LOCUS       NZ_JAICDG010000002     24881 bp    DNA     linear   CON 29-AUG-2024
DEFINITION  Actinomadura terrae strain OS3-83 contig2, whole genome shotgun
            sequence.
ACCESSION   NZ_JAICDG010000002
VERSION     NZ_JAICDG010000002.1
KEYWORDS    WGS; RefSeq.
SOURCE      Actinomadura terrae
  ORGANISM  Actinomadura terrae
            Bacteria; Actinomycetota; Actinomycetes; Streptosporangiales;
            Thermomonosporaceae; Actinomadura.
REFERENCE   1  (bases 1 to 2162430)
  AUTHORS   Lee,S.D., Yang,H.L., Kim,I.S., Choe,H. and Kim,J.S.
  TITLE     Actinomadura terrae sp. nov. and Actinomadura litoris OS3-89,
            isolated from rhizosphere soil of cactus
  JOURNAL   Int J Syst Evol Microbiol 73 (1) (2023)
   PUBMED   36748505
REFERENCE   2  (bases 1 to 2162430)
  AUTHORS   Lee,S.D.
  TITLE     Direct Submission
  JOURNAL   Submitted (15-FEB-2022) Institute of Jeju Microbial Resources, BioPS
            Co., Ltd., Sancheondan Dongil 16, Jeju 63243, South Korea
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: SPAdes v. 3.13.0
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 141x
            Sequencing Technology             :: Illumina
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_022751215.1-RS_2024_08_29
            Annotation Date                   :: 08/29/2024 06:12:19
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.8
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 8,085
            CDSs (total)                      :: 8,002
            Genes (coding)                    :: 7,936
            CDSs (with protein)               :: 7,936
            Genes (RNA)                       :: 83
            rRNAs                             :: 5, 4, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 3 (5S)
            partial rRNAs                     :: 2, 4, 4 (5S, 16S, 23S)
            tRNAs                             :: 67
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 66
            CDSs (without protein)            :: 66
            Pseudo Genes (ambiguous residues) :: 0 of 66
            Pseudo Genes (frameshifted)       :: 13 of 66
            Pseudo Genes (incomplete)         :: 56 of 66
            Pseudo Genes (internal stop)      :: 3 of 66
            Pseudo Genes (multiple problems)  :: 4 of 66
            CRISPR Arrays                     :: 4
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 21:31:58
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 310963
            Orig. end                         :: 335844
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            JAICDG010000002.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..24881
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene"
                     /region_number="3"
                     /rules="(PT_phytoene_like or phytoene_synt or Lycopene_cycl
                     or Lycopene_cycl_fung or T1TS or T1TS_KS or T2TS or TS_UbiA
                     or TS_Pyr4)"
                     /tool="antismash"
     cand_cluster    1..24881
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /kind="single"
                     /product="terpene"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..24881
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:14881]"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..14881
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
     gene            1611..2948
                     /gene="nuoH"
                     /locus_tag="K2F47_RS11555"
     CDS             1611..2948
                     /EC_number="1.6.5.9"
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0016651 - oxidoreductase activity, acting
                     on NAD(P)H [Evidence IEA]"
                     /GO_function="GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="nuoH"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018654731.1"
                     /locus_tag="K2F47_RS11555"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="NADH-quinone oxidoreductase subunit NuoH"
                     /protein_id="WP_242902876.1"
                     /transl_table=11
                     /translation="MSPLTLAAASAKEPTLKSFGDDPWWLIGGKVLAIFVFLVLTVLLS
                     MWVERRVIARMQLRVGPNRVGPQGLLQGLADGVKLALKEDIVPRQVDKLVFVLAPIVSA
                     VPAFISFIIIPFGPTVSVFGHQTALQGTDLPVAVLLVLAMSSMGVYGIVLAGWSSMSPY
                     SLLGGLRSSAQVISYEIAMGLSFVAVFLFAGSMSTSDIVAAQHDKWFVVLLLPSFLVYV
                     ITMMGESNRIPFDLPEGEGELVGGFHTEYSSLKFAMFFLAEYINLATLSALATTLFLGG
                     WRAPAPISTVWAGANAGWWPVLWFLVKLWLFIFFFIWLRGSLPRVRYDQLMKLGWKVLM
                     PFSLGWILLVSTIRALRNEGHDMRQIVIIAAVVAAVVLVATVIWEMLRGGEDEKEIVPG
                     AGRDAAPDPAAGGFPVPPLDLPHYHGGPAGATKVKTPPEEVTSGTH"
     gene            2992..3531
                     /gene="nuoI"
                     /locus_tag="K2F47_RS11560"
     CDS             2992..3531
                     /EC_number="1.6.5.9"
                     /GO_function="GO:0016651 - oxidoreductase activity, acting
                     on NAD(P)H [Evidence IEA]"
                     /codon_start=1
                     /gene="nuoI"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017623181.1"
                     /locus_tag="K2F47_RS11560"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="NADH-quinone oxidoreductase subunit NuoI"
                     /protein_id="WP_242905903.1"
                     /transl_table=11
                     /translation="MFSKSETVQYPEVKKPTAPRFHGRHQLNRWPDGLEKCVGCELCAW
                     ACPADAIFVEGADNTVDERYSPGERYGRIYQINYLRCILCGLCIEACPTRALTMTNEYE
                     LADDSRESLIYTKEMLLAPLREGMEQPPHEMRLGDTEEEYYRLGLQPEESAAAPAESGG
                     ASAAKRPRGRKGGDAK"
     gene            3555..4511
                     /locus_tag="K2F47_RS11565"
     CDS             3555..4511
                     /EC_number="1.6.5.9"
                     /GO_function="GO:0008137 - NADH dehydrogenase (ubiquinone)
                     activity [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017593303.1"
                     /locus_tag="K2F47_RS11565"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="NADH-quinone oxidoreductase subunit J"
                     /protein_id="WP_372490866.1"
                     /transl_table=11
                     /translation="MAGHVASGHVLAGHVADKQSGEPFFFWLLAVVSVCAALGMIFMRK
                     AVHSALLLATVMLSLAALYAIQDAPFLAFVQVIVYTGAVLMLFLFVLMLVGVSSTDSLV
                     ETIRGQRFWAAVGAIGFVVLLAIGLGNAALGDSAGLKTANGDGNVVGLARLLFKDYVFA
                     FEATSALLITAALGAMVLAHRERTEPKPTQRDLSKGRFLSGEHPGPLPGPGTYARHNAV
                     DMPALLPDGTPSELSVNPIIAARTDTVERHVDLHGETEEEALGHDVAAVRAVTGEARDA
                     GAESRVVKAGSPVAGGPSEGGAGGGTSGNEREGEAGQ"
     gene            4508..4807
                     /gene="nuoK"
                     /locus_tag="K2F47_RS11570"
     CDS             4508..4807
                     /EC_number="1.6.5.9"
                     /GO_function="GO:0016651 - oxidoreductase activity, acting
                     on NAD(P)H [Evidence IEA]"
                     /GO_process="GO:0042773 - ATP synthesis coupled electron
                     transport [Evidence IEA]"
                     /codon_start=1
                     /gene="nuoK"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019814967.1"
                     /locus_tag="K2F47_RS11570"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="NADH-quinone oxidoreductase subunit NuoK"
                     /protein_id="WP_067466785.1"
                     /transl_table=11
                     /translation="MSPGHYLALSAILFTIGALGVLVRRNAIVVFMCVELMLNATNLAF
                     VSFSRMHGELDGQIIAFFVMVVAAAEVVVGLAIIMTIFRTRRSSSVDDANLLKY"
     gene            4818..6734
                     /gene="nuoL"
                     /locus_tag="K2F47_RS11575"
     CDS             4818..6734
                     /EC_number="7.1.1.2"
                     /GO_function="GO:0008137 - NADH dehydrogenase (ubiquinone)
                     activity [Evidence IEA]"
                     /GO_process="GO:0042773 - ATP synthesis coupled electron
                     transport [Evidence IEA]"
                     /codon_start=1
                     /gene="nuoL"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018654735.1"
                     /locus_tag="K2F47_RS11575"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="NADH-quinone oxidoreductase subunit L"
                     /protein_id="WP_242902877.1"
                     /transl_table=11
                     /translation="MKAEGIQAASWLLIALPLAGAAILLLGGRRTDRWGHLLGVTMSLA
                     SFVVGAAMFVQMLGYEAEERRRTLHLWDFIDVGSFKVGMDLLVDPLSISFVLLITGVGS
                     LIHIYSIGYMAEDPDRRRFFAYLNLFVAAMLLLVLGNNFLVLFLGWEGVGLASYLLIGF
                     WQYKPTAATAAKKAFVVNRVGDIGLILAIALMFSTFGTVGFDQILGTGAEHVGLASQLS
                     TGTATAIGLLLLLGACGKSAQLPLQSWLLDAMEGPTPVSALIHAATMVTAGVYLIVRSG
                     PIFEMSDTAQLVVTIVGAATLLAGAIIGCGKDDIKKALAGSTMSQIGYMHLAAGLGKPG
                     YVFAIAHLIAHGFFKAGLFLGAGSVMHGMKDDVNMRHYGALRTMMVITYATFGLGYLAI
                     IGFPGLSGWFTKDGIIEAAFDKGGTSGAILGTCALVGAGITAYYMSRVMFMTFFGEKRW
                     AEDVHPHESPKVMTVPLMLLAVGSVFAGGFLILGGFSDFLEPVVGAPEHEHEFKLITAA
                     GAGTFVLMVIGVAIAWRQYGSRKVPREAPAGSFVTVAARKDLYGDALNESLLMRPGQWL
                     TRLAVWFDGRGVDGAVNGLAAGVGGSSGRIRRLQTGFARSYALSMFFGAALVVAALLVV
                     NVS"
     gene            6731..8311
                     /locus_tag="K2F47_RS11580"
     CDS             6731..8311
                     /EC_number="1.6.5.9"
                     /GO_function="GO:0008137 - NADH dehydrogenase (ubiquinone)
                     activity [Evidence IEA]"
                     /GO_process="GO:0042773 - ATP synthesis coupled electron
                     transport [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019632350.1"
                     /locus_tag="K2F47_RS11580"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="NADH-quinone oxidoreductase subunit M"
                     /protein_id="WP_242902878.1"
                     /transl_table=11
                     /translation="MNDFPWLSVLIALPLVGAVLVAVLPREREALVKQVALGASAVTLA
                     VALVMAARFDAGGSRFQFTEKYWWIKEFGVHWAVGVDGVALVLIVLSVILVPLVILASW
                     TEDDRSGGVDVPAKRSVKTYMALLLTLEAAMIGVFAATDVFLFYVFFEAMLIPVYFIIG
                     YFGGPQRSYAAVKFLLYSLFGGLLMLVAVIWLYPLSAKSTADGGLGHGTFMFDELSKMN
                     IDPTTAKWLFLGFFVAFAIKAPMVPVHTWLPDAAQQSPPGALVLIVGVLDKVGTYGMLR
                     FCLELFPGAAKWATPVVLGFAVLSIIYGAVLAIGQVDLKRLIAYTSVSHFGFIVLGIFA
                     MTSQGQSGATLYMVNHGFSTGALFLIVGFMIVRRRSARIGDYGGVQKVAPVLAGTFLVA
                     GLSGLSLPGLSTFVSEFLVIVGTFSRYRWAAVLAVSGVVLAAIYILWMYQRTMGGPKAP
                     AVEGMRDLTAREKWAIAPILAIIVAMGLFPQPVLHVINPSVKETLVRVDRHDPAPKTTG
                     NVAENGARP"
     gene            8308..9897
                     /gene="nuoN"
                     /locus_tag="K2F47_RS11585"
     CDS             8308..9897
                     /EC_number="7.1.1.2"
                     /GO_function="GO:0008137 - NADH dehydrogenase (ubiquinone)
                     activity [Evidence IEA]"
                     /GO_process="GO:0042773 - ATP synthesis coupled electron
                     transport [Evidence IEA]"
                     /codon_start=1
                     /gene="nuoN"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018654737.1"
                     /locus_tag="K2F47_RS11585"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="NADH-quinone oxidoreductase subunit NuoN"
                     /protein_id="WP_242902879.1"
                     /transl_table=11
                     /translation="MSRSSQVSAVLAQGGDIPAPHIEYDQIGPLLLVLGIAVAGVLVEA
                     FVGRTWRYYAQVPLAFLGLAGAFAWTIVLGVHDEPHHVAAEGALGVDGPTLFLQGTILV
                     LALVSLLLIAERGGSVVGGGHFAAQASALPGSEAEQRSAAAGITQTEVFPLMMFAVGGM
                     LMFPASNDLLTMFVALEVMSLPLYLLCGLARRRRLLSQEAAVKYFLLGAFSSAFFLYGT
                     ALLYGYAGSVRLADISAEISKDAGSETLLLAGVALLSVGLLFKLGAVPFHMWKPDVYQG
                     APTPITALMASCTLVAAFGAILRVYYVAFETLKWDWEPIMWGVAILTMVIGAVIAITQT
                     DLKRMLAYSSVAHAGFLLTGVVATSKDGLSGSLFYLAAYGFTTIGAFAVITMVRDAGGE
                     AAHLSRWAGLGKRSPVVAGTFAFFLLAFAGIPLTSGFTGKFAVFKAAVQADATPLVIVG
                     VISSAIAAFFYVRVIVVMFFSEPEADGPTVVAGPATAAAVALGLTATVVLGVLPQPILD
                     LAGHATTHMFVR"
     gene            10001..10975
                     /locus_tag="K2F47_RS11590"
     CDS             10001..10975
                     /EC_number="2.5.1.-"
                     /GO_function="GO:0004659 - prenyltransferase activity
                     [Evidence IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /GO_process="GO:0008299 - isoprenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: PT_FPPS_like"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PT_HPP"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1182: Polyprenyl synthetase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018654738.1"
                     /locus_tag="K2F47_RS11590"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="polyprenyl synthetase family protein"
                     /protein_id="WP_242905906.1"
                     /sec_met_domain="PT_FPPS_like (E-value: 8.6e-58, bitscore:
                     192.5, seeds: 145, tool: rule-based-clusters)"
                     /sec_met_domain="PT_HPP (E-value: 8.5e-44, bitscore: 146.9,
                     seeds: 4, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MHVDAALAADAKRRLAAVEALLLESVQGEDALLTEASKHLVVAGG
                     KRFRPMLVLLASHFGDPAAAGVVPAAVVVELTHLGTLYHDDVMDEATVRRGRESANSRW
                     TNTVAILTGDYLFARASDLLADLGPEAVRIQARAFARLVRGQIQETVGPAEGADPLKHY
                     LQVVADKTASLIAVSGQFGALLSGAPASVVDTVTSACEKIGIAFQLSDDILDIDSDAEQ
                     SGKTPGTDLREGIRTLPVHHVLAGTDEKDARLRELLVQDLSDDDALHAEALALLRAHPA
                     MDLARADLRRWAEDARAELLTLPDIPARSAFTGLCDYVVSRTG"
     gene            complement(10986..11591)
                     /locus_tag="K2F47_RS11595"
     CDS             complement(10986..11591)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018654751.1"
                     /locus_tag="K2F47_RS11595"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="ATP/GTP-binding protein"
                     /protein_id="WP_242902880.1"
                     /transl_table=11
                     /translation="MDSGPSRREVRARRLPTAVKIVIAGGFGVGKTTMVGTVSETQPLR
                     TEELLTDESVGIDDMAGVERKKTTTVAMDFGRITMRDDYVLYLFGTPGQERFWFMWDEV
                     ALGALGAVVLADTRRLSDCFPSVDYFERRSTPFVVAVNCFEGARAYELEEIQLALNLGP
                     KVPVMLCDARELGSCKQVLIDLVLHAMKSRGLTETQSV"
     gene            complement(11572..12018)
                     /locus_tag="K2F47_RS11600"
     CDS             complement(11572..12018)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018654752.1"
                     /locus_tag="K2F47_RS11600"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="DUF742 domain-containing protein"
                     /protein_id="WP_242902881.1"
                     /transl_table=11
                     /translation="MMPPEEHPLDPWRDEPPPAVPAPRPPVQDPRLLAEGTGPMVRPYV
                     MTSGRIEPTRGRFDLITLVVAEGPEPEGAIGLGPEHLAIIRLCQSVLSVAEITGRLDLP
                     VATVRVLLGDLFDKGFVSLQEPEPEADMHDIRLYKAVIDGLRAL"
     gene            complement(12015..12437)
                     /locus_tag="K2F47_RS11605"
     CDS             complement(12015..12437)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018654753.1"
                     /locus_tag="K2F47_RS11605"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="roadblock/LC7 domain-containing protein"
                     /protein_id="WP_242905908.1"
                     /transl_table=11
                     /translation="MQKTGPSSDLGWLLDDLVHRLPHTRSAVVLSADGLLMASSKGMTQ
                     DDGEHLAAVSAGIQSLAKGAGTRFGGGPVRQTIIEMQSAFMLVTVAGKGACLAVLAGEE
                     ADVGLVAYEMAMLVTAMGQHLSSPARTEAAAEGRTS"
     gene            complement(12437..12730)
                     /locus_tag="K2F47_RS11610"
     CDS             complement(12437..12730)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="K2F47_RS11610"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_242902882.1"
                     /transl_table=11
                     /translation="MADISTTPSGLPVRVPQANLAEPLRTGEADAAGRPDEEDDPGRSP
                     EEIKQIMGSYQRGTRRGRTDAAGAANGAPAGAASAAASGALGSHAEEGEEGQ"
     misc_feature    13118..13131
                     /note="TFBS match to PerR, Peroxide regulator, confidence:
                     weak, score: 14.02"
                     /tool="antismash"
     misc_feature    13183..13197
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence: weak,
                     score: 16.69"
                     /tool="antismash"
     gene            complement(13220..14881)
                     /locus_tag="K2F47_RS11615"
     CDS             complement(13220..14881)
                     /GO_function="GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: T2TS"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018654755.1"
                     /locus_tag="K2F47_RS11615"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="prenyltransferase/squalene oxidase
                     repeat-containing protein"
                     /protein_id="WP_242902883.1"
                     /sec_met_domain="T2TS (E-value: 6.8e-81, bitscore: 269.2,
                     seeds: 58, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MGTAGEETGEISAGNGRGGGCALAEADRAPATGAAARTRAGAQAL
                     VAGLTSEPWGQVSPSVYETGRLVSLAPWLTGHEERLRFLLAAQRQDGGWGARDGYAIVP
                     TLSATEGVLSSLRARDSGLDPQVLARAADRGLRAADALLTGGRGRPVPDMPAIELISAY
                     LTELLNGHLAALDAAPISGLDAWLGGARLSLPHGWDGALLEPIRARIAAGRSVPTKMVH
                     ALEIAGPAARGSASVSPGPRTGAVGASPAATAAWLGGSVPPPGDRARRFLERAARLHGG
                     PVPCGLPITVFEQAWTLSGTVRAGVPIQVPEGQRKELAAALGPEGTPAGEGLPADADTT
                     AVTLYTLALLGAPHEPDSLLAFELDEHFCTWQGEQGASVTTNAHVLDAFGQYVKSRPAA
                     APRYARAIAKAASWLLGQQRPDGSWSDRWHVSPYYATACATAALRSFGGEAAREPVRRA
                     LRWVVDTQRVDGSWGLWDGTAEETAQAVQALLLGRGAMAGMSRSIPSVGAAVRGRAWLE
                     RFSGRTSDPPLWHDKDLYLPRAIVRGTVLAALHLAR"
     misc_feature    15382..15397
                     /note="TFBS match to LexA_variant_1, Repressor of DNA
                     damage response, confidence: weak, score: 22.52"
                     /tool="antismash"
     misc_feature    complement(15436..15451)
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: weak, score: 16.22"
                     /tool="antismash"
     gene            complement(15445..15825)
                     /locus_tag="K2F47_RS11620"
     CDS             complement(15445..15825)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="K2F47_RS11620"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_242902884.1"
                     /transl_table=11
                     /translation="MRLLSVTMLGSGLVIAGLAAPAAGQASGMGRGEISVEPGVARPGQ
                     RVEVSVPRCAQPREAVSPAFTRQIALRGKADHGEGVASVRRDAKPGHYTITARCGARTV
                     TGRFKVSNGLAWPAILPTSDGL"
     gene            complement(15877..16782)
                     /gene="rarD"
                     /locus_tag="K2F47_RS11625"
     CDS             complement(15877..16782)
                     /GO_component="GO:0005886 - plasma membrane [Evidence IEA]"
                     /GO_function="GO:0005215 - transporter activity [Evidence
                     IEA]"
                     /GO_process="GO:0006810 - transport [Evidence IEA]"
                     /codon_start=1
                     /gene="rarD"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012854713.1"
                     /locus_tag="K2F47_RS11625"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="EamA family transporter RarD"
                     /protein_id="WP_242902885.1"
                     /transl_table=11
                     /translation="MRGVKRGVLCGVGAYALWGLFPLYWPLLKPAGAAEILAHRIMWSL
                     VTVAVVLAVKRNWGWIRTLGRRRIGLLTLAAVTISVNWGVFIYAVNSGRTIEGALGYFI
                     NPLISVVFGVVVFRERLRAWQWGAVGLGAAAVVLLTADYGEPPWIALILAFSFGTYGLL
                     KKFAAMPSAESLGVETAAMFVPALVVSLVLEGRGDAAFGHAGTGHAVLLATAGLVTAVP
                     LMLFNAAAIRLPLSMIGMLQYLAPALQFLIGLLVQGEEMPASRWTGFLLVWLALIVLTW
                     DGLNAARRAPQIPEPVSEAA"
     misc_feature    complement(16845..16858)
                     /note="TFBS match to LexA_variant_2, Repressor of DNA
                     damage response, confidence: medium, score: 20.7"
                     /tool="antismash"
     gene            16852..17505
                     /gene="msrA"
                     /locus_tag="K2F47_RS11630"
     CDS             16852..17505
                     /EC_number="1.8.4.11"
                     /GO_function="GO:0008113 - peptide-methionine (S)-S-oxide
                     reductase activity [Evidence IEA]"
                     /GO_function="GO:0033744 -
                     L-methionine:thioredoxin-disulfide S-oxidoreductase
                     activity [Evidence IEA]"
                     /GO_process="GO:0006979 - response to oxidative stress
                     [Evidence IEA]"
                     /GO_process="GO:0030091 - protein repair [Evidence IEA]"
                     /codon_start=1
                     /gene="msrA"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017538078.1"
                     /locus_tag="K2F47_RS11630"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="peptide-methionine (S)-S-oxide reductase MsrA"
                     /protein_id="WP_242902886.1"
                     /transl_table=11
                     /translation="MFAKTQLVTPENALPGRDTPLPVPPRHEVLDAPLAPPFPAGTEIA
                     EFALGCFWGAERRFWQTPGVVSTSAGYEGGHTPNPTYEEVCSGLTGHTETVRVVYDPSK
                     VSYDDLLRVFWESHNPTQGMRQGNDVGTQYRSAIFYRTDAQRAAAEASRDAYQPVLTAA
                     GHGPITTELTPATTFYYAEDYHQQYLSDTKNPNGYCGLGGTGLSCPVGAAGTTS"
     gene            17615..18043
                     /locus_tag="K2F47_RS41320"
     CDS             17615..18043
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF017757.5"
                     /locus_tag="K2F47_RS41320"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="WP_308198401.1"
                     /transl_table=11
                     /translation="MLLGEPYTRQLHGKLRELRFYLGTEAVRVTYWIAPGKRFILLTVF
                     HETRMREVERARRALRLCVAEAHMVDAGEGRGRWVAGPTGVSCGNAAWASPAPSRPTPL
                     LAWPTSWDVPSAPCVRSVGGARGSCRGSGDDAVRRGQV"
     gene            18015..18140
                     /locus_tag="K2F47_RS41325"
     CDS             18015..18140
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF024949.5"
                     /locus_tag="K2F47_RS41325"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="WP_308198402.1"
                     /transl_table=11
                     /translation="MTQSAVARFETGGTIPTLLVLERLAKALGAELVVQLRTPAA"
     gene            complement(18171..18614)
                     /locus_tag="K2F47_RS11645"
     CDS             complement(18171..18614)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012888502.1"
                     /locus_tag="K2F47_RS11645"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="hypothetical protein"
                     /protein_id="WP_242902887.1"
                     /transl_table=11
                     /translation="MARRVTGSPLVGPAFVLDAQGLSLLADDDRRMTARLELAVRQEFM
                     PVISAVTVAEQRRADRAGKRLAWLRSRLTIVPVTEDIADAAAALLDSTGLSGHECVIDA
                     LVVATAASATGPAKVVSSDGSHIPTLCKTASADRPSPVDWLKV"
     gene            complement(18599..18892)
                     /locus_tag="K2F47_RS11650"
     CDS             complement(18599..18892)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012888501.1"
                     /locus_tag="K2F47_RS11650"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="hypothetical protein"
                     /protein_id="WP_242902888.1"
                     /transl_table=11
                     /translation="MADTRDPEQRSPGRRVRRATGGRYGKTVKKSVTLRESVVEQIEAR
                     TGARGFSEFLDAAAERHLSLLKAQEIVDDHVARHGEFTPEELAEAEFAWRGE"
     gene            complement(18958..20625)
                     /locus_tag="K2F47_RS11655"
     CDS             complement(18958..20625)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) DAO"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF013739.5"
                     /locus_tag="K2F47_RS11655"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="WP_242902889.1"
                     /sec_met_domain="DAO (E-value: 1.8e-07, bitscore: 27.9,
                     seeds: 521, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MENSAKGSSRRNFLGMAASAGLLQVMTGALPAHAEPAPTGLFTPP
                     TRKASGRSVAVLGAGVSGMTVAVKLHQAGYAVTVLEAQDRTNGRARTLRRGDTITEVWA
                     DGSSHTLTCQFDQGLYLNIGPSRLSHQHQRVFALCRRFHIPLEPYIMQSTANLYQTDKA
                     FQKASRTYRQIAFDTRGYVAEYAAAAVKKGLLDSDKLTDSQREKLLILLTEFGQLDKTD
                     HAFNGSTRSGLAKPLGVPQAAEGVAPLPLIALLESEFWNDQFFRGDDIVWQNSMFQAVG
                     GMDAIVRSIAKTVPAGIITLNAPVHAIKLTDDNVRVSWRDADGTHDKTFDHCLSSIPIP
                     VLRQRVHLEGFSPEFNWAVENAQNSGAVKVGWQVSQRFWESDRYQIYGGISWLGNLARQ
                     IVYPSNDCFAPGKATLTGAYSSYDAGRQLGEQTHLQRLATAREAGAKLHQEFLSRAIVP
                     DEKAISIAWQKVPYIQHGWAHWDPEIPDHKRIYQTLIYPQGNNRFLVIGDQVSPLPGWQ
                     EGALMSAEWAFQWTNGDRRQSETRTPVHQIPDSKSLTT"
     gene            complement(20928..21431)
                     /locus_tag="K2F47_RS11660"
     CDS             complement(20928..21431)
                     /EC_number="2.3.-.-"
                     /GO_function="GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA]"
                     /GO_function="GO:0016746 - acyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1111: GCN5-related N-acetyltransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF024698.5"
                     /locus_tag="K2F47_RS11660"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="WP_242902890.1"
                     /transl_table=11
                     /translation="MSVVETERLLLRPLTGDDFDDYAAMLADPDVTGGLAESVGTSPAD
                     AWRSLATFIGHREIRGYSHWAIVEKSTGRFAGRAGPWRPHGFPGLGVGWCLARDHWGKG
                     YAAEAGRAAVAYCFTELGADEVISVILPSNVRSIAVATRIGHTHLRDTTYRSQRVHIYG
                     QSRP"
     gene            complement(21548..21832)
                     /locus_tag="K2F47_RS11665"
     CDS             complement(21548..21832)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="K2F47_RS11665"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_242902891.1"
                     /transl_table=11
                     /translation="MNRLLTVIGHAPLTTLRKRNSVERAELEQKLGEPHVQLARRTSAG
                     DIGSINGLTPGPTGEMITMARQQLIKSPKPPRQPSPPDLRTPSGRLLPY"
     misc_feature    complement(21674..21676)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            complement(21835..22722)
                     /locus_tag="K2F47_RS11670"
     CDS             complement(21835..22722)
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012893289.1"
                     /locus_tag="K2F47_RS11670"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="ABC transporter permease"
                     /protein_id="WP_242902892.1"
                     /transl_table=11
                     /translation="MTTGEITATEGGSGAAAAGGSGYRVRRTLPLRVEAIRQFRRRRTL
                     VAFGILLVLPWVLVGAFKIGGDPGPDGVPSLVDVATASALNFALFALFVSTGFLLVVAV
                     ALFCGDTVASEAGWSSLRYLLAAPVPRARLLRQKLAVALSYAVVAVVSLPLMALVAGTV
                     GFGWGPVELPTGGTVPAGTALGRMAIIIGYSLVAQLVVAALAFLLSVTTDSPLGAVGGA
                     VGLVIVSNILDAVTALGSWRDFLPTHWMYSWMDALQPQIQWTGMAKGSAISLSYTAVLF
                     ALAFRRFRNRDIVS"
ORIGIN
        1 gaggcgctgg agatcgccgc gcgcggtctc gcggcggcgc gcggctcggc gggcgtgctg
       61 accggcgggc gggtcacgct ggaggacgcc tacgcctacg ccaagttcgc gcggatcgcg
      121 ctcggcacca acgacgtcga cttccgcgcc cgtccgatgt cggacgagga gtcgcggttc
      181 ctcggctcgt cggtggcggg ccgtccgatc gaggtgacct acgccgacct ggagaaggcg
      241 cccgcggtgc tgctcgccgg cttcgagccg gaggaggagt cgccgatcgt gttcctgcgg
      301 ctgcgcaagg cgtaccgcaa gaaggcgctg aaggtcttcg cggcggcgcc gttcgcgacg
      361 cgcggcctgc gcaaggtcgg cgggacgctg ctgccgacgc agccgggcgc cgaggccgag
      421 acgctcggct cgctgatcgg cgagggcggg ccctccggcg tgcgcgcgct gctggagacg
      481 cccggcgccg tgatcatggt cggcgagcgg ctcgcgggca gcccgggcgc gctgtcggcc
      541 gtcgtgcggc tcgcgcaggt gaccggggcc cggctggcgt gggtaccgcg ccgggccggg
      601 gagcgcggcg cggtcgaggc cggggcgctg cccgggctgc tgccgatcgg ccgcccggtc
      661 gccgacgccg gggcgcgcgc ggaggtcgcc cgtgcctggg gcgtcgccga actgcccgcc
      721 gagccggggc tcggcaccga ggcgctcatc gaggcggcgg cgcaggggcg gcgcggcgcg
      781 ctgctcgtcg gcggcgtcga ccccgaggac ctgcccgacc cgcaggccgt gctcgcggcg
      841 ctggaggcga cgccgttcgt ggtgagcctg gagcagcgtc cgagcgccgt caccgaccgc
      901 gccgacgtgg tgctgccggt cgcggccgtc gccgagaagt ccggcacgtt cgtcgactgg
      961 gagggccgcg gccgccagtt cgaggtcgtg ctgaggtccg ccgggcggct ctccgacctg
     1021 cgggtgctga actcgctggc cgacgagatg gacgtccacc tcggcctgcc cgggccggac
     1081 gcggcgcgcc gcgagctgac cgggctcggc gcctaccgcg gcgagcgccc ggacgcgccg
     1141 cacgtgccgc aggtgatcac gccgcacccc gagcggggcg aggcgctgct ggcgacctgg
     1201 cggctgctgc tcgaccgggg ccgcctccag gacggcgagc cgtacctcgc gggcaccgcc
     1261 aagcccgcgg cggcgcggct gtcgcccgcg acggccgccg agatcggcgc ggacggcccg
     1321 gacggcgcgg tgcgcgtgtc gggcccgcgc ggcgaggtca cgctcccgct ggagatcacc
     1381 accgacctgc cggaccgcgt cgtgtggctg ccgacgaact cggcgggctg cgccctgtac
     1441 cgcgacatcg gcgcggtggc gggcgacgtg gtgcgcgtcg cgggcgcccc gggcggtacg
     1501 ctctccggcg ccgccccgcg tggcggcgcc atcgcggcca gggacgtccc gggcggcgtg
     1561 gccgacgcac ccgccgacgc acccgccgac gaccccgctg gaggctcccg atgagtccgc
     1621 tcacgctcgc ggcggcgtcc gcgaaggaac ccacgctgaa gagcttcggc gacgacccgt
     1681 ggtggctgat cggcggcaag gtcctcgcga tcttcgtctt cctggtgctg accgtcctgc
     1741 tgtcgatgtg ggtcgagcgc cgcgtgatcg cccggatgca gctccgggtc ggcccgaacc
     1801 gggtcggccc gcagggcctg ctccagggcc tcgccgacgg cgtgaagctg gcgctcaagg
     1861 aggacatcgt cccgcgccag gtcgacaagc tggtgttcgt cctggcgccg atcgtgtcgg
     1921 ccgtcccggc gttcatctcc ttcatcatca tcccgttcgg gccgacggtg tcggtgttcg
     1981 ggcaccagac cgcgctccag ggcaccgacc tcccggtcgc ggtgctgctc gtgctcgcga
     2041 tgtcctcgat gggcgtgtac gggatcgtgc tggccggctg gtcgtcgatg tcgccgtact
     2101 cgctgctcgg cgggctccgc tcgtccgccc aggtgatctc ctacgagatc gcgatgggcc
     2161 tgtcgttcgt cgcggtgttc ctgttcgcgg ggtcgatgtc gacctccgac atcgtcgccg
     2221 cgcagcacga caagtggttc gtggtgctgc tgctgccgtc cttcctcgtg tacgtgatca
     2281 cgatgatggg cgagtcgaac cgcatcccgt tcgacctgcc cgagggcgag ggcgagctgg
     2341 tcggcggctt ccacaccgag tactcgtcgc tgaagttcgc gatgttcttc ctcgcggagt
     2401 acatcaacct cgcgacgctg tcggcgctcg ccacgacgct gttcctcggc ggctggcggg
     2461 ctcccgcgcc gatctccacg gtgtgggcgg gcgccaacgc cggctggtgg ccggtgctgt
     2521 ggttcctggt caagctgtgg ctgttcatct tcttcttcat ctggctccgc ggctcgctgc
     2581 cgcgcgtccg ctacgaccag ctgatgaagc tgggctggaa ggtgctcatg cccttctcgc
     2641 tcggctggat cctgctggtg tcgacgatcc gcgcgctgcg caacgagggc cacgacatgc
     2701 ggcagatcgt catcatcgcc gccgtggtcg cggcggtggt gctggtggcc acggtgatct
     2761 gggagatgct ccgcggcggc gaggacgaga aggagatcgt ccccggcgcg ggtcgggacg
     2821 ccgcgcccga tccggcggcc ggcgggttcc cggtgccgcc gctggacctg ccgcactacc
     2881 acggcggtcc ggccggggcc accaaggtca aaacccctcc tgaggaggtc accagtggga
     2941 ctcactgatt tcctgaatcc cgtcaagggg ttcggggtct cgttccacca gatgttcagc
     3001 aagagcgaga ccgttcagta ccccgaggtg aagaagccga ccgcgccgcg cttccacggc
     3061 cggcaccagc tcaaccggtg gccggacggg ctggagaagt gcgtcgggtg cgagctgtgc
     3121 gcctgggcgt gccccgccga cgccatcttc gtcgagggcg ccgacaacac cgtcgacgag
     3181 cgctactcgc ccggcgagcg gtacggccgc atctaccaga tcaactatct gcgctgcatc
     3241 ctgtgcgggc tgtgcatcga ggcgtgcccc acccgggcgc tcacgatgac caacgagtac
     3301 gagctcgccg acgacagccg cgagagcctg atctacacca aggagatgct gctggcgccg
     3361 ctgcgcgagg gcatggagca gccgccgcac gagatgcggc tcggcgacac cgaggaggag
     3421 tactaccgcc tcggcctcca gcccgaggag tccgccgcgg ctcccgcgga gagcggcggc
     3481 gcgtccgcgg cgaagcgccc gcgcggacgc aagggcggtg acgccaagtg agcgccgcgc
     3541 tgaccggcca cgcgctggcg gggcacgtcg cctccgggca cgtcctggcc gggcacgtcg
     3601 ccgacaagca gtccggcgag ccgttcttct tctggctgct ggccgtcgtg tcggtctgcg
     3661 ccgccctcgg catgatcttc atgcggaagg cggtgcactc ggcgctgctg ctggcgaccg
     3721 tgatgctctc gctggccgcg ctgtacgcga tccaggacgc gccgttcctc gcgttcgtcc
     3781 aggtcatcgt ctacaccggc gcggtgctca tgctgttcct gttcgtgctg atgctggtcg
     3841 gggtcagctc caccgactcg ctggtggaga cgatcagggg ccagcggttc tgggcggcgg
     3901 tcggcgcgat cgggttcgtc gtgctactgg cgatcgggct cgggaacgcg gcgctcggcg
     3961 actcggccgg gctgaagacc gcgaacggcg acggcaacgt cgtcggcctc gcgcggctgc
     4021 tgttcaagga ctacgtgttc gcgttcgagg cgaccagcgc cctgctgatc acggcggcgc
     4081 tcggcgcgat ggtgctcgcg caccgcgagc ggaccgagcc gaagccgacg cagcgcgacc
     4141 tgtccaaggg ccggttcctg tccggcgagc accccggccc gctgccgggc ccgggcacct
     4201 acgcccggca caacgccgtc gacatgccgg cgctgctgcc cgacgggacg ccgtccgagc
     4261 tgtcggtcaa cccgatcatc gcggcccgga ccgacaccgt cgagcggcac gtcgacctgc
     4321 acggcgagac cgaggaggag gccctcgggc acgacgtcgc ggcggtgcgc gccgtgaccg
     4381 gtgaggcgcg ggacgcgggc gccgagtcgc gcgtcgtcaa ggccgggtcg ccggtcgcgg
     4441 gcgggccctc cgagggcggc gccggcggcg ggacgtccgg caacgagcgt gaaggcgagg
     4501 ctggtcaatg agtccggggc actatctggc gctctcggcg atcctgttca ccatcggtgc
     4561 gctcggcgtc ctcgtgcgcc gcaacgcgat cgtggtgttc atgtgcgtcg agctcatgct
     4621 gaacgcgacg aacctggcgt tcgtctcgtt ctcccgcatg cacggcgagc tggacggcca
     4681 gatcatcgcg ttcttcgtga tggtggtggc cgcggcggag gtcgtggtcg gcctggcgat
     4741 catcatgacc atcttccgaa cgcgcaggtc ctcgtcggtc gacgacgcca acctgctgaa
     4801 gtactgagag gccggggatg aaagcggaag gcatccaggc cgcgtcctgg cttctcatcg
     4861 cgctcccgct cgcgggcgcc gcgatcctcc tgctcggggg gaggcgcacc gaccggtggg
     4921 gccatctgct cggcgtcacg atgtcgctgg cctcgttcgt cgtgggcgcg gcgatgttcg
     4981 tccagatgct cgggtacgag gccgaggagc ggcgccggac cctgcacctg tgggacttca
     5041 tcgacgtcgg ctcgttcaag gtcggcatgg acctgctggt ggacccgctg tccatcagct
     5101 tcgtcctgct gatcaccggt gtgggctcgc tcatccacat ctactccatc ggctacatgg
     5161 ccgaggaccc cgaccggcgc cggttcttcg cctacctgaa cctgttcgtc gcggcgatgc
     5221 tgctgctggt gctcggcaac aacttcctgg tgctgttcct cggctgggag ggcgtgggcc
     5281 tcgcgtccta cctgctgatc gggttctggc agtacaagcc gaccgcagcg accgccgcga
     5341 agaaggcgtt cgtcgtcaac cgcgtcggcg acatcggcct gatcctcgcg atcgcgctga
     5401 tgttctccac gttcgggacg gtcggcttcg accagatcct cggcaccggc gccgagcacg
     5461 tgggcctcgc gtcccagctc agcaccggca ccgccaccgc gatcgggctg ctgctcctgc
     5521 tcggcgcgtg cggcaagtcc gcgcagctgc cgctccagtc ctggctgctg gacgcgatgg
     5581 agggcccgac cccggtgtcg gcgctcatcc acgccgcgac gatggtgacc gccggcgtct
     5641 acctgatcgt ccggtccggg ccgatcttcg agatgtccga caccgcgcag ctggtggtga
     5701 cgatcgtcgg cgcggccacg ctgctcgccg gtgcgatcat cgggtgcggc aaggacgaca
     5761 tcaagaaggc cctcgccggg tcgacgatgt cgcagatcgg ctacatgcac ctcgccgcgg
     5821 ggctcggcaa gcccggttac gtcttcgcca tcgcgcacct catcgcgcac ggcttcttca
     5881 aggcgggcct gttcctcggc gccgggtcgg tcatgcacgg catgaaggac gacgtgaaca
     5941 tgcgccacta cggcgcgctc cgcacgatga tggtgatcac ctacgccacg ttcgggctcg
     6001 gctacctcgc gatcatcggg ttcccgggcc tgtcgggctg gttcaccaag gacggcatca
     6061 tcgaggccgc gttcgacaag ggcggcacgt ccggggcgat cctcggtacg tgcgcgctgg
     6121 tcggcgcggg catcaccgcc tactacatgt cgcgcgtgat gttcatgacg ttcttcggtg
     6181 agaagcgctg ggccgaggac gtccacccgc acgagtcgcc gaaggtgatg accgttccgc
     6241 tgatgctgct ggcggtcggc tcggtgttcg cgggcggctt cctcatcctc ggcgggttct
     6301 ccgacttcct ggaaccggtc gtcggggcgc ccgagcacga gcacgagttc aagctgatca
     6361 ccgccgccgg cgccggcacg ttcgtgctga tggtcatcgg cgtcgcgatc gcctggcggc
     6421 agtacggcag ccggaaggtg ccgcgcgagg cgcccgccgg ctcgttcgtc accgtcgccg
     6481 cccgcaagga cctgtacggg gacgcgctga acgagtcgct gctgatgcgg cccgggcagt
     6541 ggctgacccg gctcgcggtc tggttcgacg gacgcggcgt cgacggcgcc gtcaacggcc
     6601 tggccgcggg cgtcggcggc agctccgggc gcatccggcg gctccagacc ggcttcgccc
     6661 gctcctacgc cctttcgatg ttcttcggcg cggctctcgt cgtcgcggcg ctcctggtgg
     6721 tgaacgtgtc gtgaatgact ttccctggct gagcgtcctg atcgcgctgc cgctcgtcgg
     6781 cgcggtgctc gtggcggtgc tgccgcgcga gcgcgaggcg ctggtcaagc aggtcgcgct
     6841 cggcgcgtcc gcggtcacgc tggcggtcgc gctggtgatg gcggcccgct tcgacgcggg
     6901 cggctcgcgg ttccagttca ccgagaagta ctggtggatc aaggagttcg gcgtccactg
     6961 ggcggtcggc gtcgacggcg tcgcgctcgt gctgatcgtg ctgtcggtga tcctcgtccc
     7021 gctggtgatc ctcgcgtcct ggaccgagga cgaccggtcg ggcggcgtgg acgtccccgc
     7081 caagcggtcg gtgaagacct acatggcgct gctgctcacg ctggaagcgg cgatgatcgg
     7141 cgtgttcgcc gcgaccgacg tgttcctgtt ctacgtcttc ttcgaggcga tgctgatccc
     7201 ggtgtacttc atcatcgggt acttcggcgg cccgcagcgc tcctacgcgg cggtgaagtt
     7261 cctgctgtac tcgctgttcg gcgggctgct gatgctcgtc gcggtgatct ggctgtaccc
     7321 gctgtcggcc aagtccaccg ccgacggcgg cctcgggcac ggcacgttca tgttcgacga
     7381 gctgtcgaag atgaacatcg acccgaccac ggccaagtgg ctgttcctcg gcttcttcgt
     7441 cgcgttcgcg atcaaggcgc cgatggtgcc ggtgcacacc tggctcccgg acgcggcgca
     7501 gcagtccccg cccggcgcgc tcgtgctgat cgtcggcgtc ctggacaagg tcggcaccta
     7561 cgggatgctg cggttctgcc tggagctgtt ccccggcgcc gccaagtggg ccacgccggt
     7621 cgtgctcggg ttcgcggtgc tcagcatcat ctacggcgcc gtgctcgcga tcggccaggt
     7681 cgacctcaag cggctcatcg cctacacctc ggtctcgcac ttcgggttca tcgtcctcgg
     7741 catcttcgcg atgacgtcgc aggggcagtc cggcgcgacc ctctacatgg tcaaccacgg
     7801 gttctccacc ggcgcgctgt tcctgatcgt cggcttcatg atcgtccggc ggcggtcggc
     7861 gcggatcggc gactacggcg gggtgcagaa ggtcgcgccc gtcctcgccg ggacgttcct
     7921 cgtcgcgggc ctgtccgggc tgtcgctgcc cggcctgtcc acgttcgtat cggagttcct
     7981 cgtcatcgtc gggacgttca gccgctacag gtgggccgcc gtgctcgcgg tcagcggcgt
     8041 cgtgctcgcc gcgatctaca tcctgtggat gtaccagcgg accatgggcg ggcccaaggc
     8101 cccggccgtc gagggcatgc gggacctgac cgcgcgcgag aagtgggcga tcgcgcccat
     8161 cctcgcgatc atcgtggcga tgggcctgtt cccgcagccg gtgctgcacg tcatcaaccc
     8221 ttcggtgaag gagacgctgg tccgggtcga tcggcatgat cccgcgccga agaccaccgg
     8281 gaacgtcgcc gagaacggag cccgtccatg agccgcagca gtcaggtgag cgccgtcctc
     8341 gcgcaggggg gtgacatccc ggcgccgcac atcgagtacg accagatcgg cccgctgctg
     8401 ctcgtgctcg ggatcgccgt cgccggcgtg ctggtcgagg cgttcgtcgg acgcacctgg
     8461 cgctactacg cgcaggtccc cctcgccttc ctcggcctcg ccggcgcgtt cgcgtggacg
     8521 atcgtcctcg gcgtccacga cgagccgcac cacgtcgccg ccgagggcgc gctcggcgtg
     8581 gacggcccca ccctgttcct ccagggcacc atcctcgtgc tcgcgctcgt cagcctcctg
     8641 ctgatcgccg agcgcggcgg cagcgtcgtc ggcggcgggc acttcgccgc gcaggcgtcc
     8701 gcgctgccgg gcagcgaggc cgagcagcgc agcgccgccg ccgggatcac ccagaccgag
     8761 gtgttcccgc tgatgatgtt cgcggtcggc gggatgctga tgttcccggc gtccaacgac
     8821 ctgctcacga tgttcgtggc gctggaggtc atgtcgctgc cgctgtacct gctgtgcggg
     8881 ctcgcccgcc ggcggcgcct gctctcgcag gaggcggcgg tcaagtactt cctgctcggc
     8941 gcgttctcct cggcgttctt cctgtacggg acggcgctgc tgtacggcta cgcgggctcg
     9001 gtgcggctcg ccgacatctc cgccgagatc agcaaggacg ccgggagcga gacgctgctg
     9061 ctcgcgggcg tcgcgctgct gtcggtcggg ctgctgttca agctcggcgc ggtgccgttc
     9121 cacatgtgga agccggacgt ctaccagggc gcccccaccc cgatcacggc gctgatggcg
     9181 tcctgcacgc tcgtcgccgc gttcggcgcg atcctgcgcg tctactacgt cgcgttcgag
     9241 acgctcaagt gggactggga gccgatcatg tggggggtgg ccatcctcac gatggtcatc
     9301 ggcgccgtca tcgcgatcac ccagaccgac ctcaagcgga tgctggccta ctcctcggtc
     9361 gcgcacgccg ggttcctgct gaccggcgtc gtcgccacgt ccaaggacgg cctgtccggc
     9421 tcgctgttct acctcgcggc ctacggcttc accacgattg gcgcgttcgc cgtgatcacg
     9481 atggtgcggg acgcgggcgg cgaggcggcg cacctgtcgc gctgggccgg gctcggcaag
     9541 cgctccccgg tcgtcgcggg caccttcgcc ttcttcctgc tggccttcgc cggaatcccg
     9601 ctgaccagcg gcttcaccgg caagttcgcg gtgttcaagg cggccgtgca ggcggacgcg
     9661 acgccgctgg tgatcgtcgg tgtgatctcc tcggcgatcg cggcgttctt ctacgtccgc
     9721 gtgatcgtcg tgatgttctt cagcgagccg gaggcggacg gaccgacggt cgtcgccggc
     9781 ccggcgaccg cggcggcggt ggcactcggg ttgacggcta ctgttgtact cggtgtgctc
     9841 ccccagccga tcctggacct cgcggggcac gcaacgacac atatgttcgt ccggtaaggg
     9901 gtcatgggtg agcaacgcct tcgctgagga gtccgggcag gtctctggtg gggggagtgc
     9961 gcccccgcag gccccgcccg aggagaccgg cccgttcggc ctgcacgtcg acgcggcgct
    10021 cgcggccgac gccaagcgcc gcctcgccgc cgtggaggcg ctcctgctgg agtcggtcca
    10081 gggggaggac gcgctgctca ccgaggcgtc caagcacctg gtcgtcgcgg gcggcaagcg
    10141 gttccgcccg atgctggtgc tgctcgcctc gcacttcggc gaccccgccg cggccggcgt
    10201 cgtcccggcc gcggtggtgg tcgagctgac ccacctcggc acgctctacc acgacgacgt
    10261 catggacgag gcgaccgtcc ggcgcggccg ggagtcggcg aactcccgct ggaccaacac
    10321 ggtcgcgatc ctcaccggcg actacctgtt cgcccgcgcg tccgacctgc tcgccgacct
    10381 cgggcccgag gccgtccgca tccaggcccg cgcgttcgcg cggctcgtcc gggggcagat
    10441 ccaggagacc gtcggccccg cggagggcgc cgatccgctc aagcactacc tccaggtcgt
    10501 cgccgacaag accgcctcgc tgatcgcggt ctccggccag ttcggcgcgc tgctgtcggg
    10561 cgcccccgcg tccgtcgtcg acaccgtcac ctccgcgtgc gagaagatcg gcatcgcgtt
    10621 ccagctgtcg gacgacatcc tcgacatcga ctccgacgcc gagcagtcgg gcaagacccc
    10681 cggcaccgac ctgcgcgagg gcatccgcac gctgcccgtc caccacgtcc tcgcggggac
    10741 cgacgagaag gacgcccggc tgcgggagct gctcgtccag gacctctccg acgacgacgc
    10801 cctgcacgcc gaggcgctcg cgctgctgcg cgcgcacccc gccatggacc tcgcccgcgc
    10861 cgacctgcgc cgctgggccg aggacgcccg cgccgagctg ctcacgcttc ccgacatccc
    10921 cgcgcgctcg gccttcacgg gcctgtgcga ctacgtcgtc tcccgcacgg gttgaggcct
    10981 gctcgtcaga cgctctgggt ctcggtgagg ccgcgcgact tcatcgcgtg caggacgagg
    11041 tcgatcagca cctgcttgca ggagccgagc tcgcgcgcgt cgcagagcat caccgggacc
    11101 ttcgggccca ggttcagcgc gagctggatc tcctccagct cgtaggcgcg ggcgccctcg
    11161 aagcagttga cggcgacgac gaacggcgtg gaccggcgct cgaagtagtc gaccgagggg
    11221 aagcagtccg acagccggcg cgtgtcggcg aggacgacgg cgccgagcgc gccgagcgcc
    11281 acctcgtccc acatgaacca gaagcgctcc tggcccgggg tgccgaacag gtagaggacg
    11341 tagtcgtccc gcatggtgat gcggccgaag tccatcgcga ccgtggtggt cttcttgcgc
    11401 tccaccccgg ccatgtcgtc gatgccgacg ctctcgtcgg tgagcagctc ctcggtgcgc
    11461 agcggctgcg tctccgacac cgtgccgacc atggtggtct tgccgacccc gaagccgccc
    11521 gcgatcacga tcttgaccgc ggtggggagc cggcgggcgc gtacctcccg cctagagggc
    11581 ccggagtcca tcgatcaccg ccttgtagag cctgatgtcg tgcatgtccg cctccggttc
    11641 cggttcctgg agcgagacga accccttgtc gaacaggtcg cccagcagca cccgcacggt
    11701 cgcgaccggc aggtcgagcc gcccggtgat ctcggccacc gacagtaccg actggcacaa
    11761 ccggatgatc gccagatgct cggggccgag cccgatcgcg ccctccggct ccggaccctc
    11821 ggccaccacg agcgtgatca ggtcgaacct gccgcgggtc ggctcgatcc gcccgctggt
    11881 catcacgtag ggccgcacca tcggcccggt gccctccgcc aagagcctcg ggtcctggac
    11941 gggcggccgc ggcgccggca ccgcgggcgg cggctcgtcc cgccagggat cgagcgggtg
    12001 ctcctcgggc ggcatcatga ggtgcgtccc tccgcggcgg cctcggtgcg ggcgggcgag
    12061 ctgaggtgct ggcccatcgc ggtcacgagc atcgccatct cgtaggcgac caggcccaca
    12121 tcggcctcct cgccggccag caccgccagg caggcgccct tgccggccac cgtcaccagc
    12181 atgaaggccg actgcatctc gatgatcgtc tgccgtaccg ggccgccgcc gaagcgggtc
    12241 ccggcgccct tggcgaggct ctggatgccc gccgagaccg cggcgaggtg ctcgccgtcg
    12301 tcctgcgtca tgcccttgga ggaggccatg agcaggccgt cggccgacag cacgaccgcg
    12361 ctgcgggtgt gcggcagccg gtggaccagg tcgtccagca accagcccag atcggatgaa
    12421 ggacccgtct tctgcatcac tggccttcct cgccttcctc tgcgtgactg ccgagggcac
    12481 cggatgcggc agcggacgcg gcgccggccg gggcgccgtt cgcggcaccg gccgcgtccg
    12541 tgcggccgcg gcgggtgccg cgctggtacg agcccatgat ctgcttgatc tcctcgggcg
    12601 agcggccggg atcgtcctcc tcgtccggcc gtccggcggc gtccgcctcc ccggtccgca
    12661 gcggctcggc gaggttcgcc tgcggcaccc ggacgggcag accggacggt gtcgtggaga
    12721 tgtcggccac gggtgactgg tcctccgcct cggtggtcgg gacttcggtg gtggacgcgt
    12781 ggtgcccgcc ggccaccgcg gcccgccggt aagacgaagc ccgccggaag gacgaagctt
    12841 gccggtaagg cgaagcgacc ggcacaccac cgcggagagc cgtggccccg gcccgcggac
    12901 acgcgtcgcg gatgcgcatg acaacccgtc ccaacgagat cgaacgggac cgtgccaccg
    12961 gccggtgaag ctaccggcgg tcgcggggcc ctcggtgtcc aggtgtgcgg cgcggccggg
    13021 cacacggcct cgcggccggc tccccgccct gcggccggga acacggcctc gcacaccgca
    13081 gcaccttagc aacgcctgtt cgccctaagg cgtcaatttt cactatttga aggggttatt
    13141 tgtgcggcga ctactgagag ccatgtggca aagttcactt aaaagtttca gataggtact
    13201 tgcgcaccgc gctcgctctc taacgcgcga ggtgaagtgc cgcgaggacc gtcccgcgga
    13261 caattgcccg tggcaggtaa aggtccttat cgtgccagag cggcgggtcg gacgtccggc
    13321 cgctgaagcg ttccaaccag gcgcggcccc ggaccgccgc ccccaccgac gggatgctcc
    13381 gcgacattcc cgccatggcg ccgcggccga gcagcaacgc ctgcacggcc tgcgcggtct
    13441 cctcggcggt gccgtcccac agcccccagg agccgtccac gcgctgggtg tccaccaccc
    13501 agcgcagcgc gcggcgcacc ggctcccggg ccgcctcgcc gccgaagctc cgcagcgcgg
    13561 cggtcgcgca ggccgtcgcg tagtacggcg agacatgcca ccggtcggac cagctcccgt
    13621 ccggccgctg ctggccgagc agccagctcg ccgccttcgc gatggcgcgc gcgtaccggg
    13681 gcgccgcggc gggacgggac ttcacgtact gcccgaacgc gtcgagcacg tgcgcgttgg
    13741 tcgtgacgga ggccccctgc tcgccctgcc aggtgcagaa atgctcgtcc aactcgaagg
    13801 cgagcaggct gtcgggctcg tgcggcgcgc cgaggagcgc cagcgtgtag agggtcacgg
    13861 cggtggtgtc ggcgtccgcg ggcaggccct ccccggccgg cgtgccctca ggcccgagcg
    13921 ccgccgccag ttccttccgc tggccctcgg gcacctggat cggcaccccc gcccggaccg
    13981 ttccgctcag cgtccacgcc tgctcgaaca cggtgatggg caggccgcac gggacgggcc
    14041 cgccgtggag tcgcgcggcc cgttcgagga agcggcgcgc ccggtcgccc ggcggcggga
    14101 cgctgccgcc cagccaggcc gcggtggcgg cgggcgacgc cccgaccgcg ccggtgcgcg
    14161 gccccggcga cacgctcgcc gatccccgcg ccgcgggccc ggcgatctcc agcgcgtgga
    14221 ccatcttcgt ggggacgctc cgtccggcgg cgatccgggc gcggatcggt tcgaggagcg
    14281 cgccgtccca gccgtggggg aggcttagcc gggccccgcc cagccaggcg tccaggccgc
    14341 tgatcggcgc ggcgtcgagc gcggcgagat gcccgttgag cagctcggtc aggtacgccg
    14401 agatgagctc gatggcgggc atgtcgggga ccggccgccc gcgcccgccg gtgaggaggg
    14461 cgtccgccgc gcgcaggccg cggtccgccg cccgcgccag cacctgcggg tccaggccgc
    14521 tgtcgcgcgc ccgcagcgac gacaggacgc cctcggtcgc gctcagcgtc gggacgatcg
    14581 cgtagccgtc ccgcgctccc cagccgccgt cctggcgctg cgccgcgagc aggaaccgga
    14641 gccgctcctc gtgcccggtc agccagggcg cgagggacac gaggcgtccg gtctcgtaca
    14701 ccgaggggga gacctgcccc cagggctcgc tggtcagccc ggcgacgagc gcctgcgcgc
    14761 ccgccctcgt ccgggccgcc gcgccggtgg ccggtgcccg gtccgcttcg gcgagggcgc
    14821 agcccccgcc gcgtccattg ccggccgaga tttcacctgt ttcttcgcct gcggttccca
    14881 tccggctacc tcccgccaac cgatcgcggc gcggttttcc aaggtccgcc gaattcgcgc
    14941 gggaaccggc cctgaggggt gaagcgtttc agcccgctct ttcggccacg gaacggccgg
    15001 cgcgggcgcg gggtgggtcg ggtccggggt acctggcggg tgcggaaagg ggcgatgcca
    15061 atggctacgg gcattctcgg ctgtccctct tcggatgggt ggcacatgct gagccgtggg
    15121 gaggcttgaa ggtggacgcg cggaccagga gcgggaggtt tgttcgatta tgcgaagtaa
    15181 gcgctgtgtg agtggttccg ctgaagtatc acatgatcac ttaacgtaaa caaggggcgt
    15241 tagggtagga aatctaccta tttgcgcgtg atgtagctca ctttgcaaga gattcgtcgg
    15301 tgcgctacgc gaaagctcga cgactcattg atgacgctga gttcaagatc ccgaacactg
    15361 ggcaatcagg gactggaact atcgaattcc cattcgacga cacgagcgct caggaatcga
    15421 aaaagcgggc gcccggagaa tggtttacag gccgtcggaa gtggggagaa tagcgggcca
    15481 ggcaaggccg ttggaaacct tgaacctgcc ggtgaccgtg cgggcgccgc agcgcgccgt
    15541 gatcgtgtag tggcccggct tggcgtcccg ccggacgctc gcgacgccct cgccgtgatc
    15601 ggccttgccg cgcagcgcga tctgcctggt gaacgcggga gagaccgcct cacgcggctg
    15661 cgcgcaccgc ggcaccgaca cctccacccg ctggccgggc cgcgccacgc ccggctcgac
    15721 cgagatctct ccgcgtccca tgccgctggc ctgtcccgcc gcgggcgccg cgagccccgc
    15781 gatgacaagt ccgcttccca acatggtgac gctgagcagg cgcaacgggg gactcctcgg
    15841 ccaggagggg atgtgacgtc cggcactcta gtacctctag gcggcctcgg acacaggctc
    15901 cggaatctgc ggcgcccgcc gggcggcgtt cagcccgtcc caggtcaaga caatgagcgc
    15961 gagccatacc agaaggaagc ccgtccagcg gctcgcgggc atctcctcgc cctgcacgag
    16021 caggccgatg aggaactgga gcgcgggcgc caggtactgg agcatgccga tcatgctcag
    16081 cggcagccgg atcgccgccg cgttgaacag catcagcggg acggccgtga ccagccccgc
    16141 cgtcgccagc aggaccgcgt gccccgtgcc cgcgtgcccg aacgccgcgt cgccgcgtcc
    16201 ttccaggacc aggctgacca cgagcgcggg cacgaacatc gccgccgtct ccacccccag
    16261 gctctcggcc gagggcatgg cggcgaactt cttcagcagc ccgtacgtcc cgaaggagaa
    16321 cgccaggatc agcgcgatcc agggcggctc cccgtagtcg gcggtcagca gcacgaccgc
    16381 cgccgcaccg agccccaccg caccccactg ccaggcccgc aaccgctccc ggaagacgac
    16441 gacgccgaac accacactga tcagcgggtt gatgaagtac ccgagagcgc cctcgatcgt
    16501 ccgcccgctg ttgaccgcgt agatgaacac gccccagttg acgctgatcg tcacagcggc
    16561 cagcgtcagc agtccgatcc gccgccgccc cagcgtcctg atccaacccc agttccgctt
    16621 gaccgcgagc acgaccgcca ccgtgaccag cgaccacatg atccggtggg ccaggatctc
    16681 ggccgccccc gccggcttga gaagcggcca gtacagcgga aacaaccccc acagggcata
    16741 cgccccgact ccgcacagta cgccccgttt cacgccccgc acgatagcag cgcggtaatc
    16801 acccaccacc actcaggctc atgtcgccga ggccgagcta cattggatcg tatgttcgcg
    16861 aagacccagc tggtcacccc ggagaacgcc ctcccgggca gggacacgcc actcccggtc
    16921 ccgccccgcc acgaggtcct ggacgcaccc ctggcgccgc ccttccccgc cggcaccgag
    16981 atcgcggagt tcgccctcgg ctgcttctgg ggcgccgagc gccgcttctg gcagaccccc
    17041 ggcgtcgtct ccacgtccgc cggctacgag ggcggccaca ccccgaaccc cacctacgaa
    17101 gaggtgtgca gcggcctcac cggccacacc gagaccgtcc gcgtcgtcta cgacccgtcg
    17161 aaggtctcct acgacgacct cctccgcgtc ttctgggagt cccacaaccc cacccagggc
    17221 atgcgccagg gcaacgacgt cggcacccag taccgctccg cgatcttcta ccgcaccgac
    17281 gcccagcgcg cggcggccga agcgtcccgc gacgcctacc aacccgtcct caccgccgcc
    17341 ggccacggcc ccatcaccac cgaactgacc cccgcgacga ccttctacta cgccgaggac
    17401 taccaccagc agtacctctc cgacacgaag aacccgaacg gctactgcgg cctaggcggc
    17461 accggcctct cctgccccgt aggcgccgcc ggcaccacta gctgatccag cacccgagct
    17521 gactccgcgg cctgcgatgt tgtagacacc cgcgatgggc tcgcctcgcc ttcgcggccg
    17581 cggcgttcta cgtcgatcta ctcgctgacc aggggtgttg ctaggggagc cgtacacgcg
    17641 tcagctccac ggcaagttgc gagagttgcg cttctatctc ggtaccgagg ccgtgcgagt
    17701 gacctactgg atcgctccgg gcaagcggtt catcctgcta acggtcttcc acgagacgcg
    17761 tatgcgagaa gtggagcggg ctcgccgggc attgcggctg tgcgtggccg aagcgcacat
    17821 ggtggacgct ggggagggga gaggtcgatg ggtggccggt ccgactgggg tgagctgcgg
    17881 gaacgccgca tgggcgagcc cggcgccgtc gaggcctacg ccgctactcg cgtggcctac
    17941 gagctgggac gtaccgtccg ctccctgcgt gaggagcgtg ggtggagcca gagggagttg
    18001 caggggcagc ggagatgacg cagtccgccg tggccaggtt tgagaccggc ggcactatcc
    18061 cgactctgct cgtactcgaa cggctggcga aggccctcgg agccgaactc gtcgtccagc
    18121 tacggacccc cgccgcatga cctgagcgtt ccggcggtgg tcggggcggg tcagactttc
    18181 agccagtcca cgggggaggg gcggtcggcg ctggcggtct tgcacagggt cgggatgtgg
    18241 gaaccgtcgc tggagacgac cttggcgggg ccggtggcgc tcgcggcggt ggccacgacg
    18301 agggcgtcga tcacgcactc gtggccggag agccccgtgg agtccagcag ggcggcggcc
    18361 gcgtcggcga tgtcctcggt gacggggacg atcgtgagcc tggaacggag ccatgccagc
    18421 cgtttgcccg cccggtcggc gcggcgttgt tcggcgacgg tgacggcgct gatcactggc
    18481 atgaactcct ggcgcacggc gagttccaga cgtgcggtca tgcgccggtc gtcgtcggcg
    18541 aggagcgaca gcccctgggc gtccaacacg aaggcggggc cgacgagggg cgagccggtc
    18601 actcgcctcg ccacgcgaac tccgcctcgg ccagttcctc cggcgtgaac tctccgtgcc
    18661 gcgcgacgtg atcgtcgacg atctcctgtg ccttgagcag ggagagatgg cgctcggccg
    18721 cggcgtccag gaactcggag aagccacgcg cgccggtacg ggcctcgatc tgctccacga
    18781 cggactcgcg gagggtgacc gacttcttga cggtcttgcc gtagcgtccg ccggtggctc
    18841 ggcggaccct tcgcccgggg gagcgctgct ccgggtcacg ggtgtctgcc atggtccaac
    18901 tgtactactg aaagtaggat agttgtgggg gcggcgctgg ggggcgccgc ccctgggtca
    18961 ggtggtcagg gattttgagt cggggatctg gtggacgggg gttcgggtct cggattggcg
    19021 gcggtcgccg ttggtccatt ggaaggccca ttcggcggac atcagggcgc cctcctgcca
    19081 gccggggagg ggggagacct ggtcgccgat caccaggaac ctgttgttgc cctgggggta
    19141 gatcagggtt tggtagatgc gtttgtggtc ggggatttcg gggtcccagt gggcccagcc
    19201 gtgctggatg taggggacct tctgccaggc gatggagatg gccttctcgt cggggacgat
    19261 ggcgcggctg aggaattcct ggtggagttt cgcgccggcc tcgcgggcgg tggccaggcg
    19321 ttggaggtgg gtctgctcgc ccagttggcg gccggcgtcg taggaggagt aggcgccggt
    19381 cagggtggcc ttgccggggg cgaagcagtc gttggagggg tagacgatct ggcgggcgag
    19441 gttgccgagc cagctgatgc cgccgtagat ctggtagcgg tccgactccc agaagcgctg
    19501 gctgacctgc cagccgacct tgacggcgcc ggagttctgc gcgttctcga ccgcccaatt
    19561 gaactcgggt gagaagcctt cgaggtggac gcgctgccgc agcaccggta tcgggatgct
    19621 gctcaggcag tggtcgaagg tcttgtcgtg cgttccgtcg gcgtcccgcc aggagacgcg
    19681 gacgttgtcg tcggtgagtt tgatcgcgtg gacgggtgcg ttcagtgtga tgattccggc
    19741 gggcacggtc ttcgcgatgg aacggacaat ggcgtccatg ccgccgaccg cctggaacat
    19801 cgagttctgc cagacgatgt cgtcgccgcg gaagaactgg tcgttccaga actcgctttc
    19861 cagtagggcg atgaggggca gcggggcgac gccctcggcg gcctgcggga cgccgagggg
    19921 cttggcgagg ccggagcggg tggagccgtt gaaggcgtgg tcggtcttgt cgagctggcc
    19981 gaactccgtg aggaggatca gcagtttctc gcgctgggag tcggtcagct tgtcgctgtc
    20041 gagcaggccc ttcttgacgg cggcggccgc gtattcggcg acgtatccgc gggtgtcgaa
    20101 ggcgatctgg cggtaggtcc tgctcgcctt ctggaaggcc ttgtcggtct ggtagaggtt
    20161 ggcggtcgac tgcatgatgt agggctcgag cggaatgtgg aaccggcggc agagcgcgaa
    20221 cacgcgctgg tgctggtggg agagccggct cggcccgatg ttgaggtaga ggccctggtc
    20281 gaactggcag gtcagggtgt gggacgagcc gtccgcccac acttcggtga tcgtgtcgcc
    20341 gcggcgcagc gtgcgggcgc ggccgttggt gcggtcctgg gcctccagga cggtgaccgc
    20401 gtagccggcc tggtggagtt tgacggcgac cgtcattccg ctgacccccg cgccgaggac
    20461 ggcgacggac ctgccgctgg cctttctggt gggcggggtg aaaaggccgg tgggcgcggg
    20521 ttcggcatgg gcggggagtg cgccggtcat gacctggagc aggccggcgg aggccgccat
    20581 gcccaggaaa ttccggcgtg aggacccctt ggctgaattc tccattgtgt tctccttggg
    20641 agcgaaaccg acgaggtgcg gtagggctgc cggaggaggt cgggggcgag gcatgggggc
    20701 gggtacctat ggcgcggttc gcgtcgcggg catgcgcgca gggtacgggg cgcgggtggt
    20761 ccgaaccatg ggcgcggacg gaagcggcca cgtcctggca gccttttcct cgccttgaag
    20821 tcgaccgttt tcggtcttcg gttgtatgga gttcttgtta ccggagttcg cagcgggggc
    20881 gccggggcga ccgtgttcag ggtggctgtg gatttccggt caggggccta tgggcgagat
    20941 tggccgtaga tgtggacgcg ctggctgcgg taggtcgtgt cgcggaggtg cgtgtggccg
    21001 atccgggtcg cgacggcgat ggagcggacg ttggacggca ggatcaccga gatcacctcg
    21061 tccgcgccga gctcggtgaa gcagtaggcg acggcggcgc ggcccgcctc ggcggcgtag
    21121 cccttgcccc agtggtcgcg ggccaggcac cagccgacgc cgaggccggg gaagccgtgc
    21181 gggcgccagg ggccggcgcg tccggcgaag cgtccggtgg acttctcgac gatcgcccag
    21241 tgcgagtagc cgcggatctc ccggtggccg atgaaggtgg cgaggctgcg ccaggcgtcg
    21301 gcgggggacg tgccgacgga ttcggccagc ccgcccgtga cgtccgggtc ggcgagcatc
    21361 gccgcgtagt cgtcgaagtc gtcgcccgtc agcggccgca gcagcagccg ttccgtctcc
    21421 accacgctca tgatcacagt gtgcacgggc cgtcaatggc gcagagcctc cccttggtgg
    21481 gaaggccctg cgtttcgcgc tttccgcggg aggcggagta tgtctctagc ggtggacggt
    21541 gcgttcgtca gtacggcagg aggcggcccg aaggcgtcct caggtcgggc gggctcggtt
    21601 gacgtggggg cttggggctc ttgatgagct gctgccgtgc catggtgatc atctcccccg
    21661 tcgggccggg tgttaacccg ttgatcgagc cgatgtcgcc tgcacttgta cgacgcgcca
    21721 gctgtacgtg aggttcgccg agcttttgct ccaactctgc cctttcgacc gaatttcgct
    21781 tgcggagcgt ggtcaaaggc gcgtggccga tcacggtcag gagacggttc acggtcagga
    21841 gacgatgtcg cggttgcgga agcggcggaa ggcgagggcg aacaggacgg ccgtgtagga
    21901 gagggagatc gcggagccct tcgccatgcc ggtccactgg atctggggct ggagggcgtc
    21961 catccacgag tacatccagt gggtgggcag gaagtcgcgc caggagccga gcgcggtcac
    22021 cgcgtccagg atgttgctga cgatcaccag cccgaccgcg ccgccgaccg cgccgagcgg
    22081 cgagtcggtg gtgaccgaca gcaggaacgc cagcgcggcg acgacgagct gggcgaccag
    22141 cgagtagccg atgatgatcg ccatccggcc gagcgcggtg cccgccggga cggtgccgcc
    22201 cgtcggcagt tcgaccggcc cccagccgaa cccgacggtg cccgcgacca gcgccatcag
    22261 tgggaggctg acgaccgcga cgacggcgta ggacagcgcg accgcgagct tctgccgcag
    22321 cagccgggcg cgcgggacgg gtgcggcgag caggtagcgc agcgacgacc agcccgcctc
    22381 gctcgcgacc gtgtcgccgc agaacagggc caccgcgacg acgagcagga agccggtcga
    22441 gacgaacagc gcgaacagcg cgaagttgag cgcgctcgcg gtggcgacgt cgaccaggct
    22501 gggcacgccg tccggccccg gatcgccgcc gatcttgaac gcgccgacca gcacccacgg
    22561 caggacgagc aggatgccga acgcgaccag cgtgcggcgc cgccggaact ggcggatcgc
    22621 ctccacgcgc agcggcagcg tccgccggac gcggtacccc gagccgcccg ccgcggcggc
    22681 gcccgagccc ccctcggtgg cggtgatctc tccggtggtc atggggcctc cccgatgatc
    22741 tccaggaacg cgtcctccag ccgccgcccg gacccggtga tctcggcgac gggaccggcg
    22801 gcgacgcggc gccccccggc catgacgacg gcgtgcgtgc aggtctgctc gacctcggcg
    22861 agcatgtggc tggagacgat gacggttcgc cctccggccg cgtaccggac gagcacctcg
    22921 cgcatctcgc ggatctgcgg cgggtcgagg ccgttggtcg gctcgtccag gacgaggagg
    22981 tccgggaggc cgagcatcgc ctgcgcgatc gcgaggcgtt gccgcatgcc ctgcgagtac
    23041 gtccggacgg cgcgctccag ggccgatccg aggtcggcga tccgcagcgc ctcgtccatg
    23101 tgggcctcgt ccaggggacg cccggtggcg cgccagtaca gatcgaggtt gtcgcgcccg
    23161 gagaggtggg ggaggaaccc gggcccctcc acgaaggacc ccagccgcga caggacggcc
    23221 gctccgggcg tgacacggtg cccgaagatg cggatctcac ccgagtcggg gtggatgagg
    23281 cccatcagca tgcggagtgt ggtcgttttc cctgcgccgt tggggccgag cagcccgagc
    23341 acctggccct tctccacgcg gaatgacaga tccgccacgg cgaggtgacc gttcttgtac
    23401 ttcttggtaa ggccgcttat ctccagcggg acgtcgctca acgacggctc agaggcccgc
    23461 ccgcgccgtc cgcgcaccag aatcccggcg gccacaccca gcgcgacgag cggcagcacc
    23521 cagacccacg ccgggatcgg ggcgggctcg gtcttcagcg ccggaacggt cgggaccgtc
    23581 agccccgaca ccacccgcac cttgtacgag gcgggctgcg gcggcgtcgc gaaccccatg
    23641 tcggtggtgg cgaggacgac gcggagccgg tggccgcggt cgaagcggta gtccatcgcc
    23701 gggagcgtga ccgtggcctc gccgccgggg gtgacgcgca gcggcgcggc gatccgccgg
    23761 gccgggacgg agattccgcc cggcgacacg tcgtacagct tggcgaacag ggggaccggc
    23821 cccttgccgc tcaccgcgat ccggacggtg gcggcgccgg tcagccgcag tgggctcgcc
    23881 agcggagcgg tgtcgaagtg ggcggcctgc cccggcatgt cgatcggcag ccccgcgccc
    23941 agtccgcccg cgagcccgcc caggtcgccg aggtttccga gcgcgccgag gccgggcagc
    24001 gccgagatcg acgcgggcgc cccgcccgcc gggttgaaga ccgtctgctc gcgcccggcc
    24061 agcgggagcg agcgcggccc ggcgccgagc cccgggtacg cgcgggaccg cgcctcctcc
    24121 acgacgacct gctgcgtgga cgagtcgagc ccgcccgcgc gcgtcaccgc gaagccgtcc
    24181 tcaggcaacg aaccattccg gagccgcgcg tcgaagaaat cgtgcagcag cccccggatg
    24241 cggtcggtct cggagtcgcc gccgtcgtgc ccgccctggt accagacgac cgacaccggc
    24301 gcgccgttgc gggcgatgcc gcgcgcgttg gcgtccgcct ggtcgagcgg gaacagcgag
    24361 tcggcctgcc cctggaccag cagcgtcggc accttgatct ggccgatgac cgacgacggg
    24421 ctcgacctgc gcagcgtcgc caccgcgtcc gccgtgggag cgcccgtctc ggcgaccttc
    24481 tggtacatct cgcacaggga cggcaggaag cgcccgcatg cggaactgcc cgcgccgtcg
    24541 gtgaagaaca ggcccgccca cagcttcttg aagacgcccg tctgggcgcc cccgcctgtt
    24601 gcgttgggga acagcgcgtc ggcgaggtcg ttccaggtga tctgcggcgc gatggcgtcc
    24661 acccgccggt cgtaggcggc ggtcatcagc gcgatcgcgc cgccgtagga ctcgcccgcc
    24721 atgccgagcc gcgggtcgcc ggggccgtcg agctgcacct cgggacgttt cgccagccag
    24781 tcgatgagct gccgggtgtc cttgacctcg tagtcggggg agttcagcgc gatctcgccg
    24841 gtggagcgcc cgaagccgcg cgccgaccac gcgagcaccg c
//
