LOCUS       NZ_CP074380            21137 bp    DNA     linear   CON 27-MAY-2024
DEFINITION  Streptomyces sp. MST-110588 chromosome, complete genome.
ACCESSION   NZ_CP074380
VERSION     NZ_CP074380.1
KEYWORDS    RefSeq.
SOURCE      Streptomyces sp. MST-110588
  ORGANISM  Streptomyces sp. MST-110588
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1  (bases 1 to 7915503)
  AUTHORS   Booth,T.J., Bozhueyuek,K.A.J., Liston,J.D., Lacey,E. and
            Wilkinson,B.
  TITLE     Bifurcation drives the evolution of assembly-line biosynthesis
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 7915503)
  AUTHORS   Booth,T.J., Bozhueyuek,K.A.J., Liston,J.D., Lacey,E. and
            Wilkinson,B.
  TITLE     Direct Submission
  JOURNAL   Submitted (10-MAY-2021) Molecular Microbiology, John Innes Centre,
            John Innes Centre, Norwich, Not US or Canada NR4, United Kingdom
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: 28-FEB-2016
            Assembly Method                   :: HGAP v. 3.0
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 25.0x
            Sequencing Technology             :: PacBio RSII
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_022695595.1-RS_2024_05_27
            Annotation Date                   :: 05/27/2024 05:38:09
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 6,918
            CDSs (total)                      :: 6,828
            Genes (coding)                    :: 6,327
            CDSs (with protein)               :: 6,327
            Genes (RNA)                       :: 90
            rRNAs                             :: 7, 7, 7 (5S, 16S, 23S)
            complete rRNAs                    :: 7, 7, 7 (5S, 16S, 23S)
            tRNAs                             :: 66
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 501
            CDSs (without protein)            :: 501
            Pseudo Genes (ambiguous residues) :: 0 of 501
            Pseudo Genes (frameshifted)       :: 350 of 501
            Pseudo Genes (incomplete)         :: 185 of 501
            Pseudo Genes (internal stop)      :: 14 of 501
            Pseudo Genes (multiple problems)  :: 45 of 501
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 12:56:23
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 178046
            Orig. end                         :: 199183
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP074380.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            Bacteria and source DNA available from Barrie Wilkinson, John Innes
            Centre, Norwich.
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..21137
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene-precursor"
                     /region_number="3"
                     /rules="(PT_FPPS_like and not PT_HPP)"
                     /tool="antismash"
     cand_cluster    1..21137
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_FPPS_like and not PT_HPP)"
                     /kind="single"
                     /product="terpene-precursor"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..21137
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:11137](+)"
                     /cutoff="10000"
                     /detection_rule="(PT_FPPS_like and not PT_HPP)"
                     /neighbourhood="10000"
                     /product="terpene-precursor"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..11137
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="(PT_FPPS_like and not PT_HPP)"
                     /neighbourhood="10000"
                     /product="terpene-precursor"
                     /protocluster_number="1"
     gene            complement(503..736)
                     /locus_tag="KGS77_RS00895"
     CDS             complement(503..736)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="KGS77_RS00895"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_242578094.1"
                     /transl_table=11
                     /translation="MQRPVLRRGRGHLHTHTLTWFRHSTDHGPVYFHGGATPGQEAFLG
                     FRPATRTALAAFATRRYRRGSSLARAAYELLV"
     gene            complement(<990..1619)
                     /locus_tag="KGS77_RS00900"
                     /pseudo=""
     CDS             complement(<990..1619)
                     /GO_function="GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1053: beta-lactamase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF012371.4"
                     /locus_tag="KGS77_RS00900"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /product="serine hydrolase domain-containing protein"
                     /pseudo=""
                     /transl_table=11
                     /translation="MTDAYIGPRQLRATAERFEAPDVVLALSQDGRRTVVSAGTATYGY
                     GAPAREALRYELGSASKTFTGLLLARLAEDGVLSPGDPVTRHLPVSPAPHVHRDAITPF
                     HLITHTSGLPRLPRDIYRRALPHWRTNPYVHYAPGQLLDAFARSRPRHAPGTHWHYSNF
                     GVALLAPALAHAAAAPFDRLLSAHVLTPLGLADTGLGPQGAGLDGTG"
     gene            complement(1616..2497)
                     /locus_tag="KGS77_RS00905"
                     /old_locus_tag="KGS77_00895"
     CDS             complement(1616..2497)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007502138.1"
                     /locus_tag="KGS77_RS00905"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KGS77_00895"
                     /product="hypothetical protein"
                     /protein_id="WP_242587232.1"
                     /transl_table=11
                     /translation="MNWLEAHREHFRLRLNRDTPARQVKERLKPVGELALVGRILTREG
                     VTGSRQAAQIRRLLDFAWQDVLEGGEVLAWMQRDEPLSPVPLELYVPFRELGYSHPGVA
                     EHARLVSRTTSWRALEAPPSRRLGIARFAARAGLPAGIDEPAAVRRTWLGHTPEPWTVD
                     HHIAYAVTHTVFHLTDWGERLGNLPEDIARYLTLWLPVWTEEWALHRHWDLLGELLVVD
                     ACLPRPALDTGIWQRYADAQSPEGAMPVQHTMPTGDAGEIFDLVHHPTLVAVFASTMAV
                     SRAMTALSDSAP"
     gene            complement(2400..3341)
                     /locus_tag="KGS77_RS00910"
     CDS             complement(2400..3341)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="KGS77_RS00910"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_242578095.1"
                     /transl_table=11
                     /translation="MYAAFAEAGLRHDRFETFLRATVTTRAWRLTEREPTRTLAVLLAE
                     RRLALPPHCDREAAQARTWLGGLAEPWAFTTSAGYAATHHVFHLTNWGAEPRALAAAVR
                     DHLALWLPAWLDCTVAAGHWDLTGELLAVAAMLPVPPASPAPYVLPGVAQAWRALAAAQ
                     RPDGAVPEVAEIKGTVDSPETVYVPETVDAPEPDEAEHTFRTCYHSTLVTAFAATLAAH
                     MARRTSDDDPVPPRPRARARHRRHPHPHLRHPRPTSARTPPGKDRDDHSPTAAPGRCRC
                     AELAGGPPRALPSAPEPGHPGPSGQGTPQARR"
     gene            complement(3820..4428)
                     /locus_tag="KGS77_RS00915"
                     /old_locus_tag="KGS77_00900"
     CDS             complement(3820..4428)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007455150.1"
                     /locus_tag="KGS77_RS00915"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KGS77_00900"
                     /product="hypothetical protein"
                     /protein_id="WP_242578097.1"
                     /transl_table=11
                     /translation="MVTRSDDPLAPAAARVLGADVLAPCTLLGQTASEADIALLGTAAR
                     AFPPAAGSSSSEWNHWGLLGALRLTGATAGTAAGTGAEPAASWVTADPWPRVTHRLAQV
                     AALAGLPLPSELSAAAGGRVVDVARGFVRAVRRRDWFQAAGAGRWLATMDDVPPSLGLD
                     RGLAFVAQMGGDDARVALHVQVAQALLVGTAGATRPAVR"
     misc_feature    complement(4495..4509)
                     /note="TFBS match to IolR, Regulator of the inositol
                     catabolism, confidence: medium, score: 18.34"
                     /tool="antismash"
     gene            complement(4599..4787)
                     /locus_tag="KGS77_RS00920"
     CDS             complement(4599..4787)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003987799.1"
                     /locus_tag="KGS77_RS00920"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="hypothetical protein"
                     /protein_id="WP_242578099.1"
                     /transl_table=11
                     /translation="MLPVETPSTTSARTEKLAEDVEGLLNPVEADGSFHDSAECLVLLI
                     GGAGFLLSPPAPRPTKR"
     gene            complement(5015..5907)
                     /locus_tag="KGS77_RS00925"
                     /old_locus_tag="KGS77_00905"
                     /pseudo=""
     CDS             complement(5015..5907)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_function="GO:0016987 - sigma factor activity [Evidence
                     IEA]"
                     /GO_process="GO:0006352 - DNA-templated transcription
                     initiation [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004938421.1"
                     /locus_tag="KGS77_RS00925"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /old_locus_tag="KGS77_00905"
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /pseudo=""
                     /transl_table=11
                     /translation="MYGAGETGFLAERFEEHRTHLRAVAYRMLGSLSEADDAVQETWIK
                     LSRADTGAVGNLGGWLTTVVGRVCLDMLRARTARREEPMEDQVRLPDPLVSGVHGIDPE
                     QQALLADSVGLALLVVLETLAPAERLAFVLHDLFAVPFDEIGPIVGRTPTAARQLASRA
                     RRRVQGAAPAPDTDLARQREVVDAFLTAARGGDFEALVAVLDPDVVARSDSGTERPGAV
                     LRGAAAVAGRAMTFARFAEAARPRWSTGPRASWRCRRDGRCRSWRSRSRKARSWPWTSS
                     PTPNASPGSTSRSSTA"
     gene            6320..7180
                     /locus_tag="KGS77_RS00930"
                     /old_locus_tag="KGS77_00910"
     CDS             6320..7180
                     /EC_number="1.1.-.-"
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /NRPS_PKS="Domain: PKS_KR (6-161). E-value: 8.9e-11. Score:
                     34.0. Matches aSDomain:
                     nrpspksdomains_KGS77_RS00930_PKS_KR.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) adh_short"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1001: short-chain dehydrogenase/reductase SDR"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF012334.4"
                     /locus_tag="KGS77_RS00930"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KGS77_00910"
                     /product="SDR family oxidoreductase"
                     /protein_id="WP_242578102.1"
                     /sec_met_domain="adh_short (E-value: 7.6e-32, bitscore:
                     109.4, seeds: 230, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTQERPVVVTGCSSGIGRAVVRHLLGREHTVYATARDIGSIGDLA
                     SDGARILPVDLTDAGAMRECVRHVEARHGAVWGLVNNAGYALTGPVEELDMDQVRQQFE
                     VNVFGHITMTQLVLPGMRRRGEGRIVNISSVASRFTLPGGGCYHASKHALASFGDALRY
                     EVSPFGVRVSAIEPAVVRTRFIVTAVRLLTARGPGTGAYASFRDALADCYARVQRTPYR
                     YGAVSADKVARAVGRVLASDSPGPRHVVGAAARLTVGLRWLLPGPLFDAVVRARFPVPR
                     QEGRS"
     aSDomain        6338..6802
                     /aSDomain="PKS_KR"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_KGS77_RS00930_PKS_KR.1"
                     /evalue="8.90E-11"
                     /label="KGS77_RS00930_PKS_KR.1"
                     /locus_tag="KGS77_RS00930"
                     /protein_end="161"
                     /protein_start="6"
                     /score="34.0"
                     /specificity="KR activity: inactive"
                     /specificity="KR stereochemistry: C2"
                     /tool="antismash"
                     /translation="VVVTGCSSGIGRAVVRHLLGREHTVYATARDIGSIGDLASDGARI
                     LPVDLTDAGAMRECVRHVEARHGAVWGLVNNAGYALTGPVEELDMDQVRQQFEVNVFGH
                     ITMTQLVLPGMRRRGEGRIVNISSVASRFTLPGGGCYHASKHALASFGDAL"
     CDS_motif       6341..6397
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_KGS77_RS00930_0001"
                     /evalue="1.60E-04"
                     /label="PKSI-KR_m1"
                     /locus_tag="KGS77_RS00930"
                     /protein_end="26"
                     /protein_start="7"
                     /score="14.3"
                     /tool="antismash"
                     /translation="VVTGCSSGIGRAVVRHLLG"
     gene            7177..8781
                     /locus_tag="KGS77_RS00935"
                     /old_locus_tag="KGS77_00915"
     CDS             7177..8781
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1005: Drug
                     resistance transporter, EmrB/QacA"
                     /gene_kind="transport"
                     /inference="COORDINATES: protein motif:HMM:NF019310.4"
                     /locus_tag="KGS77_RS00935"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KGS77_00915"
                     /product="MFS transporter"
                     /protein_id="WP_242578104.1"
                     /transl_table=11
                     /translation="MTRQWGVLGVLCLALLLLGVDQTVLNVALPQMQRDLHLGSAQLQW
                     VVGAHMLALAAGVLAAGNWGDRRGRRRALVAGLVICGLASVLGALADSAAEIIAARAVM
                     GLGAAFIMPSTLSVLVQVFPQPARQRLAITIWSTVAGVGVLLGPVSGGWLLEHCSWRAC
                     FWGTLPLVVLPLCCVPVLVPPCRDDQAPPPDPAGLLLSGAGLFAVIWSFIQAPVLGWTD
                     PLVVGVAALGATLLAAMICWERRAPAPMLPLGFFRDRGYAVAATMLCLMFFTLVGATFL
                     LTFYLQGLKAMSPLAAGRTLLAGGLAVAVGGLVSAVLARRTRARTVMAVGMLLNVCAFV
                     VLAGTTAGSSLSRLYVFLSLIGLGVGLAGGPATSLIMRAVPQRRAGIGAGVNDAVRSVG
                     STSGVAVVGSVFNTVYSSRIARSPGAPVPAGARDHLLGALAQAERLVSRASTGRGRLQP
                     SERLRLLGAARHLAEDAAQAFTAALRTTSWLSAGICCAGCAWYSARCPAAGRRHHHRRH
                     RPRHRQRPRCPPSSRTG"
     gene            8786..9805
                     /locus_tag="KGS77_RS00940"
                     /old_locus_tag="KGS77_00920"
     CDS             8786..9805
                     /GO_function="GO:0016301 - kinase activity [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF012981.4"
                     /locus_tag="KGS77_RS00940"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KGS77_00920"
                     /product="diacylglycerol kinase family protein"
                     /protein_id="WP_242578106.1"
                     /transl_table=11
                     /translation="MRGTLIVNPASTGAGDAVLRAVLAELTPVVRLDVAVTACPGHAFH
                     LARAARRDGVRLVAVLGGDGTVNEAVNGLLADGWDAGPHHRPAVPALGILPAGGLNVAA
                     RALGLGRHAVPAARRLAEAVGQGRRTVVNLGKADHRYFLTAAGVGFGAELMALVQQGRQ
                     ENRCPPGRRQSRWRQRGRGGGRSGAWSRYLMPAARHFLSGTDRRVPALSVALPQEEPQQ
                     RAERTEGVFALLVANTSPYAYMGRWPLAPCPAASFQDDLEALAFTDLSTHRCAALLARM
                     LLRPRHEHNGRPVRRFAGRQSLSVTVTRPVAVHVDGEVLTPRREVRFSSTRGALAVAL"
     misc_feature    9854..9867
                     /note="TFBS match to PsrA, Oleic acid responsive regulator,
                     confidence: weak, score: 18.1"
                     /tool="antismash"
     gene            10001..11137
                     /locus_tag="KGS77_RS00945"
                     /old_locus_tag="KGS77_00925"
     CDS             10001..11137
                     /GO_process="GO:0008299 - isoprenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene-precursor: PT_FPPS_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1182: Polyprenyl synthetase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF012568.4"
                     /locus_tag="KGS77_RS00945"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KGS77_00925"
                     /product="polyprenyl synthetase family protein"
                     /protein_id="WP_242578108.1"
                     /sec_met_domain="PT_FPPS_like (E-value: 7.3e-47, bitscore:
                     158.4, seeds: 145, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MELPGALRRDMRRFAAQLSAHINALYPDTNALNLDVTRELLGLSP
                     DQELPPALAGHVQDRVHRTLVRPVRHLVDAGGQRWRPYLLAKIIHVLGGDSVFYTPLLA
                     AGELMHTGSLIIDDVQDEAPVRRGRAAAHTVYGTPTALNAGTAAFFAFDRALRRVVPDD
                     VVLRCAVQDAYLSALRAAHAGQALDILGLREEMDTAVATGNAGPLLDQVRLTHRLKSGA
                     PVRAAFHVGALLVGSSAELSGALQRFGEAVGTAYQITDDVLDLRGVVRAGAPTKSVAED
                     LRNGKVTMPLAHAVALLPRRDVEAVWHLVRDGHLSEDGVREAIGALETCGAVDACVDEA
                     ERMLLAAWEQVKPLLPGTRQSCFIHALARHTVRRVRVA"
     gene            complement(11275..11859)
                     /locus_tag="KGS77_RS00950"
                     /old_locus_tag="KGS77_00930"
     CDS             complement(11275..11859)
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF021509.4"
                     /locus_tag="KGS77_RS00950"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KGS77_00930"
                     /product="oxygenase MpaB family protein"
                     /protein_id="WP_347404569.1"
                     /transl_table=11
                     /translation="MRLPGGRTALRTINRAHRWYAISNEDMLYTLSAFVHEPIRWIDAY
                     GWRPLLEQEKLAAFWFYRNVGERMNIQGIPSDYTQFEEFNREYERSRFATAPSGRRVAD
                     QALGVVGRWFPAPVRPVVRRVVVGLMDPPLRTAFGYREPRLLPYLVRGTLRARARVQRL
                     GPARRRSYYDDPPKVRSYPGTQGDYGIADFG"
     gene            12270..13688
                     /locus_tag="KGS77_RS00955"
                     /old_locus_tag="KGS77_00935"
     CDS             12270..13688
                     /EC_number="1.2.1.79"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Aldedh"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1017: aldehyde dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF006916.0"
                     /locus_tag="KGS77_RS00955"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KGS77_00935"
                     /product="succinic semialdehyde dehydrogenase"
                     /protein_id="WP_347404413.1"
                     /sec_met_domain="Aldedh (E-value: 3.8e-117, bitscore:
                     390.3, seeds: 89, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAAGRETTSPPAADPTATPTRAIPLAGRTGLPLGRAVVDTGTDTH
                     SGAGTGTGTGSGAAGYTLSIAPFTGAPLGRVPHCGPRDLDRVFSRARTVQRAWAETGVR
                     GRAAVLLRFHDLLLRHRDDLLDLIQYEAGKARAHALEEVIDCALTTRHYARRAPALLRP
                     RRRRGALPLLTHVVEHRRPRGVVGVLAPWNYPLTFAVCDTVPALLAGNAVVCKPDVQGA
                     FTALRVRDLLHEAGLPHGLHQVVTGPGDEVGPAVVARSDHVTFTGSTTTGRSVAALAGE
                     HLIDCTLELGGKNAFIVLDDADLDTAVRGAVRACFTGAGQLCMSAERVLVHADRSADFL
                     RAFAAATRALRLGAAFDYRADIGSLASAARLRTVDEHVRDATGKGASLVTGGRPRPDVG
                     PFFYEPTILTGVTDAMSMYGQEVFGPVAAVASFRDEQDAVEQANAGRFGLNASIWTSRP
                     AAHGPWPPASGPVR"
     gene            13691..13924
                     /locus_tag="KGS77_RS34800"
                     /old_locus_tag="KGS77_00940"
     CDS             13691..13924
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Aldedh"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF012398.4"
                     /locus_tag="KGS77_RS34800"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KGS77_00940"
                     /product="aldehyde dehydrogenase family protein"
                     /protein_id="WP_347404414.1"
                     /sec_met_domain="Aldedh (E-value: 5.2e-06, bitscore: 23.9,
                     seeds: 89, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNEPYAAAYASVDAPMGGMKDSGVGRRHGRDGLLSYTEAQTVATQ
                     RLLPLTPPDTLSGQSYATFVTRLLLLAKHLRA"
     gene            complement(13983..14186)
                     /locus_tag="KGS77_RS00960"
                     /old_locus_tag="KGS77_00945"
     CDS             complement(13983..14186)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="KGS77_RS00960"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="KGS77_00945"
                     /product="hypothetical protein"
                     /protein_id="WP_242578111.1"
                     /transl_table=11
                     /translation="MTFGWLRWLRYADDFGYSHGLLPGTVGTVAVLGTAFVAGYLLRRV
                     AVASWAVPLVLTGAGIAWLATH"
     misc_feature    14177..14191
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: weak, score: 19.35"
                     /tool="antismash"
     gene            complement(14362..15405)
                     /locus_tag="KGS77_RS00965"
                     /old_locus_tag="KGS77_00950"
     CDS             complement(14362..15405)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010636628.1"
                     /locus_tag="KGS77_RS00965"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KGS77_00950"
                     /product="hypothetical protein"
                     /protein_id="WP_242578125.1"
                     /transl_table=11
                     /translation="MRAKGICYDTGFLRKGTNSRERFDPDLVTRELAVIRDDLHCNAVH
                     ITGGDPERLEFAARCAADLGLEVWFSPYPLELTTDEILTLLADCAARAERLRTRGAEVV
                     FVAGVELSVMNQGFLEGDSTEERLGRLLGDPARRPEKFAAVAARLNAFFREAVPMVRER
                     FHGKVTYAVIQFEGVDWDVFDFMTYELIRSAEVADRFREGVRSLVAQPEAAQPKPVAIT
                     GFGTATWRGAGDMAPRSMGILEYDEATGAPLRLSGKYERDEAGQAAYVRELLEIFDSEG
                     VDSAFVFLFAVHNLPHRPDGDARDDLDLASLGVVKVLEDRHGDTYPDLPWEPKAAFAAV
                     ADHYRGG"
     misc_feature    complement(15148..15150)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            complement(15585..16508)
                     /locus_tag="KGS77_RS00970"
                     /old_locus_tag="KGS77_00955"
     CDS             complement(15585..16508)
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1199: NmrA family
                     protein"
                     /gene_kind="other"
                     /inference="COORDINATES: protein motif:HMM:NF017206.4"
                     /locus_tag="KGS77_RS00970"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KGS77_00955"
                     /product="NAD(P)H-binding protein"
                     /protein_id="WP_242578127.1"
                     /transl_table=11
                     /translation="MTILITTPNGGVGRHLTEALRGREDVRFLVRSEAGARALGEVRGE
                     VFRGDAADADDVRRAVAGVERLYLAHPFSVDQIAVETGLGLAALEAGVRRIVKLGARAF
                     TGAGTVPDAVTGNHDVIAGRLRGAGVPELTVLRPDRFLQNFLTAAAAIAGGTLADPAGP
                     AGARGYVDVRDIAEVALAELLADRPVGGDIEISGPHALTLPELAIRFGAALGRRVRYVD
                     VPLDDAWREDLARRGVPAPVVDGLRDLYTNYRREGVAGLGTASGVCSAARRARRRTSRP
                     TSSHPPPPCRKTVPALIWSSVNRRAI"
     misc_feature    complement(16493..16507)
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: weak, score: 17.98"
                     /tool="antismash"
     misc_feature    complement(16494..16509)
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: weak, score: 18.09"
                     /tool="antismash"
     gene            complement(16720..17874)
                     /locus_tag="KGS77_RS00975"
                     /old_locus_tag="KGS77_00960"
     CDS             complement(16720..17874)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006380309.1"
                     /locus_tag="KGS77_RS00975"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KGS77_00960"
                     /product="XdhC/CoxI family protein"
                     /protein_id="WP_242578130.1"
                     /transl_table=11
                     /translation="MKEILDDLDRWRAEGRRVAVARVVEVSGSGPRQPGAAMAVTEDGE
                     VAGSVSGGCVEGAVVAEALDVLARGGHRLVTFGYSDEDAFAVGLTCGGTVRLFIEELDA
                     THLLVADAVRAERPFALVTVIDGPGTGAKALVRPDGPPAPGDFGVRAALRDAGEAIADG
                     VNALRTYTGTTDSTNAINATNPTDTLGATTGSVAPSVTTTVFIDTYTPPPRMIILGAVD
                     FSAALARAAKLLGYRVTVCDARATFATHRRFPMADEIVVDWPHRYLDRVGTGLGPRDAV
                     CVLTHDAKFDVPAVLSALRTDVGYLGAMGSRRTHEDRRDRLRAAGAGADELQRLMSPIG
                     LAIGARTPEETAVAICAEIIALRGVRGATVASLRDTQGPVHPRL"
     gene            complement(17871..20066)
                     /locus_tag="KGS77_RS00980"
                     /old_locus_tag="KGS77_00965"
     CDS             complement(17871..20066)
                     /GO_function="GO:0043546 - molybdopterin cofactor binding
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1293: aldehyde oxidase and xanthine dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF042649.2"
                     /locus_tag="KGS77_RS00980"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KGS77_00965"
                     /product="xanthine dehydrogenase family protein
                     molybdopterin-binding subunit"
                     /protein_id="WP_242578134.1"
                     /transl_table=11
                     /translation="MKTNGKTGPAPQGVRRPDDPAPQGPHRPGGSAPQGLRRPDGPAKL
                     TGAALYTADRPHPDALVAALVTATVPTGRLAALDTAAAERAPGVVRVIRHQDMPRLNPM
                     PSPPMGHTVLVMQDDRIHYEGQPVAVVLARTWEQARYAASLVDASYEDVVEPVMFGAAP
                     EIEARGPMLLREEPDVGVGDVEAGLARADVVVDATYTTSDRHANAIEPPAVLAWWEEDR
                     LTLHVSTQAVALTQGTVAALFGVAPQNVTVHSPYVGGGFGSKAFLQQPVPLAVAAARVA
                     GRPVRLVLTRAQTFTLCGHQAATRQRVRIGARRDGRLTALEHRSTNATTRAADYHIEAA
                     TAGSGSLYASPAIALKARVEQVDRPAPTPMRSPNEGVGLFALESAMDELSYELGMDPVE
                     LRIRNEPTVHPMTGRPFSSRRLVECLREGARRFGWDGRPPAGSLREGDDLIGWGVATAV
                     MDSFRGPAAARIRAGAGGRIVVETGTEEIGTGIPAMVQAVASQALGIGPADIEVRHGSS
                     DLPAHGGVFGSMTTMSVGSAVHVAATALREKLTAAGGFEGMRQAGIDTLEAEGNWAPEA
                     SAHPNGTASEVSALVYGAFFAEVRVDADLGLVRMTRGVGVYSAGRIINPLAARSQLTGG
                     IIWGLGQALRERSVMEPGRGRFLHKNLAGYVVPVHADIGDLDVSFIEDEDRHASAIGAK
                     GIGEIGSNGTAAAIANAVHHATGRRIRSLPITAEDLL"
     gene            complement(20063..21049)
                     /locus_tag="KGS77_RS00985"
                     /old_locus_tag="KGS77_00970"
     CDS             complement(20063..21049)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016470637.1"
                     /locus_tag="KGS77_RS00985"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KGS77_00970"
                     /product="xanthine dehydrogenase family protein subunit M"
                     /protein_id="WP_242578135.1"
                     /transl_table=11
                     /translation="MKTFTYERATTLQQALTARTEPGTQLLAGGTELLNWLKEGIERPE
                     RVVDINGLPLDGIDVDDDGLRLGALARMSDVHAHPEVARRYPAITESLLRSASAQLRNM
                     ASIGGNLLQRTRCPYFRADTALPCNKREPGSGCAALAGGDTGAHALFGWSPACAATHPS
                     DLAVALAALDAVVVTESGRRGRRRIPVTEFHRLPQDRPELHTRLRPDELVTGVEVPPDH
                     GTSWYLKVRERASYEFALVSVAVSVEVEGEVINRARLALGSVAPRPWRLWAAEDALVGV
                     ALSDVDGLRSAVAASFEDALPLPDNAYKIELAQRAAVRALRVAGGAA"
ORIGIN
        1 cgtgcccgcc tggacggcac ggactcctac aacgtcgtcg cggtgaccga cgggaagccc
       61 gtcggcatgg ccagtggcgt tctcggcacg catcacggcg ttgtggagct gatctccctg
      121 tgggtcgacg gtgctgcccg ggggcgggcg tcggggaccg tctggtgcgg gcggtggagc
      181 agtgggccgt acgccggcgg gcggacgcgc tgcggctcgc ggtcgggccc ggcaacgcgt
      241 acgcgatcgc gctgtaccgg cggcacggat tcgagatggc cgggcaaacc gggggcgcgt
      301 cgcccggcgg gggacggcaa cgggaacatg tgatggcgaa gtcgctgcga gacgctgtcg
      361 gtacgagggg cgagggctga ttcaggctgc cgagttgcct gctggggcgt tgtgtccgag
      421 tggtgtgtcc gagtggtgtg tccgggtggt gtgtccgagt cgctcgggag cggtcgcggt
      481 ccggcccgac cctctgcctc ggtcacacga gcagttcgta cgcggcccgt gccaggctgc
      541 tgccgcgccg gtagcggcgg gtggcgaagg cggcgagggc ggtacgggtg gccgggcgga
      601 agcccaggaa ggcttcctgg ccaggggtgg cgccgccgtg gaagtagacc gggccgtggt
      661 cggtggagtg acggaaccag gtgagggtgt gggtgtggag atgcccacgg ccgcgccgga
      721 gcacgggccg ctgcaccgcg cggagcgcct ggcccagagc acgggggtcc gacggggccg
      781 gaggtgagcc tccaggtaag tgagcaggtc atcgggtgtg ccgcggatgg ctcccgccgc
      841 ggcgaaggcc gcggcgtcga agggcggaag cgccttgcgc ccgagactgt cgtgcccggt
      901 ggcgtcggtg accacggtga cgagccgggt cggggtgacg ggcccggtcg cggcggcggc
      961 ccggtcgggg cgatctcggt ggggttctgc cccgtgccgt cgagcccggc gccctggggg
     1021 ccgagtccgg tgtcggccag gcccagtggt gtcaggacat gggcgctcag cagccggtcg
     1081 aaaggggcgg cagccgcgtg cgcgagggcg ggggccagga gcgccacacc gaagttggag
     1141 tagtgccagt gggtgcccgg ggcgtgacgc ggacggctgc gggcgaaggc gtcgaggagt
     1201 tggcccggcg cgtagtgcac atagggattg gtacgccaat ggggcagcgc ccggcggtag
     1261 atgtcacgcg gcaggcgcgg cagcccggac gtatgggtga tcaggtggaa gggggtgatg
     1321 gcgtcacggt gaacgtgtgg tgccgggctg acgggcagat gacgggtgac cgggtcgccc
     1381 gggctcagca caccgtcctc cgccaggcgg gccaggagca gcccggtgaa ggtctttgag
     1441 gcggagccca gttcgtagcg cagtgcctcg cgggcgggcg ctccgtaccc gtacgtggcg
     1501 gtgccggcgg agacgacggt gcgccggccg tcctgggaca gggccagcac cacgtcggga
     1561 gcctcgaagc gctcggcggt cgcgcgcagt tgacgggggc cgatgtacgc gtcggtcatg
     1621 gggcggagtc gctgagcgcg gtcatggccc gggagacggc catggtcgag gcgaagaccg
     1681 cgacgagtgt ggggtggtgt acgaggtcga agatctcgcc ggcgtccccg gtgggcatcg
     1741 tgtgctggac gggcatggct ccctccgggc tctgcgcgtc cgcgtaccgc tgccagatgc
     1801 cggtgtcgag cgcgggccgg ggcagacagg cgtcgacgac gaggagttcg ccgagcaggt
     1861 cccagtgccg gtgcagcgcc cactcctcgg tccatacggg cagccacagg gtgaggtagc
     1921 gggctatgtc ctcgggcagg ttccccagcc gttcccccca gtcggtgagg tggaagacgg
     1981 tgtgggtgac ggcgtacgcg atgtggtggt cgaccgtcca gggctcgggg gtgtggccga
     2041 gccaggtacg gcggaccgcc gccggctcgt cgatgccggc cggcaggccc gcgcgggcgg
     2101 cgaaacgggc gattcccagc cgccggctgg gcggggcctc cagcgcccgc caactggtcg
     2161 tacggctgac caggcgggcg tgttctgcca ccccggggtg gctgtatccc agctcgcgga
     2221 agggcacgta cagctccagc ggcaccggtg agaggggctc gtcccgctgc atccaggcca
     2281 ggacctcgcc gccttcgagg acgtcctgcc aggcgaagtc cagcagccgc cggatctgtg
     2341 cggcctggcg cgatccggtg acgccctcgc gggtcaggat gcggccgacc agtgccagtt
     2401 caccgacggg cttgaggcgt tccttgacct gacgggccgg ggtgtcccgg ttcaggcgca
     2461 gacggaagtg ctcgcggtgg gcctccagcc agttcagcgc accggcaccg acctggtgca
     2521 gcagtggggc tgtggtcatc gcggtccttt cctggcgggg tcctggccga ggtggggcgg
     2581 gggtgacgga ggtgcgggtg agggtgacgg cggtgccggg ctcgggcccg gggtctgggc
     2641 gggaccgggt cgtcgtcgga ggtacggcgt gccatatgag ccgcgagtgt ggcggcgaag
     2701 gccgtgacga gggtggagtg gtagcaggta cggaaggtgt gctcggcctc gtcgggctcc
     2761 ggggcgtcca cggtttccgg aacgtacacg gtctccgggg agtccacggt tcccttgatc
     2821 tccgcgacct ccgggacagc gccgtcgggc cgctgcgccg ccgccagcgc ccgccacgcc
     2881 tgggcgactc ccggcaggac gtacggagcc ggcgaggcgg gcgggaccgg gagcatggcc
     2941 gcgacggcga gcagctcacc ggtcaggtcc cagtggcccg ccgctaccgt gcagtccagc
     3001 caggccggca gccacagggc gaggtggtcg cgtacggcgg cggccagcgc ccgcggttcc
     3061 gcgccccagt tggtgaggtg gaagacgtgg tgcgtggcgg cgtagccggc ggatgtggtg
     3121 aatgcccacg gttcggccag cccgcccagc caggtccgtg cctgggccgc ttcgcggtcg
     3181 cagtgcggcg ggagtgcgag cctgcgctcg gcgaggagta cggccagtgt gcgcgtcggt
     3241 tcgcgttcgg tcagacgcca ggcccgggtg gtgacggttg cgcgcaggaa cgtttcgaaa
     3301 cggtcgtggc gcagccctgc ctcggcgaag gccgcgtaca tctccagcgg gtacgtcgca
     3361 tgcggctcgc gccgtgccag tgcggcgaag acctctcccg gccggtttcc cgccaggcga
     3421 aatccaggag cgcgcgggcc aggtcgccga ccccaccgac ctccccgaca ccggttacct
     3481 tgctggtccc gctggactcg ccggtccttc ccgtcccacc ggtcccgccg tccatcgcac
     3541 cggtcccgcc gtccgacgca ccggacccgc cgcccggggc caggtcgccg aggcgggcga
     3601 tggagtggct tacctgcgcc agctcgccca gggggcgcaa ggtcacgttc cggtcgtgct
     3661 gcgggccggt ggggtcgtcg ggaagccgga agccgtcccg gtgccggtac agccagccca
     3721 gggccgccgc cgcgatccgc tccggttggg cgcgtgggcc accgtccacc ggtccggctc
     3781 tgcgcccggt gaccggtccg gcggccggcc cggcggcggt caccggaccg ccggccgcgt
     3841 ggcccccgcc gtgcccacga gcagggcctg cgcgacctgg acgtggaggg ccaccctggc
     3901 gtcgtcgcct cccatctggg cgacgaaggc gaggccgcgg tccaggccca gcgagggcgg
     3961 aacgtcgtcc atcgtggcca gccagcgtcc ggcgccggcc gcctggaacc agtcgcggcg
     4021 gcgtacggcc cgtacgaagc cccgtgcgac gtccacgacc cgtccgcccg cggcagcact
     4081 cagctcggac ggcagcggca gccccgcgag cgcggccacc tgcgcgagcc gatgggtcac
     4141 ccgcggccag gggtccgcgg tgacccagga cgcggcgggc tcggcgccgg tcccggcagc
     4201 ggtgccggcc gtggcaccgg tcaggcgcag cgcgcccagc agcccccagt ggttccactc
     4261 gctggacgag gagcccgcgg ccggcggaaa ggcccgggcc gccgtgccga ggagcgcgat
     4321 gtccgcttcc gaggcggtct gtcccaggag ggtgcagggg gcgaggacgt cggcgccgag
     4381 cacccgcgcc gccgcgggcg ccagcggatc gtcacttcgc gtgaccacgg aagagagcag
     4441 gtcgaagtgg ttgcccccgc ccggagggcg gagacaacca cacgcgcgaa ttcttgaacc
     4501 gtctcgtcca gtgcggtcga agcgttcagt ccttcaggat ctaccgggcc ttccgatcta
     4561 tcgggcctgc cggtctttcg ggtccttcgg ccacgcttct agcgtttcgt cggccgcggc
     4621 gccggcgggg acaggaggaa tcccgctccg ccgatgagaa ggaccaggca ttccgcggag
     4681 tcgtggaagc tgccatcggc ctccacgggg ttcaggagcc cctctacgtc ttctgccagc
     4741 ttctccgtac gcgccgatgt ggtggacggt gtttcaacag gcaacataag atcaacccct
     4801 tgagagaatg ccgaatgcct gtatcgcact tcttcctacg ggtaattcaa cccccgtcgg
     4861 gcaggccggg caactcctga gcattcacgg agccgcgacg caggccacga ttacgcgaga
     4921 taccacaacg ccgattaccg ggaaggaaat cagcgccacg gagcacggaa ctcacgcgtc
     4981 ggcatatcgc actcgacacc gtggaattgc cgggtcagcg gtcgaggacc gtgaggtcga
     5041 gccgggcgag gcgttcgggg tcggcgagga tgtccagggc cacgaccttg ccttgcgcga
     5101 tcgtgaacgc catgaccgac agcggccgtc cctgcgacac cgccacgacg cccgcggccc
     5161 cgttgaccag cgcggccgtg cggcctcggc gaaccgggcg aaggtcatcg cccggccggc
     5221 caccgccgcc gcaccgcgca gcaccgcgcc cggccgctcc gtcccgctgt cggagcgcgc
     5281 cacgacgtcc gggtcgagga ccgcgacgag tgcctcgaag tcgcccccgc gagctgcggt
     5341 gagaaaggcg tcgacgactt cgcgctggcg ggcgaggtcg gtatcggggg ccggtgccgc
     5401 tccctgaacc cggcggcggg cgcggctggc cagttgccgg gccgccgtcg gggtacgtcc
     5461 gacgatcggg cctatctcgt cgaagggcac ggcgaacagg tcgtgcagaa cgaaggcgag
     5521 ccgctcggcg ggggccagcg tctccaggac cacgagcagg gcaaggccta ccgagtcggc
     5581 gagcagcgcc tgctgctccg ggtcgatgcc gtgcacgccg ctgacgagcg ggtcggggag
     5641 ccgtacctga tcctccatcg gttcctcgcg ccgtgcggtg cgggcgcgca gcatgtccag
     5701 gcagacccgg ccgaccaccg tcgtcagcca gccgcccaga ttccccacgg caccggtgtc
     5761 ggcgcggctg agtttgatcc aggtttcctg tacggcgtcg tccgcctcgc tcagcgagcc
     5821 gagcatccgg taggccaccg cccgcaggtg ggtccggtgc tcttcgaacc gctccgccag
     5881 aaacccggtc tctcccgccc cgtacatccc actcgtctcc gtcgtcccgc tcatgaatcc
     5941 ctgctcctgc cctttgtcct gcggtctcgc cgtccgtcac agcactccgt cacagcactg
     6001 acgtacggaa cccgctcgat gtgacgggcg ggcgcggcaa acataaccgg gccgacgccc
     6061 tcgtccagga ggggaccgac gcgctcatat gcacttcacc tcaagtgact tgtccgaccc
     6121 gcggtcgttg tacgggcagc gcagcggaca ggagcgaccg gaccggagcg aacggaagcg
     6181 gacgggaatc ccgccgacgg ggtaccggcg gaggccggga cgagcgggaa aagacgggaa
     6241 agacctggag ccgggccggc ccacggcacg gtcacagggc ccgtacgaca ggacaacggg
     6301 agaaaagggg ccgataccga tgacacagga acgcccagtg gtcgtcaccg gctgctcgtc
     6361 aggcatcggc cgggccgtgg tccggcatct tctcggccgt gaacacaccg tctacgcgac
     6421 ggcgcgagac atcggatcca taggggacct ggcttcggac ggagcgcgga tcctgcccgt
     6481 ggacctcacc gacgccggcg cgatgcgtga atgcgtacgg catgtggaag cccggcacgg
     6541 cgcggtatgg ggtctggtca acaatgccgg gtacgccctg acgggcccgg tcgaggaatt
     6601 ggacatggat caggtgcgcc agcagttcga ggtgaatgtc ttcgggcaca tcacgatgac
     6661 gcaactggtt cttcccggaa tgcgccggcg cggcgagggc cggatcgtca acatctcatc
     6721 ggtggcgagt cgcttcaccc tgcccggagg cgggtgttat cacgccagca aacacgcctt
     6781 ggcctccttc ggcgatgcgc tgcgctatga ggtgtcaccg ttcggcgtac gggtgagcgc
     6841 catcgaaccc gcggtggtgc gcacccggtt catcgtgacg gcggtgcggc tgctgaccgc
     6901 ccgcgggccg ggaaccgggg cgtatgcctc cttccgcgat gccctggccg actgttacgc
     6961 gcgcgtgcag cggactccgt accggtacgg ggcggtatcc gccgacaaag tagcccgtgc
     7021 ggtggggcgg gtgctggcat cggattctcc gggaccgcgc cacgtggtgg gcgcggcggc
     7081 gcgtctgacg gtggggctcc ggtggctgct gccggggccg ctgttcgacg ctgtggtgcg
     7141 tgcccgcttc cccgtcccgc gccaggaggg acgatcatga cccggcagtg gggtgtactg
     7201 ggagtcctgt gcctggctct gctcctgctg ggcgtggacc agacggtcct caacgtcgcg
     7261 ctgccgcaga tgcagcgcga tctccacctc ggttcggcgc agttgcaatg ggtggtgggc
     7321 gctcacatgc tggcgctcgc cgcgggggtg ctggcggcgg gcaactgggg tgaccggcgg
     7381 gggcggcgca gggcgctggt ggcgggcctg gtgatctgcg gtctggcgtc cgtactcggc
     7441 gccctggcgg acagcgcagc ggagatcatc gcggcccgtg ccgtgatggg gctcggcgcg
     7501 gccttcatca tgccctccac cctgtccgta ctggtgcagg tgttcccgca gccggcccgc
     7561 cagcgactgg ccatcaccat ctggtccacc gtcgccgggg tgggtgtcct tctcgggccg
     7621 gtgtcgggcg gctggctgct ggagcactgt tcgtggcggg cgtgcttctg gggcaccctt
     7681 cccctggtgg tgctgccgct gtgctgcgtc cccgtactgg tgccgccctg ccgcgacgac
     7741 caggcgccac caccggaccc ggcgggactc ctgctgtccg gggcgggcct gttcgccgtc
     7801 atctggagct tcatccaggc gccggtcctc ggctggaccg atcccctggt ggtgggggtc
     7861 gccgccctgg gtgccacgct gctcgcggcg atgatctgct gggagcggcg ggcaccggca
     7921 ccgatgctcc cgctcggatt cttccgcgac cgcggctacg cggtcgccgc gacgatgctc
     7981 tgcctgatgt tcttcaccct cgtgggagcg accttcctcc tcaccttcta cttgcagggc
     8041 ctgaaggcca tgtcccctct ggccgccggg cggaccctgc tggccggcgg gctcgcggtc
     8101 gccgtcggcg ggctcgtctc cgccgtcctc gcccgccgga cgcgggccag gacggtgatg
     8161 gccgtaggca tgctgctcaa cgtgtgcgcc ttcgtcgtcc tggccgggac caccgccggt
     8221 tcgtcgctga gccgcctgta cgtgttcctg agcctgatcg ggctcggtgt cgggctggcc
     8281 ggcgggcctg ccaccagcct gatcatgcgg gcggtcccac agcggcgggc gggcatcgga
     8341 gcgggggtga acgacgccgt acgcagtgtg ggcagcacct ccggcgtagc ggtcgtcggg
     8401 tcggtcttca acaccgtcta ctcctcccgg atcgcccggt cccccggcgc tccggtgccc
     8461 gcgggcgccc gggaccacct tctcggcgcg ctggcgcagg ccgaacggct cgtgtcccgg
     8521 gcgtccacgg gccgggggcg gctgcagccg tccgagcgcc tgcggctcct gggggcggcc
     8581 cggcatctgg ccgaggacgc cgcgcaggcg ttcaccgccg cgctgcgcac gacgtcctgg
     8641 ctgtcggccg gtatctgctg cgcggggtgt gcctggtact cggcgcgctg ccccgcggcc
     8701 ggtcggcggc atcaccaccg gcgccaccga ccccgccaca ggcagcggcc ccggtgcccg
     8761 ccgagcagcc ggacggggtg aggtgatgcg cggcacgctc atcgtcaacc cggcgtcgac
     8821 cggggccggc gacgcggtcc ttcgtgccgt cctggccgaa ctcactcccg tggtgcgcct
     8881 ggacgtcgcc gtcaccgcgt gccccggtca cgcctttcat ctggcccggg cggcgcggcg
     8941 ggacggcgta cggctggtcg cggtgctcgg cggggacggc accgtcaacg aggccgtcaa
     9001 cggcctgctg gccgacggat gggacgcggg gccacaccac cggccggccg tgcccgcact
     9061 gggcatcctc ccggccggag ggctcaacgt ggccgcccgc gcgctgggac tggggcggca
     9121 tgcggtgccg gccgcccgac ggctggccga ggcggtcggc caggggcggc ggacggtcgt
     9181 caatctggga aaggcggacc accgctattt cctcacggcc gccggagtgg gcttcggcgc
     9241 ggagctgatg gcactcgtcc aacaaggccg gcaagaaaac cgatgcccac cgggccgacg
     9301 gcaatcaagg tggcggcaac gaggccgggg cggtggccgg tccggcgcgt ggagccgcta
     9361 tctgatgccc gcggcacggc acttcctctc cggtaccgac cgcagggttc ccgccctgtc
     9421 ggtggccctt ccgcaggagg aaccgcagca gcgggccgag cggacggagg gggtcttcgc
     9481 gttgctggtg gccaacacct ctccgtacgc gtacatgggg cgttggccgc tggccccgtg
     9541 ccccgccgcg tccttccagg acgacctgga agcactggcg ttcacggacc tttccaccca
     9601 ccgttgcgcg gctctcctgg cccggatgct gctgcggccc cggcacgagc acaacggcag
     9661 accggtacgg cgtttcgccg gccggcagag cctgtcggtc accgtgaccc ggccggtggc
     9721 cgtccatgtg gacggcgaag tcctcacacc acggcgggag gtgcggttct cctcgacccg
     9781 cggagcattg gccgtcgccc tgtgacagac cttccctccc cttccctccc cttctcccac
     9841 cttccaccgc cgccgaacgc ctgcttgaga aaaggacatg gtgaggaaaa ttcctgagca
     9901 ctactcgccg gtgaactccg gtaccggtac gagcgacgcg ccgggctctc gcgcgcgagg
     9961 acggatgcac tccgggcggc cgggtagccg gcagcagggc gtggagcttc ctggggcgct
    10021 gcgcagggac atgcgccggt tcgccgcgca gctcagcgcg catatcaacg ccctctaccc
    10081 ggacaccaac gccctgaacc tcgatgtcac ccgcgagttg ctcgggctgt caccggacca
    10141 ggaactcccg cccgcgctcg cggggcacgt ccaggaccgt gtccaccgga cgctggtgcg
    10201 gccggtgcgc cacctcgtgg acgccggcgg ccagcgctgg cggccctatc tgctggcgaa
    10261 gatcattcac gtgctcgggg gcgacagtgt cttctacacg cctctcctgg cagccggtga
    10321 actcatgcac accggctcgc tgatcatcga cgacgtccag gacgaggcac ccgtacgacg
    10381 gggcagagcc gctgcccaca ccgtctacgg cacgcccacc gcactcaacg ccggcaccgc
    10441 cgccttcttc gcgttcgacc gggcgctgcg ccgggttgtg ccggacgacg tggtgctgcg
    10501 ctgcgccgta caggacgcgt acctgtcggc gctgcgggcc gcgcacgccg gtcaggccct
    10561 ggacatcctc ggcctgcgcg aggagatgga cacggccgtg gccaccggga acgccggtcc
    10621 cctcctggac caggtgcggc tcacccaccg gctgaagtcc ggggccccgg tccgggcggc
    10681 cttccacgtc ggcgccctgc tcgtgggctc ctccgccgaa ctgtccgggg cgctgcaacg
    10741 attcggcgag gccgtgggca ccgcgtatca gatcaccgac gacgtactgg atctgcgcgg
    10801 tgtggtccgg gccggcgccc cgacgaagtc cgtcgccgag gacctgcgca acggaaaggt
    10861 caccatgccg ctggcccacg cggtggcgtt gctgccgcgc cgggacgtcg aggccgtctg
    10921 gcacctcgtc cgggacgggc acctgagcga ggacggcgtc cgggaggcga tcggtgcgct
    10981 ggagacctgt ggcgccgtcg acgcatgtgt cgacgaggcg gagcggatgc tgctggcggc
    11041 ctgggaacag gtgaagccac tgctgccggg cacccggcag agctgcttca tccacgcgct
    11101 ggcccgccat acggtgcggc gggtgcgcgt ggcctgaacc ggaccagcgg cgatggcagc
    11161 ggtggtgagg gcgagggtga tgacggtggt ggccgtaccg tcgccgggac gagccgtggg
    11221 cgggcggtcg tcagcggttc cggcgccacc gagggtctac cggggaaggc tcgctcaccc
    11281 gaagtccgcg atgccgtagt cgccttgggt gccggggtag ctgcgtacct tcggcgggtc
    11341 gtcgtagtac gagcggcggc gggccggccc caggcgctgc acccgggccc gggcccggag
    11401 cgtcccccgg acgaggtacg gcagcagccg cggctcgcgg tacccgaaag ccgtacgcag
    11461 cggcggatcc atgaggccga cgacaacccg gcgcaccacc ggccgcaccg gcgccgggaa
    11521 ccaccggccg accacaccga gggcctggtc ggccaccctg cgaccactgg gcgcggtggc
    11581 gaaccgggac cgttcgtatt ccctgttgaa ttcttcgaac tgcgtgtagt cggagggaat
    11641 tccctggatg ttcatccgct ctccgacatt gcggtagaac cagaaggcgg ccagcttctc
    11701 ctgttccagc agcgggcgcc aaccgtaggc gtcgatccat ctgatcggtt catggacgaa
    11761 tgccgagagc gtatacagca tgtcctcgtt gctgatggcg taccagcggt gtgccctgtt
    11821 gatcgtccgc agtgcggtcc tccctccggg gagtcgtatc cgtacttgac cagagccgcc
    11881 atgagaacga gcgtgtcgtc ataccggcgt tgtccggccc gcgcgaactg gcatgtggcg
    11941 tccagcagtc cgccgatccc ggggacggcg aaggtccgga tcagtgccga ttccagggcc
    12001 cgctgatagt cccaggggaa ttccaggccc gaactgatgc ggtagatctc caggtggtca
    12061 cgcatcccgt cgagcgtcac gatccgccgc gcgttcccgt aacggtccgc gaatacccgc
    12121 accatgtgaa catctcccca tcacgctcac gagttcttcg gccgcgcacg gcctgggacc
    12181 ttggccccga cctcgatccc gacttccgct gaatcctagt aggatccgtg aactttcctt
    12241 tccgatcgaa tgacgaatac accgacggca tggcagcagg ccgcgaaacc acatcgcccc
    12301 cggcggcaga ccccaccgct acgccaaccc gcgcgatccc cctggccggc cgcaccggac
    12361 ttcccctggg acgggccgtg gtcgacaccg gcacggacac tcatagcggt gccggcacag
    12421 gtacgggcac aggatccggc gccgccgggt acaccctcag catcgcgccg ttcaccggcg
    12481 caccgctggg ccgtgtgccg cactgcgggc cacgcgacct ggaccgtgtc ttctcccgcg
    12541 cccgtacggt ccagcgcgcc tgggcggaga ccggcgtacg cggccgggcc gccgtcctgc
    12601 tccgcttcca cgacctgctg ctgcgccacc gggacgacct gctcgacctg atccagtacg
    12661 aagcgggcaa ggcgcgcgcc cacgccttgg aagaggtgat cgactgcgcc ctgaccaccc
    12721 gccattacgc gcgccgcgcc cccgccctgc tgcgcccacg gcgccgccgc ggagccctgc
    12781 ccctgctcac acatgtggtg gaacaccgcc gcccccgtgg ggtcgtcggc gttctggctc
    12841 catggaacta cccgctcacc ttcgccgtct gcgacaccgt gcccgcgctg ctcgccggta
    12901 acgcggtggt gtgcaaaccc gacgtccaag gggcgttcac cgcactgcgg gtacgggacc
    12961 tgctgcacga ggcgggactg ccgcacggtc tgcaccaggt cgtcacgggt ccgggcgatg
    13021 aggtcggccc ggccgtggtc gcccgcagcg atcatgtgac gttcaccggc tccaccacga
    13081 cgggccgcag cgtcgccgcc ctggccgggg aacacctcat cgactgcacc ctcgaactcg
    13141 gcggcaagaa cgccttcatc gtgctggacg acgccgacct ggacaccgcc gtacgcggtg
    13201 cggtgcgggc ctgcttcacc ggtgccggtc aactgtgcat gtcggccgag cgggtgctcg
    13261 tccacgccga tcgcagtgcg gacttcctgc gggccttcgc cgccgccacc cgcgcgctgc
    13321 gcctgggcgc cgccttcgac taccgggccg acatcggctc gctggcctcc gcggcccggc
    13381 tgcgtaccgt ggacgaacac gtccgggacg cgaccggcaa aggtgcttca ctggtaacgg
    13441 gcgggcgtcc ccggccggac gtggggccct tcttctacga gcccacgatc ctcaccgggg
    13501 tcaccgacgc gatgagcatg tacggccagg aggtcttcgg gccggtggcg gccgtcgcct
    13561 cgttccggga tgaacaggac gccgtggagc aggccaacgc cggccgcttc ggactcaacg
    13621 ccagtatctg gacctcccgt cccgccgcgc acgggccctg gccgcccgca tccgggccgg
    13681 tacggtgaat gtgaacgaac cgtacgcagc ggcgtacgcc tccgtcgacg cccccatggg
    13741 cgggatgaag gactcgggcg tcggccgccg gcatggccgg gacggcctgc tgagctacac
    13801 cgaagcgcag accgtcgcca cccagcgcct gctgcccctg acaccgccgg acaccctgtc
    13861 cggacagtcc tatgccactt tcgtcacacg tctgctgctg ctcgccaagc atctgcgtgc
    13921 atgaaatctc aacggggcga accatgacga ccgggcggat gccgcccctc ccggacaccg
    13981 gctcagtggg tggcgagcca ggcgattccg gcaccggtca ggacgagggg tacggcccat
    14041 gaggccacgg cgacccggcg gaggagatat ccggcgacaa aggccgtgcc gagaacggcg
    14101 accgttccca ccgtccccgg cagcagaccg tggctgtagc cgaagtcgtc ggcataacgc
    14161 agccacctga gccatccgaa tgtcattctc accctcccct gacgcaccga tcaccgctcc
    14221 gccggcacgt cacagcggcg aaacacggcg gaacgcggcg gaacacagcg gtgcgcaggg
    14281 gcgatgcagc ggggatcaac gtaacaagtg gcagcgcccg gttgacgagc gggggacgcc
    14341 tgccctgatg accggaggtg gtcagccgcc gcggtagtgg tcggcaaccg cggcgaaggc
    14401 ggccttgggc tcccagggca ggtcggggta ggtgtcgccg tggcggtctt cgaggacctt
    14461 gacgacaccg aggctggcga ggtcaagatc gtcgcgggca tcgccgtcag ggcggtgggg
    14521 caggttgtgg accgcgaaga ggaacacgaa ggcgctgtcg acaccctcgc tgtcgaaaat
    14581 ctccagcagc tcacgcacgt acgccgcttg gccggcctcg tcccgctcgt acttcccgga
    14641 cagccggagc ggcgcgccgg tggcttcgtc gtattcgaga attcccatgc tgcgcggtgc
    14701 catgtcaccc gcgccgcgcc aggtggcggt cccgaagccg gtgatggcga ccggtttggg
    14761 ctgtgcggct tcgggctgtg cgaccaggct gcgtacgccc tcccggaatc ggtcggccac
    14821 ctccgcggac cgaatgagtt cgtacgtcat gaagtcgaac acatcccagt cgacgccttc
    14881 gaactgtatg acggcgtacg tgactttgcc gtggaagcgc tcgcggacca tcggcacggc
    14941 ttcgcggaag aaggcgttga ggcgggcggc gaccgcggcg aatttctcgg gccgacgggc
    15001 cgggtcgccc agcagccggc cgagtcgctc ctcggtgctg tcgccttcga ggaacccctg
    15061 gttcatgacg ctcagttcga cgcccgcaac gaacacgacc tcggctcccc gcgtccggag
    15121 tcgctcggcc cgcgccgcac agtcggctaa cagggtgagg atctcatcgg tggtcagctc
    15181 caacgggtag ggcgagaacc agacctccag tcccaggtcg gcggcgcagc gggcggcgaa
    15241 ctccaggcgc tccgggtcac cgccggtgat gtggacggcg ttgcagtgga ggtcgtcgcg
    15301 gatgacggcc agctcccttg tgaccaggtc cggatcgaag cgctcccggg agttggtgcc
    15361 cttgcggagg aagccggtgt cgtagcagat gcctttggcg cgcatacctc tgaccttcct
    15421 gtcggggctt gcgggttccc ggagcactgc accggaccac gcaatcccgc tgctcgcgtg
    15481 ctgatccggt tccgaggctg ccgtgccgca ggcccgttct ccaggccgga ccacgggcgc
    15541 acgggtgtgc gatacgggcg cgtcggcgca ccacggtcag gcactcatat ggcgcgtcgg
    15601 ttcacgctgc tccatatgag tgccgggacg gttttacggc aaggtggcgg cgggtgcgag
    15661 ctggtcggcc gcgaagtcct ccgccgagcg cggcgggcgg ccgagcacac gccggacgcc
    15721 gtccccagcc ctgcgacgcc ttcccggcgg tagttggtgt acaggtcgcg cagaccgtcg
    15781 acgaccggcg cggggacccc gcgccgtgcc aggtcctcgc gccaggcgtc gtccaacggg
    15841 acgtcgacgt accgtacccg cctgcccagg gccgcgccga agcgtatggc gagttccggc
    15901 agggtcagcg cgtgcgggcc gctgatctcg atgtcgccgc cgaccggacg gtccgcgagg
    15961 agttcggcga gcgcgacctc cgcgatgtcc cgtacgtcca catacccccg ggcaccggcg
    16021 ggccctgcgg gatcggccag cgtaccgccg gcgatcgccg ccgcggccgt gaggaagttc
    16081 tgcaggaagc ggtcgggccg cagaacggtc agttcgggaa caccggcccc acgcagtcgc
    16141 ccggcgatga cgtcgtggtt gccggtgacg gcatccggta cggtcccggc gcccgtgaac
    16201 gcccgggcac cgagcttgac gatccgtcgc acgcccgcct ccagggccgc caggccaagg
    16261 cccgtctcga cggcgatctg gtccacgctg aaggggtgcg ccaggtaaag ccgttcaact
    16321 cccgccaccg cgcggcgcac gtcgtccgcg tctgcggcgt ccccgcggaa cacctcaccg
    16381 cgcacctcgc ccagcgcccg cgcaccggct tcggagcgga cgaggaagcg tacgtcctca
    16441 cggccgcgca gtgcctcggt cagatggcgc ccgaccccgc cgttcggcgt ggtgatcaag
    16501 attgtcatcc gttctctccc gctccacgta ccctcaagat cgtttcgctt gggcaacggc
    16561 gtccggccaa ggcgcattcc cggtcggccg cgggggtgcg tgggggactg tccgatcggc
    16621 cggggaggtg cgcggggcaa ctgcccgtat cacagcgggc ggatcagcga agtgccccac
    16681 ccataaggca ccgtgcctcc ttcgccctcc ccctctccct cacagccgcg ggtgaaccgg
    16741 cccctgcgtg tcgcgcagtg aggcgacggt cgcaccgcgc actccgcgga gcgcgatgat
    16801 ctcggcgcag atggcgacgg cggtttcctc gggcgtacgg gcgccgatgg cgagcccgat
    16861 gggggacatc agccgttgca gttcatcggc cccggcgccg gccgcgcgca gccggtcccg
    16921 gcgatcctcg tgcgtacggc ggctgcccat cgcgcccagg taaccgacgt cggtccgcag
    16981 ggcggagagc accgcgggga cgtcgaactt ggcgtcgtgg gtcaggacac agacggcgtc
    17041 gcgcggtccc aggccggtgc cgacgcggtc gaggtagcgg tgcggccagt cgacgacgat
    17101 ctcgtcggcc atcgggaagc ggcggtgggt ggcgaaggtt gcacgggcgt cgcacacagt
    17161 gacccggtag ccgagcagct tggcggcgcg cgccagggcc gccgagaagt cgacggcgcc
    17221 aaggatgatc atgcgtggtg gcggtgtgta ggtgtcgatg aagacggtcg tcgtcaccga
    17281 gggcgcgacc gaccctgtag tggcaccgag ggtatcggtg gggttggtgg cgttgatggc
    17341 gttggtggag tcagtggtac cggtgtatgt acgcagcgcg ttgacgccgt ccgcgatcgc
    17401 ctccccggcg tcccgcagcg ccgcacggac accgaagtcc ccgggggcgg gcgggccgtc
    17461 gggccgtacg agcgccttgg cgcccgtacc cggtccgtcg atcaccgtga cgagcgcgaa
    17521 gggccgctcc gcgcgcacgg cgtcagccac cagcagatgc gtcgcatcca gctcctcgat
    17581 gaacagccgg accgtgccac cgcaggtgag gccgacggcg aaggcgtcct cgtcgctgta
    17641 gccgaaggtc accagccggt ggccgcctct cgccaggacg tccagcgcct cggcgacgac
    17701 cgcgccttcc acgcagccgc cggacacgga gcccgccacc tcgccgtcct cggtgacggc
    17761 catggcggcg ccgggctgcc gcgggccgga tccggacacc tccacgacac gggcgacggc
    17821 cacccgcctg ccctcggcgc gccagcggtc caggtcgtcc aggatctctt tcacagcagg
    17881 tcctccgcgg tgatcggcag gctgcggatc cggcggcccg tggcgtggtg gacggcgttg
    17941 gcgatcgcgg cggcggtgcc gttggagccg atctcgccga tgcccttggc gccgatggcg
    18001 ctggcgtgcc ggtcctcgtc ctcgatgaag gagacgtcca ggtcaccgat gtcggcgtgg
    18061 acggggacga cgtacccggc gaggttcttg tgcaggaagc ggccccgccc cggctccatg
    18121 acggaacgtt cccgcagggc ctggccgagg ccccagatga tgccgccggt caactggctg
    18181 cgggcggcga gggggttgat gatccggccc gccgagtaga cgccgacacc gcgggtcata
    18241 cggaccagcc ccaggtcggc gtcgacccgc acctcggcga agaacgctcc gtagaccagg
    18301 gcggagacct ccgaggcggt gccgttgggg tgggcactgg cctcgggcgc ccagttgccc
    18361 tcggcctcca gcgtgtcgat gcccgcctgc cgcattccct cgaagccgcc cgcggccgtc
    18421 agcttctccc gcagggcggt ggccgccacg tggacggcgg agccgacact catggtcgtc
    18481 atggaaccga acaccccgcc gtgcgcgggc agatcgctgc tcccgtgccg gacctcgatg
    18541 tccgcggggc cgatgccgag tgcttgggag gcgaccgcct gcaccatcgc cggaataccc
    18601 gtgccgatct cctccgtgcc ggtctccacg acgatccggc ctccggcacc ggcccgtatc
    18661 ctggccgcgg cgggcccccg gaaggagtcc atcaccgcgg tggccacgcc ccagccgatc
    18721 aggtcgtcgc cctcgcgcag cgaaccggcc ggcggccgtc cgtcccagcc gaagcggcgg
    18781 gccccctcgc gcagacactc caccaggcgc cgcgaggaga acgggcggcc cgtcatgggg
    18841 tgcactgtcg gctcgttgcg tatccgcagc tccacggggt ccatgcccag ttcgtacgag
    18901 agctcgtcca tcgccgactc cagggcgaac agaccgacgc cctcgttggg cgagcgcatc
    18961 ggggtcggcg cgggccggtc gacctgctcc accctggcct tgagggcgat ggcagggctg
    19021 gcgtacaggc tgccggagcc ggcggtcgcg gcctcgatgt ggtagtcggc ggcccgtgtc
    19081 gtggcgttgg tgctgcggtg ctccagagcg gtcagccggc cgtcccggcg ggccccgatc
    19141 cgtacgcgct gccgggtggc cgcctggtgc ccgcacagcg tgaaggtctg cgccctggtc
    19201 agtacgagcc ggaccggccg cccggcgacc cgggcggcgg cgacggccag cggcacgggc
    19261 tgctggagga acgccttgga cccgaatccg ccgcccacat agggcgagtg gacggtgacg
    19321 ttctggggcg cgacgccgaa gagggccgcg actgtgcctt gggtcagcgc caccgcctgc
    19381 gtcgacacgt gcagggtgag gcggtcttcc tcccaccacg ccagtacggc cggcggctcg
    19441 atggcgttgg cgtgccggtc ggaggtggtg tacgtggcgt cgaccaccac gtccgcgcgc
    19501 gccaggcccg cttcgacgtc accgacgccc acatcgggtt cctcgcgcag cagcatcggc
    19561 cccctggctt cgatctccgg ggcggctccg aacatgacgg gctcgaccac gtcctcgtac
    19621 gaggcgtcga ccagggaggc cgcgtaccgg gcctgctccc aggtgcgggc caggacgacg
    19681 gcgaccggct gtccttcgta gtggatgcgg tcgtcctgca tgaccagcac cgtgtgcccc
    19741 atagggggcg agggcatggg gttcaggcgc ggcatgtcct gatggcggat gacgcgtacg
    19801 acgccggggg cgcgctcggc cgccgccgtg tccagggcgg ccagccggcc ggtgggtacg
    19861 gtggcggtga ccagggccgc gaccagcgca tccggatgcg gacggtcggc ggtgtagagg
    19921 gccgctccgg tcagtttggc gggaccgtcg ggcctgcgga ggccctgagg ggcggaaccg
    19981 ccgggcctgt gcggaccctg aggggctgga tcatcgggcc tgcgcacccc ctgaggggcg
    20041 ggtccggtct ttccgttcgt cttcacgcgg cacctcccgc gacacgcagc gcccgtaccg
    20101 ccgcgcgctg cgccagctcg atcttgtacg cgttgtccgg cagcggcaag gcgtcctcga
    20161 aggatgccgc cacggccgac cgcagtccgt ccacgtcact cagtgcgacg cccaccagcg
    20221 cgtcctcggc ggcccacagc cgccacggcc ggggcgcgac actgccgagc gccagccggg
    20281 cccggttgat cacctcaccc tccacctcga cgctgacggc gacggagacc agggcgaatt
    20341 cgtaggaggc ccgctcccgt accttcaggt accaggaggt gccgtggtcc ggcgggacct
    20401 cgacgccggt gaccagctcg tcgggccgca accgggtgtg cagttcgggc cggtcctgcg
    20461 gcaaccggtg gaattcggtc acgggaatgc gccgccggcc cctccggccg ctctccgtca
    20521 cgaccaccgc gtccagcgcc gccagtgcga ccgccaggtc ggacgggtgg gtggccgcgc
    20581 acgccgggct ccagccgaac agcgcgtgcg caccggtgtc gccgcccgcc agcgcggcac
    20641 agccggagcc cggctcccgc ttgttgcacg gcagggcggt atcggcgcgg aagtacgggc
    20701 agcgggtgcg ctggagcagg ttgccgccga tgctcgccat gttccgcagt tgcgcggagg
    20761 ccgagcgcag cagcgactcg gtgatcgccg ggtatctccg ggcgacttcc ggatgggcgt
    20821 gtacatcgct catacgggcc agggcgccga gcctcagtcc gtcgtcatcg acgtcgatgc
    20881 cgtccagagg gaggccgttg atgtccacca cccgctcggg gcgttcgatg ccttccttga
    20941 gccagttcag cagctcggtt ccgccggcga ggagctgtgt ccccggttcg gtacgggccg
    21001 tcagcgcctg ctgaagggtg gtggccctct cgtacgtgaa ggtcttcatc ggctggtgct
    21061 ccccgttccg ccgtgtccag gggcaacggt tcctgggaca acagtcccgt aggcaacaga
    21121 cccgtgggca acagtcc
//
