LOCUS       NZ_CP074380            22644 bp    DNA     linear   CON 27-MAY-2024
DEFINITION  Streptomyces sp. MST-110588 chromosome, complete genome.
ACCESSION   NZ_CP074380
VERSION     NZ_CP074380.1
KEYWORDS    RefSeq.
SOURCE      Streptomyces sp. MST-110588
  ORGANISM  Streptomyces sp. MST-110588
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1  (bases 1 to 7915503)
  AUTHORS   Booth,T.J., Bozhueyuek,K.A.J., Liston,J.D., Lacey,E. and
            Wilkinson,B.
  TITLE     Bifurcation drives the evolution of assembly-line biosynthesis
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 7915503)
  AUTHORS   Booth,T.J., Bozhueyuek,K.A.J., Liston,J.D., Lacey,E. and
            Wilkinson,B.
  TITLE     Direct Submission
  JOURNAL   Submitted (10-MAY-2021) Molecular Microbiology, John Innes Centre,
            John Innes Centre, Norwich, Not US or Canada NR4, United Kingdom
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: 28-FEB-2016
            Assembly Method                   :: HGAP v. 3.0
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 25.0x
            Sequencing Technology             :: PacBio RSII
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_022695595.1-RS_2024_05_27
            Annotation Date                   :: 05/27/2024 05:38:09
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 6,918
            CDSs (total)                      :: 6,828
            Genes (coding)                    :: 6,327
            CDSs (with protein)               :: 6,327
            Genes (RNA)                       :: 90
            rRNAs                             :: 7, 7, 7 (5S, 16S, 23S)
            complete rRNAs                    :: 7, 7, 7 (5S, 16S, 23S)
            tRNAs                             :: 66
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 501
            CDSs (without protein)            :: 501
            Pseudo Genes (ambiguous residues) :: 0 of 501
            Pseudo Genes (frameshifted)       :: 350 of 501
            Pseudo Genes (incomplete)         :: 185 of 501
            Pseudo Genes (internal stop)      :: 14 of 501
            Pseudo Genes (multiple problems)  :: 45 of 501
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 12:56:23
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 7081991
            Orig. end                         :: 7104635
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP074380.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            Bacteria and source DNA available from Barrie Wilkinson, John Innes
            Centre, Norwich.
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..22644
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="lassopeptide"
                     /region_number="30"
                     /rules="(PF13471 and Asn_synthase or micJ25 or mcjC)"
                     /tool="antismash"
     cand_cluster    1..22644
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PF13471 and Asn_synthase or micJ25 or
                     mcjC)"
                     /kind="single"
                     /product="lassopeptide"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..22644
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:12644](+)"
                     /cutoff="10000"
                     /detection_rule="(PF13471 and Asn_synthase or micJ25 or
                     mcjC)"
                     /neighbourhood="10000"
                     /product="lassopeptide"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..12644
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="(PF13471 and Asn_synthase or micJ25 or
                     mcjC)"
                     /neighbourhood="10000"
                     /product="lassopeptide"
                     /protocluster_number="1"
     misc_feature    complement(1722..1736)
                     /note="TFBS match to IolR, Regulator of the inositol
                     catabolism, confidence: medium, score: 20.21"
                     /tool="antismash"
     misc_feature    2045..2059
                     /note="TFBS match to VqsM, Regulator of quorum-sensing
                     signalling systems, confidence: medium, score: 18.0"
                     /tool="antismash"
     gene            2460..3506
                     /locus_tag="KGS77_RS30960"
                     /old_locus_tag="KGS77_30740"
     CDS             2460..3506
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0000155 - phosphorelay sensor kinase
                     activity [Evidence IEA]"
                     /GO_function="GO:0046983 - protein dimerization activity
                     [Evidence IEA]"
                     /GO_process="GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1048: sensor
                     histidine kinase"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: protein motif:HMM:NF014567.4"
                     /locus_tag="KGS77_RS30960"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KGS77_30740"
                     /product="histidine kinase"
                     /protein_id="WP_242586409.1"
                     /transl_table=11
                     /translation="MLHRAGAYRLPPTWRDLAVTVVLLYGVFTVFPAGTGLLGRQTALD
                     DGSPVVGPVDVLLQLLVSAMALPVYMGLAARCRESRSPAWRRRCALLAGAGLLLLTAAV
                     PVVGVAALCFLGGGVLRERRALGRPRPAAPPPAEPGLVTEARQEERSRLRRDLHDGLGP
                     ALAGIRLQLETAQARLQREPDARRLVAAAAAQTAQAVQEVHRVIDGLRPADLEEDELPG
                     ALRRLARRMRNTSVAIAVRTPERPARIAPVTEVAAYRIAAEAVTNAIRHADADRIEMRL
                     TTGEETVVLDVIDDGVGLHPGSPRHYAVGVTSMARRAADVGGRCVVASRRGPSPGTVVH
                     AELPRSPR"
     misc_feature    2487..2489
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            3503..4162
                     /locus_tag="KGS77_RS30965"
                     /old_locus_tag="KGS77_30745"
     CDS             3503..4162
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1016: LuxR family
                     DNA-binding response regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020123196.1"
                     /locus_tag="KGS77_RS30965"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KGS77_30745"
                     /product="response regulator transcription factor"
                     /protein_id="WP_242586410.1"
                     /transl_table=11
                     /translation="MTIRAFLVDDHPLFLTGVRVALQDAGVAVAGEAHSGEEALKQLRA
                     TGARIDVVLVDVQLPGCSGIEVARAITSGGAPEGHRPRVLMVSMSQDDDVVVAALRAGA
                     HGYTLKSAPREELLRAVRIVADGGAVFSPSVAGRLATYVSMGRDLPGRAAFPELTDRQR
                     QILDLLARGYDNRRIARELVLSEKTVRNHLSHVFTRLRVNDRTLAAVRARDAGLGT"
     gene            4397..5485
                     /locus_tag="KGS77_RS30970"
                     /old_locus_tag="KGS77_30750"
     CDS             4397..5485
                     /GO_function="GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1020: major
                     facilitator transporter"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018889538.1"
                     /locus_tag="KGS77_RS30970"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KGS77_30750"
                     /product="MFS transporter"
                     /protein_id="WP_277994336.1"
                     /transl_table=11
                     /translation="MLWCGETVSGLGNGITVVGLPLIAVQVLDAGSTAVGLISAAVWLP
                     WLLVGLPVGAWVDRMRKRPLMIACDLVAATALLSIPLATWRGALALPQVIVVALVCGTS
                     AVCFNTAYHAYIRIVLDGRDLLEGNAELQGGEAATQVAGPGVAGALTQALGAVAGLVAD
                     AVTFLVSAVCLRRIRAVEPDPAPDGERDLLRRQILQGLRFVGRDRYLRWMVTWGAVINM
                     ALMGCQAGQVVFLVRTVGLDPATVGLLLFVTGALVVGTGVSVADVVVGTFRQTYCPPHM
                     LGRVVATAMTANHSTIPLGSLLGGVLGDAVGCRRTMWIMTGVIALSWLVLAVGPLRHER
                     DLPRTRAPEQVRRRREGERSAA"
     gene            complement(5515..6222)
                     /locus_tag="KGS77_RS30975"
                     /old_locus_tag="KGS77_30755"
     CDS             complement(5515..6222)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1016: LuxR family
                     DNA-binding response regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004942992.1"
                     /locus_tag="KGS77_RS30975"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KGS77_30755"
                     /product="response regulator transcription factor"
                     /protein_id="WP_242586412.1"
                     /transl_table=11
                     /translation="MSDQIRVLVADDQALLRGSFRVLLEAEPGLTVVGEAATGAQAAEL
                     AARERPDVVLMDVRMPEMNGIEATRAICGSPATAATRVLILTMFDLDAYVYGALRAGAS
                     GFLLKDTPPADLLTAVRVVASGEGLLAPSVTRRLIAEFAGRPEPAQRPSRELAGTTDRE
                     REVLTLIARGLSNAEIAGHLHVSPATVKTHVGHLLGKLGARDRAQLVIAAYETGLVTAA
                     RPRSGMRPEGPGD"
     gene            complement(6219..7541)
                     /locus_tag="KGS77_RS30980"
                     /old_locus_tag="KGS77_30760"
     CDS             complement(6219..7541)
                     /GO_function="GO:0000155 - phosphorelay sensor kinase
                     activity [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1048: sensor
                     histidine kinase"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010982370.1"
                     /locus_tag="KGS77_RS30980"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KGS77_30760"
                     /product="sensor histidine kinase"
                     /protein_id="WP_242586413.1"
                     /transl_table=11
                     /translation="MSEPAPRPVLVQPLGRGQLVVLDGLAALLFATVPLMLLYGRGSPA
                     DAAPDLPLWAVCLIAAGTGLPCAVRRLWPLPVFALVLTLSVLGLALGAVRDPFTAAAFA
                     LYTVALTGSRPRSVPTRVIGGLSTALLLLCTLAGTRGMWNQAPGTALVGCAVLGGAWTV
                     GRAVRDRRAYAQRAAREFAELAVAEERLRIAREMHDIVTHSMGLITVKAAVANHVGRAR
                     PQEAYDALRVIEDIGRGALREMRYLLDAWRTEEGDADAGLAPAPGATDLDRLIDRARLA
                     GITVRREVRGVASLPDGVALTVYRIVQEALTNVVRHAAPTHCRVAVTADGRDVRIEVRD
                     EGRAVPAERRAAPLGDGEAGEGQLCGGHGLIGMRERVAVYGGSFTAGPLSDGGYRVRAR
                     IPYESTVRPAGRTDGHTDGEADGESGGASGEGDRRSDKEAV"
     gene            7709..>8605
                     /locus_tag="KGS77_RS30985"
                     /old_locus_tag="KGS77_30765"
                     /pseudo=""
     CDS             7709..>8605
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014144925.1"
                     /locus_tag="KGS77_RS30985"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /old_locus_tag="KGS77_30765"
                     /product="ATP-binding cassette domain-containing protein"
                     /pseudo=""
                     /transl_table=11
                     /translation="MIDVKNLTKRYGRTVAVDGLSFQVLPGRVTGFLGPNGAGKSTTMR
                     VMLGLDRPDQGQVLIDGRRYDGLREPLRHIGALLEAKSVHGGRSAYHHLLWLARTNRIP
                     RRRIAEVIELVGLESAAGKRAGGFSLGMSQRLGIAAALLGDPRILLLDEPVNGLDPEGI
                     LWIRNLMKQLAGEGRTVFVSSHLMSEMAITADHLIVIGQGRLLADTSMSSFIERNSRTS
                     VRVRTPDPERMHKVLTARGIDVERAADGTLEAVGAAPSEVGELAAANGLTVHEVSARTA
                     SLEEAFMRLTAPAVEYHA"
     gene            8631..9413
                     /locus_tag="KGS77_RS30990"
                     /old_locus_tag="KGS77_30770"
     CDS             8631..9413
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010982372.1"
                     /locus_tag="KGS77_RS30990"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KGS77_30770"
                     /product="ABC transporter permease subunit"
                     /protein_id="WP_242586414.1"
                     /transl_table=11
                     /translation="MSTAAARAVLSAELIKIRTVRSTLWTPLLTFVISVGISLVFAMAF
                     HDRFSAMPPDQQRSFDPVMAGFYGLTFGQLMLVAFGVLTVSSEYTTGMIRASLAAVPRR
                     GAFYAAKTLAGTLVAAAVSVLTTVVTFFTAQSTLGPHGVSLGDPGVLRATLGTCLYMTL
                     ICAFSIGVATMLRSSVLSLGILIPLFFIVSPVLANIPALRAVAQYLPDQAGLQIMRVVP
                     RTTDLGHDMGPLAGLLVLVGWTAASLLGGYLLLRRRDA"
     gene            9626..9754
                     /locus_tag="KGS77_RS30995"
                     /old_locus_tag="KGS77_30775"
     CDS             9626..9754
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF033521.1"
                     /locus_tag="KGS77_RS30995"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KGS77_30775"
                     /product="lasso RiPP family leader peptide-containing
                     protein"
                     /protein_id="WP_242586415.1"
                     /transl_table=11
                     /translation="MAEFETVYEPPTLVEIGDFADLTLGIWGCPHDWFGLSTPFAC"
     misc_feature    9632..9650
                     /note="TFBS match to HgtR, Hydrogen-dependent regulator,
                     confidence: weak, score: 16.96"
                     /tool="antismash"
     gene            10001..11896
                     /locus_tag="KGS77_RS31000"
                     /old_locus_tag="KGS77_30780"
     CDS             10001..11896
                     /GO_function="GO:0004066 - asparagine synthase
                     (glutamine-hydrolyzing) activity [Evidence IEA]"
                     /GO_process="GO:0006529 - asparagine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lassopeptide: Asn_synthase"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1177: asparagine synthase (glutamine-hydrolyzing)"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF012936.4"
                     /locus_tag="KGS77_RS31000"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KGS77_30780"
                     /product="asparagine synthase-related protein"
                     /protein_id="WP_242586416.1"
                     /sec_met_domain="Asn_synthase (E-value: 5.7e-37, bitscore:
                     126.8, seeds: 78, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEFLVLPDSPAADGIAEAARQAAGRDAARSPARTPSPARTPSLTR
                     TLTHASGRPWLLGDWTDEELTLVTAGPRRLALLGTTRLDAGTARRALAAARTPHDLDAV
                     ARTLPGVFHLAASMDGRTRTQGTLSTYRQVFHTRVAGVTVAAASPAPLTALTGARTDDA
                     TLAVRLLAPLIPWPLSMRSVWTGIDQLPLGSWLHTDADGRSRTVRWWQPPEPDATPRQA
                     AQAVRAALLDALSVRAGRHGTLSADLSGGMDSTSLCFLADTCGADLITHHWKPLDPAND
                     DAHWAAQAAAHLPRARHHVVPARSGPTWYEAPPRPDEARAATEGPFTWNRNRLHMEQVA
                     RTVAADGSGLHLIGVGGDELFITLPTYLWSLARAHPLRSLPVVHRCRAANRWPLRATVK
                     ELLHSGTFARSLAVTADTLADPLRRPTDVRLRWGAEPRMPAWATRDAVEAVRSLLYEGA
                     AAGQPPLAPGRAQHQILENVLFGGANVRQMDAAMARFGVRWQAPFLDDRVVEAALTIRI
                     EDRFRRGSYKPVLAAAMRGIVPQPVLDRRTKGDFGAEAYEGLQRNQRALLEWCQDLRLA
                     ARGLVDAPALRAALLRPGQETYQLAPYEHTLACESWLRSPAGAPAPAVLATGDPR"
     aSDomain        11893..12060
                     /aSDomain="Lasso_Fused_RRE"
                     /aSTool="RREfinder"
                     /database="RREFam.hmm"
                     /description="RRE-containing fused peptidase in a lasso
                     peptide cluster"
                     /detection="hmmscan"
                     /domain_id="rrefinder_KGS77_RS31005_Lasso_Fused_RRE.1"
                     /evalue="1.20E-09"
                     /identifier="RREFam003.1"
                     /label="KGS77_RS31005"
                     /locus_tag="KGS77_RS31005"
                     /protein_end="56"
                     /protein_start="0"
                     /score="29.1"
                     /tool="antismash"
                     /translation="MTLTLPSHVSATDVEDELVLLNERDGRYWHLNRTGAKILRLLLAG
                     HSPEESARLLT"
     gene            11893..12153
                     /locus_tag="KGS77_RS31005"
                     /old_locus_tag="KGS77_30785"
     CDS             11893..12153
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lassopeptide: Stand_Alone_Lasso_RRE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Lasso_Fused_RRE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF05402"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020123202.1"
                     /locus_tag="KGS77_RS31005"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KGS77_30785"
                     /product="lasso peptide biosynthesis PqqD family chaperone"
                     /protein_id="WP_242586417.1"
                     /sec_met_domain="Lasso_Fused_RRE (E-value: 2.9e-07,
                     bitscore: 29.1, seeds: 20, tool: rule-based-clusters)"
                     /sec_met_domain="Stand_Alone_Lasso_RRE (E-value: 1.1e-24,
                     bitscore: 84.9, seeds: 25, tool: rule-based-clusters)"
                     /sec_met_domain="PF05402 (E-value: 2e-12, bitscore: 45.8,
                     seeds: 461, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTLTLPSHVSATDVEDELVLLNERDGRYWHLNRTGAKILRLLLAG
                     HSPEESARLLTRDCPDAAERALADVRALLESLRASRLVKPS"
     aSDomain        11896..12144
                     /aSDomain="Stand_Alone_Lasso_RRE"
                     /aSTool="RREfinder"
                     /database="RREFam.hmm"
                     /description="Stand-alone RRE protein in a lasso peptide
                     cluster"
                     /detection="hmmscan"
                     /domain_id="rrefinder_KGS77_RS31005_Stand_Alone_Lasso_RRE.1
                     "
                     /evalue="4.60E-27"
                     /identifier="RREFam002.1"
                     /label="KGS77_RS31005"
                     /locus_tag="KGS77_RS31005"
                     /protein_end="84"
                     /protein_start="1"
                     /score="84.9"
                     /tool="antismash"
                     /translation="TLTLPSHVSATDVEDELVLLNERDGRYWHLNRTGAKILRLLLAGH
                     SPEESARLLTRDCPDAAERALADVRALLESLRASRLVK"
     gene            12150..12644
                     /locus_tag="KGS77_RS31010"
                     /old_locus_tag="KGS77_30790"
     CDS             12150..12644
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lassopeptide: PF13471"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020123203.1"
                     /locus_tag="KGS77_RS31010"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KGS77_30790"
                     /product="lasso peptide biosynthesis B2 protein"
                     /protein_id="WP_242586418.1"
                     /sec_met_domain="PF13471 (E-value: 1.1e-24, bitscore: 85.3,
                     seeds: 84, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTVPVVSELPVRLSRRRQITARCAVAAARALILLPPHRLGQVLRA
                     LRHGARPARADRTLSARQAVVSVSARCAGQGCLQRSVATALLCRLRGTWPDWCTGVRTR
                     PFRAHAWVEAQGAAVGESEDMALYHVTMSVRHPRTGPRQPRTGTSQPRTDPSQPRQEHR
                     P"
     gene            12641..13627
                     /locus_tag="KGS77_RS31015"
                     /old_locus_tag="KGS77_30795"
     CDS             12641..13627
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016469534.1"
                     /locus_tag="KGS77_RS31015"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KGS77_30795"
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="WP_242586419.1"
                     /transl_table=11
                     /translation="MSAGTASAPAVRTEELTKFYGTHEAVTALDLTVPAGITFGFLGPN
                     GAGKSTTIGMLTTVLRPTYGRAEVAGYDVARAPDRVRRRIGLVFQESTLDADLTAEENL
                     RFQADLYGVPRDRARRAVGELLELVDLAPRKDTPVRTFSGGMRRRLEIARGLLHTPRVL
                     FLDEPTTGLDPQTRTAIWEHLHRLRREQETTLFLTTHQLEEAENCDRIAVIDHGELVVQ
                     GSPAELKAVIGADLVTLRTGDDRAAAQAVGDRFGLDATTGPHGVELRTADGAAFVPRLC
                     AELAVPVHSVTVTPPTLDDVFLHYTGRTIREAEGGGPMLLPGPVMRR"
     gene            13631..14653
                     /locus_tag="KGS77_RS31020"
                     /old_locus_tag="KGS77_30800"
     CDS             13631..14653
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1065: ABC-2 type
                     transporter"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020123205.1"
                     /locus_tag="KGS77_RS31020"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KGS77_30800"
                     /product="ABC transporter permease"
                     /protein_id="WP_242586420.1"
                     /transl_table=11
                     /translation="MARTRTPAGTGEGRPGGGTAVTPADPADPTDPMSAVNPTNPTDPV
                     NLTKTPDGPNAPPPVRERGAEESRERPAAALARDLRTVRVLWRREMIRFGRNRLRIAMG
                     LLTPLMFLFILGTGLNAALGSGGTAFQDYRAYLFPGVLVMSVQAPALAVGSSIVWDRQA
                     GFLRQMLVAPVRRSALLAGTSLGGATSGACYGALVLALAGSVGIPYHPRLLLALLELAL
                     IAFAFTALGVVAAVCIKRIETFQIAVSLAMGPLLFLSGAMFAVGGLPGWLGIVVRLNPV
                     TYGVDALRRTLPGNLDLGGTAKGPQWGEWTPPVLLEAGGVLLLALFALAVATRRFSRAD
                     "
     gene            complement(14800..15651)
                     /locus_tag="KGS77_RS31025"
                     /old_locus_tag="KGS77_30805"
     CDS             complement(14800..15651)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019331101.1"
                     /locus_tag="KGS77_RS31025"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KGS77_30805"
                     /product="hypothetical protein"
                     /protein_id="WP_242586421.1"
                     /transl_table=11
                     /translation="MPREWGRRHVLRTALAATAAVGAGQTGWAATAAAGPASGAGTGAG
                     TGAGAATAAGRGSGPDLPPVPGMHGDRRANEMWYLLDQLTFYHPSQEVRDAYNAIGSYL
                     GGGIELPLRDRWLEMVRTPEYPRNFTAFVTPVKQPMEVLSRVQLHVYEETVYGPGDPRL
                     TAAFGYFGEGVLYDPRSEDPATPVHTMGYGPNGEPPIGYHVWYVYLRSMMFLGIARERW
                     ARIAPLIAFAWALQSLAKPAEGRVNPPLPRRMVAEQAVRRLPRGTRQLDQDFQSLPYPR
                     DL"
     misc_feature    15748..15763
                     /note="TFBS match to AfsQ1, Two-component system AfsQ1-Q2,
                     activator of antibiotic production, confidence: medium,
                     score: 17.11"
                     /tool="antismash"
     gene            complement(15869..18325)
                     /locus_tag="KGS77_RS31030"
                     /old_locus_tag="KGS77_30810"
     CDS             complement(15869..18325)
                     /GO_component="GO:0005829 - cytosol [Evidence IEA]"
                     /GO_function="GO:0003676 - nucleic acid binding [Evidence
                     IEA]"
                     /GO_function="GO:0003729 - mRNA binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006602031.1"
                     /locus_tag="KGS77_RS31030"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KGS77_30810"
                     /product="Tex family protein"
                     /protein_id="WP_242586422.1"
                     /transl_table=11
                     /translation="MTASTESIGSTGTTGSIEARIAEELGVRERQVKAAVELLDGGSTV
                     PFIARYRKEATEMLDDAQLRALEERLRYLRELEERRTAILESVRSQGKLDAALEARLRE
                     ADSKARLEDIYLPYKPKRRTKAQIAREAGLEPLAEGLLSDPSVEPAAAAAAFVDADKGV
                     ADPAAALEGARAILTEKFSEDADLIGELRERMWTHGQVVAKVREGKEEAGAKFADYFDF
                     AEPFTELPSHRVLAMLRGEKEEVLDLSMEPQAPSEAVEGPSAYERAIAHRFGITDRGRP
                     GDRWLLDTVRWAWRTRVLVHLGIDVRLRIRQAAEDEAVRVFASNLRDLLLAAPAGTRAT
                     MGLDPGFRTGVKVAVVDATGKVAATETIYPHVPQQKWDASLATLARLAREHGVELIAIG
                     NGTASRETDKLAADLIAAHPELKLTKVMVSEAGASVYSASAFASQELPELDVSLRGAVS
                     IARRLQDPLAELVKIDPKSIGVGQYQHDLSEVKLSRSLDAVVEDCVNGVGVDVNTASAP
                     LLSRVSGISSGLAENIVAHRDANGPFRARKALKDVPRLGPKAYEQCAGFLRIRDGEDPL
                     DASSVHPEAYPVVRRMVKAAGTEVASLIGNTTVLRALKPADFVDDSFGLPTVTDILQEL
                     EKPGRDPRPEFRTATFKEGVEKIGDLRPGMMLEGVVTNVAAFGAFVDIGVHQDGLVHVS
                     AMSKNFVKDPRDVVKSGDVVRVKVMDVDIPRKRISLTLRLEDEPGDGGERKERGERGRS
                     GERGERRGGAPRQRQGGGRAGDGRQGGDRQRGGDRRGGRDAAPANGAMADALRRAGLLG
                     KERDGR"
     misc_feature    complement(18357..18373)
                     /note="TFBS match to NtrC, Nitrogen regulatory protein C,
                     confidence: medium, score: 22.23"
                     /tool="antismash"
     misc_feature    18362..18374
                     /note="TFBS match to LuxO, Repressor of luminescence,
                     confidence: weak, score: 16.37"
                     /tool="antismash"
     gene            complement(18563..19435)
                     /locus_tag="KGS77_RS31035"
                     /old_locus_tag="KGS77_30815"
     CDS             complement(18563..19435)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003981471.1"
                     /locus_tag="KGS77_RS31035"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KGS77_30815"
                     /product="hypothetical protein"
                     /protein_id="WP_242586423.1"
                     /transl_table=11
                     /translation="MTFTTTLPERAGRRCHNVINPLHSSVYFAPEFPAELAGLGVQDPS
                     AAYFVGRAAAMGAVGPGTVTATFYNFSHDLIARHLPHTWSVVTPQDVLAARLRAADATL
                     RRLLGDAVVESPEMAEAAELALRAAQGCSRPARPLYAAHADLPVPDAPHLAFWHAATLL
                     REHRGDGHLMALLDAELDGLEALVTHTATGRGMSPKAVQRTRGWSATQWEAAKDRLLLR
                     GLLDEEGELTAAGTELRRSLEETTDRLDRGPYEYLGAEGVARLTELATAFTTAALAAGA
                     FPAEMFGKG"
     gene            19614..20609
                     /locus_tag="KGS77_RS31040"
                     /old_locus_tag="KGS77_30820"
     CDS             19614..20609
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1287: AraC family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019330366.1"
                     /locus_tag="KGS77_RS31040"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KGS77_30820"
                     /product="GlxA family transcriptional regulator"
                     /protein_id="WP_242586424.1"
                     /transl_table=11
                     /translation="MEQRDVLVVLFEGVQSLDVTGPVEVFTGASRCVPGSYRVRTATLD
                     GGPVRTSSDLTLAPDLSLADAGAPDILLMPGGRGTRAPDPRLVAWLREHAPHARRKVSV
                     CTGAFLFAAAGLLDGRRATTHWTRCAALAENFPAVRVDPDPIYVRDGDVATSAGVTAGI
                     DLALALVEEDLGRDTALAVARHLVVFLRRPGNQRQFSVQLAAQTAERRPLRDVQQWITE
                     NPAADLSVEALAQRASLSPRHFARAFRAEVGMTPGRYVDRVRIEAARRLLEDTADGVEE
                     ISRRCGYGTPESMRRAFVRTLGAAPAEYRRRFRTVPVGLPSAPLASTYRR"
     gene            20685..21323
                     /locus_tag="KGS77_RS31045"
                     /old_locus_tag="KGS77_30825"
     CDS             20685..21323
                     /EC_number="4.2.1.-"
                     /GO_function="GO:0016829 - lyase activity [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003981473.1"
                     /locus_tag="KGS77_RS31045"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KGS77_30825"
                     /product="DJ-1/PfpI family protein"
                     /protein_id="WP_242586427.1"
                     /transl_table=11
                     /translation="MQIAILLFDRFTTLDAVGPYETLARIPGAEVVLVGERTGPYRNEL
                     GTLGLVADAELSEVSAPDILVVPGGPGQNEQMEDGPLHEWIRAVDAGTTWTTSVCTGSL
                     ILAATGLLKGRRATSHWMALDLLATYGAEPTGERVVFDGKYVTAAGISSGIDMGLALVG
                     RVAGDFRAQCVQLGIEYDPQPPYNAGSPRTAPPEVTAALREHSRFFLKD"
ORIGIN
        1 catgctcgcg ggcgtcaacg accggcccgg cacccgcagg accggtgtgg tgcacatcgg
       61 gctgcccgcc ctcgcctccg cgctgggcat gctgacgggc gcctcgctgc gggcggcggg
      121 tgtgcagtgg ggcctgctcc cggcgctgtt cgtggtcggg ttcctctccg gtgcgggcag
      181 cgtcgccggg cccgtacggt ccaacgcggg cgtgcagatg ctggccgcca ccatcctggg
      241 cgcgggcatg ccgctgtccg gcgcgccctg gaccaaggct ctgtgtctgc tcgccgggtg
      301 cctgtggctc ctgctgctgc ggctggtgct gcacccgccc cgcccggccg gcgggccgct
      361 gagcggggag cgggccgccg tcgccaccgt cttcgacgcc ctcgcggacg cgctggaagc
      421 cgtcggcggg cccggcgcgg agcccgcccg gcgccgcctc accgccgcct tggaccgcgc
      481 cgacgaggcc ctgcggctgc gccggctgct gcgccggacg ccccgtacgg aggagcgcct
      541 gctcagggag cggctggccg ccgccacggc gctgtgcgag gccggcatcg ccctgctgtg
      601 ggaggcccgg ccgctgcccg cgcggaccgc cgagggcccg cgggccctgg cccggtccct
      661 gcgtaccggc gagccgccgg gccggctgcc gtccccgagg gccacctcgg ccgcccgcga
      721 agccttcgac cgtgccctcc tggacgccgc ggtcgtcttc gcccgcaccg ggcccgccgc
      781 cggggcgacc gccacggcaa cgggcccggc cccctcgaac ggctccgcac ccgctcccgc
      841 cggtactgcc accggcactc ccaccggcac ccccgccgac accgccaccg acgaggcagc
      901 acggtccggc cgtaccggac aggcggctgc gaccggacgg tccgaccgta ccgggcacac
      961 caccagcgcc gtacggaacg ccatacggaa cgccatgcgc ctgatgaggg cggtggtcag
     1021 cccccgcacc cgccccggcc ggcaggtgtt cgggcccgcc ggccgcgaat acggcctgcg
     1081 ggtcgccgtc tgcgtcgccg ccagcacggc cgtggccctc ctgctgcgcc ccgaccactg
     1141 gtactggctc cccgccaccg ccaccttcct cgtcaaaccg gacctgggtc cccttttctc
     1201 ccgtacggtc aaccgcttcg ccggcaccgc cgccggggtc ctggtcttcg ccggggcggg
     1261 cgcgctgctg ggcggggcct ggtggtggcc cgcgctggcg gccggggcgg gcggcgcgct
     1321 gctgccgttc gccacccgtc acttcgcgct ccagaccgtc gcgatcacgg tcatggtgct
     1381 gtcgttcgtc catgtcagcg gtgacccgca ggccgcgttc gagcggatcg tggacacgtc
     1441 catcgcctgc ggcatcgtgc tcgtcgtcgg ccatctgccc aggctggccg acccgcgccg
     1501 ccgtgtgggc cagcgggtca cggccgcgct gcgccgcacc gagagctatc tgcgtacggt
     1561 gctcgaaacc gggccggggc aggaccccgc ggcgcggctg ccgctgcgcc gggccgccta
     1621 ccgggcgctg ggggaggccc gggcggcggc cgagaccgcg gcggccgagc tgctcgccgt
     1681 ccgcgaccgc aaccccgact ggacggccgt cgtcaccgcc gcggaacgca tcgtcgacgc
     1741 ggcgaccgcg tgcgccgtac gcctggagca cggtgcgcgc cgcccgagcc ccgaggacgc
     1801 ccgccggctg tgccgggcgc tgtcctcgat ggccgacgcg ctggaggacc cccgccggcg
     1861 cggcgccggc gcggcgtccg ggcccgcccc cgcactgcgc cccgtaccgg actgcgccac
     1921 tctcaccgac gtggcggcgg aactggagcg cctgcggggg tacgcgggcg cggcctgagc
     1981 gttcggtggt ggcgcattcc gttccgtccg gaccgattga tccggccatg tccgggcaaa
     2041 gaccggacgc gatcggacag ggtcggtcac gatcccgtcg tacgacagaa aatgacagct
     2101 ctgtggagct gtttgtcgct taccgcacgt cgcaagcaca cacaggaacc gagcccgccc
     2161 ccctcgccgc accgggagca ctcctgcgcc cctcggcccc cgaacgtacc tgtgctcacc
     2221 tgcgcctcga ccggctcacc gcccccgccc gtccacggcg taccaggaca tgatgacgcg
     2281 aattgccact cccgggggag cgcggcgcgc atacgctcgc ggcaagagaa ctcgcacgca
     2341 gtggaccaag agaacgcgca cgacagtgga caacgggggc aagcgtgggg tgcttcgcgt
     2401 ggttgcgatc gtcgggaggg gacggagagg acaggagaga ccggcgaagc gccggtgagg
     2461 tgctgcaccg cgcgggcgcg taccgattac caccgacctg gcgggacctg gccgtcacgg
     2521 tcgtgctgct ctacggcgtg ttcacggtct tccccgcggg taccggactc ctcggccggc
     2581 agaccgccct ggacgacggc tcgcccgtgg tcggcccggt cgacgtcctc ctccagctcc
     2641 tcgtctccgc gatggccctg ccggtctaca tgggcctggc cgcacgctgc cgggagtccc
     2701 gctcgcccgc ctggcgcaga cgctgcgcgc tgctggccgg cgccgggttg ctgctgctca
     2761 ccgcggccgt accggtggtg ggagtggccg cactgtgttt cctgggcggt ggtgtgctgc
     2821 gggagcgcag ggcgctgggg cgcccccggc cggccgcgcc gccgcccgcc gaaccgggct
     2881 tggtgaccga ggcccggcag gaggagcgca gccggctccg gcgcgacctg cacgacggcc
     2941 tgggcccggc actggctgga atccggcttc aactggagac cgcccaggcc cggttgcagc
     3001 gggaaccgga cgcgcggcgg ctggtggccg ccgccgcggc acagaccgcg caggccgtac
     3061 aggaggtcca ccgggtgatc gacgggctgc gccccgccga cctggaggag gacgaactcc
     3121 ccggcgccct gcgcagactg gcgcgccgga tgcgcaacac ctcggtggcc atcgccgtcc
     3181 gtacccccga gcggcccgcc cggatcgcgc cggtgaccga ggtggccgcg taccgcatcg
     3241 ccgccgaggc cgtgaccaac gccatccggc acgccgacgc cgaccggatc gagatgcggc
     3301 tcaccacggg tgaggaaacc gtggtgctgg atgtcatcga cgacggcgtg ggactgcacc
     3361 cgggcagccc gcgccactac gcggtgggcg tgacgtccat ggcccggcgc gccgcggacg
     3421 tcggcggacg gtgtgtggtg gcctcccgcc ggggcccgag tccggggacc gtcgtccacg
     3481 ccgaactgcc ccggagcccg cggtgaccat acgggcgttc cttgtcgacg accatccgct
     3541 cttcctgaca ggggtgcggg tcgcgctcca ggacgcgggc gtggccgtgg ccggtgaggc
     3601 acacagcggc gaggaggcgc tgaagcagtt gcgtgcgacc ggtgcgcgca tcgacgtggt
     3661 cctggtggac gtccagctcc ccggctgttc gggcatcgag gtggcccgcg ccatcacctc
     3721 cggcggcgcg ccggagggcc accgtccgcg ggtgctgatg gtctccatgt cccaggacga
     3781 cgacgtggtc gtggcggcgc tgcgggccgg ggcgcacggc tacaccctca agagcgcccc
     3841 gagggaggaa ctgctgcggg ccgtacggat cgtggccgac ggcggcgcgg tgttcagccc
     3901 gtcggtggcc ggccggctgg ccacgtacgt ctccatgggg cgcgacctgc cgggccgcgc
     3961 ggccttcccc gaactgaccg accggcagcg ccagatcctc gatctgctcg cccgggggta
     4021 tgacaaccgg cgcatcgccc gggaactggt gctgtcggag aagacggtcc gcaaccacct
     4081 ctcccacgtg ttcacccggc tgcgggtcaa cgaccgtacg ctggcggcgg tacgggcccg
     4141 cgacgccgga ctgggaacct gaacggcgca gcgtaccccc ggcgccgaac cgggcgggta
     4201 tggcgaggtc ttcatcggac cgtaccgcgt cgggagcgtg ccgcgagcgc cgcacggccg
     4261 ccgttccggc cccggagaac gacaggaaca cgaccggccg gtcacggcat gatgccgcgg
     4321 atgaacacga tgggcgaggt gccggaccac ggtccccaaa aagcgccgga gcgtcttcgg
     4381 ccgccccgat ttccgcctgc tctggtgcgg cgagaccgtg agcgggctgg gcaacggcat
     4441 caccgtggtg ggcctgccgc tgatcgcggt ccaggtgctg gacgccggct ccaccgccgt
     4501 cggcctgatc tccgcggcgg tgtggctgcc ctggctgctg gtcggactgc cggtgggcgc
     4561 atgggtggac cggatgcgca aacggccact gatgatcgcg tgcgatctgg tggccgccac
     4621 ggcgctgctc agcattcccc tggccacgtg gcgcggcgcg ctcgccctcc cgcaggtgat
     4681 cgtcgtcgca ctggtctgtg gtacctcggc ggtgtgcttc aacaccgctt accacgccta
     4741 catccggatc gtgctcgacg gccgcgacct gctggagggc aacgccgaac tgcagggcgg
     4801 cgaggccgcc acgcaggtcg ccgggccggg ggtggccgga gcgctcaccc aggcgctcgg
     4861 cgcggtcgcc gggctcgtgg ccgacgcggt gacgttcctg gtctccgcgg tctgcctccg
     4921 gcggatccgg gcggtcgagc cggaccccgc tcccgacggg gaacgcgacc tcctgcggcg
     4981 gcagatcctc caagggctcc gcttcgtggg ccgggaccgg tacctgcggt ggatggtcac
     5041 ctggggtgcc gtgatcaaca tggcgctgat gggctgccag gcgggccagg tcgtgttcct
     5101 ggtacgtacc gtcgggctgg acccggccac ggtcgggctg ctgctgttcg tgacgggcgc
     5161 cctcgtcgtc gggaccggcg tttccgtggc cgatgtggtg gtcggcacct tccggcagac
     5221 ctactgcccg ccgcacatgc tcgggcgggt ggtggcgacg gccatgactg ccaaccacag
     5281 caccatcccg ctcgggtccc tgctcggcgg cgtgctcggt gacgcggtcg ggtgccgcag
     5341 gaccatgtgg atcatgacgg gtgtcatcgc gctctcctgg ctcgtcctgg ccgtgggccc
     5401 gctgcgtcac gagcgtgacc tgccgcggac ccgcgcaccg gaacaggtgc ggcgcagacg
     5461 ggaaggggag cggagcgccg cctgagcggg ctgcccggcc gggccggggc cgggtcagtc
     5521 cccggggcct tcgggccgca ttccggagcg tggacgggcc gcggtgacca ggcccgtctc
     5581 gtaggcggcg atgacgagtt gggcccggtc ccgggcgccg agcttgccca gcagatgccc
     5641 cacgtgtgtc ttgaccgtcg cggggctgac gtgcagatgg ccggcgatct cggcgttgga
     5701 caggccgcgg gcgatgagcg tgagcacctc gcgttcgcgg tcggtggtgc ccgccagttc
     5761 ccgggacggc cgctgggccg gctcgggccg gccggcgaac tccgcgatca gccggcgggt
     5821 cacgctcggc gccagcagcc cctcgccgga ggcgaccacc cggaccgcgg tgagcaggtc
     5881 ggcgggcggg gtgtccttga gcaggaagcc gctggccccg gcgcgcagcg ccccgtacac
     5941 atacgcgtcc aggtcgaaca tcgtcaggat gagcacgcgg gtggcggccg tggcgggcga
     6001 cccgcagatc gcccgggtcg cctcgatgcc gttcatctcc ggcatccgga cgtccatcag
     6061 caccacgtcc gggcgctcgc gggcggccag ttcggcggcc tgcgcgccgg tcgccgcctc
     6121 accgacgacg gtcagcccgg gctcggcctc cagcaggacg cggaaactgc cgcgcagcag
     6181 cgcctggtcg tcggcgacga gcacgcggat ctggtcgctc acactgcttc cttgtcggat
     6241 cgccggtccc cttcgccgga tgccccgccg ctttccccat cggcttcccc atcggtgtgg
     6301 ccgtcggttc tcccggcggg ccggacggtg gattcgtagg gtatacgggc ccgtacgcgg
     6361 tagccgccgt cggacagggg cccggcggtg aagctcccgc cgtacaccgc gacccgctcc
     6421 cgcatgccga tcaggccgtg gccgccgcag agttggccct cgcccgcctc gccgtccccc
     6481 aagggcgcgg cacgcctctc ggcgggcacg gcgcgtccct cgtcgcgcac ctcgatccgt
     6541 acgtcgcggc cgtcggccgt cacggccacc cggcagtgcg tcggagcggc gtgcctgacc
     6601 acgttcgtca gggcctcctg cactatccgg tagacggtca gcgccacccc gtccggcagc
     6661 gaggcgacgc cgcgcacctc ccgccggacg gtgatgcccg ccagtcgggc ccggtcgatg
     6721 agccggtcca ggtcggtggc cccgggtgcc ggggccaggc ccgcgtccgc gtcgccctcc
     6781 tccgtacgcc aggcgtccag cagataccgc atctcgcgca gcgcgccgcg gccgatgtcc
     6841 tcgatgaccc gcagcgcgtc gtacgcctcc tgcgggcggg cccgcccgac atggttggcc
     6901 accgcggcct tgaccgtgat cagccccatg ctgtgggtga cgatgtcgtg catctcgcgg
     6961 gcgatgcgca ggcgctcctc ggccaccgcc agctcggcga actcccgtgc cgcgcgctgc
     7021 gcgtaggcac gccggtcccg caccgcccgc cccacggtcc acgccccgcc cagcacggca
     7081 cagcccacca gcgcggtgcc cggggcctgg ttccacatgc cgcgggtgcc cgcgagggtg
     7141 cacaggagga gcagggccgt gctcaggccc ccgatgaccc gggtcggcac ggaccggggc
     7201 cgggacccgg tgagcgcgac ggtgtagagc gcgaacgccg cggcggtgaa ggggtcacgt
     7261 acggcgccca gggccaggcc caggacggac agcgtcagga cgagggcgaa gacgggcagc
     7321 ggccacagcc ggcgcaccgc gcacggcagg ccggtccccg cggcgatcag gcacaccgcc
     7381 cacaaaggca ggtccggcgc ggcgtcggcg gggctccccc gcccgtacag aagcatcagt
     7441 ggaacggtcg cgaagagcag cgccgccagc ccgtcgagca cgaccagttg gccgcggccc
     7501 agcggctgga ccagcaccgg gcgcggggcg ggttcggaca tgccccgagc gtatccggcc
     7561 cggcccgcgc ccgcgtccgc ccacgggtgg tcatccgagg ggctgatccc gtacgccgcg
     7621 ggcggccgtc cgtcagcccg ggggccgagg ccggaactcg ccggacgctc cgacgcgccg
     7681 cggtgcccgg cggcgggagc cttgcggggt gatcgatgtc aagaacctca ccaaacgcta
     7741 cgggcggacc gtggccgtgg acgggctgtc cttccaggtg ctgccgggcc gggtaaccgg
     7801 cttcctgggg cccaatggcg cgggcaagtc caccaccatg cgcgtcatgc tgggtctgga
     7861 ccggccggat caggggcagg tcctgatcga cggccggcgt tacgacgggc tgcgggagcc
     7921 gctgcggcac atcggcgcgc tgctggaggc caagtccgtg cacggcggcc ggagcgccta
     7981 ccaccacctg ctgtggctcg cccgtaccaa ccggatcccc cggcggcgca tcgccgaggt
     8041 catcgagctg gtcgggctgg agagcgcggc cggcaagcgc gccggaggct tctcgctggg
     8101 catgagccag cggctgggca tcgccgcggc cctcctgggg gacccgcgga tcctgctgct
     8161 ggacgagccg gtcaacggac tggaccccga aggcatcctg tggatacgga acctgatgaa
     8221 gcaactggcg ggggaggggc gcaccgtctt cgtctccagc cacctcatga gtgagatggc
     8281 gatcaccgcc gaccacctca tcgtcatcgg gcagggccgg ctgctggccg acaccagcat
     8341 gagttccttc atcgagcgca actcccgtac gagcgtccgg gtccgtaccc ccgaccccga
     8401 gcggatgcac aaggtgctca ccgcgcgggg catcgacgtc gagcgggcgg cggacggcac
     8461 gctggaagcg gtgggggccg ctccctcgga ggtcggcgaa ctggccgccg ccaacgggct
     8521 gaccgtccac gaggtcagcg cgcggaccgc ctcgctggag gaggcgttca tgcggctgac
     8581 ggcaccggcc gtggagtacc acgccgggcc cgcccgggag gggaaagcac atgagcacgg
     8641 cagccgccag ggcggtcctc tccgccgaac tgatcaagat ccgtacggtg cgctccaccc
     8701 tgtggacgcc cctgctgacg ttcgtcatca gcgtgggcat cagcctggtc ttcgccatgg
     8761 ccttccacga ccgcttctcc gccatgccac cggaccagca gcgctccttc gacccggtca
     8821 tggccgggtt ctacggcctg accttcggcc agctcatgct ggtggcgttc ggcgtgctga
     8881 ccgtcagctc cgagtacacc accggaatga tccgcgcctc gctggccgcg gtaccccgcc
     8941 ggggagcgtt ctacgccgcc aagacactgg ccggcacgct cgtggccgcc gcggtatccg
     9001 tcctgaccac cgtcgtcacg ttcttcaccg cacagagcac cctcggcccg cacggcgtct
     9061 ccctcgggga ccccggggtg ctgcgcgcga cgctcggcac ctgcctctac atgacgctga
     9121 tctgtgcctt ctccataggc gtggccacca tgctgcgcag ctccgtcctc tccctgggca
     9181 tattgatccc cctgttcttc atcgtctccc cggtcctggc caacatcccg gccctgagag
     9241 cggtcgccca gtacctgccc gaccaggcgg gactgcagat catgcgggtg gtcccgagga
     9301 ccaccgacct cggccatgac atgggcccgc tggccggact gttggtcctg gtgggctgga
     9361 ccgccgcgtc cctcctcggc ggatacctcc tgctgcgccg ccgcgacgcc tgacccctga
     9421 gcccccgggt cccggtctcc ccctccggga cccgggatcg gggcatgtgg cccgggaccg
     9481 gggacgggac ccggacggga cgggacgctc atgtgcccgg ggcgacgggc cgcttacctt
     9541 cgaggagttc acggcgcacg gaccgctgcc ggacctcgcg gcggcggtcc gtgcccacaa
     9601 cccatatcaa gggatggtga gcaccatggc ggaattcgag acggtatatg agccccccac
     9661 gctggtcgag atcggcgact tcgccgacct gaccctcggc atctggggct gcccgcacga
     9721 ctggttcggt ctcagcacgc cgttcgcctg ctgatacccg ggtgcggggg ccgatgccac
     9781 gcggcccccg caccgcccgg gcatccgcct ccccgacctc acagggcagt acagccggcg
     9841 cgcagcatct ccgctgaggc gcggcaccct tcggtgcggg ctgtgtaacg ggggcccgcg
     9901 tccgtcacgt gcgacgggcg cgcgagaacg tacggaagat ccaccacgcc ccgccggccg
     9961 aagccgaaga gccctgagcc ccgagcccga agaaggagcc atggaatttc tggtgctccc
    10021 ggacagcccg gcggccgacg gcatcgccga ggcggcccgg caggccgcgg gccgtgatgc
    10081 cgcgcggtct ccggcccgga ctccgtcccc ggcccggacc ccgtccctga cccggaccct
    10141 cacccatgcc tccgggcggc cctggctgct gggtgactgg acggatgagg aactgacgct
    10201 ggtcaccgcg ggcccccgcc ggctggcgct gctcggcacc acccgcctgg acgccggcac
    10261 cgcgcggcgt gcccttgccg ccgcgcggac cccgcacgac ctggacgccg tggcccgcac
    10321 cctgccgggc gtcttccacc tggcggcctc gatggacggc cggacccgta cgcagggcac
    10381 cctgtccacc taccggcagg tcttccacac gcgggtcgcg ggcgtcacgg tggccgccgc
    10441 ctccccggcg cccctgaccg ccctcaccgg ggcgcgtacc gacgacgcca ccctcgcggt
    10501 acggctgctg gccccgctga tcccctggcc gctgagcatg cgctccgtct ggaccgggat
    10561 cgatcagctc ccgctgggca gttggctgca caccgacgcg gacgggcgct cgcgcaccgt
    10621 gcgctggtgg cagccgcccg agccggacgc gacaccgagg caggcggcgc aggcggtgcg
    10681 cgcggcgctg ctggacgccc tgtcggtacg ggccggccgg cacggcaccc tcagcgccga
    10741 cctgtccggc ggcatggact ccaccagcct gtgcttcctg gccgacacct gcggtgccga
    10801 cctgatcacc caccactgga agccgctgga cccggccaac gacgacgcgc actgggccgc
    10861 acaggccgcc gcgcacctgc cgcgtgcccg ccaccacgtc gtaccggcgc gctccggccc
    10921 gacctggtac gaggccccgc cgcgccccga cgaggcccgc gccgccaccg agggcccctt
    10981 cacctggaac cgcaaccggc tgcacatgga acaggtcgcc cgtaccgtcg cggccgacgg
    11041 ctccggcctg catctgatcg gcgtcggcgg cgacgagctg ttcatcacgc tgcccaccta
    11101 cctgtggtcg ctggcgcgcg cccacccgct gcgcagcctg cccgtcgtcc accgctgccg
    11161 ggccgccaac cgctggccgc tgcgcgccac cgtcaaagaa ctcctgcact ccggcacctt
    11221 cgcccgctcg ctggccgtca ccgcggacac cctggccgac ccgctgcgcc gccccaccga
    11281 cgtacgcctg cgctggggag ccgaaccgcg gatgccggcc tgggccaccc gcgacgccgt
    11341 cgaggcggtg cgctcgctgc tgtacgaggg cgccgcagcc gggcagccgc cgctggcacc
    11401 gggccgcgcc cagcaccaga tcctggagaa cgtgctgttc ggcggcgcca acgtgcggca
    11461 gatggacgcg gccatggccc ggttcggtgt gcgctggcag gcgccgttcc tggacgaccg
    11521 ggtggtcgag gcggcgctga ccatccggat cgaggaccgc ttccggcgcg gcagctacaa
    11581 gccggtgctg gccgcggcca tgcgcggcat cgtcccgcag ccggtgctgg accgccgcac
    11641 caaaggggac ttcggtgccg aggcgtacga agggctgcag cgcaaccagc gggcgctgct
    11701 ggagtggtgc caggacctgc ggctggccgc gcgggggctg gtcgacgccc ccgcgctgcg
    11761 cgccgcgctg ctgcggcccg gccaggagac ctaccagctc gccccgtacg agcacaccct
    11821 cgcctgcgag agctggctgc gttcgcccgc cggggcgccc gccccggccg tcctcgcgac
    11881 aggagaccca cgatgaccct caccctgccc tcccacgtca gcgccaccga cgtggaggac
    11941 gaactggtcc tgctcaacga gcgggacggc cgctactggc acctgaaccg gaccggcgcg
    12001 aagatcctgc ggctgctgct ggccggccac tcgcccgaag agagcgcccg cctgctgacc
    12061 cgcgactgcc cggacgccgc cgagcgcgcc ctggccgacg tacgggccct gctggagtcg
    12121 ctgcgcgcct cgcgtctggt caagccgtca tgaccgtccc ggtcgtctcc gaactgcccg
    12181 tacggctgag ccggcggcgg cagatcaccg cccggtgcgc cgtggcagcg gcccgtgccc
    12241 tgatcctgct cccgccgcac cgcctgggac aggtgctgcg cgccctgcgc cacggcgccc
    12301 gcccggcccg cgcggaccgg acgctgagcg cccggcaggc cgtggtctcg gtcagcgccc
    12361 gctgcgccgg acagggctgt ctgcagcggt cggtggccac ggcgctgctg tgccggctgc
    12421 gcggcacctg gcccgactgg tgcacgggcg tgcggacccg gcccttccgc gcccacgcgt
    12481 gggtggaggc gcagggcgcg gcggtcggcg agagcgagga catggccctc taccacgtca
    12541 ccatgagcgt gcggcacccg cgtacgggcc cgcggcagcc tcgtacgggc acgtcacagc
    12601 cccgtacgga cccatcgcag ccgcgtcagg agcaccgccc atgagcgccg gcaccgcgag
    12661 cgccccggcc gtccgcaccg aggaactgac caagttctac ggtacccacg aagccgtcac
    12721 cgcactggac ctgaccgtgc ccgcgggcat caccttcggc ttcctcggcc ccaacggcgc
    12781 gggcaagagc accaccatcg gcatgctgac gacggtgctg cgccccacct acggccgggc
    12841 cgaggtggcc gggtacgacg tggcgcgcgc acccgaccgg gtgcgccgcc ggatcgggct
    12901 ggtcttccag gagtccaccc tggacgcgga cctgaccgcc gaggagaacc tgcgcttcca
    12961 ggccgacctg tacggcgtcc ccagggaccg ggcccgccgg gccgtcggcg aactgctgga
    13021 actcgtcgac ctggcgccgc gcaaggacac cccggtccgt acgttctccg gcggcatgcg
    13081 acggcggctg gagatcgccc gcggcctgct gcacaccccg cgcgtgctgt tcctggacga
    13141 acccaccacc ggcctggacc cgcagacccg tacggcgatc tgggagcatc tgcaccggct
    13201 gcgccgcgag caggagacca ccctgttcct gacgacgcat cagctcgaag aggccgagaa
    13261 ctgcgaccgg atcgccgtca tcgaccacgg cgaactcgtc gtccagggct ccccggcgga
    13321 gctgaaggcg gtgatcggcg ccgatctggt caccctgcgc accggcgacg accgggcggc
    13381 ggcacaggcg gtgggcgacc gcttcggcct ggacgccacc accggcccgc acggggtcga
    13441 actgcgtacg gcggacgggg cggccttcgt cccgcgactg tgcgccgaac tcgccgtacc
    13501 cgtccactcg gtgaccgtga cgccgcccac gctggacgac gtcttcctgc actacaccgg
    13561 ccgcacgatc cgggaggccg agggcggcgg gccgatgctg ctcccgggcc cggtgatgag
    13621 gaggtagagc atggcccgca cccgaacgcc ggccgggacc ggggagggac ggccgggcgg
    13681 cggcacggcc gtgaccccgg cggacccggc ggacccgacg gacccgatga gcgcggtgaa
    13741 tccgacgaac ccgacggacc cggtgaacct gacgaaaacg ccggacgggc cgaacgcccc
    13801 gcccccggtc cgcgagcgcg gcgcggagga aagccgggag cgtccggccg ccgccctcgc
    13861 ccgggacctg cggaccgtac gtgtcctgtg gcggcgggag atgatcaggt tcgggcggaa
    13921 ccggctgcgg atcgccatgg gactgctgac cccgctgatg ttcctgttca tcctgggcac
    13981 cgggctgaac gcggcgctgg gcagcggcgg tacggccttc caggactacc gcgcctacct
    14041 cttccccggc gtcctggtga tgtccgtaca ggcccccgcc ctggccgtcg ggtcctcgat
    14101 cgtctgggac cgccaggcgg gattcctgcg ccagatgctg gtggcgcccg tgcgccgcag
    14161 tgcgctgctg gccggaacgt ccctgggcgg cgccacctcg ggcgcctgct acggcgcgct
    14221 ggtcctggcg ctggccggct ccgtcggcat cccctaccac ccgcgtctgc tgctggccct
    14281 gctcgaactc gcgctgatcg ccttcgcatt caccgccctg ggcgtggtcg cggcggtgtg
    14341 catcaagcgg atcgagacct tccagatcgc ggtgagcctg gccatgggac cgttgctgtt
    14401 cctgtccggc gcgatgttcg cggtcggcgg gctgcccggc tggctgggca tcgtggtccg
    14461 gctcaacccg gtcacgtacg gggtggacgc gctgcgccgt acgctgccgg gcaacctgga
    14521 cctgggcggt acggcgaagg ggccgcagtg gggcgagtgg accccgccgg tcctgctgga
    14581 ggcgggcggg gtgctgctgc tggccctgtt cgccctggcg gtggcgaccc gccgcttctc
    14641 gcgcgccgac tgaccgggcc gccggccggc cgggccatcg accgacccgg ccgccgaccg
    14701 accggcccgc cggggccggg gcacggaaag cgcggggagc cggcggccgt cgggcggtga
    14761 cgccggctcc ccgcgtgaac tacaggtccc tacaggcccc tacaggtccc tgggataggg
    14821 cagcgactgg aagtcctggt cgagctgccg ggtgccgcgg ggcagccggc gtacggcctg
    14881 ctcggccacc atccgccggg gcagcggcgg attgacccgc ccctcggcgg gtttggccag
    14941 cgactgcagg gcccacgcga aggcgatcag cggcgcgatc cgcgcccagc gttcccgcgc
    15001 gatgcccagg aacatcatcg accgcaggta cacgtaccag acgtggtagc cgatgggcgg
    15061 ctcgccgttg gggccgtagc ccatggtgtg tacgggggtg gccgggtcct cgctgcgcgg
    15121 gtcgtagagc acgccctcgc cgaagtaccc gaacgccgcc gtcagacgcg ggtcgcccgg
    15181 gccgtagacc gtctcctcgt agacgtgcaa ctggacccgc gagagcacct ccatgggctg
    15241 cttgaccggt gtcacgaacg cggtgaagtt gcgcgggtac tcaggcgtcc gcaccatctc
    15301 cagccacctg tcgcgcagcg gcagttcgat gccgccgccc aggtagctgc cgatcgcgtt
    15361 gtaggcgtcc cgaacttcct gggaggggtg gtagaaggtc aactggtcga gcaggtacca
    15421 catctcgttg gctctgcggt cgccgtgcat gcccgggacc ggtggcaggt ccgggccgct
    15481 gccacggccg gcggctgttg cggcaccggc gcccgtgccg gcccccgtac cggcgccgga
    15541 ggcggggccg gctgccgcgg tggcggccca gcccgtctgt ccggcgccca cggccgccgt
    15601 ggcggcgagc gcggtacgca gtacgtgccg tcggccccat tctcgcggca tggttcttcc
    15661 ccttacgtcg ggaacatcac cacgggcccc gtggccccgg tcgccaacac cgtaggaggt
    15721 cccgtgtccc gggcgcttgg gcgtacggtc acgcccttgt cccggcccgt gtcccggccg
    15781 cacccggggc gaggggccgg tggaggggag ccgcgaggcg gggtacacga aggggcggcc
    15841 cgccgtccgg ccggccgccc cttcgccgtc agcgcccgtc gcgctccttg cccaaaaggc
    15901 ccgcccggcg cagcgcgtcg gccatcgcgc cgttggccgg cgcggcgtcc cggccgcccc
    15961 ggcggtcccc gccccgctgc cggtcaccgc cctgccggcc gtcgcccgcc cggccgccgc
    16021 cctggcgctg ccggggcgca ccgccccgcc gctcgccgcg ctcgccggac ctgccccgct
    16081 cgcccctctc cttgcgctcg ccgccgtcgc ccggctcgtc ctccagccgc agcgtcagcg
    16141 agatccgctt gcgcgggatg tcgacgtcca tgaccttgac ccgtacgacg tccccggact
    16201 tcaccacgtc ccgcgggtcc ttgacgaagt tcttggacat cgcggagaca tggaccaggc
    16261 cgtcctggtg gaccccgatg tccacgaacg ccccgaaggc ggcgacattg gtcaccacac
    16321 cctccagcat catccccggc cgcaggtcac cgatcttctc cacgccctcc ttgaaggtgg
    16381 ccgtcctgaa ctccggccgc gggtcgcgcc ccggcttctc cagctcctgg aggatgtcgg
    16441 tgaccgtcgg cagtccgaag gagtcgtcga cgaagtcggc gggcttcagg gcgcgcagca
    16501 ccgtcgtgtt gccgatcagc gaggcgacct cggtaccggc cgccttcacc atccggcgca
    16561 ccaccgggta cgcctccggg tgcacgctgg aggcgtccag cgggtcctca ccgtcgcgga
    16621 tgcgcaggaa gcccgcgcac tgctcgtacg ccttggggcc cagccgcggc acgtccttga
    16681 gggccttgcg ggcgcggaag gggccgttgg cgtcccggtg ggcgacgatg ttctcggcca
    16741 gcccggagct gatccccgac acccgcgaca gaagcggcgc ggaggcggtg ttgacgtcca
    16801 ccccgacccc gttgacgcag tcctcgacca cggcgtccag ggaccgcgag agcttcacct
    16861 cggacaggtc gtgctggtat tggcccaccc cgatcgactt ggggtcgatc ttgacgagtt
    16921 cggccagcgg atcctggagc cggcgcgcga tggacaccgc gccccgcagc gacacgtcca
    16981 gctccggcag ctcctgggag gcgaaggcgg aggcggagta caccgaggcg cccgcctcgg
    17041 agaccatcac cttcgtcagc ttcagctccg ggtgcgccgc gatcaggtcg gccgccagct
    17101 tgtcggtctc ccgggacgcc gtaccgttcc cgatcgcgat cagctcgacg ccgtgctcgc
    17161 gcgcgagacg ggccagcgtc gccagggacg cgtcccactt ctgctgcggc acatgcgggt
    17221 agatcgtctc ggtggcggcc accttgccgg tcgcgtccac cacggcgacc ttgacgcccg
    17281 tacggaaacc ggggtccagg cccatcgtcg cgcgggtgcc ggccggcgcc gccagcagca
    17341 ggtcgcgcag gttggacgcg aagacgcgta cggcctcgtc ctcggcggcc tgccggatgc
    17401 gcagccgcac atcgatgccg aggtggacca gtacgcgggt acgccaggcc cagcgcacgg
    17461 tgtccagcag ccaccggtcg cccggccggc cgcggtcggt gatcccgaag cggtgggcga
    17521 tggcccgctc gtacgcgctg gggccctcga cggcctccga cggcgcctgc ggctccatcg
    17581 agaggtccag gacctcctcc ttctcgccgc gcagcatcgc cagcacccgg tgcgagggca
    17641 gctcggtgaa cggctcggcg aagtcgaagt agtccgcgaa cttcgcgccc gcctcctcct
    17701 tgccctcgcg caccttggcc acgacctgcc cgtgcgtcca catgcgctcg cgcagctcac
    17761 cgatcaggtc cgcgtcctcg ctgaacttct cggtgaggat cgcccgcgcg ccttccaggg
    17821 cggcggccgg gtcggcgacg cccttgtccg cgtccacgaa cgccgccgcc gcggcggccg
    17881 gctccacgga cgggtcgctc agcaggccct cggccaacgg ctccaggccc gcctcccgcg
    17941 cgatctgcgc cttcgtccgc cgcttgggct tgtagggcag gtagatgtcc tccagccggg
    18001 ccttggagtc cgcctcgcgc agccgcgcct ccagggcggc gtccagcttc ccctgggacc
    18061 gtacggactc caggatcgcg gtgcgccgct cctccagctc ccgcagatag cgcagccgct
    18121 cctcaagggc gcgcaactgc gcgtcgtcga gcatctcggt cgcttccttg cggtagcggg
    18181 cgatgaacgg cacggtcgag ccgccgtcga gcagttcgac ggcggccttc acctgccgtt
    18241 ctctgacgcc gagctcctcg gcgatcctcg cttcgatgga tccggtggtt cctgtggacc
    18301 cgatggactc ggtggatgcc gtcacgttga tcctgacccg ccttccagcg cttgcttgag
    18361 cctgcattgt gcaggttggc gggccgggct gtcgcgtgcc gccgtccgga gcggcgaggt
    18421 gtgagaagcg gcactcgccc gcggccggcg ggcccactcc gggacgccgc gccggacagg
    18481 cgggccggag aggcgggccg gcagctcccg gggcggccgg ggccaaacct tccgggaccg
    18541 gcgcgcccgg ccgcacaggc gctcagccct tgccgaacat ttccgccggg aaggcccccg
    18601 ccgcgagcgc ggccgtggtg aaggcggtcg ccagctcggt gagccgggcc acgccctcgg
    18661 cgcccaggta ctcgtacggg ccccggtcca gccggtccgt ggtctcctcc aggctccggc
    18721 gcagctcggt ccccgccgcc gtcaactcgc cctcctcgtc cagcagaccg cgcagcagca
    18781 gccggtcctt ggccgcctcc cactgcgtcg cggaccagcc acgggtccgc tgtacggcct
    18841 tcgggctcat gccgcggccg gtggcggtgt gggtcaccag cgcctccagc ccgtccagtt
    18901 ccgcgtccag cagcgccatc aggtgcccgt cgccgcggtg ttcgcgcagc agcgtggccg
    18961 cgtgccagaa cgcgagatgc ggggcatcgg gcaccggcag gtcggcgtgg gccgcataca
    19021 gcggccgggc gggccgggag cagccctgcg ccgcgcgcag cgccagttcg gccgcctcgg
    19081 ccatttccgg gctttccacg acggcgtccc cgagcagccg gcgcaaggtg gcgtcggcgg
    19141 cccgcagccg tgcggccagc acgtcctggg gcgtgaccac cgaccaggta tggggcaggt
    19201 ggcgggctat caggtcgtgg ctgaagttgt agaaggtggc ggtgacggtg cccgggccca
    19261 ccgcgcccat ggccgcggcc cggccgacga agtaggcggc actggggtcc tggacgccga
    19321 gcccggccag ctcggccggg aactccggcg cgaagtagac cgacgagtga aggggattga
    19381 tcacgttgtg acagcggcgg ccggcgcgct cgggaagcgt ggtcgtgaag gtcatgcccg
    19441 gcaggttacc gacccgtcgg tatggccgtg agagcaggtc cggcccactc tgcgtacgat
    19501 ccggccgcgc acggtcgccc ggggtcacgg tcgcatgccc atggccgtaa aggtggggtt
    19561 ttcgtcattg ctgtcaattg ccgccgggac tgagcgccga ccaggatgac ggcatggaac
    19621 agcgcgacgt gctggtcgtc ctcttcgagg gcgtccagag tcttgatgtg accggcccgg
    19681 tcgaggtgtt cacgggggcc tcgcggtgcg tccccggctc ctaccgggtc cgtaccgcca
    19741 cccttgacgg cggcccggtc cgtacctcca gcgacctgac cctggccccg gacctctcgc
    19801 tggcggacgc cggggcgccg gacatcctcc tgatgccggg cgggcgcggc acccgcgccc
    19861 cggacccgcg gctggtcgcc tggctgcgcg agcacgcgcc gcacgcccgg cgcaaggtgt
    19921 cggtgtgcac cggggcgttc ctgttcgccg cggccggact gctggacgga cggcgcgcta
    19981 cgacccactg gacgcgctgt gcggccctgg ccgagaactt ccccgccgtg cgcgtcgacc
    20041 cggacccgat ctacgtacgg gacggcgacg tggccacctc cgcgggcgtc acggccggca
    20101 tcgacctggc cctggccctg gtggaggagg acctgggccg ggacacggcc ctggccgtcg
    20161 cccgtcacct cgtggtcttc ctgcgccggc ccggcaacca gcggcagttc tccgtccagc
    20221 tcgccgcgca gaccgccgaa cgccgcccgc tgcgcgacgt acagcagtgg atcaccgaga
    20281 acccggccgc cgacctgtcc gtcgaggccc tggcacagcg cgcgagcctc tcgccgcgcc
    20341 acttcgcccg tgcctttcgc gcggaggtcg gcatgacgcc gggccgctac gtcgaccggg
    20401 tacgtatcga ggccgcccgc cgcctcctgg aggacaccgc cgacggcgtc gaggagatct
    20461 cccgccgctg cggctacggc acgccggaat cgatgcgccg ggcgttcgta cggaccctgg
    20521 gcgcggcgcc cgccgagtac cgccggcgct tccggaccgt accggtgggg ctgccgtccg
    20581 ctccgctcgc ctccacgtac cggcgctgac cgctttcccg accgtacctt ccgtcccttc
    20641 cgtctcttcc gtttctctcg tccctctgat cgacaggagt taccgtgcag atcgcgatcc
    20701 tgctcttcga ccgcttcacg actctggacg ccgtgggccc gtacgaaacc ctcgcccgca
    20761 tccccggcgc cgaggtggtc ctggtgggcg agcgcaccgg accgtaccgc aacgaactgg
    20821 gcacgctggg gctggtcgcc gacgccgagc tgtccgaggt gagcgccccg gacatcctcg
    20881 tcgtgcccgg cggccccggg cagaacgagc agatggagga cggcccgctg cacgagtgga
    20941 tccgcgccgt ggacgccggc accacctgga ccacctccgt gtgcaccggc tcgctgatcc
    21001 tggccgccac gggcctgctc aagggccgcc gcgccacctc ccactggatg gcgctggacc
    21061 tgctggccac ctacggcgcc gagccgaccg gcgaacgcgt cgtcttcgac ggcaagtacg
    21121 tcaccgcggc cggtatctcc tccggcatcg acatgggtct ggccctggtg gggcgggtgg
    21181 ccggcgactt ccgcgcccag tgcgtccagc tcggcatcga gtacgacccg cagccgccgt
    21241 acaacgcggg ctcgccgcgg accgctcccc ccgaggtgac ggcggcgctg cgggagcaca
    21301 gccgcttctt cctgaaggac tgacacctca gtccgaaggg ccgcccccgc cggccccgct
    21361 gcctccgccg gacccgccgc ccccaccggc cccgctgcct ccgccgctcc cgggcgcgcc
    21421 ctcgctgttc ccgggcgcgc cctcgcccgg cgcgtccagc tcctcctgcc acaacagctc
    21481 cgtcagccgc ccgatcccgg cggccagatg gcgccggtag gtcgtcatcg gcagccgcag
    21541 cagctcggcg gcgcgcgcct gcgtaccggc cggccgcaga taggtgtggt gcagcgcccg
    21601 gaagccgcgc cggtcctgcg gggacgcctc cagcgcggcg gctgccgccc gtaccgcctc
    21661 ccgcagggcc gtggcccgct cccgcggccc ggcccgccgc gcacaccgcg ccgtgaccag
    21721 ccgggtcccc agcagcggcg agtcccgcag cccgtccgcc cgggccagcc cgcgcagcgc
    21781 ctcccgtacg gcgtgtgcga acgcctcccg gtccaggacg cgcagcggct ccggggcggg
    21841 tgggggcggc acggcgagcg ggtcctgggc ccgttcgcgt tcgatgagca tcgtcagcca
    21901 cgccggaccc ggcacccgcc gccagtcgtg gacgaacatc ccgaaccggc gcccgcccga
    21961 ggtgaagtcg gccgcgggca gccgtgcgaa gtcgacatag gcacagcccg cctcccagaa
    22021 ctccgggtcg gcgaacggca gcagcgtcag cgcgggccgg tgcccggtca ggtagtggtg
    22081 ggtcagccgc agtgtgatca gggtctgaac gggcgagacc gcctggtact cgtcgcggct
    22141 catccagaac cgcaccagca gcgccgtctc gccctcccgc agctccccgt ggcgcgccag
    22201 ccagtcgcag gccgtgcgga ccgccgggtc cgccggcgcc cccggcggct cggtgccggt
    22261 cagctcgatc agcgtgtaga accccgcggc caccccgtcg gggccccgta cggtgtgggt
    22321 gcgcgcctgg gggagcaccg accagtcctg taccagccgc gccgccgcgc tcccctcgtg
    22381 gatcgcggcg atcgcacacg cctggatcag ctcgccgccg ctcaccggca gcggcgagac
    22441 gctcagccgg tccaggtggg ccgcgcccgc cgcgccgcgc gtcaccgggt ccagcagcgg
    22501 cccgaccacc gggctgtccc ggtgcagata ggcgaagtcc gccaggaccg cgcgctgccg
    22561 ggcccggtcg tcgtcctcgg tgaacagccg ctggtagtac gcgccggccc ggcggtgcag
    22621 cagcgcccgc cgctcggggt gacg
//
