LOCUS       NZ_JAICDG010000001     31451 bp    DNA     linear   CON 29-AUG-2024
DEFINITION  Actinomadura terrae strain OS3-83 contig1, whole genome shotgun
            sequence.
ACCESSION   NZ_JAICDG010000001
VERSION     NZ_JAICDG010000001.1
KEYWORDS    WGS; RefSeq.
SOURCE      Actinomadura terrae
  ORGANISM  Actinomadura terrae
            Bacteria; Actinomycetota; Actinomycetes; Streptosporangiales;
            Thermomonosporaceae; Actinomadura.
REFERENCE   1  (bases 1 to 2300701)
  AUTHORS   Lee,S.D., Yang,H.L., Kim,I.S., Choe,H. and Kim,J.S.
  TITLE     Actinomadura terrae sp. nov. and Actinomadura litoris OS3-89,
            isolated from rhizosphere soil of cactus
  JOURNAL   Int J Syst Evol Microbiol 73 (1) (2023)
   PUBMED   36748505
REFERENCE   2  (bases 1 to 2300701)
  AUTHORS   Lee,S.D.
  TITLE     Direct Submission
  JOURNAL   Submitted (15-FEB-2022) Institute of Jeju Microbial Resources, BioPS
            Co., Ltd., Sancheondan Dongil 16, Jeju 63243, South Korea
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: SPAdes v. 3.13.0
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 141x
            Sequencing Technology             :: Illumina
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_022751215.1-RS_2024_08_29
            Annotation Date                   :: 08/29/2024 06:12:19
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.8
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 8,085
            CDSs (total)                      :: 8,002
            Genes (coding)                    :: 7,936
            CDSs (with protein)               :: 7,936
            Genes (RNA)                       :: 83
            rRNAs                             :: 5, 4, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 3 (5S)
            partial rRNAs                     :: 2, 4, 4 (5S, 16S, 23S)
            tRNAs                             :: 67
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 66
            CDSs (without protein)            :: 66
            Pseudo Genes (ambiguous residues) :: 0 of 66
            Pseudo Genes (frameshifted)       :: 13 of 66
            Pseudo Genes (incomplete)         :: 56 of 66
            Pseudo Genes (internal stop)      :: 3 of 66
            Pseudo Genes (multiple problems)  :: 4 of 66
            CRISPR Arrays                     :: 4
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 21:31:58
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 1784906
            Orig. end                         :: 1816357
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            JAICDG010000001.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..31451
                     /candidate_cluster_numbers="1"
                     /candidate_cluster_numbers="2"
                     /candidate_cluster_numbers="3"
                     /contig_edge="False"
                     /product="lassopeptide"
                     /product="ectoine"
                     /region_number="5"
                     /rules="(PF13471 and Asn_synthase or micJ25 or mcjC)"
                     /rules="ectoine_synt"
                     /tool="antismash"
     cand_cluster    1..31451
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PF13471 and Asn_synthase or micJ25 or
                     mcjC)"
                     /detection_rules="ectoine_synt"
                     /kind="neighbouring"
                     /product="lassopeptide"
                     /product="ectoine"
                     /protoclusters="1"
                     /protoclusters="2"
                     /tool="antismash"
     cand_cluster    1..22577
                     /candidate_cluster_number="2"
                     /contig_edge="False"
                     /detection_rules="(PF13471 and Asn_synthase or micJ25 or
                     mcjC)"
                     /kind="single"
                     /product="lassopeptide"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..22577
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:12577](-)"
                     /cutoff="10000"
                     /detection_rule="(PF13471 and Asn_synthase or micJ25 or
                     mcjC)"
                     /neighbourhood="10000"
                     /product="lassopeptide"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..12577)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="(PF13471 and Asn_synthase or micJ25 or
                     mcjC)"
                     /neighbourhood="10000"
                     /product="lassopeptide"
                     /protocluster_number="1"
     gene            540..1763
                     /locus_tag="K2F47_RS08005"
     CDS             540..1763
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019630649.1"
                     /locus_tag="K2F47_RS08005"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="SLC13 family permease"
                     /protein_id="WP_242902114.1"
                     /transl_table=11
                     /translation="MPSPPAALRRAVRSVGVLDRVRAGLLALGLLFVATGLLPPATARD
                     SVERIAPLLLFLLSVIVLAELTKEAGVFDAIAQRMARAGRGNYVALFLLCVGFASVNTV
                     FLNLDTTAVLLTPVMLALAARARIAALPLAMTTVWLANTASLLLPVSNLTNLLAADRVA
                     LETPAFAARMWLPQVAVLAVTMLLLWVFFWRRGMRGADSYDPPDVAPVRDRVLFSATGV
                     ACLLFIGAILAGVHTGLQLGLAATVAAVVAVAAFAVRDRSALRGELIPWRLMVFVTGLF
                     LVVPTLERYGLDEVMRSLVGGDDGVAGAARAAFAGAGLSNVLNNLPAYVAGESAVPESN
                     RDQLLSLLIGTNVGPVITPWGSLATLLWFEWCRRWDVRVPMRKFVITGTVLAVLGCAAA
                     VAALLVTR"
     gene            complement(1782..2675)
                     /locus_tag="K2F47_RS08010"
     CDS             complement(1782..2675)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1207: inositol monophosphatase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012889676.1"
                     /locus_tag="K2F47_RS08010"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="inositol monophosphatase family protein"
                     /protein_id="WP_242902115.1"
                     /transl_table=11
                     /translation="MRSTPPSPALPVDLCEARRVAVEAAEAAGALVRAGTGGPLVARPK
                     GRNGDVVTELDTAAEELIVGRLRTAYPGHRIIAEESGVLDGADGAHLVWLVDPLDGTNN
                     VAIGMPVYAVGLALCAGTIPVLGVVHDPVSGRTWTAVRGEGALDPDGAPLSLAPRPRPG
                     RERNPVLGWTQGHAVKAGDPSAFALRSALELRCSRLLQLWAPLVAWAMLARGDIDGIVG
                     YQPELVDLPPGALLAAEAGAELRRLDGGPYELSIDRPPSELGFVAARPELLARLVETAN
                     RALDVAGPDGQIPLVR"
     gene            complement(2737..3444)
                     /locus_tag="K2F47_RS08015"
     CDS             complement(2737..3444)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012889677.1"
                     /locus_tag="K2F47_RS08015"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="hypothetical protein"
                     /protein_id="WP_242902116.1"
                     /transl_table=11
                     /translation="MRYEEIRREIEAGTAARTLPAWAGRVLADVAAGRSRVPAVRHPLG
                     FLCLPVERSGDFGVCLHIWTSEVDSAPSTTSPVHCHSWDLLSFVLYGTVRNVRMDVGGG
                     SGGAAAQVFEVVSRGEVDELRATGRTVRYSPGRSTAHGTGESYTLPAGVFHSTLIEDGR
                     DAATVALGRQTPGSGDLSLGPLDVATHQVRRARSEPDEAARALHRSARAVANAHPAPPG
                     EGCSLGGLSPTRR"
     gene            complement(3509..4522)
                     /locus_tag="K2F47_RS08020"
     CDS             complement(3509..4522)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020543765.1"
                     /locus_tag="K2F47_RS08020"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="hypothetical protein"
                     /protein_id="WP_242902117.1"
                     /transl_table=11
                     /translation="MTRFATWLGKNADAFIALVLAITVAVLGVGVDLPHEDEITNSAIL
                     AVVGLLATSVLRDRGRRVPVEAEVRDTLRASSTTLDELSGRLSHIEAFEGVLADTKRAL
                     DETTIVRVISGAQVAQVLEEARRDTDRWIFKGGTGTYIRAKTLPETVAAARRDGRTLLF
                     RLEIIDPTDVEVCEAYARHRRSSADGPDGTGEPWTLERTRKEAYATILAACWHKQRFGM
                     LDIDIGLARTMTTLRYDLSSSLIVVTRDNPRGQALVVDSTKFYYSWLSAELLTSLDQAR
                     RVPVEHARLAPLDDEPTVEQVRRLYEVIGIDMAQGYTDRDVIEIIRKALRPKDPYE"
     misc_feature    complement(4524..4535)
                     /note="TFBS match to CcpA, Catabolite control protein A,
                     confidence: medium, score: 17.15"
                     /tool="antismash"
     gene            4709..5863
                     /locus_tag="K2F47_RS08025"
     CDS             4709..5863
                     /GO_function="GO:0000155 - phosphorelay sensor kinase
                     activity [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1048: sensor
                     histidine kinase"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019630646.1"
                     /locus_tag="K2F47_RS08025"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="sensor histidine kinase"
                     /protein_id="WP_242902118.1"
                     /transl_table=11
                     /translation="MQLRGWWSAGWPTPRSRALDLTLAVSLAVVDGVFLWFAPQDFWLP
                     PPVTSAGSFLLGLGLVFRRRHPVRLALLAVALGTVAGAGVFALVVILYSLAAYTPNRRT
                     VWTIAAVGYVSGIAFPGPTENDDPFLAQAIFGVAFTAVPILLGLYMGARKQLLASLQER
                     AARLEREQHLLAERARGEERTRIAREMHDVVANRISVMVVHAGALKAIAVRDPGRAAET
                     ATVIGDMGRQALEELRHVIGVLRQGEEALPQEAVTLAHVRELVDQSGAAGLVVDLAVRG
                     EEQPMPPAVGRTVYRLVQEALTNVHKHAGAADTRVDLGLLPEAVEVEIANDAPTAPPDH
                     GLPSGGHGLVGLRERVTALGGSFEAGPCPDGGYAVRARLPLPAS"
     gene            5951..8068
                     /gene="uvrB"
                     /locus_tag="K2F47_RS08030"
     CDS             5951..8068
                     /EC_number="3.1.25.-"
                     /GO_component="GO:0009380 - excinuclease repair complex
                     [Evidence IEA]"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0005515 - protein binding [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /GO_function="GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /GO_process="GO:0006289 - nucleotide-excision repair
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="uvrB"
                     /gene_functions="other (smcogs) SMCOG1122: ATP-dependent
                     RNA helicase"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018657177.1"
                     /locus_tag="K2F47_RS08030"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="excinuclease ABC subunit UvrB"
                     /protein_id="WP_242902119.1"
                     /transl_table=11
                     /translation="MRPVTDLRRRVAPFEVVTEMTPSGDQPQAISELAARIGRGDKDAV
                     LLGATGTGKTATIAWLVEKLQRPVLVMQPNKTLAAQFANELREMMPGNAVEYFVSYYDY
                     YQPEAYIPQTDTYIEKDSSINDEVDRLRHSATNSLLTRRDTVVVASVSCIYGLGTPQEY
                     VDRMVRLQTGQQIERDDLLRQLVGMQYTRNDLAFTRGTFRVRGDTVEIIPQYEELAVRI
                     EMFGDEIEKLATLHPLTGEVITEDDELYVFPASHYVAGPERMERAIAGIEAELEETLAV
                     MERQGKLLEAQRLRMRTTYDVEMMRQVGTCSGIENYSRHIDGRDAGTAPNTLLDYFPED
                     FLLVIDESHQTVPQIGAMYEGDASRKRMLVEHGFRLPSAIDNRPLKWEEFLERIGQTVY
                     LSATPGNYEMSRVGGDVVEQVIRPTGLIDPEIVVKPTKGQIDDLIHEIRLRTEKDERVL
                     VTTLTKKMSEDLTDYLLELGIQVRYLHSEVDTLRRIELLRELRAGEFDVLVGINLLREG
                     LDLPEVSLVAILDADKEGFLRSETSLIQTIGRAARNVSGQVHMYADTVTPSMERAIDET
                     NRRRAKQQAYNTEHGIEPRALRKRIADILDSLAREDADTETLIGGAGRQQSRGKAPVPG
                     LASRTREVGRHAADLVGERPREELEGLIEQMTAQMHQAATDLQFELAARLRDEIKELKR
                     ELREMKEAGVS"
     gene            complement(8149..10011)
                     /locus_tag="K2F47_RS08035"
     CDS             complement(8149..10011)
                     /EC_number="7.-.-.-"
                     /GO_component="GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1288: ABC
                     transporter related protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: protein motif:HMM:NF012869.5"
                     /locus_tag="K2F47_RS08035"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_242902120.1"
                     /transl_table=11
                     /translation="MGAEDEGAPGRANTAGLRDVLRLAAGHRGAIAATVAATLLASALA
                     LAQPLVARDVIAVAGSGRTPWTAVGTLVVLFVGQALVQALVRFQLARTGEGIVLGVRLS
                     LIDHLLRLRMPVYDRHRIGDLISRADADTLALRQIIAGGLTDAVTGVIGLAATIVLMLW
                     LDWVLFGCVAAIVAGAGTALALALRGMRAASLRGRQATGEMAAGLERALSAIRTVKAGR
                     AEPRESARIGDRAEAAYVANVRMAGFDALVSPATELAVTGSFLVVLLVGGTRVAGGSGS
                     VADLVAFLLYMLYLTAPLGSIFEAFSAVQQGTGAVHRITEALALPQETDAAAAAPSEAS
                     RPLVETCGPAAPHASAHGDSSTDGGRAAALEFREVWFGYGRGRPVLRGVSFQVPPGGHV
                     ALIGRSGAGKSTIFALAERFYDPDRGEVLVEGMRADSLSRDGHRSRIGLVEQDCPVLDG
                     TLRDNLVYAAPEAGEEEIRGAVAMTNLDELVARLPKGLETRVGEHGRELSGGERQRLAI
                     ARALVARPRLLLLDEPTSHLDLESEAALHRTIDEAAGRCALLVIAHRFTTVRAAASVLV
                     LDQGRIVASGTHAELLDTSPYYRNLASQWLTTPTTPTREHARRA"
     gene            complement(10001..10441)
                     /locus_tag="K2F47_RS08040"
     CDS             complement(10001..10441)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lassopeptide: PF13471"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017559151.1"
                     /locus_tag="K2F47_RS08040"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="lasso peptide biosynthesis B2 protein"
                     /protein_id="WP_242902121.1"
                     /sec_met_domain="PF13471 (E-value: 1.6e-23, bitscore: 79.9,
                     seeds: 84, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTVPSALERPPKGPLRRRAAARLAVLLARPIALLPPARIRALLAL
                     LSRGASPATYDQAKRARDAVLAGSLACLGPRGCLPRSLATVLLCRMWGAWPSWCVGVRV
                     RPPFGAHAWVEAEGRLVEENVPDGYLAALITVPPRGGGDRGR"
     gene            complement(10438..10695)
                     /locus_tag="K2F47_RS08045"
     CDS             complement(10438..10695)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lassopeptide: Stand_Alone_Lasso_RRE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF05402"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF033530.1"
                     /locus_tag="K2F47_RS08045"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="lasso peptide biosynthesis PqqD family chaperone"
                     /protein_id="WP_242902122.1"
                     /sec_met_domain="Stand_Alone_Lasso_RRE (E-value: 1e-27,
                     bitscore: 92.9, seeds: 25, tool: rule-based-clusters)"
                     /sec_met_domain="PF05402 (E-value: 1.5e-19, bitscore: 66.9,
                     seeds: 461, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSLRLRPGVSTTDTAYGTVLLDERSGDYWQLNPTAARVLRLLADG
                     STTEEAAATMAEEFDVDEPQALRDVTALVGQLRTAGLVRS"
     aSDomain        complement(10444..10695)
                     /aSDomain="Stand_Alone_Lasso_RRE"
                     /aSTool="RREfinder"
                     /database="RREFam.hmm"
                     /description="Stand-alone RRE protein in a lasso peptide
                     cluster"
                     /detection="hmmscan"
                     /domain_id="rrefinder_K2F47_RS08045_Stand_Alone_Lasso_RRE.1
                     "
                     /evalue="1.40E-29"
                     /identifier="RREFam002.1"
                     /label="K2F47_RS08045"
                     /locus_tag="K2F47_RS08045"
                     /protein_end="84"
                     /protein_start="0"
                     /score="92.9"
                     /tool="antismash"
                     /translation="MSLRLRPGVSTTDTAYGTVLLDERSGDYWQLNPTAARVLRLLADG
                     STTEEAAATMAEEFDVDEPQALRDVTALVGQLRTAGLVR"
     gene            complement(10733..12577)
                     /locus_tag="K2F47_RS08050"
     CDS             complement(10733..12577)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lassopeptide: Asn_synthase"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1177: asparagine synthase (glutamine-hydrolyzing)"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF012936.5"
                     /locus_tag="K2F47_RS08050"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="lasso peptide isopeptide bond-forming cyclase"
                     /protein_id="WP_242902123.1"
                     /sec_met_domain="Asn_synthase (E-value: 7.5e-42, bitscore:
                     141.1, seeds: 78, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPDHDGMPGHGEASFVVLPDHEAALAVASGLPTPPERTLRHPSGR
                     PWLAGRWSDAEMTEATAGDARIAIIGTCPIGPDRLAREAGRLRDLSALDRLVRSLPGSF
                     HLVAALDGRTRVQGDAAGLRLVFHTRAGGVTVAADRADTLAALTGAALDERQVAARLLW
                     PAPHPLLHTPLWRGIEGVEPGAHLLVEPDGRASVRRWWTAPEAVRPLAAAADDIAAALT
                     AAVEARTAGGGVVSCDLSGGLDSTSVCFLAARGEAGIVASTWPGRDPADEDLTWARRAA
                     AHLPGVEHAVWPAEDSSLVYEGLLEIDDPLDEPSIGVMDRARMLDHVPRLLAKGSRLHL
                     TGIGGDHVAWCSEAHYHGLLRRRPLFALRRLRGFRALFDWPLVPAARALADGRPYRRWL
                     RDAAGDLRAPARPTVAGSLGWDMAPRLFDWVTPEAAEAARQVLREAARTAEPLAPDRGR
                     HMDLHSIRACTRIIRQWEWTSARAGLPMASPFLDDRVIEACLAVRAEDRVTPWRYKPLL
                     VAAMRGIVPDECLARANKAEASMDAADGLRAHNRDLLELCDDSRLARLGLVDGERLRAL
                     VSRPDTPALREAVLYSTLGCEVWLRTLEHRRAGAPTRR"
     misc_feature    12581..12597
                     /note="TFBS match to NuR, Nickel-responsive regulator,
                     confidence: weak, score: 20.22"
                     /tool="antismash"
     gene            complement(12596..12703)
                     /locus_tag="K2F47_RS08055"
     CDS             complement(12596..12703)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF039305.4"
                     /locus_tag="K2F47_RS08055"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="keywimysin-related RiPP"
                     /protein_id="WP_242902124.1"
                     /transl_table=11
                     /translation="MQKYETPALVAAGSFRKDTGLLQFHGNDRLILSKN"
     misc_feature    complement(12888..12908)
                     /note="TFBS match to MntR, Manganese transport regulator,
                     confidence: weak, score: 20.99"
                     /tool="antismash"
     misc_feature    complement(12979..12996)
                     /note="TFBS match to ArcA, Repressor of carbon oxidation,
                     confidence: weak, score: 14.33"
                     /tool="antismash"
     gene            complement(13247..14146)
                     /locus_tag="K2F47_RS08060"
     CDS             complement(13247..14146)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) APH"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012891210.1"
                     /locus_tag="K2F47_RS08060"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="phosphotransferase"
                     /protein_id="WP_242902125.1"
                     /sec_met_domain="APH (E-value: 6.7e-22, bitscore: 75.5,
                     seeds: 156, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIYAETPLTGVMRKAVQAGWNLPADGPAERLFGGEESAAYRIGEL
                     VVRVGPAWRSDAETEWCHAVAAHAASRMPEAVAPLRTRDGATVVRADGRPLSLWRHVEG
                     EWPDTEAPTTRAQAAALLARLHRALADYAPPPRPTRSFAEIGLDGSFPADVPELADPGL
                     DRWLADFHARTPARQVVHGDYYEGNTLARGGRLVALLDWDEAFVAAPEFEVASAALEWT
                     DEHAEAPELRRRFVADYHAAGGTAGPMDDETVAQLIRHRIRRETAYFELARARGVEHDE
                     DDLEYHRARVRAFFALKP"
     gene            14245..16407
                     /locus_tag="K2F47_RS08065"
     CDS             14245..16407
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1035: MMPL domain-containing transport protein"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF015155.5"
                     /locus_tag="K2F47_RS08065"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="MMPL family transporter"
                     /protein_id="WP_242902126.1"
                     /transl_table=11
                     /translation="MMNLPVRVARWSAGHPWRAIAGWFLFVALCLGVGISVGGHAATSA
                     DFRVGEAGRAEAMAAEGGLENRPVERVMISGEGPRDAAARDVAARMKGLPEVESVAAPV
                     RSAGGDVVRVDVTLKGPELDGRKHVEPLRAQTAGVQAAYPGLRVVETGGPSVSKGVEEL
                     RGEDLSRTEVIALPVTLLTLLLVFGSVALAVVPLLLALTSIVAAVGLSMLASHVFPDAG
                     VGTNVILLIGLAVGVDYTLFYLKREREERARAGGRLSPQAVVELAAATSGRAVAVSGLA
                     VAVSSATLFLADDVIFSSIATGAIVVTVVAVASSMTVLPALLAKLGARAERRRERRAQR
                     GKAVRARREEGAGRITTALLRPTEKRPAITLAVAVLAMLALASPLLGLKLTDMGRETHP
                     RSIPAVKAYHQLNAAFPELKSTHQVVVRADAGGAAEVRAALDDLSRRTHQDSRFTGKPS
                     LRTSADGRISLLELPVPHYGSEDAARASLRDLRKEYIPATVGRLDADVAVSGDVARYTD
                     YPDHQKGKLPLIIATLLLVTFAMTVWAFRSVVLGLVGVVLNLLSAAASLGVLVAVFQNT
                     WAEGLLGFTSTGSIGSRVPLLLFVILFGLSMDYQVFVISRIREAALAGVPTRRAVLDGV
                     GGSARVVTSAAFVMVTVFASFVPLHIIEMKQMGFSLAVAVLLDAAIIRIMILPATMLLL
                     GERSWWPSRGMRRAGAAAVRPTEKVG"
     gene            16413..17624
                     /locus_tag="K2F47_RS08070"
     CDS             16413..17624
                     /GO_function="GO:0000155 - phosphorelay sensor kinase
                     activity [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1048: sensor
                     histidine kinase"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: protein motif:HMM:NF014567.5"
                     /locus_tag="K2F47_RS08070"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="sensor histidine kinase"
                     /protein_id="WP_242902127.1"
                     /transl_table=11
                     /translation="MDAWPQHDDRRQARNLVRWYAALWVVGGLCPQVIAAIDDHGGVRV
                     WGIVLPVALGACYAVTAPLPRVLPPPVFLCLLAAGIGAESYVRAGAASLYIASLPHFWI
                     LAGNPRRAAALSGAAGVLTLVGEAARGGDVPSGNMLFTVSGFVAGLLLGLAAYRYVRQT
                     EERARRLAADLAVAQRELAEANRRQGAAEERERLAREIHDTLAQGFASIIVLAEAARAG
                     LGAEPGRSEQQLRSIERTARDNFAEARALVDSARRDGPAQGPVAATLRRVLDRFTEDTG
                     IPVGAELPDVECDQPARIALLRCTQESLANIRKHADASSVGVVLERYPHGVELEITDDG
                     RGFVVGASSGFGLEGMRRRLAELGGELTVTSSVGDGTRILAMIPTSPVDPTSTQTPDDP
                     AGVR"
     gene            17621..18262
                     /locus_tag="K2F47_RS08075"
     CDS             17621..18262
                     /GO_process="GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1016: LuxR family
                     DNA-binding response regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020544254.1"
                     /locus_tag="K2F47_RS08075"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="response regulator transcription factor"
                     /protein_id="WP_242902128.1"
                     /transl_table=11
                     /translation="MTDRTLRVIVVDDHTVMRAGVVALLATEPGIEIVGEAGDGRAAVE
                     LAERLRPDVALVDLRMPVLDGASATAEIVAGGSGTRVLILTTYDTDAEIERAIEVGAVG
                     YLLKDTTRERLADAIRSAARGETVLAPRVAERLVARMRRPAPVPLTAREVDVLNGVADG
                     LSNADIGRRLVIAEATVKTHLLRVFAKLDVSDRTHAVVVAMERGLLPRPR"
     misc_feature    complement(18309..18323)
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence: weak,
                     score: 15.01"
                     /tool="antismash"
     gene            18375..18872
                     /locus_tag="K2F47_RS08080"
     CDS             18375..18872
                     /EC_number="2.3.-.-"
                     /GO_function="GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA]"
                     /GO_function="GO:0016746 - acyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012853173.1"
                     /locus_tag="K2F47_RS08080"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="WP_242902129.1"
                     /transl_table=11
                     /translation="MEYEVRLARPSDLPGLPAIEISADRLFAPLGIVFPPGPTVIEQMA
                     GADAEILVAGDPPVAFAAVEDVDGAPHLEQIAVRGDLVGRGIGTRLLRAVRERAAAAGA
                     PGVSLLTFRDVPWNGPWYARQGFAELPEQRWGPGLRAYWKAEIEAGLHDLGPRLMMWAP
                     SG"
     misc_feature    complement(18940..18956)
                     /note="TFBS match to HexR, Glucose-responsive regulator,
                     confidence: weak, score: 21.52"
                     /tool="antismash"
     misc_feature    complement(18943..18952)
                     /note="TFBS match to ToxT, Regulator of MSHA biosynthesis,
                     confidence: weak, score: 14.35"
                     /tool="antismash"
     gene            19048..20064
                     /locus_tag="K2F47_RS08085"
     CDS             19048..20064
                     /EC_number="3.1.-.-"
                     /GO_function="GO:0016788 - hydrolase activity, acting on
                     ester bonds [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019630638.1"
                     /locus_tag="K2F47_RS08085"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="SGNH/GDSL hydrolase family protein"
                     /protein_id="WP_242902130.1"
                     /transl_table=11
                     /translation="MRGRFGERGLALTALVGLLALAVVPLVALPAVRCEVFGAGCHRPP
                     QEVRADPVSAPGRQLTPVQAATRGGYVALGDSYSSGVGAEATIGDNNPLERCHRTSKAY
                     YNEVSKAFPFAKGTSFWACSGATTADVRNGRHGEPSQLGRLNADTSLVTLSVGGNDIGF
                     SRVVAGCVVKLPWSRSCFRQGDDIAKKMSDLRRNLPELIGQIHARAPRARIILMGYPKA
                     FSEVDGTGGDNLRVSEQQWLNARAYDLGQLIRASAAEADRRIAARHQQGSVEFVDSYSA
                     FAGHEVGSRQPYMNGLTVNLSALEAEPRSYHPTVSGQHALAGLFIEQVKKGPGRPVS"
     gene            complement(20159..21223)
                     /locus_tag="K2F47_RS08090"
     CDS             complement(20159..21223)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1287: AraC family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017588025.1"
                     /locus_tag="K2F47_RS08090"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="WP_308198380.1"
                     /transl_table=11
                     /translation="MRDPPLLDWHDHPDASGTPASVRSDVVRYVLAMHVVAVLALDGVV
                     AFDLAVPGQVFGTSTTDRDVPLYETRVCGLPGGAATSATGGRMRVEPPFGLDALATADT
                     IVVPGHDQPYDHPAEHPPEVLDALRDAAERGTRIASICVGAFVLAAAGLLDGRRATTHW
                     MYAHRLARLHPRVEVDASVLYVDDGQVLTSAGVAAGIDLCLHVVRRDHGAATAARTARR
                     IIMPPQRDGGQAQFIRHEDPPDGDTALQPTLAWLEANLNRPLTLDDIARHASVSVRTLT
                     RRFREQAGTTPQRWLSRARVHRAQQLLESTDLPVERVAAESGFGSPVTLRAHFARRVGA
                     SPQSYRAAFRARAS"
     cand_cluster    21056..31451
                     /candidate_cluster_number="3"
                     /contig_edge="False"
                     /detection_rules="ectoine_synt"
                     /kind="single"
                     /product="ectoine"
                     /protoclusters="2"
                     /tool="antismash"
     protocluster    21056..31451
                     /aStool="rule-based-clusters"
                     /category="other"
                     /contig_edge="False"
                     /core_location="[26055:26451](-)"
                     /cutoff="20000"
                     /detection_rule="ectoine_synt"
                     /neighbourhood="5000"
                     /product="ectoine"
                     /protocluster_number="2"
                     /tool="antismash"
     proto_core      complement(26056..26451)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="ectoine_synt"
                     /neighbourhood="5000"
                     /product="ectoine"
                     /protocluster_number="2"
     gene            21222..21884
                     /locus_tag="K2F47_RS08095"
     CDS             21222..21884
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017601624.1"
                     /locus_tag="K2F47_RS08095"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="HD domain-containing protein"
                     /protein_id="WP_242902131.1"
                     /transl_table=11
                     /translation="MTDTADRFAEFAMPDTDLTRAVHDLAFAAELRALAHHSVRVYLFG
                     RALGEARGLRPGDAYDDELLFVACLLHDMGLTEQGDGDQRFEVDGADLAAGFLEGYGVA
                     PDRIRVVWEAIALHTSVGIPPRMRPEIALTSAGAGADIAGLQADRLPDGYADRVHAAYP
                     RLEPGGGLTHLVVDQIVRNPRKAPLGTLPYEIARQLGADIPLPSWTEQVGGAWRGVA"
     gene            complement(21978..22799)
                     /gene="ehuA"
                     /locus_tag="K2F47_RS08100"
     CDS             complement(21978..22799)
                     /GO_component="GO:0009898 - cytoplasmic side of plasma
                     membrane [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0033286 - ATPase-coupled ectoine
                     transmembrane transporter activity [Evidence IEA]"
                     /GO_function="GO:0033288 - ATPase-coupled hydroxyectoine
                     transmembrane transporter activity [Evidence IEA]"
                     /GO_process="GO:0033308 - hydroxyectoine transmembrane
                     transport [Evidence IEA]"
                     /GO_process="GO:0051470 - ectoine transmembrane transport
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="ehuA"
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018657168.1"
                     /locus_tag="K2F47_RS08100"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="ectoine/hydroxyectoine ABC transporter
                     ATP-binding protein EhuA"
                     /protein_id="WP_242902132.1"
                     /transl_table=11
                     /translation="MPPTDTTPEKDAAPVRGDAPGIRFEKVVKRFGSNTVLRELDFTVA
                     PGERVTLIGPSGSGKTTILRLLMTLEKPDGGLIFVGDDPLWHMDRGGKRVPANQKHLHE
                     MRKRIGMVFQQFNLFPNMNVLRNLTEGPMRVLGVPKDAAVERARGLLDLVGLADKIDAH
                     PSQLSGGQQQRVAIARALAMEPQVLLLDEVTSALDPELVVGVQDLLRDIARQSDLTLLC
                     VTHEMTFAKDISDRVLMFDEGQIVEEGPPEQMFGEPSEQRTRDFLQAVLAT"
     gene            complement(22786..23439)
                     /gene="ehuD"
                     /locus_tag="K2F47_RS08105"
     CDS             complement(22786..23439)
                     /GO_component="GO:0005886 - plasma membrane [Evidence IEA]"
                     /GO_function="GO:0033286 - ATPase-coupled ectoine
                     transmembrane transporter activity [Evidence IEA]"
                     /GO_function="GO:0033288 - ATPase-coupled hydroxyectoine
                     transmembrane transporter activity [Evidence IEA]"
                     /GO_process="GO:0033308 - hydroxyectoine transmembrane
                     transport [Evidence IEA]"
                     /GO_process="GO:0051470 - ectoine transmembrane transport
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="ehuD"
                     /gene_functions="transport (smcogs) SMCOG1096: polar amino
                     acid ABC transporter, inner membrane"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019630633.1"
                     /locus_tag="K2F47_RS08105"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="ectoine/hydroxyectoine ABC transporter permease
                     subunit EhuD"
                     /protein_id="WP_242902133.1"
                     /transl_table=11
                     /translation="MEWDWSYTGDIIPDLLRGLRYTLIATLLGYLIAVVLGLVWTMLRR
                     TPNVIVRQVVRWVTEFIRCTPLIPQLFFAFYVLPTWGLTFGKLTVGVLMLGIHYSTYMA
                     EVYRAGIADVPRGQWEAAKALNLPQTRVWLDVVLPQAFRKVIPTLGNYLIAMFKDSPLL
                     LAIGVPELLTSARSVGARTFEYLEPMTMVGVLFILVSVISSILLRRLERHYATN"
     gene            complement(23439..24158)
                     /gene="ehuC"
                     /locus_tag="K2F47_RS08110"
     CDS             complement(23439..24158)
                     /GO_component="GO:0005886 - plasma membrane [Evidence IEA]"
                     /GO_function="GO:0033286 - ATPase-coupled ectoine
                     transmembrane transporter activity [Evidence IEA]"
                     /GO_function="GO:0033288 - ATPase-coupled hydroxyectoine
                     transmembrane transporter activity [Evidence IEA]"
                     /GO_process="GO:0033308 - hydroxyectoine transmembrane
                     transport [Evidence IEA]"
                     /GO_process="GO:0051470 - ectoine transmembrane transport
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="ehuC"
                     /gene_functions="transport (smcogs) SMCOG1096: polar amino
                     acid ABC transporter, inner membrane"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017621333.1"
                     /locus_tag="K2F47_RS08110"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="ectoine/hydroxyectoine ABC transporter permease
                     subunit EhuC"
                     /protein_id="WP_242902134.1"
                     /transl_table=11
                     /translation="MSEVLDGYEQWLKGAWLTLQLTVYGSGVALVLALVFGLAGTSRHA
                     WIRVLNRVYVEFFRGTATLVLLFWFFYALPLVGIRLNSTMVAAVLALGLNIGAYGAEVV
                     RGSIKAVPRAQYEATVALNFTPLQRMRRVLLPQGFALMLPPFGNLLIELMKGTAIVSLV
                     GLTDLTTVSKNLQSSTGETVASFSLVLVLYFVVAQILQLFVRFAERRVDRMLGRRPSRE
                     PALGTVAAGAPGAGVAR"
     gene            complement(24163..25056)
                     /gene="ehuB"
                     /locus_tag="K2F47_RS08115"
     CDS             complement(24163..25056)
                     /GO_component="GO:0030288 - outer membrane-bounded
                     periplasmic space [Evidence IEA]"
                     /GO_function="GO:0033286 - ATPase-coupled ectoine
                     transmembrane transporter activity [Evidence IEA]"
                     /GO_function="GO:0033288 - ATPase-coupled hydroxyectoine
                     transmembrane transporter activity [Evidence IEA]"
                     /GO_function="GO:0033294 - ectoine binding [Evidence IEA]"
                     /GO_function="GO:0033295 - hydroxyectoine binding [Evidence
                     IEA]"
                     /GO_process="GO:0033308 - hydroxyectoine transmembrane
                     transport [Evidence IEA]"
                     /GO_process="GO:0051470 - ectoine transmembrane transport
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="ehuB"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1091: glutamine-binding lipoprotein glnH"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019630631.1"
                     /locus_tag="K2F47_RS08115"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="ectoine/hydroxyectoine ABC transporter
                     substrate-binding protein EhuB"
                     /protein_id="WP_242902135.1"
                     /transl_table=11
                     /translation="MTSSRRDFLRTAVLLSAAAPLAAAGCSTTDPKEEKSGGGSLQKAK
                     DAGKITVGFANEAPYGYTDKSGKLTGEAPELARVIFKELGIDKVTGVQVDFSGLIAGLN
                     AKRFDVVAAGMFITPERCNSVAFSDPEYVAKSAFMVRKGNPKGLLKQDDPGKKGVKVGV
                     LEGAVEQGYAEKSGVKKGNIQVFADQASGFEGLKAGRVDCIWLTRISLANLLTKHEGEP
                     YEVTAPFTPVIDGKEQFGAGAFAFRKADNDLLTAFNGKLAELKQGNRLLPILQPFGFTQ
                     AEIPTAADTAAKFCKG"
     misc_feature    complement(25094..25108)
                     /note="TFBS match to OsdR, Development and stress
                     management regulator, confidence: weak, score: 24.27"
                     /tool="antismash"
     misc_feature    25140..25153
                     /note="TFBS match to PerR, Peroxide regulator, confidence:
                     weak, score: 15.02"
                     /tool="antismash"
     gene            complement(25151..26056)
                     /gene="thpD"
                     /locus_tag="K2F47_RS08120"
     CDS             complement(25151..26056)
                     /EC_number="1.14.11.55"
                     /GO_function="GO:0016706 - 2-oxoglutarate-dependent
                     dioxygenase activity [Evidence IEA]"
                     /codon_start=1
                     /gene="thpD"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PhyH"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019630630.1"
                     /locus_tag="K2F47_RS08120"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="ectoine hydroxylase"
                     /protein_id="WP_242902136.1"
                     /sec_met_domain="PhyH (E-value: 3.5e-36, bitscore: 122.3,
                     seeds: 39, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSIIESHPTIDDAYPTRKAAEAALLYRQDPVVYGAPQDGPVDAAT
                     LDSFDANGYLTVEELLTPAEVEDYRAELRRMAADPAILADERTVTERGSDEVRSIFEVH
                     RISEVFAQLVRDPRVVGRARQILGSDVYVHQSRVNYKPGFTGKDFYWHSDFETWHAEDG
                     MPRMRAVSISIALTENFVHNGGLMIMPGSHKTFVACVGETPSDHYKESLRGQEIGTPDP
                     GSLSILADKHGIELFTGPAGSATMFDCNCMHGSNGNITPFPRSNVFIVFNSVENTCVEP
                     FAAPAPRPSFIGARDFTPVA"
     gene            complement(26056..26451)
                     /locus_tag="K2F47_RS08125"
     CDS             complement(26056..26451)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     ectoine: ectoine_synt"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017567884.1"
                     /locus_tag="K2F47_RS08125"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="ectoine synthase"
                     /protein_id="WP_242902137.1"
                     /sec_met_domain="ectoine_synt (E-value: 8.2e-52, bitscore:
                     171.3, seeds: 10, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIVRSLEEIIDTERDVRAETWCSRRFVLAKEGVGFSLHETILYAG
                     TETRMWYANHIEAVYCIGGQGELINEETGEKHRIEPGVMYLLDGHEHHTLRAHTDVRTV
                     CVFNPPCTGREVHDENGIYPLLTEEDA"
     misc_feature    26443..26458
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: weak, score: 18.49"
                     /tool="antismash"
     misc_feature    complement(26446..26461)
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: weak, score: 17.24"
                     /tool="antismash"
     gene            complement(26519..27781)
                     /gene="ectB"
                     /locus_tag="K2F47_RS08130"
     CDS             complement(26519..27781)
                     /EC_number="2.6.1.76"
                     /GO_function="GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA]"
                     /GO_function="GO:0047307 - diaminobutyrate-pyruvate
                     transaminase activity [Evidence IEA]"
                     /GO_process="GO:0019491 - ectoine biosynthetic process
                     [Evidence IEA]"
                     /NRPS_PKS="Domain: Aminotran_3 (21-357). E-value: 1.4e-74.
                     Score: 243.0. Matches aSDomain:
                     nrpspksdomains_K2F47_RS08130_Aminotran_3.1"
                     /codon_start=1
                     /gene="ectB"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Aminotran_3"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1013: aminotransferase class-III"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018657162.1"
                     /locus_tag="K2F47_RS08130"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="diaminobutyrate--2-oxoglutarate transaminase"
                     /protein_id="WP_242902138.1"
                     /sec_met_domain="Aminotran_3 (E-value: 1.4e-74, bitscore:
                     248.0, seeds: 13, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDVFARMESEVRGYCRGWPTVFTTAKGSHMTDENGRTYLDFFAGA
                     GTLNYGHNNPELKRRLIDYLAGDAVVHGLDMYTTAKRDFLERFNEYVLTPRGLDYKVQF
                     PGPAGNHAVEAALKLARKYTGRETIVSFTNAFHGMTLGALAVTGNSMKRTGAGVPLGHG
                     VAMPYDNYLDGRTPDFLLFETMLDDSGSGLDKPAAVIVETIQGEGGINVATAEWLRGLQ
                     DLCRRHDILLIVDDVQMGCGRSGPFFSFEDAGITPDIVCLSKSLSGYGLPFAVTLMRRD
                     LDVWEPGEHNGTFRGFNPAFVTAVAALEEYWVGAGLEKQTLAKGQQVETALNAIALQHA
                     GAVDSVRGRGLAWGLVMSDAELAPKVCEEAFRRGLLMETSGPESEVVKLLPPLTTSEAD
                     LGQGLEILAESVEAVRSTVAV"
     aSDomain        complement(26711..27718)
                     /aSDomain="Aminotran_3"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_K2F47_RS08130_Aminotran_3.1"
                     /evalue="1.40E-74"
                     /label="K2F47_RS08130_Aminotran_3.1"
                     /locus_tag="K2F47_RS08130"
                     /protein_end="357"
                     /protein_start="21"
                     /score="243.0"
                     /tool="antismash"
                     /translation="FTTAKGSHMTDENGRTYLDFFAGAGTLNYGHNNPELKRRLIDYLA
                     GDAVVHGLDMYTTAKRDFLERFNEYVLTPRGLDYKVQFPGPAGNHAVEAALKLARKYTG
                     RETIVSFTNAFHGMTLGALAVTGNSMKRTGAGVPLGHGVAMPYDNYLDGRTPDFLLFET
                     MLDDSGSGLDKPAAVIVETIQGEGGINVATAEWLRGLQDLCRRHDILLIVDDVQMGCGR
                     SGPFFSFEDAGITPDIVCLSKSLSGYGLPFAVTLMRRDLDVWEPGEHNGTFRGFNPAFV
                     TAVAALEEYWVGAGLEKQTLAKGQQVETALNAIALQHAGAVDSVRGRGLAWGLVM"
     gene            complement(28045..28593)
                     /gene="ectA"
                     /locus_tag="K2F47_RS08135"
     CDS             complement(28045..28593)
                     /EC_number="2.3.1.178"
                     /GO_function="GO:0033816 - diaminobutyrate
                     acetyltransferase activity [Evidence IEA]"
                     /GO_process="GO:0019491 - ectoine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="ectA"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018657161.1"
                     /locus_tag="K2F47_RS08135"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="diaminobutyrate acetyltransferase"
                     /protein_id="WP_242902139.1"
                     /transl_table=11
                     /translation="MAAQPLESPTRRPERTETNADVQLQEPSLTDGPGLWRIARESHVL
                     DVNSPYSYTLWCRDFADTSVVARDGAALCGFITGYVRPARPDTFFVWQVAVDKSYRGRG
                     LARRMLDRLARRQAACGHRYLEATVTPGNEASTAMFSSFARDHGCDLDRSPLFGTEHFP
                     GRGHEPEVLFRIGPIPGAN"
     misc_feature    28661..28677
                     /note="TFBS match to RicR, Copper-responsive regulator,
                     confidence: weak, score: 22.56"
                     /tool="antismash"
     misc_feature    complement(28662..28677)
                     /note="TFBS match to CsoR, Copper-responsive repressor,
                     confidence: weak, score: 21.54"
                     /tool="antismash"
     misc_feature    complement(28692..28706)
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence: weak,
                     score: 14.65"
                     /tool="antismash"
     misc_feature    28857..28872
                     /note="TFBS match to CRP, Cyclic AMP receptor protein,
                     confidence: medium, score: 17.4"
                     /tool="antismash"
     misc_feature    complement(28875..28889)
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence: weak,
                     score: 14.83"
                     /tool="antismash"
     gene            complement(29223..30191)
                     /gene="pip"
                     /locus_tag="K2F47_RS08140"
     CDS             complement(29223..30191)
                     /EC_number="3.4.11.5"
                     /GO_component="GO:0005737 - cytoplasm [Evidence IEA]"
                     /GO_function="GO:0004177 - aminopeptidase activity
                     [Evidence IEA]"
                     /GO_process="GO:0030163 - protein catabolic process
                     [Evidence IEA]"
                     /NRPS_PKS="Domain: Abhydrolase_1 (39-301). E-value:
                     8.5e-37. Score: 119.0. Matches aSDomain:
                     nrpspksdomains_K2F47_RS08140_Abhydrolase_1.1"
                     /codon_start=1
                     /gene="pip"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Abhydrolase_6"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF00561"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1036: alpha/beta hydrolase fold protein"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012853167.1"
                     /locus_tag="K2F47_RS08140"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="prolyl aminopeptidase"
                     /protein_id="WP_242902140.1"
                     /sec_met_domain="Abhydrolase_6 (E-value: 4.1e-10, bitscore:
                     37.5, seeds: 455, tool: rule-based-clusters)"
                     /sec_met_domain="PF00561 (E-value: 7.6e-33, bitscore:
                     111.1, seeds: 48, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MELRTLYPPIEPYDSGLLDVGDGDSVYWEVCGNPEGKPAVMVHGG
                     PGGGCSAAHRGQFDPEAYRIVLFDQRNCGRSVPHAKDPGVSLEANTTWNLVADMERLRE
                     HLGIERWLVFGGSWGSALSLAYAQTHPERVSELVLRGIFTLRPFELYWFYQEGASLLFP
                     DLWERYVEPIPEDERDDLIAAFHTRLNSPDRAVRVAAAQAWSTWEGSTVTLRPDPALAE
                     TFAEPDYAVAFARIENHYFVNEGFFEPDQLIRDVDRIRHIPAVIVQGRYDVCTPAATAW
                     DLHRAWPEADFHIVDDAGHAYSEPGILHRLIEATDRFANAR"
     aSDomain        complement(29289..30074)
                     /aSDomain="Abhydrolase_1"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_K2F47_RS08140_Abhydrolase_1.1"
                     /evalue="8.50E-37"
                     /label="K2F47_RS08140_Abhydrolase_1.1"
                     /locus_tag="K2F47_RS08140"
                     /protein_end="301"
                     /protein_start="39"
                     /score="119.0"
                     /tool="antismash"
                     /translation="VMVHGGPGGGCSAAHRGQFDPEAYRIVLFDQRNCGRSVPHAKDPG
                     VSLEANTTWNLVADMERLREHLGIERWLVFGGSWGSALSLAYAQTHPERVSELVLRGIF
                     TLRPFELYWFYQEGASLLFPDLWERYVEPIPEDERDDLIAAFHTRLNSPDRAVRVAAAQ
                     AWSTWEGSTVTLRPDPALAETFAEPDYAVAFARIENHYFVNEGFFEPDQLIRDVDRIRH
                     IPAVIVQGRYDVCTPAATAWDLHRAWPEADFHIVDDAGHA"
     misc_feature    complement(30687..30701)
                     /note="TFBS match to VqsM, Regulator of quorum-sensing
                     signalling systems, confidence: medium, score: 18.92"
                     /tool="antismash"
ORIGIN
        1 ggatgcgccg catcagcagg tcgcgcgcgt cgtcggggtc gtcgacgccg acgaggtcca
       61 cataggtgat cgtcgacagc aggccgtcga tcgggcagtc ctcgatgcgg accgtgacga
      121 gcttgcgcgc cgggtcgtcg gggtcggcgc gcagcgccgc catccactcc agccgcccgt
      181 accgggaccg caggtagttg cgcgacagca ccgcgacgac ggccttcgcc tccgacaggc
      241 cccggtccat gaagtcgatg aagttcgtgc cgggcacgaa gtcccacgcc tgcatcatcg
      301 tccggtgccc ggccgcttcg agctgccagg cgatccagga cgcccaccgc tcgtccgcgg
      361 gcgagtagct gatgaagaag tcggtcggac gctcctgcct ggagtggtca ccggggggtg
      421 tcatgccgcc agtatcgcgt gccgggacgg ggagttcagc aactcgtccc gcctgtggaa
      481 aaccgcgccg cacacccggc gggacgccgc gccgcgccgc ctatgggatc atgtcgcgcg
      541 tgccgtcccc gcccgccgcc ctgcgccgag ccgtccggtc cgtgggggtc ctggaccgcg
      601 tcagggcggg gctgctcgcg ctcggcctgc tcttcgtcgc gacgggcctg ctcccgcccg
      661 cgacggcgcg cgacagcgtc gagcgcatcg cgcccctcct gctgttcctg ctcagcgtca
      721 tcgtgttggc ggagctgacc aaggaggcgg gggtcttcga cgcgatcgcg cagcggatgg
      781 cgcgcgcggg acgcggcaac tacgtcgcgc tgttcctgct gtgcgtgggg ttcgcgtcgg
      841 tcaacaccgt cttcctgaac ctcgacacga ccgcggtgct gctgacgccg gtcatgctgg
      901 cgctcgcggc gcgcgcgcgg atcgccgcgc tgccgctcgc catgacgacg gtgtggctgg
      961 ccaacaccgc gagcctgctg ctcccggtgt ccaacctgac caacctcctc gccgccgacc
     1021 gggtggccct ggagaccccg gcgttcgcgg cccggatgtg gctgccgcag gtcgccgtcc
     1081 tcgccgtcac gatgctgctg ctgtgggtgt tcttctggcg gcgcggcatg cgcggcgccg
     1141 actcctacga cccaccggac gtcgcgcccg tccgcgaccg ggtcctgttc tccgcgacgg
     1201 gtgtcgcgtg cctgctgttc atcggcgcga tcctcgcggg cgtccacacc ggcctccagc
     1261 tcggcctcgc cgcgaccgtc gccgccgtgg tggccgtggc cgcgttcgcc gtccgcgacc
     1321 ggtcggcgct gcgcggcgag ctgatcccgt ggcggctgat ggtgttcgtg accggcctgt
     1381 tcctggtcgt ccccaccttg gagcggtacg gcctggacga ggtgatgcgc tccctggtcg
     1441 gcggcgacga cggtgtcgcg ggcgcggcgc gggcggcgtt cgcgggggcg gggctgtcca
     1501 acgtcctgaa caacctgccc gcctatgtcg cgggggagtc cgcggtcccc gagtccaacc
     1561 gggaccagct gctgtccctg ctcatcggca cgaacgtggg cccggtcatc acgccgtggg
     1621 ggtcgctggc gacgctgctg tggttcgagt ggtgccgccg ctgggacgtg cgcgtgccga
     1681 tgcgcaagtt cgtcatcaca gggacggtcc tggccgtgct gggctgtgcc gccgccgtcg
     1741 cggcgctgct ggtgacccgc tgaactcggg acgagcgccg actaccggac gagcgggatc
     1801 tggccgtccg gcccggcgac gtccagcgcg cggttcgcgg tctccacaag ccgcgcgagc
     1861 agctccgggc gggccgcgac gaaccccagc tccgacggcg ggcggtcgat gctcagctcg
     1921 taggggccgc cgtccaggcg gcgcagctcc gcgcccgcct cggccgccag cagcgcgccc
     1981 ggcggcaggt cgacgagctc gggctggtag ccgacgatcc cgtcgatgtc gccgcgcgcc
     2041 agcatcgccc acgcgaccag cggcgcccac agttgcagga gccgcgagca gcgcagctcc
     2101 agcgccgagc gcagcgcgaa cgccgacggg tcgcccgcct tgaccgcgtg cccctgcgtc
     2161 cagcccagca cagggttgcg ctcccggccg gggcggggac gcggcgccag cgacagcggg
     2221 gcgccgtcgg ggtcgagggc cccctcgccg cgcaccgccg tccacgtccg ccccgagacg
     2281 gggtcgtgga cgacgcccag cacggggatg gtccccgcgc acagcgccag ccccaccgcg
     2341 tacacgggca tgccgatcgc gacgttgttg gtgccgtcga gcgggtcgac cagccagacg
     2401 aggtgggcgc cgtccgcgcc gtcgagcacc cccgactcct cggcgatgat ccggtgcccg
     2461 gggtaggcgg tgcgcagccg tccgacgatc agctcctcgg cggcggtgtc cagttcggtg
     2521 acgacgtcgc cgttccggcc cttggggcgg gcgaccagcg ggccgcccgt gccggcgcgc
     2581 accagcgcgc cggccgcctc ggccgcctcg accgccaccc ggcgggcctc gcagagatcg
     2641 accggtaggg ccggtgacgg gggcgtggat ctcatcgctg cctctccagt cgggtccggg
     2701 gctcgggggt ccggtggctc gggggccggt ggccgcctac cggcgggtcg gtgacaggcc
     2761 gccgagggag cagccttccc cgggcggggc ggggtgggcg ttcgcgaccg cgcgcgccga
     2821 ccggtggagc gcgcgcgccg cctcgtccgg ttcggaccgc gcgcggcgca cctggtgggt
     2881 cgcgacgtcc agcgggccga gcgacaggtc gccgctcccg ggcgtctggc ggccgagcgc
     2941 gaccgtggcc gcgtcccgcc cgtcctcgat cagcgtgctg tggaacacgc ccgcgggcag
     3001 agtgtacgac tcgcccgtcc cgtgggcggt ggaacgaccg ggagagtatc ggacggtgcg
     3061 tccggtggcc ctcagctcgt cgacctcgcc ccggctgacg acctcgaaga cctgcgccgc
     3121 cgccccgccg gagcccccgc cgacgtccat ccggacgttg cggaccgtcc cgtacaggac
     3181 gaagctcagc aggtcccagc tgtggcagtg cacgggggag gtggtggagg gcgcggaatc
     3241 cacctcggac gtccagatgt gcaggcacac gccgaagtcg ccgctgcgct ccacgggaag
     3301 gcacaggaac ccgaggggat gccttacggc cgggacgcgg gaccgccccg ccgcgacgtc
     3361 cgcgagcaca cggcccgccc atgccgggag cgtccgcgcc gccgttccgg cctcgatctc
     3421 cctgcggatc tcctcgtacc tcatcgctcg cacccgatgt cgctgttgcg ttgtggcgtc
     3481 cgcgtacggc aggcccgcgc ggacgcggtc actcgtaggg gtccttgggc cgcagcgcct
     3541 tccggatgat ctcgatgacg tcccggtcgg tgtagccctg ggccatgtcg atgccgatca
     3601 cctcgtagag cctgcggacc tgctcgacgg tcggctcgtc gtccagcggc gcgagccgcg
     3661 cgtgctccac cgggacgcgg cgcgcctggt cgaggctcgt cagcagctcg gcgctgagcc
     3721 agctgtagta gaacttcgtg ctgtccacga ccagcgcctg gccgcgcgga ttgtcgcggg
     3781 tgaccacgat cagcgaggac gacaggtcgt agcgcagcgt cgtcatcgtc cgcgccaggc
     3841 cgatgtcgat gtcgagcatc ccgaaccgct gcttgtgcca gcacgcggcg aggatcgtgg
     3901 cgtaggcctc cttgcgggtg cgctccagcg tccacggctc gccggtgccg tcgggcccgt
     3961 cggccgacga gcggcggtgc cgggcgtagg cctcgcagac ctccacgtcc gtcgggtcga
     4021 tgatctccag ccggaacagc agcgtccggc cgtcccggcg ggcggcggcg acggtctcgg
     4081 gcagcgtctt ggcgcggatg taggtgccgg tgccgccctt gaagatccag cggtcggtgt
     4141 cgcggcgcgc ctcctccagc acctgcgcca cctgcgcgcc gctgatcacc cggacgatcg
     4201 tggtctcgtc cagcgcgcgc ttggtgtcgg ccaggacccc ctcgaacgcc tcgatgtggc
     4261 tcagcctgcc gctcagctcg tccagcgtgg tcgaggacgc ccgcagcgtg tcgcgcacct
     4321 ccgcctcgac cgggacgcgc cgcccccggt cgcgcagcac cgacgtcgcc aggaggccga
     4381 ccaccgcgag gatcgcgctg ttggtgatct cgtcctcgtg ggggaggtcc accccgaccc
     4441 cgagcaccgc gaccgtgatg gccagcacca gcgcgatgaa ggcgtcggcg ttcttcccga
     4501 gccaggtggc gaagcgggtc attgtatgcg ttttccccgt ccttgtcggc gccgtcatcg
     4561 taaccacagc accgcgaggg cggccacagg cccgcgtccc ctgtgcggcc ggggctgagg
     4621 cgccgcaggt cacgttcctc tcaggcgggg gaggccatgc tttccggcat ggacgacctt
     4681 ggtcccctcc gccccctaca ctcatcgcat gcagctgcgg ggctggtggt cggcgggatg
     4741 gccgacaccg cgttcacggg cgctggacct caccctcgcg gtgtcgctgg cggtcgtgga
     4801 cggcgtgttc ctgtggttcg ccccccagga cttctggctg ccgccgcccg tgacgtcggc
     4861 cggcagcttc ctcctcggcc tgggcctggt cttccgcagg cggcaccccg tccggctcgc
     4921 gctcctcgcg gtcgcgctcg gcacggtcgc gggcgcgggc gtgttcgcgc tggtggtgat
     4981 cctctattcg ctggccgcct acacccccaa ccgccggacg gtctggacga tcgccgccgt
     5041 cgggtacgtc tccgggatcg ccttccccgg ccccaccgag aacgacgacc cgttcctcgc
     5101 ccaggcgatc ttcggggtgg cgttcacggc cgtccccatc ctcctgggtc tctacatggg
     5161 ggcgcgcaag cagcttctgg cttcgctaca ggaacgtgcc gcccggctgg aacgcgagca
     5221 gcacctcctc gcggagcgcg cgcgggggga ggagcgcacc cgcatcgccc gcgagatgca
     5281 cgacgtcgtc gccaaccgga tcagtgtgat ggtcgtccac gcgggcgccc tgaaggcgat
     5341 cgccgtccgc gacccgggcc gggccgccga gaccgccacc gtcatcggcg acatgggacg
     5401 gcaggcgctg gaggagctcc ggcacgtgat cggcgtcctg cgccagggcg aggaggcgct
     5461 gccccaggag gcggtgacgc tcgcccatgt ccgcgagctg gtcgaccagt cgggcgccgc
     5521 gggcctggtg gtcgacctgg ccgtgcgcgg cgaggagcag ccgatgccgc ccgccgtcgg
     5581 gcggaccgtc taccggctcg tccaggaggc gctgaccaac gtccacaagc acgcgggcgc
     5641 cgccgacacc cgcgtcgacc tcggcctgct gcccgaggcc gtcgaggtcg agatcgccaa
     5701 cgacgcgccc accgccccgc ccgaccacgg gctgccgagc ggcgggcacg gcctggtcgg
     5761 gctgcgcgag cgggtcaccg cgctcggcgg cagcttcgag gccgggccct gcccggacgg
     5821 cgggtacgcg gtccgggcca ggctgccgct gcccgcgtcc tgatcgtcgt cgcggggctg
     5881 tgacctgcac ggaccggttt gtcggacgcc gtgcgtacag tgggggagta ctcacaggga
     5941 ggggggccgg atgcggccag tcaccgatct tcggcgccgg gtggcgccgt tcgaggtcgt
     6001 cacggagatg acgccgtccg gcgaccagcc gcaggcgatc agcgagctcg ccgcgcggat
     6061 cgggcgcggc gacaaggacg cggtgctgct cggcgccacc ggcaccggca agaccgccac
     6121 gatcgcgtgg ctggtggaga agctccagcg gcccgtcctc gtgatgcagc cgaacaagac
     6181 gctcgcggcc cagttcgcga acgagctgcg cgagatgatg cccggcaacg ccgtcgagta
     6241 cttcgtctcc tactacgact actaccagcc cgaggcctac atcccgcaga ccgacaccta
     6301 catcgagaag gactcctcga tcaacgacga ggtcgaccgg ctgcgccact cggcgaccaa
     6361 ctcgctgctg acccgccgcg acaccgtcgt cgtcgcgtcc gtgtcgtgca tctacggcct
     6421 cggcaccccg caggagtacg tcgaccggat ggtgcggctc cagaccgggc agcagatcga
     6481 gcgcgacgac ctcctccgcc agctcgtcgg catgcagtac acccgcaacg acctcgcgtt
     6541 cacccgcggc acgttccgcg tccgcggcga caccgtcgag atcatcccgc agtacgagga
     6601 gctcgccgtc cggatcgaga tgttcggcga cgagatcgag aagctcgcca ccctgcaccc
     6661 cctcaccggc gaggtcatca ccgaggacga cgagctgtac gtcttccccg cctcccacta
     6721 cgtcgccggc cccgagcgga tggagcgggc catcgccggc atcgaggccg agctggagga
     6781 gaccctcgcc gtcatggagc ggcagggcaa gctgctggag gcgcagcggc tgcgcatgcg
     6841 caccacctac gacgtcgaga tgatgcggca ggtcggcacc tgctcgggca tcgagaacta
     6901 ctcccgccac atcgacggcc gcgacgccgg gaccgccccc aacaccctcc tggactactt
     6961 ccctgaggac ttcctcctcg tcatcgacga gtcgcaccag accgtcccgc agatcggcgc
     7021 gatgtacgag ggcgacgcgt cccgcaagcg gatgctggtc gagcacgggt tccggctgcc
     7081 ctcggcgatc gacaaccgcc cgctgaagtg ggaggagttc ctggagcgca tcgggcagac
     7141 cgtctacctg tcggcgacgc ccggcaacta cgagatgtcc cgcgtcggcg gcgacgtcgt
     7201 cgagcaggtc atccgcccca ccggcctgat cgaccccgag atcgtcgtca agcccaccaa
     7261 gggccagatc gacgacctca tccacgagat ccggctgcgc accgagaagg acgagcgcgt
     7321 cctggtgacc accctcacca agaagatgtc cgaggacctc accgactacc tcctcgaact
     7381 cggcatccag gtccgctacc tgcacagcga ggtcgacacg ctgcgccgga tcgagctgct
     7441 gcgcgagctg cgcgccggcg agttcgacgt gctggtcggc atcaacctgc tccgcgaggg
     7501 cctcgacctc cccgaggtct ccctcgtcgc gatcctggac gccgacaagg agggcttcct
     7561 gcgctcggag acctccctca tccagacgat cggccgcgcc gcccgcaacg tgtccggcca
     7621 ggtgcacatg tacgccgaca ccgtcacccc gtcgatggag cgcgcgatcg acgagaccaa
     7681 tcggcgccgc gccaagcagc aggcctacaa caccgagcac ggcatcgagc cccgcgcgct
     7741 gcgcaagcgc atcgccgaca tcctcgactc cctcgcccgc gaggacgccg acaccgagac
     7801 cctcatcggc ggcgcgggcc gccagcagag ccgcggcaag gcccccgtcc ccggcctcgc
     7861 ctcccgcacc cgcgaggtcg gccgccacgc cgccgacctc gtcggcgagc gcccccgcga
     7921 ggaactggag ggccttatcg agcagatgac cgcccagatg caccaggccg ccaccgacct
     7981 ccagttcgaa ctggccgccc gcctccgcga cgagatcaag gaactgaagc gcgaactccg
     8041 cgaaatgaag gaggcaggcg tcagctagcc aacgctgtac tcacgaagcc ccgcggcccg
     8101 gggctcccgc ccggcggctg cgctcatgaa gtcccggccg gtttcgtttc aggctcggcg
     8161 ggcgtgttcg cgggtggggg tggtcggggt cgttagccat tgggaggcga ggttgcggta
     8221 gtaggggctg gtgtccagga gctccgcgtg agtgccggac gcgacgatcc tgccctggtc
     8281 gaggacgagg acgctcgccg ccgcgcggac ggtggtgaac cggtgcgcga tgacgagcag
     8341 cgcgcaccgg ccggcggcct cgtcgatcgt gcggtgcagc gccgcctcgc tctccaggtc
     8401 caggtgcgag gtcggctcgt ccagcagcag gagccggggc cgcgcgacga gggcgcgggc
     8461 gatcgccagg cgctgccgct ccccgcccga cagctccctc ccatgctcgc cgacccgggt
     8521 ttcgagcccc ttgggcagcc gcgcgacgag ctcgtccagg ttggtcatgg cgaccgcccc
     8581 gcggatctcc tcctccccgg cctccggagc cgcgtagacc aggttgtcgc ggagggtccc
     8641 gtccaggacc gggcagtcct gctcgacgag cccgatcctc gaccggtggc cgtcgcggct
     8701 cagcgagtcg gcccgcatgc cctcgaccag cacctctccg cggtcggggt cgtagaaccg
     8761 ctcggcgagc gcgaagatcg tcgacttgcc cgcgccggac cgcccgatca gggccacgtg
     8821 cccgcccggc ggcacctgga acgacacccc ccgcagcacc ggccgccccc gcccgtatcc
     8881 gaaccacacc tcccggaact cgagtgccgc cgcccggccg ccgtccgtac tggagtcgcc
     8941 atgagcggaa gcgtgggggg cggcgggtcc gcaggtctcg acgagaggtc gggaggcttc
     9001 ggacggggcg gctgcggcgg cgtcggtctc ttggggcagg gccagggcct cggtgatgcg
     9061 gtggacggcg ccggtgccct gctggacggc gctgaacgcc tcgaagatcg agcccagcgg
     9121 cgccgtcagg tacagcatgt agagcaggaa ggcgaccagg tcggcgacgg agccgctgcc
     9181 gccggcgacg cgcgttccgc cgacgaggag gacgacgagg aacgagccgg tcaccgccag
     9241 ttcggtggcg ggggagacca gcgcgtcgaa cccggccatc cggacgttcg cgacataggc
     9301 ggcctcggcg cggtcgccga tgcgggcgct ctcgcggggt tcggcgcggc cggccttcac
     9361 ggtccggatc gcgctgagcg cgcgttccag gccggcggcc atctcgccgg tcgcctggcg
     9421 gccccgcagc gacgcggccc gcatgccccg cagcgcgagg gcgagcgccg tgcccgcgcc
     9481 cgcgacgatg gcggcgacac agccgaacag cacccagtcc agccacagca tcagcacgat
     9541 cgtcgcggcc aggccgatga cgccggtcac ggcgtcggtg agcccgccgg cgatgatctg
     9601 ccgcagcgcg agcgtgtcgg cgtccgccct ggagatcagg tcgccgatcc ggtgccggtc
     9661 gtagacgggc atgcggagcc gcagcaggtg gtcgatcagg ctcagccgga cgccgaggac
     9721 gatcccctcg ccggtccgcg cgagctggaa gcggaccagg gcctgcacca gcgcctggcc
     9781 gacgaacaga acgaccagcg tgccgaccgc ggtccacggc gtccggcccg acccggcgac
     9841 cgcgatcacg tcccgcgcga ccaggggctg ggccagggcc agcgcggacg ccagcagggt
     9901 cgccgcgacg gtggcggcga tggcgccgcg gtgcccggcg gccagccgca ggacgtcgcg
     9961 cagccccgcc gtgttcgccc ggccgggggc gccctcgtcc tcagcgccca cggtccccgc
    10021 ccccgcgcgg agggacggtg atcagggcgg cgaggtagcc gtccgggacg ttctcctcga
    10081 cgaggcggcc ttcggcctcc acccacgcgt gcgccccaaa cggcggccgg acccggacgc
    10141 cgacgcacca gctcggccac gcgccccaca tccggcacaa caggacggtc gccagcgacc
    10201 ggggcaggca tccccgcggc ccgaggcagg cgaggctgcc ggcgaggacg gcgtcgcgtg
    10261 cccgtttcgc ctggtcgtag gtggcggggg aggcgcccct ggagagcagg gcgaggagcg
    10321 cgcggatgcg cgcgggcggc aggagggcga tcggccgggc caggaggacg gccagccgcg
    10381 cggccgcgcg gcgccgcagc gggcccttcg gggggcgctc cagcgcgctc gggacggtca
    10441 cgaccgcacc agccccgccg tgcgcagctg ccccaccagc gccgtgacgt cccgcagcgc
    10501 ctgtggctcg tcgacgtcga actcctcggc catggtcgcg gcggcctcct cggtggtgct
    10561 gccgtccgcc agcagccgca ggacccgggc ggcggtcgga ttgagctgcc agtagtcgcc
    10621 actgcgctcg tcgaggagca ccgtgccgta ggccgtgtcc gtcgtggaca cgccgggacg
    10681 cagtcgcagg ctcatgcggg gccttccctt ccgtagcggt cttccggacg gctcatcgcc
    10741 gggtcggcgc cccggcgcgg cggtgttcca gggtgcgcag ccagacctcg cagccgaggg
    10801 tggagtacag gaccgcctcg cgcagcgcgg gcgtgtcggg acgggagacg agggccctca
    10861 gccgctcgcc gtccacgagg ccgagccggg ccagccggga gtcgtcgcac agttccagca
    10921 ggtcgcggtt gtgcgcgcgc agcccgtcgg cggcgtccat ggacgcctcc gccttgttgg
    10981 cgcgggcgag gcactcgtcc gggacgatgc cgcgcatggc cgcgacgagg agcggcttgt
    11041 accgccacgg ggtgacccgg tcctcggcgc gcacggcgag gcaggcctcg atcacccggt
    11101 cgtccaggaa gggcgaggcc atcggaaggc ccgcgcgggc gctcgtccac tcccactgcc
    11161 ggatgatgcg cgtgcaggcc cggatggagt gcaggtccat gtgccgcccc cggtcgggcg
    11221 ccagcggctc ggccgtccgg gcggcctcgc gcagcacctg ccgcgccgcc tccgccgcct
    11281 cgggcgtgac ccagtcgaac agccgcggcg ccatgtccca gccgagcgag cccgcgacgg
    11341 tcggccgggc gggggcgcgg aggtcgccgg ccgcgtcgcg gagccaccgg cggtagggac
    11401 ggccgtcggc cagggcacgc gccgccggga cgagcggcca gtcgaacagc gcccggaacc
    11461 cccgcagccg ccgcagcgcg aacagcggcc gcctgcgcag cagcccgtgg tagtgggcct
    11521 cggagcacca ggcgacgtgg tcgccgccga tgccggtcag gtgcaggcgg ctgcccttcg
    11581 ccagcagccg ggggacgtgg tcgagcatcc gggcgcggtc catcacgccg atgctgggct
    11641 cgtccagcgg gtcgtcgatc tccaggagcc cctcgtagac cagcgaggag tcctcggcgg
    11701 gccacaccgc gtgctcgacg ccgggcaggt gcgcggcggc gcgccgcgcc cacgtcaggt
    11761 cctcgtcggc cgggtcgcgg ccgggccagg tggacgcgac gatcccggcc tcgccccggg
    11821 ccgccaggaa gcagaccgag gtcgagtcca gcccgccgga caggtcgcag ctgacgacgc
    11881 cgccgcccgc ggtgcgcgcc tcgaccgccg cggtgagcgc cgcggcgatg tcgtccgcgg
    11941 cggcggcgag cgggcgcacc gcctccggcg cggtccacca gcggcgcacg ctcgcgcggc
    12001 cgtccggctc caccagcagg tgggcacccg gttccacccc ctcgatcccc cgccacaggg
    12061 gcgtgtggag cagcggatgc ggggccggcc acagcaggcg cgcggcgacc tggcgctcgt
    12121 ccagcgcggc cccggtcagc gccgcgagcg tgtcggcgcg gtcggcggcc accgtgacgc
    12181 cgcccgcgcg ggtgtggaag accagccgca gcccggcggc gtccccctgg acgcgcgtcc
    12241 ggccgtccag cgcggcgacg aggtggaagc tccccggcag cgagcggacg agtcggtcga
    12301 gggcggagag gtcgcgcagc cggccggcct cccgggcgag ccgatcgggg ccgatcgggc
    12361 aggtgccgat gatcgcgatc cgggcgtctc ccgccgtggc ctcggtcatc tcggcgtcgc
    12421 tccagcggcc cgccagccag ggccgtccgg acgggtgccg cagcgtgcgt tcggggggcg
    12481 tgggcaggcc cgaggccacg gcgagggccg cctcgtggtc cggtaggacc acgaaggacg
    12541 cctcgccgtg acccggcatg ccatcgtgat caggcatggg ctgcgaacgc ctcgctcagt
    12601 tcttgctgag gatcaggcgg tcgttgccgt ggaactggag caggccggtg tccttgcgga
    12661 aggagccggc cgccacaagg gcgggggtct cgtacttctg cattttctcc tcctcttgcc
    12721 gtgggtttcc cgggagagat ctcccgtgtt ccgccttccg gggttctcgg cggaatgcga
    12781 aacgcgagaa gcatgccatc caggcgagcg ctttgactat cccgccgatt ctcgatcttc
    12841 cggacgcggg agtgatcgat gacggctgcg aggagaaaaa tcgggataag atagccatac
    12901 ctctaggtat ggggcttccg gtaaagccgg ttccctttcc tcggggtcat tgttcggtgg
    12961 cagagatgaa ggatcaagtt aacctgtacg caacctaaga tgatgttgct tggcgcaaat
    13021 gtgcggcata tggcggcgcg cgcccgcggt ccaatcttcg ggcgcggaga agggtgtgcg
    13081 ggatgccgca caccctttgg tctggccttc ggcccgccta tcgtcccgct ctttgtaccg
    13141 gcctttgaga atgccctttg aatcgtcctt tggtgcgtgc gcccgaaggc gggccacacg
    13201 gcttgagggc ggctgcggcc tgagggcgca acggcctgag ggcgggctac ggcttgaggg
    13261 cgaagaacgc ccgcacgcgg gcccggtggt attcgagatc gtcctcgtcg tgctcgacgc
    13321 cgcgcgcgcg ggccagctcg aagtaggcgg tctcgcggcg gatgcggtgg cggatgagct
    13381 gggcgaccgt ctcgtcgtcc atgggcccgg cggtgccgcc cgccgcgtgg tagtcggcga
    13441 cgaagcggcg ccgcagctcg ggggcctcgg cgtgctcgtc cgtccattcg agcgcggcgg
    13501 aggccacctc gaactcgggg gcggcgacga acgcctcgtc ccagtccagg agggcgacca
    13561 ggcggccgcc gcgcgccagc gtgttgccct cgtagtagtc gccgtggacg acctggcgcg
    13621 ccggggtgcg ggcgtggaag tcggcgagcc accggtcgag ccccgggtcg gcgagctcgg
    13681 ggacgtccgc ggggaacgag ccgtccaacc cgatctcggc gaacgaccgg gtgggacgcg
    13741 gcggaggcgc gtagtcggcc agcgcccggt gcagcctggc gaggagcgcg gcggcctggg
    13801 cgcgcgtcgt gggcgcctcg gtgtcgggcc actcgccctc cacatggcgc cacagcgaca
    13861 gcgggcggcc gtcggcacgg acgaccgtgg cgccgtcgcg ggtgcgcagc ggcgccaccg
    13921 cctcgggcat gcgggacgcg gcgtgcgcgg ccaccgcgtg gcaccactcg gtctcggcgt
    13981 cgcttcgcca ggcgggcccg acccgcacca cgagttcgcc gatccggtac gcggccgact
    14041 cctcgccgcc gaacagccgc tcggcggggc cgtcggcggg aaggttccag ccagcctgga
    14101 ccgccttccg catcacgccc gtgagcggcg tctcggcgta gatcatcctg tctccctcgc
    14161 ggtgggggtc caccgatcgg tggacggcgg gttcagtcgt tcgccgctgc cggggacggg
    14221 ggcccgacca gcagcatcga acacatgatg aatcttccag tacgcgtggc ccggtggagc
    14281 gccgggcacc cctggcgggc gatcgccggg tggttcctgt tcgtcgcgct gtgcctcggc
    14341 gtgggcatct cggtcggcgg ccacgccgcc acgtccgcgg acttccgggt cggcgaggcg
    14401 ggacgggcgg aggcgatggc ggccgagggc gggctggaga acaggcccgt ggagcgggtg
    14461 atgatctcgg gcgaggggcc cagggacgcc gccgcgcgcg acgtcgccgc ccggatgaag
    14521 gggctgcccg aggtcgagtc ggtcgccgcg ccggtgcggt ccgccggggg cgacgtcgtc
    14581 cgcgtcgatg tgacgctcaa ggggcccgag ctggacggac gcaagcacgt cgagccgctc
    14641 cgggcgcaga ccgccggcgt ccaggccgcc tacccggggc tgcgggtggt ggagaccggc
    14701 gggccgtccg tcagcaaggg cgtcgaggaa ctgcgcgggg aggacctctc gcgcaccgaa
    14761 gtgatcgcgc tgccggtgac gctgctcacg ctgctgctgg tcttcgggtc ggtggcgctc
    14821 gccgtggtgc cgctgctgct ggcgctgacg tcgatcgtcg cggcggtggg cctgtcgatg
    14881 ctggcctcgc acgtgttccc ggacgcgggg gtcggcacga acgtcatcct cctgatcggg
    14941 ctggccgtcg gcgtcgacta cacgctgttc tacctcaagc gggagcggga ggaacgggcc
    15001 cgggcgggcg gacggctcag cccccaggcg gtggtggagc tggcggcggc gacctcggga
    15061 cgcgccgtcg cggtgtccgg gctcgcggtc gcggtgtcga gcgcgacgct gttcctggcg
    15121 gacgacgtga tcttctcctc gatcgccacc ggcgcgatcg tggtgacggt ggtcgcggtg
    15181 gccagttcga tgaccgtcct gccggcgctg ctcgcgaagc tcggcgcgcg ggccgaacgc
    15241 cgccgggagc gcagggcgca gcgcggcaag gccgtccggg cgcgccggga ggagggcgcc
    15301 ggccgcatca ccacggcgct gctgcgcccc accgagaagc gccccgcgat cacgctggcg
    15361 gtcgccgtgc tggcgatgct cgcgctcgcg tccccgctgc tcggcctcaa gctcaccgac
    15421 atgggacggg agacccaccc gcgcagcatc cccgccgtca aggcctacca ccagctgaac
    15481 gcggccttcc ctgagctgaa gtccacgcac caggtcgtcg tccgcgccga cgctggaggg
    15541 gcggccgagg tgcgcgccgc actcgacgac ctctcccgcc ggacgcacca ggactcgcgc
    15601 ttcacgggca agccgtccct gcgcacgtcg gcggacggcc ggatcagcct cctggagctg
    15661 cccgtcccgc actacggcag cgaggacgcg gcacgcgcgt ccctgcgcga cctcaggaag
    15721 gagtacatcc cggcgaccgt cggacggctg gacgcggacg tcgcggtgtc cggggacgtc
    15781 gcccgctaca ccgactaccc cgaccaccag aagggcaagc tgccgctgat catcgcgacg
    15841 ctgctgctgg tgacgttcgc gatgaccgtg tgggcgttcc ggtcggtggt gctcgggctg
    15901 gtcggggtcg tgctgaacct gctgtcggcc gccgcctcgc tcggcgtgct ggtcgcggtg
    15961 ttccagaaca cctgggcgga ggggctgctc ggcttcacct cgacggggtc gatcgggtcg
    16021 cgcgtcccgc tgctgctgtt cgtgatcctg ttcggcctgt cgatggacta ccaggtgttc
    16081 gtgatcagcc gcatccggga ggcggcgctc gccggggtgc cgacccggcg ggccgtcctg
    16141 gacggcgtcg gcggctccgc gcgggtcgtg acgagtgcgg cgttcgtgat ggtgacggtg
    16201 ttcgcgagct tcgtgccgct gcacatcatc gaaatgaagc agatggggtt cagcctcgcg
    16261 gtcgcggtgc tgctggacgc ggcgatcatc cggatcatga tcctgccggc gacgatgctg
    16321 ctgctcgggg agcggagctg gtggccctcg cgggggatgc gccgggccgg ggcggcggcg
    16381 gtgcgtccga ccgaaaaagt aggctgaccg gcatggacgc gtggccgcag cacgacgatc
    16441 ggcgccaggc ccgcaacctc gtccggtggt acgccgcgct gtgggtggtc gggggactgt
    16501 gcccccaggt catcgcggcg atcgacgacc acggcggggt gcgggtctgg gggatcgtgc
    16561 tgccggtcgc gctcggcgcc tgctacgcgg tgacggcgcc gctcccgcgc gtgctgccgc
    16621 cgccggtgtt cctctgcctg ctcgcggccg ggatcggcgc cgagtcctac gtgcgggcgg
    16681 gcgccgcctc gctctacatc gcctccctcc cgcacttctg gatcctcgcc gggaaccccc
    16741 ggcgggcggc cgcgctgagc ggcgccgccg gggtgctgac gctggtgggg gaggccgcgc
    16801 ggggcgggga cgtcccgtcc ggcaacatgc tcttcaccgt gagcggcttc gtggccgggc
    16861 tgctgctcgg gctggccgcg taccggtacg tgcggcagac cgaggagcgg gcgcggcggc
    16921 tcgccgccga cctggcggtg gcgcagcggg agctggccga ggcgaaccgg cggcagggcg
    16981 cggcggagga gcgcgagcgc ctcgcgcgcg agatccacga cacgctcgcg cagggcttcg
    17041 cgtcgatcat cgtgctcgcg gaggcggccc gcgcggggct cggcgccgaa ccgggccgca
    17101 gcgagcagca gctccgctcg atcgagcgga cggcgcggga caacttcgcg gaggcgcgcg
    17161 ccctggtcga ctccgcgcgc cgcgacggcc ccgcgcaggg ccccgtcgcg gcgacgctcc
    17221 gccgcgttct ggaccgcttc accgaggaca ccggcatccc cgtcggcgcg gagctgcccg
    17281 acgtcgagtg cgaccagccg gcccggatcg cgctgctgcg ctgcacgcag gagtcgctcg
    17341 cgaacatccg caagcacgcg gacgcgtcgt cggtcggcgt cgtgctggag cggtacccgc
    17401 acggcgtcga gctggagatc accgacgacg gccgcgggtt cgtggtcggc gcgtccagcg
    17461 gcttcggcct ggagggcatg cgccggcggc tggccgagct gggcggggag ctgaccgtca
    17521 ccagctcggt cggcgacggc acccggatcc tcgcgatgat cccgacgtcc cccgtggatc
    17581 cgacgagcac gcagaccccc gacgaccccg caggagtgag atgaccgacc gcacgctccg
    17641 cgtcatcgtg gtggacgacc acacggtgat gcgcgccggg gtggtggcgc tgctcgccac
    17701 cgagcccggc atcgagatcg tcggggaggc gggcgacggg cgcgcggccg tcgaactcgc
    17761 cgagcggctc cgtcccgacg tcgcgctggt cgatctgcgg atgcccgtcc tggacggggc
    17821 gagcgcgacc gccgagatcg tcgcgggcgg gtccgggacg cgggtgctga tcctcaccac
    17881 ctacgacacc gacgccgaga tcgagcgggc gatcgaggtg ggcgcggtcg gctacctgct
    17941 caaggacacc acccgcgagc ggctcgccga cgcgatccgg tcggcggcgc gcggtgagac
    18001 cgtgctcgcg ccccgggtcg ccgagcggct ggtggcgcgg atgcggcggc ccgcgccggt
    18061 gccgctcacc gcgcgggagg tggacgtgct gaacggcgtc gccgacggcc tctccaacgc
    18121 cgacatcggc cggcggctcg tcatcgcgga ggcgacggtg aagacgcacc tgctgcgcgt
    18181 gttcgcgaag ctcgacgtca gcgaccgcac gcacgcggtg gtcgtggcga tggagcgcgg
    18241 gctgctgccc cgcccgcgct gaggcccggt cgtcaggctc ggctgaggtc ccggaggctt
    18301 cgccgcgcga acgtctgaga aatgtcacgc gggggtccgg gaaggtggcg cgggcggggt
    18361 cctacgatcg ccgtatggag tacgaggtgc gcctggcgcg gccctccgac ctgccgggcc
    18421 ttccggcgat cgagatctcg gccgaccggc tgttcgcccc gctcgggatc gtgttcccgc
    18481 cgggcccgac ggtgatcgag cagatggccg gcgcggacgc ggagatcctc gtggcgggcg
    18541 acccgccggt ggcgttcgcc gccgtcgagg acgtggacgg cgcgccccac ctggagcaga
    18601 tcgccgtccg gggcgacctg gtggggcggg ggatcgggac ccggctgctg cgggcggtgc
    18661 gcgagcgcgc ggccgccgcc ggtgcgccgg gcgtgagcct gctgacgttc cgggacgtcc
    18721 cgtggaacgg gccatggtat gcccggcagg ggttcgccga acttcccgag cagcgctggg
    18781 gccctggcct gcgcgcctac tggaaggccg agatcgaggc ggggctgcac gacctcggcc
    18841 cacggctgat gatgtgggcg ccgtccggct gagcgccgcg ctagcaccgc ctcgcgcacg
    18901 taatgtggtt ccccggaacg cgtcgggcac ggggtgcgcc gctaaaaaat ctacaacgta
    18961 aaggtgggaa ccggtgacgt cgcgcgagcg tcagcctgag ggagccggag ggggacgatg
    19021 acgggtccgg ggtcatgggt gcggtggatg cgcgggcgtt tcggcgagcg ggggctcgcg
    19081 ctgaccgcgc tggtgggcct gctggcgctc gcggtcgtcc cgctggtggc gctgccggcc
    19141 gtccggtgcg aggtgttcgg agccgggtgc caccggccgc cgcaggaggt ccgcgccgac
    19201 ccggtgtcgg cgccggggcg ccagctcacc cccgtgcagg cggcgacccg gggcggctac
    19261 gtcgcgctcg gcgactccta ctcctccggc gtcggcgccg aggcgaccat cggcgacaac
    19321 aacccgctgg agcgctgcca ccggacgtcc aaggcgtact acaacgaggt ctccaaggcc
    19381 ttcccgttcg cgaagggcac ctcgttctgg gcgtgctcgg gcgcgaccac ggcggacgtc
    19441 cgcaacggca ggcacggcga gccgtcgcag ctcggccgcc tcaacgccga cacgagcctc
    19501 gtcacgctga gcgtcggcgg caacgacatc gggttctcca gggtcgtcgc cgggtgcgtg
    19561 gtgaagctgc cgtggagcag gagctgcttc aggcagggcg acgacatcgc caagaagatg
    19621 tccgacctgc gccgcaacct gcccgagctg atcggccaga tccacgcccg cgcgccgcgc
    19681 gcccgcatca tcctcatggg gtacccgaag gcgttctccg aggtggacgg caccggcggc
    19741 gacaacctgc gggtgtcgga gcagcagtgg ctcaacgccc gcgcctacga cctcgggcag
    19801 ctcatccggg cgagcgccgc cgaggccgac cgccgcatcg ccgcccggca ccagcagggc
    19861 agcgtggagt tcgtcgactc ctacagcgcg ttcgcgggcc acgaggtcgg cagccgccag
    19921 ccgtacatga acggcctcac ggtgaacctg tcggcgctgg aggccgagcc gcgcagctac
    19981 caccccacgg tgagcggcca gcacgccctc gcggggctgt tcatcgagca ggtcaagaag
    20041 gggccgggcc gccccgtctc ctagcgggac gtctcctagc gggggaggga gcgttcggcg
    20101 gcgtcggcgg cgaggcgccg cacaggcacc ctggcctccg cgttcaccgc gcggaacgtc
    20161 aggacgcgcg ggcgcggaac gcggcgcggt aggactgcgg ggacgcgccg acgcggcggg
    20221 cgaagtgggc gcgcagcgtc accggggacc cgaagcccga ctcggcggcg acccgctcga
    20281 ccggcaggtc ggtgctctcc agcagctgct gggcgcggtg gacgcgggcc cgcgacagcc
    20341 accgctgcgg cgtcgtcccg gcctgctctc ggaaccggcg ggtcagggtg cggacgctga
    20401 cggaggcgtg ccgggcgatg tcgtccagcg tcagcgggcg gttcaggttc gcctccagcc
    20461 aggcgagcgt gggctggagc gcggtgtcgc cgtccggggg gtcctcgtgc cggatgaact
    20521 gcgcctgccc gccgtcgcgc tgcggcggca tgatgatccg gcgggcggtg cgggcggcgg
    20581 tcgcggcgcc gtggtcgcgg cggacgacgt gcaggcacag gtcgatgccg gcggcgacgc
    20641 ccgccgaggt gagcacctgc ccgtcgtcca cgtacaggac cgaggcgtcg acctcgacgc
    20701 gcgggtgcag ccgggcgagg cggtgcgcgt acatccagtg ggtggtggcg cgccgcccgt
    20761 ccagcaggcc ggcggcggcc agcacgaacg cgcccacgca gatggaggcg atccgcgtgc
    20821 cgcgctccgc cgcgtcgcgc agcgcgtcca gcacctcggg cggatgctcg gcagggtggt
    20881 cgtagggctg gtcgtggccg gggacgacga tcgtgtcggc cgtggcgagc gcgtccaggc
    20941 cgaagggggg ctcgacccgc atccgcccgc ccgtcgccga ggtcgccgcg ccgcccggca
    21001 gcccgcacac ccgcgtctcg tacaggggga cgtcccggtc ggtggtggac gtgccgaaca
    21061 cctggccggg caccgccagg tcgaacgcca ctaccccgtc cagcgcgagc accgcgacca
    21121 catgcatggc cagaacgtag cgcaccacgt cgctccggac actggccggg gtcccggacg
    21181 cgtcgggatg atcatgccaa tcgagcagag gagggtccct catgaccgac acggccgacc
    21241 ggttcgccga gttcgcgatg cccgacaccg acctgacccg cgcggtccac gacctcgcct
    21301 tcgccgccga gctgcgcgcg ctcgcccacc acagcgtgcg ggtgtacctg ttcgggcggg
    21361 cgctgggcga ggcgcggggg ctgcgtcccg gcgacgccta cgacgacgag ctgctgttcg
    21421 tggcgtgcct gctgcacgac atggggctga ccgagcaggg cgacggcgac cagcggttcg
    21481 aggtggacgg cgccgacctc gccgccgggt tccttgaggg gtacggcgtc gcgccggacc
    21541 ggatccgggt ggtgtgggag gcgatcgccc tgcacaccag cgtgggcatc ccgccgcgga
    21601 tgcgtcccga gatcgcgctg accagcgccg gcgccggcgc ggacatcgcg gggttgcagg
    21661 cggacaggct cccggacggc tacgccgacc gcgtgcacgc ggcgtacccg cggctggagc
    21721 cgggcggcgg gctcacccac ctggtcgtcg accagatcgt ccggaacccg cgcaaggcgc
    21781 cgctggggac gctgccctac gagatcgcgc ggcagctcgg cgcggacatc cccctcccgt
    21841 cgtggacgga gcaggtcggg ggagcgtggc gcggggtcgc ctgacaccgc gcggcggcgc
    21901 cgggacggga tcgcccgcgc ccccggggcg acgggggcgc gggcgacgct ccgacggtcc
    21961 tggccggacc ggtccgctca ggtcgcgagg accgcctgga ggaagtcccg ggtgcgctgc
    22021 tcggacggct cgccgaacat ctgctccggc gggccctcct cgacgatctg cccctcgtcg
    22081 aacatcagga cccggtcgga gatgtccttg gcgaaggtca tctcgtgggt gacgcacagc
    22141 agcgtgaggt cgctctgccg ggcgatgtcg cgcagcaggt cctggacgcc gacgaccagc
    22201 tcggggtcga gcgcggaggt cacctcgtcc agcagcagca cctgcggctc catcgccagc
    22261 gcccgcgcga tcgcgacgcg ctgctgctgg ccgcccgaga gctgcgacgg atgcgcgtcg
    22321 atcttgtcgg cgagcccgac caggtcgagc aggccgcggg cgcgctcgac ggccgcgtcc
    22381 ttgggcaccc cgagcacccg catcggcccc tcggtgaggt tgcgcagcac gttcatgttc
    22441 gggaacaggt tgaactgctg gaacaccatc ccgatccgct tgcgcatctc gtgcaggtgc
    22501 ttctggttcg ccgggacgcg cttgccgccg cggtccatgt gccacagcgg gtcgtcgccg
    22561 acgaagatca ggcccccgtc gggcttctcc agcgtcatca gcagccgcag gatcgtggtc
    22621 ttgcccgacc cgctcggccc gatgagcgtc acccgctcgc ccggcgcgac cgtgaagtcg
    22681 agctcgcgga gcacggtgtt gctcccgaac cgcttgacca ccttctcgaa gcggatgccg
    22741 ggcgcgtcgc cgcgcacggg cgccgcgtcc ttctctggtg tggtgtcagt tggtggcata
    22801 gtgcctctcc aggcggcgga ggagaatcga cgagatgacg ctgaccagga tgaacagcac
    22861 gcccaccatg gtcatcggct ccaggtactc aaacgtcctg gcgcccaccg accgcgcgga
    22921 ggtgagcagc tcggggacgc cgatcgccag cagcagcggc gagtccttga acatggcgat
    22981 gaggtagttc ccgagcgtcg ggatcacctt gcggaacgcc tgcggcagga ccacgtccag
    23041 ccacacccgc gtctgcggca ggttcagcgc cttcgcggcc tcccactgcc cgcgcgggac
    23101 gtcggcgatc ccggcccggt acacctcggc catgtacgtc gagtagtgga tgccgagcat
    23161 gagcacgccg acggtcagct tcccgaacgt caggccccag gtgggcagga cgtagaaggc
    23221 gaagaacagc tgggggatga gcggggtgca ccggatgaac tcggtgaccc accgcaccac
    23281 ctggcggacg atcacgttcg gggtgcgccg cagcatcgtc cacaccaggc cgaggacgac
    23341 cgcgatcagg tagccgagca gcgtcgcgat cagcgtgtag cgcaggcccc tcagcaggtc
    23401 ggggatgatg tcgccggtgt agctccagtc ccattccatc agcgcgccac ccccgctccg
    23461 ggcgcgccgg cggcgaccgt gccgagggcg ggctcacgcg aggggcgccg cccgagcatg
    23521 cggtcgacgc ggcgctcggc gaaccggacg aacagctgga ggatctgcgc gacgacgaag
    23581 tagaggacga gcaccagcga gaacgacgcg acggtctcgc ccgtgctgct ctggaggttc
    23641 ttggagaccg tcgtcaggtc ggtcagcccg accagcgaca cgatcgccgt gcccttcatc
    23701 aactcgatga gcaggttgcc gaagggcggc agcatcagcg cgaacccctg ggggagcagg
    23761 acgcgccgca tccgctgcaa cggggtgaag ttcagcgcga ccgtggcctc gtactgcgcc
    23821 cgcggcaccg ccttgatcga gccgcgcacg acctccgcgc cgtaggcgcc gatgttcagc
    23881 ccgagcgcga gcaccgccgc gaccatcgtc gagttcagcc tgataccgac cagcggcagc
    23941 gcgtagaaga accagaacag cagcaccagc gtcgcggtgc cgcggaagaa ctccacgtac
    24001 acgcggttca gcacccggat ccaggcgtgc cgcgaggtgc cggccagccc gaacaccagg
    24061 gcgagcacca gcgccacgcc gctgccgtac accgtgagct ggagggtgag ccacgcgccc
    24121 ttcagccact gctcgtagcc gtcgaggact tcggacacct gatcatccct tgcagaactt
    24181 ggcggctgtg tcggccgccg tcgggatctc cgcctgggtg aacccgaacg gctggaggat
    24241 cggcagcagc cggttgccct gcttcagttc ggcgagcttg ccgttgaagg cggtcagcag
    24301 gtcgttgtcg gccttgcgga acgcgaacgc gcccgcgccg aactgctcct tgccgtcgat
    24361 gaccggcgtg aacggcgcgg tgacctcgta gggctcgcct tcgtgcttgg tcagcaggtt
    24421 cgcgagcgag atacgggtga gccagatgca gtcgacgcgt cccgccttca ggccctcgaa
    24481 tccgctggcc tggtcggcga acacctggat gttgcccttc ttcacgccgc tcttctccgc
    24541 gtagccctgt tcgacggcgc cctccagcac ccccaccttc acgcccttct taccggggtc
    24601 gtcctgcttg agcagcccct tggggttgcc cttgcggacc atgaacgcgc tcttggccac
    24661 atattccggg tcggagaagg ccaccgagtt gcaccgctcg ggcgtgatga acattcccgc
    24721 cgcgacgacg tcgaaccgtt tggcgttgag cccggcgatg aggccggaga aatcgacctg
    24781 gacgcccgtc accttgtcga tcccgagttc cttgaagatg acccgcgcga gttcgggcgc
    24841 ctccccggtg agcttccccg acttgtcggt gtagccgtag ggcgcctcgt tggcgaagcc
    24901 gaccgtgatc ttgccggcgt ccttggcctt ctggagcgaa ccgccgcccg acttctcctc
    24961 cttcggatcc gtcgtcgagc agcccgcggc ggccagcggc gccgccgcgg acagcaggac
    25021 ggcggtgcgc aggaagtcgc gtctcgagga agtcatcgtt gaactcctgg atggtgtgcc
    25081 gccgcgcccg cggggggccg gacgcccccc gcgggcgcgg ggatgatcgg tcggggttat
    25141 cgaattgttg tcaggcgacc ggcgtgaagt cgcgcgcccc gatgaacgag ggacgcggcg
    25201 cgggcgccgc gaacggctcg acacaggtgt tctcgacgct gttgaacacg atgaacacgt
    25261 tggagcgcgg gaacggggtg atgttcccgt tcgagccgtg catgcagttg cagtcgaaca
    25321 tggtcgccga gcccgccggg cccgtgaaca gctcgatccc gtgcttgtcg gccaggatgg
    25381 acaggctgcc cgggtcaggc gtgccgatct cctggccgcg cagcgattcc ttgtagtggt
    25441 cggacggggt ctccccgacg caggccacga aggtcttgtg cgagccaggc atgatcatta
    25501 gcccgccatt gtgcacgaag ttctcggtga gcgcgatgga aatgctcacg gcgcgcatgc
    25561 gcggcatgcc gtcctcggcg tgccaggtct cgaagtccga gtgccagtag aagtccttgc
    25621 cggtgaaccc cggcttgtaa ttgacccggc tctggtgcac gtagacgtcg gagccgagga
    25681 tctgccgggc ccggccgacc acccgcgggt cgcgcacgag ctgcgcgaac acctcactga
    25741 tccggtgcac ctcgaagatg gagcggacct cgtcggagcc gcgctcggtg accgtgcgct
    25801 cgtcggcgag gatcgcgggg tcggcggcca tccggcgcag ctcggcgcgg tagtcctcga
    25861 cctcggcggg cgtcagcagc tcctcgacgg tcaggtagcc gttggcgtcg aaggagtcga
    25921 gcgtggcggc gtcgacgggc ccgtcctgcg gcgccccgta cacgacgggg tcctgccggt
    25981 agagcagggc ggcctcggcg gccttgcggg tgggataggc gtcgtcgatc gtgggatggg
    26041 actcgatgat gctcatcagg cgtcctcctc cgtgagcagc gggtagatgc cgttctcgtc
    26101 gtgaacctcc cggcccgtgc agggcgggtt gaagacgcag acggtccgca cgtcggtgtg
    26161 ggcacgcagg gtgtggtgct cgtgcccgtc cagcaggtac atcacgccgg gttcgatgcg
    26221 gtgcttctcg ccggtctcct cgttgatcag ttccccttgg cccccgatgc agtagacggc
    26281 ctcgatgtgg ttcgcgtacc acatgcgcgt ctccgtgccg gcgtacagga tggtctcgtg
    26341 cagcgagaag cccacgccct ccttggccag cacgaagcgg cggctgcacc aggtctcggc
    26401 acgcacgtcg cgctcggtgt cgatgatctc ctcaagggaa cgaacgatca tgaatctcct
    26461 ctttccgctg gagccgtgac ggtgtcggtg gggcgggccg ggcccgcccg ggcgtgggtc
    26521 agaccgccac ggtggagcgg acggcctcga ccgactcggc gaggatctcc aggccctggc
    26581 cgaggtcggc ctcgctggtg gtgagcggcg gcagcagctt gaccacctcg ctctccgggc
    26641 cggaggtctc catcagcagc ccccggcgga acgcctcctc gcacaccttc ggcgcgagtt
    26701 cggcgtccga catcaccagg ccccaggcga ggccccggcc gcggacggag tcgaccgccc
    26761 cggcgtgctg gagcgcgatc gcgttcagcg ccgtctcgac ctgctggccc ttggcgagcg
    26821 tctgcttctc cagcccggcg cccacccagt actcctccag cgcggcgacg gcggtcacga
    26881 acgccgggtt gaagccgcgg aaggtgccgt tgtgctcgcc cggctcccac acgtccaggt
    26941 cgcggcgcat cagcgtgacc gcgaacggga gcccgtagcc gctgagcgac ttggacaggc
    27001 agacgatgtc gggcgtgatc ccggcgtcct cgaagctgaa gaacggcccg gagcgcccgc
    27061 agcccatctg cacgtcgtcg acgatcagca ggatgtcgtg gcggcggcac aggtcctgga
    27121 ggccgcgcag ccactcggcg gtcgcgacgt tgatgccgcc ctcgccctgg atcgtctcca
    27181 cgatcacggc ggcgggcttg tccaggccgc tgccgctgtc gtccagcatc gtctcgaaca
    27241 gcaggaagtc gggcgtgcgg ccgtccaggt agttgtcata gggcatcgcg acgccgtgtc
    27301 cgagcggcac cccggcgccg gtgcgcttca tcgagttgcc cgtgacggcc agcgcgccga
    27361 gcgtcatgcc gtggaaggcg ttggtgaagc tcacgatcgt ctcgcggccg gtgtacttgc
    27421 gcgccagctt cagcgcggcc tccaccgcgt ggttgcccgc gggccccggg aactggacct
    27481 tgtagtccag cccgcgcggc gtgaggacgt actcgttgaa ccgttccagg aagtcgcgtt
    27541 tcgcggtcgt gtacatgtcg agcccgtgca cgaccgcgtc accggcgagg tagtcgatga
    27601 gccggcgttt cagttcgggg ttgttgtgcc cgtagttcag cgtgccggca ccggcgaaga
    27661 agtcgaggta ggtgcgtccg ttctcgtcgg tcatgtggct gcccttggcg gtcgtgaaca
    27721 ccgtgggcca tcctcggcaa tagccgcgga cttccgattc catgcgagcg aaaacgtcca
    27781 tggtctgcct ccggcaggtg tggatgggag cggggttgcg tgtggacgga caaagtgacg
    27841 gacgggtgga cggtcaggtg gacggacggg tcgcgtagcg gttcaagcca tcggtcggga
    27901 gcgaggagtc ggggacggtc gggtcgggaa tgcgggctga tcgggcgagc cggtcggtgc
    27961 ggtcgatccg tccgggcgac ggggcgtccg cgatcgccgc ggcggtggcc gcgcgggcga
    28021 tggggccgct gccggaacat ccgcctagtt cgcgccgggg atcgggccga ttcggaacag
    28081 gacctcgggc tcgtggcccc tgccggggaa gtgctccgtc ccgaacaggg ggctgcggtc
    28141 caggtcgcag ccgtgatcgc gggcgaacga ggagaacatc gccgtggacg cctcgttgcc
    28201 cggcgtgacg gtcgcctcca ggtaccggtg gccgcaggcc gcctggcggc gcgcgagccg
    28261 gtccagcatg cggcgggcga ggccccggcc gcggtaggac ttgtcgacgg ccacctgcca
    28321 cacgaagaac gtgtcggggc gggcgggccg cacgtaaccg gtgatgaacc cgcagagcgc
    28381 ggctccgtcg cgcgccacca cggaggtgtc ggcgaagtcg cggcaccaca gcgtgtagct
    28441 gtagggcgag ttgacgtcca ggacgtggga ctcgcgtgcg atccgccaca gcccggggcc
    28501 gtcggtgagg ctcggctcct ggagttgcac gtccgcgttc gtctcggtcc gttcggggcg
    28561 tcgggtcggt gattccaggg gttgcgctgc catgtccagg caacttagcg aatctcggcg
    28621 cgtgatcgct ccggaatgtt atctgcgaga tgtttaggat gtacccgcag cgggtatggc
    28681 agtaggcttg ccaatttcgg aagtatttcg acggcgttaa ggccgtgtcg cggcgcgcat
    28741 ttccccctgt tatccaggcg ggactgccga atgggcggcc gacccttcgt gcggcccatc
    28801 tgcccgtcac tctagtcctt actcatggtg cgggaagctg aattttgtat cggttctgtg
    28861 aggtgaatca ctaagatttg ctgacaacgc gccggtgtgt gggggcgtcg tcacgtgtct
    28921 gcggaggtcg gacgggtcgc cgtcgcgctg ggacgggtgg ggatcaaggg atgaacccgg
    28981 gcatcccggc tcgactcaca ctcaccttgc gacgagacat gccgtctgtc caggcaacgg
    29041 tttgcttgcc ggacggtaag agttcggtgg gttttacgga cgtcttcccc tgccctcggg
    29101 gccgcgcggg aacgcgtggc cccggcccct tccgggtcca ccgcccggcg ggttgcggtg
    29161 gccccggaat cgcggcttgc tggaagcggt caggcggctt ccggctgatt ttcagagtgc
    29221 attcagcggg cgttcgcgaa acggtcggtc gcctcgatga gccggtgcag gattcccggc
    29281 tcgctgtagg cgtggcccgc gtcgtccacg atgtggaaat ccgcctccgg ccacgcccgg
    29341 tgcagatccc acgccgtcgc cgcgggcgtg cacacgtcgt agcggccctg cacgatcacg
    29401 gccgggatgt ggcggatccg gtccacgtcc cggatcagct ggtccggctc gaagaacccc
    29461 tcgttgacga agtagtggtt ctcgatccgc gcgaacgcga ccgcgtagtc gggctccgcg
    29521 aacgtctccg ccagcgcggg gtcgggccgc agcgtcaccg tcgacccctc ccacgtcgac
    29581 cacgcctgcg ccgccgccac ccggacggcg cggtccgggg agttcagccg cgtgtggaag
    29641 gccgcgatga ggtcgtcgcg ctcgtcctcg gggatcggct cgacgtagcg ctcccacagg
    29701 tcggggaaca gcagcgacgc cccctcctgg tagaaccagt acagctcgaa cggccgcagc
    29761 gtgaagatgc cgcgcagcac cagctcgctc acccgctccg gatgcgtctg cgcgtacgcc
    29821 agcgacagtg cgctgcccca gctcccgccg aacaccagcc accgctcgat gcccaggtgc
    29881 tcgcgcagcc gctccatgtc ggcgacgagg ttccaggtgg tgttcgcctc cagcgacacg
    29941 cccgggtcct tggcgtgcgg gacgctccgc ccgcagttgc gctggtcgaa caacacgatg
    30001 cggtaggcct ccgggtcgaa ctgcccgcgg tgcgccgcgc tgcacccgcc ccccgggccg
    30061 ccgtgcacca tcaccgccgg cttcccctcg gggttcccgc agacctccca gtagacgctg
    30121 tcgccgtcgc cgacgtcgag caggccggag tcgtagggct cgatcggcgg atacagggtg
    30181 cgaagttcca tggtgcgcga ttgtcccacc agcgcgtcct caccacgtct tcgtcgcgtt
    30241 cccgtgtcgc gagggtgtga cacgtggcac cgtgggaccg ggcggaacac gcaccgcgga
    30301 aaccgtgatc aggcgtccgg cgtgcgcgaa cgtcccggga ggttcaggaa tccaaacccc
    30361 caaactgggc aaacgctctg cgggagcgca ctagagtgcc tttcgtgagc gaagcgacga
    30421 gccgtagggc gaggagtgaa gcgagcacca tgtccatggc agccccgcga acgcggctcc
    30481 gagccgccag gcgaggaaca aagtgagtga gctgaacgga tcgggtggtt cgcgcgggat
    30541 cccggacgcg ggctccccct ggcccgcgat gggtcgtgac cccgcccagc agccgataca
    30601 gatgtccaag cccggcgagg ccacccgtcc cgaggtggag cagcccgagg cccagccctg
    30661 ggacatcgtc gagcgcctcc gccagatggc cgacctcatc ggcgacgccc tcgccgccgg
    30721 cgagcgcaag gtcagcgaga cgcagaccga gaccgccgcc caggtcgccg ccgtgcaggc
    30781 ggagaaggag tcggcgcagc gggacgcggc cgcggcatgg ggtgaggtgc agcgtgcgcg
    30841 cggtcaggcc gagcaggccg accgccgcgc cgtcgaggcc gagcgccgcg tcgccgagac
    30901 gcagaccgag tccgccgcgc agatcgccgc cgtgcaggcg gagaaggagt cggcgcagcg
    30961 ggacgcggcc gcggcatggg gtgaggtgca gcgtgcgcgc ggtcaggccg agcaggccga
    31021 ccgccgcgcc gtcgaggccg accgcaaggc cgccgacgcc gagcgccgca ccgccgaggt
    31081 ccagaacgag gccatcaccc agatcgccgc gctccagacc gagaaggagg ccgcgcaacg
    31141 cgacgcggcc gccgcctgga accaggccca gcagggccgc gcccaggccg accagctccg
    31201 cggccaggcc gagcaggccc gcatgcaggc cgagcaggcc cgcatgcagg ccgaccaggc
    31261 ccgcggccag gccgagcagg cccgcgccca gatggagcag ctccaggcgc aggtcgagca
    31321 ggccgagcgc cgcgtcgccg aggccgaggc gaccgtccgg caggcgatcc agcagcgcga
    31381 cgccatgagc gaggcccgcg acgacgcgct gcgcgccgtc gaggacgccg tcggcggccg
    31441 ccgctccgcc g
//
