILNTVGLYEHRDKLFSQTSLGMKQRLGIARAIAHNPSLLLLDEPTN
                     GLDPQGIKEVREMLLKEVRDKGVTAIVSSHLLSEINLMADELIIMNGGEVIFESQFMKN
                     DQEVFLYKMPKHISFHKDIEEQITNYRVTSNGDTHEFIATLPPDQLRVVLKQNGYSAEE
                     IEAYTLSLEDLYLKLITKEKKNEFISA"
     gene            complement(23499..24836)
                     /locus_tag="HPB58_RS21505"
                     /old_locus_tag="HPB58_21450"
     CDS             complement(23499..24836)
                     /GO_function="GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA]"
                     /GO_function="GO:0004673 - protein histidine kinase
                     activity [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_process="GO:0007165 - signal transduction [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1003: sensor
                     histidine kinase"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019393718.1"
                     /locus_tag="HPB58_RS21505"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HPB58_21450"
                     /product="HAMP domain-containing sensor histidine kinase"
                     /protein_id="WP_243514195.1"
                     /transl_table=11
                     /translation="MKLSKKYLLIIVASILFFPISYLGVNFIYYSLLMNVASNNVDIHY
                     EPQKVEAKWKNDIENLQGKSVKDILSFFNNSKEYKEARIVWISTDGDVYFDSSQTPNSK
                     WSIAYTIEFMEKGSKGNDLLLKEELGNGTRNGYAMLEIPEEYVGSKWKILREKYVYVWY
                     LMLLFLWALFIFVSWFFFYGIQRRLIFIQHHMEKEGKDGIPEGFKVKNKDELGQVELSF
                     NKMVEKLKESRRKEIQEEELRKKFISDVSHDLRTPLTIIRGHTFTLSGEKLSPQGKQSV
                     EIINNKISFVGDLIDNLSSFNLLTAQKMPMNRKKVDVLKIIRSSLTAWYPIFEKEGFEV
                     DIGLEKSLIWNIDEVWMKRILDNLFQNIMRHASNGKYVSVRIESDDKHEYLIVEDKGPG
                     LQAKSDHKGSGIGLSIVEIMVKQMGLIQEISSGKNGTTFKIYQKEE"
     gene            complement(24833..25507)
                     /locus_tag="HPB58_RS21510"
                     /old_locus_tag="HPB58_21455"
     CDS             complement(24833..25507)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1008: response
                     regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019393719.1"
                     /locus_tag="HPB58_RS21510"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HPB58_21455"
                     /product="response regulator transcription factor"
                     /protein_id="WP_243514198.1"
                     /transl_table=11
                     /translation="MANTILYIEDDTEIGTFTKAFLESKGFEIIWLKSSYDHEKYLEKA
                     DLVLLDIMIPGLDGFTVGQRIKKRNAETPLLLQTARTSIEDKLKGLNFADDYITKPFHP
                     EELAARIDILLRRFDKVSEDCIEIHHLKVNIKEKRIINVEKDEEILLTEKQLKIFFYLL
                     RHPNQILTKEQIYEMVWERTFIEGDKTLMVHIRHLRQKIEKDPNNPEIVETIRGIGYRI
                     RQ"
     gene            25741..26667
                     /locus_tag="HPB58_RS21515"
                     /old_locus_tag="HPB58_21460"
     CDS             25741..26667
                     /EC_number="3.6.1.1"
                     /GO_function="GO:0004427 - inorganic diphosphate
                     phosphatase activity [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019393720.1"
                     /locus_tag="HPB58_RS21515"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HPB58_21460"
                     /product="manganese-dependent inorganic pyrophosphatase"
                     /protein_id="WP_243514201.1"
                     /transl_table=11
                     /translation="MEKILIFGHKNPDTDTICSAIAYAELKAALGFDVEPVRLGEVNGE
                     TQFALDKFNTSAPRLVETVANEVNSVILVDHNERQQSVSDINDVRVLEVIDHHRIANFE
                     TTDPLYYRAEPVGCTATILNKLYKEHGVEIKKDTAGLMLSAIISDSLLFKSPTCTEQDV
                     KAAKELASIAAVDAEEYGLAMLKAGADLSDKTIAELITLDAKEFQMGEHRVEVAQINAV
                     DTNDVLIRQEDLKHAMLETIAEKGLDLFVLVVTDILNSNSMALAIGKETEAVEKAFDVS
                     LVDDKALLKGVVSRKKQIVPPLTEALS"
     gene            complement(26722..27000)
                     /locus_tag="HPB58_RS21520"
                     /old_locus_tag="HPB58_21465"
     CDS             complement(26722..27000)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019393721.1"
                     /locus_tag="HPB58_RS21520"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HPB58_21465"
                     /product="hypothetical protein"
                     /protein_id="WP_243514204.1"
                     /transl_table=11
                     /translation="MISSHPYIHITKKIKHNRQEYEELEYQLELYEDKIVAGGEQFAIK
                     AVLDVSYRITTKSYGFLYLHTTKGVFSYLVKENPQLFIRHCKEKLNW"
     gene            complement(27324..28235)
                     /locus_tag="HPB58_RS21525"
                     /old_locus_tag="HPB58_21470"
     CDS             complement(27324..28235)
                     /GO_function="GO:0005215 - transporter activity [Evidence
                     IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1166: transporter,
                     EamA family"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019393722.1"
                     /locus_tag="HPB58_RS21525"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HPB58_21470"
                     /product="DMT family transporter"
                     /protein_id="WP_243514207.1"
                     /transl_table=11
                     /translation="MKKTTVYALLVAVMAMWGLNIIWLKLLVNEFAPVTMTAFRIFVAG
                     VAVLLFLSVKGVVRKLTFREFSFICVVSLFNIVGHHYFLSVGLTNTTAMNGGLILGLVP
                     ILTAIASLFLLKVKFSIMKVVGILFAFFGVSFALVAGHGGAISTSYGDVQIFLAAVSQA
                     ISFVLIKKASTNIDARLMTGWLMIVGSAGLFFVSLAVEPQGLATMKTDHYLIWLVFIGS
                     ALLATAFGHMTYNYAMQHIGASESAVFINLNPFFALISSYLFLGESLYITQFIGFLLIV
                     FGVLAGSGAVEQWRRAKVTYKI"
     misc_feature    complement(28712..28721)
                     /note="TFBS match to AbrC3, Antibiotic production
                     activator, confidence: strong, score: 15.22"
                     /tool="antismash"
ORIGIN
        1 aaatctgttg catcagctat cagcttttct cgaagaagag ctccgcctcc tccttttgta
       61 agcgcaaaat gacaatccac ctcatctgct ccgtctatca caacatcaag atgatttact
      121 tcagcaaatg ttacaagagg tatattaaga tcaagagcta gctttttagt ttcttctgat
      181 gtaggaatag ctcttatgtt cattccttct tttacatatt ctccaacctt ttgaatcgta
      241 taataaacag tcgatcccgt accaagtcca acaatcatgc cgtcttttac atattgtgct
      301 gctgcttctc caactgcctt cttttcaatc atttcttcac cttttttccg cataaaattc
      361 atcatcatta taacatcgtt cttattgaaa agaaaaatca tcttccttat ttttcatctt
      421 tcttttccta taatttcata taagaaaagc tttgaccaaa ttcgtcaaag ctttaaaatt
      481 aatcttatcc ttctttttgt actttctttg cataaagcag ttcctcaaga gatgctttga
      541 gtttctttat atcatctaaa gcctcttcta tatactgaga acgctttttt atataactaa
      601 tacgaagaat tttttcaata tcctggcgtt cgtttcctac aaaatctgct ttctccgcta
      661 tgttttctag ctctggctct cttaatatag aaagcttata taaaaagctc tcatgattga
      721 tgagcgtttg aatagttttt atcaaactca gattgtataa ctctgtatgt tgtaaatgac
      781 taaccaactt ctcgagctca acaagcgcca gagcatctat tttaatttct tctttatgtt
      841 tagcaatgtg agaaaagcat tgctctgtca tctgttcata aagcgcttcg attcctgtga
      901 gcacttcact aattttcata acaaattcac atcccctttg taatcaacac aagctttaca
      961 tcctttgtat atgaaaaaaa gatgatgatt agaactctgc ttttctctta tctatataac
     1021 gatggaaaag ctgaaaaaag atatggttct tcagcctcta attcaaatgg cataaggcgt
     1081 gtatcatatg aaatgaactg caattgagaa ggatgatttt cttgtccact aaaacatgca
     1141 agatccattc cctcaaagag ctgctttatg tcattttctc tatcatgaaa aacatttttc
     1201 ccccatgctg ctataacaag atcagcattt cttgttccat aatataaata tcgatctgtt
     1261 tcagcaccta ttgcatcttc cttatctaga tcactaagat catctgcctt ttgagcccga
     1321 taagaaaata aatttaagca ttccacagca ttaaaccccc acttttttgc aaatgtaata
     1381 catttgcttg taacgtaatc ttcacgaact tcgtccgcat tgtccggata aagtgtgata
     1441 aacgcaactt tacgctctct atcatttccc catttacgtt ttaacgaata tctgtatgtt
     1501 cctgtttcat caaaaatagc ttctctcttc atcaaagacc cacctcgtta taaagtagtt
     1561 tcctttcgtc attttattct tattatcatt ccggaaaaca atgacacttt tcaatcgtgc
     1621 ccaaaacaat ttgtttttta tacccatgta catgtaaatt gccactatat gaaagtggga
     1681 aaaacgtatg tagcattaaa aagtgttgta cactataata gaatttaacc tgaaacgttt
     1741 cttcaaaaga aaggatgatt ttcttgagtg aaacacacac attctcacgt ggtgaagaaa
     1801 ttgctaatgc aattacacac ggaattggga ctattttaag tattgttggt cttacgttgc
     1861 tcattgtatt ttctgttcaa tttggggatg tttggcatgt cgttagcttt actgtttatg
     1921 ggacaacaat gctactttta tacacttctt caactcttgt acacagtttt ccacacggac
     1981 gtgttaaaga tttgttcgag atttttgatc attcttctat ttacttgttt attgcgggaa
     2041 cttacactcc gtttttattt gtgattattc aaggaacagt tggatggaca ctttttggag
     2101 ttgtatgggg actagctgta gcaggaatag tatttaaaat tttctttgta aaacgatttg
     2161 ttcttgtctc tacgcttctt tatattgcaa tgggatggct aattgtacta gcatgggatc
     2221 ctcttgcttc ttctctagca ggaccaggtc tgaatctact tgttgtaggt ggagttttat
     2281 atacgatagg aagtattttt tacgtttgga gaggttttcc ttatcatcat gcaatatggc
     2341 acatttttgt tcttggtgga actatcacac attacttagc gatattgcta tacgttcttc
     2401 ctcattagaa tttaggaatt tattaggaaa tcaaaaatga ccctctttct gtaagggtca
     2461 tttttgattt aaaacaaggt cttttgtaag tttaatggta acattccacc ctgcaattat
     2521 ttttctaata taatctcttc atttatctat tttttaaaat ccctcattta tttcttttta
     2581 ataaaataag taagtgtctt tatcgttttg taattatttg aaccaccttc acacattcta
     2641 agactaacag tgtctatgat acaatttagg aaacaaatac aggtgtgtga acattatgat
     2701 tcaaaaaaaa ggaaagctaa tcgttattat tgtattgttc ttctttttta tatatttgtt
     2761 agtcttttca ccatttaatg ctatccaaac gttttatcca gaaagtattc taaacgaaca
     2821 tactctttct gagaagtttg aaaagatgca agttcaaaaa gtggagaaaa aaggaagata
     2881 cacttatatt gttaaaacaa acaaacaaga ctatgttgtt attaaagaat atagctctat
     2941 tatccactat aattggagag tttatccttt tactaaggag gagaactttt agcattcctt
     3001 tattttggag tcatcagctt attacctttg tacatttcat acacatatgg atttgtagga
     3061 gcttctacct ttttaattgt ttgaagtttg agggatggca agataaaacc atcatactct
     3121 ttcttttcaa tcgtgcctgt tgcttcaacc caatcatcat cagcgaattc tttggactct
     3181 ttaacattag caagcgttcc atatacggaa gcatcagcta cacagcatga caatccaaac
     3241 cgcgcaatca caaactcgtc ctttttgaag ttatcctccc gataaataaa ccctttcact
     3301 tccacctttt ttcccacaaa atcttcaaca tgttcttcaa gaatgttcat cattgggata
     3361 tactcttttt ccgttatcgt aattacgtct ttttgtagca tcctctcttt taattcttca
     3421 taatatcctt caggaggttt ctgaggaaca aaccctgctt tatgttcaag tggaatctct
     3481 ccagcttcgg tttgtgcttc ctctacttct ctatttaata cttcatcata gtattgttct
     3541 aaagattcat cacttgttaa ttcttcacgc tgttctacac tcggtctttc tgtgacgttt
     3601 gctccaaatt ttacgcctcg atttttggca acatcgcttg taagagcatg atcaggaaat
     3661 agaaatcctg ttgcaattgg caaaaagaat aggcaataaa cccacagagg agctttacgg
     3721 ctatgatgac atgaacagct cttttgtttt ttgtctgaac cgcttcgcca aatacctaca
     3781 gctcctagaa caaagaaagt aaaagaagcg aaagtaacaa aaccaagcat ttttggtgca
     3841 acaaaagagg aaatatatcc agttagcaac agtttgaaaa taaagagagc aaaaccaatc
     3901 aagagcagtc ctcgaatata gtaatggaag ccttcttcat cgtttttcat gctattcctc
     3961 ctacataata aagttataaa gaaccgttat ggtgtaaaca gatattgtga caacagctat
     4021 aaacattaac acaaatcttt tcttaaaaaa ggccaaatac ataaccgtat ttttcaaatc
     4081 aagcattggt ccgtagatta aaaaggcaag aagtgaacta gctgaaaatg tatctacaaa
     4141 tgaggaagca acaaaagcat ctgcttcaga acaaagagaa agcacgtacc caaagaccat
     4201 catgaccact ggggcgataa aaccatttcc tccaatactc ataagttctc ctctatccaa
     4261 aaacgtttga aaaagacttg cgataaatgc tcctgcaatt aagtattttc ccatatcaaa
     4321 aaactcatca atggcatgaa ataatgtttg acttaatcga tttccatgct gatggggctc
     4381 ttcgacagca gcctcgtctt ttagttgagg attatttttc agaagcttgt acattacaat
     4441 tccaatgatg aaacagagaa taaccgtaag ccccatacgg ccatacacaa tttctttatt
     4501 gcctggaaaa gcatagaaag tagaaaggaa aacaattgga ttaagaatcg gtgctcctac
     4561 gagaagaaca acgcctacgt ggatgggcat tcccttcttt acaagccgtc tgacaacagg
     4621 gataatcgca cattcacaca caggtaaaag tgcactcact acaacacctg aagctaatgc
     4681 tttataagga tttttaggaa tccatttcat taaccattct tcttttacaa acacttgaat
     4741 gattgcagaa gcaaaaacac ctaataaaat aaaaggaatt gcttcaagca gtatacttaa
     4801 gaaaatcgta tttacattca gaaaagcttt tgggaagttc atatcaaaat ctttaacatc
     4861 taaaaagaaa aaagcatagc caaaaaataa gatgagtaag acgcctagta cttcttttga
     4921 aagccgtgat aaagccattt ttttcatcct ttctattaaa aaggtctcgt atacggcgat
     4981 gacttagctc cctttatgct gaaaacaaag aaccttttct attaaaattt aatagttaat
     5041 agatgtatat ggagatacaa aaaatatatg atgctctttt ttgtattgct cattcataaa
     5101 atgtgtgtta gtttaactaa tatgaaaaat aaaacgtaat tattacgatt tacatcacaa
     5161 aatggaaaag gagatattgt tatgttagat tggattgtga ttggcggggg aattcaagga
     5221 acaacaatgg ctcattttct agtacaaata agaaaagttc cgattgagaa attagctatt
     5281 gttgaccctc acaaagcacc gcttgaaaat tggcactctt gtacagaaaa aattgacatg
     5341 tcatttttac gctcaccgtc tgttcatcat cttgatgtgg agccatttag cttgcagaat
     5401 tttgtttcga aaaatcgctc attaactaaa caagatttct atggacgtta taaacgccct
     5461 tccctctatg ccttctctga acattgcaag catcttattc gggacagcaa tcttctacag
     5521 gcatggcaca aaggccgggt tgtttctctt tctagaataa aaaaacattg gatggtcata
     5581 acagaagaag gaaaaaaact tgaaagctta aatattgtgc ttgcaattgg tgttagcgaa
     5641 caaacctatt ggcctgaatg ggctaaatta ttgaaaaaca aggatgcgca atctgttgga
     5701 cacatttttg actcttcttt ttcattgaat aaaagtcaag aaattaccat tatcggcgga
     5761 ggaattagtg ccgcacattt agctattaaa ctaagtaaac aaggacgcag tgttcacctt
     5821 atcactcggc atccgtttcg tattgttgat tttgatagtg acccagcttg gcttggccca
     5881 aagaatcagc ttatgtttag agaggaaaca tcataccaaa aacgccgtgc ttttattaca
     5941 gatgctagac atagaggatc catgccccga gatatttata tcaaattaat tgaacaaact
     6001 cggaagaata acttaacaat tagtaaagat gaaattcaag aggcaaacat aaaagataaa
     6061 aaaatccttt tgtatggaaa aatagctcaa tatgaaacag aaacaattgt attagctact
     6121 gggttttctt cttctcttcc aggaaaagaa tggttaactc ctctgataaa cacggaaaat
     6181 ttacagtgca gtgactgtgg atatcctatt gttagttcat ctctacagtg gagtcataac
     6241 ttatatgttg taggagcatt ggcagagctt gaaatcggtc caatctctcg aaatatttca
     6301 ggagcaaggc aagcagcaga gcaaattgta caatctctat aaaacttttt tatcttttcc
     6361 ccttgataat ttcatgtagc aagggtatta ttgtaatgtt caaatcgtaa taattacgat
     6421 ttttctataa aaggagaatc gtaaatgaaa aaaattggag tcaccgtctt aagtggatat
     6481 ctgggagctg gtaaaacaac attattgcac catattttac ataatgaatc ctctctaaaa
     6541 ctaggagtta ttgtcaatga catgagctct cttaatattg atggatctct tgtaaaaaaa
     6601 gaatacttct ctcatacgaa agagacacta gtggaaatgc aaaacggatg tatttgctgt
     6661 acacttcgag aagatttgct ttatgaggtg gaaaacctca ctaaaattca ggatttagat
     6721 tatatcatta ttgaatcctc aggtattagt gagcctctgc ccgttgctca aactttttct
     6781 tatgaggatg aagaaacagg gatagatctt acagtgaaga catttttaga tacgcttgtt
     6841 acagttgtgg atggattaaa tttcatgaaa gattattgtt caaatgaaga tctttccgac
     6901 cgaaatcaag gatcagatag tacagacgat agaagtattt ctgaacttct cattgagcaa
     6961 attgaatatg caaatgttct tatcctaaat aaaaccgatt tgctatcagc agaaaaaaaa
     7021 gatgagttga aagcactact acgtaagctt aatggagaag ctaagattat tgaagctgtt
     7081 caatgctctg tttctcttga agttattata aacactcgtt cttttgattt tgacaaaatg
     7141 agcctttctc ctggatgggt aaaagaactt aacaatgaac atactcctga aactgaggaa
     7201 tacggaatta cttcctttat atatgaaaaa agacgtccat ttcatgccca gcgtctaatg
     7261 aatttctttg aaacatttcc taatgagata tcgcgttcta aaggtttttt ctgggttgct
     7321 acaagaaatg atgttgcctg tctcctttca caagcaggcg gttctatgac aattagtgaa
     7381 gcaggaaaat gggtaaatac tctttcagat gaagataaag aagacataga actgtcgagc
     7441 agatttcacc ctacttatgg agacagactg acagagcttg tatttatcgg aatcaaaatg
     7501 aacaaaaaca aaattataaa tgctttagac gcatgcttac taacaaatga agaaatgaaa
     7561 aaggactggt ctactttcaa tgatccactt ccttcattct tgattcaata aaaggagaag
     7621 atacaatgaa aaaattaatg atgttatgca gtgttatgct tttatttgct ttatttctag
     7681 caggttgcgg aaacgaagac agcagttctt ctgagaagaa gagcgacgga aaactcacca
     7741 tttatacaac aatctatccg attgaagact ttacaaagaa aattggtgga gataatgtta
     7801 ccgtaaaaag cgttatccct aacggtgttg atgctcattc ttttgagcca acaacaaaag
     7861 atatgctaaa aatcgctaaa gctgatgcgt tcatttactc tggagcaggt gcggaaggtt
     7921 ttgctgatgc agctaataaa acgttgaaag atgaagatgt gaaaatgatt aaagcagctg
     7981 aaggcgcgga gcttgttgct ggtcatgatg atcatgacca cgagcatgga gaagaacatg
     8041 gtgatgagca tgaacatggc gaccttgatc ctcatttttg gcttgatcca cagcgttcta
     8101 tcgtcatggc tgagaatatt aaaaatgcat tatctgaact agagccaagc aaaaaagatg
     8161 agtttgaaaa gaattttaac caagtaaaaa ctgatttaga agaacttgat aaaaaatatg
     8221 aagaagctat taaaaatgct ccttcaaaag aaattttagt ttcacatgct gcatatggct
     8281 actgggaaga tcgctatggt attgaacaaa taagcgtttc tggactttct ccaactcaag
     8341 aaccttcaca aaaggaacta aaggagattg tagaaacagc aaaagagcac aatatcaaat
     8401 acgttatctt tgatgcaaac gtaacaaata aaattgccac tcttgttcgt aaggaaatcg
     8461 gtgcagagtc tcttacatta aataatatgg aaacacttag agaccaagac cgtgaaaacg
     8521 gggaagatta ctttagccta atgaataaaa acttggaagc tttgaaaaag gcgctaaaca
     8581 gtaaataaag gaaaacccca aggatgtatc cttggggttt tattttattg ctttataagt
     8641 atttaaagct tttatatttg tttccgcaga tcttttgctt ttttgaagga gtttttgctt
     8701 tgctttttta ggattgtctt ttaaattgta ttgatcaatg ataagcgcca atgttccaga
     8761 tacttttgga gctgctgaag aagtacctgc catataaata tatcctccct ttggagacgt
     8821 gctaagcact tgttctttca taaaaagctc catttttctc catttctcaa ctccatatgt
     8881 ttgaaggagc ttaatatccc ctcctggtgc tgataaatca acataacgac ccctatttga
     8941 aaaaacagaa agttctttag caggacctgt tgaagttact gcaactacac ccttaatatg
     9001 agcaggtaca tctaaaagat gtcctttcac tttagcatga ttaagttgaa aatgggattt
     9061 catgaaggaa gatacctcgt tcttgttatt aaaattaact gaatcattac caacagaagc
     9121 gacaactacg cttccctttc cttctgcaaa cataactgct ttttcataag ccaagatttc
     9181 agcaagttga cttttcgaac ttccgccttc ttcattcata tgttcagaag tcagatattc
     9241 tcctaaacta agattaataa catctacatc atcttttgca gcctcaataa ttcctttaat
     9301 aatccaaata gattcagcag aagaagttcc aaatactcgg tatgatttaa ggctagtttg
     9361 cggtgctact cctttcacta ctccgtttgc agccacttgc cctgcgacat gtgttccatg
     9421 tcccgtcata tcttcaatat tatttattat tcctttttca gactgttcgg tttcacgaaa
     9481 cccaccttga ggaaccagat ttttagatcc ctttattata ttttttttaa gagaaggatg
     9541 atctgcatca atcccagaat caataattcc cactaccact tttttagaac cttcagaaat
     9601 ggtataactc tttccattgt ttgtaatctc tttcatatcc cactgcctgt cccaaagcga
     9661 gctcggggct cccacgacat ctgactgttt agtagaaaat tcagatggag cagcttttaa
     9721 agaatagtta tatgtctgga ccattttatt tccatctaat atctgaacct cagcttcact
     9781 tgcttttatt tggattaatc cgatttcctt caccacatac gttatgttca tattgtgctg
     9841 ttgggcttct cttagaaact cttccgtata ttctggttta cttaataata cgctatagta
     9901 ggaagttcca tctgcttgta cttctgcatt tatacataaa aagagaatac tacaaaaaag
     9961 aagtgatata agattctttt ttttcactgt tttccgctcc ttaatcgagt agtagtagtg
    10021 atggaaggga tgggtttttt aatctgagca gcgcataaag ctgacctgtg attccaagca
    10081 taaagcctac tcccgaaaaa tcattcttaa tgccattttg gaaattgtac atttctaaat
    10141 ctctacgaaa gtctacaagc cacttctcta ttgtgctagt aatctcgtct tctttatgac
    10201 gaaaaggatc aaggcttcta atttcgttca agatatctaa attccccaat gtaccatgac
    10261 aaagagaata gccttgatta tgtttatttc cactatggag cgtgtgctgc aaagattctt
    10321 ctagatagtt gacttctact tcatttccta agttatcctt aatcttacct cttccaagta
    10381 gaattcctgc tgaaccatga caccatagag gagcggaatg attagaagaa ttctccctat
    10441 tgtcttccca tgcatgttgc gactcatcat aaaagcgatc ttcataaaga agagcctgtt
    10501 gaatgatcga gataagcgaa ggatcataat tcactttcgt tacatattca ctcaatgcat
    10561 agcatatacc tgttattcca tgtgaaaatc cacttaggac tagactatga ttatgatcag
    10621 cttcccaata aagaccctga ttctttgtga ttgctttatt tacaatagta ttcttcacga
    10681 cttccgctgc tttttttaca atttcactct tttctacgtt gtaaaggttc acgagcactt
    10741 ttaataaacc agcaagtccc ccaataaaat ctaaactttt ataggattca atatctctaa
    10801 ctaatttttc agcaaagtct tcatattcct ttatagaatc acaagataga tgacctgtcc
    10861 tcttcatata gtgactataa taatagtaag aaggccaacc ataatatgca gaagcgtttg
    10921 ccctatatac actcttttct actaacttgt tgattgtact atgaacctgc ggaagtactg
    10981 catcaactcg tgaatcagaa aatgtctgag catatgagac caagtaaata gctattccac
    11041 cgagaccgtc ataaatatta aaattcagag gacctgatac aagttttccg tttggactaa
    11101 gatggggaga aacccactgt atatatcgat cgtgaattat ggctctttcc aaaatacgat
    11161 ttgtctcttg ctgaagtaat gtgttgcacg atatttctcg atgtattgta tgaacatggt
    11221 gatagcaaga aaattccgga tttccttccc tatttccttc tatactgctt aatgccatat
    11281 tgataagttg gatttgatat tccatatctt ttgttgataa agagtttatt ttattgatta
    11341 cttcttgctt agggcaacaa tgcaggaggt tataagaaat cttctctcca ctactactgt
    11401 agacttgctc tttatcaaaa tttgtataaa agtaaggaac atccccttta tacatgtcat
    11461 ccatttcaaa catatggagg aatttaaaag cttcaaaact ctccgatgac ccttgaaaaa
    11521 gagaaagaat tcttttcctt tcctcttttt cctttaaata tttagggtgc agcaacgaac
    11581 ttaaaaattt agcatatata tatgttgggc gtacaataat tcggacagga aaagaagaat
    11641 gttcttcaat catctgtaaa attaatttgt catcctttat aacttgatag gctttcgtaa
    11701 atccttttat aaaagcatgt tcatacccga atatctctat tccattatct ttataaattg
    11761 gtaagttcgt tcctcttcca aatttagttt cttgaaactc cacggcaatc ttatctgtct
    11821 tattgttcac aacaatttcc ttattgaaag tgtgaagctc aatatttgtt aatccactta
    11881 tatctaccac ataattttct tccggatagc ttgtatgagt aaagaaagta gatttataaa
    11941 ctgtacgatt aatagaagat gaaactttta atacagagtc tttctttgat tcctctgtaa
    12001 agtaaagagt actttgaaaa agagtttcaa gatcaattaa gacaggatgt aagccgttac
    12061 atataatatt ttcataatga aaatcagatc cttgaaaagc ataaataaac gctagatgca
    12121 ttcctaattc ataataataa tttgatacct catcaagtgt ctgacaagag gttgattcta
    12181 tatactcttg gaaaccatag ttatttttgc ttatcataat aggtgttttc agcttggtgt
    12241 catattgatg attaaaatat ttaatcatct tttgatataa ttgatctcct tctaatgaac
    12301 gaggtttata aacaattttt ccgcattcac atgttaaaat agctacgctt ttcccttcac
    12361 aatgagaatc gcctgcgtct acttttatag ataagagccg accaagttgt tgatgaaatg
    12421 tttcagctat ttcttcataa tgagctatgt atgcttttat aatggataag ctgtattgga
    12481 taaattgatt agaagtccta tccatcattt cactaagtac aggatacttc tttagtatgt
    12541 tctccacagc actgtaatta gagaaagtgt cattaaagcg acgatagaaa aaatcttctt
    12601 ctctatggaa ttcatcaaac atttcgtgaa attcatatat aactgttttt cttgccaatt
    12661 tatacaacat cttcttatat tgaatgatta gagaatacaa taacgatttt aaatcaaaaa
    12721 aactctgatt caatcgtcct agctccttca ctaatttttc cgaaaagcgc tctgtaaaat
    12781 gagtataaaa tgaagggaat tcatcttctt cagtaaaggg ggtaaattga aatttttgat
    12841 ttccaaggaa aactgtgtta aagtggggag gataaaattt agatttataa aacaacttca
    12901 tagctatcac atcctattta tcataataat cgggtgcata aaggcacccg attctgtttt
    12961 cgtattttag gcgacaaagc taaagatatg tacggccata catattttta gctttttagt
    13021 cgttgcacgg tgatacgatt gatgcacatt gtgttgttgg gcatgctgct agagaaatgg
    13081 gaattgtaac tgtccaaatt gctctttctt ctgctccacc tgctaattct tttaactctt
    13141 gctctgatac ttcctcaatt gctttcatgt tttttttcat ttttatttcc tcctttaatt
    13201 ttttatttag tcgttgcacg gtgatacgat tgacgcacat tgtgttgttg ggcatgctgc
    13261 tagagaaatg gggattgtaa ctgtccaaat tgctctttct tctgctccac ccgctaattc
    13321 gtnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    13381 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnt gttgttgggc atgctgctag
    13441 agaaatgggg attgtaactg tccaaattgc tctttcttct gctccacccg ctaattcctt
    13501 taactcttgc tccgatactt cttcaattgc tttaacgttc ttcatttgtt ttcacctcct
    13561 ttcaagtgat gttttaatct ccgctcacta aatattgttt atttttctgc ttcacaagag
    13621 ttacttttcc ttccttaatc tcataaatag agtcagcatg ctgaagccag tctgttcgat
    13681 gtgtaatagc aactacagta atctgtttat tataaatatt ctgcaatatt ttcgtttcgg
    13741 tttccttatc taagttgctt gttccctcat caataagtaa gatctgaggc tgttttgcta
    13801 atactctcgc aatagcaatt ctctgtctct gacctcctga caaactaatt ccattttctc
    13861 caataacagt gtgatatccc attggcattt tcataatatc atcatgaata caagcttgtt
    13921 tggcagcctc aacagccaat tcatcagaaa cggtttcatt gaaatatttg atattattta
    13981 aaatggtatc gttaaataaa ttaatatctt gaacaatgaa tcccatcgtt tcacgcagtt
    14041 tcttcaagtt aatctttgtt ctctcttgat ttccatagtg aatttcacca tctgttggtt
    14101 catataagcc tgagataact tttagaaggg ttgattttcc acttcctgtt ttaccgacaa
    14161 tcatcatctt ttcccctgga tgaatctcca tatgagcttt ttcaaaaata taactttctt
    14221 ttgtgtagcc aaacgttaag tctcgaatag taatggaatc ttccttagca ttaaatgtat
    14281 aaggttgatt ttgattaagc tgttcaccat cttcctgtaa tacagactct actcgatcga
    14341 ccatttcttc caccatttta atagactcta agctaccgat aatagagcca agcggcgtca
    14401 taaatctact agcaatacta gaaaaagcta caatagcccc aattgttaag gcagactgcc
    14461 cttgccacca tactccgact gttagtacaa gaagaggtag ggataaatta atcgagtttg
    14521 aaattgctcc taataaagat gaataatgca ttcggtctga gaaatgagtc agttgttgat
    14581 taaatgaaga tttcattcct ttttcaattg tagctgtatt accaattgtt ttaataaatg
    14641 tcatagatct taatatttct acaagctgcg tctggaaatg tgcctggcta tttacttctt
    14701 gttttgtgta cgtttctatt ttgggtaaga ggtattttgt actaagcact tgaacaaagg
    14761 ctccagcaaa tacaatgaca gataaaatcg gtgaataaaa taacattaca aaacaaaata
    14821 caataagaag actaatatct aggattaagg tagaagcaag tcgtgagatg acctctctaa
    14881 tcacagagat attattaatt cgtgttgcaa tgtctccagc tgaattgact tcaaagaact
    14941 ttaatggcag tgagacaatc ttttgaataa aatgatttgt catattttta ttaagataaa
    15001 cttgtagctt aataataaac agcatcctca caaacgaaag aacgaagaac aatacaacag
    15061 ataaaataat gaatagtgaa agcatattaa gagagatggc ctctgctttc ccttctaaaa
    15121 atgagtctac aatatactga gttaaaaaag gcgttgctaa gtttaagatt tggaaaacaa
    15181 aagaaagtaa gataatgtaa gaaattaatt tcttattgtt aaaaaggtat tttccaattt
    15241 tcataaatga atgttgttct tttacagagg aaagagattc ccctttagat tggacatcct
    15301 ttttaacatg aatagcaacc ccgctataag cttcctgaaa ttcatctaaa ggaatatcac
    15361 tgcgacctga gtcaggatca atgatcaacg ctttttcgtt gtccattttt tcgagaacaa
    15421 caaagtgatt atgattccag tgcaagataa caggggcatc tttaacaaga tgagctaagt
    15481 tttcgagctg agttgttcga taagctttaa aggtatagcc gtattttaca gcggtctcct
    15541 ttaaaaagaa taaatttgtt ccttcacgtc caataaaatc tcttccacct ctaaaagttt
    15601 tagggtttaa tctaaatttc tcctcaccgc tcattacaat agccaaacag gtaattccac
    15661 aatcatattt atttgtttga agaataacag gaagctttct ttttcgtttt gtcattttac
    15721 tttcccctct ttaagaaggt aggttaactt ctaaagttaa aaggttcggt agtttatcat
    15781 gataggcata aatcatgcca tacaccatgc cagcaaaacc taccattaaa tttggtgttt
    15841 ctgcagtttt tccaattcca cattggtaaa caccattttc tttactcata atactttctg
    15901 ctaacaagtt tcgagaaatg tgaattatct tttcatcttt catttttctg ccatagtcta
    15961 gtaaaatcat tgaattccca acatctccat gacataagct ttgttctctc ccaaatccat
    16021 ctacaaaaat gttacctaaa gccttatcca tatcagcttg agcttgctct gctacctgtg
    16081 gaatcgaaga gttacttaat tcaatcctgc taagtaggat tcctggtgct ccatgacacc
    16141 acgccgaaga tgctacttct tcctgaggtt ttctaagatc tatccaattt tcgttaatac
    16201 aataactgtt ttcaaatttc aatccttctt taatcccctc ttctacttct ttctcagggc
    16261 agtaccgata gaagagatga agcgcaaaaa taataccagc gtttccatga gaaaatcctg
    16321 tgaggggaat tccagctacc cctttccaag ttagtccttg ttctgtttta atagcttgac
    16381 tcaaaagatg atttgaacac ttcctagcta aaagcaacgt ctcgttgtcg ccggtcattt
    16441 cataataacg gataagaaca actaaagctc ctgccgttcc actgataaga tccaaatctt
    16501 tatctttctc aacgagttct ggaatgacct tcgttatcat tttcgcacat gttttgtact
    16561 gttctttttt tgtaaatgcg taaaagttaa gaagagtata aacaatagaa gtaatgcctg
    16621 aaaaagcccc gattgatatt tctgttccgt taggtaaact agactcaata ttttcaaacc
    16681 ttgacataat atctttcata atgtcttctg ccatatctaa gtagttttca ttatgagtag
    16741 cctgaaataa agccatatac atcaaggcca tccctgataa accttcatag agcatgtcac
    16801 ccataaccga aacattccac tgaatttcat cgactcctac tggtgttgta ttcatccagc
    16861 tatatgttct ttttccattc tctactcctt gataagcttc cttagtaata cgcatggcta
    16921 attgttctgc cttatgaatt aaataagctt tatggtcctt ttttccttcg tattgtgagg
    16981 gatcctttga aacaaactgt ttaataactt cttgacgatc atcctctgaa gcgagcattg
    17041 ataactcaat aatatttaat tgaaacctta aatcttcatc actcaaatgt cttatcttac
    17101 ttttcacaag gttactaggt gtttctttaa aataggaagg aatctttttt cctcgtgaat
    17161 tgagaagatt tgtggagttt agttctacct taaaataagg gatatcattg ttcattaaat
    17221 cactatgctc atgtttgata agtggcacat attcatcgct atcttttgac tcttcccata
    17281 gttttgcaag aaaagcttca cgatcaattg aattgtgtaa aaaacgtgga tgaaagctta
    17341 gctctaaaag agaactatat tttaccgttg gtcgtgcaat aaaccgaaca taagtattcg
    17401 cttcgaattt ttcaataatc tctatgagct tattagcatg ttctgtgatt tttacaaaca
    17461 tttgtttaaa gcctactttt aaatcttcta catagtcttt tgcgtaaatt tgctttcctt
    17521 ttaaaacagg atgattcata gaaggattca tttcaatgaa gtcccgttca atcttcatat
    17581 catctgagta ttgattaaca atttgaggaa ctttcattac agatttcact tttccccttc
    17641 gtccaattcc gctaatgtct acattctttc ctccaaaaaa gaacggaaga agacctagag
    17701 aacgaacaga tgtattcaat ttttgctgag ctttaaaata ggcatcttcc ttcacttctc
    17761 tttcatatgg aacatgaaat aaagattcaa gatcaataag tacaggctga gaaccatgcg
    17821 caattaaatt ttctgaatga aagtcaacag cattcaaagc atataaaagc gcaatttggt
    17881 tacctaagtt ttggtaaaag gtatgaatat ctatgccgct cttacattct tcaaaattga
    17941 tatattcagc ccacccatag ttctcccgct ctagaactaa cggcgtttta attttataag
    18001 acttatcttt tatctctcca tctaagaaag caataagctc attatataag caatcaactt
    18061 tcatatttcg tggcttgtag attatcgttc cttgctcaac agaaactttc gctactttgc
    18121 gaccatctga atgcgcatcc ccgagtccta gctcaaatgt cataatttta ttgctttgta
    18181 atgatgaaaa aaatttattt gtaattagtt tataatcact gctatagcga ttaagaaatt
    18241 cccctataaa tttttttact tttcttattt cattagctat aattcttagc aaacttgggt
    18301 atactgtaaa gaaatgataa acgtatgtgc tatctgttaa taagacgtca ttatagtgct
    18361 catatttctc tttcttggtc tcaccaacaa gatttccctg ttctctttga agattcaaat
    18421 caaaaacaag cgttctgtag cacactttta aaatatgttg ttgaaactgc ttttctatgt
    18481 tatctagaaa actagtttct tctagaatat gtgacgtatg taataaatat tgaggcgacg
    18541 tttttgtaag attaataaaa taagacgcga tttttaaaga aaaagcatga aacatcactc
    18601 ttttatcaat ttgggaagaa tcaatttttt gtttggatat tccctcagca acattcttaa
    18661 atacgcttag tttaaaggtg gatttagaag tttctgtttt gtacagtttt tttatttgat
    18721 ctaatgaatc cactgaaagt atatgagaaa tgctttcttt tgctaaatga agatcatttt
    18781 tatacacaag agcaagattt cgttcgaaaa aagcatcttc atttatatcg tttttattga
    18841 cttttttctc tttacttatt aagatgttgg ttaagttatt cattccgctc actccttatg
    18901 tttggaaaga gaggtactgg catacccctc ttttaaatac agacgtacac tgaccatatt
    18961 taaacgctat agtgttttat gtagctaccc cgtttacaaa actactatcg tttaaaaacg
    19021 gccatcctag gagttactag caccagcacg tatgagtagg acaaatactg cattcccaag
    19081 taattgtaca ctgatgtcca tcgttacctt gtgaaatgcc tctttgttct gctccaccac
    19141 taatttcttt aagcgcgatt tcttctaact cctcttctaa ctttccagca aatccataaa
    19201 gtctttcttc cacatctgcc acctcctaat aatttagaaa ttaatgggtt ttaaatccat
    19261 ttcttttacc atcaatttct atatttttat attaatacaa attttctcaa aattcagcga
    19321 aaggtttcat tcggaaaacc gcattctttt tgcgttcttt acgatgatag attgcaataa
    19381 tctacatatt gctgttcggt aacgcaaata taaaagagca agaaccttta agaggattct
    19441 tgctctttta tattttcagc ttgtcctttg tatttcacaa acttctaacc gtaattaatg
    19501 aatgtttcgt tgcttttata agagcttcgg tacgggattt aacaccgagc tttttaaaaa
    19561 tccctgtaag aatatattct actgcacgct gactaattaa caactctgaa gataattctc
    19621 gatttgttag cccctctgct actcctgata aaatatattg ctctcgttca tttagcgtaa
    19681 gatctcttat taagggctct tttactggct ctgtaccttg tgcagatgca atttcagttc
    19741 ttcgaagttg gcgaaacagt tcagtaggaa tgaccgtctc accttgtaaa gctaattgaa
    19801 tagaagctat aatcttttcc tctggagcag acttactgat aaaaccaaca actcccgctt
    19861 caacaagaag attaaaatgg gttccaatat cgaagcccgt ataaattaag attttttcgt
    19921 ttggatactt gtccaaaatt tgtttcgaaa gctctaagcc gtttaaagtt ggcatataca
    19981 aatcaataag tagaatatca tagcagcatt cttcaatggc tgtgaacgta tctttactat
    20041 cacctaaaat atctacttcc atctcaccct ttttttctaa aatagctttt gtaccttgag
    20101 caacgcctat atgatcatca actaacagta tgtttatcat aaataaggtc ctccactatt
    20161 gttttggtgt ttctttgtat gcttaattca actttaatca acatgccttc tccaatacta
    20221 gaagagagat caaattttcc atttaaacta tgagtacgct ctctaatcgt tttaattcca
    20281 aaatgctctc tttcgccctt atgttcactc atatccattc ctataccgtc atcctcatat
    20341 aaaaataaaa gagttgagcc ttttttataa agtgataaaa caataaactt agcttgtgaa
    20401 tgctttcttg cattatttag taactcttga gcgattcggt aaagatttac cgttatctct
    20461 tcactgattt gttcttcacc tgctaagtta tgaagaaatt caattgaaca atttcctttt
    20521 tcctgatgct tagacacgag gttttgaata ctgcctacaa ggcccatctc tagtaaaaaa
    20581 ggggggcgaa gttcataaca agtttccctt atttgttgga tattttcgag tagctttcct
    20641 cttattttct gtacttgatg ttgtgtagga gcgtcttttt ctaattctct agctataaaa
    20701 atcagctctt gaagaatagt atcgtggata tcttgtgaaa gtttaattcg ttcattttca
    20761 gacagaaaga aaacgagctt gctcaaaaag ggagaatgat tagctcttaa ttcgcatcct
    20821 tcaatttctt taacaaaatc ttttgtaagc ataaatgttt gtaatgtcat acatgtataa
    20881 agagccattc ggtttagcca acctacatca taataactca gttcaatctt ctttttgccg
    20941 tgcttcaagt aaatgaaaag agagaaagag cgatattttc ctactaaaaa aagatagcca
    21001 gtggggatat tttttagctt tccaacttca aaatacgtat ctgctaggtc aatatgctcc
    21061 aagtctgcta tcacatcatc ttctgtctta aacactttct cttcttcata gtaatgacac
    21121 acatacacat tttgaatgtt caatacactt gaaatttcat ttttaagaat gtgcatcaaa
    21181 ttttccatat tgttttcttt ataacctttc tctaaaaagc caaacaaact ctttccatac
    21241 tttgattctt ccttgaacag tgtctcaact tgtttgactt tccttctaat cataaccgaa
    21301 taccacataa gaagaatggt tcccgttaat acaagcagca tatagttctg aatcgttaat
    21361 atatctttaa agagaatata aagaaagata ttcataagca agaatgggaa tattacagct
    21421 ccccattctt gcaaactatt tttagtaaaa tgcttcattt tacaccatcc ttcttctaaa
    21481 cggtaagtag cctggaaagt ttctaattac taataaacat ataaacggca aatgtaacaa
    21541 catataaagc aaagaagctg agcattattt tcacagactt ttgagagacc ttaaaagtgg
    21601 aacctcctaa accttctgtt aatatctttc cgataaaaat aaccgctgct attccaagtg
    21661 atgcaatcgc tatgataaaa aatagttgtt ccattacagt ttcctccttt taataacttc
    21721 ttgttttctt tgaataaaca tataaaccga taaaagcagc caaaatataa gcagcaaaga
    21781 tagcagatcc tccagcctga agggcaaaat cactatatcc catttcataa tcaaatgttt
    21841 gcatactaat gcgataaata aaggagaacg ggaacagtat cgaaacattt ccacctagaa
    21901 gaatcgtcat cacgaagaaa gataaaactc ccgcaatcga aacaaccatg atattttttg
    21961 tgatagatgc aagtaaagcg gcaataggaa taacacataa actcaagact gtaaacaaaa
    22021 cagaagttag aaacattgat aatacgtcat taaaactttg ttcattttga aagatgatcc
    22081 ataatgttgc caaatgtaaa atatgattca caatggaaat actaaataaa acaataaatg
    22141 tagcgacaat ctttgaaaaa ataagccgaa aatttttaaa cggataggac atccaattta
    22201 gcatcgtttt attcttaaat tcgatataaa aataaaaccc tgaaaagata aacacaacag
    22261 ctggtaataa aaaggcatac tgattaaaga caaacatata atacttggtg gcatcatact
    22321 gagttgcctt taaaaacagc cctactgtat ttacaatata agggaagaaa cttagtacaa
    22381 aaacaaagta aatggatttt aatcttttta atttcataaa ttcattacgc actaataaat
    22441 tcatttttct tctcctttgt tataagtttt aaatataaat cttctaaaga aagcgtgtaa
    22501 gcttctattt cctctgctga atagccattt tgttttaata cgactcgcaa ttgatcaggt
    22561 ggaagagttg caataaactc gtgagtatct ccattgcttg tcactctata gtttgtaatt
    22621 tgttcttcta tgtctttatg gaaggaaata tgcttaggca tcttatatag gaaaacttcc
    22681 tgatcatttt tcataaactg agattcgaaa ataacctctc cgccattcat aataatgagt
    22741 tcatcagcca taagattaat ttcacttaaa agatggcttg atacgatagc tgttactcct
    22801 ttgtcacgca cttcttttaa caacatctct ctaacttcct taattccttg tggatcaagt
    22861 ccatttgttg gttcatcaag taataaaaga cttggattgt gagcaattgc tcttgcaatg
    22921 cctaaccttt gcttcattcc aagcgatgtt tgagaaaaaa gcttatctct gtgctcgtaa
    22981 agacctaccg tatttaaaat cgaataaatc tcctgcttag acattttctt ttgaacgtat
    23041 tttaaatgta gaacaatgtt ttcatacagc gttaaattat cataaaatcc tgggaattcg
    23101 ataatgctac caattgaatt tcttacgtct ttttttgggt ttttatatag gttagattca
    23161 ttaaataaaa cctcgcctga tgttggggga aatataccga gcagtacttt taacaacgtt
    23221 gttttccctg ctccatttgg tcctaacagt ccataaatct ttcctttttc aaatgacaaa
    23281 tcaatgtctt ttaaaatttg tttatctttt aaagaaacgt taatgtgctc tgcttttaaa
    23341 atattaacca tcaacttttc tctcccttcg ctttcctttt gttactttta gtatagacac
    23401 gctaatttaa attaagggtt gatttcagtt taaatttcgt ttaaatttca ttctattttc
    23461 ttaccacaat aaaaaaagac tgccttctta ggcagccttc attcttcttt ttgataaatc
    23521 ttaaaagtag taccattctt cccacttgaa atttcttgta ttaatcccat ctgctttacc
    23581 ataatctcca caatggatag accaattcct gaacctttat gatctgactt cgcctgtaaa
    23641 ccaggacctt tatcttctac aataaggtac tcatgtttat catcactttc aatacgcaca
    23701 gatacatatt ttccattgct cgcatgtctc ataatatttt gaaacaagtt atctaaaata
    23761 cgcttcatcc acacttcatc aatgttccaa attaaacttt tttctagacc aatatcaact
    23821 tcaaatccct ctttttcaaa aattggatac caggctgtta gcgacgaacg aataattttt
    23881 aatacatcta cctttttcct gttcataggc attttttgag ctgttaacaa attaaacgaa
    23941 gataagttat caatcaaatc cccaacaaaa ctaatcttgt tattaataat ttcaacagat
    24001 tgctttcctt gaggggacaa cttttctcca cttaaggtaa acgtatgccc tcttataatc
    24061 gtaagtggtg ttcttaaatc atgagaaacg tctgaaataa atttctttcg tagctcttct
    24121 tcttgaattt cttttctccg gctttctttt aatttctcta ccattttatt aaaagaaagc
    24181 tccacttgac ctagctcatc tttatttttc actttaaatc cttctggaat tccatctttc
    24241 ccttcctttt ccatgtggtg ttggataaaa ataagacgtc tctgaatccc ataaaagaaa
    24301 aaccatgaaa caaaaataaa taaagcccat aggaataaca acatcaaata ccatacatat
    24361 acatattttt cacgtaagat tttccacttc gagcctacat attcttcagg aatctctagc
    24421 attgcgtaac cgtttcttgt cccgttacca agctcttctt tcaacaaaag atcgttcccc
    24481 ttactgcctt tctccataaa ttcaatagta tatgcaatag accattttga atttggcgtt
    24541 tgagaagaat caaagtatac gtctccatcg gtactaatcc aaacaattcg cgcttcctta
    24601 tattcttttg agttattaaa aaatgataga atatctttta cgctttttcc ctgtaaattt
    24661 tctatatcat ttttccattt tgcttcaact ttctgaggct cataatggat atcaacatta
    24721 ttgcttgcca cattcataag aagggaataa taaataaaat tgactccaag gtaggaaata
    24781 ggaaaaaaaa ggattgacgc tacaataata agtagatatt ttttagaaag cttcattgtc
    24841 taattcgata cccaattcct cggatcgttt ccactatttc aggattattt gggtccttct
    24901 caattttttg tcgcaaatgt cttatatgca ccataagcgt tttatcccct tcaatgaatg
    24961 ttctttccca taccatttca tagatttgtt ctttcgttaa aatttggttt ggatgacgaa
    25021 gcaaataaaa gaaaatttta agctgttttt ctgttaataa aatctcttca tctttctcaa
    25081 cattaataat acgcttttct tttatattta ctttaagatg atggatttca atgcagtctt
    25141 cacttacttt atcaaaacgc cttaaaagaa tatcaatccg ggctgcaagt tcttcaggat
    25201 gaaatggttt agtaatataa tcatccgcaa aatttaaccc ttttaacttg tcttcaattg
    25261 aagttcgagc tgtttgtaac aaaagaggag tttcagcatt tctcttttta atacgctgtc
    25321 caaccgtaaa gccgtccaaa ccaggaatca taatatctaa caataccaag tctgctttct
    25381 ctaagtattt ttcgtgatca tatgatgatt ttaaccaaat gatttcaaat ccttttgatt
    25441 ctaaaaatgc ttttgtaaaa gtaccaattt ctgtatcgtc ttctatgtag agaatagtgt
    25501 ttgccaatca gcttccctct ttcattagaa tttttaatct agcttacttt ttatccttat
    25561 tctaacaaat aaaaatcggt atatctcctt cttttctata ataaaaaatg atagttaagc
    25621 tctatttcat atcagtcaat aaaaaagaat aatttttgcc taagactttt ttacaaactg
    25681 agagagatgg tatagtatgt atgtatactt attttacata taggaaaaag gagattaatt
    25741 atggaaaaga ttcttatttt cggtcataaa aacccagata cagacacaat ttgctcagct
    25801 attgcttacg ctgaattaaa agcagctcta ggctttgacg ttgaacctgt tcgcttagga
    25861 gaagtaaacg gagaaactca atttgcttta gacaaattca acacttcagc acctcgtctt
    25921 gtggagactg tagcaaacga agtaaacagc gtaatcttag ttgaccataa cgaacgtcaa
    25981 caaagtgtat cagatattaa cgatgttcgt gttttagaag ttattgacca tcatcgtatt
    26041 gcaaactttg aaacaactga tccgctttat tatcgtgctg aacctgttgg ttgtacagca
    26101 acaattctaa acaaacttta taaagaacac ggtgtggaaa ttaaaaaaga tacagctggc
    26161 ttaatgcttt cagctattat ctcagactct cttttattca aatcaccaac atgcactgaa
    26221 caagatgtaa aagcagcaaa agaacttgca tcaattgctg cagtagatgc agaagagtat
    26281 ggcttagcta tgcttaaagc tggagctgac ttaagcgaca aaacaattgc agaacttatc
    26341 acattagatg ctaaagaatt ccaaatgggt gagcatcgtg ttgaagtagc gcaaatcaat
    26401 gctgttgaca caaacgatgt tcttatccgt caagaagact tgaaacatgc tatgttagaa
    26461 acaatcgcag aaaaaggctt agatcttttt gttcttgttg taacagatat tcttaatagc
    26521 aactcaatgg cgcttgcaat cggtaaagaa acagaagctg ttgaaaaagc gtttgacgtt
    26581 tctcttgttg acgacaaagc tcttctaaaa ggtgttgtat ctcgtaagaa acaaatcgtt
    26641 ccaccactaa ctgaagcttt atcataataa aaatccttgg aggcctctcc aaggattttt
    26701 tctattaaac accttatttt ctcaccagtt aagtttctct ttgcagtgcc taataaataa
    26761 ctgaggattt tcctttacta agtaagaaaa cactcctttt gttgtatgta agtagagaaa
    26821 accatagctt tttgttgtaa tccgatacga gacatcaaga acagctttaa tagcaaactg
    26881 ctcccctcct gctacaattt tatcttcgta aagttcaagc tgatactcca actcctcata
    26941 ttcttgacga ttatgtttaa tcttttttgt aatatggata tatggatgtg aactaatcat
    27001 tctcttcctc ctcccttact atcattcccc tttccaacaa aaacacacag aagagagcac
    27061 accctaactc cttatagttt tctttttaat aaaaaggaag acctacagta agcattaaat
    27121 gatatttatg aatgcgtaaa attttaaact actctccttg gtttagtaaa aaaattcaca
    27181 aatattatct tgggcttttt aatttcctga aaacagctca taacataaaa gctaactaag
    27241 atttataaaa atgttcttct tataggtaac acaaaaaagc taggcattca atcatttgat
    27301 tcaatgtcta gctttttcta ttattatatc ttatacgtaa ccttcgctct tctccattgc
    27361 tcaaccgctc cacttccagc taaaacgcca aaaacaataa gcagaaatcc aataaattgt
    27421 gttatataaa gcgattctcc aagaaaaaga taagacgaaa ttaacgcaaa aaatggattt
    27481 aaattaataa atacggcaga ttcgcttgct ccaatgtgct gcattgcata attgtatgtc
    27541 atatgcccaa aagctgtggc aagaagtgcc gaacctataa aaacaagcca aattaaatag
    27601 tggtctgttt tcatcgtagc taatccttgt ggctcaacag caaggctaac aaagaataaa
    27661 ccagctgagc caacaatcat aagccatcct gtcataagac gggcatcaat atttgttgag
    27721 gcttttttaa taagcacaaa actgattgct tgggataccg cagctaaaaa gatttgcaca
    27781 tcaccgtacg atgtactaat tgctccgcca tgtcctgcta cgagagcaaa actcactcca
    27841 aaaaacgcaa aaagaattcc aactaccttc attatgctaa actttacttt taacaaaaat
    27901 agagatgcaa tagctgttaa gataggaaca aggcctagaa ttagtcctcc gttcatagcc
    27961 gttgtatttg ttagaccgac cgatagaaaa tagtggtgac caacaatatt gaacaaactc
    28021 acaacacaaa taaaactaaa ttctctaaat gtgagttttc gcaccactcc ttttacagaa
    28081 agaaaaagaa ggacagctac acctgctaca aaaatccgga aagcagtcat tgtgacaggc
    28141 gcaaattcat tcactaaaag cttgagccaa ataatattta atccccacat tgccattact
    28201 gctacaagaa gtgcatatac cgttgttttc ttcacttttt cacctgattt ccccttattc
    28261 acatatccaa tgtttattgt aactcctttc cagctttcct gaaagaatga atttgacgga
    28321 caaaataaaa agatggaaaa agacctagtc tttttccatc agtggccaat catataaaag
    28381 ttaatgataa aagcgataca aataatataa agaaacggat gaatttctct ataacgacct
    28441 gttaataatt ttagaaatgt ataagaaaga aaaccaaaag caagtccgtc cgcaatacta
    28501 aacgtaagag gcatcataac aattgttaaa aatgcgggaa taagctctgt gaaatcttcc
    28561 atattaatat ttttaatatc actaagcata agcgctccaa taataataag cggaggtgct
    28621 gttgcaacgg ttggaataaa ctgaataaga ggagctaaaa acagggtcag taaaaataaa
    28681 acagctactg ttaacgattt taatcctgtt cggccacctt ccgtaattcc tgtcgcattc
    28741 tcaatatatg tgttaagagc tgtacttcca aataaagcac ttgccatcgt accgatagag
    28801 tctgctgtta acgcccgatt taaattagga atctttccat tctcatcttc taatcctgct
    28861 ttacgcgaca gcccgatgag tgt
//
