LOCUS       NZ_JAICDG010000001     21086 bp    DNA     linear   CON 29-AUG-2024
DEFINITION  Actinomadura terrae strain OS3-83 contig1, whole genome shotgun
            sequence.
ACCESSION   NZ_JAICDG010000001
VERSION     NZ_JAICDG010000001.1
KEYWORDS    WGS; RefSeq.
SOURCE      Actinomadura terrae
  ORGANISM  Actinomadura terrae
            Bacteria; Actinomycetota; Actinomycetes; Streptosporangiales;
            Thermomonosporaceae; Actinomadura.
REFERENCE   1  (bases 1 to 2300701)
  AUTHORS   Lee,S.D., Yang,H.L., Kim,I.S., Choe,H. and Kim,J.S.
  TITLE     Actinomadura terrae sp. nov. and Actinomadura litoris OS3-89,
            isolated from rhizosphere soil of cactus
  JOURNAL   Int J Syst Evol Microbiol 73 (1) (2023)
   PUBMED   36748505
REFERENCE   2  (bases 1 to 2300701)
  AUTHORS   Lee,S.D.
  TITLE     Direct Submission
  JOURNAL   Submitted (15-FEB-2022) Institute of Jeju Microbial Resources, BioPS
            Co., Ltd., Sancheondan Dongil 16, Jeju 63243, South Korea
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: SPAdes v. 3.13.0
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 141x
            Sequencing Technology             :: Illumina
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_022751215.1-RS_2024_08_29
            Annotation Date                   :: 08/29/2024 06:12:19
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.8
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 8,085
            CDSs (total)                      :: 8,002
            Genes (coding)                    :: 7,936
            CDSs (with protein)               :: 7,936
            Genes (RNA)                       :: 83
            rRNAs                             :: 5, 4, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 3 (5S)
            partial rRNAs                     :: 2, 4, 4 (5S, 16S, 23S)
            tRNAs                             :: 67
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 66
            CDSs (without protein)            :: 66
            Pseudo Genes (ambiguous residues) :: 0 of 66
            Pseudo Genes (frameshifted)       :: 13 of 66
            Pseudo Genes (incomplete)         :: 56 of 66
            Pseudo Genes (internal stop)      :: 3 of 66
            Pseudo Genes (multiple problems)  :: 4 of 66
            CRISPR Arrays                     :: 4
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 21:31:58
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 1560083
            Orig. end                         :: 1581169
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            JAICDG010000001.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..21086
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene-precursor"
                     /region_number="4"
                     /rules="(PT_FPPS_like and not PT_HPP)"
                     /tool="antismash"
     cand_cluster    1..21086
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_FPPS_like and not PT_HPP)"
                     /kind="single"
                     /product="terpene-precursor"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..21086
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:11086](-)"
                     /cutoff="10000"
                     /detection_rule="(PT_FPPS_like and not PT_HPP)"
                     /neighbourhood="10000"
                     /product="terpene-precursor"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..11086)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="(PT_FPPS_like and not PT_HPP)"
                     /neighbourhood="10000"
                     /product="terpene-precursor"
                     /protocluster_number="1"
     gene            complement(686..2581)
                     /gene="pknB"
                     /locus_tag="K2F47_RS06950"
     CDS             complement(686..2581)
                     /GO_function="GO:0004672 - protein kinase activity
                     [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_process="GO:0006468 - protein phosphorylation [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="pknB"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Pkinase"
                     /gene_functions="regulatory (smcogs) SMCOG1030:
                     serine/threonine protein kinase"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019630843.1"
                     /locus_tag="K2F47_RS06950"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="Stk1 family PASTA domain-containing Ser/Thr
                     kinase"
                     /protein_id="WP_242901922.1"
                     /sec_met_domain="Pkinase (E-value: 1.7e-51, bitscore:
                     172.0, seeds: 54, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDATATDPLVGQVLDGRYRIESRVARGGMATVYVARDIRLDRVIA
                     IKVMHPALATDEDFVARFIGEAKSAAALSHPNVVAVYDQVTDGEHVFLVMEYVQGHTLR
                     DALTAAGRFGPRAALEIMQPVLAALGAAHRAGLVHRDVKPENVLITEDGRVKVADFGLA
                     RAESASKMTRTGVIIGTVGYLAPEQVQAGEVDVRTDVYAAGIMLYELVTGRLPHQADTA
                     FAVAYKHVNETVPPPSEAVPGIPRQVDDLVTDATSHNPDRRPRDANQFLAEVAEAYNGL
                     PRDFDQRAQPQTTTVEMHAPSPHTAVLDERDLPRERGRADRAIGAITGRYVLIAVGVVV
                     AMILGWAVWYETSGQYDHVPEKIVGMKLADARAKLKDGGLDVRVTEAVYDDHVRKGEVA
                     KTDPPAGARVAKGETVTLTPSRGRTPREVPDVEGKTLADARKALEGKGFTVGETSTNGS
                     QTVSKDRVISSDPPAGDRRSPDEPVDLVISSGMSMPNLVGIAGDNAANQLRSMGLDVRI
                     DHRKVDGKPPSTVVSQDPPMGTGVSRGDHVTLVVNEDDCKIDIGPVKWGCKKGGEEHIP
                     VPNLMGRNVDEARAALEDSGFKVNVTGIGGDTVRFQNPSSGEAPRGSTITLLRGP"
     gene            complement(2659..3615)
                     /locus_tag="K2F47_RS06955"
     CDS             complement(2659..3615)
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1166: transporter,
                     EamA family"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017585206.1"
                     /locus_tag="K2F47_RS06955"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="DMT family transporter"
                     /protein_id="WP_242901923.1"
                     /transl_table=11
                     /translation="MAEGNVPAPAGIDRLAVAAATVTVVLWASAFVAIRSAGEDYSPGA
                     LALGRMLSGTLVLGVICLVRREGLPSRGAWPGIVTAGVLWFGAYMIALNWGERLVDAGT
                     AALVVNIGPILIALLGGWLLKEGFAPRLLAGMAVSFAGAAVVGLSMSDEGGSSVGGVLL
                     CLAAAVTYAAGVVTQKPTLRHATPLQFTTFSCAIGALACLPFAGQFAGEAADASTGATL
                     NVLYLGVFPTALAFTTWGYALARTSAGKMGATTYAAPALVVLMSWLFLGEVPGLLTLAG
                     GALCLAGVGVSRSTRSLRRRTPVPQAEPEPEPCATTP"
     misc_feature    3610..3620
                     /note="TFBS match to HypR, L-hydroxyproline utilization
                     repressor, confidence: strong, score: 22.05"
                     /tool="antismash"
     gene            complement(3768..4550)
                     /locus_tag="K2F47_RS06960"
     CDS             complement(3768..4550)
                     /EC_number="2.8.1.10"
                     /GO_function="GO:1990107 - thiazole synthase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012853361.1"
                     /locus_tag="K2F47_RS06960"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="thiazole synthase"
                     /protein_id="WP_242901924.1"
                     /transl_table=11
                     /translation="MTIRNETDALEIAGEKLDSRLIMGTGGAPSMAVLREALVASGTEL
                     TTVAMRRVDPSARGSVLDVLRECGVRVLPNTAGCFTAGEAVLTAKLAREALGTDWVKLE
                     VIADERTLLPDPIELVEAAEQLVDDGFTVLPYTSDDPVLARRLERIGCAAVMPLGSPIG
                     SGLGIRNPHNIALIVEQAGVPVILDAGIGTASDAALAMELGCDAVLLATAVTRAQSPAR
                     MAAAMRHAVEAGRLARQAGRIPRRHHAQASSPFEGLAP"
     gene            complement(4552..4752)
                     /gene="thiS"
                     /locus_tag="K2F47_RS06965"
     CDS             complement(4552..4752)
                     /GO_function="GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /GO_process="GO:0009228 - thiamine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="thiS"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012853360.1"
                     /locus_tag="K2F47_RS06965"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="sulfur carrier protein ThiS"
                     /protein_id="WP_242901925.1"
                     /transl_table=11
                     /translation="MKVIVNGEPREVPEGTSVAQAVASVSAAGSGVAAALNDEVVRRSA
                     WEDTPLRESDRLEVLTAVQGG"
     gene            complement(4752..5876)
                     /gene="thiO"
                     /locus_tag="K2F47_RS06970"
     CDS             complement(4752..5876)
                     /EC_number="1.4.3.19"
                     /GO_function="GO:0016647 - oxidoreductase activity, acting
                     on the CH-NH group of donors, oxygen as acceptor [Evidence
                     IEA]"
                     /GO_function="GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA]"
                     /codon_start=1
                     /gene="thiO"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) DAO"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1103: FAD dependent oxidoreductase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017557782.1"
                     /locus_tag="K2F47_RS06970"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="glycine oxidase ThiO"
                     /protein_id="WP_242901926.1"
                     /sec_met_domain="DAO (E-value: 2.8e-72, bitscore: 241.1,
                     seeds: 521, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEIVIIGAGVIGLATAWRAAAGGAAVTLVDPAPMSGASSVAAGML
                     TPVSELTYGEEPLLRLGLASRDRYPAFVAELEERTGLDVAHRTDGILEVAFDSGDLNYL
                     DDLRRFQESLGIPTEALTGRECRRHEPMLAPGVRGGLLAPEDGSVDPRRLTPALLAAAE
                     ALGARLVRRRAAGVLVERDRATGVRLDDGTELRADRVLIAAGPWSGDLEGVPAGVVPPV
                     RPVKGQVIRLRTAVPFLRRCTRALVRGSSVYLVPRADGEIVVGATQEELGFDTRVTAGG
                     LWELLRDAHELLPGITELEFAEVSAGLRPGSPDNAPVMGASALPGLYLGTGHFRNGVLL
                     APVSADILAATLLDEPVPAEAAPFTPDRFSPEVH"
     misc_feature    complement(5861..5875)
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: weak, score: 16.57"
                     /tool="antismash"
     regulatory      complement(5866..5979)
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /regulatory_class="riboswitch"
     misc_feature    complement(5896..5909)
                     /note="TFBS match to ANR, Anaerobic transcriptional
                     regulator, confidence: weak, score: 18.18"
                     /tool="antismash"
     gene            6066..7274
                     /locus_tag="K2F47_RS06975"
     CDS             6066..7274
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Pyr_redox_2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1175: pyridine nucleotide-disulfide oxidoreductase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012889487.1"
                     /locus_tag="K2F47_RS06975"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="WP_242901927.1"
                     /sec_met_domain="Pyr_redox_2 (E-value: 4.4e-45, bitscore:
                     151.0, seeds: 64, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDSVIVVGGGLAGLRAVQGLRDGGHTGAITLVSAEAHLPYDRPPL
                     SKDVLAGSTDDTTLDADWDALRCEVLLGERATGLRLDAPGAGGTVASTAGELRFDGLVI
                     ATGAAPVTLPGDGRQRVLRTVEDALGLRAALVPGARIAIVGAGWIGAEVATTAAAKGCA
                     VTVVEAADTPLASALGPEVGALTAPWYAEAGVELRTGVKVAEVADGGLALAGGERVEAD
                     EVVVGVGVRPVLGWLEGSGLLLERGVVTDASFRASGADGEPRPDVVAVGDCAAWWSARY
                     GRRLLVEHWDAALNAPAVAAAALLGRDAVYDAVPYFWSEQFGRMVQYAGVHGASERLVR
                     RGDPGDAAWAVAWLSGDRLDAILAVGRPRDLVQARRVIAAGTPVDPAALADPDVPVKRA
                     VRA"
     gene            7353..7727
                     /locus_tag="K2F47_RS06980"
     CDS             7353..7727
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012853357.1"
                     /locus_tag="K2F47_RS06980"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="Rv2175c family DNA-binding protein"
                     /protein_id="WP_242902596.1"
                     /transl_table=11
                     /translation="MHATVDSALDPRTDALAGEWLSLRETAERLGIKTNRIKQLISERR
                     LLSIRRDGEPMVPAAFLKDGQVIKGLSGTLTLLSDAGFDEVETVRWLFTADDTLPGTPV
                     EALSENRGTEVRRRAQALAF"
     gene            7856..8539
                     /gene="thiE"
                     /locus_tag="K2F47_RS06985"
     CDS             7856..8539
                     /EC_number="2.5.1.3"
                     /GO_function="GO:0004789 - thiamine-phosphate
                     diphosphorylase activity [Evidence IEA]"
                     /GO_process="GO:0009228 - thiamine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="thiE"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1280: thiamine-phosphate pyrophosphorylase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019630837.1"
                     /locus_tag="K2F47_RS06985"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="thiamine phosphate synthase"
                     /protein_id="WP_242901928.1"
                     /transl_table=11
                     /translation="MSSTVSAHLPTERAVALRARLARARLYLCTDARQRQGDLPEFLDA
                     VLAGGVDLVQLRQKGLEARQELEYLEVFRAACDRHGALMAVNDRADVARAAGADVLHLG
                     QDDLPVPVAREILGEDVLIGRSTHSGEQAGAAAGQAGVDYFCAGPVWPTPTKPGRPAPG
                     PELLEHVAGRRESRPWFAIGGIDLGNLDEVLAAGARRVVVVRAITDADDPGAAAAAFAD
                     RLPPL"
     gene            8611..8772
                     /locus_tag="K2F47_RS06990"
     CDS             8611..8772
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012853355.1"
                     /locus_tag="K2F47_RS06990"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="hypothetical protein"
                     /protein_id="WP_242901929.1"
                     /transl_table=11
                     /translation="MSVGPDDDRPVHLDDDLDVLPDQTSDDTDTGWGEWRGGASDDDRL
                     LEERPPHW"
     gene            complement(8791..9921)
                     /locus_tag="K2F47_RS06995"
     CDS             complement(8791..9921)
                     /EC_number="2.7.11.1"
                     /GO_function="GO:0004674 - protein serine/threonine kinase
                     activity [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_process="GO:0006468 - protein phosphorylation [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Pkinase"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) APH"
                     /gene_functions="regulatory (smcogs) SMCOG1030:
                     serine/threonine protein kinase"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019630835.1"
                     /locus_tag="K2F47_RS06995"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="serine/threonine-protein kinase"
                     /protein_id="WP_242901930.1"
                     /sec_met_domain="Pkinase (E-value: 5.6e-46, bitscore:
                     153.9, seeds: 54, tool: rule-based-clusters)"
                     /sec_met_domain="APH (E-value: 2.6e-07, bitscore: 27.7,
                     seeds: 156, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRKSSSVPAESESAVPHDTSRGRTNPHPPRPAARTGGGAPARAGQ
                     PRAGQPHGGKPRAAEPRPPRAARPARARHSGSALWASDPHALGGYTLLGRLGEGGQGVV
                     YLGQDEDGALVTVKLLRGGVAAGQRARSRFVKEAEAARRVEGRHTARVLDADVTGDRPY
                     IVSEYVEGPSLQQVVEDRGPLPEPRLQKVALRTAAALAAIHRAEIVHRDFKPGNVLLGP
                     DGAKVIDFGIARTADATPVTTGPVGTPAYMAPEQIEDEPVGPAADVFAWGATLVFAATG
                     RPPFGTGPSAAVMRRVTSRPPDLGELDGPLRELAARCLDKNPAARPSARQLVRALRDGQ
                     APAPKPRPKRIPRYRWRMMLALAFVVTAGFALGVLF"
     gene            complement(10001..11086)
                     /locus_tag="K2F47_RS07000"
     CDS             complement(10001..11086)
                     /EC_number="2.5.1.-"
                     /GO_function="GO:0004659 - prenyltransferase activity
                     [Evidence IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /GO_process="GO:0008299 - isoprenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene-precursor: PT_FPPS_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1182: Polyprenyl synthetase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012889490.1"
                     /locus_tag="K2F47_RS07000"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="polyprenyl synthetase family protein"
                     /protein_id="WP_242901931.1"
                     /sec_met_domain="PT_FPPS_like (E-value: 2.7e-47, bitscore:
                     158.1, seeds: 145, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSTSPIRKEVDGALLAFVDRQRPNLLAISDELAPLMAALDALLAE
                     GKRLRPAFCYWGWRAAGAVEEDLGGTPGERLHEGIVNAAASLELLQASALIHDDVMDSS
                     DTRRGQPSMHRRFEALHRAQGWPGPARAFGEGTAILLGDLCLAWSGEMFETCGLDEERR
                     GRGRAVYDLMRTEVMCGQYLDMLEGTRGEATVDTALRVVEFKSAKYTIERPLHLGAALA
                     GGPPEATAALTGYGVPLGIAFQLRDDVLGVFGDPAETGKPAGDDLREGKRTVLVALSLE
                     RATPAQAAALQRRLGDPGLDLPGVDELRQIITDTGGLAACEAMIARYTGDAERVLAAAP
                     FPEEARDALNALAVAATTRRT"
     misc_feature    11129..11147
                     /note="TFBS match to LexA_variant_3, Repressor of DNA
                     damage response, confidence: weak, score: 23.25"
                     /tool="antismash"
     misc_feature    complement(11130..11148)
                     /note="TFBS match to LexA_variant_3, Repressor of DNA
                     damage response, confidence: weak, score: 18.64"
                     /tool="antismash"
     gene            11257..12189
                     /gene="metF"
                     /locus_tag="K2F47_RS07005"
     CDS             11257..12189
                     /EC_number="1.5.1.20"
                     /GO_component="GO:0005829 - cytosol [Evidence IEA]"
                     /GO_function="GO:0004489 - methylenetetrahydrofolate
                     reductase (NAD(P)H) activity [Evidence IEA]"
                     /GO_process="GO:0009086 - methionine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="metF"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019630831.1"
                     /locus_tag="K2F47_RS07005"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="methylenetetrahydrofolate reductase [NAD(P)H]"
                     /protein_id="WP_242901932.1"
                     /transl_table=11
                     /translation="MRRLRPDRPPTVRELLASGRSFSFEFFPPKTDKGARNLWRTIREL
                     EPLRPSFVSVTYGAGGGTRDKTVDIVERIATDTTLTPVAHFTAVDHSQAELRQLIGRFA
                     AVGVRNILAVRGDPPGDPMGEWIKHPDGVEYAADLVRMIRSYGDFSVGVAAFPYKHPRS
                     PDIESDTRHFVAKCRAGADYAITQMFFRAEDFLRLRDRVDAAGCDVPIIPGIMPVTQLS
                     TIERSEQLSGAPFPEDVRARFEAVGDDPEAVRRLGIEHAAELCRDLLDQGVPGIHFITF
                     NKSTATREVYGLLEADGYGARGSVPPMTA"
     gene            complement(12126..12728)
                     /locus_tag="K2F47_RS07010"
     CDS             complement(12126..12728)
                     /EC_number="2.3.1.-"
                     /GO_function="GO:0016747 - acyltransferase activity,
                     transferring groups other than amino-acyl groups [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019630830.1"
                     /locus_tag="K2F47_RS07010"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="WP_242901933.1"
                     /transl_table=11
                     /translation="MRDPKLREIDERAFLRRLGPMLDVYAAAMTPPHEQLPGRHTIMER
                     HAAYPGFRAFVAERRGPLPGLAGPVLGFAYGFHGAHGQWWHDVVHQALAAREGPEHADA
                     WMDDPLEVAELHVHPAAQGRGLGRGLLTALCEGRPERTVVLSTLDLRSETPARRLYRSV
                     GMVDLLTGFEFPGGGPLYAVMGGTLPLAPYPSASSRP"
     gene            complement(12839..13183)
                     /locus_tag="K2F47_RS07015"
     CDS             complement(12839..13183)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019630829.1"
                     /locus_tag="K2F47_RS07015"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="hypothetical protein"
                     /protein_id="WP_242901934.1"
                     /transl_table=11
                     /translation="MSLPSSAPPPPGSLPPPIEAAAAVSLPPTERPNPEYARLYQAYAD
                     AYGSIDRLRNALDASARTFNSTDAWLGPEARQWGGQLDANRNALRKAADRILWDIYDRL
                     NATQRTIAKV"
     gene            complement(13186..14070)
                     /locus_tag="K2F47_RS07020"
     CDS             complement(13186..14070)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="K2F47_RS07020"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_242901935.1"
                     /transl_table=11
                     /translation="MTAQMRSGPAARDPEFRGIDPPALDRVIRQLQDAQNAIQGWLNGH
                     RPPPGVPATGYRQADQVAMWAADQLGMLTRRYNYAITHPDGGGVDVPPVHAPSPKPSPG
                     GSPGPGGGVKPGRPGAPAPRTPSPGAPGTPERRHPVRPPRHTAPPTSRGAGDLGNFPTR
                     QAAAKAARADALAVAAAVRDGDPVPDGVWKHLRANADDPDYTEALYERLGPASAAALVK
                     AAHGDPARLKALRESLGTSSHHLTMDARWLRAFLAEADREGVRPVALQVLTGADLSHRT
                     REALAGLHLKAGG"
     gene            complement(14148..14516)
                     /locus_tag="K2F47_RS07025"
     CDS             complement(14148..14516)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018658568.1"
                     /locus_tag="K2F47_RS07025"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="arsenate reductase family protein"
                     /protein_id="WP_242901936.1"
                     /transl_table=11
                     /translation="MGDNEATELWHNPRCSKSRAAKAALDEAGVPYTERRYLDEPPTAA
                     ELDAALTRIGAEPWDVARLNEPVAKELGLAALEHDRARWIEVMVAHPVLIQRPIILTGA
                     VAVVARDDESVRRALDSR"
     gene            complement(14518..14982)
                     /locus_tag="K2F47_RS07030"
     CDS             complement(14518..14982)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011291495.1"
                     /locus_tag="K2F47_RS07030"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="YbaK/EbsC family protein"
                     /protein_id="WP_242901937.1"
                     /transl_table=11
                     /translation="MHANAERVAKALEAQGAAGKIVELPDSARTAQAAADQLGCEVGAI
                     ANSLVFDADGAPLLVLTSGAHRVDTARVAALVGAAAVRRATPEFVREATGQPIGGVAPL
                     GHPEPIRTLVDVWLDKYDEVWAAGGHPHTVFPTSYEELLRITGGTPAEVG"
     gene            15027..15878
                     /locus_tag="K2F47_RS07035"
     CDS             15027..15878
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012853346.1"
                     /locus_tag="K2F47_RS07035"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="L,D-transpeptidase family protein"
                     /protein_id="WP_242901938.1"
                     /transl_table=11
                     /translation="MRKSAALLIPIVLLAGCKTASDAAPADAGRSSQGRKPPHDRPRHK
                     PKPKPKREPAHKPKTRSTPRPSPTRPPLRAGDRKLRPGAEGADVRELQRRLTSLHYDPG
                     KADGEYGTSTQLAVWAFQAVNRLKPTGTLGPAFWRALDDPKEPRPMARRHEADRVDVDL
                     RRQYLVLYKDGRPRLITHVSSGSGEYYCAKDRGATVARCRYAITGTGDFRTGRRAKGWE
                     ISPLGRLYNPVYFNGGIAFHGALDVPRYPASHGCVRMPMHVAEYFPSLVGTGVAVHVRR
                     PG"
     misc_feature    15028..15044
                     /note="TFBS match to GnfM, Regulator of nitrogen-fixation
                     genes, confidence: weak, score: 21.11"
                     /tool="antismash"
     misc_feature    15979..15994
                     /note="TFBS match to LexA_variant_1, Repressor of DNA
                     damage response, confidence: medium, score: 25.93"
                     /tool="antismash"
     misc_feature    complement(15980..15993)
                     /note="TFBS match to LexA_variant_2, Repressor of DNA
                     damage response, confidence: strong, score: 24.0"
                     /tool="antismash"
     gene            16135..16629
                     /locus_tag="K2F47_RS07040"
     CDS             16135..16629
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012853345.1"
                     /locus_tag="K2F47_RS07040"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="SAV_6107 family HEPN domain-containing protein"
                     /protein_id="WP_242901939.1"
                     /transl_table=11
                     /translation="MSGTTTARGVHSAAQFGPPAPRSRPMPAPRPAHTAVGQLHAARMG
                     LAEAAEATSPAVRYVCAHLAALRAAAAVLASKEPLETHRRGRPRSVWVLLPEAEPALRE
                     WAAFFAAGADKRAAAEAGLPRAVTPREAEELLHDAEVFVTLVEDTLGVTSQPTLPIPEA
                     S"
     gene            complement(16790..17995)
                     /locus_tag="K2F47_RS07045"
     CDS             complement(16790..17995)
                     /GO_function="GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1020: major
                     facilitator transporter"
                     /gene_kind="transport"
                     /inference="COORDINATES: protein motif:HMM:NF017760.5"
                     /locus_tag="K2F47_RS07045"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="MFS transporter"
                     /protein_id="WP_242901940.1"
                     /transl_table=11
                     /translation="MSARPGAEFAKLWTASAVSNVGDGVTVVAGPLLAASLTRDPAQVA
                     LVAFAQALPWPLFSLVSGAVVDRVDRRRLICAVDLLRGAVLAGLALLVAAGAATVPLLC
                     AVFFLVGLGETVADTAAVARLPAIVPPERLAAANARLMATFTVGNQLAAKPLGAWLFAA
                     GAAFPFGFDAVTFVVAALLVASMRRVPAETRGRPPGDRRSLRADIAEGVRWLWSHRLLR
                     TLALSMGVANIAFCSAFSVFVLYAADRLGLSEVGYGLLLTTFGFGGLAGTVLADRLQRR
                     FGATALLRAGLALEAATHLVLASTRHAWVAAAILVAFGVHTMVWGVIATTVRQRATPDR
                     LLGRVGGVYALADSSGAALGLLTGGVLARAGGVTAPYWIAGALTALVTAAAWRPLKEAS
                     RL"
     gene            complement(18369..18863)
                     /locus_tag="K2F47_RS07050"
     CDS             complement(18369..18863)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017622275.1"
                     /locus_tag="K2F47_RS07050"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="transcriptional regulator"
                     /protein_id="WP_067463081.1"
                     /transl_table=11
                     /translation="MPSEYAKALGARLRAIRTQQGLSLHGVEEKSRGRWKAVVVGSYER
                     GDRAVTVQKLAELADFYGVPVSELLPGGAAPSPLGPTPKLVIDLERLQQLPKDKAGPLA
                     RYAATIQSQRGDYNGKVLSIRQEDLRSLAVIYDKSPNELTEELITWGVLDPEARRAVES
                     F"
     misc_feature    18985..19001
                     /note="TFBS match to GnfM, Regulator of nitrogen-fixation
                     genes, confidence: weak, score: 19.64"
                     /tool="antismash"
     misc_feature    complement(19017..19030)
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 12.29"
                     /tool="antismash"
     misc_feature    complement(19018..19031)
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 12.59"
                     /tool="antismash"
     misc_feature    complement(19143..19158)
                     /note="TFBS match to CRP, Cyclic AMP receptor protein,
                     confidence: medium, score: 17.13"
                     /tool="antismash"
     gene            19313..19873
                     /gene="pyrR"
                     /locus_tag="K2F47_RS07055"
     CDS             19313..19873
                     /EC_number="2.4.2.9"
                     /GO_process="GO:0009116 - nucleoside metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="pyrR"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019630799.1"
                     /locus_tag="K2F47_RS07055"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="bifunctional pyr operon transcriptional
                     regulator/uracil phosphoribosyltransferase PyrR"
                     /protein_id="WP_242902597.1"
                     /transl_table=11
                     /translation="MADGDPRPKAVLEGPDIRRALTRIAHEILERTKGGHDVLLLGIQT
                     RGVTLAERLAALLGDVEGRPVPWGSLDVTMYRDDLRMRPARALGRTEVPQDGVDDRVVV
                     LVDDVLFSGRTVRAALDALNDLGRPRAVQLAVLVDRGHRQLPIRADYVGKNLPTSMRET
                     VRVLLGENDGRDAVLLGPAGGDR"
     gene            19870..20811
                     /locus_tag="K2F47_RS07060"
     CDS             19870..20811
                     /EC_number="2.1.3.2"
                     /GO_function="GO:0004070 - aspartate carbamoyltransferase
                     activity [Evidence IEA]"
                     /GO_function="GO:0016597 - amino acid binding [Evidence
                     IEA]"
                     /GO_process="GO:0006207 - 'de novo' pyrimidine nucleobase
                     biosynthetic process [Evidence IEA]"
                     /GO_process="GO:0006520 - amino acid metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1114: ornithine carbamoyltransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012853341.1"
                     /locus_tag="K2F47_RS07060"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="aspartate carbamoyltransferase catalytic subunit"
                     /protein_id="WP_242901941.1"
                     /transl_table=11
                     /translation="MKRHLISAADLTRDDALLVLDTAAELEKVAGRSIKKLPTLRGRTV
                     VNLFFEDSTRTRISFEAAAKRLSADVINFSAKGSSVSKGESLKDTALTLEAMGADGVVV
                     RHGASGAPHRLAGWVQGSVVNAGDGTHEHPTQALLDAFTMRKRLGDLEGRRVTIVGDVL
                     HSRVARSNVLLLGTLGADVTVVAPPTLLPVAINTWPCQVSYDLDAVLPKSDVIMMLRVQ
                     QERMNAAYFPTVREYSRRYGLDGERMAALPDHAIVMHPGPMNRGVEIAAEVADSVRSTI
                     VEQVANGVSARMAVLYLLLGGSEPAIGTEVAE"
ORIGIN
        1 gggtccttgg agtcgttggc gtggacgagt ttgaggcggc cctcgcccac ggtggcgacc
       61 agggcgtcga tggtggcctt gacgccgccg ggggcggcga ggtcgtggcc cgccgcgtag
      121 gcgtggcagg tgtcgaagca gacgccgagc ttcgggtggt gctccagctt ctcgaagaag
      181 gggcccagtt gctcgacctt ggcgcagagc atgttgttct ggcccgccat cggctccagg
      241 agcaggtcgg ggccgtcctc ggggatctcc tccaggaggg ggaggacgtg ctcgcggacc
      301 tgggccatcg cctcgtcgta ggtctgggtg acggaggagc cggtgtggac gacgacgccg
      361 cgggcgccga tcgcgcggcc gcgggtcagg gagtggcgga tggacgcgag cgacttggcc
      421 agggtctcgg ggttcgggga gccgacgttg accaggtagg gcgtgtggac gtagacgggg
      481 acgtcggtgc gctccagcag cttcgcgtcc tcggtgggct tgccctccgg catcgcccag
      541 ccgcgcgggt tcgccacgaa gacctggatg gtctcggcgc cgatctcggc ggcgtacttc
      601 aggccgccgg tggcgaggcc gcccgccacc gggacgtgcg cgccgatcag gctttttggt
      661 gaggtcatag gcggtccagc gtagctcagg ggccccgcag gagcgtgatg gtggagccgc
      721 ggggcgcctc gccggagctc gggttctgga agcggacggt gtcgccgcct atcccggtca
      781 cgttgacctt gaagcccgag tcctccaggg ccgccctggc ctcgtcgacg ttgcggccca
      841 tcaggttggg gacggggatg tgctcctcgc cgcccttctt gcagccccac ttgaccgggc
      901 cgatgtcgat cttgcagtcg tcctcgttga cgacgagcgt gacgtggtcg ccgcgggaga
      961 cgccggtgcc catgggcggg tcctggctga ccaccgtgct cggcggcttg ccgtcgacct
     1021 tccggtggtc gatcctgacg tccaggccca tcgagcggag ctggttggcg gcgttgtcgc
     1081 ccgcgatgcc gaccaggttc ggcatcgaca tgccgctgct gatcacgagg tcgacgggct
     1141 cgtcggggga gcggcggtcg cccgcgggcg ggtcgctgct gatgacccgg tccttggaga
     1201 cggtctgcga gccgttggtg ctggtctccc cgacggtgaa gcccttgcct tcgagggcct
     1261 tcctggcgtc cgcgagcgtc ttgccctcga cgtccgggac ctcgcggggg gtgcggccgc
     1321 gggacggggt gagcgtgacg gtctcgccct tggcgacgcg ggcgccggcg ggcgggtcgg
     1381 tcttcgcgac ctcgcccttg cggacgtggt cgtcgtagac ggcctccgtg acgcggacgt
     1441 cgaggccgcc gtccttcagc ttggcgcggg cgtcggccag cttcatcccg acgatcttct
     1501 cggggacgtg gtcgtactgg ccggacgtct cgtaccagac ggcccagccg aggatcatcg
     1561 cgacgaccac gccgacggcg atcaggacgt agcggccggt gatcgcgccg atcgcgcggt
     1621 cggcgcggcc gcgctcgcgg gggaggtccc gctcgtccag gacggccgtg tggggggacg
     1681 gcgcgtgcat ctcgacggtg gtggtctgcg gctgcgcgcg ctggtcgaag tcgcggggga
     1741 ggccgttgta ggcctcggcg acctcggcga ggaactggtt cgcgtcccgg gggcggcggt
     1801 ccggattgtg actggtggcg tcggtgacca ggtcgtcgac ctggcggggg atgccgggga
     1861 cggcctccga cggcggcggg acggtctcgt tgacgtgctt gtaggcgacg gcgaacgcgg
     1921 tgtcggcctg gtgcggcagc cggccggtga ccagctcgta gagcatgatc ccggcggcgt
     1981 agacgtcggt gcggacgtcg acctcgcccg cctgcacctg ttcgggcgcc aggtagccga
     2041 cggttccgat gatcacgccg gtccgggtca tcttgctcgc ggactcggcc cgggcgaggc
     2101 cgaagtcggc gaccttgacc cggccgtcct cggtgatcag cacgttctcg ggcttgacgt
     2161 cgcggtgcac gagcccggcc cggtgcgcgg cgccgagcgc ggcgaggacc ggctgcatga
     2221 tctccagcgc ggcgcggggg ccgaaccgcc cggcggcggt gagcgcgtcg cggagcgtgt
     2281 ggccctggac gtactccatc accaggaaga cgtgctcgcc gtcggtgacc tggtcgtaga
     2341 cggcgacgac gttcgggtgc gagagcgcgg cggcggactt ggcctcgccg atgaagcggg
     2401 cgacgaagtc ctcgtcggtg gcgagcgcgg ggtgcatcac cttgatcgcg atgacgcggt
     2461 cgaggcggat gtcgcgggcc acgtacacgg tggccatgcc gccgcgggcg acccgtgact
     2521 caatgcggta tcgcccgtcg agaacctgcc ccacgagggg atcggtagcc gtcgcgtcca
     2581 tcgctgcgag tttacggcgc ggcccgggcg gatctcatca gtccggagta tgagcgcatc
     2641 tgcgccgtcg gtcggagttc agggggtggt ggcgcagggt tcgggctcgg gctcggcctg
     2701 cgggacgggg gtgcggcgcc gcagcgaccg ggtgctgcgg gacacgccga cgccggccag
     2761 gcacagggcg ccgcccgcga gcgtgagcag cccgggaacc tcgccgagga acagccacga
     2821 catcaggacg acgagcgcgg gcgcggcgta ggtggtggcg cccatcttcc ccgccgacgt
     2881 gcgggccagc gcgtagcccc aggtcgtgaa cgccagcgcg gtcgggaaga cgcccaggta
     2941 gagcacgttg agcgtggcgc cggtggaggc gtccgccgcc tcgcccgcga actgaccggc
     3001 gaacggcagg caggcgaggg cgccgatcgc gcaggagaac gtcgtgaact ggagcggcgt
     3061 ggcgtgcctg agcgtgggct tctgggtcac cacgcccgcg gcgtaggtga cggcggcggc
     3121 caggcacagc aggacgccgc cgaccgagga gccgccctcg tccgacatcg acagcccgac
     3181 gacggcggcg cccgcgaacg agaccgccat gcccgcgagg agccggggcg cgaagccctc
     3241 cttcagcagc cagccgccga ggagcgcgat gaggatcggc ccgatgttga cgacgagcgc
     3301 ggcggtgccc gcgtccacga gccgctcgcc ccagttcagc gcgatcatgt aggcgccgaa
     3361 ccacagcacc ccggcggtga cgatgccggg ccacgcgccg cgggagggca gcccctcgcg
     3421 gcggacgagg cagatcacgc cgagcacgag ggtcccggag agcatgcggc cgagcgcgag
     3481 ggcgccgggg ctgtagtcct ccccggcgct gcggatcgcg acgaacgccg acgcccacag
     3541 gacgacggtc acggtcgccg ccgccacggc cagcctgtcg attcccgccg gggcgggaac
     3601 gttcccttct gccatgtcac gcaccttagg tctgagatgt ttccatcaac accgaaatgt
     3661 cgcgcaacgt tgcggacgag gggttcgggg ggatgggccc agtctcggtg cgccgaccgt
     3721 gcaggtctag cgactcttgc tatagacgat ctttaaggat ctctacatca gggcgcgagg
     3781 ccctcgaagg gcgaggacgc ctgggcgtgg tggcgcctcg ggatgcggcc cgcctgccgg
     3841 gcgaggcgcc cggcctcgac ggcgtgccgc atcgcggcgg ccatccgcgc gggcgactgg
     3901 gcgcgggtca cggcggtcgc gaggagcacc gcgtcgcagc cgagctccat ggcgagcgcg
     3961 gcgtcgctgg cggtgccgat ccccgcgtcc aggatcaccg ggaccccggc ctgctcgacg
     4021 atcagtgcga tgttgtgcgg gttgcggatg ccgagccccg agccgatcgg ggagccgagc
     4081 ggcatcaccg ccgcgcaccc gatccgctcc agccgccgcg cgagcaccgg gtcgtcgctg
     4141 gtgtagggga gcacggtgaa cccgtcgtcg acgagctgct cggcggcctc gaccagctcg
     4201 atcgggtcgg gcagcagcgt ccgctcgtcg gcgatcacct ccagcttgac ccagtcggtg
     4261 ccgagcgcct cgcgggcgag cttggcggtc agcacggcct cgcccgccgt gaagcagccc
     4321 gccgtgttcg gcagcacccg gacgccgcac tcgcgcagca cgtccagcac cgagccccgc
     4381 gcggacgggt cgacccgtcg catcgcgacc gtggtcagct ccgtcccgga cgcgacgagc
     4441 gcctcgcgca gcaccgccat gctgggcgcg ccgccggtgc ccatgatcag ccgggagtcc
     4501 agcttctcgc ccgcgatctc cagcgcgtcg gtctcgttcc ggatcgtcat ctcagcctcc
     4561 ctggacggcg gtcagcactt cgaggcggtc ggactcgcgc agcggcgtgt cttcccaggc
     4621 cgaccggcgg acgacctcgt cgttgagcgc ggcggccaca ccggacccgg ccgcggagac
     4681 ggaagcgacg gcctgcgcga cgctggtgcc ctccggcacc tcgcgcggct cgccgttgac
     4741 gatgaccttc atcagtgcac ctcgggggag aagcggtcgg gtgtgaaggg ggctgcctcg
     4801 gcggggacgg gctcgtccag cagcgtcgcg gccaggatgt cggcgctgac cggggcgagg
     4861 aggacgccgt tgcggaagtg gcccgttccg aggtacaggc cgggcagcgc cgaggcgccc
     4921 atcaccggcg cgttgtcggg ggagccgggc cgcaggcccg ccgagacctc ggcgaactcc
     4981 agttcggtga tgccgggcag cagctcgtgg gcgtcgcgca gcagctccca cagcccgccc
     5041 gcggtgaccc gcgtgtcgaa gcccagctcc tcctgggtcg cgccgacgac gatctcgccg
     5101 tccgcgcgcg gcaccaggta gaccgacgag ccccggacca gcgcccgggt gcagcgccgc
     5161 aggaacggca ccgccgtccg caaccggatg acctggccct tcaccggccg gacgggcggg
     5221 accacgcccg ccggcacgcc ctccaggtcg ccggaccagg ggccggctgc gatcaggacg
     5281 cggtcggcgc ggagctccgt cccgtcgtcg aggcggacgc cggtcgcccg gtcgcgctcg
     5341 accaggacgc ccgccgcccg ccgccggacg agccgcgcgc ccagcgcctc ggccgccgcc
     5401 agcagcgcgg gggtgaggcg gcgcgggtcg accgagccgt cctcgggggc gagcaggccg
     5461 ccgcgcacgc cgggtgccag catcggctcg tgccggcggc actcgcggcc ggtcagcgcc
     5521 tcggtcggga tgccgaggct ctcctggaag cggcgcaggt cgtccaggta gttcaggtcg
     5581 cccgagtcga acgcgacctc caggatgccg tcggtgcggt gggcgacgtc gagcccggtc
     5641 cgctcctcca gctcggcgac gaacgcgggg tagcggtcgc gggaggcgag cccgagccgc
     5701 agcagcggct cctcgccgta ggtcagttcg ctgaccgggg tcagcatgcc cgccgcgacc
     5761 gacgacgccc cgctcatggg cgccgggtcg accagcgtga cggcggcgcc gcccgcggcc
     5821 gcccgccagg cggtggcgag gccgatgacc ccggcgccga tgatgacgat ctccatgcgc
     5881 gctcccttcg ccggcatgat ccggatcagg tggtggcggt cggcggcccg ctcagccgcc
     5941 ctctcagccc ggtcgcaccg gactcccgcg ctctcgccct ccaccatacg acgtcgggtg
     6001 atatgcgcag ttgtccggat accgatcatg gggctgcggg aggcccccgg ctagggtgga
     6061 cggccatgga cagcgtgatc gtcgtgggtg gcgggctggc ggggctgcgg gcggttcagg
     6121 ggctgcgcga cggcggccac acgggcgcga tcacgctcgt ctcggccgag gcccacctgc
     6181 cctacgaccg gccgccgttg tcgaaagacg tcctcgcggg ctccaccgac gacaccacgc
     6241 tcgacgccga ctgggacgcg ctgcgctgcg aggtcctgct cggcgagcgg gccaccggcc
     6301 tgcggctgga cgcgccgggc gcgggcggca ccgtcgcgtc cacggcgggc gagctgcgct
     6361 tcgacggcct cgtgatcgcc accggcgccg cgccggtcac gctgccgggg gacgggcgcc
     6421 agcgcgtgct gcgcaccgtc gaggacgccc tgggcctgcg cgccgcgctc gtccccggcg
     6481 cccggatcgc gatcgtcggc gcgggctgga tcggcgcgga ggtcgcgacg accgccgccg
     6541 ccaagggctg cgcggtcacc gtggtcgagg cggcggacac tccgctcgcg tccgcgctcg
     6601 ggcccgaggt cggcgcgctg accgcgccct ggtacgccga ggcgggcgtc gagctgcgca
     6661 ccggcgtgaa ggtcgcggag gtcgcggacg gcggcctggc cctggcgggc ggcgagcggg
     6721 tcgaggccga cgaggtggtc gtcggcgtcg gcgtccggcc cgtcctgggc tggctggagg
     6781 gctcggggct gctgctggag cgcggtgtcg tcaccgacgc ctcgttccgc gcctccgggg
     6841 cggacgggga gccgcgtccc gacgtggtgg cggtcgggga ctgcgccgcc tggtggtccg
     6901 cgcggtacgg gcggcggctg ctcgtcgagc actgggacgc cgccctgaac gcgccggccg
     6961 tggccgccgc cgccctcctc gggcgggacg cggtctacga cgccgtcccg tacttctggt
     7021 ccgagcagtt cggccggatg gtccagtacg cgggggtgca cggcgcctcc gagcggctcg
     7081 tccgccgggg ggacccgggg gacgcggcgt gggcggtcgc ctggctcagc ggcgaccggc
     7141 tcgacgcgat cctcgccgtc ggccgccccc gcgacctcgt gcaggccagg cgggtgatcg
     7201 ccgccgggac cccggtcgac cccgccgcgc tggccgatcc ggacgtcccg gtgaagcgtg
     7261 ctgttcgcgc gtagcggaca ctgacctgcg cgaacgggcg ccggacgggt ttgaggcttc
     7321 cgatggcgtg gtatccaggt ggcgtgacgc agatgcacgc gaccgttgac agcgcactcg
     7381 acccccgcac cgacgccctg gccggggagt ggctctccct cagggagacc gccgagcgac
     7441 tcggcatcaa gaccaaccgg atcaagcagc tcatcagcga gcgccggctc ctgtccatcc
     7501 ggcgcgacgg cgagccgatg gtgcccgccg cgtttctcaa ggacggccag gtcatcaagg
     7561 gcctgtccgg gacgctgacg ctcctgtcgg acgcgggctt cgacgaggtg gagacggtcc
     7621 gctggctgtt caccgccgac gacacgctgc ccggcacgcc cgtcgaggcg ctgagcgaga
     7681 accgcgggac cgaggtgcgc cgccgcgccc aggcgctggc cttctagggc gcgaccgggc
     7741 ggacgggccg gcaccagggc ccggtgagag cacgtgacac gattgcgggg tcgcgcgcgg
     7801 catgaggctg ccgcgcggcc ccgcgatccg tatccggaag gaaccgtccg acaccgtgtc
     7861 cagcaccgtc tccgcccacc tgcccaccga gcgggccgtc gcgctccgcg cccggctcgc
     7921 ccgcgcccgc ctctacctct gcacggacgc gcggcagcgg cagggcgacc tgcccgagtt
     7981 cctggacgcg gtgctcgcgg gcggcgtcga cctcgtccag ctccggcaga agggcctgga
     8041 ggcccggcag gagctggagt acctggaggt cttccgcgcg gcctgcgacc ggcacggcgc
     8101 gctgatggcg gtgaacgacc gggccgacgt cgcgcgcgcc gccggagccg acgtcctgca
     8161 cctcggccag gacgacctgc cggtgccggt cgcccgcgag atcctcggcg aggacgtcct
     8221 gatcggccgc tcgacgcact cgggcgagca ggcgggcgcg gcggcggggc aggcgggcgt
     8281 cgactacttc tgcgcgggcc cggtgtggcc cacgcccacc aagccgggac gtcccgcgcc
     8341 cggccccgag ctgctggagc acgtcgccgg gcggcgcgag agccgcccct ggttcgcgat
     8401 cggcggcatc gacctcggca acctcgacga ggtgctcgcg gccggggcgc gccgcgtcgt
     8461 ggtggtccgg gcgatcaccg acgcggacga tccgggcgcc gccgcggccg cgttcgccga
     8521 ccggctcccg ccgctctgat ctcggcccgt tcaggtcccg ttcgcctact ggcggccggg
     8581 gcagccgccg cgatgaccga caatgggatc atgagcgttg gacccgacga cgacaggccc
     8641 gtgcacctgg acgacgacct ggacgtcctg cccgaccaga cgtccgacga caccgacacc
     8701 ggctggggcg agtggcgcgg cggcgcgagc gacgacgacc gactgctgga ggaacggccg
     8761 ccgcactggt gaccctcgtg gcgcggcccg ctagaacagc acgccgagcg cgaaaccggc
     8821 ggtgaccacg aacgcgagcg cgagcatcat ccgccagcgg tagcggggga tgcgcttcgg
     8881 gcgtggcttc ggcgcgggcg cctggccgtc ccgcagcgcg cggacgagct gccgcgcgct
     8941 cgggcgcgcg gccgggttct tgtccaggca gcgcgccgcc agctcgcgca gcgggccgtc
     9001 cagctcgccg aggtccggcg ggcgcgacgt cacgcgccgc atcacggcgg cgctcggccc
     9061 ggtgccgaac ggcgggcgcc cggtcgcggc gaacaccagc gtggctcccc aggcgaacac
     9121 gtccgccgca gggccgaccg gctcgtcctc gatctgctcg ggcgccatgt aggcgggggt
     9181 gccgaccggg cccgtggtca ccggggtcgc gtcggcggtg cgggcgatcc cgaagtcgat
     9241 caccttggcg ccgtccgggc cgagcaggac gttgccgggc ttgaagtcgc ggtgcacgat
     9301 ctcggcgcgg tggatcgcgg cgagcgccgc cgcggtccgc agcgcgacct tctggagccg
     9361 gggctccggc agcgggcccc ggtcctcgac gacctgctgg agcgagggcc cctcgacgta
     9421 ctcgctgacg atgtaggggc ggtcgccggt gacgtcggcg tccagcacgc gggcggtgtg
     9481 gcggccctcg acccgccgcg ccgcctccgc ctccttgacg aagcggctcc gggcgcgctg
     9541 cccggccgcg acgccgccgc gtagcagctt gacggtgacg agcgcgccgt cctcgtcctg
     9601 gcccaggtag acgacgccct ggccgccctc gccgagccgg ccgagcagcg tgtagccgcc
     9661 gagggcgtgc gggtcgctcg cccagagcgc cgacccggag tgccgcgccc gcgcgggccg
     9721 ggccgcgcgc ggcggacgcg gctccgcggc gcggggcttc ccgccgtgcg gctggccggc
     9781 gcggggctgg ccggcgcgcg ccggggcgcc gccaccggta cgggcggcgg gacgcggggg
     9841 atgggggttc gtcctcccgc gggaggtgtc gtgcggcacg gcggactccg actcggcggg
     9901 gacggacgaa gatttcctca tttgtaccgc gtaaccaccg gacgcggcag gggaaccccg
     9961 atcttcgggc cccgtccggc gaagtcaggt gcgtcgtggg tcaggtgcgt cgagtggtcg
    10021 cggcgacggc gagggcgttc agcgcgtcgc gcgcctcctc cgggaacggc gcggcggcca
    10081 gcacgcgctc ggcgtcgccg gtgtagcggg cgatcatcgc ctcgcaggcc gcgagcccgc
    10141 cggtgtcggt gatgatctgg cgcagctcgt ccacccccgg caggtcgagg ccggggtcgc
    10201 cgaggcgccg ctggagcgcc gccgcctgcg cgggcgtggc gcgttcgagg gacagcgcga
    10261 ccaggacggt ccgctttccc tcgcgcaggt cgtcgcctgc gggcttgccg gtctcggccg
    10321 ggtcgccgaa cacccccagc acgtcgtcgc ggagctggaa ggcgatgccg agcgggacgc
    10381 cgtagccggt gagggcggcg gtcgcctccg gcggtccccc ggcgagcgcg gcgccgaggt
    10441 gcagcggccg ctcgatcgtg tacttggcgc tcttgaactc caccacgcgc agcgccgtgt
    10501 cgacggtggc ctcgccccgg gtgccctcca gcatgtccag gtactggccg cacatgacct
    10561 cggtgcgcat caggtcgtag acggcccggc ctcggccgcg gcgctcctcg tccagcccgc
    10621 acgtctcgaa catctcgccc gaccaggcca ggcacagatc gccgagcagg atcgcggtgc
    10681 cctccccgaa cgcccgcgcg gggcccggcc agccctgcgc gcggtgcagc gcctcgaacc
    10741 tgcggtgcat cgacggctgc ccgcggcggg tgtcgctgga gtccatcacg tcgtcgtgga
    10801 tcagcgcgct cgcctggagc agctccaggg acgccgccgc gttgacgatg ccctcgtgca
    10861 gccgctcgcc gggcgtcccg ccgaggtcct cctccacggc gcccgccgcc cgccagcccc
    10921 agtagcagaa ggccgggcgc agccgcttgc cctccgcgag cagcgcgtcc agggcggcca
    10981 tcagcggtgc cagctcgtcg ctgatcgcca gcaggttcgg acgctgccgg tcgacgaagg
    11041 ccagcagcgc cccgtcgacc tccttgcgga tggggctcgt tgacatgccg agatcgtatc
    11101 cacgggacgg ccgccactcg tacgtcataa cgggataaat gcccagttct agctatttaa
    11161 ggggcatacc ggatggcgcg aggtgggcgg gatcactcca cccgggcccg tccgcggctt
    11221 gctctccgct caaggtcgct tctgtactct ggggtgatgc gacgcctgcg cccggaccgg
    11281 cccccgaccg tcagagaact gctggcctcg ggccggtcct tctccttcga gttcttcccg
    11341 cccaagaccg acaagggcgc ccggaacctg tggcggacga tccgcgagct ggagcccctc
    11401 cgcccgtcgt tcgtctcggt gacctacggc gcgggcggcg gcacgcggga caagaccgtc
    11461 gacatcgtcg agcggatcgc gaccgacacc acgctcaccc ccgtcgcgca cttcaccgcc
    11521 gtcgaccact cgcaggccga gctgcgccag ctgatcggcc ggttcgccgc cgtcggcgtg
    11581 cgcaacatcc tcgccgtgcg cggcgacccg cccggcgacc cgatgggcga gtggatcaag
    11641 caccccgacg gcgtcgagta cgccgccgac ctcgtccgga tgatccgctc ctacggcgac
    11701 ttcagcgtcg gcgtcgccgc gttcccctac aagcacccgc gctcgcccga catcgagagc
    11761 gacacccggc acttcgtcgc caagtgccgc gccggggccg actacgcgat cacgcagatg
    11821 ttcttccgcg cggaggactt cctgcgcctg cgcgaccgcg tcgacgccgc cggatgcgac
    11881 gtcccaatca tcccgggcat catgccggtc acccagctca gcacgatcga gcggtccgag
    11941 cagctctcgg gggcaccgtt ccccgaggac gtgcgcgccc ggttcgaggc cgtcggcgac
    12001 gacccggagg ccgtccggcg cctcggcatc gagcacgcgg cggagctgtg ccgcgacctg
    12061 ctcgaccagg gcgtgcccgg catccacttc atcaccttca acaagtcgac ggcgacgcgc
    12121 gaggtctacg gcctgctgga ggccgacggg tacggcgcca ggggcagcgt cccgcccatg
    12181 acggcataga gcggcccgcc gccggggaac tcgaaccccg tcagcagatc gaccattccc
    12241 accgaccgat acaggcgccg ggcgggggtt tcggagcgca ggtccagcgt ggacagcacc
    12301 accgtccgct ccggccggcc ctcgcacaac gcggtcagca gcccccgccc gaggccccgg
    12361 ccctgcgccg ccgggtggac gtgcagctcc gccacctcca gcgggtcgtc catccaggcg
    12421 tcggcgtgct cggggccctc ccgcgcggcg agcgcctggt ggacgacgtc gtgccaccac
    12481 tgcccgtgcg cgccgtggaa cccgtacgcg aaccccagca ccggcccggc caggccgggc
    12541 agcggcccgc gccgctccgc gacgaacgcg cggaaaccgg ggtaggccgc gtgccgctcc
    12601 atgatcgtgt ggcggcccgg gagctgctcg tgcggcggcg tcatcgcggc ggcgtagacg
    12661 tccagcatcg ggccgagccg gcgcaggaag gcgcgctcgt cgatctcgcg cagcttcgga
    12721 tccctcaccg gacgtccctc accacacaga gactagacgt cccgcccgat cacccgcgcc
    12781 ggaacgatga tccgcagtgg tcacgggcgt ggcggggacg ccgcgcgccc ggcgggcctc
    12841 agaccttggc gatggtgcgc tgggtcgcgt tgagccggtc gtagatgtcc cagaggatgc
    12901 ggtcggcggc cttgcgcagc gcgttccggt tggcgtcgag ctgcccgccc cactggcgcg
    12961 cctccgggcc gagccaggcg tccgtcgagt tgaacgtgcg ggcggacgcg tcgagcgcgt
    13021 tcctgagccg gtcgatgctg ccgtaggcgt ccgcgtacgc ctggtacagc cgcgcgtact
    13081 cggggttcgg acgctcggtc ggcgggaggc tcaccgccgc cgcggcctcg atcggcgggg
    13141 gcaggctccc gggcggcggc ggggcggacg aggggaggga cacggtcagc cacccgcctt
    13201 caggtgcagc ccggcgagcg cctcgcgcgt ccggtggctc aggtcggcgc cggtgagcac
    13261 ctggagcgcg accggccgca cgccctcccg gtcggcctcg gcgaggaacg cgcgcagcca
    13321 cctcgcgtcc atcgtcaggt ggtggctgga cgtgcccagc gactcccgca gggccttcaa
    13381 ccgcgccggg tcgccgtggg cggccttcac cagcgccgcc gcggacgcgg ggccgagccg
    13441 ctcgtacagc gcctcggtgt agtcggggtc gtcggcgttg gcgcgcaggt gcttccagac
    13501 gccgtccggg acggggtcgc cgtcgcggac ggcggcggcc accgccagcg cgtccgcccg
    13561 cgcggccttg gccgccgcct gccgggtcgg gaagttgccg aggtcgccgg cgccccgcga
    13621 ggtcggcggc gccgtgtgcc tcggcggccg taccggatgg cgccgctcgg gcgtgcccgg
    13681 cgcaccgggc gagggcgtgc gcggcgcggg cgcgcccggc ctgccgggct tcacgccgcc
    13741 gccggggccg gggctcccgc cggggctcgg cttcgggctc ggcgcgtgga cgggcgggac
    13801 gtcgacgccg ccgccgtccg gatgcgtgat cgcgtagttg tagcggcggg tcagcatgcc
    13861 gagctggtcg gcggcccaca tcgcgacctg gtcggcctgc cggtacccgg tcgccggcac
    13921 cccgggcggc gggcggtgcc cgttcagcca gccctggatc gcgttctgcg cgtcctggag
    13981 ctggcggatc acccggtcga gcgcgggcgg gtcgatcccc cggaactccg ggtcgcgcgc
    14041 cgccgggccg gagcgcatct gcgctgtcat cgcccctccg gttggtcacc gatcgtcatg
    14101 gctcggttcc gcggaatcac acctcggtcc ccagaatcac atcagggtca ccggctgtcg
    14161 agggcccggc gcaccgattc gtcatcacgc gccaccaccg ccaccgcgcc ggtcaggatg
    14221 atcggccgct ggatcagcac cgggtgcgcc accatgacct cgatccagcg cgcccggtcg
    14281 tgctccaggg cggcgaggcc gagctccttg gcgacgggct cgttcagccg cgcgacgtcc
    14341 cacggctccg cgccgatcct ggtcagcgcc gcgtccagct ccgccgccgt gggcggctcg
    14401 tcgaggtagc ggcgctcggt gtaggggacg cccgcctcgt ccagcgcggc cttcgcggcg
    14461 cggctcttgg agcagcgcgg gttgtgccac agttccgtgg cctcgttgtc gcccatctca
    14521 gcccacctcc gccggggtgc ccccggtgat cctcagcagt tcctcgtacg aggtggggaa
    14581 cacggtgtgc gggtgcccgc cggccgccca gacctcgtcg tacttgtcca gccagacgtc
    14641 cacgagcgta cggatcggct cggggtggcc caggggagcg acgcccccga tgggctggcc
    14701 cgtcgcctcc cggacgaact ccggcgtcgc cctgcgcacc gccgccgcgc ccaccagcgc
    14761 cgcgacccgg gccgtgtcga cccggtgcgc gccgctcgtc agcaccagca gcggcgcccc
    14821 gtcggcgtcg aagacgaggc tgttggcgat cgcgccgacc tcgcagccga gctggtcggc
    14881 ggcggcctgc gcggtccggg ccgagtcggg caactccacg atcttcccgg ccgccccctg
    14941 cgcctccagg gccttcgcga cacgttcggc gtttgcgtgc atgggaagca ctttaaggtc
    15001 agcggtgagg cgaaggagac catggcatgc ggaaaagcgc ggcattgctg atcccgatcg
    15061 tcctgctggc cggatgcaag acggcgagcg acgcggcccc cgccgacgcg ggacgctcct
    15121 cgcagggccg caaacccccg cacgaccggc ccaggcacaa gcccaagccc aagcccaagc
    15181 gggagcccgc gcacaagccg aagaccaggt ccacgcccag gccgtcgccg accaggcccc
    15241 cgctcagggc cggggaccgc aaactcaggc cgggcgccga gggggccgac gtccgcgagc
    15301 tccagcgccg cctcacgagc ctgcactacg acccgggcaa ggcggacggg gagtacggga
    15361 cgtccaccca gctcgccgtg tgggcgttcc aggcggtcaa ccggctcaag ccgaccggca
    15421 cgctgggccc ggccttctgg agggcgctgg acgaccccaa ggagccccgc cccatggcga
    15481 ggcgccacga ggccgaccgc gtcgacgtcg acctgcgccg ccagtacctc gtcctctaca
    15541 aggacggcag gccccggctc atcacgcacg tgtcatccgg ctcgggggag tactactgcg
    15601 ccaaggaccg cggcgccacc gtcgcccgct gccgctacgc catcacgggc accggcgact
    15661 tccggacggg ccgccgcgcc aagggctggg agatctcacc gctcgggcgg ctctacaacc
    15721 ccgtctactt caacggcggc atcgccttcc acggcgcctt ggacgtgccc cggtacccgg
    15781 cctcgcacgg ctgcgtccgc atgcccatgc acgtcgcgga gtacttcccg agcctggtcg
    15841 ggacgggtgt ggccgtgcac gtccgacgcc cggggtgacg gacggtcagg cgcttcgtgt
    15901 aacccgctga cctgtgggaa gcaccacccg ttcgaacacg ttgacgaatc gctccggggg
    15961 cgctttactg tgagtgcgtc gaacttatgt tcgacgtggt gcgggactcg cggcccgcgc
    16021 cagggcgacg tccccgcccg gtggcagcgc gatgcccccg ggcgggacgg acggccgggc
    16081 ggagtgaggg gaagctctcc gcccggccgg cccgagcccc ggaaggaggc agtcatgtcc
    16141 ggaacgacga ccgcccgcgg agtccactcc gccgcccagt tcggcccgcc ggccccgcgc
    16201 tcgcggccga tgcccgcacc gcgcccggcc cacacggccg tcggccagct gcacgctgcc
    16261 cgcatgggcc tcgccgaggc ggccgaggcc acctcgcccg ccgtccgcta cgtctgcgcc
    16321 cacctggccg cgctgcgcgc cgccgcagcc gtgctggcgt ccaaggaacc gttggagacg
    16381 caccgcaggg ggcgtccccg cagcgtgtgg gtcctgctgc ccgaggccga gcccgcgctg
    16441 cgcgagtggg ccgcgttctt cgccgccggc gccgacaagc gcgccgccgc cgaggcgggc
    16501 ctgccgcgcg ccgtgacccc gcgcgaggcc gaggagctgc tgcacgacgc cgaggtcttc
    16561 gtcaccctcg tcgaggacac cctcggcgtg accagccagc ccaccctgcc catccccgag
    16621 gcgagctgac cccgaccccg ccccccgcca accccgccaa cccgccgagt acctcccggg
    16681 ccactcccgg gccgtcccgt cgacctcccc aggggacggc cgcgcccgaa ggccggggcc
    16741 gccgctggag cacggccccg gccttcgcca cgcccgacct cgcggtgccc tagaggcggg
    16801 acgcctcctt cagcgggcgc caggccgccg cggtgaccag ggccgtgagc gcgcctgcga
    16861 tccagtaggg cgcggtgacg ccgcccgcgc gggccaggac gccgccggtc agcaggccga
    16921 gcgccgcgcc gctggagtcg gccagcgcgt agacgccgcc aacccggccg agcagccggt
    16981 ccggcgtagc ccgctgccgg acggtcgtgg cgatcacccc ccacaccatc gtgtggacgc
    17041 cgaacgccac gaggatcgcg gcggcgaccc aggcgtgccg tgtcgaagcg agcaccaggt
    17101 gcgtcgcggc ctccagcgcc agccctgcgc gtagcagggc cgtggcgccg aaccggcgct
    17161 ggagccggtc ggcgaggacg gtcccggcga ggccgccgaa cccgaacgtg gtgagcagga
    17221 gcccgtaccc gacctccgac agcccgaggc ggtcggcggc gtacaggacg aacaccgaga
    17281 acgcggagca gaacgcgatg ttcgccacgc ccatcgacag cgcgagcgtg cgcagcagcc
    17341 ggtgcgacca cagccagcgg acgccctcgg cgatgtcggc gcgcagcgag cgccggtcgc
    17401 cgggcgggcg gcctcgggtc tctgcgggca cccgccgcat ggacgcgacc agcagggccg
    17461 ccaccacgaa cgtgacggcg tcgaagccga acgggaacgc cgcgccagcc gcgaacagcc
    17521 aggcgccgag cggcttggcg gcgagctggt tcccgaccgt gaacgtggcc atcagccgcg
    17581 cgttggcggc ggcgagccgc tcgggcggga cgatcgcggg gagccgggcg acggcggcgg
    17641 tgtcggcgac cgtctcaccg agcccgacca ggaagaacac cgcgcacagc agcgggacgg
    17701 tcgccgcgcc ggccgcgacc agcagggcca gcccggcgag cacggcgccg cgcagcaggt
    17761 cgaccgcgca gatcagccgc cgccggtcga cccggtcgac gaccgcgccg ctgaccagcg
    17821 agaacagggg ccaggggagg gcctgcgcga acgcgacgag ggcgacctgc gccgggtcgc
    17881 gggtcaggga cgcggcgagc agcggcccgg cgacgacggt gacgccgtcg ccgacgttgg
    17941 agacggccga ggccgtccag agcttggcga actccgcgcc gggacgcgcg gacatggggg
    18001 cacgcaaaac agagctcctg ggagatcgag gcggtcatgc cgatgaccgc ccgcgctccg
    18061 ggagtcgcgc ccccgcgcgc cggagaccgg cgcggcggag cgaagggtgg ctcagggggc
    18121 ggcgggctcc cgtggcgggg cgtcggtcct tgcccttgcg cgagccatgc gtgctccttc
    18181 gcgtcggtgc ggcgtccgtg ccgcgtccgt ctggcgcggc gtccgtgcgg cgccgtctgg
    18241 cgtcggcccg aatgtaggcg gacggcgccg cccgcctcaa cgggattccg ggccgggacg
    18301 cgaaacgggg gcccggtgtc ggccgggccc ccgtctcggt gctgccaggg gttagatggt
    18361 gctaggggtt agaacgactc gacggcgcgc cgcgcctccg ggtcgaggac gccccaggtg
    18421 atgagctcct cggtgagctc gttcggggac ttgtcgtaga tgaccgcgag tgaacgcagg
    18481 tcttcctggc ggatggacaa aacctttccg ttgtagtcgc cccgctggct ctggatcgtc
    18541 gcggcgtaac gggcgagagg accggccttg tctttcggaa gctgctgcaa ccgctcgagg
    18601 tcgatcacga gcttgggtgt aggcccgagc gggctcggcg cggctccgcc gggcagcaac
    18661 tcggaaaccg gcacgccgta gaaatcggcg agctcggcca gcttctgaac ggtgacggcg
    18721 cggtcgcccc gctcgtacga acccacgacg acggccttcc agcggccgcg ggacttctcc
    18781 tccacaccgt gcagggacag gccctgctgt gtgcggatgg cgcgcaggcg cgcgccgaga
    18841 gccttagcgt attcagacgg cattgtcggc cccccaggct cactttcgtc gtcgtatgcc
    18901 cccggcgggt cgcctggggc ggaggcgggg aaccccgagc gctgatcgct ccaggaatcc
    18961 acctccgggg atggttacgg acagtgacgg taaaacgggg acggcctcag gtcaagctga
    19021 ttggaaaaaa gcggtcgaat cagtaggtct cgctgggggt ccccccgatc gcccggaagc
    19081 ccggccgcgt cggcgtcgcg ggcgccgcgc cggcccgccg gaccgttccg agcctgttcg
    19141 agtgtgaccc ctctcaccag gcaagacgtg gaccggtccg gtgcgggtcc gcggtagccg
    19201 actgctacgg tgtgggggac aaggcgtcct ttaagacccg tcctgtgagg cgggaaagga
    19261 ggtttcggtg gtgaatgctg cctcccggcc ggaagagtcg gcggcggcgc gcgtggcgga
    19321 cggtgacccc cggcccaagg ccgttctgga gggaccggac atccggcgcg cgctgacccg
    19381 gatcgcgcac gagatcctcg aacgcaccaa gggcgggcac gacgtcctgc tcctcggcat
    19441 ccagacccgc ggggtgacgc tggccgaacg gctggccgcc ctcctcgggg acgtggaggg
    19501 ccgtccggtg ccctgggggt ccctggacgt gacgatgtac cgggacgatc tccggatgcg
    19561 tcccgcgcgc gctctgggcc gcacagaggt gccccaggac ggcgtcgacg accgcgtggt
    19621 cgtcctcgtc gacgacgtgc tgttctcggg ccggacggtg cgcgccgcgc tggacgcgct
    19681 gaacgacctc gggcggcccc gcgccgtcca gctcgcggtg ctggtcgacc gcgggcaccg
    19741 acaactgccg atccgcgcgg actacgtcgg caagaacctg cccacgtcga tgcgggagac
    19801 cgtgcgggtc ctgctgggcg agaacgacgg acgcgacgcg gtgctgctcg gtccggcggg
    19861 gggtgaccgg tgaagcgcca tctgatctcg gcggccgacc tgacgcgcga tgacgcgctg
    19921 ctcgtcctcg acacggccgc ggagctggag aaggtcgcgg gccgctcgat caagaagctg
    19981 ccgacgctgc gcggccggac ggtcgtcaac ctgttcttcg aggactccac ccgcacccgg
    20041 atctccttcg aggcggccgc caagcggctg tccgccgatg tgatcaactt ctccgcgaag
    20101 gggtcgagcg tgtccaaggg cgagagcctg aaggacaccg cgctgacgct ggaggcgatg
    20161 ggcgccgacg gcgtcgtcgt ccggcacggc gcctccggtg ctccgcaccg gctcgcgggc
    20221 tgggtgcagg gcagcgtggt caacgccggg gacggcaccc acgagcaccc gacgcaggcc
    20281 ctgctggacg cgttcacgat gcgcaagcgg ctcggcgacc tggagggccg ccgggtcacg
    20341 atcgtcggcg acgtcctgca cagtcgggtg gcacgctcca acgtgctgct gctcgggacg
    20401 ctcggcgccg acgtgaccgt ggtcgcgccg cccacgctgc tgccggtcgc gatcaacacc
    20461 tggccgtgcc aggtgtccta cgacctggac gcggtgctcc ccaagagcga cgtgatcatg
    20521 atgctgcgcg tccagcagga gcggatgaac gccgcctact tcccgaccgt ccgcgagtac
    20581 agccggcggt acgggctgga cggcgagcgc atggccgcgc tccccgacca cgccatcgtc
    20641 atgcatccgg ggccgatgaa ccgcggcgtg gagatcgccg ccgaggtcgc cgactccgtc
    20701 cggtccacga tcgtcgagca ggtcgccaac ggcgtcagcg cccgcatggc cgtgctctac
    20761 ctgctgctcg ggggctccga gcccgccatc ggcacggagg tcgccgaatg aaccacctga
    20821 tcaggggcgc ccgcatcctg ggcggcgcgc ccgccgacat cctcgtccgg gacggccaga
    20881 tcgccgagat cggctccggg ctcgacgccg gcggcgccgc ggtcgtcgac gccgacggcc
    20941 tggtcgcgct gcccgggctc gtggacctgc acacccacct gcgcgagccg ggacgcgagg
    21001 acgccgagac cgtcgagtcc ggcacgaagg ccgccgcgat gggcgggttc acctccgtcc
    21061 acgcgatggc caacaccgac ccggtc
//
