LOCUS       NZ_JAICDG010000003     22559 bp    DNA     linear   CON 29-AUG-2024
DEFINITION  Actinomadura terrae strain OS3-83 contig3, whole genome shotgun
            sequence.
ACCESSION   NZ_JAICDG010000003
VERSION     NZ_JAICDG010000003.1
KEYWORDS    WGS; RefSeq.
SOURCE      Actinomadura terrae
  ORGANISM  Actinomadura terrae
            Bacteria; Actinomycetota; Actinomycetes; Streptosporangiales;
            Thermomonosporaceae; Actinomadura.
REFERENCE   1  (bases 1 to 1091803)
  AUTHORS   Lee,S.D., Yang,H.L., Kim,I.S., Choe,H. and Kim,J.S.
  TITLE     Actinomadura terrae sp. nov. and Actinomadura litoris OS3-89,
            isolated from rhizosphere soil of cactus
  JOURNAL   Int J Syst Evol Microbiol 73 (1) (2023)
   PUBMED   36748505
REFERENCE   2  (bases 1 to 1091803)
  AUTHORS   Lee,S.D.
  TITLE     Direct Submission
  JOURNAL   Submitted (15-FEB-2022) Institute of Jeju Microbial Resources, BioPS
            Co., Ltd., Sancheondan Dongil 16, Jeju 63243, South Korea
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: SPAdes v. 3.13.0
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 141x
            Sequencing Technology             :: Illumina
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_022751215.1-RS_2024_08_29
            Annotation Date                   :: 08/29/2024 06:12:19
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.8
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 8,085
            CDSs (total)                      :: 8,002
            Genes (coding)                    :: 7,936
            CDSs (with protein)               :: 7,936
            Genes (RNA)                       :: 83
            rRNAs                             :: 5, 4, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 3 (5S)
            partial rRNAs                     :: 2, 4, 4 (5S, 16S, 23S)
            tRNAs                             :: 67
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 66
            CDSs (without protein)            :: 66
            Pseudo Genes (ambiguous residues) :: 0 of 66
            Pseudo Genes (frameshifted)       :: 13 of 66
            Pseudo Genes (incomplete)         :: 56 of 66
            Pseudo Genes (internal stop)      :: 3 of 66
            Pseudo Genes (multiple problems)  :: 4 of 66
            CRISPR Arrays                     :: 4
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 21:31:58
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 619635
            Orig. end                         :: 642194
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            JAICDG010000003.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..22559
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="lanthipeptide-class-iii"
                     /region_number="4"
                     /rules="(micKC and not PKS_KS)"
                     /tool="antismash"
     cand_cluster    1..22559
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(micKC and not PKS_KS)"
                     /kind="single"
                     /product="lanthipeptide-class-iii"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..22559
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:12559](-)"
                     /cutoff="20000"
                     /detection_rule="(micKC and not PKS_KS)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-iii"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..12559)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(micKC and not PKS_KS)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-iii"
                     /protocluster_number="1"
     gene            complement(761..1768)
                     /locus_tag="K2F47_RS22650"
     CDS             complement(761..1768)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012852234.1"
                     /locus_tag="K2F47_RS22650"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="ADP-ribosylglycohydrolase family protein"
                     /protein_id="WP_242906881.1"
                     /transl_table=11
                     /translation="MTTTRRASGAMFGLAYGDALGAPTEFLSMEQIRQRFGDLGPERPE
                     GDPALVTDDTQMAIAVGLALLDALDDPPFTADRVEPLWRRRFVDWLDSPDNDRAPGNTC
                     LTACRGLATPVPWTEATVPGSKGCGANMRVAPVGLAPGLTDETRAAAAQLQAAMTHGHP
                     TGLAASELTAFAVRWLADGMAPADLPDALRDRCYEERTTYYGEWLGDLWRASGSDDPWR
                     FISRGWEECIDALDRLDAALAGPDRAADPCETTGAGWVAEEALAAGLLCFLLFPDEPVT
                     AIRRAAASSGDSDSIACLAGAFAGAHLGMDAWPGEWAARIEYADDLGRIGAAWD"
     gene            complement(1811..2053)
                     /locus_tag="K2F47_RS22655"
     CDS             complement(1811..2053)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018657903.1"
                     /locus_tag="K2F47_RS22655"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="hypothetical protein"
                     /protein_id="WP_242906883.1"
                     /transl_table=11
                     /translation="MDEREGRRGDVQELSEFELAVYETVAEIDKEGGAADFDTVSRLVA
                     APEEELWAALGHLVEVNHLHSTPKGYVLGPHDWAP"
     gene            2194..2925
                     /locus_tag="K2F47_RS22660"
     CDS             2194..2925
                     /NRPS_PKS="Domain: Thioesterase (15-239). E-value: 1.9e-60.
                     Score: 197.1. Matches aSDomain:
                     nrpspksdomains_K2F47_RS22660_Thioesterase.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Thioesterase"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Abhydrolase_6"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1004: thioesterase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019634304.1"
                     /locus_tag="K2F47_RS22660"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="thioesterase II family protein"
                     /protein_id="WP_242906885.1"
                     /sec_met_domain="Thioesterase (E-value: 2.6e-56, bitscore:
                     187.2, seeds: 16, tool: rule-based-clusters)"
                     /sec_met_domain="Abhydrolase_6 (E-value: 6.4e-11, bitscore:
                     39.1, seeds: 455, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTWFRCAEPRPWASTRLFCLPHAGGSAVSYRSWAKEADPSVEVHA
                     VQYPGRADRLAEPLVGDAHELARLVADAMVPLLDRPAALFGHSMGAVVAYEVARLLQER
                     GSAPVHLFASGARPPHDRDDDRVSERDDEGVVAEMVKLGGTEAEILADPELRQLVLPYV
                     RNDFALVENYAHRPGTRLDVPVTVIVGNDDPHVTPAQAERWAELTGGPFAMTVMEGGHF
                     YLTPHQSAVIAEIHRALGVAA"
     aSDomain        2239..2910
                     /ASF="active site serine inconclusive"
                     /aSDomain="Thioesterase"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_K2F47_RS22660_Thioesterase.1"
                     /evalue="1.90E-60"
                     /label="K2F47_RS22660_Thioesterase.1"
                     /locus_tag="K2F47_RS22660"
                     /protein_end="239"
                     /protein_start="15"
                     /score="197.1"
                     /tool="antismash"
                     /translation="RLFCLPHAGGSAVSYRSWAKEADPSVEVHAVQYPGRADRLAEPLV
                     GDAHELARLVADAMVPLLDRPAALFGHSMGAVVAYEVARLLQERGSAPVHLFASGARPP
                     HDRDDDRVSERDDEGVVAEMVKLGGTEAEILADPELRQLVLPYVRNDFALVENYAHRPG
                     TRLDVPVTVIVGNDDPHVTPAQAERWAELTGGPFAMTVMEGGHFYLTPHQSAVIAEIHR
                     AL"
     CDS_motif       2431..2496
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_K2F47_RS22660_0001"
                     /evalue="3.40E-09"
                     /label="NRPS-te1"
                     /locus_tag="K2F47_RS22660"
                     /protein_end="101"
                     /protein_start="79"
                     /score="29.1"
                     /tool="antismash"
                     /translation="RPAALFGHSMGAVVAYEVARLL"
     gene            complement(3058..4164)
                     /locus_tag="K2F47_RS22665"
     CDS             complement(3058..4164)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018657892.1"
                     /locus_tag="K2F47_RS22665"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="S1 family peptidase"
                     /protein_id="WP_242906887.1"
                     /transl_table=11
                     /translation="MKIRHARISGAAVTMTATGVMASALVAAPAANATPQAPASPAQAA
                     QASVLTTAQAAQARTATTLAQRLGSRTAGSYIDAATRQLVVTVTDASAARAVRAAGAQP
                     KTVARSGSDLKKVMAALKRDATVPGTAWAVDPASNTVLLSLDSTVTGSRLAKVRKAVAK
                     QGAAVRTERIAGTLRPFTRGGEAIWTSGGRCSLGFNVKKGGEYYFLTAGHCTNIGTAWY
                     SDQGHTKLLGNTENGSFPGNDYGIVKYSSAPEDTQGSVSLYGGTQDITSAGTPTVGQTV
                     QRSGSTTHVHSGRVTGLNQTVNYQEGSVTGLIKTTVCAEPGDSGGSLFAGATALGLTSG
                     GSGNCSSGGTTYFQPVTEPLQVYSAQVY"
     misc_feature    4252..4265
                     /note="TFBS match to CatR, H2O2-responsive repressor,
                     confidence: medium, score: 19.02"
                     /tool="antismash"
     misc_feature    complement(4292..4310)
                     /note="TFBS match to LexA_variant_3, Repressor of DNA
                     damage response, confidence: weak, score: 18.53"
                     /tool="antismash"
     misc_feature    complement(4294..4310)
                     /note="TFBS match to GnfM, Regulator of nitrogen-fixation
                     genes, confidence: weak, score: 18.77"
                     /tool="antismash"
     gene            4404..5381
                     /locus_tag="K2F47_RS22670"
     CDS             4404..5381
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1158: ornithine cyclodeaminase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017539302.1"
                     /locus_tag="K2F47_RS22670"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="ornithine cyclodeaminase family protein"
                     /protein_id="WP_242906888.1"
                     /transl_table=11
                     /translation="MTLLLTRSDLESVFDPAGCLAALRRGFTAGKAGGDAARRVVARPP
                     GPGTATALLPGVVEGIPAYTVKVNAKFPGSRPALRGVVCLHDLGTGELLALLDSATVTA
                     WRTGLAAALGTHVLARPGADAVAVVGAGAQAELVMRGLAALRPVRGLAVHDLDPGRAEA
                     FAARHGARLGLDAAALTSYGEVPGAIREAVRDAGIVVTATWARRPILDAPDVPPGAHVT
                     SLGADEPGKAELAPALLREARVVVDDVGLAAEMGALAGAGPEVERSAVALGDVLAGRAP
                     GRRGETERTVYAPVGLPWQDLALSWAAFEMARSKAVGQEFDFLR"
     misc_feature    complement(5404..5418)
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence: weak,
                     score: 14.29"
                     /tool="antismash"
     misc_feature    5427..5440
                     /note="TFBS match to PerR, Peroxide regulator, confidence:
                     weak, score: 14.58"
                     /tool="antismash"
     misc_feature    complement(5427..5442)
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: weak, score: 17.0"
                     /tool="antismash"
     misc_feature    complement(5432..5445)
                     /note="TFBS match to PerR, Peroxide regulator, confidence:
                     weak, score: 13.85"
                     /tool="antismash"
     misc_feature    5432..5449
                     /note="TFBS match to ArcA, Repressor of carbon oxidation,
                     confidence: weak, score: 15.98"
                     /tool="antismash"
     misc_feature    5435..5451
                     /note="TFBS match to ZuR_variant_2, Zinc-responsive
                     repressor, confidence: weak, score: 14.77"
                     /tool="antismash"
     misc_feature    complement(5661..5676)
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: weak, score: 16.86"
                     /tool="antismash"
     gene            5665..6270
                     /locus_tag="K2F47_RS22675"
     CDS             5665..6270
                     /GO_process="GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1016: LuxR family
                     DNA-binding response regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012891201.1"
                     /locus_tag="K2F47_RS22675"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="response regulator transcription factor"
                     /protein_id="WP_242906890.1"
                     /transl_table=11
                     /translation="MIRILLAEEAPLLRGGLVAFFGGVKDLDVVAAIDSGDHLVRMANL
                     RRPDVALIDVALPGLDGFSASRRLREELPDCRTVLMSGRHRTGDLRRAVTARAAGLVLK
                     DTSPGALVDAIRRVAGGQRVVDAELAFSELGSAVSPLTERESEVLELASRGASAAQIAE
                     DLVLTIGTVRNHLSRINRKIGARNRVHAIRIAEEAGWL"
     misc_feature    5797..5799
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            complement(<6568..8046)
                     /locus_tag="K2F47_RS41460"
                     /pseudo=""
     CDS             complement(<6568..8046)
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1288: ABC
                     transporter related protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: protein motif:HMM:NF012235.5"
                     /locus_tag="K2F47_RS41460"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /product="ATP-binding cassette domain-containing protein"
                     /pseudo=""
                     /transl_table=11
                     /translation="MTSRREAARLLWRTAAGAVRGRPRAASAVIAWSLLEAVPTAVFGR
                     AVAQATDAFVGDRPVRAVAWLAALAVAAIAGAFGSRRLYPALAALVEPFRDDLVRQVTR
                     GALYRSLRGRADTGAVARLTHQVEIVRDTFGGILVVARGFVFAAGAALLGLLALMPEVA
                     LLVLPPLVAGLALFGAAFGAAAVRQRDLVVGEEEIAERTTALAEGLRDVVACGAEDQVR
                     ERLAAAVDAQAAAGRAVARFAAVRALALAVSGWLPLLAVLAAAPWLMRRGATPGMVVGA
                     LAYVLHGLQPALRTLVQGMGGSGLRLAVTLGRILETSAPVPPPLPPVTGAPRERRDDAP
                     AVELRGVTFAYGPSARPVISGLDLVIPRGDHLAVVGPSGIGKSTLAALVAGLLAPLEGE
                     VLVDGRPAGDPSARVLIPQEAYVFTGTVHENLTYLAPDASDEDVGRAADELGLAGLVRD
                     LGGYGASVDPAALTEGQRQLIALCRAYLAPAPLIV"
     gene            complement(8063..9766)
                     /locus_tag="K2F47_RS22685"
     CDS             complement(8063..9766)
                     /EC_number="7.-.-.-"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1288: ABC
                     transporter related protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017539205.1"
                     /locus_tag="K2F47_RS22685"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_242906892.1"
                     /transl_table=11
                     /translation="MTTPTAAGADRLLVGAARHSGGWTGLVAATALADALAAVLLPLAL
                     ARAVDAAPPGGASAVSALWPCVALVLLSATAEVLSELATGCAAARATAWLRHALVRHVL
                     AVGPALRVPPGDVAGRTVGGAAEAGTAPAAAPEAAVALLPPLGALAVLAFLDWRLAVAV
                     AVALPAIVLLLRVFVRDITASAHRYLSVQGTIAGRLAEALAGARTIAAAGTAERETERI
                     LRPLPGLRAEGETMWSVQGGVAARGLLTLLLLQVAAVGAAGAELMAGRVTPGELVATVQ
                     YAGLAAGFGPVLTHVLRLGRARAGARRAAEILEQPAPVHGDAAVPQGPGTLEFRGVSAG
                     GVLDGVDLTVPGGLAVAVVGRSGAGKSLLAALAGRLADPDRGEVLLDGAPLPRLSRAEL
                     RRHVGYAFARPSLFGETVLDAIAFGPCRPPETWLRESARTACAEDFVRRLPHGYATPLA
                     DAPMSGGELQRMGLARAFAHAGRVLVLDDATSSLDTVTEVQVTGAVLDRFGDRTRLIIA
                     HRAGTAARADLVVWLDRGRVRGRGTHAELWRDPSYRAVFGVAEPAGAAGS"
     gene            complement(9884..9994)
                     /locus_tag="K2F47_RS22690"
     CDS             complement(9884..9994)
                     /codon_start=1
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF033212.1"
                     /locus_tag="K2F47_RS22690"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="SapB/AmfS family lanthipeptide"
                     /protein_id="WP_089315262.1"
                     /transl_table=11
                     /translation="MALLDLQGMVSENGGGGGNSSLSLLCHSSHSITICL"
     CDS_motif       complement(9938..9994)
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence: MALLDLQGMVSENGGGGGN"
                     /locus_tag="K2F47_RS22690_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       complement(9884..9937)
                     /prepeptide="core"
                     /locus_tag="K2F47_RS22690_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class III"
                     /score="7.00"
                     /molecular_weight="1675.0"
                     /monoisotopic_mass="1673.9"
                     /core_sequence="SSLSLLCHSSHSITICL"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MALLDLQGMVSENGGGGGN"
                     /leader_location="[9937:9994](-)"
                     /alternative_weights="1693.0"
                     /alternative_weights="1711.0"
                     /alternative_weights="1729.0"
                     /alternative_weights="1747.0"
                     /alternative_weights="1765.1"
     gene            complement(10001..12559)
                     /gene="lanKC"
                     /locus_tag="K2F47_RS22695"
     CDS             complement(10001..12559)
                     /GO_function="GO:0004672 - protein kinase activity
                     [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_process="GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /GO_process="GO:0006468 - protein phosphorylation [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="lanKC"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-iii: micKC"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Pkinase"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) LANC_like"
                     /gene_functions="regulatory (smcogs) SMCOG1030:
                     serine/threonine protein kinase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012853928.1"
                     /locus_tag="K2F47_RS22695"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="class III lanthionine synthetase LanKC"
                     /protein_id="WP_242906894.1"
                     /sec_met_domain="micKC (E-value: 6.3e-245, bitscore: 810.9,
                     seeds: 18, tool: rule-based-clusters)"
                     /sec_met_domain="Pkinase (E-value: 1.7e-10, bitscore: 36.5,
                     seeds: 54, tool: rule-based-clusters)"
                     /sec_met_domain="LANC_like (E-value: 1.2e-08, bitscore:
                     29.9, seeds: 47, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDKRYELYCLADKFFYDAPPTSRETEFDIAARPLPEGWERVRGEE
                     WTVYVPPEQKAPLQGWKVHVTGCAESADEALAGSFDFCVENGIEFKHLHGPGTLRMRNA
                     KYAPRGASGKLVTIYPSDEAELESVLETLGARLAGLPGPYILSDLRIGDGPLYVRYGGF
                     AERRCLDERGELVAALENGEGVLVPDRRNPVFSVPEWVTLPRCLEPHLAARGATTTTDL
                     PYRIEKALHFSNGGGVYQGTDTRTGEKVVLKEARPYAGLAADGADAVERLDRERRILEL
                     LDGIDGIPAARDSFTLGEHHFLVQEFIEGRTLNTFFAERHPMLDPEPEPGKVAAYTAWA
                     LRVHEGVERVVDAIHERGVAFNDLHMFNVMVRPDDSVALIDFEVAAPAADGGRQTLANP
                     AFLAPPDRRGTEVDRYSLACLRLALFVPMTTLFVIDRGKARQLADLIAEYFPVPRPFLD
                     EAVAEIARGVPEVPAPAFEPDPAGWERARTALSDAVLASATPERRDRLFPGDVEQFGGA
                     SLGIAHGAAGVLYTLDATGAGRYPDHEEWLAERAADPPRGTGLGLYDGLQGAAYVLARL
                     GHLDAALGAVGHCLNERWERLGDDLYGGLPGYALVLSHLADLTGDTSLEDAARRAVEIV
                     ANRPPQETSPRPGLMYGGAGTALMFVRWYERTGDKALLDLAETALRRDLAACVTDGNGA
                     LHVDQGHRVLPYLGRGSVGIGLVVDDYLRHRPDDPEFHEVRGSVRLAAMSRYYAQPGLF
                     NGRAGMLLYLAGQDRDDPCVARHVRDLAWHALPYAGGLAMPGEHMYRLSNDLATGTAGA
                     LLALGAALHEAPVGLPFLGTALVPPVETSTAATSIQPERR"
     misc_feature    complement(12566..12583)
                     /note="TFBS match to HipB, Bacterial antitoxin HipB,
                     confidence: weak, score: 19.59"
                     /tool="antismash"
     misc_feature    complement(12601..12617)
                     /note="TFBS match to HexR, Glucose-responsive regulator,
                     confidence: weak, score: 17.04"
                     /tool="antismash"
     misc_feature    complement(12604..12613)
                     /note="TFBS match to ToxT, Regulator of MSHA biosynthesis,
                     confidence: weak, score: 13.29"
                     /tool="antismash"
     gene            complement(12757..13605)
                     /locus_tag="K2F47_RS22700"
     CDS             complement(12757..13605)
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020540349.1"
                     /locus_tag="K2F47_RS22700"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="nitroreductase/quinone reductase family protein"
                     /protein_id="WP_242906895.1"
                     /transl_table=11
                     /translation="MTNEFNRRIIEEFRANAGRVGGPFEGGRLVLLTTTGARTGAPHTT
                     PLAYLPDAGQRVHVIASAGGSPRDPAWYRNLLADPRATVETGLFTYEARATVLDGAERD
                     AVFARAVEADPGWAEYEAAASRTLPVVALDPAFEGPPQVEGGPAAQLVRVHDAFRRELE
                     LIRAEVAASGSTVGAQLRVNCLALCEGLGNHHAGEDQMLFPALAREYPALDEALAVLRD
                     EHRVIERLLDDLRAVLAAPSPGSAALAAEVERLTTELVAHLDHEEERLVRALAQLTARA
                     N"
     gene            complement(13913..16858)
                     /locus_tag="K2F47_RS40825"
     CDS             complement(13913..16858)
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1149: LuxR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018657888.1"
                     /locus_tag="K2F47_RS40825"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="AAA family ATPase"
                     /protein_id="WP_308198442.1"
                     /transl_table=11
                     /translation="MLIGRAAQLAELTAALDRAAAGSAGVALVSGDAGVGKTHLVTALG
                     RAARDRDCAVLVGQCAELGESMPYLPLADALWTAARAAAPEAAAVRAALEARPVLGLLL
                     PDGEGAPGAASELGQQQLFGAVLGLLGELGRERPVLLVLEDLHWADRSTRHLLTFLSRV
                     LQRERVCLVGTYRSDDLHRRHPLRPVVAELLRLPNVTGVEVAPFGPGETADYLAALAGG
                     TAPVTAEVVERVHQRSEGNAFYAAELYSAESTGEELPAGLADLLLSRVERLSEDAQRVV
                     RVAAVAGRRVDDELVRRVSGLDEASAGEALREVVSHQLLVPAGAGYTFRHALLREAVYA
                     DLLPGERTRLHAGFAGLLADGAAAARRGSAAELAAHSLAAHDLPAAFAASVRAGREAER
                     LGAPAEAFEHFDRALELWDAVPDPEAVAGTDRMELSIMTARMSGRAGEVRRAVSHLRRL
                     LDLADPADTVLGVRIREQLASYLADVDEDDEALAICRTAVGMLEPGTPAWVRAAALATY
                     ARQLLYDDPDEEMPRLAEDAVAAARAAGARVAEASLLVTLGIYRESREADDAVAEVFAS
                     ARDLAAAEGNQAVALRAAFHYARTKFDRGDLAGATLAADEGVKLALDNGLEWSSFGTVL
                     RSLQYLVHYTTGDWDEAARLADGFGVRVVRPPEARVSSYALFLEVARGDPRVEERLRWL
                     VPLWRGDVFLAYVARGLAAEHELWRGNVDAAIEHVTATLDVLYQFEPGIIRIAATGLWA
                     QADRAARARAAGDEATAADAARVGDDLLGRARYVAARTWGDHPRAWLGLEGHAWLARAE
                     AERSRLDGDHDPEPWRRSADLFTYGGDGFVYEVARSRHRLVEALVERGEREEAAEQWRS
                     AVAIAERLGAAPLLAALRELGARARLDPGRPGAGRTAPGRADAAAGPFAALTVREREVL
                     KLVAEGRNNREIAAALFISPKTASVHVSNILAKLDVASRTQAAALAHREGL"
     gene            complement(17198..18466)
                     /locus_tag="K2F47_RS22715"
     CDS             complement(17198..18466)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Glycos_transf_1"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1045: glycosyl transferase group 1"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019634316.1"
                     /locus_tag="K2F47_RS22715"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="glycosyltransferase"
                     /protein_id="WP_242906897.1"
                     /sec_met_domain="Glycos_transf_1 (E-value: 9.5e-23,
                     bitscore: 76.5, seeds: 63, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MHRPLNIALVSASDLDGEHAHSVHVRDLARSLARPRPDDDDGNHV
                     TVYTRRQDPSARARTRLGPGAALVQLDAGPARPLTEAEQLDHVRDLADGLRRRWSGAGR
                     PDVVHAHGWIGGLAACAVARELGIPFFQSFHGVAATERRAGREVHPHRDRLEKAIGRGA
                     DFVLASSGEEAAAIVRSGVPRPSVKVVPYGVDADTFAPVGPAMPHGGRDRLVMVCRDLA
                     AGDVATALRALVHVPDAELAVAGGPDREDLENDPVVHRLMLLAKELHVADRVVFLGRLP
                     RKALPKLLRTARLALCLAPAQPSPAVPLEAMACGVPVVATPAGGNADEVLDKITGLHVP
                     AGRPVVIGRTVRRLLAEETTLHGYSIAAADRARSRYSWDRIAGETLRAYAKALPEPEPE
                     PVPAPRAADEAEHEADRTPAMAG"
     gene            18632..19270
                     /locus_tag="K2F47_RS22720"
     CDS             18632..19270
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019634318.1"
                     /locus_tag="K2F47_RS22720"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="histone deacetylase"
                     /protein_id="WP_242906899.1"
                     /transl_table=11
                     /translation="MENEPVWYVAYGSNLFRERFRCYLSGGRPKGGARHYPGCRDPRPA
                     RAVAPVTLPGGIYFAMESPTWGGGMAFYDPDLPGRAAARAYLLSRPQFCDVVSQEMWRD
                     TGVDVDLTEAVRAGRQRLGPGRYETVLRVGERDGRPMLTFTAPAPHGPADLNAPAAAYL
                     GMLGNGLREAHGWTAARAASYLCGRPGAAGTWRPEKVTALISGPGRPGG"
     gene            complement(19242..20888)
                     /locus_tag="K2F47_RS22725"
     CDS             complement(19242..20888)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019634324.1"
                     /locus_tag="K2F47_RS22725"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="CocE/NonD family hydrolase"
                     /protein_id="WP_308198443.1"
                     /transl_table=11
                     /translation="MVSVGMMRRLGVTALGLRNGPHRVRVERDLEVPAADGVALLADRY
                     APADVERAPVVLVRSPYGRRGPFGLMCGQAFASQGFQAVVQSVRGGFGSGGVFEPLDER
                     EDGLATIAWLREQEWFGGAFAMHGPSYLGYVQWAVAAEAGPELKALSMQVTASTFRDAV
                     NVGGAFALESALIWVDLTARMKHSLSGITTGIMSPRRARRAALSGRPLAELDRLATGAQ
                     QRFFQELLTNGADTPFWDRRDFSATVSRVDAPVNMTGGWYDIFLPWQLRDYAALRAAGH
                     RPYLTIGPWFHADQRMMRGSVGEAVKWFRAHLLDDPSQLRERPVRLFVTGAAEWREFPD
                     WPVPGMAEERWHLQPDGALAPGEPPESAPDAYRYDPRHPTPFLGGPTLLGETRPSTDQR
                     RLERRRDVLTYTSAVLEEDLEIIGPVAADLRVRSNREHTDFVVRLCDVAPDGESLNLCE
                     GMRRLMPGAPEAGADGVRRVAVELWPAGHRFRRGHRVRVQVASGAYPRVARNPGTGEPI
                     GTATAMLTADQEVLHSPAHPSAIILPVVPAR"
     gene            21014..22114
                     /locus_tag="K2F47_RS22730"
     CDS             21014..22114
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019634325.1"
                     /locus_tag="K2F47_RS22730"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="mechanosensitive ion channel family protein"
                     /protein_id="WP_242906901.1"
                     /transl_table=11
                     /translation="MRSDLGVMGDHLDWRRVLIAAIVMVAALGVAVALRMLTGRLFRRA
                     GDTRWTWDDLAARLIRDLAMPIAVLGGAWFAALVLHLPRGTLDVTARVLTAATILVVSL
                     ALARLIAGSVTSIALARQGVAANVTIFANITRVIVIGIGLLVMLQSLGVSITPLLGALG
                     VGGLAVALALQDTLANLFAGVHVLASKTIEPGDYIKLSSGQEGYVVDINWRNTSIRTLS
                     DNIEVIPNQRFSDTILTNYHRPAQDMSLLIQARVPYEADLDRVEKLVVEVGEGVMADVQ
                     GGVKDAEILVRFHTFAESSIDFTVILRTSEFGDQFAIKHEFVKRLHRRFREAGVETPYP
                     RRRVTLDEAPGADGSPVDGSPVAPGL"
ORIGIN
        1 ggcgcccagc cgttcgccga cccacgcggc ctcggcggcg gggtcgggcc agtcgatgtc
       61 gcccgtgccc atgatgacca gcgcgggcac ggtgacgcgg tcgagccggg cctcggcctc
      121 ggcgtgcgac atgctcatgt aggcgccgat gaccttggcg cggccggggc ggcggaagct
      181 cgcgtccagc ttcgccttgt gctcggcgaa gtccgcgggc ggcttcggct cccacttcgg
      241 gtagtaggac atgtagagcg ggcgcgccag ccccggcacg cgcatgaccg cctgggtgag
      301 cttctgcgcg aacccggcct cgccgtcccg gacgaacggc gccgacagga cgatcccgct
      361 gatcagcccg ggtgcctccg ccgccgcgta gacggccgcc gccgcgccgt tcgagcagcc
      421 gtgcacgagc gcgggcccgg cgtccaggtg ccggagcagc gccatcaggt cgtgggcgag
      481 gggcgtgctg ccgtactcgg gccaggcggc gtcgctgtcg cccatgccgc gctggtcgac
      541 ggtgacgacc cggtatccgg cggccagcag cagcggggtc aggaaccggt actgcgagcg
      601 caggtcgagc atggacggca ggcacacgac gagcggaccg tcgccctcgt cgtcgtaggc
      661 gaggcggccg tcgggaaggt ccaggtagtg cgtcatcgcg tgctccttcg tagctctata
      721 gctaagaaga ttagctatag agctatgcaa cgtcaagtcg tcagtcccag gcggccccga
      781 tccgccccag gtcgtcggcg tactcgatgc gcgccgccca ctcgccgggc caggcgtcca
      841 taccgaggtg cgcgcccgcg aaggcgcccg ccaggcacgc gatggagtcg gagtccccgg
      901 agctggcggc ggcgcggcgg atcgccgtga cgggctcgtc ggggaagagc aggaagcaca
      961 gcaggccggc ggcgagcgcc tcctcggcga cccagcccgc cccggtcgtc tcgcacgggt
     1021 cggccgcgcg gtccggaccg gcgagcgccg cgtccagccg gtcgagcgcg tcgatgcact
     1081 cctcccagcc gcgcgagatg aaccgccacg gatcgtccga gccggaggcg cgccacaggt
     1141 ccccgagcca ctccccgtag taggtggtgc gctcctcgta gcagcggtcg cggagcgcgt
     1201 cgggcaggtc ggcgggcgcc atgccgtcgg ccagccaccg gacggcgaac gcggtcagct
     1261 cgctcgccgc gagccccgtc gggtgcccgt gcgtcatcgc cgcctggagc tgggccgcgg
     1321 cggcgcgcgt ctcgtcggtc agccccgggg ccagcccgac cggcgcgacg cgcatgttcg
     1381 cgccgcagcc cttggagccg ggcacggtcg cctccgtcca cggcacgggc gtcgcgaggc
     1441 cgcggcaggc ggtcaggcag gtgttgcccg gcgcccggtc gttgtcgggg ctgtcgagcc
     1501 agtcgacgaa ccgccgccgc cacagcggct cgacccggtc ggcggtgaac ggcgggtcgt
     1561 ccagcgcgtc cagcagcgcg aggccgaccg cgatcgccat ctgcgtgtcg tcggtcacga
     1621 gtgccgggtc cccctcgggc cgctcgggtc cgaggtcgcc gaaccgctgc cggatctgct
     1681 ccatcgagag gaactcggtg ggcgccccga gcgcgtcccc gtacgccagc ccgaacatcg
     1741 ccccgctggc ccgtcgcgtc gtcgtcatgg gcggattgtc ccgtacctcc gcgaccgcgc
     1801 ggagcagcgg ctacggggcc cagtcgtgcg gcccgagcac gtagcccttc ggcgtcgagt
     1861 ggaggtggtt gacctcgacg aggtgcccga gcgccgccca cagctcctcc tcgggcgccg
     1921 cgaccaggcg gctcaccgtg tcgaagtccg ccgccccgcc ctccttgtcg atctccgcga
     1981 cggtctcgta gacggccagc tcgaactcgc tcagctcctg gacgtccccg cgcctgccct
     2041 ctcgctcatc catgaccgca ccctgcccac tggacgcggg tctagccgta ccggcgcgtc
     2101 cggagcgggg ccttagggtg gcggcggaag gcgccacacc gaacacgccg agatcgtctc
     2161 gtccggcccg gacgaggagg gggagttgac cacatgacct ggttccgctg cgccgagccc
     2221 cggccgtggg cgtcgacgcg gctgttctgc ctgccgcacg cgggcgggtc ggcggtgtcc
     2281 taccggtcct gggcgaagga ggccgacccg tcggtcgagg tgcacgccgt ccagtacccg
     2341 ggacgcgccg accggctggc cgagccgctc gtcggcgacg cgcacgagct ggcccggctc
     2401 gtcgcggacg cgatggtccc gctgctcgac cggcccgccg cgctgttcgg gcacagcatg
     2461 ggcgccgtcg tcgcctacga ggtcgcgcgg ctgctccagg agcgcgggag cgcgcccgtc
     2521 cacctgttcg cctccggggc ccggccgccg cacgaccggg acgacgaccg cgtctccgag
     2581 cgcgacgacg agggcgtggt cgccgagatg gtgaagctcg gcggcaccga ggccgagatt
     2641 ttggccgacc cggagctgcg ccagctggtg ctgccctacg tccgcaacga cttcgcgctg
     2701 gtcgagaact acgcgcaccg gccggggacg cggctggacg tcccggtcac cgtgatcgtc
     2761 gggaacgacg acccgcacgt gacgccggcg caggccgagc ggtgggccga gctgaccggc
     2821 gggcccttcg cgatgacggt gatggagggc ggccacttct acctcacgcc gcaccagtcc
     2881 gccgtgatcg ccgagatcca ccgcgcgctg ggcgtcgcgg cctgaccccg cccgcacgcg
     2941 ggcgggcccc cggcccccgc cggacgaggc gggggaccgg gggcccgtcc cggcacggag
     3001 gccggatggc cgtctgggga cgagaggtcg ctacacctgc cgtcagtaca cctgccgtca
     3061 gtagacttgg gcgctgtaca cctggagcgg ctcggtgacc ggctggaagt acgtcgtgcc
     3121 gccgctggag cagttgccgc tgccgcccga ggtcagcccc agcgcggtgg ccccggcgaa
     3181 cagcgagccg ccgctgtcgc ccggctccgc gcacaccgtc gtcttgatca ggccggtgac
     3241 gctgccctcc tggtagttca ccgtctggtt gagcccggtg acccggccgc tgtgcacgtg
     3301 ggtggtgctg ccgctgcgct gcacggtctg cccgacggtc ggggtcccgg cgctcgtgat
     3361 gtcctgggtg ccgccgtaga ggctgacgga gccctgggtg tcctccgggg cggaggagta
     3421 cttcacgatg ccgtagtcgt tgcccgggaa gctgccgttc tcggtgttgc cgagcagttt
     3481 ggtgtggccc tggtcggagt accaggccgt gccgatgttc gtgcagtgcc cggcggtgag
     3541 gaagtagtac tcgccgccct tcttgacgtt gaagccgagc gagcagcgtc cgccgctggt
     3601 ccagatggcc tcgccgcccc tggtgaacgg gcggagcgtc ccggcgatcc gctcggtgcg
     3661 gacggcggcg ccctgcttcg cgaccgcctt gcgcaccttg gcgagcctgc tgccggtgac
     3721 cgtgctgtcc agggacagca ggaccgtgtt gctggccggg tccacggccc acgcggtgcc
     3781 ggggacggtc gcgtcgcgct tgagcgcggc catgaccttc ttcaggtccg agccgctgcg
     3841 cgcgacggtc ttcggctggg cgcccgccgc gcggacggcc cgcgccgcgc tcgcgtcggt
     3901 gaccgtgacc acgagctgcc gggtggcggc gtcgatgtag gagccggcgg tgcgggagcc
     3961 gagccgctgg gccagcgttg tcgcggtcct ggcctgcgcc gcctgcgccg tcgtgagcac
     4021 actggcctgg gcggcctgtg cgggcgaggc cggcgcctgc ggggtcgcgt tcgcggcggg
     4081 ggcggcgacc agcgcggacg ccatgactcc cgtcgccgtc atcgtgacgg ccgcgccgct
     4141 gatgcgagcg tgacggatct tcactgagcc tccagggggg agcgggcaca cccgggtggt
     4201 atgccggagg tcaccgcaca tgctccgaga ccgcaaaggc ggacggaaga ctagaaagtg
     4261 cctaaacggc gaagagtgcg ttggcacaat gggtgcggat ttgtccagca ttcacgggca
     4321 agatggcccg tttaggacaa ttggtactca tcaggcatgg ggcaccgtgc ggaacgggta
     4381 ggacgttccg gcaaaatgat caggtgacgt tgctgctgac caggtccgat ctggagtccg
     4441 tgttcgatcc cgccggctgc ctcgccgcgc tgcgccgcgg attcaccgcg gggaaggccg
     4501 gcggggacgc ggcgcgccgc gtcgtggccc gcccgccggg tcccgggacc gcgacggcgt
     4561 tgctgccggg ggtggtcgag ggtatcccgg cctacacggt gaaggtcaac gccaagttcc
     4621 cgggcagccg tccggcgctg cgcggcgtgg tgtgcctgca cgacctcggc accggcgagc
     4681 tgctcgcgct gctggactcg gccaccgtca ccgcgtggcg caccgggctc gccgccgcgc
     4741 tcggcaccca cgtcctcgcc cgtccgggcg cggacgcggt cgcggtggtc ggggcggggg
     4801 cgcaggcgga gctggtgatg cgcgggctgg cggcgctgcg gccggtgcgc gggctcgccg
     4861 tccacgacct tgacccgggc cgggccgagg cgttcgccgc gcggcacggc gcccggctcg
     4921 ggctggacgc cgccgccctg acctcctacg gcgaggtgcc gggcgcgatc cgcgaggccg
     4981 tccgggacgc ggggatcgtc gtgacggcga cctgggcgcg gcgcccgatc ctggacgcgc
     5041 cggacgtccc gcccggcgcg cacgtcacct ccctaggggc ggacgagccg ggcaaggccg
     5101 agctggcgcc cgccctcctg cgggaggcgc gcgtcgtggt cgacgacgtc gggctagcgg
     5161 cggagatggg ggcgctcgcg ggcgccggtc ccgaggtgga gcgttccgcc gtggcgctcg
     5221 gggacgtgct ggccggccgg gcgcccggcc ggagggggga gaccgagcga accgtctacg
     5281 cgcccgtcgg cctgccctgg caggacctcg ccctgagctg ggcggccttt gaaatggccc
     5341 gttccaaagc ggttggacag gagttcgatt tcctgcgctg aactggccga ctgcggacag
     5401 cggactcttc cgacaaaaac acgcacggta attgttaata ttctatttcg tctttatgct
     5461 gactcaacga ttactgttga cgtcactcgg taggtccccg ctcatgagat cggtctgtcg
     5521 cgacgtgtcg aagcaagatc ctcatcgtga gccccgtgcc ccgggacccc cgactcggtc
     5581 accgcccttt acttctcata ggttgacaaa cggtgggtaa gtgcttctcg ggccacatgg
     5641 gtggcgggcc ttgggagaca gaacatgatt cggatactcc tcgccgagga ggcgcccctc
     5701 ctgcgaggcg ggctggtcgc gttcttcggc ggtgtgaagg acctggacgt cgtggccgcg
     5761 atcgattctg gtgatcatct agtgcgcatg gcgaatttac ggaggccgga cgttgcgttg
     5821 atagacgtcg cgcttccggg actggacggc ttctcggcgt cccggaggct gcgggaggag
     5881 cttcccgact gccggaccgt gctcatgtcg gggcggcacc gcaccggcga cctccggcgg
     5941 gcggtgaccg cccgggcggc ggggctcgtg ctgaaggaca cctcgcccgg cgcgctggtg
     6001 gacgcgatcc gccgggtcgc gggcgggcag cgcgtcgtgg acgccgagct ggccttcagc
     6061 gagctcgggt ccgcggtgag cccgctgacc gagcgcgaga gcgaggtgct ggagctggcc
     6121 tcacgcgggg cctcggcggc gcagatcgcc gaggacctcg tcctcacgat cgggacggtc
     6181 cgcaaccacc tctcccgcat caaccggaag atcggcgcgc ggaaccgggt tcacgcgatc
     6241 aggatcgccg aggaggccgg gtggctgtga gccgcccggc ccctcggggc ctgccgtgtc
     6301 cggcccatcg ggggcgccgg gggcgggccg atccgggtcc cccgtctccc agcggccgat
     6361 gaggtcgcgg tagagggggg agacggcggg caggtcccgg tgccgtccga cccgcgcgtg
     6421 cgtcccgtcc aggaccagga cgcggcgcgc gcgcacggcc gagctgaccc ggtgcgcgat
     6481 gacgacgagc gtgccggggc ggcgcgcgaa cgcctcctcg gcgcgggcct cggcggcggc
     6541 gtccagccgg caggcggcct cgtccagcac gatcagcggc gcgggcgcca ggtaggcgcg
     6601 gcacagggcg atgagctggc gctgcccctc ggtcagcgcc gccgggtcca cgctcgcgcc
     6661 gtagccgccg aggtcccgga cgaggccggc cagcccgagc tcgtccgccg cgcgccccac
     6721 gtcctcgtcg gaggcgtccg gcgcgaggta ggtcaggttc tcgtggacgg tgccggtgaa
     6781 cacgtacgcc tcctgcggga tcagcacccg cgcggacggg tcgcccgccg gacgcccgtc
     6841 caccagcacc tcgccctcca gcggcgccag caggcccgcg acgagcgccg ccagcgtcga
     6901 cttcccgatg ccgctcggcc cgacgaccgc gaggtggtcg ccgcgcggga tcacgaggtc
     6961 gaggccgctg atcaccggcc gtgccgaggg cccgtaggcg aaggtgacgc cgcgcagctc
     7021 gaccgccggc gcgtcgtcgc gccgctcgcg cggcgcgccg gtcacgggcg gcaggggcgg
     7081 cgggacgggg gcgctggtct ccaggatccg gccgagcgtc accgcgagcc gcaggccgct
     7141 gccgcccatg ccctggacga gcgtccgcag cgcgggctgc aacccgtgca ggacgtaggc
     7201 gagcgcgccg accaccatgc ccggggtcgc gccgcgccgc atcagccacg gcgccgccgc
     7261 gaggacggcc agcagcggca gccagccgct caccgcgagc gccagggccc ggaccgccgc
     7321 gaaccgcgcg accgcccgtc ccgccgccgc ctgcgcgtcg accgccgccg cgagccgctc
     7381 gcgcacctgg tcctcggcgc cgcacgcgac gacgtcccgc agcccctcgg cgagcgcggt
     7441 ggtccgctcg gcgatctcct cctcgccgac gacgaggtcg cgctgccgga cggccgccgc
     7501 cccgaacgcg gcgccgaaca gcgccagccc cgccacgagc ggcggcagca ccagcagcgc
     7561 cacctcgggc atcagcgcga gcaggccgag cagcgcggcg cccgccgcga acacgaaccc
     7621 gcgcgcgacg acgaggatgc cgccgaaggt gtcccggacg atctccacct ggtgcgtgag
     7681 ccgcgcgacc gcgccggtgt cggcccggcc gcgcagcgac cggtacagcg cgccccgggt
     7741 gacctggcgg accaggtcgt cgcggaacgg ctcgacgagc gcggcgagcg ccgggtagag
     7801 gcggcggctc ccgaaggcgc ccgcgatcgc cgcgaccgcc agcgccgcga gccaggccac
     7861 ggcgcgcacc gggcggtcgc ccacgaacgc gtcggtggcc tgcgccacgg cccgtccgaa
     7921 cacggcggtg ggcacggcct ccagcagcga ccaggcgatg acggcggacg cggcgcgcgg
     7981 ccgcccccgg acggcgcccg ccgccgtccg ccacagcagc cgcgcggcct cgcgcctcga
     8041 cgtcatgact cgcgcccgga ggtcatgatc ccgccgctcc ggcgggctcg gccaccccga
     8101 acaccgcccg gtaggacggg tcgcgccaca gctcggcgtg cgtcccgcgg ccgcggaccc
     8161 ggccgcggtc gagccagacc acgaggtcgg cgcgggcggc ggtgcccgcg cggtgcgcga
     8221 tgatcagccg ggtccggtcg ccgaaccggt ccagcacggc gccggtgacc tgtacctcgg
     8281 tcacggtgtc gaggctggag gtcgcgtcgt ccaggacgag gacgcggccc gcgtgcgcga
     8341 acgcgcgggc gaggcccatg cgctggagtt cgccgcccga catcggcgcg tccgcgagcg
     8401 gcgtcgcgta gccgtgcggg aggcggcgga cgaagtcctc ggcgcacgcc gtgcgcgccg
     8461 actcccgcag ccacgtctcg ggcgggcggc acggcccgaa cgcgatcgcg tccaggaccg
     8521 tctcgccgaa cagcgacggg cgcgcgaagg cgtatccgac gtggcggcgc agctcggcgc
     8581 gggacaggcg ggggagcggc gccccgtcca gcagcacctc gccccggtcg gggtcggcga
     8641 ggcgcccggc gagcgcggcg agcagcgact tgcccgcgcc cgagcggccg acgaccgcga
     8701 ccgcgaggcc gccggggacg gtgaggtcca cgccgtccag cacgccgccc gccgacacgc
     8761 cgcggaactc cagcgtgccc ggcccctgcg ggacggcggc gtcgccgtgg acgggggcgg
     8821 gctgctccag gatctcggcg gcgcggcggg ccccggcgcg cgcccggccg agccgcagca
     8881 catgggtgag gacgggcccg aacccggccg cgagccccgc gtactgcacg gtcgcgacga
     8941 gttcgccggg ggtgacgcgg cccgccatca gctccgcgcc cgccgcgccg acggcggcga
     9001 cctggagcag cagcagggtc agcaggccgc gcgccgcgac gccgccctgc accgaccaca
     9061 tcgtctcgcc ctcggcgcgc aggccgggca gcggccgcag gatgcgctcg gtctcccgct
     9121 cggcggtgcc ggcggcggcg atcgtgcggg ccccggcgag cgcctcggcg aggcgtccgg
     9181 cgatcgtccc ctgcacgctc aggtagcggt gcgcggacgc ggtgatgtcg cggacgaaca
     9241 cccgcagcag cagcacgatc gcgggcagcg cgaccgcgac ggcgaccgcg agccgccagt
     9301 cgaggaacgc cagcacggcg agcgcgccga gcggcggcag cagcgcgacg gcggcctcgg
     9361 gcgcggcggc gggcgcggtg ccggcctcgg cggcgccgcc gaccgtgcgc ccggcgacgt
     9421 ccccgggcgg gacgcgcagc gccgggccga cggcgaggac gtgccggacg agcgcgtgcc
     9481 gcagccaggc cgtcgcccgc gcggccgcgc atccggtcgc gagttccgag agcacctctg
     9541 cggtggccga caggagcacg agcgcgacgc acggccacag cgccgacacg gcggacgcgc
     9601 cgcccggcgg ggcggcgtcg acggcgcggg cgagcgcgag ggggagcagg acggcggcga
     9661 gggcgtcggc gagcgcggtg gccgcgacga gcccggtcca gccgccgctg tgccgcgcgg
     9721 cgccgaccag cagccggtcc gctccggcgg ccgtcggggt ggtcatgggt tcggagaggt
     9781 cgtggggttg ttcgaggcct gagggtcgtt cgagggcatg gttctcccgc gatgacggcc
     9841 atggtccctc ccagggggag ggccatggcc gccaccgttg ccgttacagg cagatggtga
     9901 tgctgtgcga gctgtggcag agcaggctga ggctgctgtt accgccgccg ccgccgttct
     9961 cgctcaccat tccctgaagg tcaagaagcg ccatttgtct tcacctcctt tcgggctgga
    10021 tagaggtggc cgccgtggag gtctccacgg ggggtacgag ggccgtcccg aggaacggca
    10081 gtccgaccgg agcctcgtgc agcgccgcgc cgagggcgag cagcgccccg gccgtgccgg
    10141 tcgcgaggtc gttcgacagc cggtacatgt gctcgccggg catcgccagc ccgcccgcgt
    10201 agggcagcgc gtgccaggcg aggtcgcgga cgtggcgcgc gacgcacggg tcgtcgcggt
    10261 cctggcccgc caggtagagg agcattccgg cgcggccgtt gaacaggccg ggttgcgcgt
    10321 agtaccgcga catcgccgcc agccggaccg aaccgcggac ttcgtggaac tccgggtcgt
    10381 ccgggcggtg ccggaggtag tcgtccacga ccaggccgat gccgacgctg ccgcgcccga
    10441 ggtagggcag cacgcggtgg ccctggtcga cgtgcagggc gccgttgccg tcggtgacgc
    10501 acgcggcgag gtcgcggcgc agggcggtct cggcgaggtc cagcagcgcc ttgtcgcccg
    10561 tcctctcgta ccagcggacg aacatcagcg ccgtcccggc cccgccgtac atcagcccgg
    10621 ggcgggggct cgtctcctgc ggggggcggt tcgcgacgat ctcgacggcg cggcgcgccg
    10681 cgtcctccag ggacgtgtcg cccgtgaggt ccgcgaggtg ggacagcacc agcgcgtacc
    10741 cggggagccc gccgtagagg tcgtcgccga ggcgctccca ccgctcgttc aggcagtgcc
    10801 cgaccgcgcc gagcgccgcg tcgaggtgcc cgagccgcgc gaggacgtac gcggcgccct
    10861 gcaacccgtc gtagaggccg aggccggtgc cgcgcggtgg atcggcggcc cgctcggcga
    10921 gccactcctc gtggtcgggg taccggccgg cgccggtcgc gtccagcgtg tacaggacgc
    10981 ccgccgcgcc gtgggcgatg ccgagcgacg cgcccccgaa ctgctccacg tcaccgggga
    11041 acagccggtc gcggcgctcg ggggtggcgc tggcgaggac ggcgtccgac agggcggtgc
    11101 gggcgcgctc ccaaccggcc gggtcaggct cgaaggcggg cgccgggacc tcggggacgc
    11161 cgcgcgcgat ctccgcgacg gcctcgtcga ggaacgggcg cggcaccggg aagtactcgg
    11221 cgatcaggtc ggccagctgc cgcgccttgc cccggtcgat cacgaacagc gtcgtcatcg
    11281 ggacgaacag cgcgagccgc aggcacgcca ggctgtagcg gtcgacctcc gtgccgcgcc
    11341 ggtcgggcgg ggcgaggaag gccgggttgg cgagcgtctg ccggccgccg tcggcggcgg
    11401 gcgcggcgac ctcgaagtcg atgagcgcga ccgagtcgtc cgggcggacc atcacgttga
    11461 acatgtgcag gtcgttgaag gcgacgccgc gctcgtggat cgcgtccacc acccgctcga
    11521 cgccctcgtg gacgcgcagc gcccacgccg tgtacgcggc gaccttgccg ggctccggct
    11581 cggggtcgag catcgggtgg cgctcggcga agaaggtgtt gagcgtccgc ccctcgatga
    11641 actcctggac gaggaaatgg tgctcgccga gcgtgaagga atcgcgcgcg gcgggaattc
    11701 cgtcgatccc gtccagcagt tcgagaatgc ggcgctctcg gtcgaggcgt tcgaccgcgt
    11761 cggcgccgtc ggcggcgagc ccggcgtagg ggcgcgcctc cttcagcacg accttctctc
    11821 cggtacgcgt gtccgttccc tggtacacgc cgccgccgtt ggagaagtgc agcgccttct
    11881 cgatccggta cggaagatcg gtcgtcgtgg tggcgccccg cgcggcgaga tgcggttcga
    11941 ggcagcgggg cagcgtcacc cattccggga cggagaagac ggggttgcgg cggtcgggga
    12001 ccagcacgcc ctcgccgttc tccagcgcgg cgacgagctc gccgcgctcg tccaggcagc
    12061 ggcgctcggc gaaaccgccg tagcggacgt acagggggcc gtcgccgatg cgcaggtcac
    12121 tgaggatgta gggcccgggc aggccggcga gccgggcgcc gagcgtctcc agcaccgact
    12181 ccagctccgc ctcgtcgctc gggtagatgg tgacgagctt gccgctcgcc ccgcgcggcg
    12241 cgtacttggc gttgcgcatc cggagcgtcc cggggccgtg caggtgcttg aactcgatgc
    12301 cgttctcgac gcagaagtcg aaggagccgg cgagcgcctc gtccgcgctt tccgcgcagc
    12361 cggtgacgtg caccttccag ccctggagcg gagccttctg ctccggcggg acgtacaccg
    12421 tccattcttc tccgcgcacc ctttcccaac cttccggaag ggggcgggcg gcgatgtcga
    12481 attcggtttc acgggacgtc ggaggggcgt cgtagaagaa cttgtccgcg aggcagtaaa
    12541 gctcatacct cttgtccacg acgtcaatcc tctctgccgg atccggcggg cgccggtcac
    12601 aggtaaaaga atggcaaatg gcggagaagg gggctagtag ctgatataac gactcacccg
    12661 tgaagatgta ccggccgcgc gtgggcgttc gtcaccctcc gcccgcgtcc cgtgaccgtg
    12721 cgcccgccct gacctggtgt tacgcagtgc tcgctgtcag ttggcgcgcg ctgtcagttg
    12781 ggcgagcgcc cgcaccagcc gctcctcctc gtggtccagg tgcgcgacga gctcggtcgt
    12841 cagccgctcg acctccgccg cgagggcggc ggagccgggg gagggcgcgg cgaggacggc
    12901 ccgcaggtcg tccaggagcc gctcgatcac ccggtgctcg tcgcggagca cggccagggc
    12961 ctcgtccagg gccgggtact ccctcgccag ggccgggaag agcatctggt cctccccggc
    13021 gtggtggttg ccgagcccct cgcacagcgc gaggcagttg acgcgcagct gcgcgccgac
    13081 cgtggacccg gacgcggcga cctccgcccg gatcagctcc agctcgcggc ggaacgcgtc
    13141 gtggacgcgg acgagctggg ccgccgggcc gccctcgacc tgcggcgggc cctcgaaggc
    13201 cgggtcgagc gcgacgaccg gcagcgtccg ggacgcggcc gcctcgtact ccgcccaccc
    13261 cggatcggcc tcgacggccc gcgcgaacac cgcgtcccgc tcggcgccgt ccagcaccgt
    13321 ggcccgcgcc tcgtaggtga acaggcccgt ctcgacggtg gcgcgggggt cggccagcag
    13381 gttgcggtac caggccgggt cccgtgggga gccgcccgcc gaggcgatga cgtggacgcg
    13441 ctgcccggcg tccgggaggt aggcgagcgg cgtggtgtgc ggggcgccgg tccgcgcgcc
    13501 ggtggtggtc agcaggacga gccggccgcc ctcgaacggg ccgcccaccc gtccggcgtt
    13561 cgcgcggaac tcctcgatga tccgccggtt gaattcgttc gtcattccgg tgcttctcct
    13621 tttcggggca tgctgaattc gccacgggag ggtgctcgac cgcggcgtac ggaaggaaag
    13681 cgtgaagaac ggcatgcgga aagcacgccg aagcccggtg cgcgcacggg cgtgcggcat
    13741 cgaggtaaag ggggagaggg ggcgcgaggt gcgcggatgc cggcggaggc ggggccctgg
    13801 ccccggcgct cacgtcgcgg ccgggtgcct cactcggtag tggcccatgg ccgacccggc
    13861 agtcacggaa ttgatcctaa agggcatcgc attgccgtgg caagggcggc cgctaaagcc
    13921 cttcgcggtg cgcgagcgcg gcggcctggg tgcggctcgc gacgtccagc ttggcgagga
    13981 tgttcgacac gtgcacgctc gcggtcttcg gggagatgaa cagcgccgcc gcgatctccc
    14041 ggttgttgcg gccctccgcg acgagcttga gcacctcccg ctcccggacg gtcagcgccg
    14101 cgaacggccc ggccgcggcg tccgcccgcc ccggcgccgt ccgccccgct cccggccgtc
    14161 ccgggtcgag ccgggcgcgg gcgccgagtt cgcgcagcgc cgccagcagc ggggccgcgc
    14221 cgagccgctc ggcgatcgcg acggccgacc gccactgctc ggcggcctcc tcgcgctcgc
    14281 cgcgctcgac gagcgcctcc accagccggt gccgcgaccg cgcgacctcg tagacgaagc
    14341 cgtccccgcc gtaggtgaac aggtcggcgg acctgcgcca cggctcgggg tcgtggtcac
    14401 cgtccaggcg gctgcgctcg gcctcggcgc gggcgagcca ggcgtgcccc tccagcccga
    14461 gccacgcgcg gggatggtcg ccccaggtgc gggctgcgac gtaccgggcg cggcccagca
    14521 ggtcgtcgcc cacgcgcgcg gcgtcggcgg cggtggcctc gtcgcccgcc gcgcgggccc
    14581 gcgcggcgcg gtcggcctgc gcccacaggc cggtcgcggc gatgcggatg atgcccggct
    14641 cgaactggta caggacgtcc agcgtggccg tcacgtgctc gatcgccgcg tccacgttcc
    14701 cgcgccacag ctcgtgctcg gcggcgagcc cgcgcgcgac gtaggcgagg aagacgtccc
    14761 cgcgccacag cgggaccagc cagcgcagcc gctcctcgac ccgggggtcg ccgcgcgcga
    14821 cctccaggaa cagcgcgtac gacgacaccc gcgcctcggg cgggcggacg acccgcaccc
    14881 cgaacccgtc ggcgagccgg gccgcctcgt cccagtcccc ggtggtgtag tggacgaggt
    14941 actggaggct gcggagcacc gtcccgaacg agctccactc caggccgttg tcgagggcga
    15001 gcttgacgcc ctcgtcggcg gcgagcgtcg cgcccgcgag gtcgccgcgg tcgaacttcg
    15061 tgcgggcgta gtggaacgcg gcccgcagcg cgaccgcctg gttgccctcg gcggcggcga
    15121 ggtcgcgggc ggacgcgaac acctcggcga ccgcgtcgtc ggcctcccgc gactcgcggt
    15181 agatgccgag cgtgaccagc aggctcgcct ccgcgacgcg cgcgccggcc gcgcgcgccg
    15241 ccgcgacggc gtcctcggcg agccggggca tctcctcgtc cgggtcgtcg tagagcagct
    15301 gccgggcgta ggtggcgagc gcggcggcgc gcacccacgc cggggtgccg ggttcgagca
    15361 tgccgacggc ggtgcggcag atcgcgaggg cctcgtcgtc ctcgtcgacg tcggcgaggt
    15421 aggaggcgag ctgctcgcgg atccgcacgc cgagcacggt gtccgcgggg tcggcgaggt
    15481 cgagcagccg ccgcaggtgc gagacggccc ggcgcacctc gcccgcccgt cccgacatcc
    15541 gggcggtcat gatcgacagt tccatccggt cggtgccggc gacggcctcg gggtcgggga
    15601 cggcgtccca cagctccagc gcccggtcga agtgctcgaa cgcctcggcg ggcgcgccga
    15661 gccgctcggc ctcgcggccc gcccggacgg acgcggcgaa cgcggcgggc aggtcgtgcg
    15721 cggcgaggct gtgcgccgcc agctcggccg ccgacccgcg ccgggcggcg gccgccccgt
    15781 ccgccagcag cccggcgaac cccgcgtgca gccgggtccg ctcgccgggc agcaggtcgg
    15841 cgtagacggc ctcgcgcagc agcgcgtgcc ggaacgtgta gcccgcgccc gccgggacga
    15901 gcagctggtg cgagacgacc tcccgcagcg cctccccggc ggacgcctcg tccagccccg
    15961 acacccggcg gaccagctcg tcgtcgaccc gccgcccggc gacggccgcg acccgcacga
    16021 cgcgctgcgc gtcctccgag agccgctcca cccgcgacag cagcaggtcg gcgagcccgg
    16081 cgggcagctc ctcgccggtg ctctcggccg agtacagctc ggcggcgtag aaggcgttgc
    16141 cctccgagcg ctggtgcacc cgctcgacga cctcggcggt caccggcgcc gtcccgcccg
    16201 cgagcgcggc gaggtagtcg gcggtctccc cgggcccgaa cggcgcgacc tcgaccccgg
    16261 tcacgttcgg cagccgcagc agctccgcca cgaccgggcg cagcgggtgc cgccggtgca
    16321 ggtcgtcgga gcggtaggtg ccgacgaggc agacccgctc gcgctggagg acgcggctca
    16381 ggaacgtcag caggtgccgg gtcgagcggt cggcccagtg caggtcctcc agcaccagca
    16441 ggacgggccg ctcccggccg agctcgccga gcagcccgag gaccgcgccg aacagctgct
    16501 gctgcccgag ctcggacgcg gcgcccggcg ccccctcgcc gtccggcaac agcagcccga
    16561 gcacgggacg cgcctccagc gcggcgcgca cggcggcggc ctccggggcg gcggcgcgcg
    16621 cggcggtcca cagcgcgtcc gcgagcggca ggtagggcat gctctcgccc agctcggcgc
    16681 actgcccgac gaggacggcg cagtcgcggt cgcgggcggc gcggccgagc gcggtgacga
    16741 ggtgggtctt gccgaccccg gcgtccccgc tgacgagcgc gaccccggcg ctgcccgcgg
    16801 cggcgcggtc gagcgcggcg gtcagctcgg cgagctgcgc cgccctcccg atcagcaccc
    16861 ggcgcccccg gacgtcgcgt attcggccat gtcgcacagt atcccaccgg ccggaacacc
    16921 gagaaacgcc ccgcgccgcc cgaacccgag cggcggcccc cgaccatgcg ctgcctcgac
    16981 gcgtgcggtg ccgggccgtg cgcggcgctg ggacggcagg ggtgtccggg tacgccgcgc
    17041 ggcgtacccg gacacagcgg tgcctgaacc cgccgtgcgg tgccctcccg cagcggtgcc
    17101 ggaacaccgg cggtgtccgg ggaccgccgt gcgggggcgg acatgagcgg gccccggatc
    17161 cggggaggga tccggggccc gccggtgacg gggcgcgtca gccggccatg gcgggtgtcc
    17221 ggtcggcctc gtgctccgcc tcgtccgcgg cccggggcgc gggcaccggc tcgggctcgg
    17281 gctcgggcag cgccttggcg taggcgcgca gggtctcgcc cgcgatccgg tcccaggagt
    17341 agcgggagcg ggcgcggtcg gcggcggcga tggagtagcc gtgcagggtg gtctcctcgg
    17401 cgagcaggcg ccggaccgtc cggccgatca cgaccggccg cccggccggg acgtgcaggc
    17461 cggtgatctt gtcgagcacc tcgtcggcgt tgccgcccgc gggcgtcgcg acgaccggca
    17521 cgccgcaggc catggcctcc agcggcaccg ccggggacgg ctgggcgggc gcgaggcaca
    17581 gcgccagccg ggcggtgcgc agcagcttgg gcagggcctt gcgagggagg cggccgagga
    17641 acaccacgcg gtcggcgacg tgcagctcct tggcgagcag catcagccgg tggacgaccg
    17701 ggtcgttctc caggtcctcc cggtccgggc cgccggcgac ggccagctcg gcgtcgggga
    17761 cgtggacgag ggcgcgcagc gcggtcgcga cgtcgccggc cgcgaggtcg cggcacacca
    17821 tcacgaggcg gtcccggccg ccgtgcggca tcgccgggcc gaccggcgcg aacgtgtcgg
    17881 cgtccacgcc gtaggggacg accttgaccg acggccgggg cacgccggag cggacgatcg
    17941 cggcggcctc ctcgccgctg gaggccagta cgaagtcggc gccgcggccg atggccttct
    18001 ccagccggtc gcggtgcggg tgcacctcgc ggccggcgcg ccgctcggtg gcggcgaccc
    18061 cgtggaagct ctggaagaag gggatgccga gctcgcgggc gacggcgcag gcggccaggc
    18121 cgccgatcca gccgtgcgcg tgcacgacgt cgggccgccc cgccccgctc caccggcggc
    18181 gcaggccgtc ggcgaggtcg cggacgtggt cgagctgctc ggcctcggtg aggggccgcg
    18241 cggggcccgc gtcgagctgg acgagcgcgg cgccggggcc gagcctggtc cgggcgcggg
    18301 cggacgggtc ctgccgccgg gtgtacacgg tgacgtggtt gccgtcgtcg tcatccggac
    18361 ggggccgggc gagcgagcgg gcgagatccc ggacgtggac ggaatgcgcg tgttcgccgt
    18421 cgaggtcgga ggcggacacg agcgcgatgt tcagcgggcg atgcatgacg atcctccggg
    18481 acaacacagg ggaagcctgg aggtatctgc gtcgtagaca cctgctcgca ggagactatt
    18541 tccgtgtgcc caccccgtca aacctcgcga atcggatcac cccggggccc agggccgccg
    18601 cgaagccctg accggcgggg atactgagga tatggagaat gaaccggtct ggtacgtggc
    18661 ctacggatcg aacctcttcc gcgagaggtt ccgctgctac ctgtccggtg gacggccgaa
    18721 gggcggcgcc cggcactacc cgggctgccg cgacccgcgt ccggcgcgcg cggtggcgcc
    18781 ggtcacactg ccgggcggca tctacttcgc catggaatcg ccgacgtggg gcggcggcat
    18841 ggccttctac gacccggacc tgccgggacg cgccgccgcc cgcgcctacc tgctctcgcg
    18901 gccgcagttc tgcgacgtgg tctcgcagga gatgtggcgc gacaccggcg tggacgtcga
    18961 cctgacggag gcggtgcgcg cgggccgcca gcggctcggc cccggccgct acgagaccgt
    19021 cctgcgggtc ggcgagcgcg acggccgccc catgctcacc ttcaccgcgc ccgccccgca
    19081 cggccccgcc gacctgaacg cgccggccgc cgcgtacctg ggcatgctcg gcaacgggct
    19141 gcgcgaggcg cacggctgga cggccgcgcg cgccgcgtcc tacctgtgcg ggcggccagg
    19201 cgcggcgggg acgtggcgtc cggagaaggt gaccgcgctg atcagcgggc cgggacgacc
    19261 gggaggatga tcgccgacgg gtgcgcgggg gagtgcagca cctcctggtc ggcggtgagc
    19321 atggcggtgg cggtgccgat cggctcgccg gtgccggggt tgcgcgcgac gcgcgggtag
    19381 gcgccgctcg cgacctgcac gcgcacccgg tgcccgcgcc ggaagcggtg cccggcgggc
    19441 cacagctcga cggcgacgcg gcggacgccg tccgcgcccg cctcgggggc gccgggcatg
    19501 agccgccgca tcccctcgca caggttcagc gactcgccgt ccggcgccac gtcgcacagc
    19561 cggacgacga agtcggtgtg ctcccggttc gagcggaccc gcaggtcggc ggcgaccggg
    19621 ccgatgatct ccaggtcctc ctccagcacg gcggaggtgt aggtcagcac gtcgcggcgg
    19681 cgctccaggc gccgctggtc ggtggacggg cgggtctcgc cgagcagcgt gggcccgccg
    19741 aggaacggcg tcgggtgccg ggggtcgtag cggtaggcgt ccggggcgga ctcgggcggc
    19801 tccccggggg cgagcgcccc gtccggctgg aggtgccagc gctcctcggc catccccggg
    19861 acgggccagt cggggaactc gcgccactcc gccgcgccgg tcacgaacag ccggacgggc
    19921 cgctcccgca gctgcgacgg gtcgtccagc aggtgcgcgc ggaaccactt caccgcctcg
    19981 ccgaccgagc cgcgcatcat ccgctggtcg gcgtggaacc agggcccgat cgtcaggtag
    20041 gggcggtgcc cggcggcgcg cagcgcggcg tagtcgcgca actgccaggg caggaagatg
    20101 tcgtaccagc cgccggtcat gttgaccggc gcgtccaccc gggacacggt ggcgctgaag
    20161 tcgcgccggt cccagaacgg ggtgtcggcg ccgttggtga gcagctcctg gaagaaccgc
    20221 tgctgcgcgc cggtcgcgag ccggtccagc tcggcgagcg ggcggcccga cagcgcggcc
    20281 cgccgggcgc ggcgcggcga catgatcccg gtggtgatgc ccgacagcga gtgcttcatc
    20341 cgggccgtca ggtcgaccca gatcagcgcc gactccagcg cgaacgcgcc gccgacgttc
    20401 accgcgtccc ggaacgtgga cgccgtgacc tgcatcgaca gcgccttcag ttccggcccg
    20461 gcctcggcgg cgacggccca ctgcacgtag ccgaggtagc tcgggccgtg catcgcgaac
    20521 gcgccgccga accactcctg ctcccggagc cacgcgatgg tggcgaggcc gtcctcccgc
    20581 tcgtccagcg gctcgaacac cccgcccgag ccgaagccgc cgcgcacgct ctgcaccacg
    20641 gcctggaacc cctgcgacgc gaacgcctgc ccgcacatga gcccgaacgg cccgcgccgg
    20701 ccgtaggggg agcggacgag caccaccggc gcccgctcca cgtcggcggg cgcgtaccgg
    20761 tcggccagca gggcgacgcc gtcggcggcg ggcacctcca ggtcgcgctc gacccgtacc
    20821 cggtgggggc cgttccgcag tcccagcgcc gtgaccccga gccggcgcat catcccgacg
    20881 ctcaccactt gatcgatcgt aacccgcggc tccccgcgcc gctcgggcgg cctcaccccg
    20941 caccgggtcc cggccgctcc ggtccttcac tacgatcgtg ggcgaaatcc ggatctgccc
    21001 ggcaagtcga ccattgagga gtgatctggg cgtcatgggc gaccacctgg actggcggcg
    21061 ggtcctcatc gcggcgatcg tcatggtggc cgcgctgggg gtcgcggtgg cgctgcggat
    21121 gctcaccgga cggctgttcc gccgcgccgg ggacacccgg tggacgtggg acgacctcgc
    21181 ggcccggctg atccgcgacc tcgcgatgcc gatcgcggtg ctcggcggcg cctggttcgc
    21241 ggcgctggtc ctgcacctgc cgcgcggcac gctggacgtc accgcccggg tgctgaccgc
    21301 cgcgacgatc ctcgtggtgt cgctggcgct ggcgcggctc atcgccgggt cggtcacctc
    21361 gatcgcgctg gcccggcagg gcgtggccgc caacgtgacg atcttcgcca acatcacccg
    21421 cgtgatcgtc atcggcatcg gcctgctggt catgctccag agcctcggcg tgtcgatcac
    21481 accgctgctc ggcgccctcg gcgtcggcgg cctcgcggtc gcgctcgcct tgcaggacac
    21541 gctcgccaac ctgttcgcgg gcgtgcacgt gctggcgtcc aagaccatcg agcccggcga
    21601 ctacatcaag ctgagcagcg ggcaggaggg gtacgtcgtc gacatcaact ggcgcaacac
    21661 ctccatccgc acgctgtcgg acaacatcga ggtcatcccg aaccagcggt tctccgacac
    21721 gatcctcacc aactaccacc ggcccgcgca ggacatgtcg ctgctgatcc aggcgcgcgt
    21781 cccctacgag gccgacctgg accgggtcga gaagctcgtc gtcgaggtcg gcgagggcgt
    21841 gatggcggac gtgcagggcg gcgtgaagga cgcggagatc ctcgtccgct tccacacctt
    21901 cgccgagtcg tccatcgact tcaccgtcat cctgcgcacc agcgagttcg gcgaccagtt
    21961 cgccatcaag cacgagttcg tcaagcggct gcaccgcagg ttccgtgagg cgggcgtcga
    22021 gacgccctac ccgcgccgcc gcgtgacgct ggacgaggcg cccggcgcgg acggcagccc
    22081 cgtggacggc agccccgtgg cgcccggcct gtagagccgt gacgcccccg acgggtcagg
    22141 ggcgcagcat cgggagcagg atgtcgtcga ccagctcggc gagctgcgcg tcgtccatcg
    22201 tgccgccctc ggtgaggtgg tcgtacacga tcagcgccgg gccgacgttc gcgaccttcc
    22261 gggtgaccgc cgccggacgg acctcgccgc gcgccgcgcc ctgctccagg gcctcgtaca
    22321 gcgcctcccg cacgggctgg gagatgcgcg cgcggatcac gtcgtggatc aggcccttgc
    22381 cgtcggcgga ctcctccttc agcaccttga acgccgcgcc ccggcaggtg accagcgtgt
    22441 cgcgcaggca ggtgagcgtg gccagcaggt cccggcgcac gctcccggtc gccggacgcg
    22501 gcggcgggtt cggcagcgcg tgccgcagcg cgtcgctgac caggtcctcc ttggactgc
//
