LOCUS       NZ_CP074380            21107 bp    DNA     linear   CON 27-MAY-2024
DEFINITION  Streptomyces sp. MST-110588 chromosome, complete genome.
ACCESSION   NZ_CP074380
VERSION     NZ_CP074380.1
KEYWORDS    RefSeq.
SOURCE      Streptomyces sp. MST-110588
  ORGANISM  Streptomyces sp. MST-110588
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1  (bases 1 to 7915503)
  AUTHORS   Booth,T.J., Bozhueyuek,K.A.J., Liston,J.D., Lacey,E. and
            Wilkinson,B.
  TITLE     Bifurcation drives the evolution of assembly-line biosynthesis
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 7915503)
  AUTHORS   Booth,T.J., Bozhueyuek,K.A.J., Liston,J.D., Lacey,E. and
            Wilkinson,B.
  TITLE     Direct Submission
  JOURNAL   Submitted (10-MAY-2021) Molecular Microbiology, John Innes Centre,
            John Innes Centre, Norwich, Not US or Canada NR4, United Kingdom
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: 28-FEB-2016
            Assembly Method                   :: HGAP v. 3.0
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 25.0x
            Sequencing Technology             :: PacBio RSII
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_022695595.1-RS_2024_05_27
            Annotation Date                   :: 05/27/2024 05:38:09
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 6,918
            CDSs (total)                      :: 6,828
            Genes (coding)                    :: 6,327
            CDSs (with protein)               :: 6,327
            Genes (RNA)                       :: 90
            rRNAs                             :: 7, 7, 7 (5S, 16S, 23S)
            complete rRNAs                    :: 7, 7, 7 (5S, 16S, 23S)
            tRNAs                             :: 66
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 501
            CDSs (without protein)            :: 501
            Pseudo Genes (ambiguous residues) :: 0 of 501
            Pseudo Genes (frameshifted)       :: 350 of 501
            Pseudo Genes (incomplete)         :: 185 of 501
            Pseudo Genes (internal stop)      :: 14 of 501
            Pseudo Genes (multiple problems)  :: 45 of 501
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 12:56:23
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 6190374
            Orig. end                         :: 6211481
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP074380.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            Bacteria and source DNA available from Barrie Wilkinson, John Innes
            Centre, Norwich.
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..21107
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="indole"
                     /region_number="25"
                     /rules="(indsynth or dmat or indole_PTase)"
                     /tool="antismash"
     cand_cluster    1..21107
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(indsynth or dmat or indole_PTase)"
                     /kind="single"
                     /product="indole"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..21107
                     /aStool="rule-based-clusters"
                     /category="other"
                     /contig_edge="False"
                     /core_location="[10000:11107](+)"
                     /cutoff="20000"
                     /detection_rule="(indsynth or dmat or indole_PTase)"
                     /neighbourhood="10000"
                     /product="indole"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..11107
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(indsynth or dmat or indole_PTase)"
                     /neighbourhood="10000"
                     /product="indole"
                     /protocluster_number="1"
     gene            complement(951..1730)
                     /locus_tag="KGS77_RS27180"
                     /old_locus_tag="KGS77_26980"
     CDS             complement(951..1730)
                     /EC_number="2.1.-.-"
                     /GO_function="GO:0008168 - methyltransferase activity
                     [Evidence IEA]"
                     /GO_function="GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1089: methyltransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017238871.1"
                     /locus_tag="KGS77_RS27180"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KGS77_26980"
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="WP_242587711.1"
                     /transl_table=11
                     /translation="MSAPAVPPTARHTVRQELLSRQLDEQIAARFPVGQRLEVLGVGLG
                     EGFQALRLARAGHKVTGLEPDPAMLDVARTVLSREPEGIQERVRLIQGDGGETGVHFLP
                     GTFDIVLCHGVLMDAPAPDPDPLLAGLARMLAPGGLLSLVVRNADAPAMRPGLDGDWER
                     ALTAFESADARYRLDALTTTLAGIGAPLHTWYGVQVFTGHSEAGDPASASGEGPVSAEG
                     PVSGEGLERLLAAEDRAARTDPYRAVAELLHLCGVRG"
     gene            complement(1727..2323)
                     /locus_tag="KGS77_RS27185"
                     /old_locus_tag="KGS77_26985"
     CDS             complement(1727..2323)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018539624.1"
                     /locus_tag="KGS77_RS27185"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KGS77_26985"
                     /product="DUF3043 domain-containing protein"
                     /protein_id="WP_242585803.1"
                     /transl_table=11
                     /translation="MFRSRTKDEQAAPAKVTADQSKQPRDPQAPKGRPTPKRSDAQSQR
                     RTRAHTPANRKDAARAAREARRADLTKQREALANGDERYLPVRDKGPVRRFARDFVDSR
                     WSVAEFFLPVAVLILVLTMIRVPQIQSIALLMWLALIVLIVLDSIGIWIRLGKRLNERF
                     PGENIKGAKAYAVMRTLQMRRLRLPKPQVKRGERP"
     gene            2618..3415
                     /locus_tag="KGS77_RS27190"
                     /old_locus_tag="KGS77_26990"
     CDS             2618..3415
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016639594.1"
                     /locus_tag="KGS77_RS27190"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KGS77_26990"
                     /product="PspA/IM30 family protein"
                     /protein_id="WP_242585804.1"
                     /transl_table=11
                     /translation="MSGVMKRMGMVFRAKANKALDRAEDPRETLDYSYQKQLELLQKVR
                     RGVADVATSRKRLELQLNQLQGQSSKLEDQGRKALALGREDLAREALSRRAALQQQVTD
                     LETQHQTLQGEEEKLTLAAQRLQAKVDAFRTKKETIKATYTAAQAQTRIGEAFSGISEE
                     MGDVGMAIQRAEDKTAQMQARAGAIDELLASGALDDPTGMAKDDIAAELDRLSGGTDVE
                     LELQRMKAELAGGTSAGQQAIEGGRPGQAQPVQPQDRPRFDKQ"
     gene            3484..3762
                     /locus_tag="KGS77_RS27195"
                     /old_locus_tag="KGS77_26995"
     CDS             3484..3762
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010037210.1"
                     /locus_tag="KGS77_RS27195"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KGS77_26995"
                     /product="hypothetical protein"
                     /protein_id="WP_242585805.1"
                     /transl_table=11
                     /translation="MIVRIMGEGQVKLADAHFIELNKLDDELLDEMESGDEAGFRRTLG
                     ALLDAVRRLGEPLPDDALEPSELILPGPDATLDEVRQMLSDDGLIPG"
     gene            4013..5377
                     /locus_tag="KGS77_RS27200"
                     /old_locus_tag="KGS77_27000"
     CDS             4013..5377
                     /GO_function="GO:0000155 - phosphorelay sensor kinase
                     activity [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1048: sensor
                     histidine kinase"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009718577.1"
                     /locus_tag="KGS77_RS27200"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KGS77_27000"
                     /product="sensor histidine kinase"
                     /protein_id="WP_242587712.1"
                     /transl_table=11
                     /translation="MRAHPLAADSVLAVVLFAVTLVIAVTDPHGPNGPRYGARELTAPT
                     VVLAAFACSSLLLRRRFPRSVLAFTTALAVLELFAEGPVPRAPVACAAVIALYTLASRT
                     DRSTTWRIGALTALVLTAAVMLFGTGPWYSQENVGVFAWTGLAAAAGDAVRSRRAYIAA
                     IRERAERAERTREEEAGRRVAEERMRIARELHDVVAHHIALVNVQAGVASHVMDSRPDQ
                     AKQALAHVREASRSALEELRATVGLLRQHGDPTAPTEPAPGLGVLDQLIDGFTRAGLPV
                     DLETPPRPDGLPASVDLAAYRIVQEALTNVHKHAGPGARATVRIVRTQDALTVTVLDDG
                     AGVPGHTGAPKDAGVSKDAGVPPRRRPDPYTNGAGTPTNKTDPEAKWTGTEANRTHPEA
                     NRTGTASDGGGHGLIGMRERVAALRGTVETGPRPSGGFRVRVRLPLHQSRTGETT"
     gene            5374..6075
                     /locus_tag="KGS77_RS27205"
                     /old_locus_tag="KGS77_27005"
     CDS             5374..6075
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1016: LuxR family
                     DNA-binding response regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018090107.1"
                     /locus_tag="KGS77_RS27205"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KGS77_27005"
                     /product="response regulator transcription factor"
                     /protein_id="WP_242585806.1"
                     /transl_table=11
                     /translation="MTIKVLLADDQALLRSAFRVLVESEPDMEVAGEASDGAEAYELAR
                     ARGADVVLMDIRMPGVDGLAATRMISQDPELADVRVVILTTFEVDDYVVQALRAGASGF
                     LGKGAEPDELLSAIRIAAAGEALLSPTATKGLIAQFLAQGEGGPGEGSGGPGADRLGAL
                     TGREREVLVLVGGGLSNDEIAERLAVSPLTVKTHVNRAMAKLGARDRAQLVVIAYETGL
                     VRPRVGGASPQ"
     misc_feature    complement(6147..6156)
                     /note="TFBS match to ToxT, Regulator of MSHA biosynthesis,
                     confidence: weak, score: 13.82"
                     /tool="antismash"
     gene            6240..9422
                     /locus_tag="KGS77_RS27210"
                     /old_locus_tag="KGS77_27010"
     CDS             6240..9422
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1049:
                     AcrB/AcrD/AcrF family protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003982388.1"
                     /locus_tag="KGS77_RS27210"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KGS77_27010"
                     /product="efflux RND transporter permease subunit"
                     /protein_id="WP_242585807.1"
                     /transl_table=11
                     /translation="MSWLSRLSLVQRGLIALMSIVAIAFGAIAIPQLKQQLLPSIELPM
                     VSVLAPYQGASPDVVEKQVVQPLEDGIRAVDGIKGVTSKAGEGSGVIMAQFDYGNDSKR
                     LVADVQQAVNRARARLPKDVDPQVVAGSTDDMPTVVLAVSSSDKDQQTLADQLKRSVVP
                     ALKNIDGVGQVTVDGVQDRVVAVTPDEKKLARAGLTAAALGQALEANGASVPAGSFAEG
                     GRSKTVQVGSGYTSVKQIQDLTVVPGAGPGGPGGAGGGQQARPVRVGDIATVKEEQATP
                     TSITRTDGAPSLAVMVTMAQDGSAVAISDAVKDKLPQIRADLGKGAKVTVASDQGPAVS
                     RSIESLTTEGLLGLVMAVIVILVFLLSLRSTLVTAVSIPLSVVITLIVLWTRDLSLNML
                     TLGALTIAIGRVVDDSIVVLENIKRHLGYGEERQQAILTAVREVAGAITSSTLTTVAVF
                     LPIGVVGGMVGALFGSFSLTVAVALLSSLIVSLTVVPVLSYWFLRAPKIPEGADPDHLR
                     REAEEKEARSALQRLYVPVLRFATRRRLVSLLIAVAVLVATFAMGPLLKTNFFDQGKQD
                     TLSIKQELKAGTSLGAADAQAKKVEKLLSGLDAVQDYQVTVGSSGFMAAFGGGTGANQA
                     SYQVKLKDAADSQKVTDQIRKGLDQLGKGIGETTVTSGGGFGSQDLSVVVKAGDAKVLK
                     KAAEQVRKTVAGLDHVTDVQSDLSQSVPRISVTANDKAAAAGYSQAALGQAVAQAVRGT
                     TSGKAVLDDTERDIVVKSAHPATTEAELKNLALPTPAGTVSLGDIATVRTVDGPVRMTR
                     IDGARSATITAKPTGDNTGAVSADLQKRLKALKLPSGATAEVGGVSQDQTDAFSSLGLA
                     MLAAIAIVFMLLVATFRSLIQPLILLVSIPFAATGAIGLLVATGTPMGVPALIGMLMLI
                     GIVVTNAIVLIDLINQYRSQGYGVVEAVIEGGRHRLRPILMTALATIMALLPMALSVTG
                     DGGFISQPLAVVVIGGLITSTLLTLLLVPTLYAMIELRKERRAKKKAAKRSAGGTAPKS
                     GDQARTPEPAGV"
     gene            10001..11107
                     /locus_tag="KGS77_RS27215"
                     /old_locus_tag="KGS77_27015"
     CDS             10001..11107
                     /GO_function="GO:0016765 - transferase activity,
                     transferring alkyl or aryl (other than methyl) groups
                     [Evidence IEA]"
                     /GO_process="GO:0009820 - alkaloid metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters) indole:
                     indole_PTase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF023417.4"
                     /locus_tag="KGS77_RS27215"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KGS77_27015"
                     /product="tryptophan dimethylallyltransferase family
                     protein"
                     /protein_id="WP_242585808.1"
                     /sec_met_domain="indole_PTase (E-value: 3.2e-102, bitscore:
                     340.8, seeds: 22, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSSLRSVPRISASTTFSDYALTTAARLLGSAGLDVEQGTRVLRTM
                     LSPWGARRIGTRPDWHSDVCADGSPIEFSAAFAREGLQLRVLVEALPDRLSTSDAQEAA
                     LGLTRGLIQDFGAADNRLASVSDLFLPKEDPAGFAMMHAATLARTGGPEFKVYLNPNAD
                     ESMTGTERTREALDRLGFEKAWTAVEEYARRGFDLDRIVYFGLDLIDGPESRVKVYFRH
                     YDISPAELDARMEISLQHEAGFLGEFCRRLTGSDSEVRAQPLVSNLTFTTAGGDTPVSA
                     TVYVPLWLHTASDRIVRDRVSSVMADMDLPVGSYQLLLSHMARRPLPAGRGIHTYASAR
                     VQHGRPRLTTYWSPELYDRYPPARYQRG"
     gene            11113..12351
                     /locus_tag="KGS77_RS27220"
                     /old_locus_tag="KGS77_27020"
     CDS             11113..12351
                     /NRPS_PKS="Domain: Aminotran_1_2 (35-390). E-value:
                     2.3e-42. Score: 137.3. Matches aSDomain:
                     nrpspksdomains_KGS77_RS27220_Aminotran_1_2.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Aminotran_1_2"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) DegT_DnrJ_EryC1"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1019: aminotransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003985360.1"
                     /locus_tag="KGS77_RS27220"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KGS77_27020"
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="WP_242585809.1"
                     /sec_met_domain="Aminotran_1_2 (E-value: 2.7e-40, bitscore:
                     137.3, seeds: 48, tool: rule-based-clusters)"
                     /sec_met_domain="DegT_DnrJ_EryC1 (E-value: 5e-06, bitscore:
                     24.6, seeds: 38, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLPHEAYRPLFDDAQVRPGLLRQRSPLRWGACPPGVIPLTAAEPD
                     FPGPPVVRDALISAVADGYFPYASPLGCDELRETFCEVARARYGITGHPGSVVPTPGTA
                     AALWGVVHLLCGQGDECILLDPVDLLFGQAVDAAGARRVYCPVDKSTGLLDADRLASLI
                     TSRTALICLCNPHNPLGTVFDERTLRAVAETAGRHRIPILCDEVWNEIVHPPGRHISMA
                     SLETGNSRRIYTVTGLSKTFALPGLRTGFVLAPTPREADALQLTFQRLGAAYSMTPFSQ
                     AGALAALRHGWPWKDAFLEHLRGVRDYCVDRLNAIPGITCGRPEGTYVLFPDVSATGLS
                     SRAMGGFLLSRARVAVVPGTPEWFGPAAEGNIRISYATSRAVVREALDRIAEAVEELVT
                     GGPAVLQAAGTGR"
     aSDomain        11218..12282
                     /aSDomain="Aminotran_1_2"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_KGS77_RS27220_Aminotran_1_2.1"
                     /evalue="2.30E-42"
                     /label="KGS77_RS27220_Aminotran_1_2.1"
                     /locus_tag="KGS77_RS27220"
                     /protein_end="390"
                     /protein_start="35"
                     /score="137.3"
                     /tool="antismash"
                     /translation="VIPLTAAEPDFPGPPVVRDALISAVADGYFPYASPLGCDELRETF
                     CEVARARYGITGHPGSVVPTPGTAAALWGVVHLLCGQGDECILLDPVDLLFGQAVDAAG
                     ARRVYCPVDKSTGLLDADRLASLITSRTALICLCNPHNPLGTVFDERTLRAVAETAGRH
                     RIPILCDEVWNEIVHPPGRHISMASLETGNSRRIYTVTGLSKTFALPGLRTGFVLAPTP
                     READALQLTFQRLGAAYSMTPFSQAGALAALRHGWPWKDAFLEHLRGVRDYCVDRLNAI
                     PGITCGRPEGTYVLFPDVSATGLSSRAMGGFLLSRARVAVVPGTPEWFGPAAEGNIRIS
                     YATSRAVVREALDRI"
     gene            complement(12383..13921)
                     /locus_tag="KGS77_RS27225"
                     /old_locus_tag="KGS77_27025"
     CDS             complement(12383..13921)
                     /GO_function="GO:0004497 - monooxygenase activity [Evidence
                     IEA]"
                     /GO_function="GO:0005506 - iron ion binding [Evidence IEA]"
                     /GO_function="GO:0016705 - oxidoreductase activity, acting
                     on paired donors, with incorporation or reduction of
                     molecular oxygen [Evidence IEA]"
                     /GO_function="GO:0020037 - heme binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1007: cytochrome P450"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003985359.1"
                     /locus_tag="KGS77_RS27225"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KGS77_27025"
                     /product="cytochrome P450"
                     /protein_id="WP_242585810.1"
                     /transl_table=11
                     /translation="MTSSFPEQPRTTWASAPPPQCPAHDRFGAADGLARLFGPEAAEDP
                     MGLYERLRARHGSVAPVLLDGDLPAWLVLGYREILEVAGTPARFSRDSRNWRWFKEGRV
                     PPDSPLLPMIAWQPVCLFLDGEERARLRLAVTESLERFNRRGIRRHITRFTHQLVDGFA
                     GRGEADLAEEFCEHLPMLVLTQLLGMPDEYGPRLVAASRDMVAGTETSVASNAFIVETL
                     TDLVRRKRGSRGHDITSWLIDHSSGLTDEEVWNHLRVILIAANETTVNLLKSTLRMVLT
                     DPRCHASLAGGQMTLPDVVEQVLWSEPPLMTVPGRWAAVDTEVGGQKVEAGDMLLLCLA
                     AGNYDPAVRPDPSVPLHGNRSHLAFSSGPQECPGQNIGRAIADTGIDALLSRLPDVRLS
                     IPEEELRWTSGWMTRHLASLPVTFTASRTTDSAASAGPAAAPATAAASLTSATAGHPAR
                     GATGNGSGPAAGPRVPFPSVPFPSVPFPPVAPPPVPAHRRRTSWWRSFKAWLHG"
     gene            complement(13918..14556)
                     /locus_tag="KGS77_RS27230"
                     /old_locus_tag="KGS77_27030"
     CDS             complement(13918..14556)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014056720.1"
                     /locus_tag="KGS77_RS27230"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KGS77_27030"
                     /product="ATP/GTP-binding protein"
                     /protein_id="WP_242585811.1"
                     /transl_table=11
                     /translation="MDYKISDYRLSEPVVGPRCEDALPASVTTAVKVVIVGGFGVGKTT
                     LVGSVSEIKPLTTEEIMTQAGAEVDDIAGVERKNETTVAMDFGRITLSDKLVLYVFGTP
                     GQQRFWFLWNGLFEGALGAVVLIDTRRLEDSFDVMGRLEERGVPFIVAINAFPDAPCYP
                     ASELREALDIPDGVPVIDCDARERASSREGLLTLVRYLHALTTTTPERR"
     gene            complement(14537..14911)
                     /locus_tag="KGS77_RS27235"
                     /old_locus_tag="KGS77_27035"
     CDS             complement(14537..14911)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003985357.1"
                     /locus_tag="KGS77_RS27235"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KGS77_27035"
                     /product="DUF742 domain-containing protein"
                     /protein_id="WP_242585812.1"
                     /transl_table=11
                     /translation="MSGPEQEEQQRAWEEGGPERLYVITSGRNLPDRQSRLDMVTLIVS
                     RGEAGPGMQPELAAVVRICDYPLSVAEISAYLHLPVSVIILLLTDLLASGHVEARASVL
                     TQSLPDVELLEAVMHGLQNL"
     gene            complement(14908..15294)
                     /locus_tag="KGS77_RS27240"
                     /old_locus_tag="KGS77_27040"
     CDS             complement(14908..15294)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018540698.1"
                     /locus_tag="KGS77_RS27240"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KGS77_27040"
                     /product="roadblock/LC7 domain-containing protein"
                     /protein_id="WP_242587713.1"
                     /transl_table=11
                     /translation="MDWMLEELASSVPQTRNVVVLSSDGLCMAQFGADNDTADRLAAAC
                     AGLQSLSAAIGAEFPRGDGRMKLVVVEVDGGFFYLMAAGAGAYLAVLADDDVDAGLMGQ
                     RMRDLVARIGQHLTTPPRADRQVP"
     gene            complement(15349..16791)
                     /locus_tag="KGS77_RS27245"
                     /old_locus_tag="KGS77_27045"
     CDS             complement(15349..16791)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018846605.1"
                     /locus_tag="KGS77_RS27245"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KGS77_27045"
                     /product="ATP-binding protein"
                     /protein_id="WP_242585813.1"
                     /transl_table=11
                     /translation="MWLLPPALLAICAAVAVPLLPTAARSHAVWIGVVATAAVAFAGGK
                     AARRGRAIDELRRQYAEREAALQRQMAQQEAETLRMAKETLPAAMARLQKGMPVEDVLR
                     STCQVSRVSPGFEAAHHAVLRYVLQAVEAEEDLRDAAQRAFVNIARRVQAIVHQQALEL
                     REMEDRHGQDPQVFGDLLHLDHRTALIGRLADSIAVLGGARPGRQWQKDIPLFNVLRGA
                     MSRITDYQRVDLHSVADVGVLGRAAEPLIHAVAELLDNATRYSPPQTRVHLTATEVQSG
                     VAVEIEDAGLGLTDEARIRAERALAQHSSSGLDLDDLGESPRLGLAVVGRLSHTNRFKV
                     ALRVSAYGGVRVVLVVPPDLITVTPVPGGALAKAPSLPPPRRPSGPKHRAEAAMEEPVP
                     TTGSRTANGLPQRRRRTRAVIPSVRPQQAASAADSRPPASAGQPPPAGLWMSAFLDGAS
                     GASADGSPAHRPHGPSDEEPEQ"
     misc_feature    complement(16981..16994)
                     /note="TFBS match to ArgR, Regulator of arginine
                     biosynthesis genes, confidence: strong, score: 19.68"
                     /tool="antismash"
     misc_feature    complement(17131..17143)
                     /note="TFBS match to LuxO, Repressor of luminescence,
                     confidence: weak, score: 17.22"
                     /tool="antismash"
     gene            complement(17185..17385)
                     /locus_tag="KGS77_RS27250"
                     /old_locus_tag="KGS77_27050"
     CDS             complement(17185..17385)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010358154.1"
                     /locus_tag="KGS77_RS27250"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KGS77_27050"
                     /product="DUF397 domain-containing protein"
                     /protein_id="WP_242585814.1"
                     /transl_table=11
                     /translation="MHHSPDVSTAHWRASSYSNANGGNCVEITEDLPGLVPVRDSKNPH
                     GPILTFPTASWTAFITALKTA"
     gene            complement(17364..18209)
                     /locus_tag="KGS77_RS27255"
                     /old_locus_tag="KGS77_27055"
     CDS             complement(17364..18209)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003989699.1"
                     /locus_tag="KGS77_RS27255"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KGS77_27055"
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="WP_242585815.1"
                     /transl_table=11
                     /translation="MKFTSRTLTPYVSARHYFGSEQRRHREAAKLSLVQLAAIVNSSKS
                     TLARIETAELMPPSDLPVRLDAAFGTGKHFYDLYQLAKREVHPDQYRRFMDLEAQAETI
                     ENYEPQVVPGCLQTEAYARVLFRSLGCWTDEQIEERVAARLSRRERQYSATPPYRWAII
                     DESVLRRPAGSEECMYEQLASLLEQVDTPYSKVQVVPFNAGLHTLMSGALTLLTLPNGS
                     SVAYEEGIEAGHLYEVPEAVKKWRRQYEVLRAIALSPAESAKLIRKAMEDYQSCITPPM
                     "
     misc_feature    18269..18279
                     /note="TFBS match to HypR, L-hydroxyproline utilization
                     repressor, confidence: weak, score: 18.79"
                     /tool="antismash"
     gene            18348..18596
                     /locus_tag="KGS77_RS27260"
                     /old_locus_tag="KGS77_27060"
     CDS             18348..18596
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="KGS77_RS27260"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="KGS77_27060"
                     /product="hypothetical protein"
                     /protein_id="WP_242587850.1"
                     /transl_table=11
                     /translation="MFHRIARFAVALSRGLLPGTGRHRACGAPPARAGRYVPAVRTPRR
                     RPEVMLRGEASALVRPYTLSPEEFRTWRTRRAGAGAR"
     misc_feature    complement(18648..18663)
                     /note="TFBS match to DasR, N-acetylglucosamine dependent
                     repressor, confidence: weak, score: 20.49"
                     /tool="antismash"
     gene            18707..18988
                     /locus_tag="KGS77_RS27265"
                     /old_locus_tag="KGS77_27065"
     CDS             18707..18988
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="KGS77_RS27265"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="KGS77_27065"
                     /product="hypothetical protein"
                     /protein_id="WP_347404535.1"
                     /transl_table=11
                     /translation="MSLLADEAEEELLAAAESLLSDAGPLPVVADLAAPELRRVIARFD
                     RALRDVLCIAVSRGARLIQGEAPPCEHGTTEQCDGKTFCCGCRRQIYL"
     gene            complement(19095..19628)
                     /locus_tag="KGS77_RS27270"
                     /old_locus_tag="KGS77_27070"
     CDS             complement(19095..19628)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="KGS77_RS27270"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="KGS77_27070"
                     /product="hypothetical protein"
                     /protein_id="WP_242585816.1"
                     /transl_table=11
                     /translation="MSDFRPKTGPKAGRRQPAEKRNGRFKRGLGGSLAVIVFAAAVSAC
                     GSDDKSAKGDKGDKDKPAASAPASTSAEASHKAAPTPTHKAKPTTVLALKGFRTKNTSA
                     FMVGGEWTLSYTFDCTKAMAAVDGKGNFIVFEKNDKLVNELGKTGKGSIQQHTPGTHQL
                     QIISECDWTVKVTG"
     gene            complement(19868..21046)
                     /gene="nadA"
                     /locus_tag="KGS77_RS27275"
                     /old_locus_tag="KGS77_27075"
     CDS             complement(19868..21046)
                     /EC_number="2.5.1.72"
                     /GO_function="GO:0008987 - quinolinate synthetase A
                     activity [Evidence IEA]"
                     /GO_function="GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA]"
                     /GO_process="GO:0009435 - NAD biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="nadA"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020130009.1"
                     /locus_tag="KGS77_RS27275"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KGS77_27075"
                     /product="quinolinate synthase NadA"
                     /protein_id="WP_242585817.1"
                     /transl_table=11
                     /translation="MTTAQPLDVQPTPLALLLLGREADPKSERGVECPGDLPAPSDPDL
                     VERARAAKEKLGDKVFILGHHYQRDEVIEFADVTGDSFKLARDAAARPDAEYIVFCGVH
                     FMAESADILTTDEQQVVLPDLAAGCSMADMATAEQVAECWDVLTEAGVAEQVVPVSYMN
                     SSADIKAFTGKHGGTICTSSNAKRALDWAFEQGEKVLFLPDQHLGRNTAVRDMGMSLED
                     CVVYNPHKPNGGLTAEQLRAAKMILWRGHCSVHGRFSLESVEDVRARIPGVNVLVHPEC
                     KHEVVAAADYVGSTEYIIKTLEAAPAGSKWAIGTELNLVRRLANRFASEGKEIVFLDKT
                     VCFCSTMNRIDLPHLVWTLESLASGKVVNRIQVDPETESFAKLALERMLALP"
     misc_feature    complement(21087..21107)
                     /note="TFBS match to NrtR, NAD synthesis repressor,
                     confidence: weak, score: 24.35"
                     /tool="antismash"
ORIGIN
        1 gacgccttga ccgtacggaa ggcgccgaag gtgcgctcca gcgcggcgga gaccgcgccg
       61 accgactcct gcgcgtgctt ggtcgcccgc gcgatctgcg gcatgaccag ccccagcgaa
      121 ccggcgatga gcacgatcac ggcgagcgtg acaccgagca gcacggggtc cagcagcgcc
      181 atcatcacga ccgtgacgat cagtgagagg ccgctggtca ccgtggagac cagcgcctgg
      241 gtggtcaccg agcgcagcag tgtggtgtcg gaggtgaccc gggacatcag gtcgccgggc
      301 tgggtccgtt cgaccgccgg catccgcagc cgcagcagcc gtgcgacgag ctggcggcgg
      361 gcggccagga ccacggactc ggcggtgcgc tccaggacgt acgcgcccag cgactcgatc
      421 gccgtacccg ccaggaccag cgcggtgagc aggagcagca gggaggcgat cgattcctcg
      481 ccgccgagcc gttcgaccag tgccttggcc gcgagcggct gggcgaggcc ggtgaccacg
      541 ccgatcaggg tgaggaagcc gcccagggcg acggcggcgc ggtgcggacg gatgtggccg
      601 tacagaatgc gccaggtacg ggcggccggc agccggggcg cgggcggctc gccggacgca
      661 ccggagccct tccgcccgtc gggcccgtcc gctccgtccg cctttccgag ctgtacggat
      721 tcctcggacc cgtccgtcct tccgggccgc acgggcttct ccggcccgtc ggtcccgctc
      781 cgcccgacgc ggtccgccgg cccctgcccc gcgtttcctc gacattgctg gtcacaccgg
      841 aaaggacgcg gcaggggtcc ggttcacctg cctgccggcg gaaaccggcc gatcatttga
      901 ccgataacgg tcggtcgacg gccctgtgtg tcatcggcac ccggtacgcg tcagccgcgt
      961 acgccgcaca ggtgcagcag ttcggccacc gcgcggtacg ggtcggtgcg cgcagcccgg
     1021 tcctcggcgg ccagcagccg ctccagccct tcgccggaca ccggcccttc ggcggacacc
     1081 ggcccttcgc cggacgccga cgccgggtcc ccggcttccg agtggcccgt gaagacctgt
     1141 acgccgtacc aggtgtgcag cggcgccccg atgccggcga gcgtcgtggt cagcgcgtcg
     1201 agccggtagc gcgcgtcggc gctctcgaag gcggtcaggg cacgttccca gtcgccgtcc
     1261 agccccggcc gcatggccgg cgcgtccgcg ttccgtacga ccagggacag cagcccgccg
     1321 ggggccagca tccgcgccag tccggccagc agcgggtccg ggtcgggcgc cggggcgtcc
     1381 atcagcacgc cgtggcacag cacgatgtcg aaggtgccgg gcaggaagtg gacaccggtc
     1441 tcgccgccgt ccccctggat cagccgtacc cgctcctgga tgccttccgg ctcccgcgac
     1501 agcaccgtac gcgccacgtc cagcatcgcc gggtcgggct ccaggccggt gaccttgtgg
     1561 cccgcgcggg ccagccgcag cgcctggaag ccctcgccca gcccgacgcc caggacctcc
     1621 agccgctgcc ccacggggaa gcgcgcggct atctgctcgt cgagctgacg ggagagcagt
     1681 tcctgccgga cggtgtgccg tgccgtgggc ggtacggccg gtgcgctcag ggccgttccc
     1741 cgcgcttgac ctgcggcttg ggcagccgca gccggcgcat ctggagcgtg cgcatcacgg
     1801 cgtacgcctt ggcgcccttg atgttctcgc cggggaagcg ctcgttgagg cgcttgccca
     1861 gacggatcca gatgccgatc gagtccagca cgatcagcac gatcagggcc agccacatca
     1921 gcagcgcgat gctctggatc tgcggtacgc ggatcatcgt gagcaccagg atgagcacgg
     1981 ccaccggcag gaagaactcc gccacgctcc agcgggagtc gacgaagtcc cgcgcgaagc
     2041 ggcgcaccgg gcccttgtcg cgtacgggca ggtaacgctc gtcgccgttg gccagcgcct
     2101 cccgctgctt ggtcaggtcg gcccggcggg cctcgcgggc cgcccgcgcc gcgtccttgc
     2161 ggttggcggg ggtgtgcgcg cgggtccggc gctgcgactg ggcgtcgctg cgcttgggcg
     2221 tcgggcggcc cttgggggcc tgcgggtcgc ggggctgctt ggactggtcc gcggtcacct
     2281 tggcgggcgc ggcctgctca tccttcgtac ggcttcggaa cacagaaccc aagggtacgg
     2341 ggtggcggcg catggatgac gggcgcatgg ggaacgatcc ggcaacggcg tccgtccccg
     2401 cccggtgccg taccgggacg aagcggacgc ggtggccttt gtacggccgt cccctaatcc
     2461 ctgggcggga gagcggggag tccctgatcg tcctgtagga ggagcgcatc acggcccgat
     2521 cggtgcggta atggaaccag ggcccgtact gtggggtctg taggtgtgct ggagtcgaag
     2581 cccgaagtac tcggtcagaa gggggcgcgc gaggcccatg agcggtgtca tgaagcggat
     2641 ggggatggtc ttccgcgcga aggccaacaa ggccctggac cgtgccgagg atccgcgtga
     2701 gaccctcgac tactcgtacc agaagcagct cgaactgctc cagaaggtac gccgcggcgt
     2761 cgccgacgtg gcgacctccc gcaagcgcct ggagcttcag ctcaaccagc tccagggcca
     2821 gtcctccaag ctggaggacc aggggcgcaa ggcgctggcg ctgggccggg aggacctcgc
     2881 ccgcgaggcg ctctcccgcc gtgccgcgct gcagcagcag gtcacggacc tggagacgca
     2941 gcaccagacg ctccagggcg aggaggagaa gctcaccttg gcagcgcagc ggctgcaggc
     3001 caaggtcgac gccttccgta cgaagaagga gaccatcaag gccacgtaca cggctgccca
     3061 ggcgcagacc cgcatcggcg aggcgttctc cggcatctcc gaggagatgg gcgacgtcgg
     3121 catggccatc cagcgcgcgg aggacaagac cgcgcagatg caggcgcggg ccggcgcgat
     3181 cgacgaactg ctcgcctcgg gcgcgctgga cgacccgacc ggcatggcca aggacgacat
     3241 cgcggccgag ctggaccggc tctccggcgg caccgacgtg gaactggagc tccagcggat
     3301 gaaggcggag ctggcgggag gcacctcggc cggccagcag gccatcgagg gcggccggcc
     3361 cggtcaggcg cagcccgtcc agccgcagga ccggccgcgt ttcgacaagc agtgaccgtc
     3421 ggccgcggtt agcctcgtca ggatcgtctc aagatcgtcc caccggagca gagggagacc
     3481 gtcgtgatcg tacggatcat gggggagggg caggtgaagc tggccgacgc ccacttcatc
     3541 gagctgaaca agctggacga cgaactgctc gacgaaatgg agagcggtga cgaggccggc
     3601 ttccggcgca ccctcggcgc cctgctggac gcggtgcgcc ggctgggcga accgctgccg
     3661 gacgacgccc tggagccgtc ggagctgatc ctcccgggtc cggacgccac cctcgacgag
     3721 gtccggcaga tgctcagcga cgacggcctg atccccggct gagacgctgc acccgcgacc
     3781 gagacgcttc gcccgcggct gagacgctgc ccccgcggct gagacgtctc ggcccggccg
     3841 aaccgctcac ctccggccgg gcgacgaccg cagatcctcc agcgcagacg gcgccccgga
     3901 cccagacggg tccggggcgc cgccgttccc tcgcgcgcta ccgtttcctc ccgtgactcc
     3961 cctcgccccc ggccgggcca ccccgcgccc gggcccggtc cgcttcccgc gcctgcgggc
     4021 gcaccccctg gccgccgact ccgtcctggc ggtcgtcctg ttcgccgtga ccctggtcat
     4081 cgccgtcacc gacccgcacg gccccaacgg cccccggtac ggcgcccgcg agctgaccgc
     4141 gccgaccgtg gtgctggccg ccttcgcctg ctcgtcgctg ctgctgcgcc gccgcttccc
     4201 gcgcagcgtc ctggccttca ccaccgccct ggcggtcctg gagctgttcg ccgaggggcc
     4261 cgtgccgcgc gctccggtcg cctgtgccgc cgtcatcgcc ctgtacaccc tggcctcccg
     4321 caccgaccgg tccacgacct ggcgcatcgg agcgctgacg gccctggtgc tcaccgccgc
     4381 cgtgatgctg ttcgggaccg ggccctggta ctcccaggag aacgtggggg tcttcgcctg
     4441 gaccggcctg gccgcggcgg ccggtgacgc ggtccgcagc cgccgcgcct acatcgccgc
     4501 catacgggaa cgggccgagc gcgcggagcg cacccgcgag gaggaggccg gccgtcgcgt
     4561 cgccgaggag cggatgcgca tcgcccgcga gctgcacgat gtcgtcgccc accacatcgc
     4621 gctggtcaac gtgcaggccg gggtcgcctc gcacgtcatg gacagccgcc ccgaccaggc
     4681 caagcaggcg ctcgcccacg tccgcgaggc cagccgctcc gcactggagg aactgcgcgc
     4741 caccgtcggc ctgctgcgcc agcacggcga ccccacggcc cccaccgagc ccgcgccggg
     4801 cctgggcgtc ctggaccagc tcatcgacgg cttcacccgc gccggacttc ccgtggacct
     4861 ggagaccccg ccgcgccccg acggcctgcc ggcctccgtc gacctggccg cgtaccggat
     4921 cgtccaggag gccctgacca acgtgcacaa gcacgcgggc ccgggagcgc gcgccacggt
     4981 acgtatcgtc cggacgcagg acgcgctgac cgtgacggtg ctggatgatg gcgcgggcgt
     5041 acccgggcac acgggcgcac ccaaggacgc gggcgtatcc aaggacgcgg gggtgccacc
     5101 gcgccgccgt ccggacccgt acacgaacgg agccggcacg cccacgaaca aaactgatcc
     5161 agaagcgaaa tggaccggta cggaagcgaa ccggacccac ccggaagcga accggaccgg
     5221 cacggcgtcc gacggcggcg gccacggcct gatcggcatg cgcgagcggg tcgccgccct
     5281 gcgcggcacc gtggagaccg gcccccgccc gagcggcggc ttccgggtac gcgtacgcct
     5341 tccgcttcac cagtcccgta cgggggagac gacatgacca tcaaggtgct gctcgccgac
     5401 gaccaggcgc tgttgcgcag cgcgtttcgc gtgctggtgg agtccgagcc ggacatggag
     5461 gtggcggggg aggcgtccga cggcgccgag gcgtacgaac tcgcccgggc ccggggtgcc
     5521 gacgtggtcc tgatggacat ccggatgccc ggtgtggacg ggctggccgc cacccgcatg
     5581 atcagccagg acccggagct ggcggacgta cgcgtggtga tcctgacgac cttcgaggtg
     5641 gacgactatg tcgtccaggc gctgcgggcc ggcgccagcg gcttcctggg caagggggcc
     5701 gagccggacg agctgctgag cgccatccgt atcgcggcgg ccggtgaggc gctgctgtcc
     5761 ccgacggcca ccaaggggct gatcgcccag ttcctggcgc agggcgaggg cgggcccggc
     5821 gaggggagcg gcgggcccgg cgcggaccgg ctgggcgcgc tgaccggccg ggagcgcgag
     5881 gtgctggtgc tggtcggcgg cgggctctcc aacgatgaga tcgccgaacg gctggcggtc
     5941 agtccgctca ccgtcaagac ccatgtcaac cgcgcgatgg cgaaactggg tgcccgggac
     6001 cgcgcccagt tggtggtcat agcgtacgaa accggacttg tgcgcccgag ggtcggcggc
     6061 gcttccccgc agtagttggg ggagggtgga gacggacgta ctccgaacgc ggtagagagg
     6121 gcgcccccga aaccgacctg ggagcgacaa aaaacgggtg ggacagcacc gatggtgtag
     6181 gtgggcgcga atgccccctt ctgccgagta cctctgtcac aagaagagag accccaccca
     6241 tgtcctggct gtcccgactc agcctcgtac aacggggcct gatagcgctg atgtcgatcg
     6301 tggcgatcgc cttcggcgcc atcgcgatac cccagctcaa acagcagctc ctgccctcca
     6361 tcgaactccc catggtctcg gtgctggcgc cgtaccaggg agcgtcgccc gacgtcgtgg
     6421 agaagcaggt cgtccagccg ctggaggacg gcatccgggc ggtcgacggc atcaagggcg
     6481 tcacgtccaa ggccggcgag ggctcgggcg tgatcatggc ccagttcgat tacggcaacg
     6541 actccaagcg gctggtcgcc gacgtccagc aggccgtcaa ccgcgcccgc gcccggctgc
     6601 ccaaggacgt cgacccgcag gtcgtcgccg ggtcgacgga cgacatgccc accgtcgtgc
     6661 tggcggtgtc ctcctcggac aaggaccagc agaccctcgc cgaccagctc aagcgcagcg
     6721 tcgtgccggc cctgaagaac atcgacggcg tcggccaggt cacggtggac ggcgtccagg
     6781 accgcgtcgt cgcggtcacc cccgacgaga agaagctcgc ccgggccggg ctgacggccg
     6841 cggcgctcgg ccaggcgctg gaggccaacg gggcatcggt gcccgccggt tccttcgccg
     6901 agggcgggcg cagcaagacc gtccaggtcg gctccggtta cacctccgtc aagcagatcc
     6961 aggacctgac ggtcgtgccg ggcgccggcc ccggaggacc ggggggagcc ggcggcggtc
     7021 agcaggccag gcccgtacgt gtcggtgaca tcgccaccgt caaggaggag caggccaccc
     7081 ccacctccat cacccgcacc gacggcgcgc ccagcctcgc cgtcatggtg accatggccc
     7141 aggacggcag cgcggtggcc atctccgacg cggtcaagga caagctgccc cagatccgtg
     7201 ccgacctcgg caagggcgcc aaggtcacgg tcgcctccga ccagggcccg gcggtctccc
     7261 ggtccatcga gtcgctgacc accgagggtc tgctcggcct ggtcatggcc gtgatcgtga
     7321 tcctggtctt cctgctgagc ctgcgctcca cgctggtgac cgccgtctcc atcccgctct
     7381 cggtcgtcat caccctgatc gtgctgtgga cccgtgacct gtcgctgaac atgctcacgc
     7441 tgggcgccct gacgatcgcc atcggccggg tcgtcgacga ctcgatcgtc gtcctggaga
     7501 acatcaagcg gcacctgggc tacggcgagg aacggcagca ggccatcctg accgccgtcc
     7561 gcgaggtcgc cggcgccatc acctcctcca cgctcaccac ggtcgcggtc ttcctgccga
     7621 tcggtgtcgt gggcggcatg gtcggcgccc tgttcggctc gttctccctg acggtggccg
     7681 tcgccctgct ctcctccctg atcgtctccc tgacggtcgt gccggtcctg tcgtactggt
     7741 tcctgcgcgc ccccaagatc cccgagggcg ccgacccgga ccacctgcgc cgcgaggccg
     7801 aggagaagga ggcccgcagc gcgctccagc gtctgtacgt ccccgtactg cgcttcgcca
     7861 cccgccgccg cctggtcagc ctgctgatcg cggtcgcggt gctggtcgcc acctttgcca
     7921 tgggcccgct gctgaagacc aacttcttcg accagggcaa gcaggacacc ctgagcatca
     7981 agcaggagct gaaggccggt acgagcctgg gcgccgccga cgcgcaggcc aagaaggtcg
     8041 agaagctgct gtccggcctg gacgcggtcc aggactacca ggtcaccgtc ggctcctccg
     8101 gcttcatggc ggccttcggc ggcggtacgg gcgccaacca ggcgtcgtac caggtcaagc
     8161 tgaaggacgc ggcggactcc cagaaggtca ccgaccagat ccgcaagggc ctggaccagc
     8221 tcggcaaggg catcggcgag accaccgtca ccagcggcgg cggcttcggc agccaggacc
     8281 tgagcgtggt ggtcaaggcc ggcgacgcga aggtgctgaa gaaggcggcg gagcaggtac
     8341 gcaagacggt ggccgggctc gaccacgtca ccgacgtaca gagcgacctg tcccagagcg
     8401 tgccccggat ctcggtgacg gccaacgaca aggcggcggc ggccggttac agccaggctg
     8461 ccctcggcca ggccgtcgcc caggcggtgc gcggcaccac cagcggcaag gcggtcctgg
     8521 acgacaccga gcgcgacatc gtggtgaagt ccgcccaccc ggccaccacc gaggccgagc
     8581 tgaagaacct ggccctgccc actcccgccg gcaccgtcag tctcggtgac atcgccaccg
     8641 tccgcacggt cgacgggccg gtccggatga cccggatcga cggcgcgcgg tccgcgacga
     8701 tcactgccaa gccgaccggc gacaacaccg gcgcggtcag cgcggacctc cagaagcggc
     8761 tcaaggcgct caagctcccc tcgggagcca ccgccgaggt cggcggcgtc tcgcaggacc
     8821 agaccgacgc gttctcctcg ctgggcctgg ccatgctcgc cgccatcgcg atcgtcttca
     8881 tgctgctggt ggcgaccttc cggtcgctga tccagccgct gatcctgctg gtctcgatcc
     8941 ccttcgcggc caccggcgcg atcggtctgc tggtcgccac cggcaccccc atgggtgtcc
     9001 cggcgctgat cggcatgctg atgctcatcg gcatcgtcgt caccaacgcc atcgtcctga
     9061 tcgacctgat caaccagtac cggtcgcagg gttacggtgt ggtcgaagcc gtcatcgagg
     9121 gcggccggca ccggctgcgc ccgatcctga tgacggcgct ggccacgatc atggccctgc
     9181 ttccgatggc cctgtccgtc acgggcgacg gcggcttcat ctcgcagccg ctggcggtgg
     9241 tcgtcatcgg cggtctgatc acctcgaccc tgctgacgct gctgctggtg ccgacgctct
     9301 acgcgatgat cgaactccgc aaggagcggc gggcaaagaa gaaggccgcc aagcggtcgg
     9361 cgggcggcac ggcgccgaag tccggggacc aggcccgtac cccggagccg gcgggcgtgt
     9421 gacgccggcc gtggcccgca tccggtagcg ccggggtcct tcggtccacg ggtgctgccc
     9481 ggagtgggaa cgacatgagc gagaccgccg cctcttggga ggcggcggtc tcgtcgtatc
     9541 cgggggcgag ggcacgggaa ctgttgagcc ggctgacgcg gcgtccgatt gaagtggctg
     9601 ccgatttaag cgcgtacggc cgaagtggcg ctcgtcggcg ttgtgggggc ggattcctgc
     9661 gcgccggagt gcgcatccgt ccgtcgggag cgcgcgccct tcatacgacg aacgccgcgc
     9721 acgccccttg tgcgccggtg gcggcgggcg gaagcatagt taattgtgaa agtaccccgg
     9781 gtccagggaa acggccgcgg tcgacggagg taatggacgg tatccgggtg gtaggccctg
     9841 ggcgaatacc gatgccgggg tgcggggacg gccggtcagg ccgtcggtcc cctatcggac
     9901 gggtagtcag gagccttgaa ccctattggt actggccgat cggccggcgg agcaagggcg
     9961 cggtacggcg atacccggca aaaggtaggg gaggaattcc atgtcgtctt tgcggtcggt
    10021 tccacggata tctgcgagca cgacgttctc ggactacgcg ctcaccaccg ccgcacgtct
    10081 cctcggcagt gcgggactgg atgtcgaaca gggcacgcgg gtactgcgca cgatgctgtc
    10141 accttgggga gcgaggcgga tcgggacacg tcccgactgg cactccgacg tatgcgccga
    10201 cggttcgccg atcgagttct ccgccgcctt cgcgcgggag ggactccagc tacgggtgct
    10261 cgtggaggcc ctgccggacc ggctgagcac atcggacgca caggaagcgg cactcggcct
    10321 cacccgtggg ctgatccagg atttcggcgc cgccgacaac cggctggcga gcgtctcgga
    10381 cctgttcctg ccgaaggagg acccggccgg cttcgccatg atgcacgccg ccaccctcgc
    10441 acggaccggc ggccccgagt tcaaggtcta cctcaatccg aacgccgacg agagcatgac
    10501 cggtaccgag cggacgcgtg aggcgctgga ccgcctgggg ttcgaaaagg catggaccgc
    10561 ggtcgaggaa tacgcccgcc ggggattcga cctcgacagg atcgtctact tcggtctcga
    10621 tctgatcgac ggccccgagt cgcgcgtaaa ggtgtacttc cgccattacg acatctcccc
    10681 ggcggaactc gacgcccgaa tggagatctc gctccagcac gaggccggat tcctggggga
    10741 attctgccgt cggctgaccg gcagcgacag cgaggtacga gcccagccgc tcgtcagcaa
    10801 cctgacgttc accacggccg gcggggacac gccggtgtcc gcgacggtgt acgtcccgct
    10861 gtggctgcac acggccagcg accggatcgt ccgggaccgc gtcagctcgg tcatggctga
    10921 catggacctg cccgtcggca gctatcagtt gctgctcagc cacatggccc ggcgtccgct
    10981 cccggccggc cgcggcatcc atacgtacgc ctcggcacgc gtgcagcacg gccgcccccg
    11041 tctgaccaca tactggtccc ccgagctcta cgaccggtac ccgcccgccc gctaccaacg
    11101 ggggtgaacc gcatgctgcc gcacgaagcc taccggccgc tgttcgatga cgcgcaggtc
    11161 cggcccggcc tgctgcggca gcgatcgcct cttcgctggg gcgcctgtcc gcccggcgtc
    11221 atcccgctga cggcggccga gcctgacttc cccgggcccc cggtggtcag ggacgccctg
    11281 atctcggccg tcgccgacgg ctatttcccc tatgcgtcac ccctgggatg cgatgagctg
    11341 cgggagacct tctgcgaggt ggcccgggcc cgttacggca tcaccggcca ccccgggagc
    11401 gtggtgccca ctccgggcac cgccgccgcc ctgtggggtg tggtgcacct cctgtgcgga
    11461 caaggcgacg agtgcatcct gctggacccc gtcgacctgc tgttcggcca agccgtcgac
    11521 gccgcggggg cccggcgggt ctactgcccg gtcgacaaga gcacggggct gctggacgcg
    11581 gaccggctcg cctcgctgat cacttcccgc accgccctga tctgcctgtg caatccgcac
    11641 aacccgctgg gcacggtctt cgacgagagg accctgcggg cggtggcgga gacggcgggc
    11701 aggcaccgga taccgatcct gtgcgacgag gtgtggaacg agatcgtcca cccgcccgga
    11761 cggcacatca gcatggcgag cctggagacc gggaacagcc ggcgcatcta cacggtgacg
    11821 ggcctgtcca agaccttcgc gctgccgggg ctgcggacgg gattcgtgct cgccccgacc
    11881 ccgcgggagg cggacgccct gcagctcacc ttccagcgcc tgggcgccgc gtacagcatg
    11941 acgcccttca gccaggccgg cgccctggcc gcgctgcgcc acggctggcc ctggaaggac
    12001 gccttcctgg aacacctgcg gggggtgcgg gactactgcg tggaccggct gaacgcgatc
    12061 ccgggaatca cctgcgggcg cccggaggga acctacgtcc tgttccccga tgtctccgcc
    12121 accgggctga gcagccgggc gatgggcggc ttcctgctgt cccgggcgcg ggtggcggtg
    12181 gtgcccggca cccccgagtg gttcggcccg gccgccgagg gcaacatccg catcagctac
    12241 gccacgtccc gggcggtcgt gcgggaggca ctggaccgca tcgcggaggc cgtcgaagaa
    12301 ctcgtcaccg gcggcccggc cgtactccag gccgccggga cggggcggta gagcgccggg
    12361 cgccaccgcc cccacccgga catcagccgt gcagccacgc cttgaacgag cgccaccagg
    12421 aggtacgcct cctgtgggcg ggaaccggcg ggggcgccac cggcgggaag ggcaccgagg
    12481 ggaacggcac cgacgggaac ggcacgcggg gcccggcagc gggtcccgaa ccgttgccgg
    12541 tggcgccgcg cgcggggtgc ccggccgtcg cggacgtcaa ggacgccgcg gccgtcgcgg
    12601 gggcagcggc cggaccggcg gacgcggcgg agtccgtggt ccgggacgcg gtgaacgtca
    12661 ccggaaggct ggccagatgc cgggtcatcc agcccgacgt ccagcgcagc tcctcctcgg
    12721 gaatgctcag ccgtacgtcg gggagccggg acagcagggc gtcgatgccg gtgtcggcga
    12781 tggcccggcc gatgttctgg ccgggacact cctggggacc gctgctgaag gcgaggtgcg
    12841 atcggttccc gtgcagcgga accgaagggt cgggccgtac ggccggatcg tagttcccgg
    12901 cggccaggca cagcagcagc atgtcccccg cctcgacctt ctgaccgccg acctcggtgt
    12961 ccacggcggc ccagcggccg gggacggtca tcaggggcgg ttcgctccac agcacctgct
    13021 ccaccacgtc gggcagggtc atctgcccgc cggccagcga cgcgtgacac cgggggtcgg
    13081 tcagcaccat ccgcagggtg ctcttgagca ggttgaccgt ggtctcgttc gcggcgatca
    13141 ggatgacccg caggtggttc cacacctcct cgtcggtcag ccccgaggag tggtcgatca
    13201 gccaggaggt gatgtcgtga ccccggctgc cgcgcttgcg ccgtacgaga tccgtgaggg
    13261 tctccacgat gaacgcgttg ctggccaccg aggtctcggt gcccgccacc atgtccctgc
    13321 tggccgcgac cagccgcggc ccgtactcgt cgggcatgcc caggagctgc gtcaggacga
    13381 gcatgggcag gtgttcgcag aactcctcgg ccaggtccgc ctccccccgc ccggcgaacc
    13441 cgtcgaccaa ttggtgtgtg aagcgggtga tgtgccgccg gataccgcgg cggttgaagc
    13501 gctccaggct ctcggtgacc gccaggcgca gccgggcgcg ctcctcaccg tccaggaaca
    13561 gacagaccgg ctgccaggcg atcatcggga gcagcgggga atccggcggc acccgccctt
    13621 ccttgaacca gcgccagttg cgggagtcgc ggctgaaccg ggcgggcgta ccggcgactt
    13681 cgaggatctc gcggtaaccg aggacgagcc aggccgggag gtcgccgtcc aggagaacgg
    13741 gtgcgacgga cccgtgccgg gcgcgcagac gctcgtacag gcccatgggg tcctcggccg
    13801 cctcggggcc gaagagccgc gccagtccgt ccgcggcgcc gaaccggtcg tgtgccgggc
    13861 actgcggagg gggagcggat gcccacgtgg tgcggggctg ttcggggaaa gaggaggtca
    13921 ccgtcgctcc ggggtcgtgg tggtgagggc gtgcagatag cgcacgagag tcagcagacc
    13981 ctcgcggctg gaagcgcgtt cgcgggcatc acagtcgatc accggcaccc cgtcggggat
    14041 gtccagggcc tcccgcagct cggacgccgg gtaacagggg gcgtccggga aggcgttgat
    14101 ggcgacgatg aagggcaccc cgcgctcttc gagccggccc atcacatcga agctgtcctc
    14161 cagccgccgg gtgtcgatca ggaccacggc gcccagcgct ccttcgaaga gcccgttcca
    14221 caggaaccag aaccgctgct ggcccggggt gccgaagacg tagagcacca gtttgtcgct
    14281 gagggtgatc cggccgaagt ccatcgcgac ggtggtctcg ttcttgcgct cgacaccggc
    14341 gatgtcgtcc acctcggcac cggcctgggt catgatctcc tcggtggtga gcggcttgat
    14401 ctcactgacc gatccgacca gggtggtctt cccgacgccg aagcccccga cgatcacgac
    14461 cttcaccgca gtggtgaccg aagccggcag ggcgtcttcg caccgggggc cgacgacggg
    14521 ttcggagagc ctgtagtcag agattttgta gtccatgcat caccgcctcc aagagttcca
    14581 cgtcgggcag cgactgggtc aggaccgacg cccgggcctc gacatgtccg ctcgccagga
    14641 gatccgtgag caagaggatg atcacgctga ccggcagatg gaggtacgcg gagatctcgg
    14701 ccacggacag cgggtagtcg catatgcgta ccacggcggc gagttcgggc tgcatgcccg
    14761 gaccggcctc gccgcggctg acgatcagtg tgaccatgtc caggcgggac tgccggtcgg
    14821 gcaggttccg gccggaggtg atgacgtaga gccgctcggg gccgccctct tcccaggcgc
    14881 gttgctgttc ttcctgctcc ggaccgctca tgggacctgc cggtcggcgc gcggtggcgt
    14941 ggtgaggtgc tggccgatcc gggcgaccag gtccctcatc cgctgcccca tgaggccggc
    15001 gtccacgtcg tcgtcggcca gcaccgccag ataggctccg gcgcctgccg ccatcagata
    15061 gaagaagccg ccgtcgacct cgaccacgac gagtttcatc cggccgtcac cccgcgggaa
    15121 ctccgcgccg atggccgccg acaggctctg cagtccggca caggcggcgg cgaggcggtc
    15181 agcggtgtcg ttgtccgcac cgaactgcgc catgcacaag ccgtccgagg acagcaccac
    15241 gacattacgg gtctgcggaa cgctggatgc caactcctcc agcatccagt ccatgttgag
    15301 ccgctgcttt gtcgccactt gctcactcat ccttactcgc tggctcggtc actgctcggg
    15361 ctcttcatcg cttggaccgt ggggacggtg cgccggggac ccgtccgcgg acgcgccgga
    15421 ggcaccgtcg aggaaggcgg acatccacag tccggccggt ggaggctggc cggccgacgc
    15481 cgggggacgg gagtcggccg cggaggccgc ctgctgcggc cgtacggacg ggatcacggc
    15541 gcgggtacgg cgcctgcgct gcggaagccc gttggcggta cgtgaacccg tggtgggtac
    15601 cggctcctcc atggcagcct cggcacggtg cttggggccg ctggggcggc ggggcggcgg
    15661 caggctcggc gccttggcca gggctccgcc gggcaccggg gtgacggtga tcaggtccgg
    15721 cggtacgacc aggaccacgc gtacgccgcc gtacgcggac acccgcaggg cgaccttgaa
    15781 gcggttggtg tgggacagcc ggccgaccac cgccaggccc aggcgcggcg attcccccag
    15841 gtcatcgagg tccagcccgc tggaggagtg ttgcgccaga gcccgttcgg cgcggatgcg
    15901 ggcctcgtcg gtcaggccga gcccggcgtc ctcgatctcg acggcgacac ccgactggac
    15961 ctcggtcgcg gtcagatgga cacgggtctg cggcggtgaa tagcgggtgg cgttgtccag
    16021 gagctcggcc acggcgtgga tcaggggctc ggccgcgcgg cccaggacac cgacgtcggc
    16081 caccgagtgc aggtcgacgc gctggtagtc ggtgatccgg gacatggctc cgcgcagcac
    16141 gttgaacagc gggatgtcct tctgccactg gcgccccggc cgggcaccgc cgagaacggc
    16201 gatgctgtcc gccagccgtc cgatcagcgc ggtgcggtgg tccaggtgca gcagatcgcc
    16261 gaacacctgc gggtcctgcc cgtgccggtc ctccatctcc cgcagttcca gggcctgttg
    16321 gtgcacgatg gcctggacgc gccgggcgat gttgacgaag gcccgctggg cggcgtcacg
    16381 caggtcctcc tcggcctcga cggcctggag gacgtagcgc agcaccgcgt ggtgtgcggc
    16441 ttcgaagccg gggctcaccc gggacacctg gcaggtgctg cgcagtacgt cctcgaccgg
    16501 catgcccttt tggagccggg ccatggccgc gggcagggtc tccttggcca tccgtagggt
    16561 ttcggcctcc tgctgggcca tctgccgttg caaggcggcc tcccgctcgg cgtactgcct
    16621 gcgcagctcg tcgatcgcac ggccccggcg cgctgccttc ccgcccgcga aggccaccgc
    16681 ggcggtcgcc acgacgccga tccagacggc atgggaacgg gccgccgtgg gcagcaacgg
    16741 aacggcgacg gccgcacata tggccaggag cgcgggtggc agcaaccaca ttgcggtgga
    16801 ggccggcccc ggccttccgg gtgacgaatc agcacgaacc atcggcatcc tcagagcact
    16861 aagggaaggg acagggagtc atacgcggaa ttcgcggaga tcaaaaggca gcggaaacgc
    16921 caggaatggc cgccggcgct gcgcggcagt gagcatagcg gggcacgaat ggctccgcgg
    16981 tgcatgtgca tacaacacat gaatgcactc acgtgcgaaa tcaagaagaa tcgtttggcg
    17041 ctagccgttc actggaatta cgaagagtcg tgacgattgc gagctgaatg cccgcattcg
    17101 cctatccgcc gcgccgtcgg tcgcatggag ttgcgaaatg tgatcagccc gtcccagaaa
    17161 ctgtccggga cgggctgagc tgggtcatgc cgtcttgaga gccgtgatga acgcggtcca
    17221 ggaggcggtc gggaaggtga gtatggggcc gtgggggttc ttgctgtcgc gtacggggac
    17281 gaggccgggc aagtcctcgg tgatctcgac gcagttaccc ccgttggcgt tgctgtagct
    17341 gctggcgcgc cagtgagcgg tactcacatc gggggagtga tgcatgactg atagtcctcc
    17401 atcgcctttc ggatcagttt cgccgactcc gcgggcgaaa gagcgatggc acgcagcacc
    17461 tcgtactgtc gccgccactt cttcaccgct tccggtacct cgtagagatg accggcttcg
    17521 atgccctcct cgtaggccac cgaggagccg ttggggagtg tcagcaaggt cagtgcaccg
    17581 ctcatcagcg tgtgcagtcc tgcgttgaag ggcaccactt gaaccttgct gtatggagta
    17641 tccacttgct ccaggagcga ggccagttgt tcgtacatgc attcttcgct gccggccggc
    17701 ctgcgcagca ccgactcgtc gatgatcgcc caccggtagg gaggggttgc cgagtactga
    17761 cgttcacgcc gggacagccg ggcagcgacc cgttcctcga tctgctcatc ggtccagcag
    17821 cccagactgc ggaacagcac ccgggcgtac gcctcggttt gaaggcaccc ggggacgacc
    17881 tgcggttcgt agttctcgat cgtttcggct tgtgcttcga ggtccatgaa gcgccggtac
    17941 tgatccggat gcacctcacg cttggcgagt tggtacaggt cgtagaagtg cttgccggtg
    18001 ccgaacgctg cgtccagtct gaccggcagg tcggagggcg gcatcagctc ggccgtttcg
    18061 atgcgggcca gggtgctctt gctggagttg acgatggcgg cgagctgtac gagggagagc
    18121 ttcgcggcct cgcggtggcg gcgttgttcg gagccgaagt agtggcgggc ggacacgtac
    18181 ggggtcaggg tccgggacgt gaacttcatg ggggagtcgc ctctctgccg tcccaatctc
    18241 aactgtggga cgagacgccc ctgttgagtc ccatgtcaca cggtgacgat ggtgatgcac
    18301 acggtagtca ccgggtgttc aggtgcgcca gagaggcaag gaagttcatg ttccatcgca
    18361 tcgcgcggtt cgccgtggcg ttgtcgcgcg gattgctgcc ggggaccggc cgccatcggg
    18421 cctgcggggc gccgcccgcc cgggccgggc ggtacgtgcc cgcggtccgg accccgcgcc
    18481 ggcgtcccga ggtcatgctg cgtggggagg cgagcgcgct ggtgaggccg tacacgctgt
    18541 cgccggagga gttccgtacg tggcggacgc gccgcgccgg ggcgggggcg cggtgagcgg
    18601 gggcgcgagg accgggcggc cgtccggtgc gccgttgcgt ctgctgccgt ggaccacacc
    18661 tatggggcag ccgtgctacc tcagtgcgga cgatccggag agtttgttgt ccttgctcgc
    18721 tgacgaggcg gaggaggaac tgcttgccgc cgccgagagt ctgctgtccg acgccgggcc
    18781 gctgcccgtg gtcgcggatc tggcggcgcc ggagctgcgg cgcgtgatcg cccgcttcga
    18841 ccgggcgctg cgtgatgtcc tgtgcatcgc ggtcagccgg ggcgcccggc tgatacaggg
    18901 cgaggcgccg ccatgtgagc acgggaccac cgagcagtgc gacggcaaga cgttctgctg
    18961 cggctgccgt cggcagatct atctgtgagg actgcggtgc gcgcgccggc ctcgtcgcag
    19021 ggcggcggtg gaggcacccg acggcgggcc gggtgcctcc accgcacctc gtgatcgata
    19081 catgatcaat acccctagcc ggtgaccttc acggtccagt cgcactcact gatgatctga
    19141 agctggtgag tgcccggcgt gtgctgctgg atgctgccct tgccggtctt gcccagctcg
    19201 ttgacgagct tgtcgttctt ctcgaacacg atgaagttgc ccttgccgtc gacggcagcc
    19261 atggccttgg tgcagtcgaa cgtgtacgac agcgtccact ccccgccgac catgaacgcg
    19321 ctggtgttct tggtgcggaa acccttgagg gcgaggaccg tggtcggctt ggccttgtgt
    19381 gtgggagtgg gagccgcctt gtgagacgcc tccgccgacg tcgaagccgg tgcgctcgcg
    19441 gccggcttgt ccttgtcgcc cttgtcgccc ttggcgctct tgtcgtcact tccgcaggcg
    19501 gagacggcgg cagcgaacac gatgacggcg agcgagccgc cgagtccccg cttgaaacgg
    19561 ccgttcctct tctcggccgg ctgccgccgg cccgccttcg gaccggtctt cggacggaag
    19621 tcggacaccc tcatcaccct gttcatctgc aaccgcgaaa ttccctggcg ccgcacggtg
    19681 cccacgccca ccgtgatcac acaaccatgg cgggcccatc catagggtgg acgggcccgc
    19741 catggtgcgg atggcttctg tgacgatggg cggacgcttg ccgtacggac gccaggtaaa
    19801 gggtccgggg tcgcgccgct tggccggacg catcgtaccg aagacccggc tcggcgagcg
    19861 gctccggtta cgggagggcg agcatgcgtt ccagggccag cttggcgaag ctctccgtct
    19921 ccgggtcgac ctggatgcgg ttgacgacct tgccggacgc cagggattcc agcgtccaca
    19981 ccaggtgggg gaggtcgatg cggttcatgg tcgagcagaa gcagaccgtc ttgtcgagga
    20041 agacgatctc cttgccctcc gaggcgaagc ggttggccag gcgccgtacg aggttcagtt
    20101 cggtgccgat ggcccacttg gagccggcgg gggcggcttc cagggtcttg atgatgtatt
    20161 ccgtggagcc gacgtagtcc gccgcggcga cgacctcgtg cttgcactcg gggtgtacga
    20221 gaacgttcac gccgggtatg cgggcccgta cgtcctccac ggactccagc gagaaccggc
    20281 cgtgcacgga gcagtggccc cgccacagga tcatcttggc cgcgcggagc tgctcggcgg
    20341 tcaggccgcc gttgggcttg tgcgggttgt agacgacgca gtcctccagg gacatgccca
    20401 tgtcccgtac ggcggtgttg cggcccaggt gctggtcggg gaggaagagc accttctcgc
    20461 cctgctcgaa ggcccagtcc agggcccgct tggcattgga agaggtgcag atcgtgccgc
    20521 cgtgcttgcc ggtgaacgcc ttgatgtcgg ccgaggagtt catgtacgag acggggacga
    20581 cctgctcggc cacgccggcc tcggtcagta cgtcccagca ctcggcgacc tgctcggcgg
    20641 tggccatgtc ggccatcgaa cagccggcgg ccaggtcggg caggacgacc tgctgctcgt
    20701 cggtggtcag gatgtccgcg gactcggcca tgaagtgcac accgcagaag acgatgtact
    20761 cggcgtccgg ccgggccgcc gcgtcacgcg cgagcttgaa ggagtccccg gtcacgtccg
    20821 cgaactcgat gacctcgtcg cgctggtagt ggtgaccgag gatgaagacc ttgtccccga
    20881 gcttctcctt ggccgcgcgg gcgcgctcca ccaggtcggg gtcggacgga gccggcaggt
    20941 caccggggca ctccacgccg cgctcactct tggggtcggc ctcgcggccg agcagcagca
    21001 gggccagcgg ggtcggctgg acgtccaggg gctgggcggt ggtcacgaca cgcaccctct
    21061 ctttgcgtcg gtggttgcac cggacctttt cgtcggtttg acgttat
//
