LOCUS       NZ_CP074380            22643 bp    DNA     linear   CON 27-MAY-2024
DEFINITION  Streptomyces sp. MST-110588 chromosome, complete genome.
ACCESSION   NZ_CP074380
VERSION     NZ_CP074380.1
KEYWORDS    RefSeq.
SOURCE      Streptomyces sp. MST-110588
  ORGANISM  Streptomyces sp. MST-110588
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1  (bases 1 to 7915503)
  AUTHORS   Booth,T.J., Bozhueyuek,K.A.J., Liston,J.D., Lacey,E. and
            Wilkinson,B.
  TITLE     Bifurcation drives the evolution of assembly-line biosynthesis
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 7915503)
  AUTHORS   Booth,T.J., Bozhueyuek,K.A.J., Liston,J.D., Lacey,E. and
            Wilkinson,B.
  TITLE     Direct Submission
  JOURNAL   Submitted (10-MAY-2021) Molecular Microbiology, John Innes Centre,
            John Innes Centre, Norwich, Not US or Canada NR4, United Kingdom
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: 28-FEB-2016
            Assembly Method                   :: HGAP v. 3.0
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 25.0x
            Sequencing Technology             :: PacBio RSII
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_022695595.1-RS_2024_05_27
            Annotation Date                   :: 05/27/2024 05:38:09
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 6,918
            CDSs (total)                      :: 6,828
            Genes (coding)                    :: 6,327
            CDSs (with protein)               :: 6,327
            Genes (RNA)                       :: 90
            rRNAs                             :: 7, 7, 7 (5S, 16S, 23S)
            complete rRNAs                    :: 7, 7, 7 (5S, 16S, 23S)
            tRNAs                             :: 66
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 501
            CDSs (without protein)            :: 501
            Pseudo Genes (ambiguous residues) :: 0 of 501
            Pseudo Genes (frameshifted)       :: 350 of 501
            Pseudo Genes (incomplete)         :: 185 of 501
            Pseudo Genes (internal stop)      :: 14 of 501
            Pseudo Genes (multiple problems)  :: 45 of 501
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 12:56:23
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 35930
            Orig. end                         :: 58573
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP074380.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            Bacteria and source DNA available from Barrie Wilkinson, John Innes
            Centre, Norwich.
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..22643
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="lassopeptide"
                     /region_number="1"
                     /rules="(PF13471 and Asn_synthase or micJ25 or mcjC)"
                     /tool="antismash"
     cand_cluster    1..22643
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PF13471 and Asn_synthase or micJ25 or
                     mcjC)"
                     /kind="single"
                     /product="lassopeptide"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..22643
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:12643](+)"
                     /cutoff="10000"
                     /detection_rule="(PF13471 and Asn_synthase or micJ25 or
                     mcjC)"
                     /neighbourhood="10000"
                     /product="lassopeptide"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..12643
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="(PF13471 and Asn_synthase or micJ25 or
                     mcjC)"
                     /neighbourhood="10000"
                     /product="lassopeptide"
                     /protocluster_number="1"
     gene            956..1474
                     /locus_tag="KGS77_RS00160"
                     /old_locus_tag="KGS77_00170"
     CDS             956..1474
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF024950.4"
                     /locus_tag="KGS77_RS00160"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KGS77_00170"
                     /product="SDR family oxidoreductase"
                     /protein_id="WP_242577844.1"
                     /transl_table=11
                     /translation="MSRARGRDLATATAADGSAAYALNAGHAQRLMPAALPHLRAAGGE
                     SAVLNSFISRWKPSPQAKYGAAKAALLSTAGTLANDLGPGHVRVNVYSPGRCSFPAAAG
                     PGCRNRNLRRSPASPHSSRAGSWSHRRRTPAPSCRPHRRIPALALVQRCLRCPHPRRPG
                     TKRPTPDGY"
     gene            complement(1479..2348)
                     /locus_tag="KGS77_RS00165"
     CDS             complement(1479..2348)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="KGS77_RS00165"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_242577852.1"
                     /transl_table=11
                     /translation="MITAFDQVDNTFGGQEVRSSILFYLHHEVLPMLRRGMSAEERGPL
                     FTAAARLGALAGWSSYDSGEYGLAQRYMIQALRLCQEGGDLVLAGQILAGLSHLSTSLG
                     HPQDGVHLARAGLQTARHAGSPLGLMRLHMMVARGCAASSRPKQALRALEDAEAALGRS
                     RGAEQESPWVRYLDRHYWEAEAAFVFRDVGEAGQAEQMADASVRANTDRRRRQAISQAM
                     LATACLQQQRLDEALACAHAALKGLELVRSQRSVQALRDFGQRVSVFNKEPAVQGFLRA
                     AQPVLQTA"
     gene            complement(2345..2764)
                     /locus_tag="KGS77_RS00170"
     CDS             complement(2345..2764)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="KGS77_RS00170"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_242577854.1"
                     /transl_table=11
                     /translation="MNALARRQGRGTRYDKASVSRWIGGRPPRTETIWLVAGVLTEALG
                     RVVQPCDIGFAAQQGPPVVIRSLRYGEDVGEVLQTLSDLTADDVGCRDVLGLVPFVSSA
                     LLAPQRGWLLWAWEQSEAPAPAAVSAGAGWRWCRR"
     misc_feature    complement(2750..2763)
                     /note="TFBS match to ArgR, Regulator of arginine
                     biosynthesis genes, confidence: weak, score: 17.46"
                     /tool="antismash"
     misc_feature    3060..3074
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence: weak,
                     score: 17.73"
                     /tool="antismash"
     gene            complement(<3170..3547)
                     /locus_tag="KGS77_RS00175"
                     /old_locus_tag="KGS77_00180"
                     /pseudo=""
     CDS             complement(<3170..3547)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PCMT"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006346494.1"
                     /locus_tag="KGS77_RS00175"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /old_locus_tag="KGS77_00180"
                     /product="methyltransferase, FxLD system"
                     /pseudo=""
                     /sec_met_domain="PCMT (E-value: 7.4e-17, bitscore: 60.4,
                     seeds: 9, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRLASPSLTQKEPHQLVERGEIVSKNVEAVMRKVERHRFTPGASL
                     EDAYRPCNALVIKRNKRGVAASSVSAPQTQAFMLEQAQIRPGMRVLEIGSGGLSAAYLA
                     ELVGEGGEVTTVDIDPEITGRA"
     misc_feature    3542..3557
                     /note="TFBS match to LexA_variant_1, Repressor of DNA
                     damage response, confidence: weak, score: 20.2"
                     /tool="antismash"
     misc_feature    complement(3547..3563)
                     /note="TFBS match to GnfM, Regulator of nitrogen-fixation
                     genes, confidence: weak, score: 19.36"
                     /tool="antismash"
     gene            3607..3945
                     /locus_tag="KGS77_RS00180"
                     /old_locus_tag="KGS77_00185"
     CDS             3607..3945
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018895668.1"
                     /locus_tag="KGS77_RS00180"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KGS77_00185"
                     /product="hypothetical protein"
                     /protein_id="WP_242577863.1"
                     /transl_table=11
                     /translation="MALVSKGSRRIVVDGETYRWRLRRRPTYSQGLCWTPCTYAVEHAD
                     RPGTSLVITTDQPHSSNWIGRTGTPILPSDVTDHIRTALARGWAPDRPGSPFELDLSHG
                     FVSGYGSL"
     gene            complement(3958..>4212)
                     /locus_tag="KGS77_RS00185"
                     /pseudo=""
     CDS             complement(3958..>4212)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003979132.1"
                     /locus_tag="KGS77_RS00185"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /product="ISKra4 family transposase"
                     /pseudo=""
                     /transl_table=11
                     /translation="LHYDRALQAGWPIATGILEGAARHLVADRLDIGGARWGLDGAEAV
                     LELRTVAANEDRDACWEHYRAAEHQRLYPAGQHRYALTT"
     misc_feature    4327..4340
                     /note="TFBS match to RpoN, Regulator of nitrogen
                     assimilation and virulence, confidence: medium, score:
                     16.73"
                     /tool="antismash"
     misc_feature    complement(4501..4515)
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence: weak,
                     score: 15.82"
                     /tool="antismash"
     misc_feature    4502..4516
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence: weak,
                     score: 15.79"
                     /tool="antismash"
     gene            complement(4523..5221)
                     /locus_tag="KGS77_RS00190"
                     /old_locus_tag="KGS77_00195"
     CDS             complement(4523..5221)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="KGS77_RS00190"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="KGS77_00195"
                     /product="hypothetical protein"
                     /protein_id="WP_242577865.1"
                     /transl_table=11
                     /translation="MTETVDDVREAAETVPTPWPGLTPLADLSFRHKAGIVAQRGSREA
                     KVGRDIAVHAARAGTPVVLFTGYPPATRPASLFIDMTPTPTAAHINLSAQRLIAGRKPR
                     LIVIERFERLSQDTPEPQWDDAPGDPVEDPASESWGDRLMWTVRDIRVEIPTLFTTVVD
                     PVPDLTRPLFKWLDVDHPAMVMTDVCKPTLVVARTGPEAVEGRLEVDPLAFRTGSVFTL
                     KWAPLATQTR"
     gene            complement(5337..6359)
                     /locus_tag="KGS77_RS00195"
                     /old_locus_tag="KGS77_00200"
     CDS             complement(5337..6359)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004950975.1"
                     /locus_tag="KGS77_RS00195"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KGS77_00200"
                     /product="hypothetical protein"
                     /protein_id="WP_242577867.1"
                     /transl_table=11
                     /translation="MSTFLRPSADRAVIRCDQCPGRPVLPTHREETDTRRCVRCQGEHR
                     WLAQPHPDDHLCSVCRRECPSCQALTSNGERCRTCRDRCRTCSGPLPERPEYAAGITRV
                     EPEKRKDRRRKWARIYFPRSWDRDQCDACQTAPSAKDPLRAVLAALPDKLVLACGGGVP
                     PAVVDLVHDELRRHTPARLAARIERRWWKSWSSRPLKRKADGHRDGYGPDDVAVWLLAP
                     TACHGHCEDGWLPAPPERPDRDDEPCTVCRGGRLLAPRRDEAEEDDEAEGQPASARSLA
                     DAISYRPPIPECTGRGGTCGRPVTPPHTQCPECLDWPWCICRRRRHNPEQAACPACATR
                     "
     gene            complement(7027..9186)
                     /locus_tag="KGS77_RS00200"
                     /old_locus_tag="KGS77_00205"
     CDS             complement(7027..9186)
                     /GO_function="GO:0046983 - protein dimerization activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016575907.1"
                     /locus_tag="KGS77_RS00200"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KGS77_00205"
                     /product="alkyl sulfatase dimerization domain-containing
                     protein"
                     /protein_id="WP_242577868.1"
                     /transl_table=11
                     /translation="MPESSTYLQPVEPSVAVAAGNRKAAEAANAADEKDGRDFADAIRF
                     QIAPPDVPVIMSRKDPEKVVWDFTAYDFLNPETRMEMPSVNGSLHRQGELTAVAGLFQV
                     TSCSQYRIYQVRGYDLSNMTIIEHDSGLYIIDPLASYETAQAALKLFRDKTELTKELRP
                     VKGLIYTHCHVDHFGGARGIFSEQGDPLEPGVPVVAPDGFLEHAVSENIYAGPAMARRA
                     QYMYAAQMDKGPAGQVGSGLGLTISTGEVTLVPPTVYIGGPAHQPVAKGNWQPSYVIPW
                     RPGLYVFDGFGFPLVFQLTPGTEAPAEMNIYFPDARTLCIAENATHTMHNILSLRGAQV
                     RDAHAWSKYLTEAIQSFGKETDVLFASHHWPMWNEVRDEGGEEGPGNERILEFLNKQRD
                     MYGYLNDQALRMINAGYTGPEISEQLQTLPPSLADHWYDRGYYGSVSHNFKAVYQRYMG
                     WYDGNPAHLWELPPVQAGAAYVEAMGGAEAVVDAAQRAYDRDTPDGFRWAAELLNHVIF
                     ASAAETGSPLAEPQVTRARELQSKVFTQLGYGSENGTWRNAYLTGAQEVLGGPQPLITS
                     QTSADLIRSTTLEQYFSALARSVDGPTAAEQYREPIALNWVFTDENGVETGQKCTTTLR
                     NGVLVFVEGGDRFVQAPAATIRLSRQALDELAESPGFKDNFNNAVQDKKITLEGAKAQA
                     ATDAVFGTLTLPDPKFPIVTPRKHI"
     misc_feature    complement(9334..9349)
                     /note="TFBS match to LexA_variant_1, Repressor of DNA
                     damage response, confidence: weak, score: 20.08"
                     /tool="antismash"
     misc_feature    9679..9690
                     /note="TFBS match to CcpA, Catabolite control protein A,
                     confidence: weak, score: 16.0"
                     /tool="antismash"
     gene            9751..9858
                     /locus_tag="KGS77_RS00205"
                     /old_locus_tag="KGS77_00210"
     CDS             9751..9858
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF039305.3"
                     /locus_tag="KGS77_RS00205"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KGS77_00210"
                     /product="keywimysin-related RiPP"
                     /protein_id="WP_242577869.1"
                     /transl_table=11
                     /translation="MTYERPTLTKVGGFRKVTGVKNTGPKDVLGGKQLL"
     gene            10001..11919
                     /locus_tag="KGS77_RS00210"
                     /old_locus_tag="KGS77_00215"
                     /pseudo=""
     CDS             10001..11919
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lassopeptide: Asn_synthase"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1177: asparagine synthase (glutamine-hydrolyzing)"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_053804306.1"
                     /locus_tag="KGS77_RS00210"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /old_locus_tag="KGS77_00215"
                     /product="lasso peptide isopeptide bond-forming cyclase"
                     /pseudo=""
                     /sec_met_domain="Asn_synthase (E-value: 1e-31, bitscore:
                     109.5, seeds: 78, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEESLSLSALPGWFVVLPDTDAVATVAAKALSHASHSLPHASGRP
                     WLVGRWTAESAVVGVHGTTRVAVIGEHGVTLREARRAAAAAATTGSLAALDRYSTTWAG
                     SFHLVASSGGRVRVQGGVVDLRRVFYAEATPAASHRVSAASARMRAASARVSVASDRAD
                     VLAELVGAGLDERRLALELLTLGVPHPLSGSPQWRGVHALRGGHFLGLEADGQARPSRW
                     WSPPDPDVPLAEGAGRLREVLTAAVDVRTRGRDLVTTDLGGLDSTAVCCAAARGEAEVV
                     AYTAALHDELGDDVHWARQTVQALGSVEHHVVPAQDTALTFDGIDTLQDILDTPSMLTV
                     DRNRRMHLLKRAAARGSGLHLTGLGGDELLAGTPARLHALIAAHPLRALRDVRGYAAKY
                     QWPRHKVLGQLLDRRSYRSWLARVARDLTGPAAAADEPLLDWSVPPRMPPWATSEAVAA
                     ARELLLTCLPDAEPRGRGHGEHRELAAMDGISQWTRHIGQMAAPLGVTVAAPYYDDRVI
                     EACLAVRTPDRITPWRYKPLIVEATRGIVPEAVRTRGTKANATFEEETGCGVTAAGCWR
                     CARNPGWAGSA"
     aSDomain        11925..12173
                     /aSDomain="Stand_Alone_Lasso_RRE"
                     /aSTool="RREfinder"
                     /database="RREFam.hmm"
                     /description="Stand-alone RRE protein in a lasso peptide
                     cluster"
                     /detection="hmmscan"
                     /domain_id="rrefinder_KGS77_RS00215_Stand_Alone_Lasso_RRE.1
                     "
                     /evalue="1.20E-23"
                     /identifier="RREFam002.1"
                     /label="KGS77_RS00215"
                     /locus_tag="KGS77_RS00215"
                     /protein_end="83"
                     /protein_start="0"
                     /score="74.0"
                     /tool="antismash"
                     /translation="MYALKPGVLLTETEYGMALLDQKSAEYWTLNPTAAVVLQTLLDGR
                     GIDQAVEALTRDYEGVETDLATQDVIRIIDDLRSAGLL"
     gene            11925..12182
                     /locus_tag="KGS77_RS00215"
                     /old_locus_tag="KGS77_00220"
     CDS             11925..12182
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lassopeptide: Stand_Alone_Lasso_RRE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF05402"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003986678.1"
                     /locus_tag="KGS77_RS00215"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KGS77_00220"
                     /product="lasso peptide biosynthesis PqqD family chaperone"
                     /protein_id="WP_242577872.1"
                     /sec_met_domain="Stand_Alone_Lasso_RRE (E-value: 2.8e-21,
                     bitscore: 74.0, seeds: 25, tool: rule-based-clusters)"
                     /sec_met_domain="PF05402 (E-value: 9.2e-14, bitscore: 50.1,
                     seeds: 461, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MYALKPGVLLTETEYGMALLDQKSAEYWTLNPTAAVVLQTLLDGR
                     GIDQAVEALTRDYEGVETDLATQDVIRIIDDLRSAGLLAP"
     gene            12227..12643
                     /locus_tag="KGS77_RS00220"
                     /old_locus_tag="KGS77_00225"
     CDS             12227..12643
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lassopeptide: PF13471"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003986677.1"
                     /locus_tag="KGS77_RS00220"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KGS77_00225"
                     /product="lasso peptide biosynthesis B2 protein"
                     /protein_id="WP_242577880.1"
                     /sec_met_domain="PF13471 (E-value: 1e-23, bitscore: 82.2,
                     seeds: 84, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSTPETLPYRPRSIPLARRLTARMAVGCAHVLATLPPGRIRVVLR
                     LLRYGAKPATLAEAARARQTVLAVSLAAGGSKGCLPRSLATVLLCRLHGQWPAWCVGVR
                     ARPPFAAHAWVEAEGELVGENVPASYFQRFFAVE"
     gene            12648..14587
                     /locus_tag="KGS77_RS00225"
                     /old_locus_tag="KGS77_00230"
                     /pseudo=""
     CDS             12648..14587
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1288: ABC
                     transporter related protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003986676.1"
                     /locus_tag="KGS77_RS00225"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /old_locus_tag="KGS77_00230"
                     /product="ABC transporter ATP-binding protein"
                     /pseudo=""
                     /transl_table=11
                     /translation="MTSAPPTATRPAGGPAHPPEQPASPAGPAPAWFGLRALAGHLRPQ
                     RVRMLAGVALGLLGSLLGLAQPMAAKQVMDLIGHGQPSTGPLVILSTLVVAGGLLAGLG
                     HYVLDCSAESVVCTVRRRLTHLLPRLRVPVIEHSEPGDLIARVTSDTALLRRTAPQALS
                     AAVTGTVITVATVVMMGLLDAVLLGVTLIVIAFVGLVVMVVTPHIGRATRHTQEAVGRM
                     GAGLERTLGALRTVKAAGAEQRETAALHRAAEYARRTGVRAAAWEAVSATLSAVVLQVC
                     FLVVLGVGGARVTSGSIGVSTLVAFLLYLFALAPRIGQLVEGVGQLQIGAAAAGRIREA
                     EALEAEEVEGEEGQGEEGQGEEVEIAEGRSDEAGAAPPGPPGSHERHRHPATVTFQRVH
                     FTYRPGHPRSTATSPSPYPPGARPRSSDRPARASPPSSPSSSVSTSRTPAAYCSTAGTY
                     AAGRSPSSVPPSATSNRTRPSSPEPCATT"
     gene            14973..15281
                     /locus_tag="KGS77_RS00230"
                     /old_locus_tag="KGS77_00235"
     CDS             14973..15281
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004940724.1"
                     /locus_tag="KGS77_RS00230"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KGS77_00235"
                     /product="hypothetical protein"
                     /protein_id="WP_242577882.1"
                     /transl_table=11
                     /translation="MEDERLSRPDLVADALSRFERAFGQPGRFLNAPEVWQPGLEIEDA
                     RDDLEEVMRHLPRGARIDLGRLITRIDAEFERRTLPDPGRQPECTAGCWWWWRIRER"
     gene            15405..15689
                     /locus_tag="KGS77_RS00235"
                     /old_locus_tag="KGS77_00240"
     CDS             15405..15689
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="KGS77_RS00235"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="KGS77_00240"
                     /product="hypothetical protein"
                     /protein_id="WP_242577884.1"
                     /transl_table=11
                     /translation="MSLAELRRSVDLLLRHVEVAAAGDAVVLERDYFWSVPADESYDVS
                     KEPSDLTIGQVSESWQHVKDLLADQDRAVGHHLVWLADVLRAIGQDMSA"
     gene            complement(15799..16608)
                     /locus_tag="KGS77_RS00240"
                     /old_locus_tag="KGS77_00245"
     CDS             complement(15799..16608)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="KGS77_RS00240"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="KGS77_00245"
                     /product="hypothetical protein"
                     /protein_id="WP_242577886.1"
                     /transl_table=11
                     /translation="MRPTPARILRRRLAQLDAAADPTTGTDAGLRHFTSVMTGWTEPEV
                     TALAGGPAILAPSEVEEADEMADGCLLLGRLARDHRCLVRGPLDRMRQHWIGTSPHELV
                     PHRRPALDRERFTAPGADPGPPSTKPFHQGLYTSTARRDGPGMWRMYLERGTSLHPRPW
                     QTWELPVTDPAADVLDIGGASDWAAFVVRYPLVRGDDVYPDWAQAARDFAGVHMTLRAI
                     VAAQGFRIPVAGGLAAAPYWDLESVLWLRWCFSTPRLVEITPPESRP"
     gene            complement(16671..17189)
                     /locus_tag="KGS77_RS00245"
                     /old_locus_tag="KGS77_00250"
     CDS             complement(16671..17189)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="KGS77_RS00245"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="KGS77_00250"
                     /product="hypothetical protein"
                     /protein_id="WP_242577888.1"
                     /transl_table=11
                     /translation="MRTWRTAVAAVSMAALAFVGGTCPAAAGEATGDPSASAAVPDGAG
                     AHSGSVDAGRPGADADPSAVIRCEGQVQRPHNSTHVPGTVNVVVTVMCTAPVPEITTRA
                     ALYRNGHLVNQSELRTQRATRSAQNNAAVRCSPGNYRGWMYFKVVFPPGYRPPVSSGNG
                     FGQEVGLAC"
     misc_feature    17371..17384
                     /note="TFBS match to ArgR, Regulator of arginine
                     biosynthesis genes, confidence: weak, score: 16.85"
                     /tool="antismash"
     gene            17742..18188
                     /locus_tag="KGS77_RS00250"
     CDS             17742..18188
                     /EC_number="3.1.2.-"
                     /GO_function="GO:0047617 - fatty acyl-CoA hydrolase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF015048.4"
                     /locus_tag="KGS77_RS00250"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="PaaI family thioesterase"
                     /protein_id="WP_242577890.1"
                     /transl_table=11
                     /translation="MPDDVRSDDSQGPPVPSWFSLDAARQVLDASPFAAWWGVGLTEVR
                     PGRATLLLPWREHFLRPGGVMQGACCMMLGDVATWIAMMAQVEQWERAVTLEMKTNFLG
                     AARCDLWCEGWVVKAGRRSVFCQAATRDAEGRQVAHHTVTYLLP"
     gene            complement(18173..19258)
                     /locus_tag="KGS77_RS00255"
                     /old_locus_tag="KGS77_00260"
     CDS             complement(18173..19258)
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /GO_process="GO:0006520 - amino acid metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009081484.1"
                     /locus_tag="KGS77_RS00255"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KGS77_00260"
                     /product="Glu/Leu/Phe/Val dehydrogenase dimerization
                     domain-containing protein"
                     /protein_id="WP_242577892.1"
                     /transl_table=11
                     /translation="MGVFDRFAGHEQVLFTADQASGLRCVIAIHSTALGPSLGGTRFVP
                     YATEEAALADALRLSRAMTYKAACAGLDIGGGKGIVIGDPSRMKTEAVLRGYGQAVESL
                     GGRYIAACDMGTTPADLAVVGRETRWARGTEPVEGGSGDSARLTAYGVYLGIKASLRWQ
                     FGDDRLDGCRIAIDGVGKVGLRLAGRLYEQGAQLYVADIDTAAAEAAATAYGAVITPPE
                     KLYGLEADVLSPNSVGGVLNEATLPELRCRVIAGAANNQLATEDIAGRLAERGILYAPD
                     FVVNAGGLIQVVDELHEGGPVEERARACAETIPERLTQIFARAADDGVSTERAAVLLAE
                     ERLRAVGRLRSFWSPWRHGSR"
     gene            complement(19406..20206)
                     /locus_tag="KGS77_RS00260"
                     /old_locus_tag="KGS77_00265"
     CDS             complement(19406..20206)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018092611.1"
                     /locus_tag="KGS77_RS00260"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KGS77_00265"
                     /product="hypothetical protein"
                     /protein_id="WP_242577894.1"
                     /transl_table=11
                     /translation="MISVDSMVDCVKSHRLYAHPMYDHWAETTPPVETTAALFHQVQKF
                     CASTRPGLAFPPALREMGWNQQADLIQEIVESESGHGAELATMAGHIVNRIAGEPYFSD
                     VFDRNTVEPGLKEHSDRILGALPGYDPVKGLTAQAAAAISVFERRTESERTTTIRNLGT
                     SLALEIISNQSIIPGEKRALVDSGHYGVTMEEPEMHYLAEHWGECGAEQLHERNVIEAV
                     GSVIDRQTAPELEKGMTDFLESLSALWDVIDAALLKSGVDRVHG"
     misc_feature    complement(20181..20196)
                     /note="TFBS match to LexA_variant_1, Repressor of DNA
                     damage response, confidence: weak, score: 19.85"
                     /tool="antismash"
     misc_feature    20193..20206
                     /note="TFBS match to ANR, Anaerobic transcriptional
                     regulator, confidence: weak, score: 19.7"
                     /tool="antismash"
     gene            complement(20232..20966)
                     /locus_tag="KGS77_RS00265"
                     /old_locus_tag="KGS77_00270"
     CDS             complement(20232..20966)
                     /GO_process="GO:0010124 - phenylacetate catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018092612.1"
                     /locus_tag="KGS77_RS00265"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KGS77_00270"
                     /product="Phenylacetic acid catabolic protein"
                     /protein_id="WP_242577895.1"
                     /transl_table=11
                     /translation="MAGTFSDKIDRDDLAKMPDEYRDILVHQMLANGEGELSAGDTYVD
                     SFYPLAPDADERTKCLKFAMEEIDHYRRFAKLLKQLDIDIGYMVGQQKKERRYFPAESM
                     TTPFTTWEERAAFSFLCELEGHCQINEMAHSTYEPLVPEAAAILKEEAGHFGHGKLLMR
                     RAHDDPETRARAQEALNRFYPMALDMFGRSDSKRAARAVHWGLRRHTNGELRELYQQQI
                     RGHIESLGYDMPPDDPSLRRYH"
     gene            complement(21248..21931)
                     /locus_tag="KGS77_RS00270"
                     /old_locus_tag="KGS77_00275"
     CDS             complement(21248..21931)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1016: LuxR family
                     DNA-binding response regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: protein motif:HMM:NF012301.4"
                     /locus_tag="KGS77_RS00270"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KGS77_00275"
                     /product="response regulator transcription factor"
                     /protein_id="WP_242577897.1"
                     /transl_table=11
                     /translation="MTVRLLLADDQAVTRAGFRVLLSESPGLSVIGEADGPDEVLDTAG
                     RLKPDVVLLNLRALNRTQLALLTKRLRCPGCAPDSAVVIVKAPENSVGFAEALAAGGSG
                     CVAQDAARQALVNAVMLVSEGGVVCLPGEELRALLEGPLSCCADDPVSWPSSVASLTER
                     EIAVLALLGRGLTNSEMAAELHLAVTTVKKHLAGALQKIDEPSRVRAALFASRHRLDVL
                     HTARG"
ORIGIN
        1 cgcgcggtcc actgcggcca ggttcccgtc tcggccagca cctgccgcat cgccatccag
       61 tgacccgcct tgacctcctg caccgccgga tacagggcgg tgtcacggcc cgccgggtga
      121 tagctgacca tcagcgctcc ccccaggcgg cctggatgcc ggtggggtgc agcgggccct
      181 gcgcaatgcc ctcgccgacg ccatgtccgg ctgaagaggc agcaccgcga acggcagcac
      241 catggcggag ctgatggtgc cgctcggccg aagccgggcc ggtgctgacc gcgccggcag
      301 ccaccggtct gcagcacagc gggatccggc cggccggcaa gccgcgccca ggcggtatcc
      361 gcgccttcac ccggtgaccg ccgggcccgg caggcctgcc gggagttggg atgcgtttcc
      421 gtgacgggcc gtacggcatc gcacggtgag gggcgcggcg ggccgtgccc gggccgccgc
      481 gggcagcacc gccggacggt ggttgctggg gacacgacac caagtggtgc gcagacgcgg
      541 ccatggatgc ggaagtcctc tgggcagaag gggtgcgtgg tctcggcggg gacaccggac
      601 gcggggacgc gggcggagcc gacgcgcaag cagagcccct gcgcaggctg tcccacgagc
      661 gcccaagccg ccggggcgcg ggcatgacag ctacctaagc gccccgggcg gcgcagggcc
      721 agagccgcgc ggggttgttc ggttgtagca gcgttggcag taaaaccccg tacgcaaacc
      781 ctgctcgccg gcgccggcgg cgatatcgac cgcctccgcg ggtgaatccg cagccgtcga
      841 agtggcggac gccagttccc tcgccccacg cggggtcggc gcactgctcc gaaccgggag
      901 ttcacgtgca gccaagcggc cagttccgtc ctcgcgcggt caggccgtac ccgccatgtc
      961 ccgggcccgg ggacgtgacc tggccaccgc caccgcggcc gacgggtccg ccgcctacgc
     1021 gctcaacgcc ggccacgcgc aacggctgat gccggccgcc ctgccgcatc tgcgggcggc
     1081 cggcggcgaa tcggccgtcc tgaactcgtt catcagcagg tggaaaccca gcccccaggc
     1141 caagtacggt gcagccaaag ccgcgctgct cagcacggcc ggaaccctcg ccaacgacct
     1201 cggccccggc cacgtccggg tcaacgtcta ttccccgggt cggtgctcat tcccggccgc
     1261 cgctgggccc ggctgcagga acaggaacct caggcgttcg cccgcttcac cgcacagctc
     1321 ccgggcgggt agctggtcac accgcaggag gacgcctgca ccgtcgtgtc gcccgcaccg
     1381 tcgtattcct gctctcgcct tggtccagcg gtgtctccgg tgcccgcatc cccgtcgacc
     1441 gggcacgaaa cgccccacac cggacggcta ctgaccgctc aggccgtctg cagcaccggc
     1501 tgcgccgccc gcaagaagcc ctgcaccgcc ggctctttgt tgaacacgct cacccgctgg
     1561 ccgaaatcgc gcagggcctg caccgaccgc tgactgcgga ccaactccag gcctttgagc
     1621 gcggcgtgcg cacaggccag cgcctcgtcc agccgctgct gctgaaggca ggcggtggcc
     1681 agcatcgcct ggctgatcgc ctgccggcgc cgccgatcgg tgttcgcccg caccgaggcg
     1741 tccgccatct gctcggcctg cccggcctcg cccacatccc gaaagacgaa ggcggcctcc
     1801 gcctcccagt agtggcggtc gaggtagcgc acccacggcg actcctgctc cgcaccccgg
     1861 ctccgtccca aggcggcctc cgcatcctcc agcgcccgca gagcctgctt cgggcggctg
     1921 ctcgcggcac agccgcgcgc caccatcatg tgcagccgca tcagccccag cgggctgccc
     1981 gcgtgccgtg ccgtctgcag ccccgcccgg gccagatgca ccccgtcctg cggatggccc
     2041 aggctggtgg acagatgtga cagccctgcc aggatctggc cggccagcac cagatcccca
     2101 ccctcctggc acaaccgcag cgcctggatc atgtaccgct gcgcgagacc gtactcgccg
     2161 ctgtcgtagc tgctccagcc ggccagagcc ccgagccggg ccgccgcggt gaacagcggg
     2221 ccacgctctt cggcgctcat cccccggcgc agcatcggca ggacctcatg gtgcaggtag
     2281 aacaggatgc tcgaacgcac ctcctggcca ccgaaggtgt tgtccacctg gtcgaaggcg
     2341 gtgatcatcg cctgcaccac cgccacccgg ccccggccga gaccgcggcc ggcgccgggg
     2401 cctccgactg ctcccacgcc cacagcagcc agcctcgctg cggcgcgagc agcgcactgc
     2461 tgacgaacgg caccagcccc agcacgtccc gacagccgac atcgtccgca gtgaggtcgg
     2521 acagcgtctg gagcacctcg cccacgtcct cgccgtaccg cagggaacgg atcaccaccg
     2581 gtggcccctg ctgggcagcg aacccgatgt cacacggctg caccacccgg cccagcgcct
     2641 ccgtcagcac ccccgccacc agccatatcg tctccgtacg agggggccgt ccgccgatcc
     2701 accgggacac cgacgccttg tcatagcgcg tgccccgccc ctgacggcgt gcaagggcat
     2761 tcacccgcgc agcgaacgac tgatagctgc agcccgtttc ccgcagtgtg gccgccaacg
     2821 ctgcgttcct gccactctca ggagcctgtc cgttggccgt catggctccc atcacactcc
     2881 gtgccgtacg gctggccgct tctgctgagt catccacgtc cgagacacac atccgcccgc
     2941 gacggcagag cagcgggcgg cgccaccagc agacgccgaa gtcccctacc gtgtcgccgt
     3001 gttgcgtacc gcgatcacta tgctcaccgt gtgacctcag gtgcaaccga gtcgggagtc
     3061 actttcagac gattcatgat gcccctcgac accacaccgt cggtacgccg tcagcctgtc
     3121 gctgaggcgc ctcagggctc cagggctcca ggacccgcgg tacctgagcc gcccggccgg
     3181 tgatctccgg gtcgatatcg accgtcgtga cctcgccgcc ctcgccgacc agctccgcca
     3241 gatatgccgc gctcaggccc ccggagccga tctccagcac ccgcatccct ggcctgatct
     3301 gggcctgctc cagcatgaac gcctgggtct gcggcgcgct caccgaactc gcggccaccc
     3361 ctcgcttgtt ccgcttgatg accagggcgt tgcaggggcg gtaagcgtcc tccaggctgg
     3421 ccccgggagt gaaccggtgc cgctcgacct tacgcatcac cgcctcgacg ttcttcgaga
     3481 cgatctcgcc acgctcgacg agctggtgcg gttctttctg agtgagggac ggggaagcga
     3541 gacgaatacc tgtttcagca gcaggccggg cacgcgttac cgtgcggcaa gatcagagga
     3601 gggactgtgg cactggtcag taagggctcg cgccgcattg tcgtggacgg ggagacctac
     3661 cggtggcggc tgcgccgcag gcccacttac agccagggac tgtgctggac gccctgcacc
     3721 tacgccgtcg aacacgccga tcgcccggga acgtcactgg tgatcaccac cgaccagccg
     3781 cactccagca actggatcgg cagaaccggc accccgattc ttccctccga cgtaacggat
     3841 cacattcgca ccgcgctcgc gcgaggctgg gccccggatc gcccgggttc tcccttcgag
     3901 ctggacctct cccacgggtt cgtctccggg tacggctctc tctgaaggca gtgactgtca
     3961 ggtcgtgaga gcgtatcggt gctggccggc tggatagaga cgctgatgct cggcggcgcg
     4021 gtagtgctcc cagcaggcgt cacggtcctc attggcggcg acggtacgga gttccaaaac
     4081 cgcctcggca ccgtcaaggc cccagcgagc tccgccgatg tcgaggcggt cggcgacgag
     4141 gtggcgtgcg gctccttcga ggatcccggt ggcgatgggc cagccggcct ggagggctcg
     4201 gtcgtagtgg aggaacccgc gaagagactc atggtgtagc ggattttctc tcaggagcgg
     4261 tgcagactca cggaagtgat ggccgccggc actgggtggt cgccctcggc ccctggcgct
     4321 gagagcggca tcatggttgc ggtgaagtgg cggttgctcc gtttcggggg gtcgcctcgc
     4381 caggttctgc gtcaatgcgg caaaatgcgc ggcgttcatt cgcccatgtc cccagcctct
     4441 gagcggattc ggccacggca ctgtcggctc ggcggtagcg tggcatctca gcccaaaggc
     4501 gattgtccgg aaacttcgtc agctacctgg tctgtgtggc cagcggcgcc cacttcaggg
     4561 tgaagacgga cccggtccga aaagcgagcg gatcgacctc caggcgccct tcgaccgcct
     4621 cgggcccggt gcgcgccacc acgagggtcg gtttgcagac gtccgtcatc accatcgccg
     4681 ggtgatctac gtcgagccat ttgaacaacg gccgggtcag gtcgggcact gggtcgacga
     4741 cagtcgtgaa cagcgtgggg atctcgactc ggatgtcgcg gaccgtccac atcagccggt
     4801 ctccccacga ctcgcttgcc gggtcctcga cgggatcgcc tggggcgtcg tcccactgcg
     4861 gctcaggggt gtcctgactc agccgttcga agcgctcgat gacgatgagg cgtggttttc
     4921 ggcccgcgat gagtctttgg gcgctgaggt tgatatgcgc tgcggtcggc gtgggagtca
     4981 tgtcgatgaa aagtgacgca ggccgggtgg caggcgggta accggtgaag agaaccacgg
     5041 gggtgccagc tcgcgcggca tggaccgcga tgtcccggcc gaccttggct tcccggctac
     5101 cgcgctgtgc gacgatgccg gccttgtggc ggaagctgag atcggcgagt ggcgtcagac
     5161 cgggccacgg ggtgggcacc gtctctgctg cctcgcgtac gtcatcgacg gtttcggtca
     5221 tcacgtctcc ggttctggag ctgcgtcctt gcgaatgtac cgtgcagcga acgtttttcg
     5281 aggctggtcc gttgtgccat ctccgcgtcg tcccggggca gtggccctgg gcccgttcac
     5341 cgtgtggcgc aggcggggca ggcggcctgt tcggggttgt ggcggcggcg tcggcagatg
     5401 caccagggcc agtcgaggca ttcggggcac tgggtgtgcg ggggtgtgac gggccggccg
     5461 caggttcctc cgcggccggt gcactccggg atcgggggcc ggtagctgat ggcgtcggcg
     5521 agcgagcgcg ccgacgccgg ctggccttcg gcttcgtcgt cttcctcggc ctcgtcgcgc
     5581 cggggggcga gcagccgtcc gccgcggcag acggtgcacg gttcgtcgtc gcggtcgggt
     5641 cgctccggtg gggccgggag ccagccgtct tcacagtggc cgtggcaggc ggtgggggcc
     5701 agcagccaca ccgcgacgtc gtcgggtccg tagccgtcgc ggtgcccgtc ggccttgcgc
     5761 ttaagggggc ggcttgacca gctcttccac cagcggcgct cgatgcgggc ggcgagccgg
     5821 gccggggtgt gccgccgcag ttcgtcgtgg acgaggtcga cgacggcggg cgggacgccg
     5881 ccgccgcagg ccaggacgag cttgtcgggc agcgcggcca gcaccgcacg caaggggtcc
     5941 ttcgcgctcg gcgcggtctg gcacgcgtcg cactggtccc ggtcccagga gcgcgggaag
     6001 tagatgcgcg cccacttgcg gcggcggtcc ttgcgctttt cgggctcgac gcgcgtgatg
     6061 ccggccgcgt actcggggcg ctcgggcaac ggcccggagc aggtgcggca gcggtcccgg
     6121 caggtgcggc agcgctcgcc gttggaggtc agagcctggc aggaggggca ctcgcgtcgg
     6181 catacggagc acaggtggtc gtcggggtgg ggctgagcca gccagcggtg ctcgccctgg
     6241 cagcgcacgc agcgccgggt gtcggtctct tcccgatggg tgggcaggac gggccggccc
     6301 gggcactggt cgcagcggat gacggcccgg tcagcggacg ggcgcaaaaa cgtgctcatg
     6361 cgatgctccc ggcgtcgggg tgggcgagtt gatcagcgta gcggtggttt cccggcgcag
     6421 cgtgccgccg tgcccgctgg cggcgtggct acccgcgggc tgtaccggcc gcggtgatga
     6481 cccgtaccgg aatcgatgcc gtccgcgctg cgtccacgac acgtgtgagg cgcgccgggt
     6541 ccggcattgc gagctgtcca ctctgcgacg acgcggtcgg cccggctgcg cgcggtgtgc
     6601 ccgaagcaca gcgccgaccg agggtgccgg gctgcgacct ggaacggaag gtgcggcggg
     6661 acgtacttct cgggatctcc gtggtcgtgg gcattcgccg ctgtggcggc gagggaggcg
     6721 agggtgtcct gcacgtaccg ggtgtcgtgg atccagacag ggtctcccgg cagcacacag
     6781 ggggagtccg ctcgttgctt cgtcacctgc tcactgcccg ctcaccctgc ccgtacggac
     6841 caccggtgaa ctacgggtcg ccggaatgcg tgccgcagac ccggccgcgc agcagctcct
     6901 caacccagtc ctacagccag gttcccagcg cccaccgcca gcacgggcgg ccctcgccag
     6961 gggcatctgc tcgatgcgta accgagcgga gggccggctt ccgggtggag ccggcccggt
     7021 gtgcgttcag atgtgcttgc gtggggtgac gatggggaac ttcgggtcgg gcagggtcag
     7081 ggtgccgaag acggcgtccg tcgccgcctg ggccttggcg ccctccaggg tgatcttctt
     7141 gtcctgcacc gcgttgttga agttgtcctt gaagccgggg gactcggcca gttcgtcgag
     7201 cgcctggcgg ctcagcctga tggtcgccgc cggagcctgg acgaagcggt caccgccttc
     7261 gacgaagacc agcacaccgt tgcggagcgt cgtggtgcac ttctggccgg tctcgacgcc
     7321 gttctcgtcg gtgaagaccc agttgagtgc gatcggctcg cggtactgct cggcggccgt
     7381 cggcccgtcc acgctccggg cgagcgcgga gaagtactgt tccaaagtgg tgctgcggat
     7441 caggtcagcg gacgtctgag aggtgatcag cggctgcggg ccgcccagga cctcctgcgc
     7501 gccggtgagg taggcattgc gccaggtgcc gttctcgctg ccgtagccga gctgggtgaa
     7561 gaccttggac tggagttccc tggcccgcgt gacctgcggc tcggcgagcg ggctgcctgt
     7621 ctcggcggcg gatgcgaaga tcacgtggtt gaggagttcg gccgcccagc ggaacccgtc
     7681 cggggtgtcg cggtcatagg cgcgctgggc cgcatcgacg acggcttccg cgccgcccat
     7741 cgcctccacg taggccgcgc ccgcctggac cggcggcagc tcccacaggt gggccgggtt
     7801 gccgtcgtac cagcccatgt aacgctggta gaccgccttg aagttgtggc tcaccgagcc
     7861 gtagtaaccc cggtcgtacc agtgatcggc caggctcggc gggagggtct ggagctgttc
     7921 ggagatctcg gggccggtgt aaccggcgtt gatcatccgc agcgcctggt cgttgagata
     7981 gccgtacatg tcgcgctgct tgttgaggaa ctcaaggatc cgctcattgc ccggcccctc
     8041 ctcccctccc tcgtcccgta cttcgttcca catcggccag tggtgggagg cgaacaggac
     8101 gtcggtctcc ttgccgaagc tctggatcgc ctcggtgagg tacttcgacc aggcgtgcgc
     8161 gtcccgcacc tgcgcgccac gcaggctgag gatgttgtgc atggtgtgcg tggcgttctc
     8221 cgcgatgcac agcgtcctgg cgtccgggaa gtagatgttc atctccgccg gcgcctcggt
     8281 gcccggtgtg agctggaaga ccagtgggaa cccgaacccg tcgaacacgt acagccccgg
     8341 ccgccacggg atcacgtacg agggctgcca gttccccttc gcaaccggct ggtgggccgg
     8401 cccgccgatg tagacggtcg gcgggacgag agtcacctcg cccgtggaga tcgtcaggcc
     8461 cagccccgaa ccgacctgcc ctgcggggcc cttgtccatc tgtgccgcat acatgtactg
     8521 cgcgcgccgt gccatggccg gtccggcgta gatgttctcg ctgaccgcgt gctccaggaa
     8581 cccgtcgggc gcgacgacgg gcacgcccgg ctccaggggg tccccctgtt cgctgaagat
     8641 gccgcgggcg ccgccgaagt ggtcgacgtg gcagtgggtg tagatcagcc ccttgaccgg
     8701 ccgcagttcc ttggtgagtt ccgtcttgtc gcggaacagc ttcaaggcgg cctgcgcggt
     8761 ctcgtaggag gccagcgggt cgatgatgta caggcccgag tcgtgctcga tgatcgtcat
     8821 gttggacagg tcgtagccgc gcacctggta gatgcggtac tgggaacagg aggtgacctg
     8881 gaacagcccg gcgacggcgg tcagctcgcc ctgccggtgc aggctgccgt tgaccgacgg
     8941 catctccata cgtgtttccg ggttgaggaa gtcgtaggcg gtgaagtccc agaccacctt
     9001 ctccgggtcc ttgcgggaca tgatgacggg gacgtcgggc ggggcgatct ggaacctgat
     9061 ggcgtcggcg aagtccctgc cgtccttctc atcggccgcg ttggcagctt cggcggcctt
     9121 gcggttcccc gcggcgaccg cgaccgaagg ttcgacgggt tggaggtacg tggagctctc
     9181 aggcatggtg caacatcctc cccatgaggg cgcgacagcg ttcgacggcg ggcggcacgc
     9241 tatgtgcgca cgcaatcaca ggcaagggtg tgatcgagcc gttggccggg gacgcccgcg
     9301 gcggacagcc gtcgtgcaga ggaagcaagc agctcaaaca cgctttcttc cgctccgcgt
     9361 tcgctgccct ggccgcctcg gtctcccggg cctaccacgg aaagaagact gcccgggcga
     9421 ggcgccggac tgcgcgccac cggcctgacc gtacggatca ccgctctctg ccctcaccga
     9481 acggcggcgt ggcattggat cggtgttctc aaacccgtct gggtcaccac tgtggagcgc
     9541 gtgacatcac accgcgccgc cgcgacagaa acacacgccc ccggcgtact acacgtcgcc
     9601 ggggacgaat cattgtgatg atgctctgag cactcttacg gttaccgcgc ggcatcaacc
     9661 gctcgcggga gcgaagacgc aaatgctttc gcatgtcgtc gatccggtcc cgtgatccgc
     9721 gttgtccccc cagggaaaag gagtgcgacc atgacgtacg agcgccccac cctcaccaag
     9781 gtcggcggct tccgcaaggt gacgggcgtc aagaacaccg gtcccaagga cgttctcggc
     9841 ggcaagcagc tcctgtgacg cgaccggtgc ggagccgttg agcggttccg caccgtaccc
     9901 cgggccgggc cggccccgcg ccggcccggt ctgcggtggg ccgagccgtc cgccggcgcc
     9961 ccgcccgctc ccgacgtcgc agcgaccgga ggccgtagcc gtggaagagt ccctgtcctt
    10021 gtcggccctg cccggctggt tcgtcgtcct gcccgacacc gacgcggtcg ccacggtcgc
    10081 ggcgaaggcg ctttcccacg cgtcgcacag cctgccccac gcgtccggca ggccctggct
    10141 ggtgggccgg tggacagcgg agtcggccgt cgtgggagtg cacggcacga cccgcgtcgc
    10201 cgtgatcggg gagcatggcg tcaccctccg ggaagcccgg cgcgccgccg cggcggcagc
    10261 caccaccggg tcgcttgcgg cgctggaccg gtacagcacc acgtgggcgg gcagcttcca
    10321 tctcgtggcg agttcaggtg gacgggtccg ggtgcagggc ggagtcgtcg acctgcggcg
    10381 ggtgttctac gccgaggcca cgcctgccgc gtcccaccgg gtcagcgccg cgtccgcccg
    10441 gatgagggcc gcgtccgccc gggtgagcgt cgcgtccgac cgggccgacg tgctggccga
    10501 gctggtcggt gcggggctgg acgaacgccg gctcgccctg gagctgctca ccttgggcgt
    10561 accgcacccg ctgtcgggat caccgcagtg gcggggcgtc cacgccctgc gcggcggcca
    10621 cttcctgggt ctggaggccg acgggcaagc acggccgagc cggtggtggt caccgcccga
    10681 ccccgatgtc ccgctggcgg agggggccgg gcgcctgcgc gaggtgctga ccgccgccgt
    10741 cgatgtgcgt acgcgagggc gcgacctggt gacgacggac ctgggcggtc tggactccac
    10801 ggccgtgtgc tgcgccgcgg cacgcgggga ggcggaggtc gtcgcgtaca ccgccgccct
    10861 ccatgacgaa ctcggcgacg atgtgcactg ggcgcggcag accgtccagg ccctgggatc
    10921 ggtcgagcac cacgtcgtac ccgcccagga cacggccctg acgtttgacg gtatcgatac
    10981 gctccaggac atcctggata cgcccagcat gctcacggtc gaccggaacc gccgtatgca
    11041 cctccttaag cgggcagcgg cccgggggtc cggactgcat ctgaccgggc tgggaggcga
    11101 cgaactcctg gccggaacgc ctgcccggct gcacgccctg atagccgctc accccttgcg
    11161 cgctctgcgg gacgtgcgcg ggtacgcggc caagtaccag tggccccggc acaaggtgct
    11221 gggccagctc ctggaccgcc gctcctacag gtcctggctc gcccgcgtcg cccgtgacct
    11281 gaccgggccg gcagccgccg cggacgagcc gctgctcgac tggtccgtac cgccccggat
    11341 gccgccctgg gccacctccg aggccgtcgc tgcggcgcgc gagctgctgc tcacctgcct
    11401 gccggacgcc gagccgcggg gcaggggcca tggcgaacac cgcgaactgg ccgccatgga
    11461 cggcatctcc cagtggaccc ggcacatcgg gcagatggct gctcctctgg gggtcaccgt
    11521 ggcggccccg tactacgacg atcgcgtcat cgaagcgtgt ctcgcggtgc ggacaccgga
    11581 ccggatcacc ccctggcggt acaaaccgct gatcgtcgag gccacgcggg gcatcgtgcc
    11641 cgaagccgtc cgcacgcgcg gcaccaaggc caacgccacc ttcgaggagg agaccggctg
    11701 cggcgtcacc gcggccggct gctggcgctg tgcgaggaat cccggctggg ccggctcggc
    11761 ctgatcgacg tggacgccct gcgggagtgg tgccgccgcc cgctgtccgc ggagacggag
    11821 agccacctgc tgcacgcgac cgtggcctgt gaggtgtggc tgcgctcccg cgagatgaca
    11881 ccggcacccg cccggcccct gaccgaacag gagaggtgac ggcgatgtac gcgctgaaac
    11941 ccggtgtgct gctgaccgag accgagtacg gcatggcgct gctcgaccag aagagcgccg
    12001 agtactggac cctcaacccc acggcagcgg tcgtcctgca gaccctgctg gacggccgcg
    12061 gcatcgacca ggccgtggag gcactgaccc gggactacga gggcgtcgag accgacctgg
    12121 ccacccaaga cgtcatccgc atcatcgacg acctgcgctc cgcgggcctg ctcgcaccgt
    12181 agccgccgta ccgggcacgc gccccggccc cgggaagagg tacgcgatgt cgacaccgga
    12241 aacactcccc taccgccccc gctccatccc cttggcccgc cgcctcacgg cccggatggc
    12301 ggtgggctgc gcccacgtac tggccacgct gccacccggc cgtatccgcg tcgtcctgcg
    12361 cctgctgcgg tacggggcga agcccgccac gctcgccgag gccgcccgcg cccggcagac
    12421 ggtgctcgcc gtgagcctgg cggccggagg gagcaaggga tgcctgcccc ggtccctggc
    12481 caccgtgctg ctgtgccgcc tccacgggca gtggcccgcc tggtgcgtag gggtccgcgc
    12541 ccgtccgccg ttcgccgcac acgcctgggt ggaagccgag ggggaactcg tcggtgagaa
    12601 cgtaccggcc tcgtacttcc agcgcttctt cgccgtggag tgaggccgtg acctcggcgc
    12661 ccccgaccgc aacccgccct gccggcggcc cggcgcaccc gccggaacag ccggcctccc
    12721 ccgccggccc cgcccctgcg tggttcggcc tgcgggccct ggccggccat ttgcgaccgc
    12781 aacgcgtacg catgctcgcc ggtgtcgcac tcggcctgct cggcagtctc ctggggctgg
    12841 cccagccgat ggcggccaag caggtgatgg acctcatcgg ccacgggcag ccgagcaccg
    12901 gccccctggt catcctcagt acgctggtgg tggccggcgg actgctcgcg ggtcttggcc
    12961 actacgtgct cgactgctcc gccgagtccg tcgtctgcac cgtccggcgc aggctgaccc
    13021 acctccttcc acgcctgcgc gtgccggtga tcgaacacag cgagccgggc gacctgatcg
    13081 cccgcgtcac ctccgacacc gcactgctgc ggcgcaccgc accgcaggcc ctgtcggccg
    13141 cggtcaccgg caccgtgatc actgtggcaa ccgtcgtgat gatggggctg ttggacgccg
    13201 tcctgctcgg cgtcaccctc atcgtgatcg cgttcgtcgg cctcgtcgtc atggtggtga
    13261 ccccgcacat cggccgagcc acccggcaca cgcaggaagc cgtcggccgt atgggagccg
    13321 ggctcgaacg gacgctgggt gccctgcgca ccgtcaaggc ggcgggcgcc gaacagcggg
    13381 agaccgcggc gctgcaccgt gcggccgagt acgcccgccg cacgggtgtc cgcgccgccg
    13441 cgtgggaggc ggtctccgcg accctgtcgg ccgtcgtcct ccaggtctgc ttcctggtcg
    13501 tactcggagt aggcggcgcg cgcgtgactt ccggttccat cggcgtctcc acgctcgtcg
    13561 ccttcctcct ctacctcttc gcactggccc ccaggatcgg tcaactggtg gaaggcgtcg
    13621 ggcagttgca gatcggggca gccgcggccg ggcgtatacg ggaagccgag gcgctggagg
    13681 ccgaggaagt ggagggcgag gaggggcagg gtgaggaggg gcagggtgag gaggtggaga
    13741 tcgcggaagg acgcagcgac gaggcgggcg cggctccacc ggggcctccc ggctcccacg
    13801 aacggcaccg gcaccccgcc accgtgacct tccagcgggt gcacttcacc taccggccag
    13861 gtcacccccg gtccaccgcc acatctcctt cgccgtaccc gccgggggca cgaccgcgat
    13921 cgtcggaccg tccggcgcgg gcaagtccac cgtcttcgcc ctcatcgagc gtttctacga
    13981 gccggacacc ggccgcgtac tgctcgacgg cagggacgta cgccgctggc cgctcgccga
    14041 gctccgtgcc gccatcggct acgtcgaaca ggacccggcc gtcctcgccg gaaccctgcg
    14101 cgacaacctg acgctgggcg cggccgacgc caccgacgag cagatcgccc aggccctgtg
    14161 cctggcccgg ctcgacaccg tgacggaccg cctgccgtac ggtctggaca cccaggtcgg
    14221 ccaccgcggc agccggctct ccggcggcga acggcagcgc gtggcgatcg cccgggccct
    14281 gctccgccgg ccccggctgc tcctcctgga cgaggccacc tctcagctcg acgcggccaa
    14341 cgaggccgct ctgcgcgaga ccatcaccga caccgcacgc cgcaccaccg tcctggtcat
    14401 cgcccaccgc ctgtccaccg tgaccaccgc cgaccgcatc ctggtcatgg aagcgggccg
    14461 gatacgggca cggggaaccc acgccgaact gatggcacac gactccctgt acgccgaact
    14521 ggcaagcacc caactgatcg gctaccgccc gggccacggt ccttcagccc cgattccggg
    14581 agcctgagca gcgcgccgta cagtcacctg atgtgtcgtc ccgcggcgga tgggctcgtc
    14641 ccctctctgc cccaccgtgc ccaggatgcg caggcgtgtg gccggtcggc ttcaatgcgt
    14701 tgcgggtctg gcgccgccga cgcccggttc atgaagaacc tgtcgacggc acgtacgtac
    14761 tcgcaggttc tgctcagcct gacgcgacca tgccactcgg cgtcatcccc ggtccggctc
    14821 gtggcagaat gcccgcatga tactgatccg aaagggcgat gccgcgtagg cgcccgaagg
    14881 ccgtccgtac tgagcgatgg cggccccgta agcatgtgat ggtgcgccga atccgcggtg
    14941 tctccgcccg gacccgggcg gccgttcgtc gcgtggagga cgagcggctg agtcgtccgg
    15001 atcttgttgc cgatgcgttg tcccgtttcg agcgggcgtt cgggcagcca gggcggtttt
    15061 tgaacgcgcc ggaggtctgg cagcccggat tggagatcga ggacgcccgc gatgacctgg
    15121 aggaggtcat gcggcatctc ccgcgcggcg cccggatcga cctcggccga ctgatcaccc
    15181 ggatcgatgc cgagttcgag cgccgcactc tgccagatcc cggccggcag ccggagtgta
    15241 ctgcgggctg ttggtggtgg tggaggattc gggagcgttg agcacgtgag tacggtcgat
    15301 gccggttccg gctaagatcg tgagttatgc ccagttcaga gaagtcagcc gcattcggta
    15361 gggcagataa gcaggctgcc gatgtgactg gtgagcctct gcgcgtgtct ctggctgaac
    15421 tgcgcagatc ggtcgatctg ttgctgcggc acgtcgaagt tgcagcagca ggcgatgccg
    15481 tcgtcctgga acgggactat ttctggtctg ttccagccga tgagtcgtac gacgtttcca
    15541 aggagccgag cgatctgacg atcggacagg tttctgaatc ctggcagcat gtgaaggacc
    15601 tgctcgccga tcaggatcgt gccgtgggtc accacctggt gtggctggca gatgtcctgc
    15661 gggcgatcgg gcaggacatg tccgcatgac cgcatgtccg agcgcctcgc gtggtgggcc
    15721 gtcgcgctgg tcaggatgtc gctgacggct cgcggtggat cccggccggt gagccggccg
    15781 aggccggacc ggctgttgtc acggccggga ttcgggcggg gtgatctcca ccagtcgcgg
    15841 ggtggagaag caccagcgca gccagagcac ggattcgagg tcccagtagg gggccgcggc
    15901 caggccgccc gccaccggga tgcggaagcc ctgggccgcg acgatggcgc gcagggtcat
    15961 gtgcaccccg gcgaagtccc gggcggcctg tgcccagtcg gggtagacgt catcgccacg
    16021 gaccagcgga tagcgtacga cgaaggccgc ccagtcgctt gcgccgccga tgtcgaggac
    16081 gtcggcggcg gggtcggtga ccggcagctc ccaggtctgc cagggccggg gatggagact
    16141 cgttccccgt tcgagataca tccgccacat gcccggtccg tcacgtcgcg ccgtggacgt
    16201 atagagcccc tggtggaagg gcttcgtact ggggggacct ggatccgcgc cgggcgcggt
    16261 gaaccgctcc cggtccaggg cgggccgccg gtgtggcacc agctcgtgcg ggctggtgcc
    16321 gatccagtgc tgtcgcatcc ggtcgagcgg tccccgtacg agacaccggt ggtcccgggc
    16381 aagccggccc agcagcaggc aaccgtcggc catctcgtcc gcctcctcca cctcggaggg
    16441 ggcaaggatg gccggaccgc ccgccagggc cgtcacttcg ggctcggtcc accccgtcat
    16501 gacagaggtg aagtgacgca acccggcgtc cgtaccggtg gtcgggtccg ccgctgcgtc
    16561 gagctgtgcc agtcgtcggc gcaggatcct ggcaggggtg gggcgcacac cgtgatcctt
    16621 ccccggtggc gcccccgcgc aacacggtgt cgccgttccg gcggccgagg tcagcaggcg
    16681 aggccgacct cttggccgaa gccgttgccc gagctgaccg gcggccggta gccgggcggg
    16741 aagacgacct tgaagtacat ccagccccgg tagttgccgg ggctgcacct cacggccgcg
    16801 ttgttctggg cgctgcgcgt ggcccgctgc gtcctgagct ccgactggtt gacgagatgg
    16861 ccgttcctgt acagggccgc gcgggtggtg atctccggca ccggtgccgt gcacatgacc
    16921 gtcacgacga cgttgacggt gccgggcacg tgggtggagt tgtgcgggcg ctgtacttgt
    16981 ccctcgcatc ggatcaccgc ggacgggtcg gcgtccgcac cgggcctgcc ggcgtccacg
    17041 ctgccgctgt gggcaccggc tccatccggt acggcggccg aagcggacgg atctccggtc
    17101 gcttcccccg ccgcggcggg gcaggtgccg ccgacgaacg ccagggctgc catcgatacg
    17161 gcggcgaccg ccgtcctcca tgtacgcata tccgctcctc cctgtgcgtc ttttggcgcg
    17221 tggcaggggc tgtgccggta cggatggcgg ccggtgccgc gttcacgcgg gttcggaagc
    17281 cgcgtgaggc gggcggcttc tctcgctgct ccgcgttacg tgcggagacc acgcacaggc
    17341 cagatccccc gtgcgagcat ccccggcggt ggcatgggca tgcggccctg ctgctatcga
    17401 gcgacacagt ggacatctgt ccggcatcga atcgcagcac cccacaggac gggatgccgg
    17461 cctttacgcc acatggactc acatggaccg aagtgtcgcc ccgccggccc tgctcccccg
    17521 gcgccgcacc gagtcgggct tccaggcgcc tgggcggctc ggctccggcc aggccgctgc
    17581 cgccccacgt gctcgccgag gaaaaggatg aggacgacga cggtggtggt cacgcgggcc
    17641 ggatgtgtcg cgtccggcat gggtgtggtt gttcccgcag cggtgatcgg gccggggctg
    17701 agcaccttga cacccctgga cgcggccggt ctcatggacg ggtgcccgac gacgtgcgca
    17761 gcgacgactc ccaaggcccg ccggttccct cgtggttctc gctcgacgcc gcgcgccagg
    17821 ttctggacgc ctcgccgttc gccgcctggt ggggggtggg cctcaccgag gtgcggccgg
    17881 gccgggcgac gttgctgctg ccctggcggg agcatttcct gcggcccggc ggggtgatgc
    17941 agggcgcgtg ctgcatgatg ctcggcgatg tggcgacatg gatcgcgatg atggcgcagg
    18001 tcgagcagtg ggagcgggcc gtcacgctgg agatgaagac gaacttcctg ggcgctgcgc
    18061 gctgcgacct gtggtgcgag ggctgggtgg tcaaggcggg ccgccgctcg gtgttctgcc
    18121 aggcggccac ccgcgatgcc gaggggcggc aggtggcgca ccatacggtg acctacctgc
    18181 tgccgtgacg ccacggtgac cagaaggagc gcagccgtcc gacggcgcgc agccgctcct
    18241 cggccaggag gaccgcggcg cgttcggtgc tgacgccgtc gtccgcggcc cgtgcgaaga
    18301 tctgcgtcag gcgctcgggg atggtctcgg cacacgcccg cgcccgttcc tccacagggc
    18361 cgccctcatg gagttcgtcg acgacctgga tgaggccgcc cgcgttgacg acgaagtcgg
    18421 gcgcgtacag gatgccgcgt tcggcgagac gtccggcgat gtcctcggtg gcgagctggt
    18481 tgttggcggc cccggcgatg acgcggcagc gcagctcggg gagggtggcc tcgttgagga
    18541 cgccgccgac ggagttgggg ctcagaacgt cggcttcgag cccgtacagc ttctcgggcg
    18601 gggtgatgac cgcgccgtag gcggtggcgg ctgcctcggc cgcggcggtg tcgatgtcgg
    18661 cgacgtacaa ctgcgcaccc tgctcgtaca gccgtccggc gagccgcagg ccgactttgc
    18721 cgacgccgtc gatggcgata cggcacccgt cgagccggtc gtcgccgaac tgccaccgca
    18781 gagacgcctt gatgcccagg tacacgccgt aggcggtcag ccgggcggag tcgcccgagc
    18841 cgccctcgac gggctcggtg ccgcgcgccc agcgggtctc gcggccgacg acggcgaggt
    18901 ccgcgggggt ggtacccatg tcgcaagcgg cgatgtagcg gcctccgagg ctctcgacgg
    18961 cctggccgta gccgcgcagc accgcttcgg tcttcatacg ggaggggtcg ccgatgacga
    19021 tgcctttgcc gccgccgatg tccagacccg cgcacgccgc cttgtaggtc atggcgcgcg
    19081 agagccgcag cgcgtcggcg agggcggcct cctcggtggc gtacggtacg aagcgcgtgc
    19141 cgccgaggga ggggccgagc gctgtcgagt ggatggcgat gacgcagcgc aggccgctgg
    19201 cctggtccgc ggtgaacagc acctgctcgt gtcctgcgaa acggtcgaac actcccatgc
    19261 ggacctccca ccggtctgcg gcctcctcgt ccgggccgga ccgcgtgcgc cgctgccgct
    19321 gcccggcgcg agccgctccg cccgccgcgg cggcagggcc ggccggagcg gcggacggag
    19381 cggcgcctga cgtccgacgc gcgtgtcacc cgtgcacgcg gtcgactccc gacttcagca
    19441 gcgccgcgtc gatgacgtcc cacagcgccg agagggactc caggaagtcc gtcatgccct
    19501 tctccagctc cggggcggtc tgccggtcga tgaccgagcc gacggcctcg atgacattgc
    19561 gctcgtggag ctgttccgcc ccgcactcgc cccagtgctc ggcgaggtag tgcatttcgg
    19621 gttcttccat ggtgacgccg tagtggccgc tgtcgaccag agcgcgcttc tccccgggga
    19681 tgatggactg attggagatg atctccagtg cgagagaggt gccgaggtta cggatcgtgg
    19741 tggtgcgctc cgactcggta cggcgctcga aaacggaaat ggcggctgcc gcctgggcgg
    19801 tgaggccctt taccggatcg tagccgggca gcgcgccgag aatccggtcg gagtgctcct
    19861 tcagccccgg ctcgacggtg ttccggtcga acacatccga gaaatagggt tcacccgcga
    19921 tacggttgac gatgtgtccg gccatggtgg cgagttccgc accgtgcccg gactcgctct
    19981 ccacgatctc ctggatgaga tcggcctgct ggttccagcc catctcgcgg agcgcgggcg
    20041 ggaaggcgag ccccgggcgg gtggacgcgc agaatttctg gacctggtgg aaaagtgccg
    20101 cggtggtctc caccgggggc gtggtctcgg cccagtggtc gtacatcgga tgggcgtaga
    20161 gacgatggga tttgacgcag tcgaccatgc tgtcgaccga gatcattgcg gtacctcctg
    20221 ctgagaatgc gtcagtggta acgacgtagc gacgggtcgt ccggaggcat gtcgtatccg
    20281 aggctctcga tatgaccgcg tatctgctgc tggtagagct cgcgcagctc tccgttggtg
    20341 tgccggcgca gtccccagtg gaccgcgcgc gcggcgcgct tggagtccga gcggccgaac
    20401 atgtccagag ccatgggata gaagcggttc agcgcctcct gggcccgtgc gcgcgtctcg
    20461 gggtcgtcgt gggcgcggcg catgaggagc tttccgtggc cgaagtgtcc ggcctcctcc
    20521 ttgaggatgg cggctgcctc gggcaccagc ggctcgtacg tgctgtgcgc catctcgttg
    20581 atctggcagt ggccttccag ctcgcacagg aagctgaagg cggcgcgttc ctcccaggtg
    20641 gtgaaggggg tggtcatgga ttcggccggg aagtacctgc gctccttctt ctgctggccg
    20701 accatgtagc cgatgtcgat gtcgagctgt ttgaggagtt tggcgaagcg acggtagtgg
    20761 tcgatctcct ccatcgcgaa tttcaggcat ttggtgcgct cgtccgcgtc gggagcgagc
    20821 ggatagaagg agtcgacgta ggtgtcaccc gcgctgagtt ctccctcacc gttcgcgagc
    20881 atctgatgga cgaggatgtc gcggtattcg tcgggcattt tcgccaggtc gtccctgtcg
    20941 attttgtcgc tgaacgtccc tgccatggag ccctcctgcg cacacaggca tccgcactca
    21001 ggcgaaaggg gggccgatcg gcgtcggtcg gcgatcggcg tcggtcgatc gggatcggtc
    21061 gaccgcatca ttcgacgaga atcggtcgac cggaatcgga ggatgggaat cggtggatcg
    21121 gaatcggtca gacgccatcc taggaggatc acctgtgggt gacattgtcc gaacggatac
    21181 tgttcgccag gcgcgttgac ctcggggacc gctcgcgtgg taccgcagca ccgttcctgc
    21241 ggcccggtca gccgcgggcg gtgtgcagta cgtccagacg gtggcgggag gcgaagagcg
    21301 cggcacgtac ccggctcggc tcgtcgatct tctgcagcgc acccgccagg tgcttcttca
    21361 cggtggtcac ggccagatgg agctcggcgg ccatctcgct gttggtcagg ccccggccca
    21421 gcagggccag gacggcgatc tcgcgctcgg tcagcgaggc cacggacgac ggccagctca
    21481 ccgggtcgtc ggcgcagcag gacagcgggc cctccagcag ggcccgcagc tcttcgcccg
    21541 gcagacagac cacgccgccc tccgacacca gcatgacggc gttgaccagc gcctgccggg
    21601 cggcgtcctg ggcgacgcag ccgctgccgc cggccgcgag cgcctcggcg aagccgacgc
    21661 tgttctccgg ggccttgacg atgacgaccg cgctgtccgg cgcacacccc ggacagcgca
    21721 gccgcttggt cagcagcgcg agctgggtac ggttcagcgc gcgcaggttg agcagcacga
    21781 cgtcgggttt gagccgtccg gccgtatcga gcacctcgtc cgggccgtcc gcctcgccga
    21841 tcaccgagag cccgggcgac tccgacagca gcacccggaa gccggctcgt gtgacggctt
    21901 ggtcgtcggc caggagcaga cgcacggtca tagcgccccc cgttggatcc ggccggcctc
    21961 tgggatcgcc actgccggcg gatgcgccca gcctaggacg gctgccaggc ggcgaaccag
    22021 tcgtccggtg ccacctgatg cggaatcggc cgacccgtgc cccggccgtc acggtcgggg
    22081 cctggctcgt accgaaaccg gacggccgcc acggtacgta tcggtatgcg ccctcccacc
    22141 gcccccgtcc cgataccggc ccgactcacg gcccccgctc ctggcccgat cctggcccga
    22201 ctcacggccg gatgacgggt gcggtggcgg cagacggcca aggcgcccgc ccggccgccg
    22261 gtgcggtgac gaattccacg gccgccacct gctcccgcga acggcggtcc agcaagacca
    22321 ccgatgccgc ctcccgtacg aggtcaggga ggggagccgt cggcgcggca ggccgttccg
    22381 tcagcctggt ggcggggggt gatgtgataa cggccgtgcc accggcgcgc ggtgcgggtg
    22441 ggggtgccgc gtccggtccg gacagtgccc gcagcaggcg gtccaggccc ttgcgatggc
    22501 gggcaaaggc gcggcgcggc gcccaccggc ctcgggcgtc ctggccggac aatgcctcgg
    22561 ccacccctac gtccagcacg atcagatgca gttcacgtcc ttggcgtccg gtatgtccgg
    22621 acagccatcg gcgcatccac ggt
//
