LOCUS       NZ_CP074380            25128 bp    DNA     linear   CON 27-MAY-2024
DEFINITION  Streptomyces sp. MST-110588 chromosome, complete genome.
ACCESSION   NZ_CP074380
VERSION     NZ_CP074380.1
KEYWORDS    RefSeq.
SOURCE      Streptomyces sp. MST-110588
  ORGANISM  Streptomyces sp. MST-110588
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1  (bases 1 to 7915503)
  AUTHORS   Booth,T.J., Bozhueyuek,K.A.J., Liston,J.D., Lacey,E. and
            Wilkinson,B.
  TITLE     Bifurcation drives the evolution of assembly-line biosynthesis
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 7915503)
  AUTHORS   Booth,T.J., Bozhueyuek,K.A.J., Liston,J.D., Lacey,E. and
            Wilkinson,B.
  TITLE     Direct Submission
  JOURNAL   Submitted (10-MAY-2021) Molecular Microbiology, John Innes Centre,
            John Innes Centre, Norwich, Not US or Canada NR4, United Kingdom
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: 28-FEB-2016
            Assembly Method                   :: HGAP v. 3.0
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 25.0x
            Sequencing Technology             :: PacBio RSII
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_022695595.1-RS_2024_05_27
            Annotation Date                   :: 05/27/2024 05:38:09
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 6,918
            CDSs (total)                      :: 6,828
            Genes (coding)                    :: 6,327
            CDSs (with protein)               :: 6,327
            Genes (RNA)                       :: 90
            rRNAs                             :: 7, 7, 7 (5S, 16S, 23S)
            complete rRNAs                    :: 7, 7, 7 (5S, 16S, 23S)
            tRNAs                             :: 66
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 501
            CDSs (without protein)            :: 501
            Pseudo Genes (ambiguous residues) :: 0 of 501
            Pseudo Genes (frameshifted)       :: 350 of 501
            Pseudo Genes (incomplete)         :: 185 of 501
            Pseudo Genes (internal stop)      :: 14 of 501
            Pseudo Genes (multiple problems)  :: 45 of 501
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 12:56:23
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 2454684
            Orig. end                         :: 2479812
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP074380.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            Bacteria and source DNA available from Barrie Wilkinson, John Innes
            Centre, Norwich.
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..25128
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="triceptide"
                     /region_number="15"
                     /rules="((cds(PF04055 and (TIGR04085 or SPASM)) and
                     triceptide_precursor) or triceptide_rSAM)"
                     /tool="antismash"
     cand_cluster    1..25128
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="((cds(PF04055 and (TIGR04085 or SPASM))
                     and triceptide_precursor) or triceptide_rSAM)"
                     /kind="single"
                     /product="triceptide"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..25128
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:15128](-)"
                     /cutoff="5000"
                     /detection_rule="((cds(PF04055 and (TIGR04085 or SPASM))
                     and triceptide_precursor) or triceptide_rSAM)"
                     /neighbourhood="10000"
                     /product="triceptide"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..15128)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="5000"
                     /detection_rule="((cds(PF04055 and (TIGR04085 or SPASM))
                     and triceptide_precursor) or triceptide_rSAM)"
                     /neighbourhood="10000"
                     /product="triceptide"
                     /protocluster_number="1"
     misc_feature    complement(45..60)
                     /note="TFBS match to ClgR, Caseinolytic protease gene
                     regulator, confidence: weak, score: 22.07"
                     /tool="antismash"
     misc_feature    48..63
                     /note="TFBS match to ClgR, Caseinolytic protease gene
                     regulator, confidence: medium, score: 24.85"
                     /tool="antismash"
     gene            185..946
                     /locus_tag="KGS77_RS10675"
                     /old_locus_tag="KGS77_10565"
     CDS             185..946
                     /GO_function="GO:0008168 - methyltransferase activity
                     [Evidence IEA]"
                     /GO_function="GO:0008757 - S-adenosylmethionine-dependent
                     methyltransferase activity [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1089: methyltransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014176890.1"
                     /locus_tag="KGS77_RS10675"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KGS77_10565"
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="WP_242587406.1"
                     /transl_table=11
                     /translation="MTGTARARSFDRAAGRYGASRPSYPPALLDAVEEFMGRPLAGARV
                     ADVGAGTGIATALLCGRGAEVVAVEPGDGMAAEFREALPGVPVVRGDGNALPLADASHD
                     LITYAQAWHWTDTGRSVPEALRVLRPGGALAVWWNTHALDVPWIAAQRDRVARHCGVQP
                     PSAARPDDGRAVRLAGFTGLRTARRQVRWSRTVPLDTHLENLGSHSAFLVLGEAGTRAF
                     LAEERGRLREIFPAGTVEETYVADLLVAFRP"
     gene            complement(995..1309)
                     /locus_tag="KGS77_RS10680"
     CDS             complement(995..1309)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="KGS77_RS10680"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_242580543.1"
                     /transl_table=11
                     /translation="MIRSVPTEEKKEKGEEGEEEKEEKEEKDTRHFLVVFERPGRSPIL
                     RDHDPAKGMLTKLLASHIHQPPLPVPTSRSVPSWLRRRAVTLRTRGRSVALRTPGQSNV
                     "
     gene            1320..1799
                     /locus_tag="KGS77_RS10685"
                     /old_locus_tag="KGS77_10570"
     CDS             1320..1799
                     /GO_function="GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1111: GCN5-related N-acetyltransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016645453.1"
                     /locus_tag="KGS77_RS10685"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KGS77_10570"
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="WP_242580544.1"
                     /transl_table=11
                     /translation="MLRPWTPEEIAAVVGDERSEHWAEDFPADGDRVIAGFVAGHPDGP
                     AGSGQRQILERESGLVVGSIGLFRPAREGVVEFGYGVVASRRGRGYASEAARAIVEFAL
                     DAPEVHTVRADVELGNPASIRVLEKAGLRRRVQDATTARYQITAQEFARLSAGPS"
     gene            complement(1756..2643)
                     /locus_tag="KGS77_RS10690"
                     /old_locus_tag="KGS77_10575"
     CDS             complement(1756..2643)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006603141.1"
                     /locus_tag="KGS77_RS10690"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KGS77_10575"
                     /product="rhomboid-like protein"
                     /protein_id="WP_242580545.1"
                     /transl_table=11
                     /translation="MAATEADAAGKNDRPLLAGIPAPEHASPIEQVSAPGQASPPEHAS
                     PPDPGLASVSGLVPDSGFVSASGLVHDPGLAPASGLAPWRPGRLLPTPTGAPFTFCYAL
                     LLAATTVFAENADPALVLDLLRGSSTDVQHLAHAPLLALLTSALWSAGGLLSAYALAFP
                     FVLTALERRVGSLRTAAVFFGGHAIATLATEVPVGLSVALGQLPGSALHRLDYGISFGV
                     MTCVGALAVLLPPWGRLPLLFAAGALAVSDLLAYLDPVSDWGHLLSLTLGAASGALLRR
                     VRRVRQTAVRTPAP"
     gene            2957..3730
                     /locus_tag="KGS77_RS10695"
                     /old_locus_tag="KGS77_10580"
     CDS             2957..3730
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018959057.1"
                     /locus_tag="KGS77_RS10695"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KGS77_10580"
                     /product="spermidine synthase"
                     /protein_id="WP_242580547.1"
                     /transl_table=11
                     /translation="MAPVPSVYPPQVHPRPDQAGQENEQDAPDAPDAYDGPRVLDRREG
                     PYGEVVLRQRGEHFEIIANGCFLMDTSDGRSERLLIDAALAALPAGRERPALLIGGLGV
                     GFSAVRAAAEPRWGRIVVVEREDAVVDWHRTGPLATLSAPALADPRTEIAPADLLTYLR
                     EDTGPDAFDALCLDIDNGPDWTVTEDNGGLYSPAGLALCRDRLTPGGVLAIWSAQPSSD
                     FETSLRNAGFTGVRTEEVPVARGVPDVVHLAHKGA"
     gene            3890..4630
                     /locus_tag="KGS77_RS10700"
                     /old_locus_tag="KGS77_10585"
     CDS             3890..4630
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1008: response
                     regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018536131.1"
                     /locus_tag="KGS77_RS10700"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KGS77_10585"
                     /product="response regulator transcription factor"
                     /protein_id="WP_242587407.1"
                     /transl_table=11
                     /translation="MDQTQTTQGGTAAATPGAQRRILVVEDDPTIVDAIATRLRAEGFQ
                     VQTATDGPAAVDTAEAWQPDLLVLDVMLPGFDGLEVCRRVQARRPVPVMMLTARDDETD
                     MLVGLGVGADDYMTKPFSMRELAARVHVLLRRVERAALAAHTPRSGILRLGELEIDHAQ
                     RRVRVRGEDVHLTPTEFDLLVCLANTPRAVLSREQLLAEVWDWADASGTRTVDSHIKAL
                     RRKIGAERIRTVHGVGYALETPPA"
     gene            4744..5801
                     /locus_tag="KGS77_RS10705"
                     /old_locus_tag="KGS77_10590"
                     /pseudo=""
     CDS             4744..5801
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1003: sensor
                     histidine kinase"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018536132.1"
                     /locus_tag="KGS77_RS10705"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /old_locus_tag="KGS77_10590"
                     /product="ATP-binding protein"
                     /pseudo=""
                     /transl_table=11
                     /translation="MRPLDPYRSVKAALGALVIVSVIITTLLIFVAIHSATELRIITVF
                     SVIASLLVTQFVAQSLTAPLDEMTDVTRSMANGDYTRRVRAERRDEFGDLADAFNRMAA
                     DLEAVDTHRKELVANVSHELRTPIAALRAVLENVVDGVCRPDPETMRTALKQTERLGRL
                     VEHLLDLSRLDNGVVPLHARRFEVWPYLSGVLKEANMSRGAATLAGSGTHTRTDVHLHL
                     DVSPPELTAYADAERLHQVVANLIDNAIKHSPRHGRVTVRARRGAGPESLELEVQDEGP
                     GVPESERHRVFERFNRGGPGPSGPGTDGGTGLGLAIARWAVDLHGGRIGVAESPVAAAS
                     ASPFRGSTPREA"
     misc_feature    4761..4774
                     /note="TFBS match to BldD, Development and antibiotic
                     global regulator, confidence: weak, score: 19.18"
                     /tool="antismash"
     misc_feature    4773..4782
                     /note="TFBS match to AbrC3, Antibiotic production
                     activator, confidence: strong, score: 18.16"
                     /tool="antismash"
     gene            6041..9895
                     /locus_tag="KGS77_RS10710"
                     /old_locus_tag="KGS77_10595"
     CDS             6041..9895
                     /EC_number="4.1.1.71"
                     /GO_function="GO:0004591 - oxoglutarate dehydrogenase
                     (succinyl-transferring) activity [Evidence IEA]"
                     /GO_function="GO:0016746 - acyltransferase activity
                     [Evidence IEA]"
                     /GO_function="GO:0030976 - thiamine pyrophosphate binding
                     [Evidence IEA]"
                     /GO_process="GO:0006099 - tricarboxylic acid cycle
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018102698.1"
                     /locus_tag="KGS77_RS10710"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KGS77_10595"
                     /product="multifunctional oxoglutarate
                     decarboxylase/oxoglutarate dehydrogenase thiamine
                     pyrophosphate-binding subunit/dihydrolipoyllysine-residue
                     succinyltransferase subunit"
                     /protein_id="WP_242580549.1"
                     /transl_table=11
                     /translation="MSPQSPNSSSNSTDQEGQGKNPAAAFGPNEWLVDEIYQQYLQDPN
                     SVDRAWWDFFADYKPGAGATAPSSASEGSPATQATGTAPAAPGAAAPSAPAAPAAQQPA
                     PPAAEPAAARPAAPARPAASAPAPAQAAPAQAAPAKTAPVKTAQPAAKKDDVKADEAPA
                     GPELVTLRGPSAAVAKNMNASLELPTATSVRAVPVKLLFDNRIVINNHLKRARGGKVSF
                     THLIGYAMVQALKAMPSMNYSFTEKDGKPTLVKPEHVNLGLAIDLVKPNGDRQLVVAAI
                     KKAETLSFFEFWQAYEDIVRRARNNKLTMEDFTGVTASLTNPGGIGTVHSVPRLMPGQG
                     LIIGVGAMDYPAEFQGTSQDTLNKLGISKVMTLTSTYDHRVIQGAASGEFLRIMNQLLL
                     GENDFFDDIFKSLRIPYEPVRWLRDIDVSHDDDVTKAARVFDLIHAYRVRGHVMADTDP
                     LEYEQRKHPDLDIIEHGLTLWDLEREFAVGGFAGKSMMKLRDILGVLRDSYCRTTGIEF
                     MHIQDPKQRKWIQDRVERGHSKPEREEQLRILRRLNSAEAFETFLQTKYVGQKRFSLEG
                     GESVIPLLDAVIDSAAEARLDEVVIGMAHRGRLNVLANIVGKSYAQIFREFEGNLDPKS
                     MHGSGDVKYHLGAEGTFTGLDGEQIKVSLTANPSHLEAVDPVVEGVARAKQDIIGKGGT
                     DFTVLPVQLHGDAAFAGQGVVAETLNMSQLRGYRTGGTVHIVINNQVGFTAAPESARSS
                     MYATDVARMIEAPIFHVNGDDPEAVVRVARLAFEFRQAFNKDVVIDLICYRRRGHNESD
                     NPGFTQPLMYDLIDKKRSVRKLYTESLIGRGDITLEEAEQALQDFQGQLEKVFTEVREA
                     TTAPAAPEVPQPQAEFPVHVDTAVSQEVIKRIAESQVNIPERVTVHPRLLPQLQRRAAQ
                     VEDGTIDWGMGETLAIGSLLMEGTPVRLAGQDSRRGTFGQRHAVLVDRRTGEDYTPLLY
                     LSEDQARFNVYDSLLSEYAAMGFEYGYSLARPEALVMWEAQFGDFVNGAQTIVDEFISS
                     AEQKWGQTSGVTLLLPHGYEGQGPDHSSARIERFLQLCAQNNMTVAMPTLPSNYFHLLR
                     WQVHNPHHKPLVVFTPKSMLRLKAAASKTEEFTTGGFRPVIGDGTVDATAVRKVIFCSG
                     KVYYDLEAERAKRGANDTAIIRIERLYPLPGRELQAEIAKFPNAGKYLWVQEEPANQGA
                     WPFLGLNLIDHLDLAVGADIPHGERLRRISRPHSSSPAVGSAKRHQAEQAQLVAEAFDA
                     "
     gene            complement(10001..10231)
                     /locus_tag="KGS77_RS10715"
                     /old_locus_tag="KGS77_10600"
     CDS             complement(10001..10231)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     triceptide: triceptide_precursor"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF041709.1"
                     /locus_tag="KGS77_RS10715"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KGS77_10600"
                     /product="YxD-tail cyclophane-containing RiPP peptide"
                     /protein_id="WP_242580551.1"
                     /sec_met_domain="triceptide_precursor (E-value: 1.0,
                     bitscore: 10.0, seeds: 0, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSDSGTGGAPVTEARRDAAPREEALPDFGRPDLAGLRQRVGHPVL
                     TEVVAVLEERAHGDAAPVAYYDDGPGPDVGR"
     gene            complement(10270..13269)
                     /gene="fxsT"
                     /locus_tag="KGS77_RS10720"
                     /old_locus_tag="KGS77_10605"
     CDS             complement(10270..13269)
                     /codon_start=1
                     /gene="fxsT"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018087458.1"
                     /locus_tag="KGS77_RS10720"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KGS77_10605"
                     /product="FxSxx-COOH system tetratricopeptide repeat
                     protein"
                     /protein_id="WP_242580553.1"
                     /transl_table=11
                     /translation="MVDQPTTTGSNEHITISYAGFNRPWAAWISHQLEQLGHGTTMLRW
                     DPSANSPLTEELAGLLAAEGRLLMVLDDWYFRLGPKTHEEWTAALQEVVAPHVERFAAV
                     SVATQRLPSTASILRPADLRDLDAVEANRRVLHRLGVDPGRRRAEDAVTNAPRFPNDPP
                     EVWNIPRRNNRFTGRDNVLEDLHGKLAGGLGSGPPLETRIALYGISGVGKSQIAAEYAH
                     RFGNDYDVVWWISATNRGAAREQLAELATRLNLPVGQELGDRIRAVHEALRIGRPYRRW
                     LLVFDSADDMEQIEDLVPDGRGHVLITTLTRDWSGSGSAQEIEVLPFTRTESVAYARRR
                     APRLTPMEADLLAEAVQDLPLLLAQTAAWLDANPMSPKEYIELIRRGEPSLVGIRISSD
                     YPMAFQTSWAITLNTLRERSPAAVELLKLFAFFAPEAIPVPMLAKARRGDLPEHLADLA
                     AEPISWNTALRRLTESTAVRLDYQVSQTFDPAVETAQMHRLYHRFLRSDMSEDERDRMS
                     ATACRVLVSADPQVPSDTRYWERYAELIPHLEPAGVLDSPEQSVQEMLLNCIEYLRVRG
                     EYRIGLKLCEQFLSRWRTRIRPTQRTMLILTHQHANMLRWLGRYREAEAVGSAIVDQLS
                     AEREAIDADLLRAQDGLAGTLMALGSYEEAFALFDTVWRAYVELLGAEAPRTLSCRVNR
                     GAALGMLGRYEEALVTYREVLAIRERELRARHHLTLNAGTSYARMLRLLGHYRDAASRQ
                     DLNARLHHQVMGPHNPQTLRADHNLALCLRRAGDLSHADSLMADVMERSQRVQGPRHPE
                     TLMVRADYATFLREHGDLGHARELAEEVAERYRTLAGEDHPYTVGTLGNTGLVRGEFGE
                     VSEALDIAERALSGMRRAVGPDHPWTLGCALNASGARNRADDEEGAVELSRDTMERAKT
                     VLGETHPLTLSAKTGLAEDLRALRRGQEAAKLEQEAVQQLTETLGPEHPHTLSARRRRR
                     PYWDFEPQPV"
     gene            complement(13434..14594)
                     /locus_tag="KGS77_RS10725"
                     /old_locus_tag="KGS77_10610"
     CDS             complement(13434..14594)
                     /GO_function="GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA]"
                     /GO_function="GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     triceptide: triceptide_rSAM"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PTHR43273"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) SAM_SPASM_FxsB"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF04055"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018521086.1"
                     /locus_tag="KGS77_RS10725"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KGS77_10610"
                     /product="FxsB family cyclophane-forming radical SAM/SPASM
                     peptide maturase"
                     /protein_id="WP_242580555.1"
                     /sec_met_domain="PTHR43273 (E-value: 1.6e-83, bitscore:
                     279.5, seeds: 35, tool: rule-based-clusters)"
                     /sec_met_domain="SAM_SPASM_FxsB (E-value: 1.1e-128,
                     bitscore: 427.8, seeds: 10, tool: rule-based-clusters)"
                     /sec_met_domain="PF04055 (E-value: 5.7e-13, bitscore: 48.2,
                     seeds: 518, tool: rule-based-clusters)"
                     /sec_met_domain="triceptide_rSAM (E-value: 1.0, bitscore:
                     1.0, seeds: 0, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MECETDRTIRVPFRQFVLKVHSRCNLACTYCYIYQSPDASWRDRP
                     RRVAPATMRRTALRIAEHVRAHRLAGIRVDLHGGEPLLTGPGPLLEQAAAVRAVLPEGC
                     AAAFGVQTNGTLLTDPVLDTLADAGFRVGLSLDGGTPVLNRRRVDHAGRPSWPDVSRAA
                     RLLARRPEVFAGVLCTIDITSDPAEVYHSLRALNPPMLDFLLPHANWSSPPPAPPGAPG
                     PTPYGDWLCTVFDLWWEEPPGAPRVRGFTEIIGLLLGRPSSSEAVGLSPVVALVVDTDG
                     AIEQVDSLKSTYDGAAATGLDVFRNTFDEALDHPGMAARQQGALSLGAQCRGCALMEVC
                     GGGNYAHRYRADGSGFRNPSVYCADLERLIRHIAGRLSAAVAGAPR"
     misc_feature    complement(14638..14651)
                     /note="TFBS match to LexA_variant_2, Repressor of DNA
                     damage response, confidence: weak, score: 17.8"
                     /tool="antismash"
     gene            complement(14877..15128)
                     /locus_tag="KGS77_RS10730"
                     /old_locus_tag="KGS77_10615"
     CDS             complement(14877..15128)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     triceptide: triceptide_precursor"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003986810.1"
                     /locus_tag="KGS77_RS10730"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KGS77_10615"
                     /product="YxD-tail cyclophane-containing RiPP peptide"
                     /protein_id="WP_242580557.1"
                     /sec_met_domain="triceptide_precursor (E-value: 1.0,
                     bitscore: 10.0, seeds: 0, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MVTIALTGPAPVRPPGPSAEPLPDFGGVDVASVAEHSGHPVLGAV
                     AALLLSNWPAADEAVAYYEDGPGDPGEVFDPGKLPVTS"
     gene            complement(15203..18520)
                     /locus_tag="KGS77_RS10735"
                     /old_locus_tag="KGS77_10620"
     CDS             complement(15203..18520)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018087461.1"
                     /locus_tag="KGS77_RS10735"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KGS77_10620"
                     /product="SAV_2336 N-terminal domain-related protein"
                     /protein_id="WP_242580559.1"
                     /transl_table=11
                     /translation="MPAGEPGHGPLDQLVARLRAAGLPADARAMADALWLAQWITPGGQ
                     PEPAPPDDRDDVNGQDRRKPATFSVGGQRREPARDSPRLTESASRPTRRDVDLLPSQGD
                     HGPDPDRHGLGEVGVPVASAFPGLLPLQRALRPVQRYRPPVAPARQELDETGTAELSAH
                     AEMLIPVFRGIHRREAALRLFMDGSASMAIWEQMVHDLRQVCERVGAFRDVTVHYLHPY
                     GKDVGVAAGPAPGDPLRPADQLHDPTGHHLTLVVSDCAGPLWEDGRMQRLLYRWVADAP
                     VAVVQPLPQRMWARTFLPAVPGTLIRHQGPYGDLGFEPARRRRRAAGAPGEGYRPARER
                     VVPVLSAAPAALGTWARLAAAESGLSLRGAACTVRADHGLGAVPPPQPGTADPLELIGE
                     FDRTASPAARHLAVHLSAVPLALPVIQLVQRAMLPQTGPAELAEVLLSGLVVQLPAPER
                     PAGPEAEAAGPWYDFVPGVRDELLGRLSAGEAALVLKHCSLYIERTFGRSARNFPAVAV
                     AMLCGSGREPETGRRAVPEPFARISERVLRRFEPAIKPPVPQVYATDGPAAQGAAYLER
                     YEQDGAVRDLVEAVRLLRAAAQRLPEAGTDLARALLHAWAQLRQPDALEEAERAVRAAE
                     EAAAGVGSGHDEDGEARLRALIVLARVRYAGAQERRAASAVSGERAALEDAALHLESAC
                     GLMSLLDDRVLECMVLRTEVLRRLAALAPDPPPSGVAWPPRAAHDPLKEAEGALTTLLE
                     RWPSGEQVPGEIYAARGGVFLDQARRAARDTTDDGRRTGPLALRATADLDTATVLLRRR
                     GATADRMICESLLELAEARTLLVFDDQALPTVLRTLERARALAHELRDPALEADSLART
                     AAAHRTVHARTGDLTALDAAIDALAAALRLTTPDTPEHSSLLAERGAALLTRARLEPAA
                     EPGKRMANEAVHVLREALARVAPQDPGLGAHRLLFGRALRLRYERQPSLADLHEADWIL
                     ELAARGSDDPAVSAEAWLEVGDVQLLLDRRFDSMERHDRAAACYRRAATDAQRADNPLL
                     AARAHHRRGEVLEDTAGKQSALQAYEESWAQWQRASEENGPEARRTRDRMRALVATD"
     misc_feature    complement(17420..17422)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            complement(18525..19601)
                     /locus_tag="KGS77_RS10740"
                     /old_locus_tag="KGS77_10625"
     CDS             complement(18525..19601)
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006603151.1"
                     /locus_tag="KGS77_RS10740"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KGS77_10625"
                     /product="MoxR family ATPase"
                     /protein_id="WP_242580561.1"
                     /transl_table=11
                     /translation="MSDWLIYRGAGAPHDGIEQLPPPPPWRDFDGEPLVAPPAALDHAS
                     ERRLGVLSREASYHRPGETERELVNAALYLRRPLLVTGAPGSGKSTLAHSVAYELGLGR
                     VLNWPIVSRSTLRDGLYQYDAIGRLQDLQIARAVPPRPPLGPDAAAPDALPGEAPEEEP
                     GGGIGRYIRLGPLGTALLPAAKPRVLLVDELDKSDIDLPNDLLNVLEEGEFTIPELERL
                     SASAPEVPVLSDDGTRVRVRNGRVRCRAFPFIVLTSNGERDFPAPLLRRCIHLNIPTPN
                     KERLAGMVRAHFGEDAAERYESVIDRFLDREPGDVRAVDQLFNAIHLTQKAGWTDEDEE
                     ETRRRLTAELMRPLDRTR"
     misc_feature    complement(19140..19142)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            complement(19806..22076)
                     /locus_tag="KGS77_RS10745"
                     /old_locus_tag="KGS77_10630"
     CDS             complement(19806..22076)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006603152.1"
                     /locus_tag="KGS77_RS10745"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KGS77_10630"
                     /product="serine protease"
                     /protein_id="WP_242580562.1"
                     /transl_table=11
                     /translation="MATSEGRDRADREKYAQLLEQAGRATVGIRAAPGAGPGPLWGSGV
                     FIAPGWVLTCAHVLVSSDGRRRETGKDGEIGVVFEGRVAGARLEYDLSRPAGGAGRAGG
                     PGRPDLALVRLLEPYPEHRCAWLSDQHAALLEDAYIFRGHDQLGGSGAWGACGHAGAPG
                     DARDSGDAHDPGGAYDPGDAYDSAGAYDSGGAYGQGGAYGRGGVYVPGGAHGPGRAPIE
                     AGVRQAPVDPFIAVRFGARDARGLQFGSDVRVTPGASGGPLLDCDRGEVVGIVKGRHQE
                     DKVGLAVPVTALRALGPQHLLPGRTGLGPDPYHELMSLHDRWHWAGQDLGRRGEPTWFD
                     AQYAIMAGRERLWGVAERLQALDLLARLPAPRDPLVVEAAVCEVLGGRDRAGTWSLRTW
                     RDGHGVLYQGSDPYSERCAFVHYLRIVAQRTSEEVRGVPGEEAARVREAAERLARFVTD
                     KAAVLLPKDRRRIGPVPRRPDAVLVEFEPLFYGDGGQQLFNWSVSEGYGRGEWMRVDLQ
                     ESEGGMTFEQAQAQVLRRLGPRLLRADGDVGPGGRVRLEVAVPEGYWQLPADRWAVPVS
                     TRAGARARPIGSGRPVVLRDQGRRQAVDPAWLRRWRGLMGAPELSALRVPPRAGGGPES
                     VWRLLENGEEGAVPTLCRSVAVGTGLDAVGAALDAGYPVSLWLSEGHDERECDSACDDF
                     HREVRDLLAAKGVTALPELVRELRGRAEETSAHWARDLVLLYDDPDNPIPQLFAGGPQL
                     SSR"
     misc_feature    complement(21171..21173)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            complement(22076..22465)
                     /locus_tag="KGS77_RS10750"
                     /old_locus_tag="KGS77_10635"
     CDS             complement(22076..22465)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006603153.1"
                     /locus_tag="KGS77_RS10750"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KGS77_10635"
                     /product="CU044_2847 family protein"
                     /protein_id="WP_242580563.1"
                     /transl_table=11
                     /translation="MRDRVGRIALPDGTEVWARVSRLEVPLPGETGEDDEFEDVGAWEA
                     LTTRVEGLRELIGGVATSVREAAQRVAPHETSVTFGVEVSAKPGKAVALLADGEAKANL
                     SVTLTWRREPDTAGGDGQGTGDSGT"
     misc_feature    22622..22637
                     /note="TFBS match to ColR, Phenol-responsive regulator,
                     confidence: weak, score: 17.25"
                     /tool="antismash"
     gene            22627..22803
                     /locus_tag="KGS77_RS10755"
                     /old_locus_tag="KGS77_10640"
     CDS             22627..22803
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006603154.1"
                     /locus_tag="KGS77_RS10755"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KGS77_10640"
                     /product="DUF6104 family protein"
                     /protein_id="WP_242580564.1"
                     /transl_table=11
                     /translation="MYFTDRGIEELESRRGDEEVTLGWLADQLRTFVDLNPDFEVPVER
                     LATWLARLDDEDE"
     misc_feature    complement(22673..22688)
                     /note="TFBS match to AfsQ1, Two-component system AfsQ1-Q2,
                     activator of antibiotic production, confidence: weak,
                     score: 16.94"
                     /tool="antismash"
     gene            22974..23903
                     /locus_tag="KGS77_RS10760"
                     /old_locus_tag="KGS77_10645"
     CDS             22974..23903
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018087466.1"
                     /locus_tag="KGS77_RS10760"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KGS77_10645"
                     /product="DUF4097 domain-containing protein"
                     /protein_id="WP_242580565.1"
                     /transl_table=11
                     /translation="MSARSEWSVTEPRTLEIEEPVRELDVRVVSGTVNVVGVPAGSVPG
                     SGAARVEVTALHGPPLTVSCRDGVLSVGYKDLPWKGWLDFGKLKGWRRTAVVSVTVPAA
                     TGVRVGVVGAGAVISGISGRTQLNGVSGGSTLVGLTGPVRAETVSGDVQAQAVTGDLRF
                     SSVSGDLTVVDGAGASVRAESVSGDMVLDLDLPPAAGPGGTGRTDVKLTTVSGEVAIRL
                     PDPADAQVDAQVEANTTSGTVANAFEDLRVSGQWGAKRITGRLGAGNGRLEVTTVSGGL
                     ALLRRPPSHDGPVRHGDTDETPADKKVL"
     gene            23907..>24768
                     /locus_tag="KGS77_RS10765"
                     /pseudo=""
     CDS             23907..>24768
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1278: PadR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006603156.1"
                     /locus_tag="KGS77_RS10765"
                     /note="frameshifted; incomplete; partial in the middle of a
                     contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /product="helix-turn-helix transcriptional regulator"
                     /pseudo=""
                     /transl_table=11
                     /translation="MPPVFAHGRLRLYLLKLLDEAPRHGYEIIRLLEERFQGLYAPSAG
                     TVYPRLAKLEAEGLVTHTTEGGRKVYSITDAGRAELADRGGELAELELEIRESVAALAS
                     DIREDVSGSVRDLRREIREAAQRTRKESRAGAGAGAAGGRGRRRRRGPYGRGPYGRGRG
                     RRRRAG"
ORIGIN
        1 gtacccactc aatgctcctg agccaccgga tgttccccgt cccgtgttcg ctgtgagcga
       61 tcagacggcc agaacggaac gggtcggggt cgaggatgag gagatgactg ggaccactgg
      121 gtcggacggg ctggacgggt cgactgggat gaacgggacg actgacatga ccgggacgac
      181 tgacgtgacc ggcacggcgc gggcgcgttc gttcgacagg gctgccgggc ggtacggggc
      241 gagccgccct tcgtatccgc ccgcccttct ggacgccgtc gaggaattca tgggacgccc
      301 gctggcgggg gcccgggtcg ccgacgtggg ggcgggcacc gggatcgcca ccgccctgct
      361 gtgcgggcgc ggtgccgagg tggtcgcggt ggagcccggt gacggcatgg cggcggagtt
      421 ccgcgaggcc ctccccggcg tgccggtcgt ccggggtgac ggcaacgccc tgccgctcgc
      481 cgacgcctcc catgacctga tcacgtacgc gcaggcgtgg cactggaccg acaccggccg
      541 ctccgtcccc gaagcgctgc gcgtgctgcg cccgggcggg gcgctggcgg tctggtggaa
      601 cacccacgcc ctggacgtgc cgtggatcgc cgcgcagcgg gaccgggtcg cgcggcactg
      661 cggggtgcag ccgccctcgg cggcccgtcc tgacgacggg cgtgccgtcc ggctcgccgg
      721 cttcaccggt ctgcgcaccg cccgccgcca ggtgcgctgg agccgtaccg tcccgctcga
      781 cacgcacctg gaaaacctcg gcagccattc ggcgttcctc gtcctcggcg aggccggtac
      841 ccgtgcgttc ctcgccgagg agcgggggcg cctgcgggag atcttccctg cggggacggt
      901 ggaggagacg tacgtggccg acctgctggt cgccttccgc ccctgagatt cctgagattc
      961 ctggggttcc tggggtttct gagccggatg cgggtcaaac gttcgactgc ccgggtgtac
     1021 ggagtgctac gctccggccg cgcgtgcgga gcgtgacagc gcgacgccgc agccacgacg
     1081 gcacggaccg cgaggtcggg acgggaagag ggggttgatg aatatggctc gccaagagct
     1141 tcgtcagcat gcccttggcc gggtcgtggt cgcgcaggat tggtgagcgg cccggtcgtt
     1201 cgaaaacgac caggaagtgt cgcgtgtctt tttcttcttt ttcttctttc tcctcttccc
     1261 cctcctctcc tttctctttc ttctcttcgg tcggtacgga tctgatcacc gatcggcttg
     1321 tgctgcggcc ctggaccccc gaggagatcg ccgccgtggt cggcgacgag cggtcggagc
     1381 actgggccga ggacttcccc gccgacgggg accgggtgat cgccggtttc gtcgccgggc
     1441 atcccgacgg acccgcggga agcgggcagc gtcagatcct ggagcgggag agcggcctgg
     1501 tggtcggttc catcggtctg ttccggccgg cgcgggaggg ggtcgtggag ttcgggtacg
     1561 gcgtcgtcgc ctctcgcagg gggcgcggtt acgcctccga ggccgcgcgg gcgatcgtgg
     1621 agttcgcgct ggacgcgccg gaggtgcaca ccgtgcgggc ggatgtggaa ctgggcaatc
     1681 cggcgtcgat acgggtgctg gagaaggccg ggctgcggcg ccgggtccag gacgccacga
     1741 cggcgcggta ccagatcacg gcgcaggagt tcgcacggct gtctgccgga ccctcctgac
     1801 ccgccgcagc agggcgccgc tcgccgcgcc gagggtcagt gacagcaggt gaccccagtc
     1861 cgagaccggg tcgaggtagg cgagcagatc gctgacggcc agggcgccgg ccgcgaacag
     1921 cagcggcagg cgcccccacg gcgggaggag gacggccagc gccccgacgc aggtcatgac
     1981 gccgaagctg atgccgtaat cgaggcggtg cagggccgag ccgggcagtt gccccagggc
     2041 gaccgacagc ccgaccggca cttccgtcgc gagggtggcg atggcgtggc cgccgaagaa
     2101 gacggcggcg gtccgcaggg agccgacccg ccgctccagg gcggtcagca cgaaggggaa
     2161 ggcgagggcg tacgccgaga gcagcccgcc cgcgctccac agggcgctgg tcaggagcgc
     2221 cagcagcggt gcgtgcgcga ggtgctggac gtccgtactg gagccgcgca gcaggtccag
     2281 tacgagcgcg gggtcggcgt tctcggcgaa cacggtggtc gcggcgagga ggagggcgta
     2341 gcagaaggtg aagggggcgc cggtgggcgt gggcagcagc cttccgggcc gccacggcgc
     2401 gaggccggag gcgggcgcga ggccgggatc gtgcacgagg ccggaggccg acacgaagcc
     2461 ggaatcgggc acgaggccgg agaccgacgc gaggccggga tcgggcggag aagcgtgttc
     2521 gggcggggaa gcctgcccgg gcgcagaaac ctgctcgatc ggggaagcgt gctcgggggc
     2581 ggggatgccc gcgagcaggg ggcgatcgtt cttcccggcg gcgtccgcct cggtggcggc
     2641 catggccgct gatccctccc ggctcactgc ttcccggctc cttcggtcga tcgtcacgtc
     2701 ggcggcgcgc acggcgggcc gcgcccgcac cccctcggcc acggctcccg gcagcgggcg
     2761 aggcggaaca cgccactccc aagacgacaa cgttcgcacc aatctccacg ttcaacccat
     2821 gaatcggccg ttccagtgac atgcgtcact tggggcaacc gcggtggtgc gagtggcatc
     2881 aggggagcgc gcggggaacg gccgcccgcc ttccccggct ggacggccgt tccggtggtt
     2941 cgccaagatg gcccgcatgg ctcccgtacc ttccgtatac ccaccccagg tacatccccg
     3001 tccggatcag gccggtcaag agaacgagca ggacgcgccg gacgcgccgg acgcgtacga
     3061 cgggccgcgc gtgctggacc ggcgcgaggg cccgtacggc gaagtggtgc tgcggcagcg
     3121 gggcgagcac ttcgagatca tcgccaacgg ctgtttcctc atggacacct ccgacggccg
     3181 gtccgagcgg ctgctgatcg acgcggcgct ggccgcgctg cccgccggac gcgagcgccc
     3241 cgcgctgctg atcggcggcc tgggggtcgg tttctcggcg gtacgggccg cggccgagcc
     3301 gcgctggggc cggatcgtgg tggtcgagcg ggaggacgcc gtcgtggact ggcaccggac
     3361 cggcccgctc gccacgctct ccgcgcccgc gctggccgat ccccgtaccg agatcgcgcc
     3421 cgcggacctc ctgacctacc tccgcgagga caccggcccg gacgccttcg acgcgctgtg
     3481 cctggacatc gacaacggcc cggactggac ggtcaccgag gacaacggcg gcctgtactc
     3541 ccccgcgggt ctggccctgt gccgggaccg gctcacgccc ggcggggtgc tcgccatctg
     3601 gtccgcgcag ccgtcgtcgg atttcgaaac atccttgcga aatgccgggt tcaccggcgt
     3661 acgtaccgaa gaagtgccgg ttgcccgagg cgtccccgac gtggtgcacc tcgcccacaa
     3721 gggcgcgtag ccgccggtca caccctgcct ttacgctgct gcccagcagg agcgacgagc
     3781 aacacgcgac gagcagtacg cgatgagcag cacgcgacca gacgagccgg acgagcggta
     3841 cgcgaccagc ggtacgcagc cggcacacgg ggacacgcag gggcgggcga tggatcagac
     3901 gcagaccacc cagggcggca ccgccgcggc cacgcccggc gcccagcgcc ggatcctcgt
     3961 cgtggaggac gacccgacga tcgtggacgc catcgcgacc cggctgcgcg ccgaggggtt
     4021 ccaggtgcag acggccaccg acgggccggc ggccgtggac accgccgagg catggcagcc
     4081 ggacctgctg gtgctcgatg tgatgctgcc gggcttcgac ggcctggagg tgtgccgccg
     4141 ggtccaggcc cggcgcccgg tgccggtgat gatgctgacc gcgcgggacg acgagacgga
     4201 catgctggtc ggcctggggg tgggcgcgga cgactacatg accaagccgt tctccatgcg
     4261 ggagctggcg gcgcgggtgc atgtgctgct gcggcgggtg gagcgcgcgg cgctggccgc
     4321 ccatacgccg cgcagcggca tcctgcgcct gggcgagctg gagatcgacc acgcgcagcg
     4381 ccgggtgcgg gtgcgcgggg aggacgtcca tctgacgccc accgagttcg acctgctggt
     4441 gtgtctggcc aacaccccgc gcgcggtgct ctcccgtgag cagttgctgg cggaggtgtg
     4501 ggactgggcg gatgcctcgg ggacccgtac ggtcgacagc cacatcaagg cgctgcgccg
     4561 caagatcggc gccgagcgca tccgtacggt gcacggcgtc ggttacgcgc tggagacccc
     4621 gcccgcatga cctcccgtac gacccgccgt acggcccggg aaggggcggc ccggggcgcg
     4681 gcccgcagcg gggcgtccgc gcgcaggtgg tgggagcggg tctgggagcg cgtatgggaa
     4741 gggctgcgcc ccctggatcc gtaccgctcc gtgaaggcgg ccctgggcgc gctggtcatc
     4801 gtctcggtga tcatcaccac tctgctgatc ttcgtcgcca tccattcggc gaccgagctg
     4861 cgcatcatca ccgtgttctc cgtcatcgcc tcgctgctgg tcacgcagtt cgtcgcgcag
     4921 agcctgacgg cgccgctgga cgagatgacg gatgtgacgc ggtccatggc caacggtgat
     4981 tacacccggc gggtgcgggc cgaacggcgg gacgagttcg gtgatctggc cgacgctttc
     5041 aaccgcatgg ccgccgatct ggaggcggtg gacactcacc gtaaggagct ggtcgccaac
     5101 gtctcgcacg agctgcgtac cccgatcgcc gcgctgcgcg ccgtactgga gaacgtcgtg
     5161 gacggcgtct gccggcccga tccggagacg atgcgtacgg cgctgaagca gacggagcgg
     5221 ctgggccggc tggtggagca ccttttggac ctctcccgtc tggacaacgg ggtggtgccg
     5281 ctgcacgccc gccgcttcga ggtctggccg tatctgtcgg gggtgctcaa agaggccaac
     5341 atgagccgtg gcgcggccac cctcgccggc tcggggacgc acacccgtac ggacgtccac
     5401 ctccacctcg acgtatcgcc gcccgaactg acggcgtacg cggacgccga gcggctccac
     5461 caggtcgtgg ccaatctgat cgacaacgcc atcaagcaca gcccccggca cggccgggtc
     5521 acggtgcggg cgcggcgcgg cgcggggccc gagagcctgg aactggaggt gcaggacgag
     5581 gggccggggg tgcccgagtc cgagcgccac cgcgttttcg agcgcttcaa ccggggtggt
     5641 ccggggccct cggggccggg tacggacggc ggtacgggcc tggggctggc gatcgcccgc
     5701 tgggcggtgg atctgcacgg cggacgtata ggggtggccg aatcccccgt ggctgccgca
     5761 tccgcgtcac ccttccgggg atcgactccg cgcgaagctg acgatcgttg acgtagggtc
     5821 gttggtggag acactcatcc agtcggtgcc tcggcgatga gccgtacccg caagcaggca
     5881 aaccaggtgt gtttcccgcc aagtcatgcc cgcaaacccg tagctgaatg tgacgtacgc
     5941 gacgactgac cctcccggac tgcaccacgg cttccgagag gcgtagcctt tattcccgct
     6001 gtccaccacc tttaggaagc ggaagagggc ggttgccgcc gtgtcgccac agtcccccaa
     6061 cagctcgagc aactcgaccg accaagaggg gcagggaaag aaccctgctg ccgcgttcgg
     6121 tccaaatgag tggctcgtcg acgagatcta ccagcagtac ctccaggacc cgaactcggt
     6181 agaccgagcc tggtgggact tcttcgccga ctacaagccg ggagcgggcg ccaccgcccc
     6241 gtcctcggcc agtgaaggca gccccgccac tcaggccacc ggaacggccc cggccgcacc
     6301 gggtgccgcc gcgccgagcg cgcccgcggc ccccgccgcg cagcagcccg cgccgccggc
     6361 cgccgaaccc gccgccgcac ggcccgccgc cccggcccgg cccgccgcga gcgccccggc
     6421 gcccgcccag gccgccccgg cccaggccgc tcccgccaag accgcacccg tgaagaccgc
     6481 tcagcccgca gccaagaagg acgacgtgaa ggccgacgag gcacccgcag gcccggaact
     6541 ggtcactctc cgtggcccct ccgcagccgt cgcgaagaac atgaacgcct ccctggagct
     6601 gcccacggcc acgtccgtgc gcgcggtccc ggtcaagctg ctcttcgaca accgcatcgt
     6661 catcaacaac cacctcaagc gcgcccgggg cgggaaggtc tccttcaccc acctcatcgg
     6721 gtacgcgatg gtgcaggccc tcaaggccat gccgtcgatg aactactcct tcacggagaa
     6781 ggacggcaag ccgacgctgg tcaagcccga gcacgtcaac ctcggcctgg ccatcgacct
     6841 ggtcaagccc aacggggacc gccagctcgt cgtcgccgcc atcaagaagg ccgagacgct
     6901 cagcttcttc gagttctggc aggcgtacga ggacatcgtc cgccgggccc gcaacaacaa
     6961 gctgacgatg gaggacttca ccggagtcac cgcgtcgctg accaacccgg gcggcatcgg
     7021 caccgtccac tccgtccccc gcctgatgcc cggccagggc ctcatcatcg gcgtcggcgc
     7081 gatggactac ccggcggagt tccagggcac ctcccaggac accctgaaca agctgggcat
     7141 ctccaaggtc atgacgctga ccagcacgta cgaccaccgc gtgatccagg gcgccgcctc
     7201 cggcgagttc ctgcgcatca tgaaccagtt gctgctcggc gagaacgact tcttcgacga
     7261 catcttcaag tcgctgcgca tcccctatga gccggtgcgc tggctgcgcg acatcgacgt
     7321 cagccacgac gacgacgtca ccaaggcggc ccgggtcttc gacctgatcc acgcctaccg
     7381 ggtgcgcggc cacgtcatgg ccgacaccga cccgctggag tacgagcagc gcaagcaccc
     7441 cgacctcgac atcatcgagc acgggctgac gctgtgggac ctggagcggg agttcgcggt
     7501 cggcggcttc gccggcaagt cgatgatgaa gctgcgcgac atcctgggag tgctgcgcga
     7561 ctcgtactgc cgcaccaccg gcatcgagtt catgcacatc caggacccca agcagcgcaa
     7621 gtggatccag gaccgggtcg agcgcgggca ctccaagccc gagcgcgagg agcagctccg
     7681 catcctgcgc cgtctgaact ccgccgaggc gttcgagacg ttcctgcaga ccaagtacgt
     7741 cggccagaag cgcttctcgc tggagggcgg cgagtccgtc atcccgctgc tggacgcggt
     7801 catcgactcc gcggccgagg cgcgcctgga cgaggtcgtc atcggcatgg cccaccgcgg
     7861 ccggctgaac gtgctcgcca acatcgtcgg caagtcctac gcgcagatct tccgggagtt
     7921 cgagggcaac ctcgacccga agtcgatgca cggctccggc gacgtgaagt accacctcgg
     7981 cgccgagggc accttcaccg gcctggacgg cgagcagatc aaggtctcgc tcaccgccaa
     8041 cccctcccac ctggaggcgg tcgacccggt cgtggagggt gtggcgcgcg ccaagcagga
     8101 catcatcggc aagggcggca cggacttcac cgtcctgccc gtccagctcc acggtgacgc
     8161 ggccttcgcc ggccagggtg tggtcgccga gacgctgaac atgtcccagc tccgcggcta
     8221 ccgcaccggc ggcaccgtgc acatcgtcat caacaaccag gtcggcttca ccgccgcgcc
     8281 ggagtcggcc cgctcctcca tgtacgccac cgacgtggcc cgcatgatcg aggcgccgat
     8341 cttccacgtc aacggtgacg acccggaggc cgtggtccgc gtggcccgcc tggccttcga
     8401 gttccgtcag gcgttcaaca aggacgtcgt gatcgacctg atctgctacc ggcgccgcgg
     8461 ccacaacgag tccgacaacc cgggcttcac ccagccgctg atgtacgacc tgatcgacaa
     8521 gaagcgctcg gtgcgcaagc tctacaccga gtccctcatc ggccggggcg acatcaccct
     8581 ggaggaggcc gagcaggcgc tccaggactt ccagggccaa ctggagaagg tcttcaccga
     8641 ggtccgcgag gccaccacgg ccccggccgc gcccgaggtc ccgcagccgc aggccgagtt
     8701 cccggtccac gtggacaccg cggtctccca ggaggtcatc aagcggatcg ccgagtccca
     8761 ggtcaacatc cccgagcggg tcaccgtcca cccgcgcctg ctgccgcagc tccagcgccg
     8821 cgcggcccag gtcgaggacg gcacgatcga ctggggcatg ggcgagaccc tggccatcgg
     8881 ttcgctgctg atggagggca ccccggtccg gctcgccggc caggactccc gccgcggtac
     8941 gttcggccag cgccacgcgg tgctggtgga ccggcggacc ggcgaggact acaccccgct
     9001 gctctacctg tccgaggacc aggcccgctt caacgtctac gactcgctgc tgagcgagta
     9061 cgcggcgatg ggcttcgagt acggctactc cctggcccgg ccggaagcgc tggtcatgtg
     9121 ggaggcgcag ttcggtgact tcgtcaacgg cgcgcagacg atcgtggacg agttcatctc
     9181 ctcggccgag cagaagtggg gccagacctc cggcgtcacg ctgctgctgc cgcacggcta
     9241 cgagggccag ggcccggacc actcctcggc ccgcatcgag cgcttcctcc agctctgcgc
     9301 gcagaacaac atgacggtcg cgatgccgac gctcccgtcg aactacttcc acctgctgcg
     9361 ctggcaggtc cacaacccgc accacaagcc gctggtcgtc ttcaccccga agtcgatgct
     9421 gcgtctgaag gcggcggcgt ccaagacgga agagttcacc acgggcggct tccgtcccgt
     9481 catcggcgac ggcacggtcg acgccaccgc cgtccgcaag gtcatcttct gctccggcaa
     9541 ggtctactac gacctggagg cggagcgggc caagcgcggc gcgaacgaca cggcgatcat
     9601 ccgtatcgag cggctgtacc cgctgccggg ccgggagctc caggcggaga tcgccaagtt
     9661 ccccaacgcc gggaagtacc tgtgggtcca ggaggagccg gccaaccagg gtgcctggcc
     9721 gttcctcggc ctgaacctga tcgaccacct ggacctggcg gtcggtgccg acatcccgca
     9781 cggcgagcgc ctgcgccgca tctcccggcc gcactcctcg tccccggccg tcggctccgc
     9841 caagcgccac caggccgagc aggcgcagct cgtcgcggaa gccttcgacg cctgatccgg
     9901 cgccgtgggc ccgtcccgcg tcacctgtga cacgggcgag cgaacacatg gaagggcccg
     9961 ccccgcatcg cgcggggcgg gcccttcgcc gtacgtccgc tcacctcccg acgtccgggc
    10021 ccggcccgtc gtcgtagtac gccaccgggg cggcgtcgcc gtgggcgcgc tcctccagta
    10081 cggccaccac ctcggtgagc accggatgcc cgacccgctg ccgcaggccg gccaggtccg
    10141 ggcgcccgaa gtcgggcagc gcttcctcgc ggggtgccgc gtcccggcgc gcctcggtca
    10201 ccggcgcgcc gccggtcccg gagtccgaca cggttctcct cctccttccg ggagccctcc
    10261 ccgccgcctc tacacgggct gtggttcgaa gtcccagtac gggcgcctgc ggcgccgggc
    10321 ggacagggtg tgggggtgtt cggggcccag cgtctcggtg agctgctgga cggcttcctg
    10381 ctccagcttc gccgcctcct gcccgcgccg cagcgcgcgc aggtcctcgg ccagtccggt
    10441 cttggccgac agggtcagcg gatgggtctc ccccaggacg gtcttggccc gctccatggt
    10501 gtcccggctc agctcgacgg cgccctcctc gtcatccgcc cggttgcgcg ccccgctggc
    10561 gttcagcgca cagcccagcg tccagggatg gtccgggccc accgcccgcc gcatcccgct
    10621 cagcgcccgc tcggcgatgt ccagcgcctc ggacacctcg ccgaactccc cgcgtaccag
    10681 accggtgttg cccaaggtac ccacggtgta cggatggtcc tcgccggcca gcgtccggta
    10741 gcgctcggcc acttcctcgg ccagctcgcg ggcgtgcccg aggtcgccgt gctcacgcag
    10801 gaacgtggcg tagtccgccc gcaccatcag cgtctccgga tgccgcggcc cctgcacccg
    10861 ctgggagcgc tccatgacgt cggccatcag ggagtccgcg tgggacaggt cgcccgcgcg
    10921 gcgcaggcac agcgccaggt tgtggtcggc gcgcagtgtc tgcgggttgt gcgggcccat
    10981 cacctggtgg tgcaggcggg cgttgaggtc ctggcgggag gcggcgtcgc ggtagtgccc
    11041 gagcaggcgc agcatccggg cgtaggacgt gccggcgttg agggtgaggt ggtggcgggc
    11101 acgcagttcc cgctccctga tggccagtac ctcacggtag gtgaccagcg cctcttcgta
    11161 ccggccgagc atgcccagcg ccgcgccgcg gttgacccgg caggagagcg tacgcggcgc
    11221 ctcggcgccc agcagctcga cgtacgcccg ccagaccgtg tcgaagagcg cgaacgcctc
    11281 ctcgtacgag cccagggcca tcagcgtgcc cgccaggccg tcctgggccc gcagcaggtc
    11341 ggcgtcgatc gcctcccgct cggccgagag ctggtccacg atcgcgctgc cgaccgcctc
    11401 cgcctcgcgg taacgcccca gccagcgcag catgttggcg tgctggtggg tgaggatgag
    11461 catggtgcgc tgagtcggcc tgatacgcgt acgccatcgg gagaggaact gctcgcacag
    11521 tttcagtccg atgcggtact cacctcggac ccgcaggtac tcgatgcagt tcagcagcat
    11581 ctcctggacg gactgctcgg ggctgtccag gacaccggcc ggctccaggt gcgggatcag
    11641 ctcggcgtag cgctcccagt agcgggtgtc ggaggggacc tgcggatcgg cggagaccag
    11701 cacccggcag gccgtcgccg acatccggtc ccgctcgtcc tcggacatgt cgctgcgcag
    11761 gaagcggtgg tagagccggt gcatctgcgc cgtctccacc gccgggtcga aggtctgcga
    11821 cacctggtag tccagccgta cggcggtgga ctcggtcagc cggcgcagcg cggtgttcca
    11881 actgatcggc tcggccgcca agtcggccag gtgttcggga aggtcgccgc ggcgggcctt
    11941 ggcgagcatc ggtacgggaa tggcctcggg cgcgaagaac gcaaacagct tcagcagctc
    12001 caccgccgcg ggactgcgct cccgcagcgt gttgagcgtt atggcccagc tcgtctggaa
    12061 ggccatcgga tagtcggagg agatccggat gccgaccagg ctcggttcgc cccggcggat
    12121 cagctcgatg tactccttgg gcgacatggg gttggcgtcc agccaggccg cggtctgcgc
    12181 cagcagcagc ggcaggtcct gtacggcctc ggcgagcagg tccgcctcca tgggcgtcag
    12241 tcgcggggcg cgccgccgcg cgtaggcgac gctctccgta cgggtgaagg gcagcacctc
    12301 gatctcctgg gcgctgccgg agccggacca gtcgcgggtc agcgtggtga tcaggacgtg
    12361 gccgcggccg tcgggcacca ggtcctcgat ctgctccatg tcgtccgcgc tgtcgaacac
    12421 cagcagccag cggcggtacg ggcggccgat ccgcagcgcc tcgtggacgg cccggatacg
    12481 gtcgcccagc tcctggccga ccggcaggtt cagccgggtg gccagctcgg cgagctgctc
    12541 ccgggcagcc ccccggttgg tggcgctgat ccaccacacc acgtcgtagt cgttgccgaa
    12601 ccggtgcgcg tactcggccg cgatctggct cttgccgaca cccgagatgc cgtacagggc
    12661 gatacgggtc tccagcggcg ggcccgagcc cagcccgccg gccagcttcc cgtgcagatc
    12721 ctccagcacg ttgtcgcggc cggtgaaacg gttgttgcgg cgtgggatgt tccacacctc
    12781 gggagggtcg ttggggaagc gcggggcgtt ggtgaccgcg tcctccgcgc gccgccggcc
    12841 cgggtcgacg cccaggcggt gcaggacgcg gcggttggcc tcgaccgcgt ccaggtcgcg
    12901 caggtcggcg gggcgcagga tggaagcggt gctcggcagc cgctgggtgg ccacgctcac
    12961 cgccgcgaaa cgctcgacgt gcggcgccac gacctcctgg agggcggccg tccactcctc
    13021 gtgggtcttg gggcccagcc ggaagtacca gtcgtccagg accatcagga ggcggccctc
    13081 ggcggccagc aggccggcca gttcctcggt gagcgggctg ttcgcggacg ggtcccagcg
    13141 cagcatggtg gtgccgtgcc ccagttgctc caactggtgg gagatccacg cggcccatgg
    13201 ccggttgaag cccgcgtagc tgatcgtgat gtgctcgttg gagccggtgg tggtgggctg
    13261 atcgaccatg cgaccgtctc cctgggatgc ggtggtccaa gcgtgcgtga gctggctgct
    13321 cggcacgata gcccaagtgt ccccccatat ggcgacagtg cgtcaggtca tgttgcgtgc
    13381 cgggtagttg aacacgccga ccgccggtgc agccggccgg gcgggcgcgc cggtcagcgg
    13441 ggtgcgccgg cgaccgccgc gctgaggcgg ccggcgatgt gccggatcag cctttcgaga
    13501 tcggcgcagt acacggacgg attacggaaa ccgctgccgt cggcccggta gcggtgcgcg
    13561 tagttgccgc cgccgcagac ctccatcagc gcgcagccgc ggcactgcgc gcccaggctg
    13621 agcgccccct gctggcgggc ggccatgccg gggtggtcca gcgcctcgtc gaaggtgttg
    13681 cggaagacgt ccaggccggt cgcggcggct ccgtcgtacg tggacttcag ggagtccacc
    13741 tgttcgatgg cgccgtcggt gtccacgacg agggcgacga cgggcgagag gccgaccgct
    13801 tcgctgctgc tcggccggcc cagcagcagg ccgatgatct ccgtgaagcc gcggacccgg
    13861 ggggcgccgg ggggctcctc ccaccacagg tcgaagacgg tgcacagcca gtccccgtac
    13921 ggagtggggc cgggggcgcc cgggggtgcc gggggcgggc tggaccagtt ggcgtgcggg
    13981 aggaggaagt cgagcatcgg ggggttcagg gcccgcagcg agtggtagac ctcggccggg
    14041 tcggaggtga tgtcgatggt gcacaggacg cccgcgaaga cttcggggcg ccgggcgagc
    14101 agccgcgcgg cgcgggagac atcgggccag gaggggcgcc cggcgtggtc gacccggcgg
    14161 cggttgagta cgggcgtgcc gccgtccagg ctcagaccga cccggaatcc cgcgtcggcc
    14221 agggtgtcca gcacggggtc cgtcaggagg gtgccgttgg tctgcacgcc gaaggcggcg
    14281 gcgcacccct cggggagtac ggcgcggacc gccgccgcct gctccaggag cgggcccggg
    14341 ccggtgagca ggggctcgcc cccgtgcagg tcgacgcgga tgccggcgag ccggtgggcg
    14401 cggacgtgct cagcgatgcg cagggcggtc cgccgcatcg tggcgggggc cacccggcgc
    14461 ggccggtcgc gccaactggc gtccgggctc tggtagatgt agcagtaggt acaggccagg
    14521 ttgcaccggc tgtgcacctt caggacgaac tgccggaagg gcacccggat cgtccggtcg
    14581 gtctcgcact ccacggcgcc gctccctgct tccgtcgacg accggaccgc acgtcaccgt
    14641 acgtttgtcc gctgttgtga tgcatggctc gggcatcgaa caggaaaccg gagtacgcgg
    14701 gcaactggcc ggtttgggcg cgcgattgcc caaaaagcgc cgccgggagc gggccggaac
    14761 ttgagcgcgt caagccgtca gggcgggctt caggacttca cggcctcagg gttcacgacg
    14821 tcagggcttc gtgacgtcag gacttcacga cctcaggact tcacgacgtc acgacttcat
    14881 gacgtcacag ggagctttcc gggatcgaag acctcacccg ggtcccccgg cccgtcctcg
    14941 tagtaggcca ccgcctcgtc cgccgcaggc cagttgctca gcagcagtgc cgccaccgct
    15001 cccagcaccg ggtggccgct gtgctcggcc accgaggcca catcgacgcc gccgaagtcg
    15061 gggagcggct cggccgacgg gccgggcggc ctgaccgggg ccggaccggt gagcgcaatt
    15121 gtcaccacac tgctctcctt cgggctggtg gacaggggtg ttcccgaacg cccgtgcacg
    15181 gaaacacctt cccggtcagc cgtcaatcgg tggccaccag agcgcgcatc cggtcccggg
    15241 tgcgccgggc ctccgggccg ttctcctcgg aggcccgctg ccactgcgcc cagctctcct
    15301 cgtacgcctg gagggccgac tgcttgcccg ccgtgtcctc cagcacctcg ccgcgacggt
    15361 ggtgggcgcg cgccgccagc agcgggttgt ccgcccgctg ggcgtcggtg gcggcccggc
    15421 ggtagcaggc cgcggcgcgg tcgtggcgct ccatggagtc gaagcggcgg tccagcagga
    15481 gctgtacgtc gccgacttcg agccaggctt cggcggagac ggccgggtcg tccgagccgc
    15541 gcgccgccag ctccaatatc cagtcggctt cgtgcaggtc ggccagggag ggctggcgtt
    15601 cgtagcgcag ccgcagggcg cggccgaaca gcaggcggtg ggcgcccagg ccggggtcct
    15661 gcggggcgac ccgggccagc gcctcccgca ggacgtgtac ggcctcgttg gccatccgct
    15721 tgccgggctc ggcggcgggc tccaggcggg cgcgggtgag cagggccgcg ccgcgctcgg
    15781 cgagcaggga gctgtgttcg ggggtgtcgg gtgtggtcag gcgcagtgcg gcggccagcg
    15841 cgtcgatggc ggcgtccagg gcggtcaggt cgccggtacg ggcgtggacc gtacggtggg
    15901 cggctgcggt acgggccagg ctgtcggcct ccagggccgg gtcccgcagc tcgtgggcca
    15961 gggcgcgggc gcgctccagg gtccgcagca ccgtgggcag cgcctggtcg tcgaagacga
    16021 ggagcgtacg ggcctcggcc agttccagga gcgactcgca gatcatccgg tcggccgtgg
    16081 cgccgcggcg gcgcagcagg acggtggcgg tgtccaggtc ggcggtggcg cgcagcgcga
    16141 gcgggccggt ccggcggccg tcgtccgtgg tgtcccgggc ggcgcggcgg gcctggtcca
    16201 ggaagacccc gccgcgggcg gcgtagatct cgccgggcac ctgctccccg ctgggccacc
    16261 gttccagcag ggtcgtcagg gccccttccg cctccttcag ggggtcgtgc gcggcgcggg
    16321 gcggccaggc gacgccggag gggggcgggt cgggggccag tgccgccagc cggcgcagca
    16381 cctccgtacg cagcaccatg cactccagta cgcggtcgtc cagcaggctc atcagcccgc
    16441 acgcgctctc caggtggagg gcggcgtcct ccagggcggc gcgttcgccg gagacggcgg
    16501 aggcggcccg gcgttcctgc gcgccggcgt accgtacgcg ggcgagcacg atcagcgccc
    16561 gcagccgggc ctcgccgtcc tcgtcgtgtc cggacccgac accggcggcg gcctcctctg
    16621 cggcccgtac cgcccgctcg gcctcctcca gggcgtccgg ctggcgcaac tgcgcccagg
    16681 cgtgcagcag ggcgcgggcc aggtccgtgc cggcctcggg cagccgctgg gcggcggcgc
    16741 gcagcagccg tacggcctcc accaggtcgc ggacggcgcc gtcctgttcg tagcgctcca
    16801 ggtacgcggc gccttgggcc gcgggtccgt cggtggcgta cacctgcggc acgggaggtt
    16861 tgatggccgg ctcgaagcgg cgcagcacgc gctccgatat ccgggcgaac ggctcgggca
    16921 ccgcgcgccg tccggtctcc ggctcccggc cgctgccgca gagcatggcg acggccacgg
    16981 cggggaagtt gcgggcgctg cgcccgaagg tgcgctcgat gtacagggag cagtgcttga
    17041 ggaccagggc ggcctcgccg gcgctcaggc ggcccagcag ttcgtcccgt acgccgggta
    17101 cgaagtcgta ccaggggccg gccgcctcgg cttcggggcc ggccgggcgc tcgggcgcgg
    17161 gaagctggac gaccagcccg ctgagcagca cttcggccag ctcggcgggt ccggtctgcg
    17221 gcagcatggc gcgctggacg agctggatga cgggcagcgc cagggggacc gccgagaggt
    17281 ggacggccag gtggcgggcg gccggggagg cggtgcggtc gaactcgccg atcagctcca
    17341 ggggatcggc ggtcccgggc tgcggcgggg gtacggcgcc caggccgtgg tccgcccgta
    17401 cggtgcaggc ggcgccgcgt aaggacagcc cggactcggc ggcggccagc cgcgcccacg
    17461 tgccgagggc ggcgggggca gcggagagga ccggtacgac gcgctcgcgg gccgggcggt
    17521 agccctcgcc cggcgctccg gcggccctgc ggcggcggcg cgcgggctcg aaccccaggt
    17581 ctccgtaagg gccctggtgc cggatgagcg tcccggggac ggcgggcagg aacgtacggg
    17641 cccacatgcg ctgcgggagc ggctggacga cggcgaccgg cgcgtcggcc acccagcggt
    17701 acagcagccg ctgcatccgc ccgtcctccc acagaggtcc ggcgcagtcg ctgacgacga
    17761 gggtgaggtg gtggccggtg gggtcgtgca gttggtcggc cgggcgcagc gggtcgccgg
    17821 gggcgggccc ggcggcgacg ccgacgtcct tgccgtacgg gtggaggtag tgcaccgtca
    17881 cgtcgcggaa ggcaccgacc cgctcgcaga cctgccgcag gtcgtgcacc atctgctccc
    17941 atatggccat ggaggcggag ccgtccatga acaggcgcag cgcggcctcg cggcggtgga
    18001 tgccgcggaa gacggggatg agcatttcgg cgtgggcgga gagttcggcg gtgccggtct
    18061 cgtccagctc ctggcgggcc ggggcgacgg gcgggcggta gcgctggacg ggccgcaggg
    18121 cgcgctggag cggcagcagg ccggggaagg cggaggcgac cgggacgccg acctcgccga
    18181 ggccgtggcg gtcggggtcc gggccgtggt cgccctggga gggcagcagg tccacgtcgc
    18241 gccgggtggg gcgcgaagcg gattccgtga gccgtgggct gtcgcgggcg ggctcccgcc
    18301 gctgtccgcc gacggagaat gtggccggtt ttctacggtc ctggccgttc acgtcgtccc
    18361 ggtcgtcggg gggtgcgggc tccggctgtc cgccgggcgt gatccattgc gcgagccaca
    18421 gcgcgtccgc catcgcgcgg gcgtccgcgg gcagccccgc cgcgcgcagc cgcgcgacga
    18481 gctggtcgag ggggccgtgg cccggctcgc cggcaggcac ggcttcacct cgtccgatcc
    18541 agaggacgca tcagctccgc cgtcaggcgc cgccgggtct cctcctcgtc ctcgtccgtc
    18601 cagccggctt tctgggtcag gtggatggcg ttgaagagct ggtccacggc gcgtacgtca
    18661 ccgggctcgc ggtccaggaa ccggtcgatg accgactcgt accgctcggc ggcgtcctcg
    18721 ccgaagtgtg cccgcaccat gcccgccagg cgctccttgt tgggcgtggg gatgttcagg
    18781 tggatgcagc ggcgcagcag cggggcgggg aagtcccgct cgccgttgct ggtcaggacg
    18841 atgaacggga aggcgcggca gcgcacccgg ccgttgcgga cgcgcacgcg tgtgccgtcg
    18901 tcgctgagca ccgggacctc gggggcggag gcggacagcc gctccagctc cgggatcgtg
    18961 aactcccctt cctccaggac gttcaggagg tcgttgggca ggtcgatgtc gctcttgtcc
    19021 agctcgtcga ccagcagcac gcggggtttg gcggcgggca gcagggccgt gccgagcggt
    19081 ccgaggcgga tgtagcggcc gatgccgccg ccgggctcct cctcgggcgc ctcacccggt
    19141 aaggcgtcgg gggccgcggc gtcggggccc aggggcggcc tgggcggcac cgcacgggct
    19201 atctggaggt cctggaggcg gccgatggcg tcgtactggt acaggccgtc gcggagcgtg
    19261 ctgcggctga cgatcggcca gttcaggacg cggcccaggc ccagctcgta ggcgacggag
    19321 tgcgccaggg tgctcttgcc gctgcccggg gcgccggtga ccagcagggg gcggcgcagg
    19381 tacagcgcgg cgttgaccag ctcgcgctcg gtctcgccgg gccggtggta gctggcctcg
    19441 cggctcagca cgcccagacg gcgctcggat gcgtggtcga gtgcggccgg cggcgccacc
    19501 agcggctcac cgtcgaaatc ccgccagggc ggcggcggtg ggagctgttc gatgccgtcg
    19561 tgcggagccc ccgcgccacg atagatgagc cagtcgctca cgtcggaact cctcgtcgcc
    19621 ggccagccgt cgggcaggaa cgggcggtcg tggaggaccg tccgggaagc gacagcgtcc
    19681 actcccgagc gttcccccgc gcccgccaca agctatctct cacgaacaca agcaatctct
    19741 cacgaagcta tgacagtacc cagccgtacg gaagcgcgtg gggcggtttc cggtctcatg
    19801 agatttcacc gggaggacaa ttggggccca ccggcgaaga gttgagggat gggattgtcc
    19861 gggtcgtcgt acagcaggac caggtcgcgt gcccagtggg cggacgtttc ctcggctctc
    19921 ccgcgcagct ccctgaccag ttcgggcagg gcggtcaccc ccttcgcggc gagcaggtcc
    19981 cgtacctcgc ggtggaagtc gtcacaggcg ctgtcgcact cccgttcgtc gtgtccctcg
    20041 gagagccaca ggcttaccgg gtacccggcg tccagggccg cgccgaccgc gtccagcccg
    20101 gtcccgacgg cgaccgaacg gcagagtgtg gggaccgctc cctcctcgcc gttctccagc
    20161 agccgccaga cgctttccgg cccgccgccc gcgcgcggcg ggacacgcag cgcggacagc
    20221 tccggggcgc ccatgaggcc gcgccagcgc cgcagccagg ccgggtccac cgcctggcgg
    20281 cggccctggt cgcgcaggac caccgggcgc ccggagccga tcgggcgggc ccgggcgccc
    20341 gcccgcgtgg agaccggcac cgcccagcgg tccgccggga gctgccagta gccctcgggt
    20401 acggcgacct ccaggcgcac ccggccgccg gggcccacgt cgccgtcggc ccgcagcagc
    20461 cgggggccca gccgccgcag gacctgcgcc tgggcctgct cgaaggtcat tccgccctcc
    20521 gactcctgga ggtcgacgcg catccactcc ccccggccgt acccctcgct gaccgaccag
    20581 ttgaagagct gctgcccgcc gtcgccgtag aacagcggtt cgaactccac cagcaccgcg
    20641 tccggccggc gcggcaccgg gccgatccgc cggcggtcct tgggcagcag cacggccgcc
    20701 ttgtccgtca cgaaccgcgc gagccgctcg gcggcctccc gcacccgcgc ggcctcctcc
    20761 ccgggcaccc cgcgcacttc ctcggacgtc cgctgggcca cgatccgcag gtagtgcacg
    20821 aaggcgcagc gctccgaata cgggtcactg ccctggtaga gcacaccgtg gccgtcccgc
    20881 cacgtacgca gcgaccaggt cccggcccgg tcccggccgc ccagcacctc gcacaccgcg
    20941 gcctccacga ccagcgggtc gcgcggggcg ggcagccgcg ccagcaggtc cagcgcctgg
    21001 aggcgctcgg ccacgcccca cagccgctcg cggccggcca tgatcgcgta ctgggcgtcg
    21061 aaccaggtgg gctcgccgcg ccggccgagg tcctggcccg cccagtgcca gcggtcgtgc
    21121 agactcatca gttcgtggta cgggtctggg cccaggcccg tacggcccgg taagaggtgc
    21181 tgggggccca gcgcgcgcag cgcggtgacc ggcaccgcca ggcccacctt gtcctcctgg
    21241 tggcggccct tgacgatgcc gaccacctca cctcggtcac agtccagcag agggcccccg
    21301 gacgcgccgg gcgtgacccg tacgtcgctg ccgaactgga ggccccgggc gtcccgggcg
    21361 ccgaagcgga cggcgatgaa ggggtccacg ggcgcctgcc ggacaccggc ctcgatcggg
    21421 gcgcggcccg gaccgtgcgc ccctccgggc acgtacacgc cccctcggcc gtacgcaccg
    21481 ccctggccgt acgcccctcc gctgtcatat gcgccggcgg agtcgtacgc atcaccgggg
    21541 tcgtatgcac caccagggtc gtgcgcgtca ccggagtcgc gcgcatcacc gggcgcaccc
    21601 gcgtgtccgc acgcgcccca cgccccggac ccgccgagct ggtcgtgccc gcggaagatg
    21661 tacgcgtcct ccagcagggc cgcgtgctga tcgctgagcc aggcgcaccg gtgctccggg
    21721 tagggctcca gcagccggac cagagccagg tcgggccgcc ccggcccgcc cgcgcggccc
    21781 gcgcccccgg ccgggcggct caggtcgtac tccaggcgcg cgccggccac ccggccctcg
    21841 aagacgacgc cgatctcgcc gtccttgccg gtctcacgcc gccggccgtc actgctgacg
    21901 agtacgtgcg cgcaggtcag cacccagccg ggcgcgatga acacgccgct gccccacagc
    21961 gggccgggcc cggccccggg cgcggcccgg atgccgacgg tcgcccgtcc ggcctgctcc
    22021 agaagctggg cgtacttctc ccggtcggcc cggtcacggc cttcggaggt cgccatcagg
    22081 tgcccgaatc gccggtgccc tggccgtcac cgccggccgt atcgggctcg cgccgccagg
    22141 tcagggtcac cgagaggttg gccttggcct cgccgtccgc cagcagggcc acggccttgc
    22201 cgggcttggc cgacacctcg accccgaagg tgacgctggt ctcgtgcgga gccacccgct
    22261 gcgcggcctc ccggacgctg gtggcgaccc cgccgatcag ctccctgagc ccctccaccc
    22321 gggtcgtcag cgcctcccag gccccgacgt cctcgaactc gtcgtcctcg ccggtctccc
    22381 ccgggagcgg gacctccagt ctggagaccc gcgcccacac ttccgtcccg tcgggcagtg
    22441 cgatacgtcc cacgcgatcc cgcataacgg cctcctgctc cccctgagcg gcgacatccc
    22501 gaagggcccg tcaccgcagg accgttgaca ggtgatcagg ttagcccccg gccgctggtg
    22561 gcgcgagggg ttccgttacc tgcctatcct gaccgggaat gtcccatgac ccctggtgga
    22621 gagcacgtgt atttcacaga tcgtggcatc gaggaactgg agagccggcg cggtgacgag
    22681 gaggtcaccc tcggctggct ggccgaccag ctccgtacgt tcgtcgacct caacccggac
    22741 ttcgaggtgc cggtcgagcg gctggcgacc tggctggccc ggctcgacga cgaggacgag
    22801 taggagcggg ggaggaacga gggggagggg gaggcgcggc aggaatggag ccggccggac
    22861 ggcccgggac ggccttcagg agcggccacg tgcttgactt cccccaaccg cgatatatcg
    22921 tgtctagcga gacgcgatat gttgcgctgc cgccgtcctg agggaggccc ggaatgtcag
    22981 cccggagcga gtggtcggtc accgaaccac gcacactgga aatcgaggag cccgtcaggg
    23041 aactggacgt gcgcgtggtc agcggcaccg tcaacgtcgt cggcgtcccg gcgggcagcg
    23101 tccccggaag cggcgccgcc cgtgtcgagg tcaccgcact ccacgggccg ccgctgaccg
    23161 tctcgtgccg ggacggggtg ctcagcgtcg gctacaaaga cctcccctgg aagggctggc
    23221 tggacttcgg caagctcaag gggtggcggc gcaccgcggt cgtctcggtg accgtccccg
    23281 ccgccaccgg cgtacgcgtc ggggtcgtcg gggccggcgc ggtgatctcc gggatctccg
    23341 ggcgcacgca gctcaacggc gtctccggcg gcagcacgct cgtcggcctg accggcccgg
    23401 tgcgggccga gaccgtctcg ggcgacgtcc aggcccaggc cgtcaccggt gatctgcgct
    23461 tcagctccgt ctcgggcgac ctcaccgtcg tcgacggcgc cggcgcctcc gtacgggccg
    23521 agtccgtcag cggcgacatg gtcctggacc tcgacctgcc gcccgccgcc ggaccgggcg
    23581 gcaccggccg tacggacgtc aagctcacca ccgtctccgg cgaggtcgcc atccggctgc
    23641 ccgacccggc cgacgcccag gtcgacgccc aggtcgaggc gaacaccacc agcggcacgg
    23701 tcgccaacgc ctttgaggac ctgcgcgtca gcggccagtg gggggccaaa cgcatcaccg
    23761 gccggctcgg cgcgggcaac ggcaggctgg aggtcaccac cgtctccggc gggctggccc
    23821 tgctgcgccg cccgccgtcg cacgacggcc cggtgcgcca cggtgacacc gatgagaccc
    23881 ccgccgacaa gaaggtgctg taagccatgc cccctgtctt cgcccacggc cgtctgcgcc
    23941 tgtacctcct caagctgctg gacgaggccc cgcgccacgg ctacgagatc atccgcctcc
    24001 tggaggagcg cttccagggg ctgtacgcac cctccgcggg caccgtctat ccgcggctgg
    24061 ccaagctgga ggccgagggc ctggtcaccc acaccaccga aggcggacgc aaggtctact
    24121 cgatcaccga cgccggacgg gccgaactgg ccgaccgcgg cggtgagctg gcggaactgg
    24181 agctggagat ccgcgagtcg gtggccgcgc tggcctccga catccgcgag gacgtgagcg
    24241 gctcggtgcg ggacctgcgc cgggagatcc gcgaggcggc gcagcggacc cgcaaggagt
    24301 cgcgggccgg ggccggcgcg ggggcggccg ggggccgggg caggcgtcgg cggcgaggcc
    24361 cgtacgggcg ggggccgtac gggcgggggc gcggacgccg gagacgagcc gggtagcggc
    24421 tacgggaaca gctccggcgg gcgggccggc ttccccgacg cctcggactt cttcgacggg
    24481 gccctgggcg acaaggaggc gtggcggcag gccaaggagg agttccggcg cgccaaggag
    24541 gagtggaagg agcaggcgcg gcgggccaag gaggagagcc ggcgcgccaa acaggaggcc
    24601 cagcgggcac gcaagcaggc ccgggacgcc caggacttcg cgcgcgagga gatccagcgc
    24661 gtccttggcc gcgtacagga acagacgcag gagcacctgc gcaccggcga ctggtcgggg
    24721 gcggcccggg aggcgctggc ggagttctcg cgcgagttcg ggcgcttcgc gggcgggccg
    24781 ttcggggcga cgggcgctcc ggccggggac cagggcggcc cagaagggca ggagggccca
    24841 gaagggcagg agggcccaga agggcaggag ggcccagaag ggcagggggc cagggcggtc
    24901 acggcggccc cggcgatgag agcggcggcc cgcagccccg tacggagcgg gccggtgcgg
    24961 agcggacccg tacggagagg actggtgcgg agcggacccg tacggagcgg gtcgatctgg
    25021 acaaggacgg cgccacggac gggccggccg cgaccgcgcc cgtcgccact cccccgctcc
    25081 ccgcgtgggc gcaggagccc gccaccggcg acccgggccg cgacttcg
//
