LOCUS       NZ_JALDPQ010000041     22871 bp    DNA     linear   CON 28-MAY-2024
DEFINITION  Streptomyces sp. TRM75563 677, whole genome shotgun sequence.
ACCESSION   NZ_JALDPQ010000041
VERSION     NZ_JALDPQ010000041.1
KEYWORDS    WGS; RefSeq.
SOURCE      Streptomyces sp. TRM75563
  ORGANISM  Streptomyces sp. TRM75563
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1  (bases 1 to 80469)
  AUTHORS   Chen,Y.
  TITLE     Streptomyces aheensis sp. nov., isolated from road
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 80469)
  AUTHORS   Chen,Y.
  TITLE     Direct Submission
  JOURNAL   Submitted (22-MAR-2022) College of Life Science, Tarim University,
            Hongqiao, Alar 843300, China
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: 14-MAR-2022
            Assembly Method                   :: ABySS v. V2.5
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 400.0x
            Sequencing Technology             :: Illumina NovaSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_022748615.1-RS_2024_05_28
            Annotation Date                   :: 05/28/2024 05:18:04
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 7,476
            CDSs (total)                      :: 7,413
            Genes (coding)                    :: 7,165
            CDSs (with protein)               :: 7,165
            Genes (RNA)                       :: 63
            rRNAs                             :: 2, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 56
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 249
            CDSs (without protein)            :: 248
            Pseudo Genes (ambiguous residues) :: 1 of 249
            Pseudo Genes (frameshifted)       :: 108 of 249
            Pseudo Genes (incomplete)         :: 202 of 249
            Pseudo Genes (internal stop)      :: 19 of 249
            Pseudo Genes (multiple problems)  :: 75 of 249
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 19:22:52
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 51077
            Orig. end                         :: 73948
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            JALDPQ010000041.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..22871
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="lanthipeptide-class-iv"
                     /region_number="1"
                     /rules="(cds(LANC_like and Pkinase) and not micKC)"
                     /tool="antismash"
     cand_cluster    1..22871
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(cds(LANC_like and Pkinase) and not
                     micKC)"
                     /kind="single"
                     /product="lanthipeptide-class-iv"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..22871
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="True"
                     /core_location="[10000:12871](-)"
                     /cutoff="20000"
                     /detection_rule="(cds(LANC_like and Pkinase) and not
                     micKC)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-iv"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..12871)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(cds(LANC_like and Pkinase) and not
                     micKC)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-iv"
                     /protocluster_number="1"
     gene            complement(287..526)
                     /locus_tag="MQC87_RS04365"
                     /old_locus_tag="MQC87_04365"
     CDS             complement(287..526)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015610436.1"
                     /locus_tag="MQC87_RS04365"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MQC87_04365"
                     /product="DUF397 domain-containing protein"
                     /protein_id="WP_242736649.1"
                     /transl_table=11
                     /translation="MSTDLHWFKSSYSGSEGGDCVEVALTWSKSTYSGDQGGNCVEVAA
                     CPHTIHIRDSKDLTVPPLAVSPTTWTSFVDFAAS"
     gene            complement(523..1338)
                     /locus_tag="MQC87_RS04370"
                     /old_locus_tag="MQC87_04370"
     CDS             complement(523..1338)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018510895.1"
                     /locus_tag="MQC87_RS04370"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MQC87_04370"
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="WP_242736651.1"
                     /transl_table=11
                     /translation="MHSSDQPESAAEMFGLLLRHFRERAGLSQEQLGKRIGYSKSQVAM
                     VERGARPPKGVFVQRADEVLGAQGALIVAAPKPRKGSPLPDWFTPFAEEETGAFARHEY
                     ETHVMPGLLQTEAYARAVFASAHPTYDDDEIEEKVAARLARQTLLGRKPLPDISFVLEL
                     SALTRPIGSRRILKAQLHHLAEVARLRHVRIQLMSPDREDHAGLNGPFVLLETAERRQL
                     AYIEGQGGSFFITEQPDLGNLFGRYGVLRAQAYTPERTLEAIEKMAEEL"
     misc_feature    1378..1393
                     /note="TFBS match to CRP, Cyclic AMP receptor protein,
                     confidence: strong, score: 18.39"
                     /tool="antismash"
     gene            1421..1846
                     /locus_tag="MQC87_RS04375"
                     /old_locus_tag="MQC87_04375"
     CDS             1421..1846
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018958696.1"
                     /locus_tag="MQC87_RS04375"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MQC87_04375"
                     /product="hypothetical protein"
                     /protein_id="WP_242736654.1"
                     /transl_table=11
                     /translation="MELKNSPDPVPSWIPASGHALRHVGIHFDAVRAIGLLGEEIAYEV
                     MQFTDFQAGPIVRSGIGERSMYFLLAPGAAAEYRWPPGVEAMSRSARGDAFVGVPALGG
                     GTWPLDWRSRPTVQDPFVDGGLLHEMAWLRAGCVVKE"
     gene            1966..2193
                     /locus_tag="MQC87_RS04380"
                     /old_locus_tag="MQC87_04380"
     CDS             1966..2193
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007454334.1"
                     /locus_tag="MQC87_RS04380"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MQC87_04380"
                     /product="hypothetical protein"
                     /protein_id="WP_242736657.1"
                     /transl_table=11
                     /translation="MQALNWSGVLVASPVLLIAGAPIRRRYLRHIYRDGAPPLLDKERG
                     HVSAHYYVANHPLLAWLCLPTEALARRFQD"
     gene            complement(2345..2767)
                     /locus_tag="MQC87_RS04385"
                     /old_locus_tag="MQC87_04385"
     CDS             complement(2345..2767)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="MQC87_RS04385"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="MQC87_04385"
                     /product="hypothetical protein"
                     /protein_id="WP_242736661.1"
                     /transl_table=11
                     /translation="MRTTAMRLTAVAGGLVMAAGALTVGTASTAAAATCYGGAAGKTFN
                     MGTDQAEHRFGPYTTTSRCNDINLKITTWGNASPLVVRVCFHPSSGGTTCNSWKEFYKS
                     SDLNKWRVIASDVKNGTRYSVSMDLASNTFKGDLAH"
     misc_feature    2764..2782
                     /note="TFBS match to DmdR1, Iron(II)-dependent repressor,
                     confidence: weak, score: 21.87"
                     /tool="antismash"
     gene            complement(3084..3314)
                     /locus_tag="MQC87_RS04390"
                     /old_locus_tag="MQC87_04390"
     CDS             complement(3084..3314)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="MQC87_RS04390"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="MQC87_04390"
                     /product="hypothetical protein"
                     /protein_id="WP_242736731.1"
                     /transl_table=11
                     /translation="MPARTWNASGLTTSTGYAGRAAGTSSYKTVKKVKSTSTGALKTTV
                     KAGKSGTWRWTYFGNTTSGAKSSTGDRVEVR"
     gene            complement(3366..4151)
                     /locus_tag="MQC87_RS04395"
                     /old_locus_tag="MQC87_04395"
     CDS             complement(3366..4151)
                     /EC_number="2.1.1.-"
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1292: hypothetical
                     protein"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006126602.1"
                     /locus_tag="MQC87_RS04395"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MQC87_04395"
                     /product="SAM-dependent methyltransferase"
                     /protein_id="WP_242736664.1"
                     /transl_table=11
                     /translation="MTAQAPHPPIDTSKPHSARVYDALLGGKDNYPVDQEVAELLPVEA
                     KIGAHQQRAFMNRATAWLAGQGVTQFLDIGTGIPTAPNLHQVAQEIRPSARVVYCDNDP
                     IVLRHAEALLISRPEGVTDYVHADVREPAIILDAARETLDFDRPIALSLLGLLHFLPDA
                     EDPIGIIRTFTDAMTPGSYVVLSHGASDVNAEVGQQSEDEYKKGGIQLALRSRKEFERF
                     FEGLEIAAPGLVMAPEWFNGTPAPVQEHSGIYVAVARVP"
     misc_feature    4169..4184
                     /note="TFBS match to DasR, N-acetylglucosamine dependent
                     repressor, confidence: weak, score: 20.7"
                     /tool="antismash"
     misc_feature    complement(4176..4191)
                     /note="TFBS match to RutR, Regulator of the pyrimidine and
                     purine metabolism, confidence: weak, score: 20.18"
                     /tool="antismash"
     gene            complement(4209..5972)
                     /locus_tag="MQC87_RS04400"
                     /old_locus_tag="MQC87_04400"
     CDS             complement(4209..5972)
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1288: ABC
                     transporter related protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020551013.1"
                     /locus_tag="MQC87_RS04400"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MQC87_04400"
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_242736666.1"
                     /transl_table=11
                     /translation="MSEAAPRPIDRHLFAGFLRQHRGAAVAVAGWSLLEAVPALASGLL
                     VAAALDRGFLAGRPAEGFFWIGLLGAAMVFRALMTRTLTPWLGRIVEPLRDDLVTAVAA
                     GAVQRAAAGARDTAGAGVARLTVQVETVRSLVSALLRSARQLGVSLLMAFVGLAALSAP
                     VAAVTLPPVLLTLLLCVPRLRVLARRQRRQLRAEERLTGVAGETFDGIRDVVACGARDR
                     VADDLSARITDHRDAVRAVARTASANTLLVSLGSHLPLLVLLLSAPRLLDSGALSVGEL
                     LGATSYLVSGVAPALRSLVTVLGSWGVQLVTVLSQLSRSTREARPGPPGGPGPTLPPRT
                     PRTPRSPDLSLVNVVYAYGPGAAPVIDGLSLDIPAGSHLTVVGPSGAGKSTLTTLLAGM
                     AGPDSGRLTLGGVPATEVDRAWLHRAVTLIPQEAYVFTGTVRDNLRYLHPQARDADLLA
                     SATAVGARTLVDRLGGLDAPVGLDGPPLSSGERQLVALARAHVSPASIVLLDEACCHLD
                     PAAEERAERAFADRGTTLVVVAHRISSALRAPRVLVLDGDRTAVGTPAQLLDSSPLYAD
                     LVGHWVSAGAP"
     gene            complement(5969..7756)
                     /locus_tag="MQC87_RS04405"
                     /old_locus_tag="MQC87_04405"
     CDS             complement(5969..7756)
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1288: ABC
                     transporter related protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: protein motif:HMM:NF012869.4"
                     /locus_tag="MQC87_RS04405"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MQC87_04405"
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_242736669.1"
                     /transl_table=11
                     /translation="MTSPRRLVWDATARTRGWFVLASATAVLGSAGTLAFPWAMARALD
                     AVVARRSVTGPVLVCAALLALVVTAGSLQTLANGGYGSGTVAALRRTLARRALDAGVPG
                     TADFPAGDLAGRLSAGCAQAGSAGVTLVTASTAVLTSLGGVVALWLLDWRIGLCFSLGV
                     PPLALIARMFMNRGSGLFLRYQETQGRISALLLEALGGARTIGASGTAAAETRRVLDPL
                     PELSRTGHRVWALQRDTGWQVGLLIPAVEVLVLCAGGLALLHGDISAGELAAVVGYTAL
                     AMAALDQLDALFALGMSAAGARRVAEVVDQPVPAPGTRARPAGRPGTVTLSGVTVRSGA
                     RTVLDAVDLVVPAGTALAVVGRSGAGKSTLAALIGRLREPDAGLVAIDGVPLRELTPQA
                     LRAAVGYAFERPALLGTTVAGMIAFARPDASREEVTAAAAAARADDFIARLPRGYDTPL
                     TEAPLSGGEVQRLGLARALVHDPAVVVLDDALSSLDTATEARVGSALASAWSGRTRVLI
                     AHRVSTAARADLVAWLEDGRVRALGPHADLWQLDDYRALFAASTGPETVPDRDTGSGAE
                     AWTDRNTPPHPNPHAQEPV"
     assembly_gap    7857..7873
                     /estimated_length=17
                     /gap_type="within scaffold"
                     /linkage_evidence="paired-ends"
     gene            complement(7888..8019)
                     /locus_tag="MQC87_RS04410"
                     /old_locus_tag="MQC87_04410"
     CDS             complement(7888..8019)
                     /codon_start=1
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF038157.1"
                     /locus_tag="MQC87_RS04410"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MQC87_04410"
                     /product="ALQxL family class IV lanthipeptide"
                     /protein_id="WP_189460106.1"
                     /transl_table=11
                     /translation="MIDNTMTVDVDELQTLEGEESVALAGCTRTCTWTCSITSIEQQ"
     CDS_motif       complement(7942..8019)
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence: MIDNTMTVDVDELQTLEGEESVALAG"
                     /locus_tag="MQC87_RS04410_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       complement(7888..7941)
                     /prepeptide="core"
                     /locus_tag="MQC87_RS04410_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class III"
                     /score="2.70"
                     /molecular_weight="1835.1"
                     /monoisotopic_mass="1833.8"
                     /core_sequence="CTRTCTWTCSITSIEQQ"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MIDNTMTVDVDELQTLEGEESVALAG"
                     /leader_location="[7941:8019](-)"
                     /alternative_weights="1853.1"
                     /alternative_weights="1871.1"
                     /alternative_weights="1889.1"
                     /alternative_weights="1907.1"
     gene            complement(8016..10004)
                     /locus_tag="MQC87_RS04415"
                     /old_locus_tag="MQC87_04415"
     CDS             complement(8016..10004)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF00561"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_S9"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF012546.4"
                     /locus_tag="MQC87_RS04415"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MQC87_04415"
                     /product="alpha/beta fold hydrolase"
                     /protein_id="WP_242736672.1"
                     /sec_met_domain="PF00561 (E-value: 3.6e-07, bitscore: 22.3,
                     seeds: 48, tool: rule-based-clusters)"
                     /sec_met_domain="Peptidase_S9 (E-value: 6.8e-23, bitscore:
                     73.5, seeds: 64, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNRRPERISFRFSARSRFAACLVATADGALAPGWWDLDGTHPPYP
                     GDTPRYREGAPAETTATQVLPTEDGGLLRLRGTAGSGRHLLLLSRPAPASATAAGTSLA
                     EPQVPYPAGPELKDPSPAEDLVVEARGLRLVPGGPPGTLALAVETSHDGRTRVRRVRST
                     PLRLSDPVILPGRVTALLPLDGTGCRYATDLEGPDGYRPVSLDLRDGKWHALPSPANGR
                     IHRLLLSAPASGLLLTASDPGDGRLRIAHAALGDRARLSFPDRLNSLDGAVLPLAADPA
                     GERVALRVSRGAQARLFLYDVGADRSRPAALPPGAFHPVAGWSTSGLRVVYATPDRPAD
                     LVTVPDTASYDAPSDTREAPARTPDAPRAPHAATEWFATPSGRFEAVVLGDRRTAPTVV
                     VALHGGPEDHWTLGHDPVLARLSEAGAAVVAPNQRGSTGYGRAHAEAIHGAWGVPDLAD
                     IRSLVRTLTEQRPPDAEPPVLLGISYGGFLALLAVCADPYAWARCAVIAPFLSARGLRE
                     RSSPAVRALVDRHGLGEPPDDDLGARDVEGLAHRIRVPLLALHGCDDPVVPVDETRRLH
                     RSLAKAGGPERAPHDCLDIAGAGHHPLQERGGAELTDRLVSFLTARVPDRRRTLVPPEL
                     TVADAAVRHRRSSAVFGHITHDERTPP"
     gene            complement(10001..12871)
                     /gene="lanL"
                     /locus_tag="MQC87_RS04420"
                     /old_locus_tag="MQC87_04420"
     CDS             complement(10001..12871)
                     /codon_start=1
                     /gene="lanL"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-iv: Pkinase"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-iv: LANC_like"
                     /gene_functions="regulatory (smcogs) SMCOG1030:
                     serine/threonine protein kinase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF038150.1"
                     /locus_tag="MQC87_RS04420"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MQC87_04420"
                     /product="class IV lanthionine synthetase LanL"
                     /protein_id="WP_242736675.1"
                     /sec_met_domain="Pkinase (E-value: 8.8e-16, bitscore: 50.3,
                     seeds: 54, tool: rule-based-clusters)"
                     /sec_met_domain="LANC_like (E-value: 8.8e-44, bitscore:
                     142.0, seeds: 47, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSTDRDEHDGGSFFALDTGLLPGIVEGVLHRRGATQWAVEQGEFW
                     CSVRPRGHRSGEQGWKLHLSATPLSAALVLAVAADVLVEERASFKFAGALDRVALLTGG
                     RADRGGGGKFITVYPDDPELFRRLARRLHAATLGLRGPRILSDRPYAPGSLVHYRYGVF
                     GGVRTTTNDGDTDVRLRNPGGGLEKDRRQAWVTTPAWAPPPFPEPAASPETAPSPEAAP
                     SPSREPAGPQKPTRTPGRKSVRLNGRYVVAKAIRHAFKGGVYLATDETTGRQVVVKEAR
                     AHVGVRMDGTDLQDTLRHEAEMLEALDPLGFTPAAIELFAQGGNLFLAQEFVPGQTLRD
                     RLVERPVRNLAEFLALGRQIVDIVAAVHGTGRVLRDLSPNNLMVTPEGRVRLIDVEYLA
                     PEGVPVRRGYTPGYVGPEVSSLRDYDFTAPTYAGDLYGLGAVLLHLATGVDMLLVPDDR
                     PMGDRTQALITPAIADHPWAAPLLPLLLALCAPLPEERWGLPRIRKALAELPGTGHRST
                     GGETGGARVTGTGATGGSGVPALSGEERERLIADGIAYLLRTGPGSGGHLWDVSAFGAT
                     TDPLNVQYGSAGVLAVLTRAAAAGAGPDVRDGVAELTEWTRRRLADLPTGRTPDGTLLP
                     GLHFGRSGTAWALLDAALLLGDEDVAAEASALARAVPLDWPNRDICHGAAGAGMTQLHF
                     WRTTGDPVFRDRAVACAQAIISAAEDHPAGVIWPVPAAFDSNLAGARHYGFAHGIAGIG
                     AFLLAAGVAAEHEGLLWAAGRAGDTLVKLARFEAGRAVWPAGDRDADGPVGQTHWCSGS
                     SGIGTFLVRLWARTGDERHREAAVRAAAGVREAMWLSSPAACHGLAGNAEFLLDMSAAL
                     GDPRYRDQAGELATCIHTRAVRRDGLLVVPDESLEAVTGGYQTGVAGTVGMLLRLRDGG
                     PRLWMPDTPELFAPAGRHPRTAVGVR"
     misc_feature    complement(13081..13095)
                     /note="TFBS match to MexT, Global virulence regulator,
                     confidence: weak, score: 16.4"
                     /tool="antismash"
     misc_feature    complement(13198..13212)
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: weak, score: 17.18"
                     /tool="antismash"
     gene            13206..14372
                     /locus_tag="MQC87_RS04425"
                     /old_locus_tag="MQC87_04425"
     CDS             13206..14372
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="MQC87_RS04425"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="MQC87_04425"
                     /product="hypothetical protein"
                     /protein_id="WP_242736678.1"
                     /transl_table=11
                     /translation="MVIATALYRGSHLVAGGVVVAQHQRDRLFPWLALSAAIASTALIW
                     FMAARHRRLVPWVVGLDVLVIGCLLPFGAYAWGGARTQESVAWVMLLGGSASAMAAVAF
                     GARLLAVAVALLVATHLAGYLMVEADAAVTGAHLNALVFSAVVSWVLTWYLCRQGEQVD
                     SANRRALAAEAQRARFAERVAHHNALHDTVLATLTAIARGGVDANTSMMRERCAREAAY
                     LRRLVEQADDREPASEVRAALEESVRAAEALGLRVTARYHEPPAVPGEIALAMARATTE
                     ALNNVRCHAGTGHAFLTAVGDSGRLVVTVVDRGRGFATGSAGPDDAGGVAGPRASGGSE
                     GPAGPAGQAAGGIGLDRSVYARMRGVGGRAFVDSAPGEGVRVELRWPG"
     gene            14360..14992
                     /locus_tag="MQC87_RS04430"
                     /old_locus_tag="MQC87_04430"
     CDS             14360..14992
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1016: LuxR family
                     DNA-binding response regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010061151.1"
                     /locus_tag="MQC87_RS04430"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MQC87_04430"
                     /product="response regulator transcription factor"
                     /protein_id="WP_242736680.1"
                     /transl_table=11
                     /translation="MAGVITVAVVDDDRMLRDGIRSWFAGVEELDLVACAATVDELLAG
                     PWEPPDVVLLDLMLRDDRPPADNIRRLRAAGSRVLMISVVADRDRIVAAITDGADGFLT
                     KDHELSVLVEAVGEIAAGRTTHSPELAFALAYDRGSTRPRLSPQEREVLVGYASGLTLK
                     ATARRAGITVNTAKYYLDRVKAKYQETGRPTYTKIDLATRVREDGWR"
     gene            15233..16135
                     /locus_tag="MQC87_RS04435"
                     /old_locus_tag="MQC87_04435"
     CDS             15233..16135
                     /GO_function="GO:0004222 - metalloendopeptidase activity
                     [Evidence IEA]"
                     /GO_process="GO:0071586 - CAAX-box protein processing
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Abi"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003967252.1"
                     /locus_tag="MQC87_RS04435"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MQC87_04435"
                     /product="type II CAAX endopeptidase family protein"
                     /protein_id="WP_242736729.1"
                     /sec_met_domain="Abi (E-value: 2.2e-17, bitscore: 55.6,
                     seeds: 823, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRAPAGSRYDEQGRNGQGGRFGWLGELAVVVALVVVGVLVVSIAG
                     FVVAELLDAGPDSADSELFFEDPVADLVVQLLGLAIGIPIVLLAVRLLGRRPAGTVSSV
                     VGRIRWGWLLRCAAVAFPLMIVQIGLLIAWTWNDEPLGETGTGFPGWPVFLLSLAVVLA
                     LVPFQAAAEEYVFRGWLVQVIGRAVRTPWPAIVIASLLFALAHGFGELSGFLLLLYSAL
                     WWGWLVIRTGGLEAVIVMHVTNNLLAFGLAAGFGELASTETAADAPWQAMVIELVFAPL
                     YCLTMARIADRRGVERVSP"
     gene            16269..16607
                     /locus_tag="MQC87_RS04440"
                     /old_locus_tag="MQC87_04440"
     CDS             16269..16607
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006126611.1"
                     /locus_tag="MQC87_RS04440"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MQC87_04440"
                     /product="hypothetical protein"
                     /protein_id="WP_242736683.1"
                     /transl_table=11
                     /translation="MERTRLWKSFVPVVVNLMLGIPAVVPVFLIWYVLSNGPLAELGWT
                     QREPTENDGMLPWLILVVPVVAGFGGLWTLINLWMRRRLIAAASPYPYWSVSVTLTVAP
                     FLLGVAFG"
     gene            complement(17022..17621)
                     /locus_tag="MQC87_RS04445"
                     /old_locus_tag="MQC87_04445"
     CDS             complement(17022..17621)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1057: TetR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018958676.1"
                     /locus_tag="MQC87_RS04445"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MQC87_04445"
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="WP_103512052.1"
                     /transl_table=11
                     /translation="MTPETRRGYAKGRAKRTEILDQAMALFGEAGYRGASLRVIATRCG
                     ISHPGLLHHFPTKEALLLAVLQRRDDVDDEWLSLGVTRGIDHLRRLTDLAELNAKRRGI
                     VELFSVVAAEATAPDHPAHAYFEARYRTSVANTERAYLQARQAGELRDDVDPSAAAQQL
                     IALMDGLQIQWLISDCATDMAGVLRAHVRAQLTVPF"
     gene            17758..20040
                     /locus_tag="MQC87_RS04450"
                     /old_locus_tag="MQC87_04450"
     CDS             17758..20040
                     /GO_function="GO:0004553 - hydrolase activity, hydrolyzing
                     O-glycosyl compounds [Evidence IEA]"
                     /GO_process="GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007450053.1"
                     /locus_tag="MQC87_RS04450"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MQC87_04450"
                     /product="glycoside hydrolase family 3 N-terminal
                     domain-containing protein"
                     /protein_id="WP_242736688.1"
                     /transl_table=11
                     /translation="MGLKPPYLDPELPVGERVADLLGRMTLPEKVGQMLQLNAKEGVRH
                     LVEDLHAGSILHASPDRVREAAALTAKTRLRIPLLVAEDCIHGHSFWEGATIYPTQLGM
                     AATWDPELVERIARATAVEVAATGVHWTFSPVLCITRDLRWGRVSETFGEDPLLIGELA
                     SAMVRGYQGDGLDDPTAILACAKHFAGYSETQGGRDASEADISRRKLRSWFLPPFERVA
                     KEGCRTFMLGYQSMDGVPITVNNWLLNEVLRGEWGYTGTLVTDWDNVGRMVWEQKVYAD
                     YAQASAAAVRAGNDMVMTTSNFFEGAQEAVAQGELSETEIDAAVRRILTLKFELGLFEN
                     PRHPDAGRQAEFIGSAAHAELNLEAARRSLVLLTNDGTLPFAGGLEAGEEGRATGSGPR
                     TVAVIGPNADDAQTQLGDWAGSSGQADWLPDGQPRAMIRTVLDGFRDRVPADWTVSYAP
                     GARILDVGPDPEGEFFPDGQPRPEVVHPAAPDAELIAEAVAAAEAADHVVAVVGDRIEL
                     IGEGKSTATLELVGDQVALLDALAATGKPLVVVVISSKPLVLPPSALGAAAIVYAANPG
                     MLGGRAVAELLLGLVEPTGRLPLSFARHAGQQPTYYNQVRGQHGTRYADLTQRPAFAFG
                     EGLSYSTVAYTDLEVLTAVVDESESVRARVTVTNTGARPALETVQVYVSDTVTSVTWAE
                     KELKAYRQVELAPGQSREVLFELPVADCTLVDAAGRRIVEPGRFELLVGPSSRDEALLR
                     GEFTVKG"
     gene            complement(20135..20857)
                     /locus_tag="MQC87_RS04455"
                     /old_locus_tag="MQC87_04455"
     CDS             complement(20135..20857)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010071682.1"
                     /locus_tag="MQC87_RS04455"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MQC87_04455"
                     /product="hypothetical protein"
                     /protein_id="WP_242736692.1"
                     /transl_table=11
                     /translation="MRISKNLIGLAAVGILAAGCGSSSSDDSAGSSGSTGSARQAPSEE
                     AKAPEPGADLAVPVTGPQPDVLASSSDPQLKVTPKPANGASFTEKVEHKLQEDLLGRLK
                     VPGKTSANCPDGVTQKASAVSICNVTYEGATVPYEIEISEKYKPGSFLTFYNSTPKKGL
                     LVAENAYDRLWTANKNRSDISKLSCEELPAAKAVDEETETGFHCQYWGKYAGEDGKGGF
                     VKLGIKVNRHNVDFFEVR"
     misc_feature    20919..20933
                     /note="TFBS match to VqsM, Regulator of quorum-sensing
                     signalling systems, confidence: medium, score: 18.07"
                     /tool="antismash"
     gene            complement(21099..22043)
                     /locus_tag="MQC87_RS04460"
                     /old_locus_tag="MQC87_04460"
     CDS             complement(21099..22043)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018958673.1"
                     /locus_tag="MQC87_RS04460"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MQC87_04460"
                     /product="hypothetical protein"
                     /protein_id="WP_242736695.1"
                     /transl_table=11
                     /translation="MQNKRLFGLSLLLSILVLHLEAAIALVVSIVYGVTQESPNTGVGG
                     SAMFVLLLPVLAVFTTSAAAVLSLALVLPTAWLSDVLGRRFGGREVWWWVPVVAAAVSL
                     LTVGVVVVLSGEGAGPVAVVLGWCLTTAALTVPALLWRSRRERIFGPVLLWGVVAVVLT
                     AVLGGVGLATGLLREYRPPAVTSADIVGTWSDGRGGTLAFTADGRVTAVDVDEEALDVR
                     GEYDATDQESSDPQDGHNSCTGQGTWAFEPGADRWSQGVDVSFDACSYDTWNIGGTESR
                     PTLYQYIGDPDSWDLYKLTRSTGSSGSGPSVRP"
ORIGIN
        1 ggatgtcacc gaggctgcac gcccagaaga acagcccgat caccaagaag accgcgccgg
       61 tcagcagccc cagataggtg gtcgcttcca gcaggtcgac acgggcgtcg tgatcccgca
      121 cgacgaacgc ggcgacgacc acgcagaccg tggcccccac gccgtacgcc gcgccgcgcg
      181 ccatgacgct gctcaagcgc agacgcggtt cgagcacccc gtccgcgcct ctgctcatgc
      241 ggaccatgtg cgcgcccccg tcgtcaccgc accgtcgcga ctgtcgctac gacgcggcga
      301 agtctacgaa ggatgtccag gtggtggggg agacggcgag tggcgggacg gtgaggtcct
      361 tggagtcgcg gatgtggatc gtgtgggggc aggcggcgac ctctacgcag ttgccgccct
      421 ggtcgccgct gtaggtggac ttggaccagg tgagtgcgac ctctacgcag tcgccgccct
      481 cgctgccgct gtagctggac ttgaaccagt ggagatcggt gctcatagtt cctctgccat
      541 cttctcgatc gcttccaggg tcctctccgg agtgtatgcc tgggcccgca gaacgccgta
      601 cctcccgaac aggttgccaa ggtccggctg ttcggtgatg aagaagctgc cgccttgacc
      661 ttcgatgtat gccaactgcc ttcgctcggc ggtctccagc aagacgaagg gaccgttgag
      721 gcctgcgtgg tcctcccggt caggcgacat cagctgaatt cttacgtgtc gcagcctggc
      781 tacttcggcc aggtggtgca gctgagcctt gaggatgcgt cggctaccga tcggacgtgt
      841 gagtgcgctc aactccagta cgaagctgat atcggggagt ggcttgcggc ccagcagcgt
      901 ctggcgagcc agccgcgcgg ctaccttctc ctcgatctca tcgtcgtcgt aggtcgggtg
      961 ggcgctggcg aacactgccc gcgcataggc ctcggtctgg agcagccccg gcatcacgtg
     1021 ggtttcgtat tcgtgacgag cgaaggcccc tgtttcctcc tccgcgaagg gcgtgaacca
     1081 gtccggaagc gggctgccct tcctcggctt cggtgcggcg acgatcagtg caccctgtgc
     1141 acccagcacc tcgtccgccc gctgtacgaa gacgcccttc ggaggccgcg caccccgttc
     1201 caccatcgcc acttgggact tggagtagcc gatccgcttg cccaactgtt cctgcgacag
     1261 cccggcccgc tcgcggaagt gcctgagcag caggccgaac atctcggcgg cgctctcggg
     1321 ctgatcactg gagtgcacgg gctcacctcg tatgtacacc actgtccaca actcgcttgt
     1381 gaccctggtc acggtacgtg ttcggcgcaa cgctgagcgc atggaactga agaattcacc
     1441 ggatccggtg ccgtcctgga tccccgcctc cggccacgca ctccgccacg tcggcatcca
     1501 cttcgacgcc gtccgcgcca tcggtctgct cggcgaggaa atcgcttacg aggtcatgca
     1561 gttcaccgac ttccaggccg ggcccatcgt ccgctccggc atcggcgagc gcagcatgta
     1621 cttcctgctc gcgccagggg ccgccgccga gtaccgctgg cctcccgggg tggaggcgat
     1681 gagccggagc gcgcgagggg acgcgttcgt cggggtgccc gcgctgggcg gcggcacctg
     1741 gccgctggac tggcggtcgc ggcccacggt ccaggatccc ttcgtggacg gcgggttgct
     1801 gcacgagatg gcctggttgc gtgcggggtg cgtcgtgaag gagtgagtga ggcggagctt
     1861 gaccggccgg tgcgccgaaa cccgtacctt ccgccccggc ggacggatca gcacactggt
     1921 cgcatgcggt acgagacgag atccgaaaga ttcaggatca gggccgtgca ggccctgaac
     1981 tggtcgggcg ttctcgtcgc ctcccccgtg ctgctgatcg caggagcgcc gatccgccgc
     2041 cgctacctcc gccacatcta ccgcgatggg gccccgcccc tcctcgacaa ggagcgcggc
     2101 cacgtcagcg cccactacta cgtcgccaac cacccccttc tcgcgtggct ctgcctgccc
     2161 acggaggcac tcgcccgccg gttccaggac tgaacgagga gtgagctgat gtcttggggc
     2221 ccgtttgccc ctccggcctc acgtggtgtt cggaaacacg gaggaaggag tcgggcggcg
     2281 tacgagccga gccaccgttc ccggggggcg cagcctcgtg cgcctgttcc cggggtggcc
     2341 gtgttcagtg cgcgaggtcg cccttgaagg tgttgctggc gaggtccatg gagacgctgt
     2401 agcgggtgcc gttcttgacg tcgctggcaa tcacgcgcca cttgttcagg tcgctcgact
     2461 tgtagaactc cttccaggag ttgcaggtcg tgccgccgga ggacgggtgg aagcacactc
     2521 gcaccaccag cgggctggcg ttcccccagg tggtgatctt caggttgatg tcgttgcacc
     2581 gcgaggtggt ggtgtacggg ccgaagcgat gctcagcctg gtccgttccc atgttgaagg
     2641 tcttgccggc cgcgcccccg tagcaggtcg cggccgccgc ggtcgacgcg gtgccgaccg
     2701 tgagcgcgcc ggccgccatg accagcccac ccgcaaccgc cgtcagtcgc attgccgtcg
     2761 tcctcatgtt ccgctcccct tataggtccc tgtgatcgag tggcctgcgc gcagaccgca
     2821 gggggaacca ggggtcgacg accatgcgcc gtccctgcgc ggtcccccgt gggcctcctc
     2881 ggctgtgagg ccgtggacaa gctacagaac ctgcatctca cagggcccct ataactattc
     2941 agggtgttcc gctgcggggc ggttcggctg gaggagtccc acacgcgact gcggtggtcg
     3001 cagccgtgaa cgcgtggctg tgatcgacac ctccgcaacg gccctcagat cacgtcgaat
     3061 acgttgcctt cgggtcagta cacctagcgc acttcgacgc gatccccggt cgacgacttc
     3121 gcgccggatg tggtgttgcc gaagtacgtc caccgccacg ttccggactt gccggccttc
     3181 accgtggtct tgagcgcccc cgtgctggtc gacttcacct tcttgaccgt cttgtacgag
     3241 gaggtgcccg ccgcccgccc ggcgtacccg gtgctcgtcg tcaggcccga ggcgttccag
     3301 gtccgcgcgg gcaccgccgt ggccggtcgc gtgccgctct ccgtccgccc gggggacctc
     3361 cgcgcttacg ggacccgggc cacggccacg tagatgccgc tgtgctcctg gacgggcgcg
     3421 ggggtgccgt tgaaccactc cggggccatc accaggccgg gggcggcgat ctccaggccc
     3481 tcgaagaacc gctcgaactc cttgcggctc cgcagcgcca gctggatgcc gcccttcttg
     3541 tactcgtcct cgctctgctg cccgacctcc gcgttcacgt cggacgcgcc gtgggacagc
     3601 acgacgtagc tgccgggggt catggcgtcc gtgaacgtac ggatgatgcc gatcgggtcc
     3661 tcggcgtcgg ggaggaagtg gaggaggccg aggagcgaca gggcgatcgg gcggtcgaag
     3721 tccagggtct cgcgggccgc gtcgaggatg atcgcgggct cgcggacgtc ggcgtggacg
     3781 tagtccgtga cgccctccgg ccggctgatc agcagcgcct ccgcgtgacg caggacgatg
     3841 gggtcgttgt cgcagtagac gacccgggcg gaggggcgga tctcctgggc cacctggtgc
     3901 aggttgggcg cggtgggaat gcccgtaccg atgtccagga actgcgtcac gccctggccc
     3961 gccagccagg ccgtcgcgcg gttcatgaag gcgcgctgct ggtgggcgcc tatcttcgcc
     4021 tcgacgggca ggagttcggc cacttcctgg tccaccgggt agttgtcctt gccgccgagc
     4081 agcgcgtcgt agacccgcgc cgagtggggc ttgctggtgt cgatcggggg gtgaggcgcc
     4141 tgtgccgtca taccgaactc cggatacacg tggtgtggac cattcagtcg acgcagtctg
     4201 ccacacgcct acggggcccc ggcggagacc cagtgaccca ccagatccgc gtagagcggg
     4261 ctgctgtcca ggagttgggc gggagtgccg acggccgtgc gatcgccgtc gagcaccagg
     4321 acgcgcggcg cgcgcagcgc ggagctgatg cggtgcgcca ccacgacgag cgtggtgccc
     4381 cggtccgcga aggcccgctc ggcccgctcc tcggccgccg ggtcgaggtg gcagcacgcc
     4441 tcgtccagca gcacgatcga cgcgggggac acatgtgcgc gggccagcgc cacgagctgc
     4501 cgttcaccgg aggagagcgg gggcccgtcc agtccgacgg gcgcgtccag gccgccgagc
     4561 cggtccacga gggtccgcgc gcccacagcc gtcgccgacg cgaggaggtc ggcatcccgg
     4621 gcctgcggat gcaggtagcg caggttgtcc cgcacggtgc cggtgaacac gtacgcctcc
     4681 tgcgggatca gggtcaccgc ccggtggagc caggcccggt cgacctccgt cgccggtacg
     4741 cctcccaggg tcagccggcc gctgtccggc ccggccatcc cggccagcag cgtggtgaga
     4801 gtggacttcc ccgcaccact cggcccgacg accgtcagat gtgagccggc cgggatgtcg
     4861 agggagagcc cgtcgatgac gggtgccgct cccgggccgt acgcgtagac gacgttcacc
     4921 agggacaggt ccggggagcg cggggtccgc ggggtccgtg gggggagggt cgggcccgga
     4981 ccccccggag ggccgggccg cgcttcccgt gtcgatcggc tcaactggct cagtacggtc
     5041 accagttgca cgccccagga gccgagtacg gtgacgagcg agcgcagggc cggagccact
     5101 ccgctgacca gatagctggt cgcgcccagc agttcgccca ccgacagcgc cccgctgtcc
     5161 aggagccgcg gggccgacaa cagcaggacc agcagcggga gatggctgcc cagcgacacc
     5221 agcaaggtgt tggccgacgc ggtccgggca accgccctga ccgcgtcccg gtggtcggtg
     5281 atccgggcgg acaggtcgtc ggccacccgg tcccgggcac cgcacgcgac gacgtcccgg
     5341 atgccgtcga aggtctcgcc cgcgaccccc gtgaggcgct cctccgcccg cagctggcgg
     5401 cgctggcggc gggcgaggac gcggaggcgg gggacgcaga ggagcagggt gagcaggacc
     5461 gggggcaggg tgaccgccgc caccggggcg gacagggcgg ccaggcccac gaacgccatc
     5521 agcagggaga cgcccagctg ccgggccgag cgcagcaggg cggacaccag cgaccgcacg
     5581 gtctcgacct ggaccgtcag ccgggccacg cccgcgcccg ccgtgtcccg ggctcccgcc
     5641 gccgcgcgct gcacggcccc tgcggccacg gctgtcacca ggtcgtcccg cagcggttcc
     5701 acgatccgcc ccagccacgg tgtcagggtc cgggtcatca gggcgcggaa gaccatcgcg
     5761 gccccgagca ggccgatcca gaagaagcct tcggcgggcc gtcccgcgag gaagccccgg
     5821 tccagggcgg cggcgacgag cagcccggag gcgagtgccg gaaccgcctc cagcagggac
     5881 catcccgcca ccgcgaccgc cgccccgcgg tgttggcgca ggaacccggc gaacaggtgc
     5941 cggtcgatgg ggcgcggggc tgcctcgctc ataccggctc ctgggcgtgc gggttcgggt
     6001 gcgggggcgt gttccggtcg gtccacgctt cggccccgga tcccgtatcg cggtccggga
     6061 cggtctccgg gccggtgctc gccgcgaaca gcgcccggta gtcgtcgagt tgccacagat
     6121 ccgcgtgcgg gcccagggcg cggaccctgc cgtcctccag ccaggccacc aggtcggccc
     6181 gcgcggcggt cgacacccgg tgggcgatca gcacccgggt acggcccgac caggccgagg
     6241 cgagcgcgga gccgacccgt gcctccgtgg cggtgtccag gctcgacagt gcgtcgtcca
     6301 gtacgaccac cgccggatcg tggaccaacg cccgggcgag cccaaggcgt tggacctctc
     6361 cgccggagag cggggcctcc gtgagcggag tgtcgtagcc acgcgggagg cgggcgatga
     6421 agtcgtccgc ccgggcggcc gcggcagccg ccgtcacctc ctcgcgggag gcgtccgggc
     6481 gggcgaaggc gatcatcccg gccaccgtcg tacccagcag cgcgggccgc tcgaaggcgt
     6541 agccgacggc ggcgcgcagg gcctgggggg tcagctcccg cagcggtacg ccgtcgatgg
     6601 cgaccaggcc cgcgtcgggc tcccgcagcc gcccgatcag cgccgccagg gtgctcttgc
     6661 ccgccccgga ccgaccgacc accgcgagcg ccgtgcccgc cgggacgacg aggtccacgg
     6721 cgtccaggac ggtccgggcg cccgaacgga cggtcacccc cgacagggtc accgtgccgg
     6781 ggcggcccgc cgggcgcgcg cgggtgccgg gggccgggac cggctggtcg acgacctcgg
     6841 cgacccggcg cgcaccggcg gccgacatgc cgagcgcgaa gagggcgtcg agctggtcca
     6901 gtgcggccat cgcgagcgcc gtgtaaccga cgaccgcggc gagttctccc gcgctgatgt
     6961 caccgtggag cagggcgaga cctccggcac agagcaccag cacctccacg gccgggatca
     7021 gcaggcccac ctgccatccg gtgtcccgct ggagcgccca gacgcggtgc ccggtgcggg
     7081 acagctccgg gagaggatcc aggactcggc gcgtctcggc cgccgccgtg ccgctcgcgc
     7141 cgatggtccg ggccccgccg agcgcttcca gcagcagggc ggagattctt ccctgggtct
     7201 cctgataccg gaggaacagc cccgagccgc ggttcatgaa catccgggcg atgagcgcca
     7261 acggcggtac gcccagcgag aagcagagcc cgatccgcca gtcgagcagc cacagcgcga
     7321 ccaccccgcc gagcgaggtg agcaccgccg tcgaggcggt gaccagcgtg accccggccg
     7381 agccggcctg cgcgcacccc gcggagagac gccccgcgag gtccccggcg ggaaagtcgg
     7441 ccgtccccgg aaccccggcg tccagggcgc gccgggcgag ggtccggcgg agggcggcca
     7501 ccgtgccgga gccatagccc ccgttggcga gggtctggag ggacccggcg gtgacgacga
     7561 gggcgaggag cgcggcgcac acgaggacgg ggccggtgac ggaccgccgg gccacgaccg
     7621 cgtccagggc ccgcgccatg gcccagggga acgccagcgt gccggccgac cccaggacgg
     7681 ctgtggcgga ggcgaggacg aaccagccac gcgtccgggc ggtcgcgtcc cacaccagtc
     7741 gccggggaga cgtcatcgaa ctccttccgg ccgtccgtgg ctcccgcccg ggggcggacg
     7801 ggcacgggtg acgggcacgg atcgcggtga gtcgtgcgta cgggagacac ggcgtgnnnn
     7861 nnnnnnnnnn nnnccggcgc acggctgcta ctgctgctcg atgctggtga tggagcaggt
     7921 ccaggtacac gtccgggtgc agccggccag cgcgacggac tcctcgccct ccagggtctg
     7981 cagctcgtcg acgtcgacgg tcatggtgtt gtcgatcatg gtggtgtcct ttcgtcgtgc
     8041 gtgatgtgcc cgaacaccgc cgaggaccgg cggtgtcgca cggccgcgtc ggcgaccgtg
     8101 agttcagggg gaacgagggt gcggcggcgg tccgggaccc gggccgtcag gaagctcacc
     8161 agccggtcgg tgagttcggc gccgccccgc tcctggagcg ggtggtggcc cgctcccgcg
     8221 atgtcgaggc agtcgtgggg tgcgcgctcc gggccgcccg ctttcgccag cgaccggtgc
     8281 agccggcgcg tctcgtccac cggcacgacg gggtcgtcac agccgtgcag ggcgagcagc
     8341 ggtacgcgga tgcggtgggc gaggccttcg acgtcccggg cgccgaggtc gtcgtccggc
     8401 ggctcgccca ggccgtgccg gtcgaccagc gcgcgcacgg cgggcgacga ccgttcgcgc
     8461 agtccgcgcg cggacaggaa cggggcgatc accgcgcagc gtgcccaggc gtacgggtcg
     8521 gcgcacacag ccagcagggc gaggaagccc ccgtaactga tgccgaggag aacgggcggt
     8581 tcggcgtccg gcgggcgctg ctccgtgagc gtacggacca gggagcggat gtccgcgagg
     8641 tcgggcacgc cccatgcgcc gtggatcgcc tccgcgtggg cccggccgta gccggtgctg
     8701 ccgcgctggt tgggggccac caccgccgcc ccggcttccg acaggcgcgc gagcaccggg
     8761 tcgtggccga gcgtccagtg gtcctccggg ccgccgtgca gcgcgacgac gacggtgggc
     8821 gcggtgcgcc ggtcgcccag gacgacggcc tcgaaccgcc cggacggggt ggcgaaccac
     8881 tcggtcgcgg cgtgcggagc cctgggggcg tcaggtgtgc gggccggggc ctcgcgggtg
     8941 tcggacgggg cgtcgtacga ggcggtgtcc gggacggtga ccaggtcggc gggacggtcc
     9001 ggggtcgcgt acacgacgcg cagcccgctc gtgctccagc cggcgacggg gtggaacgcg
     9061 cccggcggca gcgcggcggg ccgggaccgg tccgccccca cgtcgtacag gaagagacgg
     9121 gcctgcgcgc cccgggagac ccgcagcgcc acccgctcac ccgccgggtc ggcggccagc
     9181 ggaaggaccg cgccgtccag ggagttgagc cggtccggga agctgagccg ggcccggtcg
     9241 ccgagggcgg cgtgggcgat tcgcagccgt ccgtcgccgg gatcgctcgc cgtcagcagc
     9301 agccccgagg caggtgcaga gagcagcagc cggtggatgc ggccgttcgc cggcgacggg
     9361 agagcgtgcc acttcccgtc gcgcaggtcg agagagacgg ggcggtatcc gtcgggccct
     9421 tcgaggtccg tggcgtagcg gcagcccgtc ccgtccagcg gcaggagggc ggtgacccgg
     9481 cccggcagga tcacgggatc gctcagccgc agtggcgtgg aacggacccg ccggacccgg
     9541 gtacggccgt cgtgggaggt ctccaccgcc agcgcgagcg tgccgggcgg cccgccgggc
     9601 accaggcgca agcctcgcgc ctcgacgacc aggtcctcgg ccggggacgg gtccttgagc
     9661 tcgggcccgg ccgggtacgg cacctggggc tcggcgagcg aagtcccggc ggccgtggcc
     9721 gaggcgggcg cggggcggga cagcagaagc aggtggcggc cggagcccgc cgtgccgcgc
     9781 agccgcagca gcccgccgtc ctcggtcggc agcacctggg ttgcggtggt ctccgccggg
     9841 gcgccctccc ggtagcgggg cgtgtcaccg gggtacggag ggtgcgtgcc gtcgaggtcc
     9901 caccaccccg gggccagcgc gccgtcggcc gtggccacca gacatgcggc gaaccgggac
     9961 cgcgccgaga agcggaagct gatgcgctcc ggccgccggt tcatcgcacc cccaccgcgg
    10021 tacgcgggtg ccggccggcg ggcgcgaaga gttccggggt gtccggcatc cagagccgcg
    10081 ggcccccgtc ccgcaggcgc agcagcatgc cgaccgttcc ggcgacaccg gtctggtagc
    10141 cgcccgtgac cgcttccagc gactcgtcgg gcaccaccag caggccgtcg cgtcgtacgg
    10201 cacgggtgtg gatgcaggtg gccagctccc ctgcctggtc gcggtaccgg gggtcgccga
    10261 gcgcggcgga catgtcgagc aggaactccg cgttcccggc gagcccgtgg caggcggcgg
    10321 gggaggagag ccacatggcc tcccgtactc cggccgccgc gcgtacggca gcctctcggt
    10381 ggcgttcgtc gccggtccgg gcccagagcc ggaccaggaa cgtgccgatg cccgaggagc
    10441 cgctgcacca gtgcgtctgc cccaccggcc cgtcggcgtc ccggtccccg gccggccaga
    10501 ccgcccggcc ggcctcgaac cgggccagct tcaccagggt gtcgcccgcc ctgccggccg
    10561 cccagaggag gccctcgtgt tccgccgcca ccccggcggc cagcaggaac gcgccgatcc
    10621 ccgcgatgcc gtgggcgaac ccgtagtggc gggctccggc gaggttcgag tcgaaggcgg
    10681 ccgggacggg ccagatcacc ccggcggggt gatcctcggc cgccgagatg atcgcctggg
    10741 cgcaggcgac cgcccggtcg cggaagaccg gatcacccgt cgtccgccag aagtgcagtt
    10801 gggtcatgcc ggcccccgcc gccccgtggc agatgtcccg gttgggccag tcgaggggga
    10861 ccgcgcgcgc gagtgcggac gcctcggcgg cgacgtcctc gtcgcccagc agcagggccg
    10921 cgtcgagcag tgcccaggcc gtgccggagc ggccgaagtg cagcccgggc aggagcgttc
    10981 cgtcgggtgt ccggccggtg gggagatcgg cgagacgccg ccgtgtccac tccgtcagct
    11041 ccgccacccc gtcccggacg tcgggccccg cgcccgccgc cgcggcccgg gtgagcacgg
    11101 cgaggacgcc ggccgagccg tactggacgt tcagcgggtc ggtggtcgcg ccgaatgcgc
    11161 tgacgtccca gaggtgtccg ccgctgccgg gcccggtgcg gagcaggtac gcgatgccat
    11221 cggcgatcag ccgctcgcgc tcctcaccgg acagggccgg aacgccgctc ccaccggtgg
    11281 cgcccgttcc cgtcacccgg gctccgccgg tctctccgcc ggtggaccgg tggccggttc
    11341 cgggcagctc cgcgagagcc ttccgtatgc ggggcagccc ccagcgttcc tcggggagcg
    11401 gggcgcagag ggcgaggagc aggggcagaa gcggtgcggc ccaggggtga tcggcgatcg
    11461 ccggcgtgat cagggcctgc gtacggtcgc ccatcgggcg gtcgtcgggg accaggagca
    11521 tgtcgacacc cgtcgccagg tggagcagca ccgcgccgag gccgtagaga tcgcccgcgt
    11581 acgtgggagc cgtgaagtcg tagtcccgca gcgaggacac ctcggggccg acatagccgg
    11641 gggtgtaccc gcggcggacc gggacgccct cgggggccag gtactcgacg tcgatgagcc
    11701 ggacccggcc ttccggcgtg accatgaggt tgttcggcga gaggtcgcgc agcacccgcc
    11761 cggtgccgtg gacggccgcc acgatgtcca cgatctgccg gcccagggcc aggaactccg
    11821 cgaggttccg caccgggcgt tccaccagcc ggtcgcgcag cgtttgcccc ggtacgaact
    11881 cctgggccag gaaaaggttg ccgccctggg cgaacaactc gatcgcggcc ggggtgaagc
    11941 ccagtgggtc cagcgcctcc agcatctcgg cctcgtggcg cagggtgtcc tggaggtcgg
    12001 tgccgtccat gcggacgccc acgtgcgccc gcgcctcctt caccacgacc tgccggccgg
    12061 tggtctcgtc ggtcgcgagg tacaccccgc ccttgaaggc gtgccggatc gccttggcga
    12121 ccacgtaacg gccgttgagg cggacagact tcctccccgg tgtccgcgtc ggcttctgcg
    12181 gtccggccgg ctcccgcgac gggctcggcg cggcctcggg ggaaggcgcg gtctccgggg
    12241 aagccgccgg ctccgggaac ggcggcggtg cccacgcggg ggtggtgacc caggcctgac
    12301 gccggtcctt ctccagcccg ccgccggggt tgcgcagccg tacgtccgtg tccccgtcgt
    12361 tcgtcgtcgt ccgcaccccg ccgaacaccc cgtagcggta gtggacgagg ctgcccgggg
    12421 cgtacggccg gtccgagagg atgcgtggtc cgcgcagtcc cagcgtcgcc gcatgcagcc
    12481 gccgggccag ccggcggaac agctccgggt cgtcggggta gaccgtgatg aacttgccgc
    12541 cgccgccgcg gtcggcgcgc cctcccgtca gcagggcgac ccggtccagg gcccccgcga
    12601 acttgaacga ggcccgttcc tcgaccagga catcggccgc caccgccagg accagggccg
    12661 cggacagcgg tgtggccgac aggtgcagct tccagccctg ctcgccgctc cggtggccgc
    12721 gcggccggac cgagcaccag aactccccct gctcgaccgc ccactgcgtc gcaccgcgcc
    12781 ggtgcagcac cccttcgacg atgccgggca gcaggccggt gtccagcgcg aagaagctgc
    12841 cgccgtcgtg ttcgtcgcgg tcggtgctca caggcgatcc ttccttgccg gtgcggtgtg
    12901 gtggcgggac tctgacggtc cgggcggagc cggtgcgcgg tgcgggagtg gtgatgaccg
    12961 catatgacga atcgtcatat gcgtttcggc cagggcgcat cgaaagatct gccgagttgt
    13021 ccgggaatcg cggaccgtcc tcggccacct ctgcctatcg tggcggcgag cgatcccccg
    13081 atcgccacgg gtgacgttag cggtgtgccg aggggccggt gcaccacccg ttctgggggg
    13141 ttgcgatcaa ggggggccgt cggatcgaca gaaccgaaac cgggctgcac cgggcccgga
    13201 aaaccatggt catcgccacc gcgctgtatc gcggcagcca cctggtcgcg gggggtgtcg
    13261 tggtcgcgca gcaccagcgc gaccgcctgt tcccgtggct ggccctgagt gccgcgatcg
    13321 cgtccaccgc gctcatctgg ttcatggcag cccggcaccg gcggctcgtt ccctgggtcg
    13381 tgggactcga cgttctggtg atcggctgcc tgctgccctt cggcgcgtac gcctggggcg
    13441 gggcccgcac ccaggagtcg gtcgcctggg tcatgctcct gggcggatcg gcttcggcca
    13501 tggccgccgt cgccttcgga gcgcgcctcc tcgccgtcgc cgtggccctc ctggtggcca
    13561 cccatctcgc cgggtacctc atggtggagg cggacgccgc cgtgaccggc gcccatctga
    13621 acgccctggt cttctccgcc gtcgtgtcct gggtgctcac ctggtacctc tgccgacagg
    13681 gcgagcaggt cgattcggcc aaccggcggg cgcttgccgc tgaggcacag cgggccaggt
    13741 tcgcggagcg cgtcgcccat cacaacgcgc tgcacgacac cgtcctcgcc acgctgacgg
    13801 ccatcgcccg cggcggcgtc gacgccaaca cctcgatgat gcgcgagcgt tgcgcgcggg
    13861 aggccgccta cctcaggagg ctggtcgagc aggcggacga ccgtgagccg gcctccgagg
    13921 tgcgggcggc acttgaagag tccgtacgcg ccgccgaagc gctggggctg cgggtgaccg
    13981 cccgctacca cgagccgccc gccgtgcccg gcgagatagc gctggccatg gcacgggcca
    14041 cgaccgaagc cctcaacaac gtgcggtgcc acgccggtac ggggcacgcc ttcctgaccg
    14101 ccgtcggcga ctcgggccgg ctggtcgtca ccgtggtcga ccgaggccgg ggtttcgcta
    14161 ccggatccgc cggaccggac gatgcgggcg gagtagccgg accgagggca tcgggcggat
    14221 cggaggggcc ggccggtccc gccgggcagg ccgccggcgg aatcgggctc gaccgttccg
    14281 tgtacgcccg gatgcgcggc gtgggcggcc gggccttcgt ggacagcgcc cccggcgagg
    14341 gcgtccgcgt ggagctgaga tggccggggt gatcaccgtc gccgtggtgg acgacgaccg
    14401 gatgctgcgc gacggcatcc gttcgtggtt cgcgggagtc gaggagctgg acctcgtcgc
    14461 gtgcgcggcc accgtcgacg agttgctcgc gggcccctgg gagccgccgg acgtcgtcct
    14521 gctggacctc atgctccggg acgaccggcc gcccgccgac aacatccgcc gccttcgggc
    14581 ggctggcagc agagtgctga tgatcagcgt ggtggcggac cgcgaccgga tcgtcgcggc
    14641 catcaccgac ggcgccgacg gcttcctcac gaaggaccac gagctgtccg tcctcgtcga
    14701 agccgtcggc gagatcgcgg ccgggcgcac cacccactcc ccggagctgg ctttcgccct
    14761 ggcctacgac cggggctcga cccgcccccg gctctctccc caggaacgcg aggtgctggt
    14821 ggggtacgcc tccgggctca cgctgaaggc gaccgcccgc cgtgccggga tcacggtgaa
    14881 cacggcgaag tactacctgg accgcgtgaa ggccaagtac caggagacgg ggcggcccac
    14941 ctacaccaag atcgacctgg cgacccgggt ccgcgaggac ggctggcgtt gacccgcacg
    15001 cgggcggcat ccgaagatcg ctggtgtgag caacccttct gacccgcctc cgccctcgcc
    15061 cgcgccctca ccctcgggcg aaccgccccg tacggacggg cccccctccc cctgggccca
    15121 gccgccgcac ccgcccgcac cggcctggcc gggcgggccg gcggggcagg cgtggcaggg
    15181 cgggcagggc tgggacaggc ccccggagtg gagccgcccg ccttccgggc ccgtgcgcgc
    15241 gcccgccggc tcccgctacg acgagcaggg gcgcaacggg cagggcggac ggttcggctg
    15301 gctcggtgag ctggcggtcg tcgtggcgct ggtcgtggtg ggcgtcctgg tcgtcagcat
    15361 cgccgggttc gtcgtcgcgg agctgctgga cgcggggccc gactcggcgg acagcgaact
    15421 cttcttcgag gacccggtcg ccgatctcgt cgtccagctc ctcggcctcg cgatcggcat
    15481 ccccatcgtc ctgctggccg tccggctgct gggccgccgc cccgccggaa ccgtctcctc
    15541 cgtcgtcggg cggatccgct ggggctggct cctgcggtgc gccgccgtgg cgtttccgct
    15601 gatgatcgtg cagatcggcc tgctgatcgc gtggacctgg aacgacgagc cgctcgggga
    15661 gacggggacc ggcttcccgg ggtggcccgt ctttctgctg agcctggccg tggtgctggc
    15721 gctcgtcccg ttccaggccg ccgccgagga gtacgtcttc cggggctggc tggtccaggt
    15781 gatcggccgc gccgtgcgga cgccgtggcc cgcgatcgtg atcgcctccc tgctgttcgc
    15841 cctggcccac gggttcggcg aactctccgg cttcctgctg ctgttgtact cggcgctgtg
    15901 gtggggctgg ctggtgatcc gtaccggcgg tctcgaagcc gtgatcgtca tgcacgtcac
    15961 gaacaacctg ctggccttcg gcctggcggc tggtttcggc gagctggcca gtacggagac
    16021 cgcggccgac gcgccctggc aggccatggt gatcgagctg gtcttcgccc cgctgtactg
    16081 cctgaccatg gcccggatcg cggaccgccg cggggtcgag cgcgtgagcc cctgaggggc
    16141 cggagccggg gccgttgcgc tgcgcggagt tactcgaccg ctgagggggt gcggcggggc
    16201 gcgcgccggg tccgtggaaa gctaccgcga aggggcggcc gcggggccgg ccgggacggg
    16261 gaggccctgt ggagcgtacg aggctgtgga agtccttcgt cccggtggtg gtgaacctga
    16321 tgctcgggat tccggccgtg gtgccggtct tcctgatctg gtacgtcctg tccaacgggc
    16381 ccctggcgga gctggggtgg acccagcggg aaccgaccga gaacgacggg atgctgccgt
    16441 ggctgatcct cgtcgtgccg gtggtggccg gcttcggagg tctctggacc ctgatcaacc
    16501 tgtggatgcg gcgccgtctg atcgctgcgg cttccccgta cccgtactgg tcggtgtccg
    16561 tgacgctgac tgtcgccccg ttcctcctgg gcgtggcctt cggctgagga acgcggcggt
    16621 gcaggccagg gcgatggcga gaccggccga cgtacgcagg agcacggtga ccgacggggg
    16681 caggtgttcc accgccgagc cgtcggcgta gacgcaggcg ttgcgcaggg gccagaactc
    16741 ctgctccaga ctcaccagcg gggcaccgga catgttcatg tcctcgcaca gtgccgggaa
    16801 cgggcctccg agggtgacgg agaaccagcc ggcgcagtac acggccgtgg ccgcgaagcc
    16861 gcagagcagg gcggcgaccc cgcagatcct ggccggcgaa cggggcgggt tcttcagcag
    16921 gagagcgagc accagggcgc aggcggccgc ggccgccgcg ctgagcagca gaaacaggcc
    16981 cgtcaacggc gtcggcacgg ccacgtcctc tctcggccgg gtcagaaggg cacggtcagt
    17041 tgtgcccgga cgtgcgcccg cagtacgccc gccatgtccg tcgcgcagtc gctgatcagc
    17101 cactggatct ggaggccgtc catcagcgcg atgagctgct gcgcggccgc cgacggatcg
    17161 acgtcgtccc ggagttcgcc cgcctgccgg gcctggaggt aggcgcgttc ggtgttggcg
    17221 accgacgtac ggtagcgggc ctcgaagtac gcgtgtgccg ggtggtcggg ggcggtggcc
    17281 tccgccgcga ccaccgagaa cagctcgacg atcccgcgcc gcttggcgtt cagctccgcg
    17341 aggtcggtca gccggcgcag atggtcgatg ccccgcgtca cgcccaggga cagccactcg
    17401 tcgtccacgt cgtcacggcg ctggagcacg gcgaggagca gggcctcctt cgtcgggaag
    17461 tggtgcagga ggcccgggtg ggagatgccg cagcgggtgg cgatgacgcg cagcgaagcg
    17521 ccccggtagc cggcctcgcc gaacagggcc atcgcctggt cgaggatctc ggtccgcttg
    17581 gcccggccct tggcgtagcc gcgccgggtt tccggggtca cgcgtattca cccgttgtca
    17641 tcggacgcct ttctcgttcc gccccagatt ctcgcagggg cgaatactta ccaagcggtc
    17701 gggattgagc gtacggtact gcggagtgcc gtcgtggccg tcgtgaaagg aagtcctgtg
    17761 ggtctcaagc cgccgtatct cgaccccgag ctgcccgtcg gggaacgggt cgccgacctc
    17821 ctggggcgca tgacgctgcc cgagaaggtc ggccagatgc tccagctcaa cgcgaaggag
    17881 ggggtgcggc acctcgtcga ggacctgcac gccggctcga tcctgcacgc ctcgccggac
    17941 cgggtgcgcg aggccgccgc gctcaccgcg aagacccggc tgcgcatccc gctgctcgtc
    18001 gccgaggact gcatccacgg gcactccttc tgggagggcg ccacgatcta cccgacgcag
    18061 ctcgggatgg ccgccacctg ggacccggag ctggtggagc ggatcgcgcg ggcgacggcg
    18121 gtcgaggtcg cggcgaccgg ggtgcactgg acgttctcgc cggtgctctg catcacccgg
    18181 gacctgcggt ggggccgggt gagcgagacc ttcggcgagg acccgctcct gatcggtgag
    18241 ctggcctccg cgatggtgcg cggctaccag ggcgacggcc tcgacgaccc gaccgcgatc
    18301 ctggcctgcg ccaagcactt cgccgggtac tccgagaccc agggcggccg ggacgccagc
    18361 gaggcggaca tctcacggcg caaactgcgc tcctggttcc tgccgccgtt cgagcgggtc
    18421 gccaaggagg gctgccgtac gttcatgctc ggctaccagt cgatggacgg cgtgccgatc
    18481 accgtgaaca actggctgct caacgaggtg ctgcgcggcg agtggggcta caccgggacg
    18541 ctggtcaccg actgggacaa cgtcggccgc atggtgtggg agcagaaggt ctacgccgac
    18601 tacgcgcagg cctcggcggc ggcggtccgc gcgggcaacg acatggtgat gaccacgtcg
    18661 aacttcttcg agggggccca ggaggcggtc gctcagggcg agttgtcgga gacggagatc
    18721 gacgccgccg tacgccgcat cctgacgctc aagttcgagc tgggcctctt cgagaacccc
    18781 cgccaccccg acgccggccg ccaggccgag ttcatcggca gcgccgcgca cgccgagctg
    18841 aacctggagg cggcccgccg ctcgctggtc ctgctgacga acgacggcac gctgccgttc
    18901 gctggcggcc tggaggccgg agaggagggg cgggccacgg ggtccggtcc ccgtacggtg
    18961 gcggtcatcg gccccaacgc ggatgacgca cagacccagt tgggcgactg ggcgggctcc
    19021 tccgggcagg ccgactggct gccggacggc cagccacgcg ccatgatccg tacggtcctc
    19081 gacggcttcc gcgaccgggt gcccgccgac tggaccgtct cgtacgcgcc cggcgcccgg
    19141 atcctggatg tcgggcccga tccggagggg gagttcttcc cggacggcca gccccgcccg
    19201 gaggtcgtcc acccggccgc ccccgacgcg gagttgatcg ccgaggccgt ggccgccgcc
    19261 gaggccgccg accatgtggt ggccgtcgtc ggcgaccgga tcgagctgat cggcgagggc
    19321 aagtcgacgg ccaccctcga actcgtgggc gaccaggtcg cgttgctgga cgcgctggcc
    19381 gcgacgggca agccgctcgt cgtggtggtc atcagctcca agccgctggt gctgccgccg
    19441 tccgcgctcg gtgcggcggc gatcgtgtac gcggccaacc cgggcatgct cggcggtcgg
    19501 gccgtcgccg aactgctcct cgggctggtc gagccgaccg gccggctgcc gctgtccttc
    19561 gcccggcacg cgggccagca gccgacgtac tacaaccagg tgcgcggcca gcacggcacg
    19621 cgctacgcgg acctcaccca gcgcccggcg ttcgcgttcg gtgaggggct gagctactcg
    19681 accgtcgcct acacggacct ggaggtgctg acggcggtgg tcgacgagtc ggagtccgta
    19741 cgggcccggg tcacggtgac caacaccggt gcgcggcccg cgctggagac ggtgcaggtg
    19801 tacgtgagcg acacggtgac ctcggtgacc tgggcggaga aggagctgaa ggcctaccgc
    19861 caggtggagc tggcccccgg gcagtcgcgc gaggtcctct tcgagctccc ggtcgccgac
    19921 tgcacgctcg tggacgcggc gggccgccgc atcgtggagc cgggccgctt cgagctgctg
    19981 gtgggcccgt cgtcccgcga cgaggcgctg ctgcgggggg agttcacggt caagggctga
    20041 gccccggacc gtgacggccg agccgccgat gggaccgccc cgcgcctgac ctcgggagcg
    20101 gtcccatcgg tgatgtcccc gtagccgtcg gacgtcagcg gacctcgaag aagtccacgt
    20161 tgtgccggtt gaccttgatg ccgagcttca cgaagccgcc cttgccgtcc tcgcccgcgt
    20221 acttgcccca gtactggcag tggaagccgg tctcggtctc ctcgtccacg gccttggccg
    20281 cgggcagctc ctcgcaggag agcttgctga tgtcggaacg gttcttgttg gcggtccaga
    20341 gccggtcgta ggcgttctcg gcgaccagga ggcccttctt cggggtgctg ttgtagaagg
    20401 tcaggaagct gcccggcttg tacttctcgc tgatctcgat ctcgtacggg acggtcgcgc
    20461 cctcgtaggt cacgttgcag atgctgacgg cactggcctt ctgggtcacc ccgtccgggc
    20521 agttcgcgct ggtcttcccc ggcaccttga ggcggccgag caggtcttcc tggagcttgt
    20581 gctcgacctt ctcggtgaac gacgcgccgt tggcgggctt cggggtgacc ttgagctggg
    20641 ggtcggagct ggacgcgagg acgtccggct gcggcccggt caccgggacc gcgaggtccg
    20701 cgcccggctc gggagccttg gcctcctcgc tgggggcctg gcgggcggat ccggtcgatc
    20761 cggaggagcc ggcggagtcg tcgctcgacg aggagccgca accggccgcc agaatgccga
    20821 cggcggccag cccgatgagg ttcttggaga tacgcataaa gggagcctaa gttgcgcctg
    20881 tgacaaccct gtgtggccga tggggccgct gggagccctg agcgggtcgg ccaaaaggta
    20941 cgtgaagcac gagaacggtg cgttccggtt tgcgaaccgt acgttctgtg accttgacgg
    21001 tggctcagtc gagaaggacc cgtggctcga ctgtgacggt cggctcggtg accggggccg
    21061 gggccggggt gcggtgacgc cgacccctgc cccgtacgtc agggtcgaac cgaagggccg
    21121 ctgccggagc tcccggtgga gcgcgtcagc ttgtacaggt cccaggagtc cgggtcgccg
    21181 atgtactggt agagggtggg ccggctctcc gtgccgccga tgttccatgt gtcgtacgag
    21241 catgcgtcga agctcacgtc gaccccctgc gaccagcggt ccgcgccggg ctcgaaggcc
    21301 caggtgccct gccccgtaca gctgttgtgg ccgtcctgcg ggtccgacga ctcctggtcc
    21361 gtcgcgtcgt actcgccccg gacgtcgagc gcttcctcgt cgacgtcgac ggcggtgacc
    21421 cggccgtccg cggtgaaggc gagcgtcccg ccccttccgt cggaccaggt gccgacgatg
    21481 tccgccgatg tgaccgccgg tgggcggtac tcccggagca gccccgtcgc caggccgacg
    21541 ccgccgagga cggcggtgag aaccacggcg accacgcccc acagcagtac gggcccgaag
    21601 atccgctccc gccgcgaccg ccagagcagg gccggaacgg tgagcgcggc cgtggtcagg
    21661 caccagccca gaacgacggc gacgggcccc gcgccttcac cggacaggac gacgaccacg
    21721 ccgaccgtca ggagcgagac ggccgccgcc accaccggaa cccaccacca cacctcgcgc
    21781 ccgccgaacc ggcgtcccag cacatcgctc aaccaggcgg tcgggaggac gagggccagg
    21841 gacaggacgg ctgcggcact ggtcgtgaac acggcgagca cgggcagcag caggacgaac
    21901 atcgccgaac cgccgacgcc ggtgttcggc gactcctgcg tgacgccgta cacgatgctc
    21961 acgacgagcg cgatcgccgc ttccaggtgc aggaccagga tcgagagcag cagtgacagg
    22021 ccgaacaatc gcttgttctg caccgttaag tcccccttgc gcacggtgat gtacgcggca
    22081 cgcccggccg gggcggcagc tgtgaccatc gtggcagagc tgtttgaacg tgttcaacgc
    22141 ggggttcgcc gtgcgatgcg gcgcatgtga gggccgagcg ccggggcgca tccggggcgc
    22201 gcaaagaaga agcgtttccg cgtgcgggta ttcccccgta cgggtgtggc gcggccgtcc
    22261 ggacggcggt ggggcgagca caatggggcg gcggttcgtg cagaggcgcg caggcccctc
    22321 tcccgcacct tgcgctcaag gaggaccggt ggcggagagc tggacggttc agcggaccgg
    22381 gcccggggat gtcgcgcgcg cccaggcgcg ggaacaactt ctggaagcag ccagggagtt
    22441 gtacggcgtc aacggatacc gggagaccgc cgagcacgat gtgtgcgagg cggccggcgt
    22501 gccggtcgag gtgctgcgtc aggagtacgg ctcccgggag gggctcctca tcgccctcca
    22561 caaccgggtc acgacgaccg ggctgcgggc ggcggagagc gccctgctga ccgagggcat
    22621 cgaggagtgc tcgatcgcgg agcgggtccg acggctcttc gacgcctatg tggaggccgt
    22681 caccagcgac ccgcgcgagg cccgcgtgac gttcgtcgaa gtgctgggcg tgagcgccgt
    22741 ggtggacgag cactgcaagc tctggcgggc gctgtggacg gagttcctga ccggcgaggc
    22801 cgagcgtgcg gtggagcgcg gcgaggcgga ggaccgggac caccgggtcg acgtgatggt
    22861 gatggtcggc a
//
