LOCUS       NZ_CP074380            25719 bp    DNA     linear   CON 27-MAY-2024
DEFINITION  Streptomyces sp. MST-110588 chromosome, complete genome.
ACCESSION   NZ_CP074380
VERSION     NZ_CP074380.1
KEYWORDS    RefSeq.
SOURCE      Streptomyces sp. MST-110588
  ORGANISM  Streptomyces sp. MST-110588
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1  (bases 1 to 7915503)
  AUTHORS   Booth,T.J., Bozhueyuek,K.A.J., Liston,J.D., Lacey,E. and
            Wilkinson,B.
  TITLE     Bifurcation drives the evolution of assembly-line biosynthesis
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 7915503)
  AUTHORS   Booth,T.J., Bozhueyuek,K.A.J., Liston,J.D., Lacey,E. and
            Wilkinson,B.
  TITLE     Direct Submission
  JOURNAL   Submitted (10-MAY-2021) Molecular Microbiology, John Innes Centre,
            John Innes Centre, Norwich, Not US or Canada NR4, United Kingdom
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: 28-FEB-2016
            Assembly Method                   :: HGAP v. 3.0
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 25.0x
            Sequencing Technology             :: PacBio RSII
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_022695595.1-RS_2024_05_27
            Annotation Date                   :: 05/27/2024 05:38:09
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 6,918
            CDSs (total)                      :: 6,828
            Genes (coding)                    :: 6,327
            CDSs (with protein)               :: 6,327
            Genes (RNA)                       :: 90
            rRNAs                             :: 7, 7, 7 (5S, 16S, 23S)
            complete rRNAs                    :: 7, 7, 7 (5S, 16S, 23S)
            tRNAs                             :: 66
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 501
            CDSs (without protein)            :: 501
            Pseudo Genes (ambiguous residues) :: 0 of 501
            Pseudo Genes (frameshifted)       :: 350 of 501
            Pseudo Genes (incomplete)         :: 185 of 501
            Pseudo Genes (internal stop)      :: 14 of 501
            Pseudo Genes (multiple problems)  :: 45 of 501
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 12:56:23
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 681606
            Orig. end                         :: 707325
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP074380.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            Bacteria and source DNA available from Barrie Wilkinson, John Innes
            Centre, Norwich.
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..25719
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene"
                     /region_number="7"
                     /rules="(PT_phytoene_like or phytoene_synt or Lycopene_cycl
                     or Lycopene_cycl_fung or T1TS or T1TS_KS or T2TS or TS_UbiA
                     or TS_Pyr4)"
                     /tool="antismash"
     cand_cluster    1..25719
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /kind="single"
                     /product="terpene"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..25719
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:15719]"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..15719
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
     misc_feature    complement(803..818)
                     /note="TFBS match to ClgR, Caseinolytic protease gene
                     regulator, confidence: weak, score: 21.79"
                     /tool="antismash"
     gene            complement(843..1904)
                     /locus_tag="KGS77_RS03015"
                     /old_locus_tag="KGS77_02955"
     CDS             complement(843..1904)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018540013.1"
                     /locus_tag="KGS77_RS03015"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KGS77_02955"
                     /product="OB-fold nucleic acid binding domain-containing
                     protein"
                     /protein_id="WP_242587267.1"
                     /transl_table=11
                     /translation="MLSAPLVVEFPFTRSLGPVQSAFLTGLRERTVLGVRGSDGRVVVP
                     PVEYDPVTAEEIRELVEVAPTGTVTTWAWNPSPRRGQPLATPFAWVLVRLDGADTALLH
                     ALDAPGPQAVRTGMRIRVRWAAQRTGSITDIACFETYETSGETSGETSGTGGTSETGRT
                     SRGGGVDGAGGTGETQEPYEGQAAREAAAAHTGEFADAVTTITTPARLDYTYTPGRAQS
                     RYLTALAGRRIVGERCPSCRKVYVPPRGACPTCGIATAEEVGVGPAGTVTTFCVVNIKA
                     RNLDIEVPYVYAHIALDGADLPLHARIGGIPYDQVRMGLRVTPVWAEGERHPDHFRPTG
                     EPDADYDSYKELI"
     gene            complement(2052..2927)
                     /locus_tag="KGS77_RS03020"
                     /old_locus_tag="KGS77_02960"
     CDS             complement(2052..2927)
                     /GO_function="GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /NRPS_PKS="Domain: ECH (12-283). E-value: 6.2e-35. Score:
                     112.6. Matches aSDomain:
                     nrpspksdomains_KGS77_RS03020_ECH.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1023: enoyl-CoA hydratase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018090683.1"
                     /locus_tag="KGS77_RS03020"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KGS77_02960"
                     /product="enoyl-CoA hydratase-related protein"
                     /protein_id="WP_242578549.1"
                     /transl_table=11
                     /translation="MEGTEHLTVERVGATLVLTLNRPEAKNALSLPMLVGLYDGWLAAD
                     EDDTVRSVVLTGAGGCFCAGMDLKALAGNGGASGFGGRAEAGGEAGPEGGAGTGGPMGD
                     PYRDRLKADPDLHWKAMLRHHRPRKPVIAAVEGHCVAGGTEILQGTDIRVAGESAVFGL
                     FEVARGLFPIGGSTVRLARQIPHTHALEMLLTGRPYPAREAERIGLIGHVVPDGGALAK
                     ALEIAGRINACGPLAVEAVKASVYESAGMTEAEGLKAELERGLPVFGTEDAKEGSRAFA
                     EKRPPVYRRA"
     aSDomain        complement(2079..2891)
                     /aSDomain="ECH"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_KGS77_RS03020_ECH.1"
                     /evalue="6.20E-35"
                     /label="KGS77_RS03020_ECH.1"
                     /locus_tag="KGS77_RS03020"
                     /protein_end="283"
                     /protein_start="12"
                     /score="112.6"
                     /tool="antismash"
                     /translation="GATLVLTLNRPEAKNALSLPMLVGLYDGWLAADEDDTVRSVVLTG
                     AGGCFCAGMDLKALAGNGGASGFGGRAEAGGEAGPEGGAGTGGPMGDPYRDRLKADPDL
                     HWKAMLRHHRPRKPVIAAVEGHCVAGGTEILQGTDIRVAGESAVFGLFEVARGLFPIGG
                     STVRLARQIPHTHALEMLLTGRPYPAREAERIGLIGHVVPDGGALAKALEIAGRINACG
                     PLAVEAVKASVYESAGMTEAEGLKAELERGLPVFGTEDAKEGSRAFAEK"
     gene            3113..4813
                     /locus_tag="KGS77_RS03025"
                     /old_locus_tag="KGS77_02965"
     CDS             3113..4813
                     /NRPS_PKS="Domain: AMP-binding (8-444). E-value: 6.6e-72.
                     Score: 234.2. Matches aSDomain:
                     nrpspksdomains_KGS77_RS03025_AMP-binding.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) AMP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1002: AMP-dependent synthetase and ligase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014173689.1"
                     /locus_tag="KGS77_RS03025"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KGS77_02965"
                     /product="acyl-CoA synthetase"
                     /protein_id="WP_242578550.1"
                     /sec_met_domain="AMP-binding (E-value: 9.5e-73, bitscore:
                     243.7, seeds: 400, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEYNLADLFESVVDTVPGREALVFLDHPGTGAERRLTYAELDRAA
                     NRLAHHLRDHGITPGAHVGLYLYNGVEYLQTVYACLKIRAVPVNVNYRYVEEELAYLYR
                     DADLAALVFDAEFTGRVAAALPRSGAGAGKLRHLLRVGTPPPDTQEPALAPVPFAEAEA
                     SGSPERGFAPRSPDDRLIIYTGGTTGMPKGVIWRHEDIFFSGMGGGAPTGEPVRHPREL
                     AERVAAGGEGLVFFPTPPLMHGTSTLTVFIAFHYGQKVVLHRKYVPEEVLRTIERERVT
                     SVSLVGDAMLRPLADALAGPLKGADCSSLLSVSSSGAILSETVRNRFAALAPHVLLLNN
                     FGSTESGFTGTATEDSGPDRGFRLRVNARTAVVDPVTHAPVAPGEEGRIALHGHVPLGY
                     YNDPRKTAETFFEADGERWVLLGDMATVGADGVVTVLGRGSQCINSGGEKVYPEEVEQA
                     LKAHPDVYDALVAGIPDDRWGQRVAAVVQLREGCAEMSVANVQAHCRSRLAGYKIPRTV
                     VFTDRIARSPSGKADYRWAKAVAGAGASAAPAGRDGTGAPGGTNGDLTS"
     aSDomain        3137..4444
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_KGS77_RS03025_AMP-binding.1"
                     /evalue="6.60E-72"
                     /label="KGS77_RS03025_AMP-binding.1"
                     /locus_tag="KGS77_RS03025"
                     /protein_end="444"
                     /protein_start="8"
                     /score="234.2"
                     /specificity="substrate consensus: X"
                     /tool="antismash"
                     /translation="FESVVDTVPGREALVFLDHPGTGAERRLTYAELDRAANRLAHHLR
                     DHGITPGAHVGLYLYNGVEYLQTVYACLKIRAVPVNVNYRYVEEELAYLYRDADLAALV
                     FDAEFTGRVAAALPRSGAGAGKLRHLLRVGTPPPDTQEPALAPVPFAEAEASGSPERGF
                     APRSPDDRLIIYTGGTTGMPKGVIWRHEDIFFSGMGGGAPTGEPVRHPRELAERVAAGG
                     EGLVFFPTPPLMHGTSTLTVFIAFHYGQKVVLHRKYVPEEVLRTIERERVTSVSLVGDA
                     MLRPLADALAGPLKGADCSSLLSVSSSGAILSETVRNRFAALAPHVLLLNNFGSTESGF
                     TGTATEDSGPDRGFRLRVNARTAVVDPVTHAPVAPGEEGRIALHGHVPLGYYNDPRKTA
                     ETFFEADGERWVLLGDMATVGADGVVTVLGRGSQCIN"
     CDS_motif       3653..3706
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_KGS77_RS03025_0001"
                     /evalue="7.90E-06"
                     /label="NRPS-A_a3"
                     /locus_tag="KGS77_RS03025"
                     /protein_end="198"
                     /protein_start="180"
                     /score="18.5"
                     /tool="antismash"
                     /translation="IIYTGGTTGMPKGVIWRH"
     CDS_motif       4259..4342
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_KGS77_RS03025_0002"
                     /evalue="3.20E-05"
                     /label="NRPS-A_a6"
                     /locus_tag="KGS77_RS03025"
                     /protein_end="410"
                     /protein_start="382"
                     /score="16.4"
                     /tool="antismash"
                     /translation="PGEEGRIALHGHVPLGYYNDPRKTAETF"
     gene            complement(4831..5364)
                     /locus_tag="KGS77_RS03030"
                     /old_locus_tag="KGS77_02970"
     CDS             complement(4831..5364)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF022216.4"
                     /locus_tag="KGS77_RS03030"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KGS77_02970"
                     /product="PH domain-containing protein"
                     /protein_id="WP_242578551.1"
                     /transl_table=11
                     /translation="MQTIEFRAASRVWQWCAAAVFLVGGVIPACVITFGIGWEEFGRRV
                     FAEPRGSDLREAAIGLLVCVSLSLVGYHYTSGRTCVDAEGIRTRTLLRRRFVPWQEIEG
                     ISVDKGRESYAGRRGTPAYRIRLDLANGRSLCLPAPAHAEFDSALEAVKGEIIRRRNMA
                     TAQDPSSASRASRS"
     gene            5437..6795
                     /locus_tag="KGS77_RS03035"
                     /old_locus_tag="KGS77_02975"
     CDS             5437..6795
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) p450"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1007: cytochrome P450"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF012296.4"
                     /locus_tag="KGS77_RS03035"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KGS77_02975"
                     /product="cytochrome P450"
                     /protein_id="WP_242578552.1"
                     /sec_met_domain="p450 (E-value: 1.4e-15, bitscore: 55.6,
                     seeds: 50, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDLDADLNPDPDADLNPDLDAAPDAKARFLLTPCGQDPHAEARAL
                     RAQGPVVPVELPGGVRAWLVTHQEAGRAVLADDRFVKDIRAWHAWQRGDIPADWPMAPL
                     VTVANMTTATGTDHRRLRAPLAKAFTVRRVERLRPRIEHFTRDLLDDLEATVAAQPDGG
                     PVDLRARFAHPLPIRVICELFGVPESGRPRLRDLCGALFGGAPAGPAEVLAGHRELRSV
                     LAALLADKSAHPGDDLTSALLAAAGNGTEPYADPHENPREGPPDTRALSGPELVDTLLL
                     MIFAGHETTVNLLVSAVHALLTHPGQLALARTGKVPWPAVVEEALRWDPPVGSLPFRYA
                     RCDAEVAGRTIRAGEPVILSYTAFGRDPRQHGPGADRFDITRTPVPHLSFGHGIHHCLG
                     APLARLEAGIALPALFARFPHLALYEPGIPPKRRPTIVFPGYRDLPVLLEPAP"
     gene            complement(6878..7450)
                     /locus_tag="KGS77_RS03040"
                     /old_locus_tag="KGS77_02980"
     CDS             complement(6878..7450)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019984806.1"
                     /locus_tag="KGS77_RS03040"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KGS77_02980"
                     /product="SMI1/KNR4 family protein"
                     /protein_id="WP_242578553.1"
                     /transl_table=11
                     /translation="MIAPDALDALVRLCPPPAEPPPAVDWAQAERALGVALPADYKQLV
                     GTYGDGLFDETIWLLVPDSAYSDCDLHTQAAERDEILADLWEFEDKPAGLLEAGARILP
                     WAFEEGTGAFMYWLVRPGQHPDRWTVLYNEGRGPLWEHHDMGCLAFLLAVLTGTAETEY
                     FGYLYDVLKATEHRFATADQILGASGR"
     gene            complement(7556..8254)
                     /locus_tag="KGS77_RS03045"
                     /old_locus_tag="KGS77_02985"
     CDS             complement(7556..8254)
                     /NRPS_PKS="Domain: Abhydrolase_1 (26-130). E-value: 9e-25.
                     Score: 79.6. Matches aSDomain:
                     nrpspksdomains_KGS77_RS03045_Abhydrolase_1.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Abhydrolase_6"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF00561"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1262: haloalkane dehalogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003982018.1"
                     /locus_tag="KGS77_RS03045"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KGS77_02985"
                     /product="alpha/beta fold hydrolase"
                     /protein_id="WP_242578554.1"
                     /sec_met_domain="Abhydrolase_6 (E-value: 8.1e-22, bitscore:
                     77.5, seeds: 455, tool: rule-based-clusters)"
                     /sec_met_domain="PF00561 (E-value: 2.3e-19, bitscore: 68.7,
                     seeds: 48, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDEVKKVQVADVQLAYRQWGEPDAPPAVLLHCLGEDGEDWRGVVG
                     QLATTHHVYAPDLRGHGRSDWPGEYGFERWRDDVIGFLRALELDRVTLIGHSLGGMTAL
                     LVALDRPDLVDRLILEESPPPRPAEPPQQVPERPGEPLGFDWEAKAAVVAQRNAPDPRW
                     WDGLPEITAPTLVIAGGPESHIPQQHLAEMAALIPDCRLVTIEGAGHLVHEERPLEYLD
                     AVRAFLGPRP"
     aSDomain        complement(7865..8176)
                     /aSDomain="Abhydrolase_1"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_KGS77_RS03045_Abhydrolase_1.1"
                     /evalue="9.00E-25"
                     /label="KGS77_RS03045_Abhydrolase_1.1"
                     /locus_tag="KGS77_RS03045"
                     /protein_end="130"
                     /protein_start="26"
                     /score="79.6"
                     /tool="antismash"
                     /translation="AVLLHCLGEDGEDWRGVVGQLATTHHVYAPDLRGHGRSDWPGEYG
                     FERWRDDVIGFLRALELDRVTLIGHSLGGMTALLVALDRPDLVDRLILEESPPPRPAEP
                     "
     CDS_motif       complement(7934..7984)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_KGS77_RS03045_0001"
                     /evalue="8.30E-05"
                     /label="NRPS-te1"
                     /locus_tag="KGS77_RS03045"
                     /protein_end="107"
                     /protein_start="90"
                     /score="15.2"
                     /tool="antismash"
                     /translation="VTLIGHSLGGMTALLVA"
     gene            8509..9771
                     /gene="paaK"
                     /locus_tag="KGS77_RS03050"
                     /old_locus_tag="KGS77_02990"
     CDS             8509..9771
                     /EC_number="6.2.1.30"
                     /GO_function="GO:0047475 - phenylacetate-CoA ligase
                     activity [Evidence IEA]"
                     /GO_process="GO:0010124 - phenylacetate catabolic process
                     [Evidence IEA]"
                     /NRPS_PKS="Domain: AMP-binding (74-323). E-value: 3.2e-22.
                     Score: 70.6. Matches aSDomain:
                     nrpspksdomains_KGS77_RS03050_AMP-binding.1"
                     /codon_start=1
                     /gene="paaK"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) AMP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1002: AMP-dependent synthetase and ligase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016572852.1"
                     /locus_tag="KGS77_RS03050"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KGS77_02990"
                     /product="phenylacetate--CoA ligase PaaK"
                     /protein_id="WP_242587268.1"
                     /sec_met_domain="AMP-binding (E-value: 7.7e-26, bitscore:
                     89.2, seeds: 400, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTGDELRALQLERLRSSLRHAYENVAFYRESFDRAGVHPEDCRSL
                     ADLTRFPFTVKDDLRAQYPFGMFAVPESEVRRVHASSGTTGRPTVVGYTGRDLDTWAGL
                     VARSIRAAGGRPGHKVHIAYGYGLFTGGLGAHYGAERLGCTVIPASGGMTSRQVQIIRD
                     FRPEVIMVTPSYMLTLLDEFERQGVDPRTTALKVGIFGAEPWTQEMRREIEERFAIDAV
                     DIYGLSEVMGPGVAQECVETKDGLHLWEDHFFPEVVDPLTGEPLPDGEHGELVLTSLTK
                     EAMPVVRYRTRDLTRLLPGTARAAFRRMERVTGRSDDMIILRGVNLFPAQIEEIVLRTP
                     GVAPHFQLRLTREGRMDHLTVRAEARPEATPEARTAAVGQIAREVKNHIGVSVAVEILD
                     PETLERSVGKIKRIHDTRPRD"
     aSDomain        8731..9477
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_KGS77_RS03050_AMP-binding.1"
                     /evalue="3.20E-22"
                     /label="KGS77_RS03050_AMP-binding.1"
                     /locus_tag="KGS77_RS03050"
                     /protein_end="323"
                     /protein_start="74"
                     /score="70.6"
                     /specificity="substrate consensus: X"
                     /tool="antismash"
                     /translation="VRRVHASSGTTGRPTVVGYTGRDLDTWAGLVARSIRAAGGRPGHK
                     VHIAYGYGLFTGGLGAHYGAERLGCTVIPASGGMTSRQVQIIRDFRPEVIMVTPSYMLT
                     LLDEFERQGVDPRTTALKVGIFGAEPWTQEMRREIEERFAIDAVDIYGLSEVMGPGVAQ
                     ECVETKDGLHLWEDHFFPEVVDPLTGEPLPDGEHGELVLTSLTKEAMPVVRYRTRDLTR
                     LLPGTARAAFRRMERVTGRSDDMIILR"
     CDS_motif       9445..9507
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_KGS77_RS03050_0001"
                     /evalue="4.20E-04"
                     /label="NRPS-A_a8"
                     /locus_tag="KGS77_RS03050"
                     /protein_end="333"
                     /protein_start="312"
                     /score="13.1"
                     /tool="antismash"
                     /translation="TGRSDDMIILRGVNLFPAQIE"
     gene            10001..11921
                     /gene="shc"
                     /locus_tag="KGS77_RS03055"
                     /old_locus_tag="KGS77_02995"
                     /pseudo=""
     CDS             10001..11921
                     /GO_function="GO:0051007 - squalene-hopene cyclase activity
                     [Evidence IEA]"
                     /GO_process="GO:0019746 - hopanoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="shc"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: T2TS"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF024640.4"
                     /locus_tag="KGS77_RS03055"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /old_locus_tag="KGS77_02995"
                     /product="squalene--hopene cyclase"
                     /pseudo=""
                     /sec_met_domain="T2TS (E-value: 2.8e-91, bitscore: 305.3,
                     seeds: 58, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTTTADGTSREPRESREPEGPKGPQEPKGPQGPKEPQDSREPRDG
                     VPKAPAAAGNTAVSFAFPPSDGTEEAARRAVLRATGHLLSRQHTEGYWLGVTSTDVSYD
                     AQDLFLRLILGTTDERVTAATGRWIRSRQRADGTWPLAHDAPGHLGTTIQAYVALRLAG
                     DRPEEAHMLRAAAWVREQGGVAAAELIPRVWLAVFGWWSWDDLPEIPPEIIALPARAPL
                     GIYGFASFARMVLVPLAVISAYRPVRPAPFGIGELFAVGDPPARRAPAAPLGSWDGVFE
                     RLNRVLRVYRKAGPRLPRRAAVNACVRWLLERQEAGGDWAGFSPTTVYPVLALYLHGLP
                     LDHPVLKAALTYLEESTVWHEDGVRMVETVQSPVWDTALSVTALTDAGLPAGHPALVGA
                     ADWLLTRQTTRPGDWAVRRPRLAPGGWAFEFDNQNYPDNDDTSEVILALRRVAHPDQAR
                     VDDAVRRGARWTCGMQCRDGGWAAFDADSDSTLSSKLPYMEIGDYCADAPSADVTAHVV
                     EMLSALGRQEDPGTRRGVRWLLDHQEDHGAWFGRWG"
     gene            complement(12237..12476)
                     /locus_tag="KGS77_RS03060"
                     /old_locus_tag="KGS77_03000"
     CDS             complement(12237..12476)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="KGS77_RS03060"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="KGS77_03000"
                     /product="hypothetical protein"
                     /protein_id="WP_242578555.1"
                     /transl_table=11
                     /translation="MAGRDALPLYGANQSALTAAFTLHGPWEHAPLPLAWWAATSALAL
                     LVFHLRTRSYGRPARRSLAAAPETATRSFPPVPG"
     gene            complement(12425..13060)
                     /locus_tag="KGS77_RS03065"
                     /old_locus_tag="KGS77_03005"
     CDS             complement(12425..13060)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="KGS77_RS03065"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="KGS77_03005"
                     /product="hypothetical protein"
                     /protein_id="WP_242578556.1"
                     /transl_table=11
                     /translation="MNRHWAAFAVMLRCSLLGHLRNRLAMLLAGAFIPVWIAVTHVCAS
                     SRTVRFSLDAADTRIVAQANHIGQVTNALGAVTMVSGFMMFMETFKAGELDRRLVLAGY
                     PRLHMLLAKVVALTLVAALLSLYTTTLLYLTLPVRQLAPWLSRSSAPDSPTEASACCWA
                     HWCAGNWRASSSSSCSACSTPACRTRPSKWSTWPAATPFPCTARTSRR"
     gene            complement(13057..13692)
                     /locus_tag="KGS77_RS03070"
                     /old_locus_tag="KGS77_03010"
     CDS             complement(13057..13692)
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010468022.1"
                     /locus_tag="KGS77_RS03070"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KGS77_03010"
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_242578557.1"
                     /transl_table=11
                     /translation="MGAEGRQRQSRLRISGVWKAYGSRQVLRGADLDVPAGALVGVVGE
                     NGAGKSTLLQIAVGRMTPEKGTVLRSGSMGYCPQSAVLNDTFTVMQHLRLFQVAYRLPS
                     LTRAHELMELLAFADCGRRRAGELSGGTRQKLNLLLALMHDPLLLVLDEPYQGFDWDTH
                     QRFWALAAHLRDQGRSIVVVSHLLHDLHHFDAVRQLREGRLVTEELTR"
     gene            complement(13707..14606)
                     /locus_tag="KGS77_RS03075"
                     /old_locus_tag="KGS77_03015"
     CDS             complement(13707..14606)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: TS_UbiA"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ubiA"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003981440.1"
                     /locus_tag="KGS77_RS03075"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KGS77_03015"
                     /product="UbiA family prenyltransferase"
                     /protein_id="WP_242578558.1"
                     /sec_met_domain="TS_UbiA (E-value: 6e-104, bitscore: 345.8,
                     seeds: 15, tool: rule-based-clusters)"
                     /sec_met_domain="ubiA (E-value: 7e-21, bitscore: 73.4,
                     seeds: 9, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTTMTTSAPAALLQTLWREIRLSWLFIRVDRWTTVFPATCFVMAA
                     TVHARLSAGETVVTVAAGALYFWLFVYEHTLANQLVGVEEDRINKPHRPLVTGRSTIRG
                     ARMRLAVVRIAFPAYGYCLGVLKWALMWQILSLLQHEYGWGRHWLGRNLYAGIGVVAQL
                     AAAWEIVTVLTPDAWRWIVTLTITVTFLMSVQDLRDINGDRAVRRSTMPLVFGETRTRV
                     FLCAGFAVGPWAIHHFLMAPTGPHWWVIATDVVLGGLSLLLAARVVLLRGPGHDQRSYR
                     LVEQWYTLALAASIYTLR"
     gene            complement(14655..15719)
                     /locus_tag="KGS77_RS03080"
                     /old_locus_tag="KGS77_03020"
     CDS             complement(14655..15719)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: PT_FPPS_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1182: Polyprenyl synthetase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003981439.1"
                     /locus_tag="KGS77_RS03080"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KGS77_03020"
                     /product="polyprenyl synthetase family protein"
                     /protein_id="WP_242578559.1"
                     /sec_met_domain="PT_FPPS_like (E-value: 3.2e-54, bitscore:
                     182.6, seeds: 145, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSAETLTAESDFFAPRAAIDELLYEFLTEKAQTATVPRQSALALL
                     LRDFITGGKRVRPLLCVAGWHAARGEGDPARIIRLAASIELAHACALIHDDIMDAADSR
                     RGRPTVHRMLADHHPTPSMAERFGISGAILVGDLALVWSDELLHTTPMPDANRTAVLRC
                     VDMARAELIAGQHLDLLTTSDLDVSIETTLTVVRYKTAKYTIERPLQVGAALAGAGQQV
                     LDACTAYGVPLGEAFQLRDDVLGVFGDPAVTGKSRLDDLREGKCTSLIVHALRSAAPHQ
                     AGRLRALIGDPRLGEPEAAEVRTLLTNTGARAAVEQMIEERYRQALGALAAPFPQSAAR
                     TLETVAEAAVHRTA"
     misc_feature    complement(15913..15929)
                     /note="TFBS match to ZuR_variant_2, Zinc-responsive
                     repressor, confidence: weak, score: 16.86"
                     /tool="antismash"
     misc_feature    15913..15929
                     /note="TFBS match to HexR, Glucose-responsive regulator,
                     confidence: weak, score: 18.66"
                     /tool="antismash"
     misc_feature    15916..15929
                     /note="TFBS match to PerR, Peroxide regulator, confidence:
                     weak, score: 13.67"
                     /tool="antismash"
     gene            complement(16269..17114)
                     /locus_tag="KGS77_RS03085"
                     /old_locus_tag="KGS77_03025"
     CDS             complement(16269..17114)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014140876.1"
                     /locus_tag="KGS77_RS03085"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KGS77_03025"
                     /product="VOC family protein"
                     /protein_id="WP_242578560.1"
                     /transl_table=11
                     /translation="MTTTDYAPGTPNWLDLTVPDVEAATAFYGAVFGWRFRSPGPEAHG
                     YGLFQSDGEIVAGVFPQGEEGGRARWNVYFQTPDADALAKTVEQAGGSVRHRPRDVLTV
                     ARTAGFTDPTGADFAVWQPIGVPGLDKVGEANAMSWAELCTTDVATAKAFYRTVFSWEF
                     RDRHLGEGSQDGEGGGGMVYSIARPSGGTQGAGAGGGEGPAAECAGVMQLPEQNITAGS
                     TSQWFPYFGAADCDVTVATATEHGASVLVPAMDVQDSGRMAMLLDPFGATFAVITGATA
                     "
     gene            complement(17309..17440)
                     /locus_tag="KGS77_RS03090"
                     /old_locus_tag="KGS77_03030"
     CDS             complement(17309..17440)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF024591.4"
                     /locus_tag="KGS77_RS03090"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KGS77_03030"
                     /product="hypothetical protein"
                     /protein_id="WP_347404574.1"
                     /transl_table=11
                     /translation="MIAFVRERLAHFKVPKRVLFVDELPRNAAGKVLKRELRDRFGG"
     gene            complement(<17581..18934)
                     /locus_tag="KGS77_RS03095"
                     /old_locus_tag="KGS77_03035"
                     /pseudo=""
     CDS             complement(<17581..18934)
                     /NRPS_PKS="Domain: AMP-binding (13-317). E-value: 5.1e-64.
                     Score: 208.3. Matches aSDomain:
                     nrpspksdomains_KGS77_RS03095_AMP-binding.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) AMP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1002: AMP-dependent synthetase and ligase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014044198.1"
                     /locus_tag="KGS77_RS03095"
                     /note="frameshifted; incomplete; partial in the middle of a
                     contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /old_locus_tag="KGS77_03035"
                     /product="AMP-binding protein"
                     /pseudo=""
                     /sec_met_domain="AMP-binding (E-value: 5.5e-58, bitscore:
                     195.1, seeds: 400, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTGVRSGTVDAVLRRSARRVPGRTAVRYGDRAWTYRELDEAVTAA
                     SVILREGGLADGDRVAAYGHNSDAYLIGFLACARAGLVHVPVNHQLRGGELRYILEHSG
                     SALVLTDPALAHHLPRSVRSMPLRDATGSLLDQVEAWPREGRTMLSAGEVDERELAQLL
                     YTSGTTARPKGAMMTHRALVHEYASAVPALDLKESDRPVHALPLYHSAQLHVFLMPYLA
                     VGARNTILDAPGPYRIFELVEAGRCDSLFAPPTVWAGLCRHPGFAGRDLSGLRKAYYGA
                     SAMPVPVLERLRARLPGLALYNCFGQSEIGPLATVLGPQEHEGGWSRADGRSSSWRPGS
                     PTP"
     aSDomain        complement(17984..18895)
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_KGS77_RS03095_AMP-binding.1"
                     /evalue="5.10E-64"
                     /label="KGS77_RS03095_AMP-binding.1"
                     /locus_tag="KGS77_RS03095"
                     /protein_end="317"
                     /protein_start="13"
                     /score="208.3"
                     /specificity="substrate consensus: Leu"
                     /tool="antismash"
                     /translation="RRSARRVPGRTAVRYGDRAWTYRELDEAVTAASVILREGGLADGD
                     RVAAYGHNSDAYLIGFLACARAGLVHVPVNHQLRGGELRYILEHSGSALVLTDPALAHH
                     LPRSVRSMPLRDATGSLLDQVEAWPREGRTMLSAGEVDERELAQLLYTSGTTARPKGAM
                     MTHRALVHEYASAVPALDLKESDRPVHALPLYHSAQLHVFLMPYLAVGARNTILDAPGP
                     YRIFELVEAGRCDSLFAPPTVWAGLCRHPGFAGRDLSGLRKAYYGASAMPVPVLERLRA
                     RLPGLALYNCFGQSEIGPLATVL"
     CDS_motif       complement(18398..18451)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_KGS77_RS03095_0001"
                     /evalue="1.70E-07"
                     /label="NRPS-A_a3"
                     /locus_tag="KGS77_RS03095"
                     /protein_end="179"
                     /protein_start="161"
                     /score="23.6"
                     /tool="antismash"
                     /translation="LLYTSGTTARPKGAMMTH"
     gene            19093..21552
                     /locus_tag="KGS77_RS03100"
                     /old_locus_tag="KGS77_03040"
     CDS             19093..21552
                     /GO_function="GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /GO_process="GO:0017000 - antibiotic biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010060744.1"
                     /locus_tag="KGS77_RS03100"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KGS77_03040"
                     /product="penicillin acylase family protein"
                     /protein_id="WP_242578561.1"
                     /transl_table=11
                     /translation="MRNRLRKLALAGVVLLTAAAPLPSGAAAAEARTRTHPSADGLSAE
                     IRYTEYGIPHIVAEDYPDLGFGEGWAQAADQVCTLAEGFVTLRGERSRYFGATGAADPA
                     LSSATTNLAGDLYFKGVRESGTVEKLLRQPAPAGPGHEVQELMRGWVAGYNAWLRHNRV
                     TDPACAGKDWVRPVTRLDVAMRGYALAVLGGQGRAVDGITAAQPPAGSATSGPATSGPT
                     TSGPAAPGRTTGSRAAVAAARALFPQDGADMGSNAVAFQGSTTADGRGLLLGNPHYPWS
                     GGRRFWQSQVTIPGELNAAGASLLGSSTISIGHNARVAWSHTVATGVPFSLHRLTPDPA
                     DPTAYLVDGRSEPMKKRTVTVPVQDGTTVTRTQWWTRYGPVLTSLGQLKLPWSRSEVYA
                     VNDPNAVNMRSGDTSLAFSKADGVAGIERALRRTQGLPWTNTVAADAAGHTLYTQAQVL
                     PRGTDDLARRCSTPLGAATYPATGLAVLDGSRSDCAFGSDPDAVQPGIFGPSAVPTLKD
                     APYAENSNDSAWLSNADRPLTGYPRIFGDIGTPRSLRTRGALEDVSAMAARGRLTVADL
                     QRQQFANRAPAGGLAAADTAAACSALPGGTAPDSGGRPVDVREACEVIGHWDRTVRTDS
                     EGALLFDRFWRKLTAKVPPAERWKTPFDPADPVHTPRTLNTAAPGFTTALADAVAELCA
                     AGIPLDAPLGEHQFVVRNGKRIPVPGGTEALGIWNKTEGLWDPAGGGYREVVHGSSYIQ
                     AVGFDGSRCPVARTLLTYSQSSNPLSPHYSDQTELYSAGRMIRERFCEKDILASPELRV
                     VRVHDGR"
     gene            complement(21643..23201)
                     /locus_tag="KGS77_RS03105"
                     /old_locus_tag="KGS77_03045"
                     /pseudo=""
     CDS             complement(21643..23201)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) AMP-binding"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016571725.1"
                     /locus_tag="KGS77_RS03105"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /old_locus_tag="KGS77_03045"
                     /product="acyl-CoA synthetase"
                     /pseudo=""
                     /sec_met_domain="AMP-binding (E-value: 1.2e-14, bitscore:
                     52.4, seeds: 400, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTDESRPPNGFWAQAAADPDRTVLFAPDGERWTADRLHAACNRLV
                     HGLRAAGLERGDAFAVVLPNGVEMLTAYLAASQAGWYLVPVNHHSVGPEIAWILRDSGP
                     RRSSPTSGSPAPCAPPRTRRGCPPDSVTRSARSTDSVRTRISWRAVRVPYPRAAPWAGS
                     "
     gene            complement(23346..24449)
                     /locus_tag="KGS77_RS03110"
                     /old_locus_tag="KGS77_03050"
     CDS             complement(23346..24449)
                     /EC_number="1.13.12.-"
                     /GO_function="GO:0010181 - FMN binding [Evidence IEA]"
                     /GO_function="GO:0016703 - oxidoreductase activity, acting
                     on single donors with incorporation of molecular oxygen,
                     incorporation of one atom of oxygen (internal
                     monooxygenases or internal mixed function oxidases)
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003982012.1"
                     /locus_tag="KGS77_RS03110"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KGS77_03050"
                     /product="nitronate monooxygenase"
                     /protein_id="WP_242578562.1"
                     /transl_table=11
                     /translation="MQTELSNALGIEHAVFGFTPFPAVAAAITRAGGLGVLGAVRYTAP
                     DDLARDLEWMTRHTDGLPYGLDVVMPAKKVEGVTEADVEAMIPPEHRRFVQDVLARYGV
                     PPLREGEASGWRITGWMEQVARGQLDVAFDHPVRLLASALGPPPADVVRRAHDRGVLLA
                     ALAGSPHHARRHKDAGIDIVVAQGYEAGGHTGEIATMVLTPEVVRAVHPLPVLAAGGIG
                     TGEQIAAGLALGAQGVWLGSIWLTTTEASLHSRALTRKLLAAGPGDTVRSRALSGKPAR
                     QLRTAWTDAWDDPAGPGPLPMPLQGLLVADALSRIQKYEVEPLLGTPVGQIVGRMNSER
                     GVREVFDDLTRGFEAAVDRVNRIAGRG"
     misc_feature    24542..24552
                     /note="TFBS match to HypR, L-hydroxyproline utilization
                     repressor, confidence: weak, score: 18.59"
                     /tool="antismash"
     misc_feature    25435..25451
                     /note="TFBS match to GnfM, Regulator of nitrogen-fixation
                     genes, confidence: weak, score: 19.48"
                     /tool="antismash"
     misc_feature    complement(25662..25672)
                     /note="TFBS match to HypR, L-hydroxyproline utilization
                     repressor, confidence: weak, score: 18.59"
                     /tool="antismash"
ORIGIN
        1 caggacctgc tgggaggtga acggcgcgtg caactcggcc gtgtccaccg gccgttggaa
       61 ggctccggcg ttgcgggcgg cgagccgggt ggacggcgag tcggtgaggt cccgtacgcc
      121 caggctgtgc gcctcgatgc ggtggtccat gccgcggatc caggcgggtc ggcgggagtg
      181 ccgccgggcc agccgccggg cggtgtcacc ggcggccagg accaccgccg ccgcgccgtc
      241 atcgaccggt gggcagtccc cggtacgcag cgggtggacg acgtactccc ccatcggtac
      301 ctcgccccgc aggtgggcgt gcggattgcc gtccgccgcc gcgcgggcgc cggccgccac
      361 cgccgccatc gcccgctcgt ccgtcacgcc cgcgtcgatc agcgcccggg cctggagcgc
      421 ggccagcgcc acggagtccg gccacagcgg tgccaggtag tacgggtcga gctggcgggt
      481 cagcacctcg cgcagcgcgc ccggcgagga cttcccgtag gcgtagacca gggcggtgtc
      541 ggcgtcgccg gtcagcaggt gcacccatgc ctcgtacagg gcccaggcgc cgtccgtctc
      601 gacgtgcgac tccgccaccg gcggccaggc ccccaccccg tccagggcca tggtgaagga
      661 gaacgcacgg ccggcgaggt agtcgctgga gcccgagcag atgaagccga tgtcccgggc
      721 cttcagtccg gtctgctcca gtacgtcgtg caggaccggc atcagcatct cggcctcgga
      781 gacctccgaa ctgtcccgga cgtggtcgct ctgggcgaag gcgacgacgg cgacctcacg
      841 catcagatca gctccttgta gctgtcgtag tcggcgtcgg gttcaccggt ggggcggaag
      901 tggtcggggt gccgctcgcc ctcggcccat acgggcgtca cgcgcaggcc catccgtacc
      961 tggtcgtacg ggatgccgcc gatgcgcgcg tggaggggca ggtccgcgcc gtccagcgcg
     1021 atgtgggcgt agacgtacgg gacctcgatg tccaggttgc gggccttgat gttgacgacg
     1081 cagaaggtgg tgacggtacc ggccgggccg accccgacct cctccgcggt ggcgatgccg
     1141 caggtggggc aggcgccgcg gggtggcacg tacaccttgc ggcaggacgg gcagcgctcg
     1201 ccgacgatcc gccgcccggc gagggcggtg aggtagcggg actgggcgcg gccgggggtg
     1261 taggtgtagt ccaggcgggc gggggtggtg atcgtggtga cggcgtcggc gaactctccg
     1321 gtgtgcgccg ctgctgcctc tcgcgccgct tgcccctcgt acggctcttg cgtctcgccc
     1381 gtaccgccgg ccccgtcgac cccgccgccc ctgctggtcc tgcctgtctc gcttgtcccg
     1441 cctgtcccgc ttgtctcacc gcttgtctca ccgctggtct catacgtctc gaagcaggcg
     1501 atgtcggtga tcgatccggt gcgttgcgcc gcccagcgga cgcggatccg catcccggtc
     1561 cgtacggcct gcggtcccgg tgcgtccagg gcgtgcagca gtgcggtgtc ggcgccgtcc
     1621 agccgtacca gcacccaggc gaagggggtg gccaggggct ggccgcggcg cggggagggg
     1681 ttccacgccc aggtggtgac ggtgccggtg ggggcgacct cgaccagttc gcggatctcc
     1741 tcggcggtga cggggtcgta ctcgacgggc ggtacgacca ccctgccgtc actgccccgg
     1801 acgcccagga cggtgcgctc gcgcagcccg gtcaaaaagg cgctctgtac ggggccgagg
     1861 gaacgggtga acgggaactc caccacgagc ggcgccgaga gcacttcgga cgggcgggtc
     1921 cgaggtgtgc gggcctcgga cgtacgggcc tcaggcgggc cggtccggga cgtgtgcgtt
     1981 tcggacgtgc gcgtctcggg tgtgtgcgtc tcgggcgtac gggcctgcgg catgcggacc
     2041 tccgtaaggt gtcaggcgcg ccggtagacg ggcggtcgtt tctccgcgaa ggcccgggag
     2101 ccttccttgg cgtcctcggt gccgaagacg ggcaggccgc gttcgagttc ggccttcagg
     2161 ccctcggcct cggtcatccc cgcgctctca tagacggacg ccttgaccgc ctcgacggcg
     2221 agcgggccgc aggcgttgat ccgcccggcg atctccagcg ccttggccag cgcgccgccg
     2281 tcgggcacca catggccgat cagcccgatc cgctcggcct cacgggccgg gtagggccgt
     2341 ccggtgagca gcatctccag ggcgtgggtg tgcgggatct ggcgggccag gcggaccgtg
     2401 gagccgccga tggggaagag gccgcgggcg acttcgaaga gcccgaagac ggcgctctcg
     2461 ccggccaccc tgatgtccgt gccctggagg atctccgtac cgccggcgac acagtgtccc
     2521 tcgaccgccg cgatcaccgg tttgcgcggc cggtggtggc gcagcatggc cttccagtgc
     2581 aggtcggggt cggccttgag gcggtcgcgg tacggatcgc ccatcggccc tccggtcccc
     2641 gccccgcctt cagggcccgc ctcgcctccg gcttccgccc tgcccccgaa ccccgacgct
     2701 cccccgttcc ccgccagtgc cttgaggtcc attccggcgc agaagcagcc gcccgcgccg
     2761 gtgagcacga ccgagcggac ggtgtcgtcc tcgtcggccg cgagccagcc gtcgtacagg
     2821 cccaccagca tcggcagcga gagggcgttc ttcgcctccg gccggttgag cgtaagcacc
     2881 agtgtcgcgc ccacgcgctc cacggtgagg tgttcggtgc cctccattac atcctcccgc
     2941 cccgtgccgc cttgcgccca cgacggagaa caggttgcag gaggcgcaca ccgacttcaa
     3001 gagtttcctg actaccagtc agattcgttg ctcgggccct cttccaaggg ccgccgcgcg
     3061 gcgctctaat gacggccgag cgcccgacgt ccgcgcccgg tctggaggag acatggagta
     3121 caacctcgcc gacctcttcg aatcggtcgt cgacacggtt cccggccgcg aggcgctggt
     3181 cttcctcgac catcccggta cgggcgccga gcggcgcctg acgtacgcgg aactggaccg
     3241 cgccgccaac cggctcgccc accacctccg tgaccacggc atcaccccgg gggcccacgt
     3301 cggcctgtac ctctacaacg gcgtcgagta cctccagacc gtctacgcct gcctgaagat
     3361 ccgcgccgtc cccgtcaacg tcaactaccg ctacgtggag gaggaactgg cctacctcta
     3421 ccgggacgcg gacctcgccg cgctcgtctt cgacgcggag ttcaccggac gggtggccgc
     3481 cgcactgccc cggtccgggg cgggagccgg gaagctgcgt cacctcctgc gggtgggcac
     3541 acctcccccg gacacccagg aacccgcgct cgcccccgtc ccgttcgccg aggccgaggc
     3601 atccggctcc cccgagcgcg gcttcgcccc ccgttccccc gacgaccggc tcatcatcta
     3661 caccggcggc accaccggga tgcccaaggg cgtcatctgg cggcacgagg acatcttctt
     3721 ctccggcatg ggcggcggcg ccccgaccgg cgagcccgta cggcacccgc gggagctggc
     3781 ggaacgggtc gcggccggcg gcgaggggct ggtcttcttc cccacgcccc cgctgatgca
     3841 cggcacctcc accctcaccg tcttcatcgc cttccactac ggccagaagg tcgtcctcca
     3901 ccgcaagtac gtgcccgaag aggtgctgcg caccatcgag cgggagcggg tcaccagtgt
     3961 ctcgctggtg ggggacgcga tgctgcgccc gctggccgac gcgctcgccg ggcccctgaa
     4021 gggggccgac tgctcctcgc tcctgagcgt cagcagctcc ggcgcgatcc tctcggagac
     4081 cgtacggaac cggttcgccg ccctggcccc gcacgtgctg ctgctgaaca acttcggctc
     4141 gaccgagtcc ggcttcaccg gcacggcgac cgaggactcc ggccccgacc gcggtttccg
     4201 gctgcgcgtc aacgcccgta cggcagtggt cgacccggtg acgcacgcac cggtcgcccc
     4261 cggcgaggag ggccggatcg cgctgcacgg ccacgtaccg ctgggctact acaacgaccc
     4321 ccggaaaacc gccgagacct tcttcgaggc ggacggcgag cggtgggtgc tgctcggtga
     4381 catggcgacc gtcggcgcgg acggtgtcgt caccgtcctg ggccgtggct cgcagtgcat
     4441 caactccggt ggggagaagg tctatccgga ggaggtcgag caggcgctca aggcacatcc
     4501 ggacgtgtac gacgcgctgg tcgcgggaat tcccgacgac cggtggggcc agcgcgtggc
     4561 ggcggtggtc caactgcggg agggctgcgc cgaaatgagc gtggcgaacg tacaggccca
     4621 ctgccgttcc cggctggcgg gctacaagat cccccgtacc gtcgtcttca ccgaccgcat
     4681 cgcacgctcc cccagcggca aggccgacta ccggtgggcg aaggcggtgg cgggggccgg
     4741 ggcgtcagcg gcaccggcgg gccgggacgg tacgggagcg ccgggaggga cgaacgggga
     4801 cctgacgtcc tgagttccgg cgcggtccgc ctacgaccgc gacgcccgcg atgcgctgga
     4861 cgggtcctgc gcggtcgcca tgttccggcg ccggatgatc tcgcccttga ccgcctccag
     4921 agcggaatcg aactcggcgt gtgcgggcgc gggcaggcac aagctcctgc cgttcgccag
     4981 gtcgagccgg atgcggtatg cgggggtgcc ccggcggccc gcgtaggact ccctgccctt
     5041 gtcgacggag atgccctcga tctcctgcca ggggacgaac cgccgacgca gcaacgtccg
     5101 ggtccggatg ccttcggcgt cgacgcaggt acgcccggag gtgtagtggt acccgacgag
     5161 cgagagggac acgcacacca gaaggccgat ggccgcttcc ctcagatcgc tgccccgcgg
     5221 ttccgcgaag acccgccggc cgaattcctc ccagccgatg ccgaacgtga tgacgcacgc
     5281 cgggatgact cctcccacga ggaagacggc ggcggcacac cactgccaca cacgggacgc
     5341 agcacggaat tcgatcgttt gcacggtttc accctacgct ccgggtgctg tccgttccca
     5401 agcccgcggc agccgcctcc cgttctagac tggaacatgg acctggatgc ggacctgaac
     5461 ccggaccctg atgcggacct gaacccggac ctggacgcgg ccccggacgc caaggctcga
     5521 ttcctgctga ccccatgcgg gcaggacccg catgcagagg cacgggcgct ccgtgcgcag
     5581 ggtcccgtcg tccccgtgga actgcccggt ggcgtacggg cctggctggt gacccatcag
     5641 gaggccggcc gcgcggtact ggccgacgac cgcttcgtga aggacatcag ggcgtggcac
     5701 gcctggcagc gcggcgacat cccggccgac tggccgatgg cgccgctggt caccgtcgcc
     5761 aacatgacca ccgccaccgg caccgatcac cgacggctgc gcgcgccgct ggccaaggcg
     5821 ttcaccgtac gccgcgtgga gcgactgcgt ccccgtatcg agcacttcac ccgcgacctc
     5881 ctggacgacc tggaagccac cgtcgccgca cagccggacg gcggcccggt ggacctgcgg
     5941 gcgcgcttcg cccatccgct ccccataagg gtgatctgcg agctgttcgg cgttccggag
     6001 agcgggcggc cccggctgcg ggacctgtgc ggcgccctgt tcggcggcgc gcccgccggc
     6061 ccggccgagg tactcgccgg ccaccgggaa ctgcgttccg tactcgccgc cctgctcgcc
     6121 gacaagagcg cgcatccggg cgacgacctg accagcgcgt tgctggccgc ggcggggaac
     6181 ggaaccgaac cctacgcaga tcctcacgaa aacccccgcg aaggcccccc ggacacccgt
     6241 gcgctcagcg ggccggagct cgtggacacc ctgctgctga tgatcttcgc cggtcatgag
     6301 accaccgtga acttgctggt gagcgccgtt cacgcgctgc tcacccaccc cggccagctc
     6361 gccctggccc gtaccgggaa ggtgccgtgg cccgcggtgg tcgaggaggc gctgcgctgg
     6421 gatcctccgg tgggcagcct gccgttccgc tatgcccggt gcgacgcgga ggtggccggc
     6481 cgcaccatcc gtgcgggcga gcccgtcata ctctcctata cggccttcgg ccgtgacccg
     6541 cgacagcacg gccccggcgc cgaccgcttc gacatcaccc gtacacccgt cccgcatctg
     6601 tcgttcggcc acggcatcca ccactgcctc ggcgcgccac tggcccgcct ggaagccgga
     6661 atcgccctcc ccgccctctt cgcccgcttt ccccacctcg ccctctacga acccgggatc
     6721 ccgccgaagc gccgccccac catcgtcttc cccggctatc gcgacctgcc ggtcctcctg
     6781 gagccggctc cctgacccca ccaccgcccg ccctgggtgc cggaactggt cgtggtccac
     6841 gcgtccggga ccggtcgtcg agagtggccg cacgacgtca gcgcccggaa gctcccagga
     6901 tctgatcggc cgtcgcgaaa cggtgctccg tcgccttcag cacgtcgtag aggtagccga
     6961 agtactccgt ttccgccgtt cctgtgagca ccgccaacag gaaggcgagg caccccatgt
     7021 cgtggtgctc ccacagcggg ccgcgcccct cgttgtagag cacggtccac cggtcggggt
     7081 gctgaccggg ccgcaccagc cagtacatga acgcccccgt gccctcctcg aaagcccacg
     7141 gcaggatgcg cgcccccgcc tccagcaggc cggcgggctt gtcctcgaac tcccacaggt
     7201 cggccaggat ctcgtcccgc tccgcggcct gggtgtgcag gtcacagtcg ctgtaggcgg
     7261 agtcgggaac gagcagccag atcgtctcgt cgaagaggcc gtcgccgtat gtaccgacga
     7321 gttgcttgta gtcggcgggc agagccacac ccaaggcacg ctctgcctgc gcccagtcca
     7381 ccgcgggcgg cggttcggcg ggcggcgggc agaggcggac gagggcatcg agggcatcgg
     7441 gggcgatcat gaaacggacg ctactggtgc cccggccggt gaccgtgggc gggggacagg
     7501 caggcgaaga gccgcccggg aacccggcag ccccactccc gcacttgccg ggtgcctacg
     7561 gccgggggcc gaggaaggcg cgtacggcgt cgaggtattc cagggggcgt tcctcgtgga
     7621 cgagatggcc ggcgccttcg atggtcacga gccggcagtc ggggatcagg gcggccatct
     7681 cggcgaggtg ctgctgcggg atgtggctct ccggtccgcc ggcgatgacc agagtcggtg
     7741 cggtgatctc cggcaggccg tcccaccagc gcgggtcggg ggcgttgcgc tgggccacca
     7801 ccgcggcctt cgcctcccag tcgaagccca gcggctcccc gggccgttcg gggacctgct
     7861 gcgggggttc ggccgggcgg ggcggtggcg actcctccag gatcagccgg tccaccaggt
     7921 ccggccggtc gagggcgacc agcagggcgg tcatgccgcc cagcgagtgg ccgatcagcg
     7981 tgacccggtc cagctccagc gcccggagga agccgatcac gtcgtcccgc cagcgctcga
     8041 agccgtactc cccgggccag tcgctcctgc cgtgcccccg gaggtccggc gcgtacacgt
     8101 gatgggtggt ggcgagctgg ccgaccacgc cccgccagtc ctcgccgtcc tcgccgaggc
     8161 agtgcagcag caccgccggc ggcgcgtccg gctcccccca ttgccggtat gccagttgaa
     8221 cgtctgctac ctgcaccttc ttcacctcgt ccatggaccc acggtactca gcgcatcatc
     8281 ggacacaccc cttgacgccg ttcgccgggc gctgattatt tggaccggca ctcggcgacc
     8341 gaatgatcgg tcggcccgat gggcgggcac gtacgcatac aggacgcacg tacggataca
     8401 ggacggtgga cttccatgac ggcgacgagc ggggacgggg accagcgcgg ggacagcggt
     8461 gggggcagca gcggtacggg cgtggccgcg ttcgacgacg gggagcggct gaccggggac
     8521 gagctgcggg cgctccaact ggagcggctg cgctcctcgt tgcggcacgc gtacgagaac
     8581 gtcgccttct accgggagtc cttcgaccgg gcgggcgtcc accccgagga ctgccgctcc
     8641 ctcgccgatc tgacgcgctt ccccttcacc gtcaaggacg acctgcgtgc ccagtacccc
     8701 ttcgggatgt tcgccgtccc cgagtccgag gtgcggcgcg tccacgcctc cagcgggacg
     8761 accggccgcc ccacggtcgt cggctacacc ggacgcgacc tggacacctg ggccggtctc
     8821 gtcgcccgct cgatccgggc agccggcggc cggcccggcc acaaggtgca catcgcgtac
     8881 gggtacgggc tgttcaccgg cggcctggga gcgcattacg gggccgaacg gctcggctgt
     8941 accgtgatcc cggcttccgg gggcatgacg agccgccagg tccagatcat ccgggacttc
     9001 cgcccggagg tcatcatggt gacgccttcc tacatgctca ccctgctgga cgagttcgag
     9061 cggcagggcg tcgatccccg tacgaccgct ctgaaggtcg gcatattcgg tgccgagccg
     9121 tggacgcagg agatgcgccg cgagatcgag gagcggttcg cgatcgacgc ggtggacatc
     9181 tacggcctct cggaggtgat ggggccgggt gtggcgcagg agtgcgtgga gaccaaggac
     9241 ggcctgcatc tgtgggagga ccacttcttc cccgaggtcg tcgatccgct caccggtgag
     9301 ccgctgcccg acggcgagca cggcgagctg gtcctcacct cgctgacgaa ggaggcgatg
     9361 ccggtcgtgc gctaccgcac gcgcgatctg acccggctgc tgcccggtac cgcgcgcgcc
     9421 gccttccgcc gtatggagag ggtcaccggg cgcagcgacg acatgatcat cttgcgtggg
     9481 gtcaatctct tcccggccca gatcgaggag atcgtcctgc gtacgccggg ggtggcgccg
     9541 cacttccagc tccggctgac ccgcgaggga cggatggacc acctgaccgt acgggccgag
     9601 gcccgcccgg aggcgacccc ggaagcccgt acggccgccg tcgggcagat cgcccgcgag
     9661 gtgaagaacc acatcggcgt ctcggtggcc gtcgagatcc tcgatccgga gaccctggaa
     9721 cgctccgtcg gcaagatcaa gcggattcac gacacccgcc cccgggactg accgccctgc
     9781 cgcgtgacag gtgtggcacg catgccacgt acagcacgca taacacacat aacacgtatg
     9841 gcgcgtatgg caggtatggg ctgttttgtg gcgactgtgc ctgggaatgg tgtgtccgcg
     9901 gcgccccggt tccggcggtc tcccgccgtc ggcggcgtcc ggatgtccga ccaccagtga
     9961 cgtccagcag cgacgtccac cagtgatgcg caggggtgcc atgacgacca cggccgacgg
    10021 tacgtcccgg gagcccaggg aatccaggga acccgagggg cccaagggac cgcaggagcc
    10081 caagggaccg cagggcccca aggagcccca ggattcccgc gaaccccggg acggtgtccc
    10141 caaggccccg gccgccgcgg ggaacaccgc ggtgagcttc gccttccccc cgtccgacgg
    10201 gacggaggaa gcggcccggc gcgcggtgct gcgggccacc ggccacctgc tgtcgcggca
    10261 gcacaccgag ggctattggc tgggcgtcac ctcgaccgac gtctcctacg acgcccagga
    10321 cctgttcctg cgcctgatcc tggggaccac ggacgagcgc gtcaccgcgg cgaccggccg
    10381 gtggatccgt tcgcggcagc gcgcggacgg cacctggccg ctcgcccacg acgctcccgg
    10441 tcacctgggg accaccatcc aggcgtacgt ggccctccgc ctcgccggag accgcccgga
    10501 ggaggcccat atgctccggg ccgcggcgtg ggtccgcgag cagggcggcg tcgcagccgc
    10561 cgaactgatc ccccgtgtct ggctcgccgt gttcggctgg tggagctggg acgacctgcc
    10621 cgagatcccg ccggagatca tcgcgctgcc ggcccgggcg ccgctgggca tctacggctt
    10681 cgcctccttc gcccgtatgg tgctggtgcc gctggcggtc atcagcgcct accggcccgt
    10741 gcggccggcg cccttcggca tcggggaact gttcgccgtc ggcgacccgc cggcccgcag
    10801 ggcgccggcc gccccgctcg gcagttggga cggcgtcttc gagcggctga accgtgtgct
    10861 gcgcgtctac cgcaaggccg gcccccgctt gccgcggcgg gcggcggtga acgcctgtgt
    10921 ccgctggctc ctcgaacgcc aggaggcggg cggtgactgg gccggtttca gtccgacgac
    10981 cgtgtacccg gtcctcgccc tgtacctgca cggcctcccc ctggaccacc ccgtactcaa
    11041 ggccgccctg acctacttgg aggagagcac ggtctggcac gaggacggcg tgcggatggt
    11101 ggagacggtc cagtccccgg tctgggacac cgccctgtcc gtcaccgcgc tcaccgacgc
    11161 gggcctgccg gccggtcacc cggcgctggt gggggccgcg gactggctgc tcacccggca
    11221 gaccacccgg cccggtgact gggccgtacg gcggccccgg ctcgccccgg gcggctgggc
    11281 cttcgagttc gacaaccaga actaccccga caacgacgac acctccgagg tgatcctcgc
    11341 gctgcgccgg gtcgcccacc ccgaccaggc gcgggtcgac gacgcggtac gcagaggggc
    11401 gcggtggacc tgcggcatgc agtgccggga cggcgggtgg gccgccttcg acgccgacag
    11461 cgacagcacc ctctccagca agctgcccta catggagatc ggtgactact gtgcggacgc
    11521 gcccagcgcc gacgtcaccg cgcacgtggt ggagatgctg tccgccctcg ggcggcagga
    11581 ggaccccggc acccggcgcg gtgtccgctg gctgctggac caccaggagg accacggcgc
    11641 gtggttcgga cgctgggggt gaaccacgtg tacggcaccg gctgcgccgt cccggccctc
    11701 accgccgccg gtgtaccggc cggccacccg gccgtccggc gcgccgtcgg atggctggaa
    11761 tccgtacaga acaccgacgg cggctggggg aggacctgcg ctcgtacgag gatccggcgt
    11821 acctcggcaa gggcccgtcc acgccgtcgc agacggcctg ggcgctgctg gcgctgctgg
    11881 ccgcgggaga gcgggagggg gccgcggtcc gcgcggggtg acctggctga ccgagcggca
    11941 gacggaggcc ggcacctggg aggagtcgct ggtcaccggc atgggagtcc ccgggtcagc
    12001 atcatgaagt acggccttta cccccatgtc ttcccgctta cggccctggg ccgctacgcc
    12061 cggcggcagc gcaccggagc cctgacggac gtgcccgcgc cggactgaca ccgtcggctc
    12121 caccgccttg gcccgtacga cgccaggacc gtacgacgtc aggacccgta cgacgtcagg
    12181 acccgtaagc cggcaggacc gtacgaccgc gcacggggcg aggccacgaa aggccgctac
    12241 cccggcaccg gcgggaagga ccgggtggcc gtctccggcg ccgcggccag cgacctcctg
    12301 gcgggtctgc cgtaggagcg ggtacggagg tggaagacga gcagggccag ggcgctggtc
    12361 gccgcccacc aggcgagcgg cagcggcgcg tgctcccagg gaccgtggag ggtgaaggcc
    12421 gcggtcagcg ccgactggtt cgcgccgtac aggggaaggg cgtcgcggcc ggccatgtcg
    12481 accacttcga gggtcgggtt ctgcaggccg gtgtcgagca ggctgagcat gatgacgagg
    12541 aagaagccct ccagttcccc gcgcaccagt gagcccagca gcaggccgat gcctccgtag
    12601 gcgagtccgg cgccgaggac cgcgagagcc agggggccaa ctgccgtacg ggcagcgtca
    12661 ggtacagcag ggtggtggtg tagagggaca ggagggcggc gaccagggtg agggcgacga
    12721 ccttggccag cagcatgtgg agccgggggt agccggccag caccagccgg cggtccagtt
    12781 ccccggcttt gaacgtctcc atgaacatca tgaagccgct gaccatcgtc acggcgccga
    12841 gcgcgttggt cacctgcccg atgtggttcg cctgggcgac gatccgggtg tccgcggcgt
    12901 ccagggagaa acgtaccgtc cggctggagg cgcacacgtg ggtcacggcg atccatacgg
    12961 ggatgaacgc tcctgccagg agcatggcaa ggcggttgcg cagatgaccc agcagggagc
    13021 agcgcagcat cacggcgaag gccgcccagt gacggttcat cgggtgagct cctcggtgac
    13081 gaggcggccc tcgcgcaact ggcggaccgc gtcgaagtgg tggaggtcgt gcagcaggtg
    13141 cgagaccacg acgatcgacc ggccctggtc gcgcaggtgg gcggccaggg cccagaagcg
    13201 ctggtgggtg tcccagtcga agccctggta gggctcgtcc agcaccagga gcagcgggtc
    13261 gtgcatgagg gcgagcagca ggttgagctt ctgccgtgtc cctccgctga gttctccggc
    13321 gcgccggcgc ccgcagtcgg cgaacgccag cagctccatc agctcgtggg cccgggtcag
    13381 ggacggcagc cggtaggcga cctggaacag ccgcaggtgc tgcatgacgg tgaacgtgtc
    13441 gttcagtaca gcgctctgcg gacagtagcc catcgatccg ctccgcagga ccgttccctt
    13501 ctcgggtgtc atccgcccca cggcgatctg gagcagcgtg ctcttgcccg cgccgttctc
    13561 cccgacgacg ccgaccagcg ccccggcggg cacgtcgagg tcggcgccgc gcagcacctg
    13621 tctgctgccg tacgccttcc acaccccgct gatccgcagc cgtgactgcc gttgtctgcc
    13681 ctctgccccc actcgggccc ccttggtcag cgaagtgtgt agatggaagc ggcaagcgcg
    13741 agggtgtacc actgttccac caggcggtag ctgcgctggt cgtgtccggg gccgcgcagc
    13801 agcaccaccc gggcggccag cagcaggctc aggccgccca ggaccacgtc cgtggcgatg
    13861 acccaccagt gcgggccggt gggcgccatg aggaagtggt ggatggccca ggggccgacg
    13921 gcgaaaccgg cgcacaggaa gacgcgggtg cgggtctctc cgaagaccag gggcatggtg
    13981 gagcggcgga ccgctcggtc accgttgatg tcgcggagat cctggacgga catgaggaag
    14041 gtcacggtga tcgtcagcgt cacgatccag cgccaggcgt ccggcgtgag tacggtgacg
    14101 atctcccacg cggctgccaa ctgggcgacg acgccgatcc cggcgtagag attcctgccc
    14161 agccagtggc ggccccaacc gtactcgtgc tggagcaggg agaggatctg ccacatcagg
    14221 gcccacttca ggacgcccag gcagtagccg tacgcgggga aggcgatccg cacgacggcc
    14281 agccgcatgc gggcgccgcg gatggtgctg cggccggtga ccaggggccg gtggggcttg
    14341 ttgatgcggt cctcttcgac gccgacgagc tggttggcca gggtgtgctc gtagacgaac
    14401 agccagaagt acagcgctcc cgcggcgacg gtgaccacgg tttcccctgc ggacaggcgg
    14461 gcgtggacgg tggccgccat gacgaagcag gtggcgggga agacggtggt ccagcggtcg
    14521 acgcggatga acagccagct caggcggatc tcccgccaga gtgtctgcag caacgccgcg
    14581 ggagcgctcg tcgtcatggt cgtcattgct tggctccgta ctcgggcagg cggatcacgg
    14641 cccgcttcct cccctcatgc cgtgcggtgg acggccgcct ccgcgacggt ctccagcgtg
    14701 cgggccgcgc tctgcgggaa gggggcggcc agggcgccga gcgcctgccg gtaccgttcc
    14761 tcgatcatct gctcgaccgc ggcccgggct ccagtgttcg tgaggagggt gcggacctcc
    14821 gcggcctcgg gctcccccag tcgggggtcg ccgatcagcg cgcgcagccg gccggcctgg
    14881 tggggggcgg cggagcgcaa ggcgtggacg atgaggctgg tgcacttgcc ctcgcgcagg
    14941 tcgtccaggc gggacttgcc cgtcacggcc gggtcgccga agacgcccag gacgtcgtcg
    15001 cggagctgga aggcttcccc gagcggtacg ccgtaggcgg tgcaggcgtc caggacctgc
    15061 tgtccggcac cggcgagggc ggcgcccacc tgcagggggc gttcgatggt gtacttcgcc
    15121 gtcttgtagc gcacgacggt cagcgtcgtc tcgatgctga cgtcgagatc gctggtggtg
    15181 agcaggtcca gatgctggcc ggcgatgagt tcggcgcgcg ccatgtccac gcagcgcagt
    15241 acggccgtcc ggttggcgtc gggcatcggc gtggtgtgca gcagttcgtc ggaccagacg
    15301 agggcgaggt cgcccacgag gatggcaccg ctgatgccga aacgttccgc catcgagggc
    15361 gtggggtggt ggtcggccag catgcggtgc acggtcgggc gtccgcgccg gctgtcggcg
    15421 gcgtccatga tgtcgtcgtg gatgagcgcg caggcgtgcg ccagttcgat ggaagcggcc
    15481 agcctgatga tccgcgcagg gtcgccctcc cctcttgccg cgtgccatcc ggccacgcac
    15541 agcagggggc ggacccgttt cccgccggtg atgaagtccc gcagcagcag ggcgagcgcc
    15601 gactgacggg gcaccgtcgc ggtctgcgcc ttctccgtca ggaattcgta cagaagctcg
    15661 tcgatcgccg cacgcggagc gaagaagtcg gactcggctg tcagcgtttc agcactcatg
    15721 agaagaggcg catcccgggt ccgagggtca tccaccggtt tctggttctg cggcgaaagg
    15781 cgcccggcgg ggccggagtt cgccggacgg actcactgtc cattcatcgc atccctgggt
    15841 cgacgcccgc gctgagccat acggaagcac gggcaaaaca gtttcgaccg aagctacgcc
    15901 tcatcaaggg atatgtccat ttattaccac tttctcagca tttcgccttt cgtggcgagg
    15961 gcgccgactc cggccgaatg tccggcgcca ccagggacgc cgcagtccat aggatccggt
    16021 ccggcgccgc cgcccctcct cgaccgaccg gagcagccgg ttcgaaggag gaacggcggg
    16081 atgacggaac cccgcattcc acacggggcg cgcgagccgc acccgcactc gccccgtaca
    16141 cacgctcccg tggtcgcccg ttcgacgatg tagtacgagg tggcggcgcc gagcgggacg
    16201 gggggcctgg cgcggggcag gggcgggcat ttgggcgcgg gggaccgctg gacgcggggg
    16261 gccgtgcatc aggcagtggc gcccgtgatg acggcgaagg tggcaccgaa ggggtccagg
    16321 agcatggcca tacggccgct gtcctgcacg tccatggcgg gcacgagcac cgacgcaccg
    16381 tgctcggtgg ccgtggcgac cgtgacatca cagtcggcgg cgccgaagta cgggaaccac
    16441 tgcgacgtcg atcccgcggt gatgttctgc tcgggcaact gcatcacgcc ggcgcattcg
    16501 gccgccggcc cttctccccc tcccgctccc gctccttgcg tgccgccgga cggcctggct
    16561 atggaataga ccatgccccc gccgccctcg ccgtcctggc tgccctcgcc cagatgccgg
    16621 tcgcggaact cccaggaaaa gaccgtgcgg tagaacgcct tggccgtggc cacgtcggtc
    16681 gtgcacagct cggcccagct catcgcgttc gcctcaccga ccttgtccag ccccgggacg
    16741 ccgatgggct gccagacggc gaaatcggcc ccggtcgggt cggtgaaacc cgcggtacgg
    16801 gcgacggtga ggacgtcccg cggccggtgg cggacgctgc ccccggcctg ctccaccgtc
    16861 ttggccaggg cgtccgcgtc cggggtctgg aagtacacgt tccacctggc gcgcccgccc
    16921 tcctccccct gcggaaagac cccggcgacg atctcgccgt ccgactggaa gaggccgtag
    16981 ccgtgcgcct ccgggccggg cgaccggaac cgccacccga acaccgcgcc gtagaaggcg
    17041 gtggcggcct cgacgtcggg gaccgtcagg tccagccagt tcggcgtacc cggggcgtaa
    17101 tcggttgtgg tcatgatggg tgctcctccg actcgtagcc gtgacacggc gcgccccccg
    17161 ggcgagcacg gacacaccgc gtccttcagg tgttcctcaa cggtggcgga cacggcccgg
    17221 cgagccgcgc accggcggcc ccgtcccgtt cccgccggcg tctctcagca tggcaggggg
    17281 gtccgacaat cgtccccgcg cgccctcctc agccgccgaa ccggtcccgc agctcccgtt
    17341 tgaggacctt tccggcggcg ttgcgcggca gttcgtccac gaagagcacc cgcttgggga
    17401 ccttgaagtg cgcgagccgt tcccgtacga aggcgatcag ctcccgcgcg agaggggccg
    17461 tccgccgctc gtcttctccg ttcccctcct ctccttcgct cctcccggcc cggccgtcct
    17521 cctcgtcccc tcaccccgtc cgtcccgctc ctcccccggc ccgaagcccg ggcccgaggc
    17581 gacgacgacc gcggtcaccg cctcgatcca gcggtcgtcc ggcagtccga tcaccgcggc
    17641 ctccacgacc cgcgggtgcg cgtacagcac ctcctccacc tcccgcgggg cgacctgcac
    17701 accaccggac ttgatcacat ccttgacccg gtcgacgacc gtgaaatagc cctgtgcgtc
    17761 ccgcaccccc agatccccga gcggaaccag ccgtcccgga aggccgcgca ggtctccccc
    17821 gggtccttcc agtacccctc gcacaactgc ggggaccggt agacgatctc accgggagtg
    17881 ccgtcgggga catccgcgcc ggtcacggtg tgggcgaccc gggcctccac gaagaggacc
    17941 ggccgtccgc acgactccat ccgccctcgt gctcctgcgg ccccagaacg gtcgccagcg
    18001 gcccgatctc gctctgcccg aagcagttgt acagggcgag gccgggcagc cgtgcgcgca
    18061 gccgctccag tacgggcacc ggcatggccg acgccccgta gtacgccttg cgcagcccgc
    18121 tcaggtcacg cccggcgaat ccggggtgcc ggcagagacc ggcccatacg gtcggcgggg
    18181 cgaagaggct gtcgcaccgg cccgcctcca ccagttcgaa gatccggtac gggccgggcg
    18241 cgtccaggat cgtgttccgc gcgccgaccg ccaggtaggg catcaggaag acgtgcaact
    18301 gcgcggagtg gtacagcggc agggcgtgga ccggccggtc gctctccttc aggtccaggg
    18361 cgggcacggc actggcgtac tcgtggacca gcgcgcggtg cgtcatcatc gcgcccttgg
    18421 gccgcgcggt cgtgccggag gtgtacagga gctgggcgag ttcccgttcg tccacctccc
    18481 cggcactcag catcgtcctg ccctccctgg gccaggcttc cacctggtcc agcagcgaac
    18541 cggtggcatc acgcagcggc atggaccgta cggaccgcgg caggtggtgg gcgagtgccg
    18601 gatcggtcag caccagcgcg ctgccggaat gctccaggat gtagcgcagt tccccgccgc
    18661 gcagttggtg gttgacgggt acgtgcacca gaccggcccg ggcgcacgcc aggaagccga
    18721 tcagatacgc gtcggagttg tgcccatagg cggcgacccg gtcaccgtcg gccagtccgc
    18781 cttccctcag gatcaccgac gcggccgtca ccgcctcgtc cagttcccgg taggtccagg
    18841 cccggtcgcc gtagcgcacg gccgtacgtc cggggacccg ccgggcgctg cgccgcagga
    18901 ccgcgtcgac cgtgccgctc cgcactcccg tcatgcggtg atcctcggcc cgtcccgcac
    18961 gcgggtcaag accaccggcc cattggtagg ctcaacgccc ccgtgcggca cgccagttgg
    19021 ccttcaccgg cccggtcgcc gccggtatac gacaggaacg ctgaacgctc gccagacacc
    19081 aggggaggat tcatgcgcaa ccgtctgaga aagctcgcac tcgccggggt ggtgctgctg
    19141 accgccgcgg ccccgctgcc gtcgggcgcg gcggcggccg aggcccgtac ccgtacgcac
    19201 ccgtccgccg acggcctgtc cgccgagatc cgctacaccg agtacgggat cccgcacatc
    19261 gtcgccgagg actacccgga cctcggcttc ggcgagggct gggcccaggc cgccgaccag
    19321 gtctgcaccc tggccgaggg cttcgtgacg ctgcgcggcg agcgctcccg gtacttcggc
    19381 gcgaccggtg ccgccgaccc cgccctgtcc tccgcgacca ccaatctcgc cggcgacctg
    19441 tacttcaagg gcgtacgcga gtccggcacc gtagagaaac tgctgcggca gcccgcgccc
    19501 gccgggccgg gacacgaggt ccaggagctg atgcgcggct gggtggccgg gtacaacgcc
    19561 tggctgcggc acaaccgcgt caccgatccc gcctgtgcgg gcaaggactg ggtacggccg
    19621 gtgacccggc tcgacgtggc gatgcgcggg tatgcgctcg cggttctcgg cggccagggc
    19681 cgtgcggtcg acggcatcac cgcggcccag ccgcccgccg gttccgccac ttccgggccc
    19741 gccacttccg ggcccaccac ctccgggcct gccgccccgg gccgtacgac cggaagccgc
    19801 gccgccgtcg ccgccgcccg cgcgctcttc cctcaggacg gcgcggacat gggctccaac
    19861 gcggtggcgt tccagggctc cacgacggcc gacggccgcg gtctgctcct gggcaatccc
    19921 cactacccct ggtccggtgg ccggcgcttc tggcagtcgc aggtcaccat ccccggcgag
    19981 ctgaacgcgg cgggcgcctc cctcctgggt tcctccacca tttccatcgg ccacaacgcc
    20041 cgtgtcgcat ggagccacac cgtggccacc ggcgtgccgt tcagcctcca ccggctcacc
    20101 ccggaccccg ccgacccgac cgcctacctc gtggacggca ggtccgagcc catgaagaag
    20161 cggaccgtca ccgtcccggt gcaggacggc accacggtca cccgtacgca gtggtggacg
    20221 cgttacgggc ccgtgctgac ctctctgggg cagctcaagc tgccctggag ccggtccgag
    20281 gtgtacgccg tcaacgaccc caacgcggtc aacatgcgct ccggtgacac ctccctggcc
    20341 ttcagcaagg ccgacggcgt ggccggcatc gagcgcgcgc tgcgccgtac gcaggggctg
    20401 ccgtggacga acaccgtggc cgccgacgcc gccgggcaca ccctctacac ccaggcgcag
    20461 gtgctgcccc ggggcaccga cgacctcgcg cggcgctgct ccacgccgct gggcgccgcc
    20521 acctacccgg ccacgggtct ggcggtcctg gacggctcac ggtccgactg cgccttcggc
    20581 agcgacccgg acgccgttca gccgggcatc ttcggcccgt ccgcggtgcc cacgctcaag
    20641 gacgccccgt atgccgagaa ctccaacgac agtgcctggc tgtccaacgc cgaccggccg
    20701 ctcaccggat acccgcgcat cttcggggac atcggtacgc cgcgctcgct gcgtacccgc
    20761 ggcgccttgg aagacgtctc ggcgatggcc gcccggggcc ggctcaccgt ggcggacctg
    20821 caacgacagc agttcgccaa ccgggcgccg gccggtggtc tggccgccgc ggacaccgcc
    20881 gccgcctgct ccgcactgcc cggcggcacc gcgccggaca gcggcggcag gccggtcgac
    20941 gtccgggaag cgtgtgaggt catcggccac tgggaccgga ccgtacgcac cgacagcgaa
    21001 ggcgccctgc tgttcgaccg gttctggcgg aaactgaccg ccaaggtgcc gccggccgag
    21061 cggtggaaga ccccgttcga cccggccgat cccgtacaca ccccacgcac cctgaacacc
    21121 gcggcccccg gcttcaccac cgccctcgcc gacgccgtgg ccgaactgtg cgccgcgggc
    21181 atcccgctcg acgctcccct gggagagcac cagttcgtcg tacggaacgg caagcggatc
    21241 cccgtccccg gcggcaccga ggcgctcggg atctggaaca agaccgaggg cctgtgggat
    21301 ccggcgggcg gtggataccg cgaggtggtc cacggctcca gctacatcca ggcggtcggg
    21361 ttcgacggca gccgctgccc ggtggcccgt acgctgctga cctactcgca gtcctccaac
    21421 ccgctctccc cgcactacag cgaccagacc gagctgtact cggccggccg tatgatccgc
    21481 gagcggttct gcgagaagga catcctggcc tcaccggagc tgagggtggt acgcgtccac
    21541 gacggccgct gagaccggcc cgtacgtcac catgccggcc ggtcgatcag gcggtcagcc
    21601 ggccggccgg tcggtcagtc ggtcaactcc acgtccgcac gtctacacgg cgcgctcccg
    21661 gccctcccag tacgggtcgc ggagccgccg cttgtagagc ttgccgttcg ggtcgcgcgg
    21721 catggcggcg gtgaactcca gcgtcctggg ccgtttgtac gccgcgagcc gctcggcgca
    21781 gtgcgcgagg atctcctcgg ccagcgcggg gcccggccgg tgcccgtcgg ccggctcgac
    21841 cacggccttg acctcctcac cccagtcctc gtgcgggaca ccgaaggccg cggcgtccgc
    21901 gaccgcggga tgggcgagga gggcggactc gatctcggcg gggtagatgt tgaccccgcc
    21961 cgagatgatc aggtcgatct tgcggtcgtg gaggaagaga tagccgtcct cgtcgaggtg
    22021 gccgaggtcg ccgacggtga agaagtcacc gatccggttc cggcgcgtct tgtcctcgtc
    22081 cttgtggtag ctgaatccgc cggtggtcat cttcatgtag accgtgcccg tctcgccggg
    22141 cggcagccgg ttgccgtcgt cgtcgaagac ggcgagttcg ctgatgggcc acgcctttcc
    22201 gacggtgccc ggcttcttga gccagtcctg cgcggtggcg aacgccccgc cgccctcact
    22261 ggccgcgtag tactcctcga cgcagttccc ccaccagtcg atcatcgccc gcttgacgtg
    22321 gtcggggcag ggcgcggcgc cgtggatggc gtgccgcatg gaggagacgt cgtacgccgt
    22381 ccggatctcc tgcggaaggg cgagcaggcg gtggaactgg gtcggcacca tgtgcgtatg
    22441 ggtgcagcgg taggtctcga tgaggcgcag catctcttgg ggcgtccact tgtccatcag
    22501 gaccagccgg tgccccatgt gcagggaggc cgccgcgaat tgcagcacgg cggtgtggta
    22561 gagcggcgag cagaccaggt gcacgttgcc gtcgaacggc ttgatgccga agatgcccag
    22621 gaagccgccg agcgcggtct cctcgggcgg cttgccgggc agcgggcggc ggatgccgcg
    22681 cgggcggccg gtggtgccgg aggtgtagtt catgacccag cccagggtgc ggccctcggg
    22741 tacggaaccc ggacggcccg ccaggagatc cgcgtacgga cggaatccgt cgaccgtgcc
    22801 gaccgcgtaa cgctgtccgg cgggcagccg cgcctggtcc gcggcggcgc gcacggcgcc
    22861 ggcgaaccgc tcgtgggcga tgagcgcctt ggccccgagt cgcggaggat ccaggcgatc
    22921 tccgggccta ccgagtggtg gttgacgggg acgaggtacc agccggcctg cgaggcggcg
    22981 aggtaggcgg tgagcatctc gacgccgttg ggcaggacga cggcgaaggc gtcgccgcgc
    23041 tccaggccgg ccgcgcgcag tccgtgcacc aggcggttgc aggcggcgtg cagccggtcc
    23101 gcggtccagc gctcgccgtc gggcgcgaaa aggaccgtac ggtcggggtc ggcggcggcc
    23161 tgggcccaga agccgttggg gggccgggac tcgtcggtca tggcactgtc ctcctcggga
    23221 gcggggcggt ggtcggtggg gtcgtgacgg tggcggggcc ggacgggcgc gcggtgagcg
    23281 gcgtacgggg cgcggcgtac ggcaccgcgc cgggcatgtc agccgcgggc accgcgccgg
    23341 gcatgtcagc cgcgcccggc gatgcggttg acgcggtcga cggcggcctc gaagccgcgg
    23401 gtcaggtcgt cgaagacctc ccgtacaccg cgctcggagt tcatccggcc gacgatctgg
    23461 ccgaccggcg tacccagcag cggctcgacc tcgtacttct ggatgcggga gagggcgtcg
    23521 gcgaccagca gcccctggag cggcatgggc agcgggccgg ggccggccgg gtcgtcccag
    23581 gcgtcggtcc acgcggtgcg caactggcgg gcgggcttgc cgctcagcgc gcgcgagcgg
    23641 acggtgtcgc ccggccccgc cgccaggagt ttgcgggtca gggcacggga gtgcagcgag
    23701 gcttcggtgg tggtcagcca gatggagccg agccagacac cctgcgcgcc cagggccagc
    23761 ccggcggcga tctgttcccc ggtgccgatg ccgccggcgg ccaggacggg cagcgggtgc
    23821 acggcccgta cgacttccgg ggtcagcacc atcgtggcga tctcgccggt gtggccgccg
    23881 gcctcgtagc cctgggcgac gacgatgtcg atcccggcgt ccttgtggcg ccgggcgtgg
    23941 tgcgggctgc cggccagcgc ggcgaggagg acgccacggt cgtgggcccg tcgtacgaca
    24001 tcggcgggcg gcgggccgag cgcgctggcc agcagcctga ccgggtggtc gaaggccacg
    24061 tccagttggc cgcgcgcgac ctgctccatc cagccggtga tacgccagcc ggacgcctcg
    24121 ccctcgcgca gcgggggaac gccgtaccgg gccaggacgt cctggacgaa acggcggtgc
    24181 tccggcggga tcatcgcctc gacgtcggct tccgtgacgc cctccacctt cttggcgggc
    24241 atgacgacgt cgagtccgta cggcagtccg tcggtgtgcc gggtcatcca ctccaggtcc
    24301 cgggcgagat cgtccggggc ggtgtagcgg acggcgccca ggacgcccag gccgccggcc
    24361 cgggtgatcg cggcggccac ggcggggaac ggcgtgaacc cgaagacggc gtgctcgatg
    24421 cccagcgcgt tgctcagctc cgtctgcatg ggcgcaggat gccgcagcgg gccgtacgag
    24481 ggaagacttc tctgacgtac cgtcagttgt gcggtgtgcg tccgcacgtc tcccgcacac
    24541 ccgccatgtc acttcttcac cggtcccgtc cgtccaccag gaaaacggcc ggaacctcca
    24601 acggaaggca tgagatgcga gacgagatca cggtgatcgg cggcggaacg gccgggctgg
    24661 tggccgccat cgcctgcgcg gaggcagggg cgcgggtgac gctccacgag gcgcacgcga
    24721 ccctgggcgg acgggcccgg gccacggccg caccccacgt cgcccacgaa ggcccccatg
    24781 tcttctacgc cgacgggccg cactggtcct ggctggccga ccgcggcctg accgggcgcc
    24841 tgtgccggcc gccggtccgg gacgcgctgc ggttctcctt cgtacgcggc gggcgcctca
    24901 ccccgcgccc gccggccggg ctcgtgcgga tgatggccgc cggcctcttc cgcgaagccc
    24961 cggtcgagga ggacttccac acgtgggcga cgcggcactt cggggagccg gcggcgcggg
    25021 ccgccgccaa cgccatcgcc gtggtgacgt acgacgcgga caccgggcgg ctgtcggcgg
    25081 ccttcgtatg gaggctgttc cgccgggtct tcgcgcccag gccgccggcg gtgcggtggg
    25141 tggcgggcgg ctggcaggcg gtcatcggcc gactggagat ccgcgcccgg cagctcggcg
    25201 tacgtgtcga accgagctcc cggatcaccg agttgcccgg ccatccgacg atcgtggcca
    25261 ccgaactctc cgccgcccgg gctctgttgg gcgatgagtc gctgcgctgg gagagcggcc
    25321 actgcgtcct gctggacctg gcggtgacca cggacccggc agccaggggc gcagcagtca
    25381 agggctcggc ggccaagagc ttggggatca agggtctggg gaccaagggc ttgcggctca
    25441 agaacccggc acccaggagt ccgcgtgacc gcttcatcgc cttcgacctg gacacgggcg
    25501 gcttccatga gagctactcg atgcaggacc cgagcaccgc gccgcccggg gagtcgctgt
    25561 tccagctcga catgccggta cgggccgggg agtccacggc acaggcccgg cggcggctgg
    25621 aggcgctggc cgatctcacc gtccccggct ggcgggagcg ggtgacctgg cagcgcggcg
    25681 gcacggcccg cggccggacc ggtgcgctcg acctgcccg
//
