LOCUS       NZ_JAICDG010000006     25353 bp    DNA     linear   CON 29-AUG-2024
DEFINITION  Actinomadura terrae strain OS3-83 contig6, whole genome shotgun
            sequence.
ACCESSION   NZ_JAICDG010000006
VERSION     NZ_JAICDG010000006.1
KEYWORDS    WGS; RefSeq.
SOURCE      Actinomadura terrae
  ORGANISM  Actinomadura terrae
            Bacteria; Actinomycetota; Actinomycetes; Streptosporangiales;
            Thermomonosporaceae; Actinomadura.
REFERENCE   1  (bases 1 to 470437)
  AUTHORS   Lee,S.D., Yang,H.L., Kim,I.S., Choe,H. and Kim,J.S.
  TITLE     Actinomadura terrae sp. nov. and Actinomadura litoris OS3-89,
            isolated from rhizosphere soil of cactus
  JOURNAL   Int J Syst Evol Microbiol 73 (1) (2023)
   PUBMED   36748505
REFERENCE   2  (bases 1 to 470437)
  AUTHORS   Lee,S.D.
  TITLE     Direct Submission
  JOURNAL   Submitted (15-FEB-2022) Institute of Jeju Microbial Resources, BioPS
            Co., Ltd., Sancheondan Dongil 16, Jeju 63243, South Korea
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: SPAdes v. 3.13.0
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 141x
            Sequencing Technology             :: Illumina
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_022751215.1-RS_2024_08_29
            Annotation Date                   :: 08/29/2024 06:12:19
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.8
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 8,085
            CDSs (total)                      :: 8,002
            Genes (coding)                    :: 7,936
            CDSs (with protein)               :: 7,936
            Genes (RNA)                       :: 83
            rRNAs                             :: 5, 4, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 3 (5S)
            partial rRNAs                     :: 2, 4, 4 (5S, 16S, 23S)
            tRNAs                             :: 67
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 66
            CDSs (without protein)            :: 66
            Pseudo Genes (ambiguous residues) :: 0 of 66
            Pseudo Genes (frameshifted)       :: 13 of 66
            Pseudo Genes (incomplete)         :: 56 of 66
            Pseudo Genes (internal stop)      :: 3 of 66
            Pseudo Genes (multiple problems)  :: 4 of 66
            CRISPR Arrays                     :: 4
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 21:31:58
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 174592
            Orig. end                         :: 199945
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            JAICDG010000006.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..25353
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="azole-containing-RiPP"
                     /product="thioamitides"
                     /region_number="1"
                     /rules="((YcaO or TIGR03604) and (((thio_amide and (PF06968
                     or PF04055 or PF07366)) or Lant_dehydr_C or Lant_dehydr_N
                     or (PF06968 or PF04055 or PF07366)) or (goadsporin_like or
                     PF00881 or TIGR03605)) or TIGR03882 or TIGR03603 or
                     thiostrepton or TIGR03602)"
                     /rules="((YcaO or TIGR03604) and TfuA)"
                     /tool="antismash"
     cand_cluster    1..25353
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="((YcaO or TIGR03604) and (((thio_amide
                     and (PF06968 or PF04055 or PF07366)) or Lant_dehydr_C or
                     Lant_dehydr_N or (PF06968 or PF04055 or PF07366)) or
                     (goadsporin_like or PF00881 or TIGR03605)) or TIGR03882 or
                     TIGR03603 or thiostrepton or TIGR03602)"
                     /detection_rules="((YcaO or TIGR03604) and TfuA)"
                     /kind="chemical_hybrid"
                     /product="azole-containing-RiPP"
                     /product="thioamitides"
                     /protoclusters="1"
                     /protoclusters="2"
                     /tool="antismash"
     protocluster    1..25353
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:15353](+)"
                     /cutoff="10000"
                     /detection_rule="((YcaO or TIGR03604) and (((thio_amide and
                     (PF06968 or PF04055 or PF07366)) or Lant_dehydr_C or
                     Lant_dehydr_N or (PF06968 or PF04055 or PF07366)) or
                     (goadsporin_like or PF00881 or TIGR03605)) or TIGR03882 or
                     TIGR03603 or thiostrepton or TIGR03602)"
                     /neighbourhood="10000"
                     /product="azole-containing-RiPP"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..15353
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="((YcaO or TIGR03604) and (((thio_amide and
                     (PF06968 or PF04055 or PF07366)) or Lant_dehydr_C or
                     Lant_dehydr_N or (PF06968 or PF04055 or PF07366)) or
                     (goadsporin_like or PF00881 or TIGR03605)) or TIGR03882 or
                     TIGR03603 or thiostrepton or TIGR03602)"
                     /neighbourhood="10000"
                     /product="azole-containing-RiPP"
                     /protocluster_number="1"
     misc_feature    complement(67..81)
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: weak, score: 17.79"
                     /tool="antismash"
     gene            complement(125..991)
                     /locus_tag="K2F47_RS32780"
     CDS             complement(125..991)
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1199: NmrA family
                     protein"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017622682.1"
                     /locus_tag="K2F47_RS32780"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="NAD(P)H-binding protein"
                     /protein_id="WP_242909913.1"
                     /transl_table=11
                     /translation="MTNSEKTSGNITTTPVESGLTLVLGGTGKTGRRVVERLEAMDVPV
                     RMGSRSAAPAFDWEDGSTWAPVLRGVERVYLVFYPDLAVPGAPEAIAAFTAAAVEAGVR
                     RVVLLSGRGEDEAQACERIVQESGLEWTIVRSSWFAQNFSEDYLLEPVQAGEVVLPAGE
                     VPEPFVHLDDVADVAVAALTGDGHHGEVYEVTGPRALTFGEAVAEIGRAAGREVAYVPV
                     STGDYAAALTEHGLPAEVVAFLTYLFSTVLDGRNTPTADGVRRALGREPRDFAEYAAET
                     AASGIWN"
     gene            1073..2035
                     /locus_tag="K2F47_RS32785"
     CDS             1073..2035
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1287: AraC family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012851728.1"
                     /locus_tag="K2F47_RS32785"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="AraC family transcriptional regulator"
                     /protein_id="WP_242909914.1"
                     /transl_table=11
                     /translation="MDALTDLLDGPRARGAFMLRCVLDPPWSVRIQDEAPLTLVAMVRD
                     DAWVIPDEGGPEHVHPGDVMIIRGPDPYTVADDPGTAPEIVIHPGQHCTTPDGTSLSEA
                     MDLGVRAWGNAPDGRTEMLIGTYQMRGAVTQRLLAALPALAVVRGDTWESPLVGLLGEE
                     IGRDEPGQEVVLDRLLDLLLIGTLRAWFSRPRAEKPGWYRAHGDAVVGPALRLLHDDLS
                     HPWTVADLAARVGVSRAALAQRFGKLVGEPPMAYLTGVRLAQAADLLRESDATLEAVAR
                     QVGYGNAFALSTAFKRERGVSPQEYRTSPEHRPAAAPAR"
     gene            complement(1974..2480)
                     /locus_tag="K2F47_RS32790"
     CDS             complement(1974..2480)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="K2F47_RS32790"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_242909915.1"
                     /transl_table=11
                     /translation="MTAVRERAPAGRGAPSRRVPSGFTVTVATVAAFVLLFYTVPNVEP
                     VWRAARGDGAPGAFTAARVSCVSHPGHEACSWYGTFTPADGGAARETTMYGAGRGDLAA
                     GERVPAIDVGRASRVYAPAGSHEWIPTGLVLLAGAALLYPLARRVSGRARRRDGAPARS
                     GTPAG"
     gene            complement(2477..3034)
                     /locus_tag="K2F47_RS32795"
     CDS             complement(2477..3034)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012893363.1"
                     /locus_tag="K2F47_RS32795"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="hypothetical protein"
                     /protein_id="WP_242909916.1"
                     /transl_table=11
                     /translation="MAAIAHRPTWMTRLNAGGHRAGLNVFFLIVLGHWAEHLVQAYQIW
                     VLGRPVPQSRGILGQWFPWLIKSEALHYGFAVVMLVAFILLRPGFSGRSRTWWNIALGI
                     QIWHHFEHLLLLVQAQSGHNIAGRAVPTSIIQLLVPRVELHLFYNAVVFAPMVVAMLLH
                     RRDAKAAGPGGAPSCDCALARA"
     protocluster    2756..25353
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[12755:15353](+)"
                     /cutoff="20000"
                     /detection_rule="((YcaO or TIGR03604) and TfuA)"
                     /neighbourhood="10000"
                     /product="thioamitides"
                     /protocluster_number="2"
                     /tool="antismash"
     proto_core      12756..15353
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="((YcaO or TIGR03604) and TfuA)"
                     /neighbourhood="10000"
                     /product="thioamitides"
                     /protocluster_number="2"
     misc_feature    complement(3350..3363)
                     /note="TFBS match to PerR, Peroxide regulator, confidence:
                     weak, score: 15.26"
                     /tool="antismash"
     misc_feature    3351..3364
                     /note="TFBS match to PerR, Peroxide regulator, confidence:
                     weak, score: 17.12"
                     /tool="antismash"
     misc_feature    3351..3366
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: weak, score: 16.99"
                     /tool="antismash"
     misc_feature    complement(3363..3379)
                     /note="TFBS match to GnfM, Regulator of nitrogen-fixation
                     genes, confidence: weak, score: 20.46"
                     /tool="antismash"
     gene            3422..5155
                     /locus_tag="K2F47_RS32800"
     CDS             3422..5155
                     /EC_number="7.-.-.-"
                     /GO_component="GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1288: ABC
                     transporter related protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020546052.1"
                     /locus_tag="K2F47_RS32800"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_242909917.1"
                     /transl_table=11
                     /translation="MLIRLLRAHIGPYKANVALLALLQLAATVANLYLPVVNAEIIDDG
                     VVRGDAGRVLELGLIMLAVSLAQMAGAIGAVFLGARTATAIGRDLRASVFRRVQGFSAR
                     ELGRFGAPSLITRTTGDVQQVQSLVLMTFTTMVAVPVMGLGGIVMALGLDVPLSGLLLA
                     VVPVLGLLVGLIVRRLRPLYRTTQRGVDGVNRMLRERIIGIRVVRAFVRDGHERERFGA
                     ANAELTDVALRAGRLMALTFPSVMLVVNASSVAVVWVGAHRVDTGDMRIGALTAFLAYL
                     TQILMSVMMATFMVMMVPRAEVCAERVQEVLDTASSVVPPRRPVGELREAGRLELRGAE
                     FRYPGAEARVLRGVDLAAGPGEVTAVIGSTGSGKSTLLGLVVRLFDATGGRVLVGGVDV
                     RDLDPALLSRTVGLVPQRPYLFSGTIAGNLRHGRPDATDAELWHALEVAQARDFVEALP
                     AGLSAPLSQGGTNVSGGQRQRLAIARTLVRAPDIYLFDDAFSALDPATDAALRASLARE
                     TAHATVVIVAQRVGTVRDADRIVVLDEGRVVGTGTHRELMAGNATYREIVLSQLTEQEA
                     G"
     gene            5152..7047
                     /locus_tag="K2F47_RS32805"
     CDS             5152..7047
                     /EC_number="7.-.-.-"
                     /GO_component="GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="resistance (resist) ABC_efflux"
                     /gene_functions="transport (smcogs) SMCOG1288: ABC
                     transporter related protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017621306.1"
                     /locus_tag="K2F47_RS32805"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_242909918.1"
                     /transl_table=11
                     /translation="MTGREAGRPMDLRRSGRRLARLTRPERALTGAVLLLTAGSVALTV
                     LGPLLLGRATDLVFAGVVGRHETEGASKAEVIGKLRERGDDGVADMLSGTDFTPGHGVD
                     FHAVGMTLLTVLGIYLLADVLGILQGRLATTVIQRTVSRLRSDVEAKLARLPLSYFDGR
                     PRGEILSRATGDVDNIGQTLQQTMGHMANALLTIVGVLAMMFWISPLLAVIALVTVPFS
                     VVVAARLGRRAQPRFVEQWRTTGTLNAYIEENYTGHAVVKSLGREAGAEAEFREHNDAL
                     FRASFRAQFLSGIIQPAMLFIGNINYVLVAVAGGLRVASGNLSIGDVQAFIQYSRQFTQ
                     PLDQAASMANLVQSGVASAERVFELLDAEEQEPDPARPERPAVVRGSVSLENVSFRYEP
                     DEPLIEDLSVKVEPGSTVAIVGPTGAGKTTLVNLLMRFYETTGGRILLDGTDIAAMSRD
                     DLRSRVGMVPQDAWLFGGTIADNIAYGRAGATRRQIEDAARAAHADRFVRTLPDGYDTV
                     VDDEGAGVSAGEKQLITIARAFLADPVILVLDEATSSVDTRTEILVRRAMATLSSGRTS
                     FVIAHRLSTIRDADVILVMEHGAIVEQGAHAELLEAGGAYARLYAAQFAAAPEID"
     gene            7144..7665
                     /locus_tag="K2F47_RS32810"
     CDS             7144..7665
                     /EC_number="2.3.1.-"
                     /GO_function="GO:0016747 - acyltransferase activity,
                     transferring groups other than amino-acyl groups [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF012792.5"
                     /locus_tag="K2F47_RS32810"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="WP_242909919.1"
                     /transl_table=11
                     /translation="MSTAPVALRSFGHEDLPAIRQTLLDVHAGAYADEKDEPSYQRFPW
                     LVDHWGGQPGFACVVGYDGDEPVGLAYGSPMPDGTEWWREHLAAPPADTSTFAVAELMV
                     VPRWRKTGTAARLHAALVEDRPEALAVLLVDSDRPRVEALYATWGYSRIGERPMPDSPG
                     SAVMLRRLRA"
     misc_feature    7718..7727
                     /note="TFBS match to ToxT, Regulator of MSHA biosynthesis,
                     confidence: weak, score: 13.55"
                     /tool="antismash"
     misc_feature    complement(7740..7755)
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: weak, score: 16.33"
                     /tool="antismash"
     misc_feature    complement(7864..7879)
                     /note="TFBS match to AfsQ1, Two-component system AfsQ1-Q2,
                     activator of antibiotic production, confidence: weak,
                     score: 16.94"
                     /tool="antismash"
     gene            7910..8161
                     /locus_tag="K2F47_RS32815"
     CDS             7910..8161
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="K2F47_RS32815"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_242909920.1"
                     /transl_table=11
                     /translation="MLEYTDSSQPVDGTIVAEAYEGVGSPLVQLRGSAAGTAADEAMRV
                     PETMSISLESIDVDVENQSYGMVAASTGCISNPGGPSC"
     gene            8295..9968
                     /locus_tag="K2F47_RS32820"
     CDS             8295..9968
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF019619.5"
                     /locus_tag="K2F47_RS32820"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="JmjC domain-containing protein"
                     /protein_id="WP_242909921.1"
                     /transl_table=11
                     /translation="MPLAGRLLTLTEFERLACGGGADLSLVQDGVARPVVADRADRVPG
                     RHVLAAYRSGTTLLLTRLATRSAPVAALCRGIELDLLEHGLLPSAPVTANAYLTPPRAQ
                     GFDRHHDDHSVLVVQLHGAKRWQVFEPGASEEAEPVVSTTLEAGDVLSIPRGFPHVAHT
                     TDEASLHLTLGVHTVSRADALADMLRTLEPFRRSVTGPDGLASTGLPELDAAAYLRDRR
                     LRWITGLDPLPGGRLVADAAAAAVGPDTVVRRVPLMPSESGTEGGLARLTFPGGTLRLD
                     GRLQPVLDHVAKAESFAPHHLPSVGAHYDAVELTRILVRHGIFQPVDAAVDEEPSAPAV
                     VQPVVQSAVRAERPAAPARSTRDLSLVRDSGPAVGHHLGWMRLRERLTGAECDDLVAAC
                     HEFPLSAPTTVDEAGHPAHRRADMRHVPHGPSTAWAYQLIEDVADEAARTVYGFDLTGI
                     KRAPQYVEYLPGNGHFHRHNDYSHDQLDSPRKITVIVQLSDPADYEGGALQMFGVETEE
                     LPRERGSVLVFPSMIDHRVTPVTRGMRRALVAWVAGPRLR"
     gene            10001..11569
                     /locus_tag="K2F47_RS32825"
     CDS             10001..11569
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     azole-containing-RiPP: PF04055"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PTHR43273"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_12"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) TIGR04085"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF015983.5"
                     /locus_tag="K2F47_RS32825"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="radical SAM/SPASM domain-containing protein"
                     /protein_id="WP_242909922.1"
                     /sec_met_domain="PTHR43273 (E-value: 8.6e-37, bitscore:
                     121.6, seeds: 35, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_12 (E-value: 3.4e-09, bitscore: 31.8,
                     seeds: 84, tool: rule-based-clusters)"
                     /sec_met_domain="PF04055 (E-value: 1.8e-22, bitscore: 75.2,
                     seeds: 518, tool: rule-based-clusters)"
                     /sec_met_domain="TIGR04085 (E-value: 2e-12, bitscore: 42.0,
                     seeds: 281, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSGKQTPLTLRAWQGGPVLAGPDEAPPPLPRFGAPDRAPFGAVGL
                     ADPAPPPAASEAAPEEDAAHRTGEGARAVYDLSTTEPVPFVSSLVHHRVDDDHLWIAVE
                     DGKLLVADDLDHELLTLLVAGTTPADAARELHRTRGLAPDAATRAMAKLVGRVALAGMI
                     RGIRGNHSIKKIRPHRFARFHLTNRCQLQCVHCYTSSSPFLPKDGELSTERWIRLVEDF
                     AANGGEKLLLTGGEALVHEGCIPVMRRAHELGLEVTLFSNGMAVPKHLDDLARYADIVQ
                     ISVDGPTAEIHDAIRGRHSFRRATRAIRLLLDAGVQTQVSTTIMMNNWAAIKAGLPAFI
                     DEWRDSDVKFRISYGAMAHGRGTDLDHDLNEDEVRDWVDELLGGLRIGDDKAHGPNKVQ
                     KINSCGYAEQLVVASDGIVYPCHLLSGALGHIDQLPLSEITDYLKRTSDAFTVDNRKGC
                     QSCDLRNLCGGTCRVEDEKHTGSRLITTCTPEEKLRRRRFLVRRYRPVPGAAPEVGSEV
                     GPGSS"
     gene            11566..12759
                     /locus_tag="K2F47_RS32830"
     CDS             11566..12759
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF019619.5"
                     /locus_tag="K2F47_RS32830"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="cupin domain-containing protein"
                     /protein_id="WP_242909923.1"
                     /transl_table=11
                     /translation="MTLADLLRPRAVADFLDTEWTREPCVFPGAAKGAALLDLDGFEAM
                     LGGLHYAHEGLLHLAHGDRRRLPATFMDADGMLDLRQVRKAFKGGETLYLTKAHRLSPV
                     LADLCRGVELDLADHGVVLRKPAGAHVFATPPSAQGFAPHRDEHGSLVVQTEGRKAWMV
                     EERPGPPRPGAISPQEWAKIRFREFALEPGDVLYVPEYCGHAARTEEAHSLHVTLRLFP
                     LRWRDVLDEVVGALPALNAFVPAARTHDPAALATGLAELLRSPDVGAALPGLLAGLAAR
                     RTERRAVLPDGGLGGPDGIDENTWLVRARGADCHVTSGDDAATIHFPGGAVRGPIGVLA
                     AFEHIAKARVLRAADLPGALDPDASLGVVRKLVADGLLRRARPGETAETGEFGEFAR"
     gene            12756..15353
                     /locus_tag="K2F47_RS32835"
     CDS             12756..15353
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     azole-containing-RiPP: YcaO"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     thioamitides: TfuA"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     thioamitides: YcaO"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:TIGR00702.1"
                     /locus_tag="K2F47_RS32835"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="YcaO-like family protein"
                     /protein_id="WP_242909925.1"
                     /sec_met_domain="TfuA (E-value: 2e-34, bitscore: 112.6,
                     seeds: 78, tool: rule-based-clusters)"
                     /sec_met_domain="YcaO (E-value: 1.1e-63, bitscore: 210.6,
                     seeds: 127, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRARPIVFLGPSMPLAEARPILDADYRRPVRRGDLDAIPAGAVVG
                     IIDGVFEQTLSVSPTEVRAAVDRGVVVYGGGSMGALRAAEVPAVTGVGLVYAWYRDGTV
                     TRDDEVALLFDEETGAPLTVPAVNVRYAVERLHRTGTIDASTADRLLTTALELPFKART
                     YRHIVHRAGLLGRADGADLVAMLASHDLKHRDAQSVLEAIGAARPVSRKGAAPRPTAAT
                     PVPEPITTGTALIWESGDRVGDEELFAFLAYTGRLEPWARSAHPVPSEFVRPVDAPAAQ
                     ALFGTAVRRWGWLSSEEARVTLADLGMDMPTLNRRAEAEAVAEAGLTAWAKADPQAFRR
                     SLRAALFLHDASLKREVMRLGGLNLFAERDPRPASTEELSDAWQVLCKANLAFDIEAVR
                     QRWAQWGYGDRAAQDAFVHRLARARRAGGELAATMAGRAAPAAGPVPHPDLPLRARPKP
                     PDERRFCLPMAEARDHATRLAKTIGITRIGMVGDLGDLGGVQIAQAARPDGCWSSTYGS
                     GKSLSEDGAHVGSVMEELEKWAQEQWVPRAADLVQAPYRDVAGDAVDPAALALPYDSSY
                     APDRPLTWTRCPDVLSGRTVLVPLDLLRMERGPRDICFSPRGARKVIATNGLGSGFSRE
                     EALLHGLCEYVERHAQRLAEIALVNPGGTGAPPFRFVDLDTVPDRAREVAERLRRVGLT
                     VRVLDITADVRIPTFMATVWRDLNRSEGYGTHPDPGTAVEMAVLEAAQSIACAVAGGRE
                     DLTIQARSLGRHERPRPVAREDAWFWLDPDVAPAPMTQGLTGDDVLDDLWWALGRVADA
                     GLPHVPVLDLTHPEIDPAHVVRVIVPGLESNNPFATGERARLSLLRDLLPRWS"
     gene            15372..16124
                     /locus_tag="K2F47_RS32840"
     CDS             15372..16124
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PhyH"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF017532.5"
                     /locus_tag="K2F47_RS32840"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="phytanoyl-CoA dioxygenase family protein"
                     /protein_id="WP_242909927.1"
                     /sec_met_domain="PhyH (E-value: 3.6e-26, bitscore: 87.4,
                     seeds: 39, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTTTELDLRQVDSTVRTIGEHGYVLLENLLPAPTIDRMREALERL
                     LHEEKARNLHPSGHQRVLHVLVKDPVFVDALVHPLVLAVWRRYLSEDLICSTFTANSLW
                     PGATEQYWHADHPYWTLTPPWPSIPLSGQCIWFLDDFTDENGATAGIPGSHRADRLPDM
                     GESWCDEGEILAGPAGSAIFADGAWWHTSRPNRTTALRSALLVTYTHTFCVPQEDMRGQ
                     LDALSNPSDLVVELLGGKQYQPRRDFPY"
     gene            complement(16294..17229)
                     /locus_tag="K2F47_RS32845"
     CDS             complement(16294..17229)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="K2F47_RS32845"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_242909929.1"
                     /transl_table=11
                     /translation="MRDTTPPRDDDPAAEDPAGDGQEVSGSRVGGSLFQIRDVRGNITI
                     GNAPPGHRPSPTRRWTWAAAVAATSILAAGGVWILHGRPQRAPRPAPSQSPLSVTRSVT
                     PIQRIRAVQGDQAFIFSKPAAALPSLPPGYRNDQQLVEKWGYGNGGVDADITTLELVIQ
                     GTSAKSVVLTDFRIDVLGRAAPPRATYVKVFPGGDGVDGRNATDLDEAAPMIKDLRNVS
                     GEDTGGTWSFPLRVSQAEPEVLYLWAGASKHDCWWTAKLHFVADGKPGFVVINNKGRPF
                     RTASSANSKRYAVEDGRVVPGGGPLGGPAD"
     misc_feature    complement(16492..16494)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     misc_feature    17228..17242
                     /note="TFBS match to MexT, Global virulence regulator,
                     confidence: weak, score: 16.64"
                     /tool="antismash"
     misc_feature    complement(17929..17939)
                     /note="TFBS match to HypR, L-hydroxyproline utilization
                     repressor, confidence: weak, score: 18.94"
                     /tool="antismash"
     gene            18035..18265
                     /locus_tag="K2F47_RS32850"
     CDS             18035..18265
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="K2F47_RS32850"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_242909931.1"
                     /transl_table=11
                     /translation="MIGTVAGNQTINIPSTFNDRTSSIWTPPSSRTGCTRLTLWSNSNG
                     HGDAWIHEFNDGGAANVPTWMNDRASSLTVE"
     misc_feature    18640..18653
                     /note="TFBS match to BldD, Development and antibiotic
                     global regulator, confidence: weak, score: 19.2"
                     /tool="antismash"
     gene            18762..19229
                     /locus_tag="K2F47_RS32855"
     CDS             18762..19229
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="K2F47_RS32855"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_242909932.1"
                     /transl_table=11
                     /translation="MDATTEHGDTLGYPWTLRVRIQHGQLLARLHLTTIERESLLHCDL
                     PCDAVCVHVGLSATGPVRVLVAAPPSAEAMRVRTVGGRLTPLAVRHPAGAPVAIGAALL
                     ERDDPPVRLHVLDASGGDHAEPLDDPRLGPAARPHRTLLRRRGPRQFRLAG"
     gene            complement(19226..19888)
                     /locus_tag="K2F47_RS32860"
     CDS             complement(19226..19888)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="K2F47_RS32860"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_242909934.1"
                     /transl_table=11
                     /translation="MTFVFTTGRAPAGAAACAALAASALLTACDGNGGGAPHREGPATV
                     TRLEFTETSYSGGEGREGAVTTVRIWVSLRGRQAMTIHSLTSRPGGVKVYESRWDRSLP
                     QAFAVRDWATCEEGVEDPPEPRLDTLDALLDDVLGPPARPSGARPVKGRPNAWETVRGL
                     RTLRIVQHGAAYSDREVLTFNESGRLVGRISSVGVAQDARMPGWAAGWTRCAPSVTG"
     misc_feature    complement(19873..19887)
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: weak, score: 16.73"
                     /tool="antismash"
     gene            complement(19965..20441)
                     /locus_tag="K2F47_RS32865"
     CDS             complement(19965..20441)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="K2F47_RS32865"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_242909936.1"
                     /transl_table=11
                     /translation="MRLKTATLALGTSAFALASVVALGGQANADVRASAQPAAARFQTQ
                     QTQPDHRVRVLPGWYLTPLAYKSGKYAKGQAIAHGPYNVARVDVWTDLARKRFYGWQQL
                     DTDHSGGRNTRRVASVSRKKCGGTYTYRVRARATAVHKGKTYRAAASDQRRFRC"
     misc_feature    complement(20373..20375)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     misc_feature    20792..20803
                     /note="TFBS match to CcpA, Catabolite control protein A,
                     confidence: weak, score: 16.14"
                     /tool="antismash"
     gene            complement(21417..22742)
                     /locus_tag="K2F47_RS32870"
     CDS             complement(21417..22742)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017592947.1"
                     /locus_tag="K2F47_RS32870"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="hypothetical protein"
                     /protein_id="WP_242909937.1"
                     /transl_table=11
                     /translation="MKRFVRGALALAFPLVMPMTLAGAAHAGAAPPTLAGWRLLDAESF
                     DRRLDDAKVPWRSDGDGPASPYNVDMYDNDGAFFDTVGGPAFQTQLTKMSTYRKSFTFG
                     EHGWLTAELAARDADGDGRPDAPPTLTSRGGVARLDEPSHQAGVVIRSTRALPAEYRVE
                     MTLRGLDFGGQRNGSWDYPDGRINGYSPQGCKTNFPWASGGDFSRPECQWADVRTDSNG
                     FYYMSIMDYGRVAPHNNVFVHGHRKVAMDGYNRYKYTGAGLRYCNPATGQYEPYTAGTG
                     NGVNAIFMTDDRRYPTMPGTEYLMESQCGLAKGGAIVSTIDLKPELLPKEPYRFAVERR
                     NGAYTMEMSGNFAHVGKATFRYTRSFVQDGEPIWHYNQKPSEYDGRYNADWTWKGPGGT
                     LVDRDTWPAGSAYPDHFMIGDPHMNFYEGSARVDDVRLYTPK"
     misc_feature    complement(22853..22868)
                     /note="TFBS match to DasR, N-acetylglucosamine dependent
                     repressor, confidence: weak, score: 20.48"
                     /tool="antismash"
     gene            22929..23660
                     /locus_tag="K2F47_RS32875"
     CDS             22929..23660
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1136: GntR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017589605.1"
                     /locus_tag="K2F47_RS32875"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="GntR family transcriptional regulator"
                     /protein_id="WP_242909938.1"
                     /transl_table=11
                     /translation="MRSAGEARNGNTKRQAVRRRLLEMLDGLDVGDALPSERRLAADLG
                     VSRPTLRQAIDGLVAEGLLHRRHGSGTYVSEPRIAVSLTMTSFTEDMIRRGMRPGGRVL
                     SFRTEAAGARIGRRLAVSPLEEVFTIRRLRLADEATMAIETLYMPRALMPGLRRQDLEG
                     RSFYELLRGSGVEIASGTETIEPTVTTEDEAAELGVPVHMPAFLFERVTRDAGGRPLEY
                     VRSLYRGDRYRLELDLRPPSH"
     gene            23762..25195
                     /locus_tag="K2F47_RS32880"
     CDS             23762..25195
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017592932.1"
                     /locus_tag="K2F47_RS32880"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="PTS ascorbate transporter subunit IIC"
                     /protein_id="WP_242909939.1"
                     /transl_table=11
                     /translation="MDVIKDILTFLADNVFGQVPILIGLITLIGLLLQRKRFEDVFAGA
                     LRSTIGVVILFIGVDVFTGGLTSFQTVLASAMGTTPPKADHSLTQFLTDQGGTIALVIT
                     VAFLVHVLVVRLFPAARYLYLTGHLMFWVSTVTVASLVTIAPGQDQLTLVLCGAGFVAA
                     YWTVQPLWMRPLMRRVMPDDRFGYAHTSSLTCLITGYAARPLGSREKHDTEKLKLPRQL
                     SFFKDVNVSTALIISVIMLVAVAFADNAVVGKAAAEMDPKLSSWVWALLVGLRFAGGIA
                     ILLFGVRMFLGEIVPAFKGFSDKVIPGTRPALDAPTVFPVAPTAVMLGFVVSTGVFLVC
                     LAVFAGAGWFTLAPPMIMLFFVGGAAGLFGNVVAGWRGAVLGGVISGLVLAIGQSVTWG
                     LYERTAPELATLADPDWYAIGWLLKAVDPVVGDGSIWLVPAVALAAMTATLLVLGRAEK
                     RRAVAEDAGSGDDKAIVNA"
ORIGIN
        1 agaagacgaa gaacgcgccg gccatccccg aggccatcag gatcgacagg gccgccgagg
       61 ccgccgtgag agagaatttc atgattgctc cgttagtccg tttcggtggt tcaggtccgg
      121 tggttcagtt ccagatgccg ctggcggcgg tctcggcggc gtactcggcg aagtcccggg
      181 gttcgcggcc gagggcccgc cgcacgccat cggcggtggg ggtgttacgg ccgtccagaa
      241 ccgtcgagaa aagataggtc agaaaggcga ccacctcggc cgggaggccg tgctcggtga
      301 gcgcggcggc gtagtccccg gtgctcaccg gcacgtaggc gacctcgcgc ccggccgcgc
      361 ggccgatctc ggcgacggcc tcgccgaagg tgagcgcccg ggggcccgtc acctcgtaga
      421 cctcgccgtg gtgcccgtcc ccggtgagcg ccgcgaccgc cacgtcggcg acgtcgtcca
      481 ggtggacgaa cggctcgggc acctcgcccg cgggcagcac gacctcgccc gcctggaccg
      541 gctccagcag gtagtcctcg ctgaagttct gcgcgaacca gctggaccgg acgatcgtcc
      601 actccaggcc cgactcctgg acgatccgct cgcaggcctg cgcctcgtcc tcgccccggc
      661 cggagagcag gaccacccgc cggaccccgg cctccaccgc cgccgccgtg aacgcggcga
      721 tcgcctccgg cgcgccgggg accgcgaggt cggggtagaa gacgaggtag acgcgctcga
      781 cgccgcgcag gacgggcgcc caggtggagc cgtcctccca gtcgaaggcc ggggccgccg
      841 accgggaccc catccgcacc gggacgtcca tggcctccag ccgctcgacg acgcgccgcc
      901 cggtcttgcc ggtgccgccg aggacgagcg tcaggccgct ctcgacaggg gtggtggtga
      961 tgtttccgct ggtcttctcg ctgttcgtca tggctatgag tcaaccgggg cgcggcctcc
     1021 gggaacatcg tcgagaagct cgtccgcata cgcgagcgtc tacgctggcg tcatggacgc
     1081 cctgaccgat ctgctcgacg gcccccgcgc acgcggcgcg ttcatgctgc gctgcgtgct
     1141 cgacccgccg tggtcggtgc ggatccagga cgaggcgccg ctgacgctgg tcgcgatggt
     1201 ccgcgacgac gcgtgggtga tccccgacga gggcgggccc gagcacgtcc accccggcga
     1261 cgtgatgatc atccgcgggc cggacccgta caccgtcgcc gacgaccccg gcaccgcgcc
     1321 ggagatcgtg atccacccgg ggcagcactg caccaccccg gacggcacga gcctgtcgga
     1381 ggcgatggac ctcggcgtgc gggcctgggg caacgcgccc gacggccgga cggagatgct
     1441 gatcggcacc taccagatgc gcggcgcggt cacccagcgg ctgctggcgg cgctcccggc
     1501 gctcgcggtc gtgcggggcg acacgtggga gtcgccgctg gtcggtctgc tcggcgagga
     1561 gatcggcagg gacgagccgg gccaggaggt ggtcctcgac cggctgctgg acctgctgct
     1621 catcgggacg ctgcgcgcgt ggttctcacg gccgcgcgcc gagaagcccg gctggtaccg
     1681 ggcgcacggc gacgcggtgg tcggcccggc cctgcggctg ctgcacgacg acctctcgca
     1741 cccgtggacg gtcgcggacc tcgccgcccg cgtcggggtc tcccgggcgg cgctcgcgca
     1801 gcggttcggg aagctggtgg gcgagccgcc gatggcgtac ctgaccggcg tccgcctcgc
     1861 ccaggcggcc gacctgctgc gcgagagcga cgcgacgctg gaggcggtgg cgcggcaggt
     1921 cggctacggc aacgcgttcg cgctcagcac cgcgttcaag cgcgagcgcg gcgtcagccc
     1981 gcaggagtac cggacctcgc cggagcaccg tcccgccgcc gcgcccgccc gctgacccgg
     2041 cgggcgagcg ggtagagcag ggcggcaccg gccagcagga cgagcccggt cgggatccac
     2101 tcgtgcgacc cggccggcgc gtacacgcgg ctcgcgcgcc cgacgtcgat cgcgggcacc
     2161 cgctcccccg ccgcgaggtc gccgcgcccg gcaccgtaca tcgtcgtctc ccgcgccgcg
     2221 ccgccgtccg cgggcgtgaa cgtgccgtac caggagcacg cctcgtgccc ggggtggctg
     2281 acgcacgaca cgcgcgcggc ggtgaacgcg cccggcgcgc cgtcgccgcg cgccgcccgc
     2341 cagaccggct ctacgttcgg gaccgtgtag aacagcagga cgaacgcggc gacggtcgcg
     2401 accgtgacgg tgaacccgga cgggacgcgg cgggacggtg cgccgcgtcc cgccggggcc
     2461 cgttcccgga cggccgtcat gcgcgggcga gcgcgcagtc gcaggagggg gcgccgcccg
     2521 ggccggccgc cttcgcgtcc cgccggtgca gcagcatggc gaccaccatc ggggcgaaca
     2581 cgaccgcgtt gtagaacagg tgcagctcca cgcgcgggac cagcagctgg atgatgctcg
     2641 tcggcacggc acggccggcg atgttatggc cgctctgcgc ctggacgagc aggagcaggt
     2701 gctcgaagtg gtgccagatc tggatgccga gggcgatgtt ccaccacgtc cgcgaccgtc
     2761 cggagaagcc ggggcgcaac aggatgaacg ccaccagcat caccaccgcg aagccgtagt
     2821 ggagcgcctc ggacttgatc agccacggga accactgccc gaggatgccg cgcgactgcg
     2881 ggacgggccg gccgagcacc cagatctggt acgcctgcac gaggtgctca gcccagtggc
     2941 cgaggacgat caggaagaac acgttgaggc cggcccggtg accgcccgcg ttgaggcggg
     3001 tcatccaagt gggccggtgg gcgatggcgg ccatgggcta ctcctcgctg ccgcggcgac
     3061 gcggcgggga ccgcgatctt tgtgtaacgc cgttatggct tcattctggg gcaccgcgcg
     3121 caccgcgtca cgccgacggc cggatccggc ctgatggacg tccggaatca ccgcgcttgc
     3181 gccgtcctgg cacgccgaca gcccgcgctg gcggcgtccg cccgtgcgat ccagggtttt
     3241 cagtcagctc acgccttcca gccgccacgg cgacccgcgc tatttcggaa actgtcggca
     3301 ctggccgaga aggcactgaa ctcttccacc aacccccatg aatccacttg tatgatcatt
     3361 attgcccgcc tttaaagctc gcccaaaacg gtgcgataca tccaatatcg agagtgcgtg
     3421 tgtgctgatc cgacttctgc gggcccatat cgggccgtac aaggcgaatg tcgcgctgct
     3481 ggcgctgctg caactggccg cgaccgtcgc gaacctctat ctgccggtgg tgaacgccga
     3541 gatcatcgac gacggggtgg tcagggggga cgccggccgg gtcctggaac tgggcttgat
     3601 catgctcgcg gtgtcgctgg cgcagatggc cggggcgatc ggggcggtgt tcctcggcgc
     3661 gcggaccgcg acggcgatcg gccgcgacct ccgcgcctcg gtcttccggc gggtccaggg
     3721 cttctcggcg cgggagctgg ggcggttcgg ggcgccgtcg ctgatcaccc ggaccaccgg
     3781 cgacgtccag caggtgcagt cgctggtgct gatgacgttc acgaccatgg tcgcggtgcc
     3841 ggtcatgggc ctgggcggga tcgtcatggc gctcgggctg gacgtgccgc tgtccggcct
     3901 gctgctggcg gtcgtcccgg tgctggggct gctggtcggc ctgatcgtcc gccggttgcg
     3961 cccgctctac cgcaccacgc agcggggggt ggacggcgtg aaccgcatgc tgcgcgagcg
     4021 gatcatcggc atccgggtcg tccgcgcgtt cgtccgggac gggcacgagc gcgagcgctt
     4081 cggcgcggcc aacgcggagc tgaccgacgt cgcgctgcgg gcgggccggc tgatggcgct
     4141 gacgttcccg tccgtgatgc tggtggtgaa cgcctccagc gtggcggtcg tgtgggtcgg
     4201 cgcgcaccgc gtcgacaccg gggacatgcg gatcggggcc ctcaccgcgt tcctcgccta
     4261 cctgacgcag atcctcatgt cggtgatgat ggcgacgttc atggtcatga tggtgccgcg
     4321 cgcggaggtc tgcgccgagc gcgtccagga ggtgctcgac accgcgtcca gcgtcgtccc
     4381 gccgaggcgg ccggtcgggg agctgcgcga ggccgggcgg ctggagctgc gcggcgccga
     4441 gttccgctat ccgggcgccg aggcgagggt gctgcggggc gtcgacctcg cggccgggcc
     4501 cggcgaggtg acagcggtga tcggctcgac gggcagcggg aagtcgacgc tgctcgggct
     4561 cgtcgtccgg ctgttcgacg ccaccggcgg ccgcgtgctg gtcggcgggg tggacgtccg
     4621 ggacctcgat ccggcgctgc tctcccggac ggtggggctg gtgccgcagc gcccgtacct
     4681 gttctccggg acgatcgcgg gcaacctgcg ccacggccgt ccggacgcca ccgacgccga
     4741 gctgtggcac gcgttggagg tcgcccaggc cagggacttc gtcgaggcgc tgcccgcggg
     4801 gctctccgcc ccgctctcgc agggcggcac caacgtgtcg ggcggacagc ggcagcggtt
     4861 ggcgatcgcg cggacgctcg tgcgcgcccc ggacatctac ctgttcgacg acgcgttctc
     4921 ggcgctcgac cccgcgacgg acgcggcgct ccgcgcgtcc ctggcccgcg agaccgcgca
     4981 cgcgaccgtc gtgatcgtcg cccagcgggt cgggaccgtc cgggacgcgg accggatcgt
     5041 cgtgctggac gagggacgcg tcgtgggcac cggcacccac cgcgagctca tggcgggcaa
     5101 cgccacgtac cgggagatcg tcctgtccca gctcaccgag caggaggccg ggtgaccggg
     5161 cgagaggccg gaaggccgat ggacctccgc cgctcgggac gccggttggc gcggctgacg
     5221 cggcccgagc gcgcgctgac gggcgcggtg ctgctgctca cggccgggag cgtcgcgctt
     5281 accgtcctcg ggccgctgct cctcggccgc gccaccgacc tggtcttcgc cggggtggtc
     5341 ggacgccatg agaccgaggg cgcgagcaag gccgaggtca tcgggaaact gcgggaacgc
     5401 ggtgacgacg gcgtcgcgga catgctctcg gggaccgact tcacccccgg ccacggcgtc
     5461 gacttccacg ccgtcggaat gacgctgctg accgtcctcg gcatttatct gctggccgac
     5521 gtcctcggca tcctccaggg ccggctggcc accaccgtga tccagcggac ggtgtcgcgc
     5581 ctgcgatccg acgtcgaggc caaactcgcg cggctgcccc tctcctattt cgacggacgg
     5641 ccgcgcgggg agatcctcag ccgcgccacg ggcgacgtcg acaacatcgg ccagacgctc
     5701 cagcagacga tgggccacat ggccaacgcg ctgctcacga tcgtcggcgt gctcgcgatg
     5761 atgttctgga tatcgccgct cctggccgtg atcgcgctgg tcaccgtgcc gttctcggtc
     5821 gtcgtcgcgg cccgcctcgg ccggcgcgcg cagccgcggt tcgtcgagca gtggcggacg
     5881 accggcacgc tcaacgccta catcgaggag aactacaccg ggcacgccgt ggtgaaatca
     5941 ctcggccgcg aggccggggc cgaagcggag ttccgagagc acaacgacgc ccttttccgt
     6001 gcctctttcc gcgcgcagtt cctctccggg atcatccagc ccgcgatgct tttcatcggc
     6061 aacatcaatt acgtgctggt cgcggtcgcc ggagggttgc gcgtggcgtc cggaaacctg
     6121 tcgatcggtg acgtgcaggc gttcatccag tactcgcggc agttcaccca gccgctcgac
     6181 caggcggcga gcatggcgaa cctggtgcag tcgggcgtcg cgtccgccga gcgggtcttc
     6241 gagctgctgg acgcggagga gcaggagccc gacccggcgc gtccggaacg tccggcggtg
     6301 gtgcgggggt cggtgtcgct ggagaacgtc tcgttccggt acgagccgga cgagccgctg
     6361 atcgaggacc tgtcggtgaa ggtggagccc ggcagcacgg tcgcgatcgt cgggccgacg
     6421 ggcgcgggca agaccacgct ggtcaacctg ctgatgcgct tctacgagac gacgggcggg
     6481 cggatcctgc tcgacggcac cgacatcgcc gcgatgtccc gcgacgacct gcgctcccgc
     6541 gtcggcatgg tgccgcagga cgcctggctg ttcggcggca cgatcgccga caacatcgcc
     6601 tacggccgcg cgggcgcgac ccgccggcag atcgaggacg ccgcccgcgc cgcgcacgcc
     6661 gaccgcttcg tccggaccct gccggacggg tacgacacgg tcgtcgacga cgagggcgcc
     6721 ggtgtcagcg ccggcgagaa acagctgatc acgatcgcgc gggcgttcct cgccgacccg
     6781 gtgatcctcg tcctggacga ggcgacgagc tcggtcgaca cccgcaccga gatcctcgtc
     6841 cggcgcgcga tggccaccct gagcagcggc cggacgagct tcgtcatcgc gcaccggctc
     6901 tccacgatca gggacgccga cgtgatcctc gtgatggagc acggcgcgat cgtcgaacag
     6961 ggcgcgcacg ccgaactcct ggaggccgga ggcgcctacg cgcgcctgta cgcggcgcag
     7021 ttcgccgccg cccccgaaat cgactgagga aatggggcgc gacggcgact accggccgcg
     7081 acctgatcac tcgcacactt ggaaaacagc gccggaccgc cctccgatcg aatggagcag
     7141 cccttgagca ccgcccccgt cgcccttcgc agtttcggac acgaggacct ccccgccatc
     7201 cggcagacgc tcctggacgt gcacgccggc gcctacgcgg acgagaagga cgagccgtcc
     7261 taccagcgct tcccctggct cgtcgaccac tggggcgggc agcccgggtt cgcgtgcgtc
     7321 gtcggctacg acggcgacga gccggtcggc ctcgcctacg ggtcgccgat gccggacggc
     7381 accgagtggt ggcgggagca cctggccgcg ccgccggcgg acacctcgac cttcgccgtc
     7441 gccgagttga tggtggtccc gcgctggcgg aagaccggca ccgccgcgcg gctccacgcg
     7501 gcgctggtcg aggaccggcc cgaggccctg gccgtgctcc tggtcgactc cgaccgcccg
     7561 agggtcgagg ccctgtacgc gacgtggggc tattcccgga tcggcgagcg gccgatgccg
     7621 gactcgcccg gctccgcggt catgctccgg cggctgcgcg cctgaggccg gagtgataac
     7681 cggggcggtt gataccgcga tctcttttcg gccactccat tttctgattc ggtcattccg
     7741 aagatcatga tcgatggtcc gagttccagt aggaaaatcg aacccgccgt cagggaaatt
     7801 tggtcgacag gagatcttgc aaacgttcca tcggcgagtc agactcaaaa gcgcgttcag
     7861 tgcgtgaccg aacggtcacc gatccagcct gatcagtgag gagcgcgcct tgcttgagta
     7921 caccgactcg tcgcagccgg tcgacggaac gatcgtggca gaagcgtacg agggcgtcgg
     7981 cagcccgctc gtgcagttga ggggctccgc cgccgggacc gccgccgacg aggcgatgcg
     8041 ggttccggag accatgtcga tctccctgga gagcatcgac gtcgacgtgg agaaccagag
     8101 ctacggaatg gtcgccgcga gcaccggatg catctccaac cccggtgggc cgagttgctg
     8161 aaccccgcgg ttcggagttg atcctcgtgg acaccgacgg ttggggactg tccgcggttc
     8221 tcggtgatcg ggacgtcccg accttcttcc gaacgagctg ggaacgggag gcattgtcgc
     8281 tccgcggggc ggcaatgccg ctcgccggcc ggctgctcac gctcaccgag ttcgagcggc
     8341 tggcctgcgg cggcggcgcc gacctgagcc tcgtccagga cggcgtggcg cggccggtcg
     8401 tcgccgaccg cgccgaccgg gttccgggac ggcacgtcct ggccgcctac cggtccggca
     8461 cgacgctgct gctcacccgc ctggccaccc gcagcgcccc ggtcgcggcg ctgtgccggg
     8521 gcatcgagct cgacctgctc gaacacggcc tgctcccctc cgcccccgtg accgccaacg
     8581 cctacctcac gccgccgcgg gcccagggct tcgaccggca ccacgacgac cactcggtgc
     8641 tcgtcgtcca gctgcacggc gccaaacggt ggcaggtgtt cgagccgggc gcctcggagg
     8701 aggcggaacc ggtcgtctcc accaccctgg aggccggcga cgtcctgtcg atcccgcgag
     8761 gcttccccca cgtcgcgcac accaccgacg aggcgtcgct ccacctgacg ctcggcgtgc
     8821 acaccgtctc gcgggcggac gccctggcgg acatgctgcg gacgctcgaa cccttccgcc
     8881 gctcggtcac cgggcccgac ggcctcgcct ccaccggcct gccggagctg gacgccgccg
     8941 cctacctgcg cgaccgcagg ctccgctgga tcaccgggct cgaccccctg cccggcgggc
     9001 ggctggtcgc ggacgcggcc gccgccgcgg tcgggccgga cacggtcgtc cggcgggtgc
     9061 cgctgatgcc gagcgagtcg ggcaccgagg gcggcctcgc gcggctgacc ttccccggcg
     9121 gcacgctgcg cctggacggg cggctccaac ccgtcctcga ccacgtggcg aaggccgagt
     9181 ccttcgcccc ccaccacctg ccgtcggtcg gcgcgcacta cgacgccgtc gagctgaccc
     9241 gcatcctggt cagacacggc atcttccagc cggtggacgc ggcggtcgac gaggagccgt
     9301 cggcgcccgc cgtcgtccag cccgtcgtcc agtccgccgt ccgggccgag cggccggcgg
     9361 ccccggcgcg gtccacgcgc gacctgtcct tggtacgtga cagcggcccg gcggtcggcc
     9421 accacctcgg ctggatgcgg ctgcgggagc ggctcaccgg cgccgaatgc gacgacctcg
     9481 tcgccgcgtg ccacgagttc ccgctgtcgg cgccgaccac ggtggacgag gcgggccacc
     9541 ccgcccaccg gcgcgcggac atgcggcacg tcccgcacgg gccgagcacg gcgtgggcgt
     9601 accagctgat cgaggacgtg gccgacgagg cggcgcggac cgtctacggc ttcgacctca
     9661 cgggcatcaa gcgcgccccg cagtacgtcg agtacctccc cggcaacggg cacttccacc
     9721 ggcacaacga ctacagccac gaccagctcg actccccccg caagatcacg gtgatcgtcc
     9781 agctgtccga cccggccgac tacgagggcg gggcgctcca gatgttcggc gtcgagaccg
     9841 aggagctgcc gcgcgagcgg ggctcggtcc tggtcttccc gtcgatgatc gaccaccgtg
     9901 tcacgcccgt gacgcggggc atgcgccgcg cgctcgtggc gtgggtcgcg gggccccggc
     9961 tgcgctgatc acgatccccg tccgacctga gaggaatgcg atgagcggca aacagacccc
    10021 gctgaccctg cgcgcctggc agggcgggcc ggtgctcgcc gggcccgacg aagccccgcc
    10081 gccgctcccc cggttcgggg cgccggaccg ggccccgttc ggcgccgtcg gcctggcgga
    10141 ccccgcgccg ccgcccgccg cgtccgaggc cgcgcccgag gaggacgccg cgcaccggac
    10201 gggtgagggt gcccgcgccg tctacgacct gtccacgacg gagcccgtcc cgttcgtctc
    10261 ctcgctcgtc caccaccgcg tcgacgacga ccacctctgg atcgccgtcg aggacgggaa
    10321 gctgctggtc gccgacgacc tcgaccacga gctgctgacc ctcctcgtcg cgggcacgac
    10381 gcccgccgac gcggcccggg agctgcaccg cacccgcggc ctcgccccgg acgcggcgac
    10441 gcgggcgatg gccaagctcg tcgggcgggt ggcgctcgcc gggatgatcc gcggcatccg
    10501 cggcaaccac tccatcaaga agatccgccc gcaccggttc gcccgcttcc acctgaccaa
    10561 ccgctgccag ctccagtgcg tgcactgcta caccagctcc agcccgttcc tgcccaagga
    10621 cggcgagctg agcaccgagc gctggatccg gctggtggag gacttcgccg cgaacggcgg
    10681 ggagaaactg ctgctcaccg gcggcgaggc gctggtgcac gagggctgca ttccggtcat
    10741 gcggcgcgcg cacgagctcg gcctcgaggt cacgctgttc tccaacggaa tggccgtgcc
    10801 caagcacctc gacgacctcg cccgctacgc cgacatcgtc cagatcagcg tggacgggcc
    10861 cacggcggag atccacgacg ccatccgcgg ccgccattcc ttccgccgcg ccacgcgcgc
    10921 gatccggctg ctcctcgacg ccggcgtcca gacgcaggtc agcacgacga tcatgatgaa
    10981 caactgggcg gccatcaagg cggggctgcc cgccttcatc gacgagtggc gcgacagcga
    11041 cgtgaagttc aggatcagct acggcgccat ggcgcacggg cgcggcaccg acctcgacca
    11101 cgacctgaac gaggacgagg tccgggactg ggtcgacgaa ctgctcggcg gcctccgcat
    11161 cggcgacgac aaggcgcacg gccccaacaa ggtgcagaag ataaacagct gcggatacgc
    11221 cgagcagctc gtcgtcgcct ccgacgggat cgtgtacccc tgccatctgc tgtccggcgc
    11281 gctcgggcac atcgaccagc tgccgctcag cgagatcacc gactatctca agcggacgtc
    11341 cgacgccttc accgtcgaca accggaaggg ctgccagtcc tgcgacctgc gcaacctctg
    11401 cggcgggacc tgccgggtcg aggacgagaa gcacaccggc agcaggttga tcaccacgtg
    11461 cacgcccgag gagaaactgc gcaggcggcg tttcctcgtc cgccgctaca ggccggttcc
    11521 gggcgccgcg ccggaggtcg ggtccgaagt cgggccgggt tcttcgtgac gctcgccgac
    11581 ctcctccgtc ccagggccgt ggcggatttt ctcgacacgg aatggacgcg tgagccgtgc
    11641 gtgttccccg gcgccgccaa aggggccgcg ctgctcgacc tcgacggttt cgaggcgatg
    11701 ctgggcgggt tgcattacgc ccatgagggg ctgctgcacc tcgcccacgg cgaccgccgc
    11761 cgccttccgg ccaccttcat ggacgcggac ggaatgctcg acctgcgtca ggtaaggaag
    11821 gccttcaagg gcggcgagac gctctacctg accaaggcac atcggctttc cccggttctt
    11881 gccgacctgt gccgcggtgt cgaactcgac ctggccgacc acggggtcgt cctccggaaa
    11941 ccggccggcg cccacgtctt cgccacgcct ccgtcggcgc agggattcgc gccgcatcgc
    12001 gacgagcacg gaagcctggt cgtccagacg gagggccgga aggcgtggat ggttgaggaa
    12061 aggcccggtc cgccacggcc cggcgcgatc tccccccagg aatgggcgaa gatccggttt
    12121 cgggagttcg cgctggaacc gggagacgtg ctgtacgtcc ccgaatactg cgggcatgcg
    12181 gcccgcaccg aggaagcgca ctcccttcat gtgacgctca ggctgttccc gctgcgctgg
    12241 cgagacgtcc tcgacgaggt cgtgggagcc ctgcccgccc tgaacgcgtt cgtccctgcc
    12301 gcgcgcacgc acgaccccgc cgccctcgcc accggcctgg ccgagctcct ccgctccccg
    12361 gacgtgggcg cggcactgcc cggcctgctc gccgggctgg ccgcgcggcg gaccgagcgc
    12421 cgcgccgtcc tgccggacgg cgggctgggc gggccggacg gcatcgacga gaacacctgg
    12481 ctcgtccgcg cccggggcgc cgactgccac gtgaccagcg gcgacgacgc cgcgacgatc
    12541 cacttcccgg gcggcgccgt ccgggggccg atcggcgtcc tggcggcgtt cgagcacatc
    12601 gcgaaggcgc gcgtgctgcg cgccgccgac ctgcccggcg cgctcgaccc ggacgcgtcg
    12661 ctcggcgttg tgcgcaagct ggtcgccgac ggcctgctgc gccgcgcccg ccccggcgag
    12721 accgcggaga ccggcgagtt cggcgagttc gcgcggtgag ggcgcggccg atcgtcttcc
    12781 tcgggccgtc gatgccgctc gccgaggccc gcccgatcct ggacgccgac taccgccgcc
    12841 cggtccggcg cggcgacctc gacgcgatcc ccgccggcgc ggtcgtcggg atcatcgacg
    12901 gcgtcttcga gcagaccctg tccgtcagcc cgaccgaggt gcgcgcggcc gtcgaccggg
    12961 gggtcgtcgt gtacggcggc ggcagcatgg gcgcgttgcg cgcggccgag gtgcccgcgg
    13021 tcaccggcgt cgggctggtg tacgcctggt accgcgacgg caccgtcacg cgggacgacg
    13081 aggtcgcgct gctgttcgac gaggagaccg gcgcaccgct gacggtgccc gccgtcaacg
    13141 tccgctacgc cgtcgaacgc ctccaccgga cgggcaccat cgacgcgtcc accgccgacc
    13201 gcctgctcac gaccgcgttg gaactgccgt tcaaggcgcg cacctaccgg cacatcgtcc
    13261 accgcgccgg cctgctcgga cgcgccgacg gcgcggacct cgtcgccatg ctggcgagtc
    13321 acgacctcaa gcaccgggac gcccagtcgg tcctggaggc gatcggcgcg gcccgtcccg
    13381 tctccaggaa gggcgcagca cctcgcccga ccgcggcgac gcccgtcccc gaaccgatca
    13441 ccaccggaac cgcgctgatc tgggagagcg gcgaccgggt cggcgacgag gaactgttcg
    13501 cgttcctcgc ctacaccggg cggctcgaac cctgggcccg ctccgcccat cccgtcccgt
    13561 ccgagttcgt ccggccggtc gacgcgcccg ccgcgcaggc cctgttcggg accgccgtcc
    13621 gccggtgggg gtggctgagc tcggaggagg cacgcgtcac gctcgcggat ctcggcatgg
    13681 acatgcccac cctcaaccgc agggccgagg cggaggccgt cgcggaggcg ggcctgacgg
    13741 cgtgggcgaa ggccgatccc caggcgttcc ggcgctcgct tcgagcggcg ctcttcctgc
    13801 acgacgcgtc gctgaaacgg gaggtgatgc gcctcggagg actgaacctg ttcgccgagc
    13861 gggacccccg tccggcgtcc accgaggaac tgtccgatgc gtggcaggtg ctgtgcaagg
    13921 cgaacctggc cttcgacatc gaggccgtgc ggcagcggtg ggcccaatgg ggatacggcg
    13981 atcgcgccgc gcaggacgcc ttcgtccaca ggctcgcgcg ggcgcgccgc gcgggcgggg
    14041 aactggccgc caccatggcg ggacgagccg ctcccgccgc cggtccggtg ccgcatcccg
    14101 acctgccgct gcgcgcccgg ccgaagcccc cggacgagcg gcgcttctgc ctgcccatgg
    14161 ccgaggcgcg cgaccacgcg acccggctgg cgaagacgat cgggatcacc cggatcggca
    14221 tggtcggcga cctcggggac ctcggcggcg tccagatcgc ccaggccgca cgtcccgacg
    14281 gatgctggtc cagcacgtac gggagcggga agagcctcag cgaggacggc gcgcacgtcg
    14341 gcagcgtcat ggaggaactc gagaaatggg cccaggagca atgggtgccg cgcgccgccg
    14401 acctcgtcca ggccccctac cgcgacgtgg ccggcgacgc cgtcgacccg gcggcgctcg
    14461 cccttcccta tgacagttcc tacgcccccg accggccgct gacctggacg cggtgcccgg
    14521 acgtcctctc gggccggacg gttctcgtcc cgctcgacct gctgagaatg gaacgcggcc
    14581 cccgcgacat ctgcttcagc ccgcgcggcg cgcggaaggt catcgccacc aacggcctcg
    14641 gttccggctt ctcccgggag gaggccctcc tgcacgggct gtgcgagtac gtggaacggc
    14701 acgcccagcg cctcgcggag atcgccctgg tcaacccggg cgggacgggc gcgccgccgt
    14761 tccggttcgt ggacctcgac accgtcccgg accgcgcgcg cgaggtggcg gagcggctgc
    14821 gccgggtcgg gctcaccgtc cgcgtcctgg acatcacggc ggacgtccgg atccccacgt
    14881 tcatggcgac cgtctggcgc gacctgaacc gctccgaggg ctacggcacc catcccgacc
    14941 ccgggacggc ggtcgagatg gccgtgctgg aggcggcgca gtcgatcgcc tgcgcggtcg
    15001 cgggaggccg cgaggacctc acgatccagg cccgcagcct cggccgtcac gagcgtcccc
    15061 gtcccgtcgc gcgcgaggac gcctggttct ggctcgaccc cgatgtcgcg cccgccccca
    15121 tgacgcaggg gttgaccggc gacgacgtcc tcgacgacct gtggtgggcg ctgggacggg
    15181 tggccgacgc cggcctcccg cacgtccccg tgctcgacct gacgcacccg gagatcgacc
    15241 ccgcgcacgt cgtccgggtg atcgtccccg gcctggagag caacaacccc ttcgccaccg
    15301 gggaacgcgc ccggctgtcc ctgctccgcg acctgctccc ccgctggtcc tgaccccgtc
    15361 cggaggccgc catgacgaca acggaactcg accttcggca ggtcgactcg accgtccgca
    15421 ccatcggcga gcacggttac gtgctcctgg agaacctgct gcccgcaccg acgatcgacc
    15481 ggatgcggga ggccctggaa aggctgctgc acgaggagaa ggcgcggaac ctgcacccga
    15541 gcgggcacca gcgggtcctg cacgtcctgg tcaaggaccc cgtgttcgtc gacgccctcg
    15601 tgcacccgct cgtcctcgcg gtgtggcggc gctacctcag cgaggacctg atctgctcga
    15661 cgttcaccgc gaactccctg tggcccgggg cgaccgagca gtactggcac gccgaccacc
    15721 cgtactggac gctgacgccc ccgtggccgt cgatcccgct gtccgggcag tgcatctggt
    15781 tcctggacga cttcaccgac gagaacggcg ccaccgccgg aatccccggc tcgcaccgcg
    15841 cggaccggct gcccgacatg ggcgagtcct ggtgcgacga gggcgagatc ctggccggcc
    15901 ccgcgggcag cgcgatcttc gccgacggcg cctggtggca cacctcgcgc cccaaccgca
    15961 ccaccgccct ccggtccgcc ctcctcgtca cctacaccca caccttctgc gtcccgcagg
    16021 aggacatgcg cgggcagctg gacgcgctga gcaacccgtc cgacctggtg gtcgagctgc
    16081 tgggaggaaa gcagtaccaa ccccgacgcg acttcccgta ctagcccacg tcgtctcccc
    16141 cgggctgccg gcgttactga acgtcgtggc gtcgcggctc tccacccggg gcgtgtgcca
    16201 gcggtccatc gagttcagca ccgcatctcg gcggcccgga aggctgcggc cgcgtcgggc
    16261 aggcggcgcg acctgaaggt cgttgatcgt ccttcagtca gcgggccctc cgagggggcc
    16321 accgccggga acgactcgcc catcctcgac cgcgtacctt ttcgagttcg cggaggaggc
    16381 ggtccggaac ggtctgccct tgttgttgat cacgacgaaa ccgggttttc cgtcggcgac
    16441 gaaatggagc ttcgcggtcc accagcaatc atgcttggac gcgcctgccc ataagtacag
    16501 cacctctggc tcggcctgtg agacgcggag cggaaacgac cacgtgccac ctgtgtcctc
    16561 ccccgagacg ttgcgcaggt ccttgatcat cggggctgcc tcgtccaggt ccgtggcgtt
    16621 ccttccatcg accccatcgc ctcctggaaa gaccttgacg taagtcgccc ggggaggcgc
    16681 ggcccggccc aggacgtcga tccggaagtc ggtgagcacg accgacttgg cggacgtccc
    16741 ctggatgacc agttcaaggg tggtgatgtc ggcatcgacg ccgccattgc cgtatcccca
    16801 cttctccacg agttgctggt cattgcgata gccaggcgga agtgatggca gcgcggcagc
    16861 gggcttggag aagatgaagg cttggtcgcc ctggacggcc cgaattcgtt gaatcggagt
    16921 gacggatctg gttaccgaga gcggcgactg gctgggagca ggccgtggcg ccctctgggg
    16981 ccgaccgtgc aggatccaca ccccgcctgc tgccaggatc gaggtggccg cgaccgccgc
    17041 cgcccatgtc cagcgccgcg tcggagaagg tcggtgcccc ggtggcgcgt tgccgatggt
    17101 gatgttcccg cggacgtcgc ggatctggaa gaggctgcct ccgacgcgac tgccggagac
    17161 ctcctggccg tcgcctgcgg ggtcctcggc cgcaggatcg tcgtcgcgcg gtggagtggt
    17221 atcgcgcatc aggtgtctcg ttcgatgtcc acgtcgccgg cgacctggtc gatctgagag
    17281 ctggatccgc tgatccgcgt gccggtcatc gactggatgc caggcggatc tgccggtgga
    17341 gtcgtcccac ttggcggctg gtgtggtccg cctgggggcg gtggagcctg gggccggccg
    17401 attcgtacgc taccgcccac gccccggact tgaacggcat cgccgccgac tgtggacccc
    17461 tgaatccgct gccctggcgc agccccgggt tcctctggcg gaggcgctgc ttgtgacggc
    17521 ctccggatca gcgccgacag cgacagagcg agacccgcga tcgtgctcag cgctccgatc
    17581 acgctggcgt acttgtccgc gtcatcgagg tcgagcgcga aaaggaacac ccccagccct
    17641 gtgatcacca cgcccgccgc aagccagatc atccaatgca ctcgtgcctg tgttcgggcc
    17701 attgagcctc gatgtgacgg ggaatacgta ctcttcgacc gtacgggatc ccgttaggat
    17761 tcgaagcgga ggcaggggcg cggccgaatg tggccgtgcc agcaaatacc cccttctctg
    17821 ccatactgcc ggcagcttca tgatcgggat cggatcgccc tccggggggc ttgaccgacc
    17881 ggcgggtccg tgctccaacc gagagcctat gacctagggc gaatcacggt gccattgcag
    17941 caagagtaag cgacgatcga ggagccacgg tgggccagct ggggcggcac cggatggcgc
    18001 ctattccatc gtacagtttc agggtgcact cggaatgatc ggcacggtag ccggcaatca
    18061 gaccatcaac attccgagca ccttcaacga ccgaacctca tcgatatgga ctccgccctc
    18121 gtcaagaacc ggatgcacga ggctgaccct gtggtcgaac tcgaacggcc atggtgacgc
    18181 atggattcat gagttcaacg acggcggcgc ggcgaatgtc ccgacctgga tgaacgacag
    18241 ggcatcatcg ctgaccgttg agtagcgaag gtctccgcgg ggtcgtcgac gacaacgcgg
    18301 agaccacccc ttcacccccc gatggcacag agagcggcgc gctgcggtcg gccggcgtct
    18361 ccaacacccg cttcgcccgc tgcgacgcgg atacgctcgc ctggcgtctg gcacagtggg
    18421 gcgccatgat gagctgctcc ttttgccgtc gcgagtacga cgagaacgat gccgaggccg
    18481 tcgagctcca taccgagccg gtcgcctgcg acgcgcggcg gacttgtcga tgccagggca
    18541 gacccaggtg ctacgcgtgc ggtgactcct tctgcttctg cgccgcacac tgatccggag
    18601 tctgacaagc tcccctaccg ccagccctgc atccgccgcg tcacgttgcg tgcagacctg
    18661 ccggtacctt gatcgccgtc cggccgcccc atcgtcggct tgctcatcac ctccgcccgg
    18721 cggaggatag gggccaggct ccgcccgacg ggagatcagg tttggacgcg acgaccgaac
    18781 acggcgacac gctcggctat ccgtggaccc tgcgagtgcg gatacagcat ggccaactgc
    18841 tggcccggct ccacctgacc accatcgaac gtgaatcgct tctgcactgc gacctgccgt
    18901 gcgacgcggt ctgcgtccac gtcggactgt cagcgaccgg cccggttcgt gtgctggtcg
    18961 ccgccccgcc gtccgccgag gcgatgcgcg tccgcaccgt cggcggacgg ctgacgcccc
    19021 tggcggtgcg gcacccggcc ggcgccccgg tcgcgatcgg cgccgcactc ctggagcgcg
    19081 acgatccgcc cgtccggctc cacgtgctcg acgcatccgg cggcgaccac gcggagccgc
    19141 tggacgatcc ccgcctcggt cccgccgcgc gccctcatcg caccctgctt cgccgccgcg
    19201 gacccaggca gttccgccta gccggttagc cggtcacgga cggggcgcag cgggtccagc
    19261 ccgccgccca ccccggcatc cgcgcgtcct gggccacacc gacgctcgag atgcggccca
    19321 ctaggcgacc ggactcgttg aacgtgagga cctcgcggtc agaataggca gcgccatgct
    19381 ggacgatccg gagcgtgcgc aacccccgga cggtctccca cgcgttcggc cgccccttga
    19441 ccggcctggc gccggacggg cgggccgggg gaccgaggac gtcgtcgagt agcgcgtcca
    19501 gggtgtccaa ccggggctcg ggcggatcct ccacaccctc ctcgcaggtg gcccagtccc
    19561 ggacggcgaa cgcctgaggg agactccggt cccagcggct ctcgtacacc ttgaccccgc
    19621 cgggcctgct ggtcagcgag tgaatggtca tggcctggcg gccccgcagg ctcacccaga
    19681 ttcgcacggt ggtcacggcg ccctcgcggc cttccccgcc ggagtaagag gtctcggtga
    19741 actccagccg ggtcaccgtc gccgggccct cgcggtgcgg cgcaccgccg ccgttgccgt
    19801 cgcaggcggt cagcagcgcc gaggcggcca gcgcggcgca ggctgcggct cccgccggcg
    19861 cgcggcccgt ggtgaagaca aaggtcacgt tgcgcctccg gggcggcgcc gggccgatgg
    19921 gggtcggccc ggcgagacgt gctggtgcac gtgtccggct gcgactagca gcggaaccgc
    19981 cgctggtcgg acgccgcagc gcggtacgtc ttgcccttgt ggaccgcggt cgcccgggcc
    20041 cggacgcggt aggtgtaggt accgccgcac ttcttacgtg agacgctggc gaccctgcgg
    20101 gtgttgcggc ccccgctgtg gtcggtgtcg agctgctgcc aaccgtagaa gcgcttgcgt
    20161 gcgaggtcgg tccacacatc gacccgcgcg acgttgtacg gaccatgggc gatcgcctgg
    20221 cccttggcgt acttgcccga cttgtaggcg agtggcgtca gataccagcc ggggaggacc
    20281 cggactcggt gatcgggctg cgtctgctgc gtctggaacc gggccgcggc cggctgcgcc
    20341 gacgcccgga cgtcggcatt ggcctgcccg cctaacgcca ccaccgaggc gagcgcgaag
    20401 gcgctcgtcc caagggccag cgtcgccgtc ttgagcctca tgctttctcc ttctgttccc
    20461 atcgaccgtc gtgaccgaat tggttaaagg aacgctacag agcacgctcg ctcgcccaaa
    20521 tcgtggagat cacgcacaac ggagaattcg gcatcagcga cgcgcgtctg tcaatcgtgg
    20581 cggccacgta aagtctgatc agtgcgctgg gcagacgcgc tgtcttttac ggcgatgacc
    20641 tggggaccct tgtgcagggt agcgctgaga atccgggaaa gtgcaaggcg taaggaggag
    20701 gcagaaggcc ggaaaagctt gtactgcctg aatcaggacg aacgccggtg gtgcggacga
    20761 tgaaccagcc gagggtcatc gaccgtgctg agagaacgat tacggcgctg tcggcggacc
    20821 cagaggccag gttccggaaa ccataatata gaagcgatgg cgctttaggc cacgagcgtt
    20881 cctcggccat ctcttccaca ctggacgtcc tgtcctgagc agcccggttt cagaggcctc
    20941 aacggccctt tcggtccgtt tatccaacga ccgtcagagg aacacgttgt agcgcacgaa
    21001 cgatgacggc catgatgcgg ctgcgtccca gcaggaccga ggcgactgga attcgacgga
    21061 cgggtgcgcg gccgctcgcc gttcaacgat ctggtggcac tcgagggctg cacctgccgg
    21121 tgcctgccgg tcgggggcgc ggcgagtgcc ggtgccagcg gcgctcgccg ggccgacgtg
    21181 ctcgtgccag gccgccgtcg caacgcgcag tcgcgccccc gaccggcggc gcagggtccg
    21241 acggccgagc cggtcatcgt gacccgggtc ccgccggatg aacgtcgaac ccgctgccgc
    21301 cgctgacgtt cgccgacgag cgggtcatga tcgccgcggt cacgcggaca gagccttggg
    21361 aggaggtcgg cttcccaagg ccctgtggcc atgcgctacg cgggcgcttg tgatcgctac
    21421 ttcggcgtgt acaggcggac gtcgtccacc cgggcgctcc cctcgtagaa gttcatgtgc
    21481 gggtcgccga tcatgaagtg gtcggggtag gcggacccgg caggccaggt gtcgcggtcg
    21541 acgagcgtgc cgccggggcc cttccaggtc cagtcggcgt tgtagcggcc gtcgtactcg
    21601 gagggcttct ggttgtagtg ccagatcggc tcgccgtcct ggacgaacga gcgcgtgtac
    21661 cggaaggtcg ccttgcccac gtgcgcgaag ttgcccgaca tctccatcgt gtacgcgccg
    21721 ttccgccgct cgaccgcgaa ccggtagggc tccttgggca gcagttccgg cttcaggtcg
    21781 atggtggaga cgatcgcgcc gcccttggcg agcccgcact ggctctccat caggtactcg
    21841 gtcccgggca tcgtcgggta gcggcggtcg tcggtcatga agatggcgtt gacgccgttg
    21901 cccgtcccgg cggtgtaggg ctcgtactgc ccggtcgcgg gattgcagta gcgcaggccg
    21961 gcgccggtgt acttgtacct gttgtagccg tccatggcga ccttgcggtg cccgtggacg
    22021 aacacgttgt tgtgcggcgc cacccgcccg tagtccatga tcgacatgta gtagaagccg
    22081 ttggagtcgg tgcggacgtc cgcccactgg cactcaggac gggagaagtc gccgcccgag
    22141 gcccatggga agttcgtctt gcagccctgg ggcgagtagc cgttgatccg gccgtcgggg
    22201 tagtcccacg acccgttccg ctgcccgccg aagtcgaggc cgcgcagcgt catctccacc
    22261 cggtactcgg cgggcagcgc ccgcgtcgag cggatcacga cgcccgcctg gtggctcggc
    22321 tcgtccaggc gggcgacgcc gccgcgcgag gtgagcgtgg gcggggcgtc cggcctgccg
    22381 tcgccgtcgg cgtcgcgggc ggcgagttcg gcggtgagcc agccgtgttc gccgaacgtg
    22441 aacgacttgc ggtaagtgct catcttcgtg agctgcgtct ggaacgccgg gcccccgacc
    22501 gtgtcgaaga aggcgccgtc gttgtcgtac atgtcgacgt tgtagggact tgccggaccg
    22561 tcgccgtcgg acctccaggg caccttcgcg tcgtcaaggc gccggtcgaa ggactcggcg
    22621 tccagcaggc gccagcccgc cagggtgggc ggcgccgccc ccgcgtgcgc cgcccccgcc
    22681 agggtcatgg gcatgaccag ggggaacgcc agtgccagcg cgccccgcac gaatctcttc
    22741 atagctcgcc ccctccgcgc cgcgcctccc gcgcggcgct ccgccggaca tcgggtgatc
    22801 ctcggtgacg gtaggtcggg gtggcggcga acgccatggc aaaacccgcc aaagtggtat
    22861 tgaccagtcg caacaaccgg acatatcgtg tgcccggaca ggaacggcgt atccgggagg
    22921 tgaacaggtt gcgatccgcc ggtgaggccc ggaacgggaa cacgaaacgg caggcggtgc
    22981 gccgccgcct gctggagatg ctggacgggc tggacgtcgg cgacgccctg ccgtccgagc
    23041 gccggctggc cgccgacctg ggcgtctccc ggccgacgtt gcggcaggcc atcgacggtc
    23101 tcgtcgccga gggcctgctc caccggcggc acgggagcgg aacctatgtg tccgaacccc
    23161 ggatcgccgt ctcgctgacc atgacctcct tcaccgagga catgatcagg agggggatgc
    23221 ggccgggcgg ccgggtcctg tcgttccgca cggaggccgc gggggcgcgg atcggcaggc
    23281 gcctggccgt ctcaccgctg gaagaggtat ttaccattcg gcggctccgg ctcgccgacg
    23341 aggccacgat ggcgatcgag accctctaca tgccccgggc gctgatgccc ggcctgcgca
    23401 ggcaggacct ggagggccgg tcgttctacg agctgctccg cggcagcggc gtcgagatcg
    23461 cctcgggcac cgagacgatc gagccgaccg tcaccaccga ggacgaggcg gcggaactcg
    23521 gcgtgccggt gcacatgccg gcgttcctgt tcgagcgggt gaccagggac gcgggcgggc
    23581 ggcccctgga gtacgtccgg tcgctctacc gcggcgaccg ctaccgcctg gaactcgatc
    23641 tcagaccacc gtcgcactga ccggagtccc ggagcgaccc gccccgggac tcgatcgtcc
    23701 aaccgcgctg acgggggcga cagcgcacga ccccaccccc gagaagtgag gcgattcacc
    23761 catggacgtc atcaaggaca tcctgacctt cctggccgac aacgtgttcg gccaggtgcc
    23821 catcctgatc gggctcatca ccctgatcgg actgctgctc cagcgcaagc ggttcgagga
    23881 cgtgttcgcc ggcgcgctgc gctcgacgat cggcgtggtg atcctgttca tcggcgtcga
    23941 cgtgttcacc ggcgggctga ccagcttcca gacggtgctg gccagtgcga tgggcacgac
    24001 gccgccgaag gccgaccact cgctcacgca gttcctgacc gaccagggcg ggacgatcgc
    24061 gctggtcatc accgtcgcgt tcctcgtgca cgtgctggtc gtgcggctgt tcccggcggc
    24121 ccggtacctg tacctgaccg gccacctgat gttctgggtg agcacggtca cggtcgcgtc
    24181 gctggtgacg atcgcgccgg gccaggacca gctcacgctc gtgctctgcg gggccgggtt
    24241 cgtggccgct tactggaccg tccagccgct gtggatgcgg cccctgatgc gccgcgtcat
    24301 gccggacgac cggttcgggt acgcgcacac cagctcgctc acctgcctga tcaccgggta
    24361 cgcggcgcgc ccgctcggga gccgggagaa gcacgacacc gagaagctga agctgccgcg
    24421 ccagctgtcg ttcttcaagg acgtcaacgt cagcacggcg ctgatcatct ccgtgatcat
    24481 gctggtggcg gtcgcgttcg ccgacaacgc cgtggtgggc aaggccgcgg ccgagatgga
    24541 ccccaagctg tcgtcgtggg tgtgggcgct gctggtcggc ctgcggttcg cgggcggcat
    24601 cgcgatcctg ctgttcggcg tgcggatgtt cctgggcgag atcgtcccgg cgttcaaggg
    24661 gttcagcgac aaggtgatcc ccggcacgcg tcccgcgctg gacgcgccga ccgtcttccc
    24721 cgtcgcgccg accgcggtga tgctcgggtt cgtcgtctcc accggcgtgt tcctggtctg
    24781 cctggcggtc ttcgcggggg ccggctggtt cacgctcgcg ccgcccatga tcatgctgtt
    24841 cttcgtcggc ggcgccgccg ggctgttcgg caacgtcgtg gcgggctggc gcggggcggt
    24901 gctcggcggc gtgatctcgg ggctggtcct cgcgatcggg cagtcggtca cctggggcct
    24961 gtacgagcgg accgcgccgg agctcgccac cctcgccgac cccgactggt acgcgatcgg
    25021 ctggctgctg aaggccgtgg acccggtcgt cggcgacggg tcgatctggc tggtgcccgc
    25081 ggtggcgctg gccgcgatga ccgcgaccct gctcgtcctc gggcgggccg agaagcgccg
    25141 ggccgtcgcc gaggacgccg gctcgggcga tgacaaggcg atcgtgaacg cctgacggac
    25201 gcgcggaacg ggaacgcccc gagggggcgg cctcgcgggg cgcccggccg aacgtcaacg
    25261 aaccgacaag ggagtgaccc gatatggcac tggaccggca actggagatc ctcgcggtct
    25321 gcggcgtcgg catgggctca agcctgatgc tga
//
